PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
TRAPPC1	0	TRAPPC4	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Boldt K (2016)	2
TRAPPC1	0	TRAPPC10	7	two hybrid, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Huttlin EL (2017), Boldt K (2016)	3
TRAPPC6A	0	TRAPPC6B	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC6A	0	TRAPPC12	4	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2015), Huttlin EL (2017)	4
TRAPPC5	0	TRAPPC1	0	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC5	0	TRAPPC6A	0	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC3L	0	TRAPPC9	6	two hybrid	Scrivens PJ (2011)	1
TRAPPC3L	0	TRAPPC1	0	two hybrid	Scrivens PJ (2011)	1
TRAPPC2	0	TRAPPC1	0	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC2	0	TRAPPC5	0	two hybrid, two hybrid, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2017)	3
TRAPPC8	3	TRAPPC9	6	two hybrid	Scrivens PJ (2011)	1
TRAPPC8	3	TRAPPC10	7	biochemical, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC2	0	TRAPPC11	1	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2017)	4
TRAPPC2	0	TRAPPC12	4	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2015), Huttlin EL (2017)	4
TRAPPC2L	0	TRAPPC11	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011), Scrivens PJ (2011)	3
TRAPPC4	2	TRAPPC10	7	two hybrid, affinity chromatography technology	Scrivens PJ (2011), Boldt K (2016)	2
TRAPPC6B	0	TRAPPC10	7	two hybrid	Scrivens PJ (2011)	1
TRAPPC2	0	TRAPPC8	3	affinity chromatography technology, biochemical, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2017)	3
TRAPPC3L	0	TRAPPC4	2	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC5	0	TRAPPC11	1	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC5	0	TRAPPC2L	0	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC12	4	TRAPPC10	7	two hybrid	Scrivens PJ (2011)	1
TRAPPC5	0	TRAPPC4	2	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC4	2	TRAPPC6B	0	biochemical	Wan C (2015)	1
TRAPPC2L	0	TRAPPC12	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Huttlin EL (2015), Huttlin EL (2017)	3
TRAPPC2L	0	TRAPPC6B	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC8	3	TRAPPC6B	0	two hybrid	Scrivens PJ (2011)	1
TRAPPC6A	0	TRAPPC10	7	two hybrid	Scrivens PJ (2011)	1
TRAPPC3L	0	TRAPPC10	7	two hybrid	Scrivens PJ (2011)	1
TRAPPC3L	0	TRAPPC6B	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC3L	0	TRAPPC6A	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC2	0	TRAPPC4	2	two hybrid, two hybrid, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2017)	3
TRAPPC3L	0	TRAPPC12	4	two hybrid	Scrivens PJ (2011)	1
TRAPPC2	0	TRAPPC2L	0	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC2L	0	TRAPPC8	3	affinity chromatography technology, affinity chromatography technology, biochemical	Choi C (2011), Scrivens PJ (2011), Scrivens PJ (2011)	3
TRAPPC3L	0	TRAPPC11	1	two hybrid	Scrivens PJ (2011)	1
TRAPPC1	0	TRAPPC12	4	two hybrid, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Huttlin EL (2015), Huttlin EL (2017)	3
TRAPPC4	2	TRAPPC2L	0	two hybrid, affinity chromatography technology	Scrivens PJ (2011), Boldt K (2016)	2
TRAPPC3L	0	TRAPPC8	3	two hybrid	Scrivens PJ (2011)	1
TRAPPC12	4	TRAPPC5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TRAPPC4	2	TRAPPC9	6	two hybrid, affinity chromatography technology	Scrivens PJ (2011), Boldt K (2016)	2
TRAPPC2	0	TRAPPC3L	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC5	0	TRAPPC10	7	two hybrid, affinity chromatography technology	Scrivens PJ (2011), Huttlin EL (2017)	2
TRAPPC12	4	TRAPPC6B	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Huttlin EL (2015), Huttlin EL (2017)	3
TRAPPC11	1	TRAPPC12	4	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2015), Huttlin EL (2017)	4
TRAPPC5	0	TRAPPC9	6	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC5	0	TRAPPC8	3	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC1	0	TRAPPC6B	0	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC8	3	TRAPPC11	1	biochemical, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC1	0	TRAPPC9	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Boldt K (2016)	2
TRAPPC2L	0	TRAPPC9	6	affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Boldt K (2016)	2
TRAPPC1	0	TRAPPC11	1	two hybrid, affinity chromatography technology	Scrivens PJ (2011), Huttlin EL (2017)	2
TRAPPC2	0	TRAPPC10	7	affinity chromatography technology, two hybrid, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2017)	3
TRAPPC9	6	TRAPPC10	7	two hybrid, affinity chromatography technology	Scrivens PJ (2011), Boldt K (2016)	2
TRAPPC4	2	TRAPPC12	4	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2015), Huttlin EL (2017)	4
TRAPPC1	0	TRAPPC8	3	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC2L	0	TRAPPC6A	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC2	0	TRAPPC6B	0	two hybrid, two hybrid, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2017)	3
TRAPPC2L	0	TRAPPC10	7	affinity chromatography technology, two hybrid, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Boldt K (2016)	3
TRAPPC3L	0	TRAPPC5	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC1	0	TRAPPC2L	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Boldt K (2016)	2
TRAPPC4	2	TRAPPC8	3	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC5	0	TRAPPC6B	0	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC2	0	TRAPPC6A	0	two hybrid, two hybrid, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2017)	3
TRAPPC9	6	TRAPPC12	4	two hybrid	Scrivens PJ (2011)	1
TRAPPC2L	0	TRAPPC3L	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC2	0	TRAPPC9	6	affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2017)	4
TRAPPC8	3	TRAPPC12	4	biochemical, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2015), Huttlin EL (2017)	5
TRAPPC4	2	TRAPPC11	1	two hybrid	Scrivens PJ (2011)	1
TRAPPC1	0	TRAPPC6A	0	affinity chromatography technology	Huttlin EL (2017)	1