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Predict the Effect of Mutations on Clinical Drug Response
Note:
1. Please check in advance that the given protein is a drug target, or the results may be inaccurate.
2. If there are multiple mutations on the protein, please predict them separately. For example, if sequence A has mutations at both position 3 and position 9, then you should separately input the two sets of sequences, "Sequence A and sequence A with mutation at position 3" as well as "Sequence A and sequence A with mutation at position 9" into the model.
Step 1. Input the original protein sequence:
e.g.1 P31749 / e.g.2 MSDVAIVKEGWLHKRGEYI..(Use Example Run)
Step 2. Input the mutation information:
mutation position
e.g. E17K
Step 3. Input the standard pubchem drug name:
e.g. Vemurafenib
Reset
Example run