PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
TRIM37	7	PNKP	3	two hybrid	Rual JF (2005)	1
RPA3	2	GEMIN4	2	affinity chromatography technology	Marechal A (2014)	1
RPA1	0	XRCC5	5	affinity chromatography technology	Marechal A (2014)	1
SUV39H1	0	KDM1A	2	two hybrid	Weimann M (2013)	1
NF2	1	7515	0	affinity chromatography technology	Zhou L (2015)	1
NTRK1	1	PNKP	3	affinity chromatography technology	Emdal KB (2015)	1
NF2	1	RPA2	0	affinity chromatography technology	Zhou L (2015)	1
PNKP	3	CDK11B	1	affinity chromatography technology	Koch CA (2004)	1
PNKP	3	LIG4	0	affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Koch CA (2004)	2
YWHAQ	0	PRKDC	12	affinity chromatography technology, pull down	Pozuelo-Rubio M (2010), Meek SE (2004)	2
TCOF1	1	NOLC1	2	affinity chromatography technology, affinity chromatography technology, genetic interference	Werner A (2015), Werner A (2015), Horlbeck MA (2018)	3
RPA3	2	RPA2	0	biochemical, x-ray crystallography, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Bochkareva E (1998), Bochkareva E (2002), Havugimana PC (2012), Du Y (2009), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	7
NF2	1	ATAD3B	5	affinity chromatography technology	Zhou L (2015)	1
NTRK1	1	7515	0	affinity chromatography technology	Emdal KB (2015)	1
EED	1	XRCC6	3	affinity chromatography technology	Cao Q (2014)	1
EED	1	SUPT16H	4	affinity chromatography technology	Cao Q (2014)	1
PNKP	3	NUP93	5	affinity chromatography technology	Ewing RM (2007)	1
XRCC4	0	LIG4	0	two hybrid, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Deshpande RA (2007), Deshpande RA (2007), Sibanda BL (2001), Drouet J (2005), Huang J (2002), Nick McElhinny SA (2000), Wang YG (2004), Wang YG (2004), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	11
TRIM25	5	PNKP	3	affinity chromatography technology	Choudhury NR (2017)	1
NTRK1	1	TCOF1	1	affinity chromatography technology	Emdal KB (2015)	1
RPA3	2	KDM1A	2	affinity chromatography technology	Marechal A (2014)	1
PARP1	3	XRCC5	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Ju BG (2006), Galande S (1999), Galande S (1999), Galande S (1999), Idogawa M (2007), Li B (2004), Li B (2004), Yin H (2006), Yin H (2006), Sand-Dejmek J (2011), Wu T (2013)	11
PNKP	3	MYOZ1	1	two hybrid	Rual JF (2005)	1
YWHAQ	0	LMNA	2	affinity chromatography technology, pull down	Pozuelo-Rubio M (2010), Meek SE (2004)	2
PRKDC	12	RPA2	0	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Shao RG (1999), Shao RG (1999), Shao RG (1999), Wu X (2006), Zernik-Kobak M (1997), Chan DW (2000), Marechal A (2014), Fried LM (1996)	8
RPA1	0	RPA2	0	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shao RG (1999), Bochkareva E (2002), Gong Z (2011), Havugimana PC (2012), Kristensen AR (2012), Ghospurkar PL (2014), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Elia AE (2015), Elia AE (2015), Huttlin EL (2017), Feeney L (2017)	13
PNKP	3	C18orf25	3	affinity chromatography technology	Koch CA (2004)	1
EED	1	PRKDC	12	affinity chromatography technology	Cao Q (2014)	1
LMNA	2	PRKDC	12	affinity chromatography technology	Liu GH (2011)	1
PNKP	3	HNRNPU	12	affinity chromatography technology	Koch CA (2004)	1
IKZF1	2	PNKP	3	two hybrid	Rolland T (2014)	1
RPA3	2	PNKP	3	affinity chromatography technology	Marechal A (2014)	1
PNKP	3	ATAD3B	5	affinity chromatography technology	Ewing RM (2007)	1
TRIM25	5	APP	1	affinity chromatography technology	Choudhury NR (2017)	1
YWHAQ	0	NOLC1	2	pull down	Meek SE (2004)	1
PNKP	3	PARP1	3	affinity chromatography technology	Koch CA (2004)	1
PNKP	3	MCM3	2	affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Koch CA (2004)	2
EED	1	HNRNPU	12	affinity chromatography technology	Cao Q (2014)	1
EED	1	7515	0	affinity chromatography technology	Cao Q (2014)	1
PNKP	3	MCM5	1	affinity chromatography technology	Koch CA (2004)	1
PNKP	3	SLC25A12	2	affinity chromatography technology	Ewing RM (2007)	1
RPA2	0	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Shao RG (1999), Shao RG (1999), Marechal A (2014), Wan C (2015)	4
POLB	0	LIG3	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TRIM25	5	PRKDC	12	affinity chromatography technology	Choudhury NR (2017)	1
NOLC1	2	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
EED	1	SSRP1	1	affinity chromatography technology	Cao Q (2014)	1
XRCC4	0	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Drouet J (2005), Drouet J (2005)	2
RPA1	0	KDM1A	2	affinity chromatography technology	Marechal A (2014)	1
NTRK1	1	MCM3	2	affinity chromatography technology	Emdal KB (2015)	1
PNKP	3	NOM1	2	affinity chromatography technology	Ewing RM (2007)	1
NF2	1	SLC25A12	2	affinity chromatography technology	Zhou L (2015)	1
PNKP	3	TCOF1	1	affinity chromatography technology	Koch CA (2004)	1
PRKDC	12	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, enzymatic study, affinity chromatography technology	Shao RG (1999), Drouet J (2005), Gottlieb TM (1993), Shamanna RA (2011), Shamanna RA (2011), Havugimana PC (2012), Sartorius CA (2000), Sartorius CA (2000), Hein MY (2015)	9
NTRK1	1	KDM1A	2	affinity chromatography technology	Emdal KB (2015)	1
PARP1	3	SUPT16H	4	enzymatic study	Huang JY (2006)	1
RPA2	0	SSRP1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NTRK1	1	PRKDC	12	affinity chromatography technology	Emdal KB (2015)	1
PARP1	3	7515	0	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gueven N (2004), Gueven N (2004), Masson M (1998), Masson M (1998), Cazzalini O (2010), Lee CH (2010), Leppard JB (2003)	7
NTRK1	1	MCM5	1	affinity chromatography technology	Emdal KB (2015)	1
PNKP	3	ZNF639	3	two hybrid	Rolland T (2014)	1
RPA3	2	XRCC6	3	affinity chromatography technology	Marechal A (2014)	1
RPA1	0	XRCC6	3	affinity chromatography technology	Marechal A (2014)	1
NTRK1	1	CDK11B	1	affinity chromatography technology	Emdal KB (2015)	1
MAGEA11	1	MYOZ1	1	two hybrid	Rual JF (2005)	1
RPA1	0	GEMIN4	2	affinity chromatography technology	Marechal A (2014)	1
PNKP	3	UBE2O	5	affinity chromatography technology	Koch CA (2004)	1
PRKDC	12	7515	0	affinity chromatography technology, affinity chromatography technology	Toulany M (2008), Toulany M (2008)	2
RPA1	0	7515	0	affinity chromatography technology, affinity chromatography technology	Marechal A (2014), Elia AE (2015)	2
LMNA	2	XRCC6	3	bioid	Roux KJ (2012)	1
RPA3	2	HNRNPU	12	affinity chromatography technology	Marechal A (2014)	1
NTRK1	1	RPA1	0	affinity chromatography technology	Emdal KB (2015)	1
SSRP1	1	SUPT16H	4	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Birch JL (2009), Tan BC (2006), Tan BC (2006), Pavri R (2006), Huang JY (2006), Huang JY (2006), OConnell BC (2010), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	12
HNRNPU	12	SUPT16H	4	affinity chromatography technology	Hein MY (2015)	1
TRIM25	5	UBE2O	5	affinity chromatography technology	Choudhury NR (2017)	1
PNKP	3	KDM1A	2	two hybrid	Weimann M (2013)	1
RPA2	0	SUPT16H	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PNKP	3	DCPS	1	biochemical	Wan C (2015)	1
RPA2	0	LIG3	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marechal A (2014), Huttlin EL (2015), Huttlin EL (2017)	3
LMNA	2	TRIM26	1	two hybrid	Dittmer TA (2014)	1
MYOZ1	1	APP	1	pull down	Olah J (2011)	1
NF2	1	DCAF1	5	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology	Huang J (2008), Huang J (2008), Huang J (2008), Huang J (2008), Huang J (2008), Li W (2010), Li W (2010), Li W (2010), Mori T (2014), Mori T (2014), Mori T (2014), Zhou L (2015), Laulajainen M (2011), Laulajainen M (2011)	14
RPA2	0	MCM5	1	two hybrid	Kneissl M (2003)	1
RPA3	2	PARP1	3	affinity chromatography technology	Marechal A (2014)	1
TRIM25	5	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
NTRK1	1	NASP	3	affinity chromatography technology	Emdal KB (2015)	1
GZMK	0	PNKP	3	two hybrid	Wang J (2011)	1
TRIM25	5	HNRNPU	12	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
TRIM25	5	RPA1	0	affinity chromatography technology	Pauli EK (2014)	1
RPA2	0	7515	0	affinity chromatography technology, affinity chromatography technology	Marechal A (2014), Huttlin EL (2017)	2
7515	0	PNKP	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Whitehouse CJ (2001), Ewing RM (2007), Ewing RM (2007), Whitehouse CJ (2001), Whitehouse CJ (2001), Whitehouse CJ (2001), Luo H (2004), Koch CA (2004), Hein MY (2015)	9
YWHAQ	0	FOXO3	1	affinity chromatography technology	Mahmud DL (2002)	1
RPA1	0	PNKP	3	affinity chromatography technology	Marechal A (2014)	1
PNKP	3	KRTAP4-12	2	two hybrid	Rual JF (2005)	1
LIG3	6	XRCC6	3	affinity chromatography technology, pull down, affinity chromatography technology	Leppard JB (2003), Leppard JB (2003), Huttlin EL (2017)	3
XRCC5	5	PRKDC	12	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, biochemical, affinity chromatography technology	Jin S (1997), Matheos D (2002), Gell D (1999), Drouet J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Olsen BB (2012), Olsen BB (2012), Sand-Dejmek J (2011), Sartorius CA (2000), Sartorius CA (2000), Drouet J (2006), Drouet J (2006), Sibanda BL (2010), Wan C (2015), Hein MY (2015)	17
PRKDC	12	LIG4	0	unspecified method, affinity chromatography technology, enzymatic study	Kim ST (1999), Wang YG (2004), Wang YG (2004)	3
PNKP	3	HBA2	0	affinity chromatography technology	Huttlin EL (2017)	1
NTRK1	1	LAS1L	3	affinity chromatography technology	Emdal KB (2015)	1
TRIM25	5	C18orf25	3	affinity chromatography technology	Choudhury NR (2017)	1
NTRK1	1	SUPT16H	4	affinity chromatography technology	Emdal KB (2015)	1
XRCC4	0	PRKDC	12	affinity chromatography technology, biochemical, affinity chromatography technology	Drouet J (2005), Havugimana PC (2012), Wang YG (2004)	3
PNKP	3	GEMIN4	2	affinity chromatography technology	Koch CA (2004)	1
XRCC6	3	SSRP1	1	affinity chromatography technology	Huttlin EL (2017)	1
POLB	0	SSRP1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RPA2	0	GEMIN4	2	affinity chromatography technology	Marechal A (2014)	1
TRIM25	5	TCOF1	1	affinity chromatography technology	Choudhury NR (2017)	1
RPA2	0	PNKP	3	affinity chromatography technology	Marechal A (2014)	1
PNKP	3	DCAF1	5	affinity chromatography technology	Koch CA (2004)	1
XRCC5	5	XRCC6	3	two hybrid, biochemical, two hybrid, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, enzymatic study, x-ray crystallography, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology	Gell D (1999), Barlev NA (1998), Yang CR (1999), Singleton BK (1999), Song K (2000), Gell D (1999), Gell D (1999), Willis DM (2002), Willis DM (2002), Drouet J (2005), Drouet J (2005), Cohen HY (2004), Lan L (2010), Cooper MP (2000), Cooper MP (2000), Velma V (2010), Zheng Y (2011), Sucharov CC (2004), Sucharov CC (2004), Sibani S (2005), Sibani S (2005), Walker JR (2001), Nick McElhinny SA (2000), Nick McElhinny SA (2000), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Pucci S (2009), Trougakos IP (2009), Havugimana PC (2012), Sartorius CA (2000), Sartorius CA (2000), Rivera-Calzada A (2007), Kelavkar UP (2001), Kelavkar UP (2001), Kristensen AR (2012), Kim E (2008), Wan C (2015), Hein MY (2015), Hein MY (2015), Nolens G (2009), Nolens G (2009), Nolens G (2009), Nolens G (2009), Huttlin EL (2017), Fantini D (2017)	46
RPA1	0	PARP1	3	affinity chromatography technology	Marechal A (2014)	1
POLB	0	SUPT16H	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RPA1	0	TCOF1	1	affinity chromatography technology	Marechal A (2014)	1
NOLC1	2	SSRP1	1	biochemical	Wan C (2015)	1
EED	1	LIG3	6	affinity chromatography technology	Cao Q (2014)	1
LIG3	6	PARP1	3	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	Leppard JB (2003), Leppard JB (2003), Leppard JB (2003), Leppard JB (2003)	4
NF2	1	SUPT16H	4	affinity chromatography technology	Zhou L (2015)	1
XRCC6	3	SUPT16H	4	affinity chromatography technology	Huttlin EL (2017)	1
RPA2	0	PARP1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marechal A (2014), Huttlin EL (2015), Huttlin EL (2017)	3
XRCC6	3	7515	0	affinity chromatography technology	Huttlin EL (2017)	1
PNKP	3	NASP	3	affinity chromatography technology	Koch CA (2004)	1
MCM3	2	MCM5	1	two hybrid, two hybrid, affinity chromatography technology, biochemical, pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), DaFonseca CJ (2001), Havugimana PC (2012), Ramachandran N (2004), Kristensen AR (2012), Wan C (2015), Drissi R (2015), Huttlin EL (2017), Chen YH (2015), Lossaint G (2013), Lossaint G (2013), Mulvaney KM (2016)	13
YWHAQ	0	MCM3	2	pull down	Meek SE (2004)	1
TRIM25	5	YWHAQ	0	affinity chromatography technology	Choudhury NR (2017)	1
LMNA	2	HNRNPU	12	affinity chromatography technology	Depreux FF (2015)	1
PNKP	3	NOL3	0	affinity chromatography technology	Ewing RM (2007)	1
NF2	1	LIG3	6	affinity chromatography technology	Zhou L (2015)	1
EED	1	LMNA	2	affinity chromatography technology	Cao Q (2014)	1
TRIM25	5	DDX20	4	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
NTRK1	1	GEMIN4	2	affinity chromatography technology	Emdal KB (2015)	1
MCM5	1	APP	1	pull down	Olah J (2011)	1
YWHAQ	0	PNKP	3	affinity chromatography technology	Ewing RM (2007)	1
EED	1	NOLC1	2	affinity chromatography technology	Cao Q (2014)	1
SSRP1	1	MCM3	2	affinity chromatography technology, affinity chromatography technology	Tan BC (2006), OConnell BC (2010)	2
XRCC6	3	LIG4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Drouet J (2005), Nick McElhinny SA (2000), Woods NT (2012), Hein MY (2015)	4
XRCC5	5	SSRP1	1	affinity chromatography technology, imaging technique	Sand-Dejmek J (2011), Sand-Dejmek J (2011)	2
NF2	1	SSRP1	1	affinity chromatography technology	Zhou L (2015)	1
NTRK1	1	NUP93	5	affinity chromatography technology	Emdal KB (2015)	1
7515	0	LIG3	6	two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Whitehouse CJ (2001), Ewing RM (2007), Caldecott KW (1994), Nash RA (1997), Dulic A (2001), Taylor RM (1998), Ogi T (2010), Hein MY (2015)	8
TRIM25	5	SUPT16H	4	affinity chromatography technology	Choudhury NR (2017)	1
EED	1	XRCC5	5	affinity chromatography technology	Cao Q (2014)	1
LMNA	2	SSRP1	1	affinity chromatography technology	Depreux FF (2015)	1
NTRK1	1	SSRP1	1	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	DDX20	4	affinity chromatography technology	Emdal KB (2015)	1
RPA2	0	MCM3	2	two hybrid, biochemical	Kneissl M (2003), Havugimana PC (2012)	2
RPA3	2	PRKDC	12	affinity chromatography technology	Marechal A (2014)	1
XRCC5	5	SUPT16H	4	affinity chromatography technology, affinity chromatography technology	Sand-Dejmek J (2011), Sand-Dejmek J (2011)	2
PARP1	3	POLB	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cazzalini O (2010), Cazzalini O (2010), Lee CH (2010), Huttlin EL (2015), Huttlin EL (2017)	5
LMNA	2	PNKP	3	two hybrid	Dittmer TA (2014)	1
PNKP	3	NOLC1	2	affinity chromatography technology	Koch CA (2004)	1
XRCC5	5	LIG4	0	affinity chromatography technology, affinity chromatography technology	Drouet J (2005), Nick McElhinny SA (2000)	2
PNKP	3	AGTPBP1	4	affinity chromatography technology	Koch CA (2004)	1
NTRK1	1	HNRNPU	12	affinity chromatography technology	Emdal KB (2015)	1
NF2	1	XRCC4	0	affinity chromatography technology	Zhou L (2015)	1
RPA1	0	LIG3	6	affinity chromatography technology, affinity chromatography technology	Marechal A (2014), Elia AE (2015)	2
PNKP	3	HBB	0	affinity chromatography technology	Huttlin EL (2017)	1
RPA1	0	HNRNPU	12	affinity chromatography technology	Marechal A (2014)	1
PRKDC	12	DCAF1	5	enzymatic study	Kim K (2012)	1
PNKP	3	SUPT16H	4	affinity chromatography technology	Koch CA (2004)	1
EED	1	NOM1	2	affinity chromatography technology	Cao Q (2014)	1
RPA2	0	HNRNPU	12	affinity chromatography technology	Marechal A (2014)	1
XRCC4	0	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Drouet J (2005), Drouet J (2005), Hein MY (2015)	3
TNIP1	1	PNKP	3	two hybrid	Rolland T (2014)	1
TRIM25	5	XRCC6	3	affinity chromatography technology	Choudhury NR (2017)	1
EED	1	KDM1A	2	affinity chromatography technology	Cao Q (2014)	1
PNKP	3	MID1	1	biochemical	Havugimana PC (2012)	1
PNKP	3	XRCC6	3	affinity chromatography technology	Koch CA (2004)	1
NTRK1	1	NOM1	2	affinity chromatography technology	Emdal KB (2015)	1
SSRP1	1	PARP1	3	affinity chromatography technology	Huttlin EL (2017)	1
NTRK1	1	XRCC5	5	affinity chromatography technology	Emdal KB (2015)	1
POLB	0	7515	0	two hybrid, pull down, pull down, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang L (2004), Fan J (2004), Kubota Y (1996), Kubota Y (1996), Bhattacharyya N (2001), Bhattacharyya N (2001), Luo H (2004), Huttlin EL (2015), Hein MY (2015), Fang Q (2014), Fang Q (2014), Huttlin EL (2017)	12
LMNA	2	RPA1	0	biochemical	Wan C (2015)	1
DDX20	4	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
PNKP	3	NRDC	3	affinity chromatography technology	Koch CA (2004)	1
PARP1	3	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Ju BG (2006), Galande S (1999), Galande S (1999), Galande S (1999), Idogawa M (2007), Li B (2004), Li B (2004), Yin H (2006), Yin H (2006), Wu T (2013), Huttlin EL (2017)	11
NTRK1	1	DNAAF5	4	affinity chromatography technology	Emdal KB (2015)	1
DDX20	4	MCM3	2	affinity chromatography technology	Boldt K (2016)	1
PNKP	3	DDX20	4	affinity chromatography technology	Ewing RM (2007)	1
PNKP	3	XRCC4	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Koch CA (2004), Koch CA (2004), Huttlin EL (2015), Huttlin EL (2017)	5
GEMIN4	2	DDX20	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Carnegie GK (2003), Charroux B (2000), Charroux B (2000), Mourelatos Z (2002), Joshi P (2013), Joshi P (2013), Huttlin EL (2017)	7
RPA3	2	7515	0	affinity chromatography technology	Marechal A (2014)	1
PARP1	3	PRKDC	12	affinity chromatography technology	Ju BG (2006)	1
ATXN3	2	XRCC6	3	affinity chromatography technology	Li Y (2007)	1
SSRP1	1	MCM5	1	affinity chromatography technology, affinity chromatography technology	Tan BC (2006), OConnell BC (2010)	2
SUV39H1	0	SMAD5	2	affinity chromatography technology	Frontelo P (2004)	1
NTRK1	1	UBE2O	5	affinity chromatography technology	Emdal KB (2015)	1
NF2	1	KDM1A	2	two hybrid	Weimann M (2013)	1
PNKP	3	ATXN3	2	protein complementation assay, imaging technique	Gao R (2015), Gao R (2015)	2
RPA3	2	RPA1	0	biochemical, x-ray crystallography, affinity chromatography technology, biochemical, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology	Bochkareva E (1998), Bochkareva E (2002), Gong Z (2011), Havugimana PC (2012), Du Y (2009), Wan C (2015), Hein MY (2015), Elia AE (2015)	8
NTRK1	1	PARP1	3	affinity chromatography technology	Emdal KB (2015)	1
LIG3	6	APP	1	pull down	Olah J (2011)	1
PNKP	3	PRKDC	12	affinity chromatography technology	Koch CA (2004)	1
PNKP	3	XRCC5	5	affinity chromatography technology	Koch CA (2004)	1
POLB	0	PNKP	3	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Whitehouse CJ (2001), Whitehouse CJ (2001), Whitehouse CJ (2001), Huttlin EL (2015), Huttlin EL (2017)	5
FOXO3	1	PNKP	3	affinity chromatography technology	Li X (2015)	1
YWHAQ	0	DCPS	1	pull down	Meek SE (2004)	1
NTRK1	1	DCPS	1	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	NRDC	3	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	ATAD3B	5	affinity chromatography technology	Emdal KB (2015)	1
RPA3	2	TCOF1	1	affinity chromatography technology, genetic interference	Marechal A (2014), Horlbeck MA (2018)	2
LMNA	2	PARP1	3	bioid, affinity chromatography technology	Roux KJ (2012), Depreux FF (2015)	2
EED	1	NUP93	5	affinity chromatography technology	Cao Q (2014)	1
NTRK1	1	YWHAQ	0	affinity chromatography technology	Emdal KB (2015)	1
HNRNPU	12	MCM5	1	biochemical, affinity chromatography technology	Havugimana PC (2012), Drissi R (2015)	2
ATXN3	2	APP	1	pull down	Olah J (2011)	1
NF2	1	PARP1	3	affinity chromatography technology	Zhou L (2015)	1
NTRK1	1	LMNA	2	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	XRCC6	3	affinity chromatography technology	Emdal KB (2015)	1
PNKP	3	LAS1L	3	affinity chromatography technology	Ewing RM (2007)	1
NTRK1	1	LIG3	6	affinity chromatography technology	Emdal KB (2015)	1
PRKDC	12	RPA1	0	pull down, affinity chromatography technology, affinity chromatography technology	Shao RG (1999), Gong Z (2011), Marechal A (2014)	3
NF2	1	XRCC5	5	affinity chromatography technology	Zhou L (2015)	1
RPA2	0	KDM1A	2	affinity chromatography technology	Marechal A (2014)	1
PNKP	3	DNAAF5	4	affinity chromatography technology	Ewing RM (2007)	1
MAGEA11	1	PNKP	3	two hybrid	Rual JF (2005)	1
RPA1	0	MCM3	2	affinity chromatography technology	Gong Z (2011)	1
PNKP	3	SSRP1	1	affinity chromatography technology	Koch CA (2004)	1
GZMK	0	LIG4	0	two hybrid	Wang J (2011)	1
NF2	1	XRCC6	3	affinity chromatography technology	Zhou L (2015)	1
NF2	1	RPA1	0	affinity chromatography technology	Zhou L (2015)	1
PNKP	3	LIG3	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Ewing RM (2007), Whitehouse CJ (2001), Whitehouse CJ (2001), Whitehouse CJ (2001)	4
RPA3	2	LIG3	6	affinity chromatography technology	Marechal A (2014)	1
RPA2	0	TCOF1	1	affinity chromatography technology	Marechal A (2014)	1
TRIM25	5	LMNA	2	affinity chromatography technology	Choudhury NR (2017)	1
SMAD5	2	PNKP	3	two hybrid	Colland F (2004)	1
RPA2	0	APP	1	pull down	Olah J (2011)	1
EED	1	PNKP	3	affinity chromatography technology	Cao Q (2014)	1
CCDC43	0	PNKP	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PNKP	3	SUV39H1	0	two hybrid	Weimann M (2013)	1
EED	1	TCOF1	1	affinity chromatography technology	Cao Q (2014)	1
RPA3	2	XRCC5	5	affinity chromatography technology	Marechal A (2014)	1
YWHAQ	0	CDK11B	1	affinity chromatography technology, pull down	Feng Y (2005), Feng Y (2005)	2
PNKP	3	SBDS	5	biochemical	Wan C (2015)	1
LIG3	6	XRCC5	5	affinity chromatography technology, pull down	Leppard JB (2003), Leppard JB (2003)	2
ZBTB14	2	PNKP	3	two hybrid	Rolland T (2014)	1
LMNA	2	SBDS	5	two hybrid	Dittmer TA (2014)	1
RPA2	0	XRCC5	5	affinity chromatography technology	Marechal A (2014)	1
NF2	1	PNKP	3	affinity chromatography technology	Zhou L (2015)	1
PNKP	3	TRIM26	1	affinity chromatography technology	Koch CA (2004)	1
PNKP	3	APP	1	pull down	Olah J (2011)	1
SUPT16H	4	RPA3	2	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	DCAF1	5	affinity chromatography technology	Emdal KB (2015)	1
MCM5	1	LMNA	2	affinity chromatography technology, two hybrid	Drissi R (2015), Dittmer TA (2014)	2