PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
ZBP1	2	CTBP1	2	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
CTBP2	7	ZBTB18	9	two hybrid	Rolland T (2014)	1
DDX19B	2	TRIM25	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CTBP1	2	IKZF2	3	two hybrid	Corominas R (2014)	1
CTBP2	7	NRIP1	4	two hybrid, pull down	Rual JF (2005), Castet A (2004)	2
UBE2I	0	EP300	36	enzymatic study, affinity chromatography technology	Girdwood D (2003), Bian XL (2017)	2
CWC22	3	MED23	3	genetic interference	Horlbeck MA (2018)	1
KAT2B	2	KLF8	0	affinity chromatography technology	Urvalek AM (2010)	1
HNRNPL	3	APP	1	affinity chromatography technology	Fei T (2017)	1
BCL3	2	CTBP1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Keutgens A (2010), Keutgens A (2010), Choi HJ (2010), Choi HJ (2010), Choi HJ (2010), Choi HJ (2010)	6
HNRNPL	3	EP300	36	affinity chromatography technology	Fei T (2017)	1
EHMT2	4	HDAC2	1	affinity chromatography technology, affinity chromatography technology	Bantscheff M (2011), Bantscheff M (2011)	2
CTBP2	7	MDM2	2	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Mirnezami AH (2003), Mirnezami AH (2003), Birts CN (2011), Birts CN (2011)	4
DYRK1B	1	STUB1	4	affinity chromatography technology	Varjosalo M (2013)	1
CTBP2	7	STUB1	4	affinity chromatography technology, protein complementation assay	Lee JS (2013), Lee JS (2013)	2
UHRF2	1	RCOR1	0	affinity chromatography technology	Lai M (2016)	1
MDM2	2	KAT2B	2	pull down, affinity chromatography technology, genetic interference, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Jin Y (2002), Jin Y (2002), Jin Y (2002), Jin Y (2004), Jin Y (2004), Jung CR (2010), Morgan JE (2017)	7
FHL3	0	KLF3	0	two hybrid, pull down, affinity chromatography technology, two hybrid	Turner J (2003), Turner J (2003), Turner J (2003), Rolland T (2014)	4
SGTA	1	CTBP2	7	biochemical	Kristensen AR (2012)	1
CTBP2	7	RPS29	0	two hybrid	Wang J (2011)	1
ECT2	2	XRCC6	3	affinity chromatography technology	Woods NT (2012)	1
EGLN3	0	CDKN2A	1	affinity chromatography technology	Rodriguez J (2016)	1
EHMT2	4	CTBP1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ueda J (2006), Kuppuswamy M (2008), Huttlin EL (2015), Huttlin EL (2017)	4
CTBP2	7	UBC	7	two hybrid	Paliwal S (2006)	1
EHMT2	4	KLF3	0	two hybrid	Rolland T (2014)	1
CTBP2	7	HELZ	6	affinity chromatography technology	Boldt K (2016)	1
HNRNPL	3	EHMT1	18	affinity chromatography technology	Fei T (2017)	1
CTBP2	7	CWC22	3	affinity chromatography technology	Hein MY (2015)	1
FOXS1	2	CTBP2	7	affinity chromatography technology	Li X (2015)	1
CTBP2	7	CTBP2	7	two hybrid, affinity chromatography technology	Sewalt RG (1999), Zhao LJ (2009)	2
ZBP1	2	CTBP2	7	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
CTBP1	2	PLCB1	0	two hybrid	Rolland T (2014)	1
MDM2	2	EHMT1	18	affinity chromatography technology	Chen L (2010)	1
CTBP2	7	RAI2	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
CDKN2A	1	CTBP2	7	affinity chromatography technology, two hybrid, two hybrid	Paliwal S (2006), Paliwal S (2006), Paliwal S (2006)	3
HNRNPL	3	NRIP1	4	affinity chromatography technology	Fei T (2017)	1
CTBP2	7	MARF1	8	affinity chromatography technology	Boldt K (2016)	1
BCL3	2	RCOR1	0	affinity chromatography technology	Keutgens A (2010)	1
CTBP2	7	CTPS2	0	two hybrid	Wang J (2011)	1
UHRF2	1	UBE2I	0	affinity chromatography technology	Oh Y (2013)	1
TRIM25	5	RPL17	0	affinity chromatography technology	Choudhury NR (2017)	1
EHMT2	4	KAT2B	2	affinity chromatography technology, affinity chromatography technology	Oh ST (2014), Oh ST (2014)	2
ECT2	2	CTBP2	7	affinity chromatography technology	Woods NT (2012)	1
FOXQ1	0	CTBP2	7	affinity chromatography technology	Li X (2015)	1
FOXP1	23	FOXP2	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li S (2004), Li X (2015), Li X (2015), Huttlin EL (2017)	4
TRIM25	5	MVD	2	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	KLF3	0	affinity chromatography technology	Choudhury NR (2017)	1
CTBP1	2	FOXP2	13	affinity chromatography technology, two hybrid, two hybrid, two hybrid	Li S (2004), Li S (2004), Corominas R (2014), Rolland T (2014)	4
TRIM25	5	SGTA	1	affinity chromatography technology	Choudhury NR (2017)	1
EGLN3	0	RBM4	1	affinity chromatography technology	Rodriguez J (2016)	1
TRIM25	5	APP	1	affinity chromatography technology	Choudhury NR (2017)	1
CTBP2	7	RPS28	0	two hybrid	Wang J (2011)	1
EGLN3	0	PSMF1	0	affinity chromatography technology	Rodriguez J (2016)	1
IGFBP1	0	CTBP1	2	affinity chromatography technology	Huttlin EL (2017)	1
CDKN2A	1	KAT2B	2	affinity chromatography technology	Fei HJ (2017)	1
MDM2	2	UBC	7	pull down, enzymatic study, enzymatic study	Higashitsuji H (2005), Luo J (2013), Poyurovsky MV (2007)	3
UBC	7	STUB1	4	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Connell P (2001), Connell P (2001), Windheim M (2008), Zhang M (2005)	4
CTBP2	7	PSMF1	0	two hybrid	Rual JF (2005)	1
EP300	36	UBC	7	enzymatic study, affinity chromatography technology	Delvecchio M (2013), Kirilyuk A (2012)	2
CTBP1	2	RBBP8	1	pull down, affinity chromatography technology, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Li S (1999), Li S (1999), Schaeper U (1998), Schaeper U (1998), Schaeper U (1998), Schaeper U (1998), Schaeper U (1998), Oswald F (2005), Broderick R (2016)	9
EGLN3	0	ZFPM2	4	affinity chromatography technology	Rodriguez J (2016)	1
TRIM25	5	RPS4X	0	affinity chromatography technology	Choudhury NR (2017)	1
UBE2I	0	APP	1	enzymatic study	Gocke CB (2005)	1
CTBP2	7	FUNDC1	0	two hybrid	Rolland T (2014)	1
EHMT2	4	EHMT1	18	affinity chromatography technology, affinity chromatography technology	Bantscheff M (2011), Hauri S (2016)	2
ZNF217	3	EHMT2	4	affinity chromatography technology	Banck MS (2009)	1
CTBP2	7	ZNF750	4	two hybrid	Rolland T (2014)	1
CTBP1	2	UBE2I	0	affinity chromatography technology	Kuppuswamy M (2008)	1
SOX2	4	HDAC2	1	affinity chromatography technology	Engelen E (2011)	1
CTBP2	7	RBM26	3	affinity chromatography technology	Hein MY (2015)	1
TRIM25	5	EP300	36	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
CTBP2	7	RCOR1	0	affinity chromatography technology	Zhao LJ (2009)	1
DDX19B	2	CTBP2	7	biochemical	Kristensen AR (2012)	1
EHMT1	18	HIST3H3	0	enzymatic study	Shi Y (2003)	1
TRIM25	5	CTBP1	2	affinity chromatography technology	Choudhury NR (2017)	1
EHMT2	4	WIZ	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ueda J (2006), Ueda J (2006), Bantscheff M (2011), Hein MY (2015), Hauri S (2016)	5
CTBP2	7	ZEB1	3	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology	Postigo AA (1999), Zhao LJ (2009), Furusawa T (1999), Furusawa T (1999), Zhang P (2014)	5
EP300	36	KLF8	0	affinity chromatography technology	Urvalek AM (2010)	1
HDAC2	1	NRIP1	4	pull down	Castet A (2004)	1
EHMT2	4	HIST3H3	0	enzymatic study	Shi Y (2003)	1
ATXN1L	0	CTBP2	7	two hybrid, affinity chromatography technology	Lim J (2006), Lim J (2006)	2
HDAC2	1	EHMT1	18	affinity chromatography technology	Bantscheff M (2011)	1
STX11	1	APP	1	pull down	Olah J (2011)	1
UBE2I	0	CDKN2A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Rizos H (2005), Wang S (2015), Ivanschitz L (2015), Ivanschitz L (2015), Ivanschitz L (2015)	5
CTBP1	2	NOL4L	4	two hybrid, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Corominas R (2014), Rolland T (2014), Huttlin EL (2015), Yu H (2011), Huttlin EL (2017)	5
UBC	7	HNRNPL	3	affinity chromatography technology	Matsumoto M (2005)	1
MDM2	2	CTBP1	2	far western blotting, affinity chromatography technology	Mirnezami AH (2003), Mirnezami AH (2003)	2
KAT2B	2	HIST3H3	0	enzymatic study, enzymatic study	Seo SB (2001), Yang XJ (1996)	2
EP300	36	KAT2B	2	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Kim JH (2011), Lee M (2010), Santos-Rosa H (2003), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996), Mizuguchi Y (2012)	8
RPL17	0	RPL7A	1	biochemical	Havugimana PC (2012)	1
IGFBP1	0	CTBP2	7	affinity chromatography technology	Huttlin EL (2017)	1
RAI2	0	APP	1	pull down	Olah J (2011)	1
KLF8	0	CTBP1	2	affinity chromatography technology, affinity chromatography technology	Urvalek AM (2011), Urvalek AM (2011)	2
CTBP2	7	DMRTB1	1	two hybrid	Rolland T (2014)	1
DYRK1B	1	CDKN2A	1	affinity chromatography technology	Varjosalo M (2013)	1
SOX2	4	RBM4	1	affinity chromatography technology	Cox JL (2013)	1
CDC25C	0	CTBP2	7	affinity chromatography technology	Li X (2016)	1
HNRNPL	3	FOXP1	23	affinity chromatography technology	Fei T (2017)	1
CTBP2	7	EHMT2	4	affinity chromatography technology, affinity chromatography technology	Zhao LJ (2009), Ueda J (2006)	2
TRIM25	5	MARK3	2	affinity chromatography technology	Choudhury NR (2017)	1
CFTR	5	CTPS1	2	affinity chromatography technology	Pankow S (2015)	1
CTBP1	2	ZEB1	3	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Postigo AA (1999), Kuppuswamy M (2008), Furusawa T (1999), Furusawa T (1999), Zhang P (2014), Huttlin EL (2015), Huttlin EL (2017)	7
CBX4	1	CTBP1	2	pull down, enzymatic study, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xia ZB (2003), Kagey MH (2003), Dahiya A (2001), Sewalt RG (1999), Merrill JC (2010), Huttlin EL (2015), Huttlin EL (2017)	7
CTBP1	2	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Koipally J (2000), Glasspool RM (2005), Kuppuswamy M (2008), Kuppuswamy M (2008), Mendez LM (2008)	5
NRIP1	4	CTBP1	2	pull down, affinity chromatography technology, imaging technique, two hybrid	Castet A (2004), Perissi V (2008), Kiskinis E (2007), Corominas R (2014)	4
EHMT2	4	MED23	3	affinity chromatography technology	Ding N (2008)	1
WIZ	2	CTBP1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ueda J (2006), Kuppuswamy M (2008), Huttlin EL (2015), Huttlin EL (2017)	4
MED23	3	CTBP1	2	affinity chromatography technology	Lambert JP (2015)	1
ZFPM2	4	HDAC2	1	affinity chromatography technology	Roche AE (2008)	1
HNRNPL	3	SGTA	1	affinity chromatography technology	Fei T (2017)	1
ZBTB18	9	ATXN1L	0	affinity chromatography technology	Huttlin EL (2017)	1
CTBP2	7	PPP1R15A	2	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
CTBP2	7	STX11	1	two hybrid	Wang J (2011)	1
MARK3	2	CDC25C	0	enzymatic study, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study	Goeransson O (2006), Mueller J (2003), Peng CY (1998), Peng CY (1998), Peng CY (1998), Bachmann M (2004)	6
DYRK1B	1	EP300	36	affinity chromatography technology	Varjosalo M (2013)	1
TRIM25	5	RCOR1	0	affinity chromatography technology	Choudhury NR (2017)	1
HNRNPL	3	EGFR	5	affinity chromatography technology	Fei T (2017)	1
CTBP2	7	IKZF1	2	two hybrid, two hybrid, affinity chromatography technology	Rolland T (2014), Yu H (2011), Huttlin EL (2017)	3
CTBP2	7	IKZF2	3	two hybrid	Rolland T (2014)	1
FHL3	0	ZNF512B	2	two hybrid, affinity chromatography technology, affinity chromatography technology	Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	3
RPS28	0	RPS4X	0	biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012)	2
TRIM25	5	STUB1	4	affinity chromatography technology	Choudhury NR (2017)	1
FOXB1	1	CTBP2	7	affinity chromatography technology	Li X (2015)	1
SOX2	4	BAZ2B	15	affinity chromatography technology	Cox JL (2013)	1
CASP8AP2	3	CTBP2	7	two hybrid	Wang J (2011)	1
CTBP2	7	LCOR	4	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Fernandes I (2003), Rolland T (2014), Huttlin EL (2017), Hauri S (2016)	4
SMAD6	9	CTBP1	2	affinity chromatography technology, affinity chromatography technology	Lin X (2003), Herhaus L (2014)	2
CTBP2	7	ZFPM1	8	two hybrid	Wang J (2011)	1
RPL17	0	RPS4X	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
C15orf39	0	CTBP2	7	two hybrid	Wang J (2011)	1
CTBP2	7	CTBP1	2	two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sewalt RG (1999), Wang J (2011), Corominas R (2014), Rolland T (2014), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	8
APP	1	STUB1	4	affinity chromatography technology, affinity chromatography technology	Kumar P (2007), Kumar P (2007)	2
CTBP1	2	HELZ	6	affinity chromatography technology	Boldt K (2016)	1
SMAD6	9	CTBP2	7	affinity chromatography technology	Herhaus L (2014)	1
FOXE1	2	CTBP2	7	affinity chromatography technology	Li X (2015)	1
TRIM25	5	SOX13	4	affinity chromatography technology	Choudhury NR (2017)	1
RPL7A	1	RPS4X	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
SOX2	4	CTBP2	7	affinity chromatography technology	Engelen E (2011)	1
CTBP2	7	DVL2	5	two hybrid	Wang J (2011)	1
TRIM25	5	RAB11FIP1	2	affinity chromatography technology	Choudhury NR (2017)	1
STUB1	4	RUNX1	0	affinity chromatography technology, pull down, affinity chromatography technology	Shang Y (2009), Shang Y (2009), Shang Y (2009)	3
CTBP2	7	KLF8	0	two hybrid, pull down	van Vliet J (2000), van Vliet J (2000)	2
UBE2I	0	MDM2	2	pull down, affinity chromatography technology, enzymatic study, unspecified method	Buschmann T (2001), Buschmann T (2001), Buschmann T (2001), Buschmann T (2001)	4
UBC	7	FHL3	0	affinity chromatography technology	Matsumoto M (2005)	1
CTBP2	7	RAB11FIP1	2	affinity chromatography technology	Hein MY (2015)	1
CTBP2	7	PROX1	0	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
CTBP2	7	UBE2I	0	two hybrid	Wang J (2011)	1
HDAC2	1	WIZ	2	affinity chromatography technology	Bantscheff M (2011)	1
RPS4X	0	RPS29	0	biochemical	Kristensen AR (2012)	1
C15orf39	0	HELZ	6	affinity chromatography technology	Boldt K (2016)	1
UHRF2	1	CTBP2	7	affinity chromatography technology	Lai M (2016)	1
CTBP2	7	MVD	2	affinity chromatography technology	Hein MY (2015)	1
EHMT2	4	UHRF2	1	affinity chromatography technology, affinity chromatography technology	Zhang J (2011), Lai M (2016)	2
MED23	3	KAT2B	2	bioid	Lambert JP (2015)	1
SOX2	4	TSHZ3	6	affinity chromatography technology	Cox JL (2013)	1
CTBP2	7	NOL4	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
CTBP2	7	TSHZ3	6	two hybrid	Rolland T (2014)	1
CTBP1	2	NOL4	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Corominas R (2014), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	4
CTBP1	2	IKZF1	2	pull down, affinity chromatography technology, two hybrid, two hybrid, two hybrid	Koipally J (2000), Koipally J (2000), Vinayagam A (2011), Corominas R (2014), Rolland T (2014)	5
MDM2	2	RBBP8	1	affinity chromatography technology	Okoro DR (2013)	1
SMAD6	9	ZEB1	3	affinity chromatography technology, affinity chromatography technology	Nakahata S (2010), Nakahata S (2010)	2
CTBP1	2	KAT2B	2	enzymatic study, affinity chromatography technology, pull down	Fuks F (1998), Senyuk V (2005), Kim JH (2005)	3
TRIM25	5	MDM2	2	affinity chromatography technology	Choudhury NR (2017)	1
FOXI2	1	CTBP2	7	affinity chromatography technology	Li X (2015)	1
SOX2	4	SOX6	1	affinity chromatography technology	Cox JL (2013)	1
RPS29	0	RPS28	0	biochemical	Kristensen AR (2012)	1
NRIP1	4	APP	1	pull down	Olah J (2011)	1
HNRNPL	3	KCNIP3	1	affinity chromatography technology	Fei T (2017)	1
ZNF217	3	HIST3H3	0	enzymatic study	Shi Y (2003)	1
RPL7A	1	RPS28	0	biochemical	Havugimana PC (2012)	1
CBX4	1	HIST3H3	0	enzymatic study, unspecified method	Shi Y (2003), Vermeulen M (2010)	2
EGFR	5	RPL17	0	affinity chromatography technology	Li J (2013)	1
TRIM25	5	HNRNPL	3	affinity chromatography technology	Choudhury NR (2017)	1
KLF3	0	CTBP2	7	affinity chromatography technology, pull down, two hybrid	Turner J (2003), Turner J (1998), Turner J (1998)	3
KAT2B	2	CTBP2	7	affinity chromatography technology	Shimahara A (2010)	1
CDKN2A	1	ACTG1	5	pull down, biochemical	Souza-Rodrigues E (2007), Kristensen AR (2012)	2
CTBP2	7	RPL7A	1	two hybrid	Wang J (2011)	1
CTBP2	7	FOXP2	13	two hybrid	Rolland T (2014)	1
CTBP2	7	TEAD3	0	two hybrid	Rual JF (2005)	1
UBC	7	MRPS7	0	affinity chromatography technology	Matsumoto M (2005)	1
WIZ	2	EHMT1	18	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
CTBP2	7	ZC3H3	4	affinity chromatography technology	Hein MY (2015)	1
CBX4	1	WIZ	2	affinity chromatography technology	Hein MY (2015)	1
SOX2	4	ZEB1	3	affinity chromatography technology	Engelen E (2011)	1
FHL3	0	CTBP2	7	two hybrid, pull down	Turner J (2003), Turner J (2003)	2
EHMT1	18	CTBP1	2	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Ueda J (2006), Shi Y (2003), Huttlin EL (2015), Huttlin EL (2017)	4
HNRNPL	3	RBM4	1	affinity chromatography technology	Fei T (2017)	1
EHMT2	4	ZNF512B	2	two hybrid	Ravasi T (2010)	1
FLI1	2	UBE2I	0	two hybrid	van den Akker E (2005)	1
HDAC2	1	HIST3H3	0	enzymatic study	Shi Y (2003)	1
SOX2	4	CTBP1	2	affinity chromatography technology	Engelen E (2011)	1
MED23	3	RBBP8	1	genetic interference	Horlbeck MA (2018)	1
EGLN3	0	CTBP2	7	affinity chromatography technology	Rodriguez J (2016)	1
MTMR7	0	CTBP2	7	affinity chromatography technology	Li X (2016)	1
RCOR1	0	ZNF217	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	You A (2001), Banck MS (2009), Banck MS (2009), Cowger JJ (2007), Thillainadesan G (2008), Kuppuswamy M (2008)	6
MED23	3	EP300	36	bioid, affinity chromatography technology	Lambert JP (2015), Lambert JP (2015)	2
CTBP2	7	APP	1	pull down	Olah J (2011)	1
CDKN2A	1	RBM26	3	two hybrid	Daakour S (2016)	1
APP	1	ZC3H3	4	pull down, affinity chromatography technology	Virok DP (2011), Huttlin EL (2017)	2
ACTG1	5	CTBP2	7	two hybrid	Wang J (2011)	1
TGIF1	1	APP	1	pull down	Olah J (2011)	1
EGFR	5	CTBP1	2	affinity chromatography technology	Tong J (2014)	1
FOXS1	2	APP	1	pull down	Olah J (2011)	1
RCOR1	0	HIST3H3	0	enzymatic study	Shi Y (2003)	1
TRIM25	5	EGLN3	0	affinity chromatography technology	Choudhury NR (2017)	1
RPL17	0	RPS28	0	biochemical	Havugimana PC (2012)	1
MTMR7	0	CCNH	3	affinity chromatography technology	St-Denis N (2016)	1
CTBP2	7	BCAS3	4	two hybrid	Rolland T (2014)	1
KLF8	0	APP	1	pull down	Olah J (2011)	1
EGLN3	0	C15orf39	0	affinity chromatography technology	Rodriguez J (2016)	1
HELZ	6	MARF1	8	affinity chromatography technology	Boldt K (2016)	1
KCNIP3	1	CTBP2	7	affinity chromatography technology, two hybrid	Zaidi NF (2006), Zaidi NF (2006)	2
EGFR	5	APP	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
CTBP2	7	TGIF1	1	two hybrid, two hybrid, two hybrid	Rual JF (2005), Rolland T (2014), Yu H (2011)	3
CFTR	5	EGFR	5	affinity chromatography technology	Pankow S (2015)	1
EGLN3	0	CTBP1	2	affinity chromatography technology	Rodriguez J (2016)	1
CTBP1	2	DMRTB1	1	two hybrid	Rolland T (2014)	1
UBE2I	0	CASP8AP2	3	two hybrid, enzymatic study	Bandyopadhyay S (2010), Gocke CB (2005)	2
IKZF1	2	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Koipally J (2002), Kim J (1999), Kim J (1999)	3
EGLN3	0	CTPS1	2	affinity chromatography technology	Rodriguez J (2016)	1
FOXE1	2	WIZ	2	affinity chromatography technology	Li X (2015)	1
HNRNPL	3	CTBP1	2	affinity chromatography technology	Fei T (2017)	1
EP300	36	ZEB1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Mizuguchi Y (2012), Postigo AA (2003), Postigo AA (2003), Postigo AA (2003)	4
IKZF1	2	FOXP1	23	affinity chromatography technology, affinity chromatography technology, pull down	Bond J (2016), Bond J (2016), Bond J (2016)	3
HNRNPL	3	MARK3	2	affinity chromatography technology	Fei T (2017)	1
ECT2	2	CTBP1	2	affinity chromatography technology	Woods NT (2012)	1
HNRNPL	3	CTBP2	7	affinity chromatography technology	Fei T (2017)	1
TRIM25	5	XRCC6	3	affinity chromatography technology	Choudhury NR (2017)	1
CTBP2	7	NOL4L	4	two hybrid	Rolland T (2014)	1
SOX2	4	EHMT2	4	affinity chromatography technology	Cox JL (2013)	1
MTMR7	0	CTBP1	2	affinity chromatography technology	Li X (2016)	1
UBE2I	0	CFTR	5	enzymatic study, enzymatic study	Ahner A (2013), Gong X (2016)	2
EGLN3	0	STUB1	4	affinity chromatography technology	Rodriguez J (2016)	1
HNRNPL	3	LCOR	4	affinity chromatography technology	Fei T (2017)	1
HNRNPL	3	KLF8	0	affinity chromatography technology	Fei T (2017)	1
UHRF2	1	XRCC6	3	affinity chromatography technology	Liu Y (2016)	1
HNRNPL	3	BCAS3	4	affinity chromatography technology	Fei T (2017)	1
UBC	7	CDKN2A	1	pull down, imaging technique	Zhang X (2017), Zhang X (2017)	2
CTBP2	7	RBM4	1	affinity chromatography technology	Hein MY (2015)	1
CTBP2	7	AKTIP	3	two hybrid	Rual JF (2005)	1
FLI1	2	KAT2B	2	affinity chromatography technology, affinity chromatography technology	Asano Y (2007), Asano Y (2009)	2
HIC1	1	CTBP2	7	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Van Rechem C (2009), Van Rechem C (2009), Van Rechem C (2010), Stankovic-Valentin N (2006), Stankovic-Valentin N (2006)	5
RCOR1	0	CTBP1	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Banck MS (2009), Kuppuswamy M (2008), Kuppuswamy M (2008), Huttlin EL (2015), Huttlin EL (2017)	5
IKZF2	3	IKZF1	2	affinity chromatography technology, affinity chromatography technology	Kelley CM (1998), Huttlin EL (2017)	2
SOX6	1	CTBP2	7	two hybrid, affinity chromatography technology	Murakami A (2001), Murakami A (2001)	2
FOXE1	2	HNRNPL	3	affinity chromatography technology	Li X (2015)	1
CTBP2	7	ZNF217	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhao LJ (2009), Kuppuswamy M (2008), Hein MY (2015)	3
ZBTB42	0	CTBP2	7	affinity chromatography technology	Huttlin EL (2017)	1
CTBP2	7	HDAC2	1	affinity chromatography technology	Zhao LJ (2009)	1
AKTIP	3	EGFR	5	affinity chromatography technology, affinity chromatography technology	Muthusami S (2015), Subramanian PD (2016)	2
EP300	36	XRCC6	3	enzymatic study	Cohen HY (2004)	1
CTBP2	7	HIST3H3	0	enzymatic study	Shi Y (2003)	1
CTBP2	7	SOX13	4	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
TEAD3	0	STUB1	4	affinity chromatography technology	Hauri S (2013)	1
CTBP1	2	BCAS3	4	two hybrid	Rolland T (2014)	1
CTBP1	2	KLF3	0	two hybrid	Corominas R (2014)	1
TRIM25	5	CTPS1	2	affinity chromatography technology	Choudhury NR (2017)	1
ZBTB18	9	ZBTB42	0	affinity chromatography technology	Huttlin EL (2017)	1
FHL3	0	UBE2I	0	two hybrid	Rolland T (2014)	1
PROX1	0	EP300	36	two hybrid, affinity chromatography technology	Chen Q (2002), Chen Q (2002)	2
DDX19B	2	APP	1	pull down	Olah J (2011)	1
UBC	7	DDX19B	2	pull down	Zhang X (2017)	1
EGFR	5	CDC25C	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
CTBP1	2	HIST3H3	0	enzymatic study	Shi Y (2003)	1
CTBP1	2	HOXB5	0	two hybrid	Rolland T (2014)	1
STUB1	4	CFTR	5	enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Younger JM (2004), Summers DW (2009), Ren HY (2011), Meacham GC (2001), Schmidt BZ (2009), Alberti S (2004)	6
CTBP1	2	FOXP1	23	affinity chromatography technology	Li S (2004)	1
HNRNPL	3	PSMF1	0	affinity chromatography technology	Fei T (2017)	1
FOXS1	2	HDAC2	1	affinity chromatography technology	Li X (2015)	1
MED23	3	DYRK1B	1	affinity chromatography technology	Lambert JP (2015)	1
UBE2I	0	SOX6	1	enzymatic study	Fernandez-Lloris R (2006)	1
MDM2	2	HIST3H3	0	pull down, enzymatic study, affinity chromatography technology	Chen L (2010), Chen L (2010), Chen L (2010)	3
TRIM25	5	TEAD3	0	affinity chromatography technology	Choudhury NR (2017)	1
SPRTN	0	CTBP2	7	affinity chromatography technology	Kim MS (2013)	1
CTBP2	7	PLCB1	0	two hybrid	Rolland T (2014)	1
TGIF1	1	CTBP1	2	affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid	Melhuish TA (2000), Melhuish TA (2000), Merrill JC (2010), Rolland T (2014)	4
TRIM25	5	MARF1	8	affinity chromatography technology	Choudhury NR (2017)	1
CTBP1	2	RUNX1	0	affinity chromatography technology	Nitta E (2005)	1
CTBP2	7	FLI1	2	two hybrid	Rolland T (2014)	1
TRIM25	5	CTBP2	7	affinity chromatography technology	Choudhury NR (2017)	1
C15orf39	0	APP	1	pull down	Olah J (2011)	1
KCNIP3	1	UBE2I	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Palczewska M (2011), Palczewska M (2011), Palczewska M (2011)	3
HNRNPL	3	TRNT1	0	affinity chromatography technology	Fei T (2017)	1
ZNF512B	2	PPP1R15A	2	two hybrid	Colland F (2004)	1
RCOR1	0	HDAC2	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hakimi MA (2002), You A (2001), You A (2001), Battaglioli E (2002), Humphrey GW (2001), Humphrey GW (2001), Bantscheff M (2011), Joshi P (2013)	8
IKZF2	3	HDAC2	1	affinity chromatography technology	Koipally J (2002)	1
RBBP8	1	UBC	7	far western blotting, affinity chromatography technology	Murina O (2014), Unno J (2014)	2
CTPS1	2	CTBP2	7	biochemical	Wan C (2015)	1
MRPS7	0	CTBP2	7	affinity chromatography technology	Huttlin EL (2017)	1
MED23	3	CTBP2	7	affinity chromatography technology	Lambert JP (2015)	1
RPL17	0	MRPS7	0	biochemical	Wan C (2015)	1
EGFR	5	UBC	7	affinity chromatography technology, affinity chromatography technology	Tong J (2009), Bishop N (2002)	2
ZNF512B	2	XRCC6	3	two hybrid	Colland F (2004)	1
UBC	7	SGTA	1	affinity chromatography technology	Matsumoto M (2005)	1
EGLN3	0	DVL2	5	affinity chromatography technology	Rodriguez J (2016)	1
HIC1	1	CTBP1	2	two hybrid, affinity chromatography technology	Van Rechem C (2009), Stankovic-Valentin N (2006)	2
UBE2I	0	IKZF1	2	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
HIST3H3	0	HNRNPL	3	unspecified method	Vermeulen M (2010)	1
CTBP2	7	ZFPM2	4	pull down, two hybrid, pull down	Holmes M (1999), Holmes M (1999), Svensson EC (2000)	3
RUNX1	0	HDAC2	1	affinity chromatography technology, affinity chromatography technology	Kraemer OH (2008), Shia WJ (2012)	2
EGFR	5	STUB1	4	protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Deribe YL (2009), Wang T (2014), Wang T (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Chung C (2016), Chung C (2016)	8
KCNIP3	1	CTBP1	2	affinity chromatography technology	Zaidi NF (2006)	1
ZNF217	3	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Thillainadesan G (2008), Kuppuswamy M (2008), Joshi P (2013)	3
CBX4	1	CTBP2	7	two hybrid, affinity chromatography technology, affinity chromatography technology	Sewalt RG (1999), Sewalt RG (1999), Sewalt RG (1999)	3
CTBP2	7	TRNT1	0	biochemical	Kristensen AR (2012)	1
CTBP1	2	RAI2	0	two hybrid	Corominas R (2014)	1
VSX1	0	CTBP2	7	affinity chromatography technology	Huttlin EL (2015)	1
TRIM25	5	HIC1	1	affinity chromatography technology	Choudhury NR (2017)	1
ECT2	2	FHL3	0	affinity chromatography technology	Woods NT (2012)	1
CTBP1	2	EP300	36	affinity chromatography technology, pull down, affinity chromatography technology, pull down	Senyuk V (2005), Kim JH (2005), Kim JH (2005), Kim JH (2005)	4
WIZ	2	CTBP2	7	affinity chromatography technology	Ueda J (2006)	1
ZNF217	3	CTBP1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Banck MS (2009), Cowger JJ (2007), Thillainadesan G (2008), Kuppuswamy M (2008), Kuppuswamy M (2008), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	8
C15orf39	0	MARF1	8	affinity chromatography technology	Boldt K (2016)	1
MDM2	2	XRCC6	3	enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology	Gama V (2009), Gama V (2009), Gama V (2009), Okoro DR (2013)	4
MED23	3	RCOR1	0	affinity chromatography technology	Lambert JP (2015)	1
CTBP2	7	RIMBP3	0	two hybrid	Rolland T (2014)	1
EGFR	5	CTBP2	7	affinity chromatography technology	Tong J (2014)	1
CTBP2	7	GPALPP1	1	affinity chromatography technology	Hein MY (2015)	1
CTBP2	7	MARK3	2	affinity chromatography technology	Hein MY (2015)	1
CTBP1	2	LCOR	4	two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ravasi T (2010), Fernandes I (2003), Fernandes I (2003), Corominas R (2014), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	7
MDM2	2	CDKN2A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe	Zhang Y (2003), Zhang Y (2003), Zhang Y (2003), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Clark PA (2002), Clark PA (2002), Clark PA (2002), Pomerantz J (1998), Ivanchuk SM (2008), Wang C (2005), Wang X (2001), Midgley CA (2000), Shen J (2011), Li L (2010), Li L (2010), Li X (2011), Woods YL (2004), Bouska A (2008), Lindstroem MS (2007), Lohrum MA (2000), Wang J (2006), Wang J (2006), Wang J (2006), Drago-Ferrante R (2008), Schuster K (2007), Hogan C (2008), Rizos H (2000), Gargano B (2008), Kamijo T (1998), Wang S (2010), Jones R (2007), Stott FJ (1998), Lo D (2014), Pimkina J (2009), Blattner C (2002), Leslie PL (2015), Bothner B (2003), Ivanov AA (2017)	42
EGLN3	0	HELZ	6	affinity chromatography technology	Rodriguez J (2016)	1
ZNF512B	2	CTBP2	7	two hybrid	Colland F (2004)	1
SPRTN	0	UBC	7	pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down	Machida Y (2012), Machida Y (2012), Mosbech A (2012), Mosbech A (2012), Mosbech A (2012), Centore RC (2012), Davis EJ (2012)	7
CCNH	3	CTBP2	7	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
BCAS3	4	KAT2B	2	affinity chromatography technology	Gururaj AE (2007)	1
TRIM25	5	UBC	7	enzymatic study	Sanchez JG (2016)	1
MDM2	2	APP	1	pull down	Miyamoto-Sato E (2010)	1
ATXN1L	0	CTBP1	2	two hybrid	Lim J (2006)	1
RBBP8	1	IKZF1	2	affinity chromatography technology	Koipally J (2002)	1
EP300	36	HIST3H3	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Seo SB (2001), Ott M (1999), Thomas MC (2005), Sabari BR (2015), Sabari BR (2015), Yi P (2015)	6
UBE2I	0	HIC1	1	enzymatic study, affinity chromatography technology	Stankovic-Valentin N (2007), Dehennaut V (2013)	2
CTPS2	0	CTPS1	2	affinity chromatography technology	Huttlin EL (2017)	1
CTBP1	2	ZBTB18	9	two hybrid, affinity chromatography technology	Corominas R (2014), Huttlin EL (2017)	2
CTBP2	7	XRCC6	3	two hybrid	Wang J (2011)	1
CFTR	5	HDAC2	1	affinity chromatography technology	Pankow S (2015)	1
SOX2	4	RUNX1	0	affinity chromatography technology	Cox JL (2013)	1
CFTR	5	CTBP2	7	affinity chromatography technology	Pankow S (2015)	1
RUNX1	0	EP300	36	affinity chromatography technology, enzymatic study	Aikawa Y (2006), Yamaguchi Y (2004)	2
BCL3	2	EP300	36	two hybrid, pull down	Na SY (1999), Na SY (1999)	2
FOXP1	23	CTBP2	7	affinity chromatography technology	Li X (2015)	1
CTBP2	7	EP300	36	affinity chromatography technology	Zhao LJ (2009)	1
CTBP2	7	BAZ2B	15	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
EGLN3	0	ECT2	2	affinity chromatography technology	Rodriguez J (2016)	1
SOX2	4	CBX4	1	affinity chromatography technology	Cox JL (2013)	1
BCL3	2	CTBP2	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Keutgens A (2010), Keutgens A (2010), Wang J (2011), Wang J (2011)	4
CTBP2	7	HOXB5	0	two hybrid	Rolland T (2014)	1
EP300	36	MDM2	2	pull down, affinity chromatography technology, biochemical, pull down, pull down, enzymatic study, affinity chromatography technology, biochemical, enzymatic study	Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Matt T (2004), Wang X (2004), Gillotin S (2010), Kobet E (2000), Nihira NT (2017)	9
TRIM25	5	RPL7A	1	affinity chromatography technology	Choudhury NR (2017)	1
CTBP1	2	MARF1	8	affinity chromatography technology	Boldt K (2016)	1
KAT2B	2	XRCC6	3	enzymatic study	Cohen HY (2004)	1
CTBP2	7	RPL17	0	two hybrid	Wang J (2011)	1
CTBP1	2	TSHZ3	6	two hybrid	Rolland T (2014)	1
RUNX1	0	CTBP2	7	two hybrid	McGilvray R (2007)	1
CTBP2	7	RBBP8	1	two hybrid, affinity chromatography technology	Wang J (2011), Broderick R (2016)	2
TRIM25	5	RPS29	0	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
CTBP1	2	FUNDC1	0	two hybrid	Corominas R (2014)	1
CTBP1	2	C15orf39	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DYRK1B	1	CTBP2	7	affinity chromatography technology	Varjosalo M (2013)	1
TRIM25	5	NOL4L	4	affinity chromatography technology	Choudhury NR (2017)	1
EHMT1	18	CTBP2	7	affinity chromatography technology	Ueda J (2006)	1
CCR5	1	CTBP2	7	two hybrid	Wang J (2011)	1
CTBP2	7	RPS4X	0	two hybrid	Wang J (2011)	1