Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
STIP1	rs6591838	G	corticosteroids	efficacy	no	The drugs were fluticasone furoate (82% of patients) and fluticasone propionate (18%). Response was assessed as change in FEV1 from baseline over 8 weeks (or 12 for HZA106837). The cohort was the meta-analysis of a combination of 7 randomized, double-blind, placebo-controlled, parallel-group, multi center studies conducted in 26 countries. They included FFA109684, FFA109685, FFA109687, FFA112059, HZA106827, HZA106829, and HZA106837.	Allele G is not associated with response to corticosteroids in people with Asthma as compared to allele A.	27523435	1448258070
STIP1	rs4980524	C	corticosteroids	efficacy	no	The drugs were fluticasone furoate (82% of patients) and fluticasone propionate (18%). Response was assessed as change in FEV1 from baseline over 8 weeks (or 12 for HZA106837). The cohort was the meta-analysis of a combination of 7 randomized, double-blind, placebo-controlled, parallel-group, multi center studies conducted in 26 countries. They included FFA109684, FFA109685, FFA109687, FFA112059, HZA106827, HZA106829, and HZA106837.	Allele C is not associated with response to corticosteroids in people with Asthma as compared to allele A.	27523435	1448258061
STIP1	rs3751123	A	corticosteroids	efficacy	no	The drugs were fluticasone furoate (82% of patients) and fluticasone propionate (18%). Response was assessed as change in FEV1 from baseline over 8 weeks (or 12 for HZA106837). The cohort was the meta-analysis of a combination of 7 randomized, double-blind, placebo-controlled, parallel-group, multi center studies conducted in 26 countries. They included FFA109684, FFA109685, FFA109687, FFA112059, HZA106827, HZA106829, and HZA106837.	Allele A is not associated with response to corticosteroids in people with Asthma as compared to allele G.	27523435	1448258025
STIP1	rs2701528	G	corticosteroids	efficacy	no	The drugs were fluticasone furoate (82% of patients) and fluticasone propionate (18%). Response was assessed as change in FEV1 from baseline over 8 weeks (or 12 for HZA106837). The cohort was the meta-analysis of a combination of 7 randomized, double-blind, placebo-controlled, parallel-group, multi center studies conducted in 26 countries. They included FFA109684, FFA109685, FFA109687, FFA112059, HZA106827, HZA106829, and HZA106837.	Allele G is not associated with response to corticosteroids in people with Asthma as compared to allele A.	27523435	1448258044
STIP1	rs2282490	C	corticosteroids	efficacy	no	The drugs were fluticasone furoate (82% of patients) and fluticasone propionate (18%). Response was assessed as change in FEV1 from baseline over 8 weeks (or 12 for HZA106837). The cohort was the meta-analysis of a combination of 7 randomized, double-blind, placebo-controlled, parallel-group, multi center studies conducted in 26 countries. They included FFA109684, FFA109685, FFA109687, FFA112059, HZA106827, HZA106829, and HZA106837.	Allele C is not associated with response to corticosteroids in people with Asthma as compared to allele T.	27523435	1448258082
STIP1	rs11607165	G	corticosteroids	efficacy	no	The drugs were fluticasone furoate (82% of patients) and fluticasone propionate (18%). Response was assessed as change in FEV1 from baseline over 8 weeks (or 12 for HZA106837). The cohort was the meta-analysis of a combination of 7 randomized, double-blind, placebo-controlled, parallel-group, multi center studies conducted in 26 countries. They included FFA109684, FFA109685, FFA109687, FFA112059, HZA106827, HZA106829, and HZA106837.	Allele G is not associated with response to corticosteroids in people with Asthma as compared to allele T.	27523435	1448258091
STIP1	rs2236647	C	corticosteroids	efficacy	no	The drugs were fluticasone furoate (82% of patients) and fluticasone propionate (18%). Response was assessed as change in FEV1 from baseline over 8 weeks (or 12 for HZA106837). The cohort was the meta-analysis of a combination of 7 randomized, double-blind, placebo-controlled, parallel-group, multi center studies conducted in 26 countries. They included FFA109684, FFA109685, FFA109687, FFA112059, HZA106827, HZA106829, and HZA106837.	Allele C is not associated with response to corticosteroids in people with Asthma as compared to allele T.	27523435	1448258104
STIP1	rs2236648	T	corticosteroids	efficacy	no	The drugs were fluticasone furoate (82% of patients) and fluticasone propionate (18%). Response was assessed as change in FEV1 from baseline over 8 weeks (or 12 for HZA106837). The cohort was the meta-analysis of a combination of 7 randomized, double-blind, placebo-controlled, parallel-group, multi center studies conducted in 26 countries. They included FFA109684, FFA109685, FFA109687, FFA112059, HZA106827, HZA106829, and HZA106837.	Allele T is not associated with response to corticosteroids in people with Asthma as compared to allele C.	27523435	1448258117
STIP1	rs2070232	A	corticosteroids	efficacy	no	The drugs were fluticasone furoate (82% of patients) and fluticasone propionate (18%). Response was assessed as change in FEV1 from baseline over 8 weeks (or 12 for HZA106837). The cohort was the meta-analysis of a combination of 7 randomized, double-blind, placebo-controlled, parallel-group, multi center studies conducted in 26 countries. They included FFA109684, FFA109685, FFA109687, FFA112059, HZA106827, HZA106829, and HZA106837.	Allele A is not associated with response to corticosteroids in people with Asthma as compared to allele G.	27523435	1448258128
STIP1	rs3751122	T	corticosteroids	efficacy	no	The drugs were fluticasone furoate (82% of patients) and fluticasone propionate (18%). Response was assessed as change in FEV1 from baseline over 8 weeks (or 12 for HZA106837). The cohort was the meta-analysis of a combination of 7 randomized, double-blind, placebo-controlled, parallel-group, multi center studies conducted in 26 countries. They included FFA109684, FFA109685, FFA109687, FFA112059, HZA106827, HZA106829, and HZA106837.	Allele T is not associated with response to corticosteroids in people with Asthma as compared to allele G.	27523435	1448258035