PPI network (data source: BioGrid)

Symbol A GeneA coding DNM count Symbol B GeneB coding DNM count Interaction detection method Publication Evidence
LAT 0 MAP4K1 1 affinity chromatography technology, biochemical Ling P (2001), Ling P (2001) 2
LCE2D 0 KRTAP10-8 0 two hybrid Rolland T (2014) 1
SPRY1 2 KRTAP10-7 0 two hybrid Rolland T (2014) 1
SPRY1 2 STAT3 0 two hybrid Wang J (2011) 1
CREB5 4 KRTAP10-8 0 two hybrid Rolland T (2014) 1
HOXA1 4 KRTAP10-8 0 two hybrid Rolland T (2014) 1
KRTAP10-9 1 NOTCH2NL 1 two hybrid Rolland T (2014) 1
SPRY1 2 KRTAP10-3 1 two hybrid Rolland T (2014) 1
OTX1 4 KRTAP4-2 0 two hybrid Rolland T (2014) 1
CREB5 4 KRTAP10-7 0 two hybrid Rolland T (2014) 1
LCE1B 1 KRTAP10-8 0 two hybrid Rolland T (2014) 1
SPRY2 4 KRTAP10-9 1 two hybrid Rolland T (2014) 1
MDFI 1 SPRY2 4 two hybrid Rolland T (2014) 1
KRTAP10-8 0 KRTAP10-3 1 two hybrid Rolland T (2014) 1
LCE1B 1 KRTAP10-7 0 two hybrid Rolland T (2014) 1
SPRY1 2 CBLB 3 affinity chromatography technology Lee JS (2009) 1
SPRY1 2 KRTAP10-5 2 two hybrid Rolland T (2014) 1
GEMIN4 2 SPRY1 2 two hybrid Wang J (2011) 1
KRTAP10-5 2 KRTAP10-3 1 two hybrid Rolland T (2014) 1
KRTAP4-2 0 KRTAP10-5 2 two hybrid Rolland T (2014) 1
SPRY1 2 LCE2D 0 two hybrid Rolland T (2014) 1
SPRY1 2 GRB2 2 affinity chromatography technology Lao DH (2006) 1
MEOX2 2 KRTAP10-8 0 two hybrid Rolland T (2014) 1
SPRY2 4 CBL 7 pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Wong ES (2001), Wong ES (2001), Wong ES (2001), Wong ES (2002), Wong ES (2002), Ng C (2008), Ng C (2008), Chandramouli S (2008), Visser GD (2005), Hall AB (2003), Hall AB (2003), Rubin C (2003), Rubin C (2003), Rubin C (2003), Egan JE (2002), Miraoui H (2010), Mayer CE (2010), Sun Q (2010), Severe N (2011), Haglund K (2005), Lao DH (2007), Lao DH (2007), Fong CW (2003), Fong CW (2003), Mason JM (2004), DaSilva J (2006), Lao DH (2006) 27
CREB5 4 SPRY2 4 two hybrid Rolland T (2014) 1
PLCG1 6 LAT 0 biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, fluorescent resonance energy transfe Zhang W (1998), Paz PE (2001), Paz PE (2001), Zhang W (1998), Jiang Y (2007), Braiman A (2006), Braiman A (2006), Matalon O (2016), Matalon O (2016) 9
HRG 4 SPRY1 2 two hybrid Wang J (2011) 1
LCE1B 1 KRTAP10-3 1 two hybrid Rolland T (2014) 1
SPRY1 2 CBL 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Mason JM (2004), Lee JS (2009), Lao DH (2006) 3
SPRY1 2 YY1 7 two hybrid Wang J (2011) 1
STAT3 0 CBL 7 two hybrid Grossmann A (2015) 1
SPRY2 4 SH3KBP1 1 affinity chromatography technology, pull down, affinity chromatography technology, two hybrid Haglund K (2005), Haglund K (2005), Haglund K (2005), Rolland T (2014) 4
LCE1B 1 KRTAP10-5 2 two hybrid Rolland T (2014) 1
CBL 7 GRB2 2 affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Jain SK (1997), Liu SK (1998), Ettenberg SA (1999), Wong A (2002), Wong A (2002), Robertson H (1997), Donovan JA (1994), Park RK (1999), Erdreich-Epstein A (1999), Gesbert F (1998), Gesbert F (1998), Gesbert F (1998), Husson H (1997), Saci A (2002), Odai H (1997), Ng C (2008), Khan EM (2008), Bandyopadhyay S (2010), Jiang X (2003), Waterman H (2002), Miraoui H (2010), Ravid T (2004), Ingham RJ (1996), Erdreich-Epstein A (1997), Rellahan BL (2003), Izadi KD (1998), Wang Y (1999), Chu J (1998), Bonita DP (1997), Boussiotis VA (1997), Meisner H (1995), Meisner H (1995), Barber DL (1997), Shishido T (2000), Bartkiewicz M (1999), Buday L (1996), Tarcic G (2009), Belleudi F (2007), Brizzi MF (1996), Brenner B (2001), Donovan JA (1996), Donovan JA (1996), Donovan JA (1996), Gaston I (2004), Gaston I (2004), Tsygankov AY (1996), Tsygankov AY (1996), Hunter S (1997), Jain SK (1997), Levkowitz G (1996), Liu YC (1997), Odai H (1995), Odai H (1995), Meisner H (1995), Huang JY (2000), Panchamoorthy G (1996), Panchamoorthy G (1996), Yokouchi M (1997), Oda A (1996), Fukazawa T (1995), Fukazawa T (1995), Selbach M (2006), Brehme M (2009), Brehme M (2009), Fukazawa T (1995), Cerboni C (1998), Cerboni C (1998), Fixman ED (1997), Anderson SM (1997), Houtman JC (2006), Brizzi MF (1996), Scott RP (2005), Scott RP (2005), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Umehara H (2002), Taipale M (2014), Taipale M (2014), Grossmann A (2015), Grossmann A (2015), Igloi Z (2015), Huttlin EL (2017) 83
KRTAP4-2 0 KRTAP10-1 4 two hybrid Rolland T (2014) 1
MDFI 1 OTX1 4 two hybrid, two hybrid Rual JF (2005), Xin X (2009) 2
CBL 7 PLCG1 6 far western blotting, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique Tvorogov D (2002), Tvorogov D (2002), Tvorogov D (2002), Graham LJ (1998), Singh AJ (2007), Rellahan BL (2003), Rellahan BL (2003), Okabe S (2006), Choi JH (2003), Choi JH (2003), Braiman A (2006), Braiman A (2006), Braiman A (2006), Chen TC (2014) 14
CACNA1A 21 SPRY1 2 two hybrid Kahle JJ (2011) 1
KRTAP10-5 2 NOTCH2NL 1 two hybrid Rolland T (2014) 1
GRB2 2 SH3KBP1 1 pull down, pull down Gout I (2000), Borinstein SC (2000) 2
LAT 0 GRB2 2 affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down Paz PE (2001), Zhang W (1998), Perez-Villar JJ (2002), Motto DG (1994), Houtman JC (2006) 5
SPRY2 4 LCE2D 0 two hybrid Rolland T (2014) 1
SPRY2 4 GRB2 2 pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method Glienke J (2000), Chandramouli S (2008), Lao DH (2007), Mason JM (2004), Lao DH (2006), Lao DH (2006) 6
SPRY2 4 TESK1 2 affinity chromatography technology Chandramouli S (2008) 1
SH3KBP1 1 CBLB 3 two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, pull down Szymkiewicz I (2002), Szymkiewicz I (2002), Szymkiewicz I (2002), Havrylov S (2009), Moncalian G (2006), Jozic D (2005), Jozic D (2005), Kowanetz K (2003), Ceregido MA (2013), Ceregido MA (2013), Ceregido MA (2013) 11
BAG3 4 PLCG1 6 affinity chromatography technology, pull down, pull down Doong H (2000), Doong H (2000), Gentilella A (2011) 3
ELAVL1 0 SH3KBP1 1 affinity chromatography technology Abdelmohsen K (2009) 1
GRB2 2 KPNA2 0 two hybrid Wang J (2011) 1
OTX1 4 KRTAP10-8 0 two hybrid Rolland T (2014) 1
NEDD4 2 YY1 7 enzymatic study, affinity chromatography technology Persaud A (2009), Persaud A (2009) 2
MEOX2 2 KRTAP10-3 1 two hybrid Rolland T (2014) 1
LAT 0 CBL 7 affinity chromatography technology Jiang Y (2007) 1
OTX1 4 KRTAP10-9 1 two hybrid Rolland T (2014) 1
LCE2D 0 KRTAP10-5 2 two hybrid Rolland T (2014) 1
SPRY2 4 KRTAP10-5 2 two hybrid Rolland T (2014) 1
OTX1 4 LCE2D 0 two hybrid Rolland T (2014) 1
CREB5 4 KRTAP10-9 1 two hybrid Rolland T (2014) 1
HOXA1 4 SPRY1 2 two hybrid, two hybrid Rolland T (2014), Yu H (2011) 2
OTX1 4 KRTAP10-3 1 two hybrid Rolland T (2014) 1
NEDD4 2 CBLB 3 pull down, affinity chromatography technology, affinity chromatography technology Magnifico A (2003), Magnifico A (2003), Magnifico A (2003) 3
CREB5 4 SPRY1 2 two hybrid Rolland T (2014) 1
MEOX2 2 KRTAP10-5 2 two hybrid Rolland T (2014) 1
MEOX2 2 HEXIM2 0 two hybrid Rolland T (2014) 1
ELAVL1 0 SPRY2 4 affinity chromatography technology Abdelmohsen K (2009) 1
HOXA1 4 NOTCH2NL 1 two hybrid Rolland T (2014) 1
KRTAP10-7 0 KRTAP10-9 1 two hybrid Rolland T (2014) 1
GRB2 2 SOCS4 0 two hybrid, affinity chromatography technology Grossmann A (2015), Grossmann A (2015) 2
ELAVL1 0 SPRY1 2 affinity chromatography technology Abdelmohsen K (2009) 1
OTX1 4 KRTAP10-5 2 two hybrid Rolland T (2014) 1
CBL 7 CBLB 3 affinity chromatography technology, affinity chromatography technology Brehme M (2009), Rorsman C (2016) 2
TESK1 2 YY1 7 two hybrid Wang J (2011) 1
KRTAP4-2 0 KRTAP10-3 1 two hybrid Rolland T (2014) 1
ATXN7 0 SPRY1 2 two hybrid Kahle JJ (2011) 1
LCE1B 1 NOTCH2NL 1 two hybrid Rolland T (2014) 1
SPRY1 2 HEXIM2 0 two hybrid Rolland T (2014) 1
KRTAP10-9 1 KRTAP10-8 0 two hybrid Rolland T (2014) 1
CBLB 3 GRB2 2 affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology Ettenberg SA (1999), Lavagna-Sevenier C (1998), Lavagna-Sevenier C (1998), Elly C (1999), Bandyopadhyay S (2010), Vinayagam A (2011), Bisson N (2011), Blagoev B (2003), Rolland T (2014), Huttlin EL (2017) 10
STAT3 0 KRTAP10-7 0 two hybrid Grossmann A (2015) 1
KPNA2 0 SPRY1 2 two hybrid Wang J (2011) 1
BAG3 4 GRB2 2 affinity chromatography technology, affinity chromatography technology Chen Y (2013), Chen Y (2013) 2
HOXA1 4 LCE1B 1 two hybrid Rolland T (2014) 1
SPRY2 4 KRTAP10-8 0 two hybrid Rolland T (2014) 1
KRTAP10-1 4 NOTCH2NL 1 two hybrid Rolland T (2014) 1
SPRY2 4 LCE1B 1 two hybrid Rolland T (2014) 1
CREB5 4 KRTAP10-5 2 two hybrid Rolland T (2014) 1
ELAVL1 0 R3HDM2 2 affinity chromatography technology Abdelmohsen K (2009) 1
R3HDM2 2 KRTAP10-8 0 two hybrid Rolland T (2014) 1
SH3KBP1 1 CBL 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology Watanabe S (2000), Watanabe S (2000), Petrelli A (2002), Soubeyran P (2002), Soubeyran P (2002), Szymkiewicz I (2002), Borinstein SC (2000), Schmidt MH (2006), Schmidt MH (2004), Schmidt MH (2004), Verdier F (2002), Verdier F (2002), Feshchenko EA (2004), Chandra V (2010), Niiro H (2012), Feng L (2011), Havrylov S (2009), Zhang J (2009), Zhang J (2009), Ababou A (2009), Le Bras S (2007), Jozic D (2005), Kowanetz K (2004), Kowanetz K (2003), Kowanetz K (2003), Tibaldi EV (2003), Tibaldi EV (2003), Take H (2000), Take H (2000), Schroeder B (2012), Schroeder B (2012), Peruzzi G (2007), Selbach M (2006), Sato S (2013), Taipale M (2014), Taipale M (2014), Diesenberg K (2015), Petrelli A (2002), Huttlin EL (2017) 39
LCE1B 1 KRTAP10-9 1 two hybrid Rolland T (2014) 1
SPRY1 2 KRTAP10-9 1 two hybrid Rolland T (2014) 1
SPRY1 2 KRTAP4-2 0 two hybrid Rolland T (2014) 1
PLCG1 6 SPRY1 2 affinity chromatography technology Lee JS (2009) 1
SPRY2 4 KRTAP10-1 4 two hybrid Rolland T (2014) 1
NEDD4 2 SPRY1 2 affinity chromatography technology Edwin F (2010) 1
KRTAP10-1 4 KRTAP10-3 1 two hybrid Rolland T (2014) 1
KRTAP10-9 1 KRTAP10-3 1 two hybrid Rolland T (2014) 1
SPRY1 2 LAT 0 affinity chromatography technology, affinity chromatography technology Lee JS (2009), Lee JS (2009) 2
HOXA1 4 KRTAP10-9 1 two hybrid Rolland T (2014) 1
KRTAP4-2 0 KRTAP10-9 1 two hybrid Rolland T (2014) 1
KRTAP10-3 1 NOTCH2NL 1 two hybrid Rolland T (2014) 1
ELAVL1 0 GRB2 2 affinity chromatography technology Abdelmohsen K (2009) 1
HOXA1 4 KRTAP10-5 2 two hybrid Rolland T (2014) 1
KRTAP4-2 0 NOTCH2NL 1 two hybrid Rolland T (2014) 1
MDFI 1 CREB5 4 two hybrid Rolland T (2014) 1
R3HDM2 2 NOTCH2NL 1 two hybrid Rolland T (2014) 1
LCE1B 1 KRTAP10-1 4 two hybrid Rolland T (2014) 1
MEOX2 2 KRTAP4-2 0 two hybrid Rolland T (2014) 1
OTX1 4 SPRY2 4 two hybrid, two hybrid Rolland T (2014), Yu H (2011) 2
MAP4K1 1 SPRY1 2 affinity chromatography technology Lee JS (2009) 1
KRTAP10-7 0 KRTAP10-3 1 two hybrid Rolland T (2014) 1
SOCS4 0 SPRY1 2 two hybrid Wang J (2011) 1
MEOX2 2 SPRY1 2 two hybrid Rolland T (2014) 1
MEOX2 2 KRTAP10-9 1 two hybrid Rolland T (2014) 1
HOXA1 4 KRTAP10-3 1 two hybrid Rolland T (2014) 1
KPNA2 0 MDFI 1 two hybrid Rolland T (2014) 1
ELAVL1 0 YY1 7 affinity chromatography technology Abdelmohsen K (2009) 1
HOXA1 4 KRTAP4-2 0 two hybrid Rolland T (2014) 1
SH3KBP1 1 SPRY1 2 affinity chromatography technology Haglund K (2005) 1
HOXA1 4 KRTAP10-1 4 two hybrid Rolland T (2014) 1
KRTAP10-7 0 KRTAP10-5 2 two hybrid Rolland T (2014) 1
PLCG1 6 GRB2 2 affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology Pei Z (1997), Pei Z (1997), Nel AE (1995), Scholler JK (2000), Choi JH (2005), Choi JH (2005) 6
LCE2D 0 NOTCH2NL 1 two hybrid Rolland T (2014) 1
CREB5 4 KRTAP10-3 1 two hybrid Rolland T (2014) 1
SPRY1 2 R3HDM2 2 two hybrid Rolland T (2014) 1
MDFI 1 SPRY1 2 two hybrid Rolland T (2014) 1
SPRY1 2 KRTAP10-1 4 two hybrid Rolland T (2014) 1
KRTAP4-2 0 KRTAP10-7 0 two hybrid Rolland T (2014) 1
MEOX2 2 SPRY2 4 two hybrid Rolland T (2014) 1
GRB2 2 MAP4K1 1 pull down, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology Oehrl W (1998), Anafi M (1997), Anafi M (1997), Anafi M (1997), Ling P (1999), Ling P (2001) 6
OTX1 4 LCE1B 1 two hybrid Rolland T (2014) 1
BAG3 4 SPRY1 2 affinity chromatography technology Chen Y (2013) 1
KRTAP4-2 0 LCE1B 1 two hybrid Rolland T (2014) 1
OTX1 4 SPRY1 2 two hybrid Rolland T (2014) 1
MEOX2 2 LCE1B 1 two hybrid Rolland T (2014) 1
KRTAP10-7 0 KRTAP10-8 0 two hybrid Rolland T (2014) 1
CREB5 4 NOTCH2NL 1 two hybrid Rolland T (2014) 1
SPRY2 4 KRTAP10-3 1 two hybrid Rolland T (2014) 1
HOXA1 4 MDFI 1 two hybrid Rual JF (2005) 1
KRTAP10-7 0 NOTCH2NL 1 two hybrid Rolland T (2014) 1
MDFI 1 LCE1B 1 two hybrid Rolland T (2014) 1
SPRY1 2 NOTCH2NL 1 two hybrid Rolland T (2014) 1
MEOX2 2 KRTAP10-1 4 two hybrid Rolland T (2014) 1
SPRY2 4 SPRY1 2 affinity chromatography technology, two hybrid Mason JM (2004), Rolland T (2014) 2
KRTAP10-8 0 NOTCH2NL 1 two hybrid Rolland T (2014) 1
KRTAP4-2 0 KRTAP10-8 0 two hybrid Rolland T (2014) 1
OTX1 4 KRTAP10-1 4 two hybrid Rolland T (2014) 1
LCE2D 0 KRTAP10-9 1 two hybrid Rolland T (2014) 1
SPRY2 4 HEXIM2 0 two hybrid Rolland T (2014) 1
ELAVL1 0 STAT3 0 affinity chromatography technology Abdelmohsen K (2009) 1
CREB5 4 KRTAP4-2 0 two hybrid Rolland T (2014) 1
CREB5 4 KRTAP10-1 4 two hybrid Rolland T (2014) 1
SPRY2 4 NEDD4 2 affinity chromatography technology, affinity chromatography technology, pull down Edwin F (2010), Edwin F (2010), Edwin F (2010) 3
SPRY1 2 TESK1 2 affinity chromatography technology Chandramouli S (2008) 1
SPRY1 2 KRTAP10-8 0 two hybrid Rolland T (2014) 1
SPRY1 2 LCE1B 1 two hybrid Rolland T (2014) 1
R3HDM2 2 KRTAP10-3 1 two hybrid Rolland T (2014) 1