Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
ADORA3 140 AMINOPHYLLINE CHEMBL1370561 antagonist ChemblInteractions, DrugBank 9806324
ADORA3 140 ADENOSINE CHEMBL477 agonist GuideToPharmacologyInteractions, ChemblInteractions, TTD
ADORA3 140 CHEMBL175543 CHEMBL175543 agonist GuideToPharmacologyInteractions, TTD
ADORA3 140 CHEMBL2064657 CHEMBL2064657 agonist GuideToPharmacologyInteractions
ADORA3 140 GRAPIPRANT CHEMBL3039498 agonist GuideToPharmacologyInteractions
ADORA3 140 REGADENOSON CHEMBL317052 agonist GuideToPharmacologyInteractions
ADORA3 140 CGS-21680 CHEMBL331372 agonist GuideToPharmacologyInteractions
ADORA3 140 GS 6201 CHEMBL260933 antagonist GuideToPharmacologyInteractions
ADORA3 140 GALANGIN CHEMBL309490 antagonist GuideToPharmacologyInteractions
ADORA3 140 ISTRADEFYLLINE CHEMBL431770 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL2181965 CHEMBL2181965 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL375293 CHEMBL375293 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL76273 CHEMBL76273 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL449090 CHEMBL449090 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL340868 CHEMBL340868 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL89852 CHEMBL89852 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL322524 CHEMBL322524 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL111545 CHEMBL111545 antagonist GuideToPharmacologyInteractions
ADORA3 140 NICARDIPINE CHEMBL1484 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL8565 CHEMBL8565 antagonist GuideToPharmacologyInteractions
ADORA3 140 ROLOFYLLINE (CHEMBL2103819) CHEMBL2103819 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL118044 CHEMBL118044 antagonist GuideToPharmacologyInteractions
ADORA3 140 TONAPOFYLLINE CHEMBL414157 antagonist GuideToPharmacologyInteractions
ADORA3 140 THEOPHYLLINE SODIUM GLYCINATE CHEMBL1200578 antagonist ChemblInteractions
ADORA3 140 CHEMBL260563 CHEMBL260563 agonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL257833 CHEMBL257833 agonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL302765 CHEMBL302765 agonist, antagonist GuideToPharmacologyInteractions
ADORA3 140 NECA CHEMBL464859 agonist GuideToPharmacologyInteractions
ADORA3 140 (R)-PIA CHEMBL139000 agonist GuideToPharmacologyInteractions
ADORA3 140 (S)-PIA CHEMBL420705 agonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL475346 CHEMBL475346 allosteric modulator GuideToPharmacologyInteractions
ADORA3 140 FLAVONE CHEMBL275638 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL89093 CHEMBL89093 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL88147 CHEMBL88147 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL108705 CHEMBL108705 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL273807 CHEMBL273807 antagonist GuideToPharmacologyInteractions
ADORA3 140 SAKURANETIN CHEMBL448297 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL136689 CHEMBL136689 antagonist GuideToPharmacologyInteractions
ADORA3 140 VIPADENANT CHEMBL447664 antagonist GuideToPharmacologyInteractions
ADORA3 140 VISNAGIN CHEMBL45176 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL71053 CHEMBL71053 antagonist GuideToPharmacologyInteractions
ADORA3 140 IB-MECA CHEMBL119709 agonist TdgClinicalTrial, ChemblInteractions, DrugBank, TTD
ADORA3 140 OXTRIPHYLLINE CHEMBL1200434 antagonist ChemblInteractions
ADORA3 140 QAF805 CHEMBL3545204 antagonist ChemblInteractions
ADORA3 140 CF102 CHEMBL431733 agonist TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, TTD
ADORA3 140 CHEMBL574602 CHEMBL574602 agonist GuideToPharmacologyInteractions
ADORA3 140 APADENOSON CHEMBL1950649 agonist GuideToPharmacologyInteractions
ADORA3 140 BINODENOSON CHEMBL1950554 agonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL410873 CHEMBL410873 agonist GuideToPharmacologyInteractions
ADORA3 140 N6-CYCLOPENTYLADENOSINE CHEMBL68738 agonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL16997 CHEMBL16997 antagonist GuideToPharmacologyInteractions
ADORA3 140 CGS-15943 CHEMBL16687 antagonist GuideToPharmacologyInteractions
ADORA3 140 Derenofylline CHEMBL592435 antagonist GuideToPharmacologyInteractions
ADORA3 140 FK453 CHEMBL440115 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL355370 CHEMBL355370 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL219160 CHEMBL219160 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL72862 CHEMBL72862 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL317382 CHEMBL317382 antagonist GuideToPharmacologyInteractions
ADORA3 140 XANTHINE AMINE CONGENER CHEMBL273094 antagonist GuideToPharmacologyInteractions
ADORA3 140 ZM-241385 CHEMBL113142 antagonist GuideToPharmacologyInteractions
ADORA3 140 CAFFEINE CHEMBL113 antagonist GuideToPharmacologyInteractions, ChemblInteractions
ADORA3 140 THEOPHYLLINE CHEMBL190 antagonist GuideToPharmacologyInteractions, ChemblInteractions
ADORA3 140 CHEMBL472925 CHEMBL472925 agonist, allosteric modulator GuideToPharmacologyInteractions, TTD
ADORA3 140 CAFFEINE, CITRATED CHEMBL1200569 antagonist ChemblInteractions
ADORA3 140 CHEMBL1895774 CHEMBL1895774 agonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL609245 CHEMBL609245 agonist GuideToPharmacologyInteractions
ADORA3 140 DEXNIGULDIPINE CHEMBL2051956 antagonist GuideToPharmacologyInteractions
ADORA3 140 1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE [DPCPX] CHEMBL183 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL309566 CHEMBL309566 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL329722 CHEMBL329722 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL321845 CHEMBL321845 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL75772 CHEMBL75772 antagonist GuideToPharmacologyInteractions
ADORA3 140 PRELADENANT CHEMBL240624 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL1562432 CHEMBL1562432 antagonist GuideToPharmacologyInteractions
ADORA3 140 IMISOPASEM MANGANESE CHEMBL3544979 antagonist GuideToPharmacologyInteractions
ADORA3 140 ST1535 CHEMBL197669 antagonist GuideToPharmacologyInteractions
ADORA3 140 CHEMBL130499 CHEMBL130499 antagonist GuideToPharmacologyInteractions
ADORA3 140 ENPROFYLLINE CHEMBL279898 DrugBank 10496952

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
ADORA3 rs2298191 C methotrexate toxicity no Discontinuation due to adverse effects. Allele C is not associated with discontinuation of methotrexate in people with Arthritis, Rheumatoid as compared to allele T. 27217051 1449164906
ADORA3 rs1544223 C methotrexate toxicity no Discontinuation due to adverse effects. Please note that alleles have been complemented to the plus chromosomal strand. Allele C is not associated with discontinuation of methotrexate in people with Arthritis, Rheumatoid as compared to allele T. 27217051 1449164924
ADORA3 rs35511654 G methotrexate toxicity no Discontinuation due to adverse effects. Allele G is not associated with discontinuation of methotrexate in people with Arthritis, Rheumatoid as compared to allele T. 27217051 1449164918
ADORA3 rs3394 C methotrexate toxicity no Discontinuation due to adverse effects. Allele C is not associated with discontinuation of methotrexate in people with Arthritis, Rheumatoid as compared to allele T. 27217051 1449164880
ADORA3 rs3393 C methotrexate toxicity no Discontinuation due to adverse effects. Please note that alleles have been complemented to the plus chromosomal strand. Allele C is not associated with discontinuation of methotrexate in people with Arthritis, Rheumatoid as compared to allele T. 27217051 1449164912