Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
CHRM5 1133 METHIXENE CHEMBL1201342 antagonist TdgClinicalTrial, TEND, DrugBank 11752352, 17139284, 17016423
CHRM5 1133 LOXAPINE CHEMBL831 binder DrugBank
CHRM5 1133 CHLORPROTHIXENE CHEMBL908 antagonist DrugBank 7855217
CHRM5 1133 ACLIDINIUM CHEMBL1194325 antagonist TdgClinicalTrial, DrugBank
CHRM5 1133 UMECLIDINIUM CHEMBL1187833 antagonist GuideToPharmacologyInteractions, DrugBank 23435542
CHRM5 1133 CHEMBL343357 CHEMBL343357 allosteric modulator GuideToPharmacologyInteractions
CHRM5 1133 CHEMBL139677 CHEMBL139677 allosteric modulator GuideToPharmacologyInteractions
CHRM5 1133 CHEMBL466253 CHEMBL466253 allosteric modulator GuideToPharmacologyInteractions
CHRM5 1133 4-DAMP CHEMBL76897 antagonist GuideToPharmacologyInteractions
CHRM5 1133 DOTHIEPIN (CHEMBL1492500) CHEMBL1492500 antagonist GuideToPharmacologyInteractions
CHRM5 1133 GLYCOPYRROLATE CHEMBL1201335 antagonist GuideToPharmacologyInteractions
CHRM5 1133 METHOCTRAMINE CHEMBL27673 antagonist GuideToPharmacologyInteractions
CHRM5 1133 PIRENZEPINE CHEMBL9967 antagonist GuideToPharmacologyInteractions
CHRM5 1133 CHEMBL1233686 CHEMBL1233686 antagonist GuideToPharmacologyInteractions
CHRM5 1133 CHEMBL1628667 CHEMBL1628667 antagonist GuideToPharmacologyInteractions
CHRM5 1133 DOXEPIN CHEMBL1628227 TdgClinicalTrial
CHRM5 1133 TERFENADINE CHEMBL17157 binder DrugBank 10212017
CHRM5 1133 DARIFENACIN CHEMBL1346 antagonist GuideToPharmacologyInteractions, DrugBank 18046909, 10374898
CHRM5 1133 LEVOMEPROMAZINE CHEMBL1764 antagonist TdgClinicalTrial, TEND, DrugBank 2870716, 2899826
CHRM5 1133 ERIBAXABAN CHEMBL476186 agonist GuideToPharmacologyInteractions
CHRM5 1133 SABCOMELINE CHEMBL134641 agonist GuideToPharmacologyInteractions
CHRM5 1133 STRYCHNINE CHEMBL227934 allosteric modulator GuideToPharmacologyInteractions
CHRM5 1133 AMITRIPTYLINE CHEMBL629 antagonist GuideToPharmacologyInteractions
CHRM5 1133 BENZTROPINE MESYLATE CHEMBL1200383 antagonist GuideToPharmacologyInteractions
CHRM5 1133 HIMBACINE CHEMBL277642 antagonist GuideToPharmacologyInteractions
CHRM5 1133 CHEMBL1256682 CHEMBL1256682 antagonist GuideToPharmacologyInteractions
CHRM5 1133 OTENZEPAD CHEMBL17045 antagonist GuideToPharmacologyInteractions
CHRM5 1133 OXYBUTYNIN CHEMBL1231 antagonist GuideToPharmacologyInteractions
CHRM5 1133 SOLIFENACIN CHEMBL1734 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions
CHRM5 1133 DAROTROPIUM BROMIDE CHEMBL2103803 antagonist ChemblInteractions
CHRM5 1133 THIETHYLPERAZINE CHEMBL1378 TdgClinicalTrial, TEND
CHRM5 1133 OLANZAPINE CHEMBL715 antagonist TdgClinicalTrial, TEND, DrugBank 10227113, 17848919
CHRM5 1133 PROMAZINE CHEMBL564 antagonist, binder TdgClinicalTrial, TEND, DrugBank, TTD 11752352, 17139284, 17016423
CHRM5 1133 PROPIOMAZINE CHEMBL1201210 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423
CHRM5 1133 BROMPHENIRAMINE CHEMBL811 antagonist DrugBank 10212017
CHRM5 1133 TOLTERODINE CHEMBL1382 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, DrugBank 16406943
CHRM5 1133 CHEMBL99521 CHEMBL99521 agonist GuideToPharmacologyInteractions
CHRM5 1133 CHEMBL74300 CHEMBL74300 agonist GuideToPharmacologyInteractions
CHRM5 1133 MILAMELINE CHEMBL151938 agonist GuideToPharmacologyInteractions
CHRM5 1133 PILOCARPINE CHEMBL550 agonist GuideToPharmacologyInteractions
CHRM5 1133 XANOMELINE CHEMBL21536 agonist GuideToPharmacologyInteractions
CHRM5 1133 BRUCINE CHEMBL501756 allosteric modulator GuideToPharmacologyInteractions
CHRM5 1133 CHEMBL3105228 CHEMBL3105228 allosteric modulator GuideToPharmacologyInteractions
CHRM5 1133 ATROPINE CHEMBL517712 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, TEND, TTD
CHRM5 1133 HEXOCYCLIUM CHEMBL1201325 antagonist GuideToPharmacologyInteractions
CHRM5 1133 TRIPITRAMINE CHEMBL265256 antagonist GuideToPharmacologyInteractions
CHRM5 1133 Afacifenacin CHEMBL3545165 antagonist ChemblInteractions
CHRM5 1133 PROMETHAZINE CHEMBL643 TdgClinicalTrial, TEND
CHRM5 1133 CLOZAPINE CHEMBL42 antagonist DrugBank 17848919
CHRM5 1133 BENZQUINAMIDE CHEMBL1201250 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423
CHRM5 1133 ARIPIPRAZOLE CHEMBL1112 antagonist DrugBank 17848919
CHRM5 1133 FESOTERODINE CHEMBL1201764 antagonist DrugBank 19029429
CHRM5 1133 ACETYLCHOLINE CHEMBL667 agonist GuideToPharmacologyInteractions
CHRM5 1133 CHEMBL343796 CHEMBL343796 allosteric modulator GuideToPharmacologyInteractions
CHRM5 1133 CHEMBL523685 CHEMBL523685 allosteric modulator GuideToPharmacologyInteractions
CHRM5 1133 CHEMBL279453 CHEMBL279453 antagonist GuideToPharmacologyInteractions
CHRM5 1133 BIPERIDEN (CHEMBL1101) CHEMBL1101 antagonist GuideToPharmacologyInteractions
CHRM5 1133 CHEMBL580785 CHEMBL580785 antagonist GuideToPharmacologyInteractions
CHRM5 1133 IPRATROPIUM CHEMBL1621597 antagonist GuideToPharmacologyInteractions
CHRM5 1133 HYDROCHLORIC ACID CHEMBL1231821 antagonist GuideToPharmacologyInteractions
CHRM5 1133 COENZYME_A CHEMBL1213327 antagonist GuideToPharmacologyInteractions
CHRM5 1133 QUINUCLIDINYL BENZILATE CHEMBL12980 antagonist GuideToPharmacologyInteractions
CHRM5 1133 HOMATROPINE METHYLBROMIDE CHEMBL1200851 TdgClinicalTrial, TEND
CHRM5 1133 SCOPOLAMINE CHEMBL1187846 antagonist DrugBank 18045203

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID