PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
MLF2	1	BAG2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014)	5
TP53	0	TP73	2	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Stindt MH (2015), Puca R (2011), De Laurenzi V (1998), Di Como CJ (1999)	4
EGLN3	0	STIP1	1	affinity chromatography technology	Rodriguez J (2016)	1
CUL3	17	BAG4	2	affinity chromatography technology	Bennett EJ (2010)	1
MAPK6	1	STUB1	4	affinity chromatography technology	Rodriguez J (2016)	1
CUL2	3	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
MYC	2	XPO1	8	affinity chromatography technology, affinity chromatography technology	Koch HB (2007), Kirli K (2015)	2
XPO1	8	TP73	2	unspecified method	Xu D (2012)	1
MAPK6	1	BAG2	0	affinity chromatography technology	Rodriguez J (2016)	1
DNAJB6	3	APP	1	pull down	Olah J (2011)	1
CUL2	3	BAG4	2	affinity chromatography technology	Bennett EJ (2010)	1
APP	1	HSPA8	4	affinity chromatography technology	Yamamoto YH (2010)	1
NTRK1	1	UBC	7	affinity chromatography technology	Emdal KB (2015)	1
KRT18	2	DNAJB6	3	two hybrid, affinity chromatography technology, pull down	Izawa I (2000), Izawa I (2000), Izawa I (2000)	3
HSPA1A	0	HSPA8	4	biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012)	2
CYLD	2	HSPA6	1	affinity chromatography technology	Elliott PR (2016)	1
MAP3K1	4	FKBP5	0	affinity chromatography technology	Bouwmeester T (2004)	1
HSPA8	4	BAG2	0	two hybrid, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical	Takayama S (1999), Takayama S (1999), Takayama S (1999), Arndt V (2005), Arndt V (2005), Hegele A (2012), Hegele A (2012), Taipale M (2014), Taipale M (2014), Wan C (2015)	10
TP53	0	BAG1	1	genetic interference	Matsuzawa S (1998)	1
FBXO7	1	TARDBP	4	enzymatic study	Teixeira FR (2016)	1
TRIM25	5	MYC	2	affinity chromatography technology	Choudhury NR (2017)	1
CFTR	5	XPO1	8	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
CYLD	2	HDAC6	0	affinity chromatography technology, pull down, affinity chromatography technology	Wickstroem SA (2010), Wickstroem SA (2010), Sun L (2010)	3
RIPK4	0	MLF2	1	affinity chromatography technology	Rodriguez J (2016)	1
BAG4	2	HSPA8	4	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Miki K (2002), Miki K (2002), Taipale M (2014), Taipale M (2014)	4
FBXO7	1	DNAJB6	3	affinity chromatography technology	Teixeira FR (2016)	1
CFTR	5	HSPA8	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Meacham GC (1999), Younger JM (2004), Fuller W (2000), Rubenstein RC (2000), Matsumura Y (2011), Goldstein RF (2007), Goldstein RF (2007), Meacham GC (2001), Meacham GC (2001), Wang X (2006), Matsumura Y (2013), Zaman K (2006), Pankow S (2015)	13
XPO1	8	DNAJB6	3	affinity chromatography technology	Kirli K (2015)	1
FKBP5	0	APP	1	pull down	Olah J (2011)	1
TP63	0	DNAJB6	3	affinity chromatography technology	Lunardi A (2010)	1
XPO1	8	FBXO7	1	pull down	Nelson DE (2011)	1
TRIM25	5	APP	1	affinity chromatography technology	Choudhury NR (2017)	1
CUL3	17	BAG2	0	affinity chromatography technology	Bennett EJ (2010)	1
UBC	7	STUB1	4	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Connell P (2001), Connell P (2001), Windheim M (2008), Zhang M (2005)	4
CFTR	5	BAG2	0	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
CYLD	2	MATR3	2	affinity chromatography technology	Elliott PR (2016)	1
CFTR	5	BAG3	4	affinity chromatography technology	Pankow S (2015)	1
HDAC6	0	SIRT2	1	affinity chromatography technology	Nahhas F (2007)	1
CYLD	2	UBC	7	enzymatic study, enzymatic study, enzymatic study, pull down	Almeida S (2008), Bremm A (2010), Komander D (2009), Kwasna D (2018)	4
TP73	2	DNAJB6	3	affinity chromatography technology	Lunardi A (2010)	1
TP53	0	UBC	7	affinity chromatography technology, affinity chromatography technology	Ayroldi E (2014), Ke JY (2014)	2
TP53	0	CYLD	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Fernandez-Majada V (2016), Fernandez-Majada V (2016), Fernandez-Majada V (2016), Fernandez-Majada V (2016)	4
HDAC6	0	XPO1	8	affinity chromatography technology, affinity chromatography technology	Riolo MT (2012), Kirli K (2015)	2
MATR3	2	DNAJB6	3	affinity chromatography technology	Hein MY (2015)	1
ZNF746	0	DNAJB6	3	affinity chromatography technology	Kang H (2015)	1
ESRRB	1	DNAJB2	0	affinity chromatography technology	Li J (2013)	1
BAG1	1	DNAJB6	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
NTRK1	1	HSPA1A	0	affinity chromatography technology	Emdal KB (2015)	1
BAG3	4	STUB1	4	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kristensen AR (2012), Taipale M (2014), Taipale M (2014), Hein MY (2015)	4
RIPK4	0	FAM96B	0	affinity chromatography technology	Rodriguez J (2016)	1
FKBP5	0	DNAJB6	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
BRMS1	1	DNAJB6	3	two hybrid, affinity chromatography technology	Hurst DR (2006), Hurst DR (2006)	2
HSPA1A	0	BAG1	1	pull down	Shatkina L (2003)	1
HDAC6	0	UBC	7	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology	Pai MT (2007), Pozo FM (2011), Sekimoto T (2010), Kovacs JJ (2004), Hao R (2013), Lee JH (2013), Nakashima H (2014), Banerjee I (2014), Hao R (2013), Zhang X (2017), Yu Q (2018)	11
ESR1	0	STUB1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Fan M (2005), Tateishi Y (2004), Tateishi Y (2004), Tateishi Y (2004), Berry NB (2008), Dhamad AE (2016)	6
DUSP16	0	MLF1	2	affinity chromatography technology	Li X (2016)	1
HDAC6	0	STUB1	4	affinity chromatography technology	Cook C (2012)	1
XPO1	8	HIF1AN	0	affinity chromatography technology	Kirli K (2015)	1
DNAJB6	3	HDAC4	10	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hageman J (2010), Hageman J (2010), Pan Z (2008)	3
MAPK6	1	UBC	7	affinity chromatography technology	Rodriguez J (2016)	1
BAG2	0	DNAJB6	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
HSPA6	1	DNAJB6	3	affinity chromatography technology	Hageman J (2011)	1
DYNLT1	3	DNAJB6	3	bioid	Gupta GD (2015)	1
ESR1	0	KRT18	2	pull down	Nalvarte I (2010)	1
TP53	0	BAG2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014), Horikawa I (2014), Yue X (2016)	4
TRIM25	5	FBXO7	1	affinity chromatography technology	Choudhury NR (2017)	1
CYLD	2	TARDBP	4	affinity chromatography technology	Elliott PR (2016)	1
L3MBTL1	1	TP73	2	affinity chromatography technology	Huttlin EL (2017)	1
NTRK1	1	XPO1	8	affinity chromatography technology	Emdal KB (2015)	1
HDAC4	10	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
HSPA1A	0	DNAJB6	3	affinity chromatography technology	Hageman J (2011)	1
EGLN3	0	MAPK6	1	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang J (2011), Rodriguez J (2016), Rodriguez J (2016), Rodriguez J (2016), Rodriguez J (2016)	5
XPO1	8	CYLD	2	affinity chromatography technology	Kirli K (2015)	1
STIP1	1	BAG2	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
HIF1AN	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
TP53	0	STUB1	4	affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Muller P (2008), Stankiewicz M (2010), Tripathi V (2007), Tripathi V (2007), Esser C (2005), Lim JH (2011), Wang J (2011), Burch L (2004), Landre V (2013), Horikawa I (2014), Horikawa I (2014), Horikawa I (2014), Fraser JA (2015), Narayan V (2015), Yue X (2016), Parrales A (2016), Parrales A (2016)	17
HSPA1A	0	BAG2	0	affinity chromatography technology	Schoenbuehler B (2016)	1
TP73	2	MYC	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Uramoto H (2002), Uramoto H (2002), Uramoto H (2002), Watanabe K (2002), Watanabe K (2002)	5
DNAJB6	3	HSPB8	0	affinity chromatography technology	Sarparanta J (2012)	1
TARDBP	4	MATR3	2	affinity chromatography technology	Freibaum BD (2010)	1
MYC	2	DNAJB6	3	affinity chromatography technology	Koch HB (2007)	1
CUL2	3	UBC	7	affinity chromatography technology, affinity chromatography technology, enzymatic study	Bennett EJ (2010), Bish RA (2007), Wu K (2016)	3
UBC	7	BAG2	0	affinity chromatography technology	Matsumoto M (2005)	1
TP53	0	HSPA6	1	affinity chromatography technology	Horikawa I (2014)	1
ESR1	0	MYC	2	affinity chromatography technology	Cheng AS (2006)	1
TARDBP	4	APP	1	pull down	Olah J (2011)	1
RIPK4	0	FKBP5	0	affinity chromatography technology	Rodriguez J (2016)	1
BRMS1	1	CUL3	17	affinity chromatography technology	Kim B (2011)	1
RIPK4	0	HSPA6	1	affinity chromatography technology	Rodriguez J (2016)	1
TARDBP	4	HDAC6	0	affinity chromatography technology, affinity chromatography technology	Fiesel FC (2010), New M (2013)	2
BAG4	2	MLF2	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
SOX2	4	TP73	2	affinity chromatography technology	Cox JL (2013)	1
L3MBTL1	1	TP53	0	pull down, x-ray crystallography, affinity chromatography technology	West LE (2010), West LE (2010), West LE (2010)	3
CUL3	17	CUL2	3	biochemical	Wan C (2015)	1
ZNF746	0	TRIM25	5	affinity chromatography technology	Kang H (2015)	1
DNAJB2	0	TARDBP	4	affinity chromatography technology	Chen HJ (2016)	1
TRIM25	5	STUB1	4	affinity chromatography technology	Choudhury NR (2017)	1
NTRK1	1	DNAJB6	3	affinity chromatography technology	Emdal KB (2015)	1
FBXO7	1	BAG3	4	enzymatic study	Teixeira FR (2016)	1
EGLN3	0	POLR1D	4	affinity chromatography technology	Rodriguez J (2016)	1
MAPK6	1	DNAJB6	3	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	XPO1	8	affinity chromatography technology	Rodriguez J (2016)	1
MAPK6	1	HDAC11	0	two hybrid	Vinayagam A (2011)	1
STUB1	4	MLF2	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
APP	1	STUB1	4	affinity chromatography technology, affinity chromatography technology	Kumar P (2007), Kumar P (2007)	2
TRIM25	5	DNAJB6	3	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
BRAF	12	HSPA8	4	affinity chromatography technology	Gloeckner CJ (2007)	1
TRIM25	5	HSPA8	4	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
EGLN3	0	HSPA8	4	affinity chromatography technology	Rodriguez J (2016)	1
CFTR	5	TARDBP	4	affinity chromatography technology	Pankow S (2015)	1
HDAC11	0	DNAJB2	0	affinity chromatography technology	Joshi P (2013)	1
MAPK6	1	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
HSPA8	4	UBC	7	two hybrid	Stelzl U (2005)	1
MAP3K1	4	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Islam MR (2010), Islam MR (2010), Chipps E (2015), Chipps E (2015), Chipps E (2015)	5
BRAF	12	PIK3CA	8	genetic interference	Shen JP (2017)	1
NTRK1	1	CUL3	17	affinity chromatography technology	Emdal KB (2015)	1
BRMS1	1	HDAC6	0	affinity chromatography technology	Hurst DR (2006)	1
MYC	2	STUB1	4	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Paul I (2012), Paul I (2012), Paul I (2012), Huang H (2017)	4
HDAC6	0	CFTR	5	affinity chromatography technology, affinity chromatography technology	Kawaguchi Y (2003), Ouyang H (2012)	2
HIF1AN	0	MLF2	1	affinity chromatography technology	Rodriguez J (2016)	1
APP	1	MYC	2	pull down	Virok DP (2011)	1
ESRRB	1	HSPA8	4	affinity chromatography technology	Li J (2013)	1
MYC	2	HSPA1A	0	affinity chromatography technology	Agrawal P (2010)	1
FKBP5	0	STIP1	1	pull down	Li J (2011)	1
SOX2	4	BAG3	4	affinity chromatography technology	Cox JL (2013)	1
MLF1	2	TP73	2	affinity chromatography technology	Huttlin EL (2015)	1
TARDBP	4	HSPA8	4	affinity chromatography technology	Freibaum BD (2010)	1
DNAJB6	3	HDAC6	0	affinity chromatography technology, affinity chromatography technology	Hageman J (2010), Hageman J (2010)	2
CUL3	17	UBC	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Bennett EJ (2010), Olma MH (2009), Bish RA (2007), Wu K (2016)	4
HDAC11	0	BAG2	0	affinity chromatography technology	Joshi P (2013)	1
MYC	2	NTRK1	1	genetic interference	Toyoshima M (2012)	1
NTRK1	1	MATR3	2	affinity chromatography technology	Emdal KB (2015)	1
TARDBP	4	BAG2	0	affinity chromatography technology	Freibaum BD (2010)	1
XPO1	8	HSPB8	0	affinity chromatography technology	Kirli K (2015)	1
FBXO7	1	MATR3	2	affinity chromatography technology	Teixeira FR (2016)	1
BAG3	4	BAG2	0	affinity chromatography technology	Chen Y (2013)	1
TRIM25	5	HSPA1A	0	affinity chromatography technology, affinity chromatography technology	Pauli EK (2014), Choudhury NR (2017)	2
RIPK4	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
STIP1	1	DNAJB6	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
NTRK1	1	HSPA8	4	affinity chromatography technology	Emdal KB (2015)	1
EGLN3	0	MLF2	1	affinity chromatography technology	Rodriguez J (2016)	1
CFTR	5	TP53	0	affinity chromatography technology	Pankow S (2015)	1
XPO1	8	MLF2	1	affinity chromatography technology	Kirli K (2015)	1
HSPA8	4	BAG3	4	two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Takayama S (1999), Takayama S (1999), Takayama S (1999), Gentilella A (2011), Hishiya A (2011), Chen Y (2013), Chen Y (2013), Taipale M (2014), Taipale M (2014), Rolland T (2014), Hein MY (2015)	11
CUL3	17	TARDBP	4	affinity chromatography technology	Bennett EJ (2010)	1
TRIM25	5	POLR1D	4	affinity chromatography technology	Choudhury NR (2017)	1
CYLD	2	HSPA8	4	affinity chromatography technology	Elliott PR (2016)	1
BAG1	1	MLF2	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
TRIM25	5	MAPK6	1	affinity chromatography technology	Choudhury NR (2017)	1
ESRRB	1	HSPA1A	0	affinity chromatography technology	Li J (2013)	1
EGLN3	0	CYLD	2	affinity chromatography technology	Rodriguez J (2016)	1
ESR1	0	CUL3	17	affinity chromatography technology	Byun B (2008)	1
TP53	0	HSPA8	4	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Akakura S (2001), Kaur J (1996), Fogeron ML (2013), Horikawa I (2014), Matsumoto H (1994), Matsumoto H (1994), Karras GI (2017)	7
MLF1	2	DNAJB6	3	affinity chromatography technology	Huttlin EL (2015)	1
BRMS1	1	APP	1	pull down	Olah J (2011)	1
BAG4	2	STUB1	4	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
EGLN3	0	FAM96B	0	affinity chromatography technology	Rodriguez J (2016)	1
ESR1	0	HSPB8	0	affinity chromatography technology	Dhamad AE (2016)	1
STUB1	4	HSPA8	4	pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, pull down, pull down, pull down, pull down, affinity chromatography technology, enzymatic study, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, unspecified method, affinity chromatography technology, x-ray crystallography, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, enzymatic study	Ballinger CA (1999), Ballinger CA (1999), Ballinger CA (1999), Tateishi Y (2004), Tateishi Y (2004), Jiang J (2001), Wang L (2011), Wang L (2011), Wang L (2011), Stankiewicz M (2010), Yang M (2011), Yang M (2011), Urushitani M (2004), Grelle G (2006), Kim SA (2005), Arndt V (2005), Alberti S (2004), Meacham GC (2001), Smith MC (2013), Smith MC (2013), Matsumura Y (2013), Spooner RA (2008), Taipale M (2014), Taipale M (2014), Heimdal K (2014), Grelle G (2006), Grelle G (2006), Kamynina E (2007), Zhang H (2015), Zhang H (2015), Zhang H (2015), Li P (2015), Guo Y (2016), Zhang H (2017), Pakdaman Y (2017)	35
XPO1	8	ESR1	0	affinity chromatography technology	Castoria G (2012)	1
HDAC11	0	MLF2	1	affinity chromatography technology	Joshi P (2013)	1
TRIM25	5	MATR3	2	affinity chromatography technology	Choudhury NR (2017)	1
CFTR	5	HSPA1A	0	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
CUL3	17	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
NTRK1	1	MAP3K1	4	affinity chromatography technology	Emdal KB (2015)	1
CUL3	17	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
TP53	0	DNAJB6	3	affinity chromatography technology	Lunardi A (2010)	1
MLF2	1	HSPA6	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
TRIM25	5	XPO1	8	affinity chromatography technology	Choudhury NR (2017)	1
RIPK4	0	HSPA8	4	affinity chromatography technology	Rodriguez J (2016)	1
TRIM25	5	ESR1	0	affinity chromatography technology, pull down, enzymatic study	Nakajima A (2007), Nakajima A (2007), Nakajima A (2007)	3
STIP1	1	APP	1	pull down	Olah J (2011)	1
HSPA8	4	DNAJB6	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
TRIM25	5	EGLN3	0	affinity chromatography technology	Choudhury NR (2017)	1
HDAC6	0	HDAC11	0	affinity chromatography technology, affinity chromatography technology	Gao L (2002), Gao L (2002)	2
TARDBP	4	DNAJB6	3	affinity chromatography technology	Freibaum BD (2010)	1
BAG3	4	MLF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014), Hein MY (2015)	5
BAG3	4	HSPB8	0	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Taipale M (2014), Taipale M (2014), Yu H (2011), Hein MY (2015), Huttlin EL (2017)	6
BAG4	2	DNAJB6	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
HDAC11	0	DNAJB6	3	affinity chromatography technology	Joshi P (2013)	1
MAPK6	1	MLF2	1	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
TP53	0	POLR1D	4	genetic interference	Xie L (2013)	1
CFTR	5	KRT18	2	affinity chromatography technology	Pankow S (2015)	1
CUL2	3	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
HIF1AN	0	RIPK4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Rodriguez J (2016), Rodriguez J (2016), Rodriguez J (2016), Rodriguez J (2016)	5
TRIM25	5	STIP1	1	affinity chromatography technology	Choudhury NR (2017)	1
ESR1	0	DNAJB6	3	affinity chromatography technology	Dhamad AE (2016)	1
BAG3	4	HDAC6	0	affinity chromatography technology	Chen Y (2013)	1
EGLN3	0	DNAJB6	3	affinity chromatography technology	Rodriguez J (2016)	1
STUB1	4	DNAJB6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Sarparanta J (2012)	3
FAM96B	0	DNAJB6	3	affinity chromatography technology	Stehling O (2013)	1
ESR1	0	HSPA1A	0	affinity chromatography technology, affinity chromatography technology	Dhamad AE (2016), Dhamad AE (2016)	2
SOX2	4	BAG2	0	affinity chromatography technology	Cox JL (2013)	1
TP53	0	ESR1	0	pull down, affinity chromatography technology, affinity chromatography technology	Liu G (2000), Duong V (2007), Saxena R (2016)	3
EGLN3	0	STUB1	4	affinity chromatography technology	Rodriguez J (2016)	1
BAG3	4	DNAJB6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Sarparanta J (2012)	3
TRIM25	5	FKBP5	0	affinity chromatography technology	Choudhury NR (2017)	1
UBC	7	FBXO7	1	affinity chromatography technology	Matsumoto M (2005)	1
S100A4	0	TP53	0	pull down, affinity chromatography technology	Chen H (2001), Matsuura I (2010)	2
NTRK1	1	TARDBP	4	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	STIP1	1	affinity chromatography technology	Emdal KB (2015)	1
STUB1	4	BAG2	0	pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dai Q (2005), Dai Q (2005), Arndt V (2005), Arndt V (2005), Arndt V (2005), Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014)	9
SOX2	4	DNAJB6	3	affinity chromatography technology	Cox JL (2013)	1
CUL3	17	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
DYNLT1	3	APP	1	pull down	Olah J (2011)	1
ALKBH1	1	DNAJB6	3	affinity chromatography technology, affinity chromatography technology	Pan Z (2008), Pan Z (2008)	2
HSPA6	1	HSPA8	4	biochemical	Kristensen AR (2012)	1
TRIM25	5	MLF2	1	affinity chromatography technology	Choudhury NR (2017)	1
NTRK1	1	HDAC6	0	affinity chromatography technology	Emdal KB (2015)	1
HSPA1A	0	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kaur J (1996), Fogeron ML (2013), Horikawa I (2014), Matsumoto H (1994), Matsumoto H (1994)	5
CFTR	5	HSPA6	1	affinity chromatography technology	Wang X (2006)	1
ESR1	0	HSPA8	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Fan M (2005), Tateishi Y (2004), Ambrosino C (2010), Tarallo R (2011), Gebauer M (1998), Dhamad AE (2016), Dhamad AE (2016)	7
ZNF211	0	MLF2	1	affinity chromatography technology	Hauri S (2016)	1
DNAJB6	3	POLR1D	4	two hybrid	Wang J (2011)	1
DYNLT1	3	BAG3	4	pull down, biochemical	Gamerdinger M (2011), Gamerdinger M (2011)	2
RIPK4	0	STUB1	4	affinity chromatography technology	Rodriguez J (2016)	1
ZNF746	0	TARDBP	4	affinity chromatography technology	Kang H (2015)	1
MLF2	1	DNAJB6	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
ESR1	0	BAG1	1	pull down, affinity chromatography technology, affinity chromatography technology	Zeiner M (1995), Tateishi Y (2004), Berry NB (2008)	3
RIPK4	0	STIP1	1	affinity chromatography technology	Rodriguez J (2016)	1
STUB1	4	CFTR	5	enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Younger JM (2004), Summers DW (2009), Ren HY (2011), Meacham GC (2001), Schmidt BZ (2009), Alberti S (2004)	6
NTRK1	1	HSPA6	1	affinity chromatography technology	Emdal KB (2015)	1
BRMS1	1	HDAC4	10	affinity chromatography technology	Hurst DR (2006)	1
MAP3K1	4	DNAJB6	3	enzymatic study	Charlaftis N (2014)	1
ESR1	0	HSPA6	1	affinity chromatography technology	Dhamad AE (2016)	1
MYC	2	TP53	0	affinity chromatography technology, fluorescent resonance energy transfe	Agrawal P (2010), Ivanov AA (2017)	2
HIF1AN	0	DNAJB6	3	affinity chromatography technology	Rodriguez J (2016)	1
CUL2	3	DNAJB6	3	affinity chromatography technology	Bennett EJ (2010)	1
RIPK4	0	BAG2	0	affinity chromatography technology	Rodriguez J (2016)	1
ZNF211	0	DNAJB6	3	affinity chromatography technology	Hauri S (2016)	1
SOX2	4	XPO1	8	pull down	Baltus GA (2009)	1
HSPA1A	0	STIP1	1	biochemical, affinity chromatography technology	Wan C (2015), Scholz GM (2001)	2
TRIM25	5	C12orf45	0	affinity chromatography technology	Choudhury NR (2017)	1
BRAF	12	FKBP5	0	affinity chromatography technology	Eisenhardt AE (2016)	1
NTRK1	1	FKBP5	0	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	PIK3CA	8	affinity chromatography technology	Emdal KB (2015)	1
S100A4	0	DNAJB6	3	affinity chromatography technology	Hein MY (2015)	1
UBC	7	MATR3	2	affinity chromatography technology	Matsumoto M (2005)	1
CYLD	2	DNAJB2	0	affinity chromatography technology	Elliott PR (2016)	1
L3MBTL1	1	DNAJB6	3	affinity chromatography technology	Hauri S (2016)	1
STUB1	4	HSPA1A	0	pull down, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ballinger CA (1999), Ballinger CA (1999), Imai Y (2002), Havugimana PC (2012), Jinwal UK (2012), Yang SW (2013), Choi JR (2016), Schoenbuehler B (2016)	8
MAPK6	1	STIP1	1	affinity chromatography technology	Rodriguez J (2016)	1
SOX2	4	MLF2	1	affinity chromatography technology	Cox JL (2013)	1
CYLD	2	BAG2	0	affinity chromatography technology	Elliott PR (2016)	1
BAG1	1	BAG3	4	biochemical	Havugimana PC (2012)	1
HSPA1A	0	HSPA6	1	biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012)	2
STIP1	1	MLF2	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CUL3	17	DNAJB6	3	affinity chromatography technology	Bennett EJ (2010)	1
XPO1	8	SIRT2	1	unspecified method, affinity chromatography technology	Xu D (2012), Kirli K (2015)	2
TP53	0	TP63	0	genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McDade SS (2011), Lu D (2013), Chae YS (2012), Chae YS (2012), Stindt MH (2015), Wei S (2014)	6
DNAJB2	0	UBC	7	affinity chromatography technology, pull down, two hybrid	Westhoff B (2005), Fenner BJ (2009), Westhoff B (2005)	3
CFTR	5	DNAJB6	3	affinity chromatography technology	Pankow S (2015)	1
MLF2	1	FAM96B	0	affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Stehling O (2013)	2
ESR1	0	FKBP5	0	pull down, affinity chromatography technology	Nair SC (1996), Dhamad AE (2016)	2
XPO1	8	MAP3K1	4	affinity chromatography technology	Kirli K (2015)	1
CFTR	5	BAG1	1	affinity chromatography technology	Mendes F (2012)	1
NTRK1	1	CUL2	3	affinity chromatography technology	Emdal KB (2015)	1
ESR1	0	PIK3CA	8	affinity chromatography technology, affinity chromatography technology	Simoncini T (2000), Yoshimaru T (2013)	2
DUSP16	0	DNAJB6	3	affinity chromatography technology	Yadav L (2017)	1
MAPK6	1	HSPA8	4	affinity chromatography technology	Rodriguez J (2016)	1
BRAF	12	DNAJB6	3	affinity chromatography technology	Eisenhardt AE (2016)	1
TRIM25	5	TARDBP	4	affinity chromatography technology	Choudhury NR (2017)	1
HSPA8	4	STIP1	1	biochemical, far western blotting, pull down, pull down, pull down, biochemical	Havugimana PC (2012), Gebauer M (1998), Gebauer M (1998), Liu FH (1999), Tsukahara F (2000), Wan C (2015)	6
CUL3	17	MATR3	2	affinity chromatography technology	Bennett EJ (2010)	1
RIPK4	0	DNAJB6	3	affinity chromatography technology	Rodriguez J (2016)	1
HIF1AN	0	STUB1	4	affinity chromatography technology	Rodriguez J (2016)	1
CFTR	5	DNAJB2	0	affinity chromatography technology	Pankow S (2015)	1
DNAJB6	3	DNAJB2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UBC	7	DNAJB6	3	affinity chromatography technology	Matsumoto M (2005)	1
BAG1	1	STUB1	4	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Demand J (2001), Tateishi Y (2004), Tsukahara F (2010), Arndt V (2005), Taipale M (2014), Taipale M (2014), Narayan V (2015)	7
TRIM25	5	UBC	7	enzymatic study	Sanchez JG (2016)	1
HDAC6	0	KRT18	2	affinity chromatography technology	Watson GW (2016)	1
FAM96A	0	MLF2	1	affinity chromatography technology	Stehling O (2013)	1
ESRRB	1	DNAJB6	3	affinity chromatography technology	Li J (2013)	1
ESR1	0	HDAC4	10	pull down, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	van Rooij E (2010), Leong H (2005), Leong H (2005), Leong H (2005), Leong H (2005)	5
UBC	7	MLF2	1	affinity chromatography technology	Matsumoto M (2005)	1
CYLD	2	DNAJB6	3	affinity chromatography technology	Elliott PR (2016)	1
BAG3	4	HSPA1A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Doong H (2000), Antoku K (2001), Chen Y (2013), Hein MY (2015)	4
CYLD	2	BRAF	12	affinity chromatography technology	Elliott PR (2016)	1
BRAF	12	HSPA1A	0	affinity chromatography technology	Gloeckner CJ (2007)	1
PIK3CA	8	DNAJB6	3	two hybrid	Wang J (2008)	1
DNAJB6	3	SIRT2	1	affinity chromatography technology, affinity chromatography technology	Hageman J (2010), Hageman J (2010)	2
UBC	7	CEP164	6	pull down	Nathan JA (2013)	1
CUL3	17	DYNLT1	3	affinity chromatography technology	Bennett EJ (2010)	1
PIK3CA	8	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HDAC6	0	HSPA6	1	affinity chromatography technology	New M (2013)	1
BAG1	1	HSPA8	4	two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, unspecified method, x-ray crystallography, pull down, two hybrid, pull down, affinity chromatography technology	Takayama S (1997), Takayama S (1999), Takayama S (1999), Takayama S (1997), Takayama S (1997), Elliott E (2007), Alberti S (2002), Tsukahara F (2010), Brive L (2001), Lueders J (2000), Townsend PA (2003), Townsend PA (2003), Townsend PA (2004), Sharp A (2009), Sharp A (2009), Sondermann H (2001), Gebauer M (1998), Rolland T (2014), Mock JY (2015), Karras GI (2017)	20
HDAC6	0	HSPA8	4	affinity chromatography technology, affinity chromatography technology	New M (2013), Watson GW (2016)	2
TARDBP	4	CUL2	3	affinity chromatography technology, affinity chromatography technology	Uchida T (2016), Uchida T (2016)	2
DNAJB2	0	HSPA8	4	affinity chromatography technology	Westhoff B (2005)	1
DNAJB6	3	C12orf45	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CEP164	6	DNAJB6	3	bioid	Gupta GD (2015)	1
MAP3K1	4	DNAJB2	0	enzymatic study	Charlaftis N (2014)	1
TRIM25	5	BAG2	0	affinity chromatography technology	Choudhury NR (2017)	1
EGLN3	0	HSPA6	1	affinity chromatography technology	Rodriguez J (2016)	1
FAM96A	0	DNAJB6	3	affinity chromatography technology	Stehling O (2013)	1
TP63	0	TP73	2	affinity chromatography technology	Huttlin EL (2017)	1
RIPK4	0	XPO1	8	affinity chromatography technology	Rodriguez J (2016)	1
HDAC6	0	PIK3CA	8	genetic interference	Shen JP (2017)	1