PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
GRAP2	0	STAMBP	2	two hybrid, two hybrid, pull down, unspecified method, two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Asada H (1999), Sierra MI (2010), Berry DM (2002), Tsang HT (2006), Huttlin EL (2015), Huttlin EL (2017)	7
CLINT1	1	CLTCL1	4	affinity chromatography technology	Huttlin EL (2017)	1
CHMP5	0	CHMP1B	0	two hybrid	Tsang HT (2006)	1
TRAF6	0	UBC	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Muroi M (2011), Park S (2013), Sun L (2004), Kanayama A (2004), Sakamoto H (2015), Yu J (2016), Middleton AJ (2017)	7
TP53	0	STAM2	0	genetic interference	Xie L (2013)	1
SMAD6	9	SMAD7	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Topper JN (1997), Topper JN (1997), Topper JN (1997), Yan X (2016)	4
CLTA	1	CLTC	12	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
TNFRSF1A	3	UBC	7	affinity chromatography technology	Nakazawa S (2016)	1
TRAF6	0	TP53	0	enzymatic study, affinity chromatography technology	Zhang X (2016), Zhang X (2016)	2
OTUB1	0	STAMBP	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009)	2
STAMBP	2	ALAS1	2	two hybrid	Tsang HT (2006)	1
OTUB1	0	IL1RL2	1	enzymatic study	Saha SS (2017)	1
CLTC	12	CHMP1B	0	affinity chromatography technology	Hein MY (2015)	1
SMAD7	1	SMURF2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Asano Y (2004), Kavsak P (2000), Lee YS (2008), Komuro A (2004), Chong PA (2010), Chong PA (2010), Chong PA (2010), Cai Y (2012), Cai Y (2012), Chong PA (2006), Al-Salihi MA (2012), Ogunjimi AA (2005), Aragon E (2012), Aragon E (2012), Colland F (2004), Zhang L (2013), Chandhoke AS (2015), Iyengar PV (2015), Elkouris M (2016)	19
VTI1B	0	CLINT1	1	affinity chromatography technology	Huttlin EL (2017)	1
USP21	2	USP28	3	enzymatic study, enzymatic study	Loch CM (2012), Loch CM (2012)	2
STAMBPL1	2	STAMBP	2	affinity chromatography technology	Huttlin EL (2017)	1
PJA1	1	USP28	3	enzymatic study	Loch CM (2012)	1
GAK	5	CLINT1	1	affinity chromatography technology	Hein MY (2015)	1
RNF11	0	STAMBP	2	two hybrid, pull down, affinity chromatography technology	Li H (2004), Li H (2004), Li H (2004)	3
STAMBP	2	TRAF6	0	enzymatic study	Bremm A (2010)	1
SMURF2	3	UBC	7	enzymatic study, affinity chromatography technology, enzymatic study, pull down, pull down	Maspero E (2013), Zhang L (2013), Kristariyanto YA (2015), Mari S (2014), Zhang Y (2017)	5
TP53	0	UBC	7	affinity chromatography technology, affinity chromatography technology	Ayroldi E (2014), Ke JY (2014)	2
CASR	2	STAMBP	2	two hybrid, affinity chromatography technology	Herrera-Vigenor F (2006), Herrera-Vigenor F (2006)	2
TP53	0	CLTC	12	affinity chromatography technology	Horikawa I (2014)	1
GTSE1	3	BMP2K	0	affinity chromatography technology	Hein MY (2015)	1
GTSE1	3	CLTA	1	affinity chromatography technology	Hein MY (2015)	1
CLINT1	1	RALBP1	2	affinity chromatography technology	Huttlin EL (2017)	1
STAMBP	2	CHMP1A	3	affinity chromatography technology, two hybrid, two hybrid, pull down, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Agromayor M (2006), Agromayor M (2006), Row PE (2007), Row PE (2007), Tsang HT (2006), Tsang HT (2006), Wang J (2011), Huttlin EL (2015), Huttlin EL (2017)	9
STAMBP	2	UACA	8	two hybrid	Tsang HT (2006)	1
TP53	0	CLTA	1	affinity chromatography technology	Horikawa I (2014)	1
UBC	7	PJA1	1	affinity chromatography technology	Matsumoto M (2005)	1
CHMP4B	2	CHMP2A	3	imaging technique, affinity chromatography technology	Olmos Y (2015), Hein MY (2015)	2
GJA1	0	STAMBP	2	affinity chromatography technology, imaging technique	Ribeiro-Rodrigues TM (2014), Ribeiro-Rodrigues TM (2014)	2
RNASEH2B	0	STAMBP	2	affinity chromatography technology	Hein MY (2015)	1
STAMBP	2	CLINT1	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2017)	2
STAMBP	2	CHMP1B	0	affinity chromatography technology, two hybrid, two hybrid, pull down, two hybrid, two hybrid, imaging technique, affinity chromatography technology, two hybrid, two hybrid	Agromayor M (2006), Agromayor M (2006), Row PE (2007), Row PE (2007), Tsang HT (2006), Tsang HT (2006), Tsang HT (2006), Tsang HT (2006), Wang J (2011), Rolland T (2014)	10
SMAD7	1	TP53	0	affinity chromatography technology	Zhang S (2006)	1
GTSE1	3	RALBP1	2	affinity chromatography technology	Hein MY (2015)	1
PIK3C2A	7	CLTA	1	biochemical	Wan C (2015)	1
STAMBPL1	2	OTUB1	0	affinity chromatography technology	Sowa ME (2009)	1
GTSE1	3	CLTC	12	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
STAM	3	STAMBP	2	pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, enzymatic study, pull down	Kato M (2000), Tanaka N (1999), Tanaka N (1999), Tanaka N (1999), Kim MS (2006), Agromayor M (2006), McCullough J (2004), Sierra MI (2010), Sierra MI (2010), Sierra MI (2010), Row PE (2006), Kikuchi K (2003), McCullough J (2006), McCullough J (2006), Tsang HT (2006), Davies CW (2013), Davies CW (2013), McCullough J (2006)	18
USP28	3	STAM	3	enzymatic study	Loch CM (2012)	1
USP28	3	UBC	7	enzymatic study, enzymatic study, x-ray crystallography, enzymatic study, pull down, enzymatic study, pull down	Loch CM (2012), Zhen Y (2014), Wen Y (2015), Wen Y (2015), Wen Y (2015), Wrigley JD (2017), Kwasna D (2018)	7
PSMD7	1	STAMBP	2	biochemical	Wan C (2015)	1
PJA1	1	STAMBP	2	enzymatic study	Loch CM (2012)	1
GRB2	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Bennett AM (1994), Ward AC (1998), Yin T (1997), Tang J (1997), Tang H (1999), Hadari YR (1998), Zhang S (1999), Wong L (1996), Brehme M (2009), Craddock BL (1997), Bisson N (2011), Blagoev B (2003), Bisson N (2011), Tauchi T (1995), Huttlin EL (2017), Kapoor GS (2010), Kapoor GS (2010), Vogel W (1996), Vogel W (1996), Yu WM (2006)	21
GAK	5	STAMBPL1	2	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
GTSE1	3	PIK3C2A	7	affinity chromatography technology	Hein MY (2015)	1
STAMBP	2	VTI1B	0	affinity chromatography technology	Huttlin EL (2017)	1
STAMBPL1	2	CLTC	12	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Nakamura M (2006), Nakamura M (2006), Hein MY (2015), Huttlin EL (2017)	4
CHMP3	0	CHMP1B	0	biochemical	Wan C (2015)	1
STAMBP	2	PIK3C2A	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2015), Huttlin EL (2017)	3
GTSE1	3	AP2A1	1	affinity chromatography technology	Hein MY (2015)	1
GRB2	2	AP2A1	1	affinity chromatography technology	Blagoev B (2003)	1
GAK	5	AP2A1	1	affinity chromatography technology	Hein MY (2015)	1
STAMBP	2	3501	0	affinity chromatography technology	Huttlin EL (2017)	1
SLC25A41	0	BMP2K	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
STAMBP	2	CTNNBL1	1	two hybrid	Tsang HT (2006)	1
CDKL3	1	STAMBP	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GTSE1	3	VTI1B	0	affinity chromatography technology	Hein MY (2015)	1
CLTC	12	CLTCL1	4	affinity chromatography technology	Hein MY (2015)	1
UBC	7	PSMD7	1	affinity chromatography technology, pull down	Matsumoto M (2005), Zhang X (2017)	2
GRB2	2	UBC	7	two hybrid	Bandyopadhyay S (2010)	1
STAM	3	UBC	7	pull down, affinity chromatography technology, x-ray crystallography, pull down, pull down, pull down, unspecified method, pull down, pull down, x-ray crystallography, pull down	Kim MS (2006), Mizuno E (2006), Hong YH (2009), Nathan JA (2013), Nathan JA (2013), Stuible M (2010), Lim J (2011), Baiady N (2016), Kharitidi D (2015), Sundd M (2012), Zhang X (2017)	11
CHMP3	0	CHMP4B	2	two hybrid, two hybrid, biochemical, affinity chromatography technology	Tsang HT (2006), Tsang HT (2006), Wan C (2015), Hein MY (2015)	4
STAMBP	2	AMN	0	two hybrid	Tsang HT (2006)	1
CHMP4A	1	CHMP3	0	two hybrid	von Schwedler UK (2003)	1
STAMBPL1	2	CLTCL1	4	affinity chromatography technology	Huttlin EL (2017)	1
STAMBP	2	GAK	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GTSE1	3	STAMBP	2	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
GAK	5	CLTCL1	4	affinity chromatography technology	Hein MY (2015)	1
UBC	7	AP2A1	1	pull down	Zhang X (2017)	1
RDH12	0	STAMBP	2	affinity chromatography technology	Huttlin EL (2017)	1
RNF11	0	SMURF2	3	pull down, affinity chromatography technology, two hybrid, two hybrid	Subramaniam V (2003), Santonico E (2010), Colland F (2004), Colland F (2004)	4
USP21	2	TRAF6	0	enzymatic study	Bremm A (2010)	1
CHMP5	0	STAMBP	2	two hybrid	Wang J (2011)	1
CHMP4C	1	CHMP1B	0	biochemical	Wan C (2015)	1
CHMP1A	3	CHMP1B	0	two hybrid, two hybrid	von Schwedler UK (2003), Tsang HT (2006)	2
STAMBP	2	MAP3K2	1	enzymatic study	Takeda AN (2014)	1
STAM	3	STAM2	0	imaging technique	Kanazawa C (2003)	1
STAMBP	2	TRIP13	0	two hybrid	Venkatesan K (2009)	1
GTSE1	3	GAK	5	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
STAMBP	2	TNFRSF1A	3	enzymatic study	Fritsch J (2014)	1
TRAF6	0	PSMD7	1	affinity chromatography technology	Bouwmeester T (2004)	1
CLTC	12	CHMP1A	3	affinity chromatography technology	Hein MY (2015)	1
GAK	5	CLTA	1	affinity chromatography technology	Hein MY (2015)	1
CLTC	12	BMP2K	0	affinity chromatography technology	Hein MY (2015)	1
STAMBP	2	CLTC	12	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Nakamura M (2006), Nakamura M (2006), McCullough J (2006), McCullough J (2006), McCullough J (2006), Hein MY (2015)	6
STAMBP	2	CHMP4A	1	two hybrid, two hybrid	Row PE (2007), Tsang HT (2006)	2
CLINT1	1	BMP2K	0	affinity chromatography technology	Huttlin EL (2017)	1
MAP2K5	1	TP53	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STAMBP	2	SMAD6	9	affinity chromatography technology, two hybrid, two hybrid	Itoh F (2001), Itoh F (2001), Itoh F (2001)	3
CLTA	1	CLTCL1	4	biochemical	Wan C (2015)	1
USP28	3	OTUB1	0	enzymatic study	Loch CM (2012)	1
STAMBP	2	UBC	7	enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, x-ray crystallography, enzymatic study, pull down, enzymatic study, enzymatic study	Bremm A (2010), Komander D (2009), McCullough J (2006), Nakasone MA (2013), Davies CW (2013), Trang VH (2014), Wauer T (2015), Michel MA (2015), Bueno AN (2015), Baiady N (2016), Baiady N (2016), Castaneda CA (2016), Kliza K (2017)	13
STAMBPL1	2	BMP2K	0	affinity chromatography technology	Huttlin EL (2017)	1
STAMBP	2	AP2A1	1	affinity chromatography technology	Huttlin EL (2017)	1
SMURF2	3	STAMBP	2	affinity chromatography technology, affinity chromatography technology	Li H (2004), Li H (2004)	2
STAMBP	2	MAP2K5	1	two hybrid	Tsang HT (2006)	1
CLTC	12	PIK3C2A	7	affinity chromatography technology	Hein MY (2015)	1
STAMBP	2	UBE2S	2	enzymatic study	Bremm A (2010)	1
GAK	5	PIK3C2A	7	affinity chromatography technology	Hein MY (2015)	1
STAMBP	2	FDPS	0	biochemical	Kristensen AR (2012)	1
CHMP4B	2	CHMP1A	3	affinity chromatography technology	Hein MY (2015)	1
CLINT1	1	PIK3C2A	7	affinity chromatography technology	Huttlin EL (2017)	1
USP21	2	STAMBP	2	enzymatic study	Loch CM (2012)	1
CHMP4B	2	CHMP4A	1	two hybrid	Tsang HT (2006)	1
STAMBP	2	PTPN11	20	biochemical	Wan C (2015)	1
SLC25A41	0	STAMBP	2	affinity chromatography technology	Huttlin EL (2017)	1
ITGA5	7	UBC	7	affinity chromatography technology	Kaabeche K (2005)	1
STAM2	0	STAMBP	2	two hybrid, affinity chromatography technology, pull down, two hybrid, two hybrid, x-ray crystallography	Rual JF (2005), Sierra MI (2010), Sierra MI (2010), Tsang HT (2006), Venkatesan K (2009), Hologne M (2016)	6
GAK	5	CLTC	12	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
KIF7	3	STAMBP	2	affinity chromatography technology	Hein MY (2015)	1
STAMBP	2	CHMP4B	2	two hybrid, two hybrid, two hybrid	Row PE (2007), Tsang HT (2006), Tsang HT (2006)	3
USP21	2	UBE2S	2	enzymatic study	Bremm A (2010)	1
RNF11	0	PSMD7	1	affinity chromatography technology	Poulsen SL (2013)	1
CLINT1	1	CLTC	12	pull down, pull down, affinity chromatography technology	Kalthoff C (2002), Mills IG (2003), Hein MY (2015)	3
STAMBP	2	CLTCL1	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PJA1	1	STAM	3	enzymatic study	Loch CM (2012)	1
CHMP5	0	CHMP4B	2	two hybrid, biochemical, affinity chromatography technology	Tsang HT (2006), Wan C (2015), Hein MY (2015)	3
STAMBP	2	RALBP1	2	affinity chromatography technology	Huttlin EL (2017)	1
STAMBP	2	SMAD7	1	affinity chromatography technology, two hybrid	Itoh F (2001), Itoh F (2001)	2
CHMP4C	1	CHMP4A	1	two hybrid	von Schwedler UK (2003)	1
GTSE1	3	STAMBPL1	2	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
STAMBP	2	AFP	1	affinity chromatography technology	Sowa ME (2009)	1
GRB2	2	TNFRSF1A	3	affinity chromatography technology, affinity chromatography technology	Hildt E (1999), Kurada BR (2009)	2
STAMBP	2	CLTA	1	affinity chromatography technology	Sowa ME (2009)	1
CHMP4C	1	CHMP4B	2	two hybrid, two hybrid	von Schwedler UK (2003), Tsang HT (2006)	2
RALBP1	2	BMP2K	0	affinity chromatography technology	Huttlin EL (2017)	1
SPG7	6	STAMBP	2	two hybrid	Wang J (2011)	1
STAM2	0	UBC	7	x-ray crystallography, x-ray crystallography, pull down, pull down, pull down, pull down, pull down	Lange A (2010), Lange A (2012), Lange A (2012), Stuible M (2010), Baiady N (2016), Zhang X (2017), Hologne M (2016)	7
TNFRSF1A	3	TRAF6	0	affinity chromatography technology	Chang YL (2014)	1
GTSE1	3	CLINT1	1	affinity chromatography technology	Hein MY (2015)	1
UBE2S	2	UBC	7	enzymatic study, pull down, x-ray crystallography, enzymatic study, enzymatic study	Bremm A (2010), Wickliffe KE (2011), Wickliffe KE (2011), Kelly A (2014), Michel MA (2017)	5
CHMP2A	3	STAMBP	2	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Kyuuma M (2006), Agromayor M (2006), Agromayor M (2006), Huttlin EL (2017)	4
SLC25A41	0	AP2A1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
STAMBPL1	2	PIK3C2A	7	affinity chromatography technology	Huttlin EL (2017)	1
VAMP8	0	STAMBP	2	affinity chromatography technology	Mukai A (2008)	1
CHMP5	0	CHMP3	0	affinity chromatography technology	Huttlin EL (2017)	1
USP21	2	TP53	0	enzymatic study	Fernandez-Majada V (2016)	1
AP2A1	1	RALBP1	2	affinity chromatography technology, affinity chromatography technology	Kariya K (2000), Huttlin EL (2017)	2
USP21	2	OTUB1	0	enzymatic study	Loch CM (2012)	1
GAK	5	BMP2K	0	affinity chromatography technology	Hein MY (2015)	1
NTPCR	2	STAMBP	2	two hybrid	Wang J (2011)	1
GRB2	2	CLTC	12	affinity chromatography technology	Brehme M (2009)	1
PJA1	1	OTUB1	0	enzymatic study	Loch CM (2012)	1
STAMBP	2	GRB2	2	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bandyopadhyay S (2010), Sierra MI (2010), Sierra MI (2010), Sierra MI (2010), Kikuchi K (2003), Tsang HT (2006), Bisson N (2011), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	11
STAMBP	2	CHMP4C	1	pull down	Row PE (2007)	1
CYP2C9	3	STAMBP	2	two hybrid	Wang J (2011)	1
STAMBP	2	TP53	0	enzymatic study	Fernandez-Majada V (2016)	1
SLC25A41	0	PIK3C2A	7	affinity chromatography technology	Huttlin EL (2015)	1
STAMBPL1	2	CLINT1	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2017)	2
CHMP2A	3	CHMP5	0	affinity chromatography technology	Huttlin EL (2017)	1
STAMBP	2	CHMP3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, two hybrid, imaging technique, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Sowa ME (2009), Kyuuma M (2006), Kyuuma M (2006), Kyuuma M (2006), Agromayor M (2006), Agromayor M (2006), Row PE (2007), Row PE (2007), Ma YM (2007), Ma YM (2007), McCullough J (2006), Zamborlini A (2006), Tsang HT (2006), Tsang HT (2006), Tsang HT (2006), Tsang HT (2006), Rolland T (2014), Huttlin EL (2015), Lata S (2008), Huttlin EL (2017)	20
STAMBPL1	2	UBC	7	x-ray crystallography	Sato Y (2008)	1
OTUB1	0	UBC	7	enzymatic study, enzymatic study, x-ray crystallography, unspecified method, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, x-ray crystallography, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, pull down	Wang T (2009), Bremm A (2010), Juang YC (2012), Ernst A (2013), Ernst A (2013), Nakasone MA (2013), Wiener R (2013), Edelmann MJ (2009), Bish RA (2007), Mevissen TE (2013), Juang YC (2012), Herhaus L (2013), Ernst A (2013), Herhaus L (2015), Herhaus L (2015), Herhaus L (2015), Wauer T (2015), Michel MA (2015), Kristariyanto YA (2015), Scholz CC (2016), Scholz CC (2016), Altun M (2015), Flierman D (2016), Castaneda CA (2016), Zhang X (2017), Kwasna D (2018)	26
RNF11	0	STAM2	0	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down	Kostaras E (2012), Colland F (2004), Kostaras E (2014), Kostaras E (2012)	4
CHMP5	0	CHMP4A	1	two hybrid, biochemical	Tsang HT (2006), Wan C (2015)	2
CHMP4B	2	CHMP1B	0	two hybrid, biochemical, affinity chromatography technology	Tsang HT (2006), Wan C (2015), Hein MY (2015)	3
SLC25A41	0	RALBP1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TP53	0	OTUB1	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Sun XX (2011), Sun XX (2011), Sun XX (2011), Li Y (2014), Fernandez-Majada V (2016)	5
TP53	0	CHMP4B	2	affinity chromatography technology	Horikawa I (2014)	1
OTUB1	0	TRAF6	0	affinity chromatography technology, enzymatic study	Li S (2010), Bremm A (2010)	2
FDPS	0	ALAS1	2	affinity chromatography technology	Huttlin EL (2017)	1
CLINT1	1	AP2A1	1	pull down, affinity chromatography technology	Kalthoff C (2002), Huttlin EL (2017)	2
CLTC	12	STAM	3	affinity chromatography technology, pull down	Nakamura M (2006), McCullough J (2006)	2
CHMP2A	3	CHMP3	0	affinity chromatography technology, two hybrid	Kyuuma M (2006), Tsang HT (2006)	2
CLTC	12	VTI1B	0	affinity chromatography technology	Hein MY (2015)	1
STAMBP	2	BMP2K	0	affinity chromatography technology	Huttlin EL (2017)	1
ODF3L1	0	STAMBP	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MAP3K2	1	MAP2K5	1	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology	Sun W (2001), Sun W (2001), Nakamura K (2010), Nakamura K (2010), Wang J (2011), Takeda AN (2014), Takeda AN (2014), Takeda AN (2014), Takeda AN (2014), Huttlin EL (2017)	10
USP28	3	STAMBP	2	enzymatic study	Loch CM (2012)	1
OTUB1	0	UBE2S	2	enzymatic study	Bremm A (2010)	1
STAMBP	2	IL1RL2	1	enzymatic study	Saha SS (2017)	1
SMAD6	9	SMURF2	3	affinity chromatography technology, two hybrid, affinity chromatography technology	Komuro A (2004), Colland F (2004), Herhaus L (2014)	3
RALBP1	2	KIF7	3	affinity chromatography technology	Huttlin EL (2017)	1
STAMBPL1	2	VTI1B	0	affinity chromatography technology	Huttlin EL (2017)	1
CCDC58	0	STAMBP	2	biochemical	Wan C (2015)	1
RNF11	0	UBC	7	two hybrid, two hybrid	Li H (2004), Colland F (2004)	2
CHMP5	0	CHMP1A	3	affinity chromatography technology	Huttlin EL (2017)	1
GAK	5	CHMP4A	1	affinity chromatography technology	Hein MY (2015)	1
RNF11	0	AP2A1	1	affinity chromatography technology	Poulsen SL (2013)	1
ITGA5	7	STAMBP	2	two hybrid	Wang J (2011)	1
CLTC	12	AP2A1	1	affinity chromatography technology	Hein MY (2015)	1
USP21	2	UBC	7	enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, unspecified method, enzymatic study, enzymatic study, pull down, enzymatic study	Bremm A (2010), Faesen AC (2011), Ye Y (2011), Urbe S (2012), Loch CM (2012), Ernst A (2013), Ye Y (2011), Wauer T (2015), Leung I (2016), Michel MA (2017)	10
TRIP13	0	STAMBPL1	2	two hybrid	Rual JF (2005)	1
GTSE1	3	CLTCL1	4	affinity chromatography technology	Hein MY (2015)	1
CLTC	12	CHMP4B	2	affinity chromatography technology	Hein MY (2015)	1