Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
CTH 1491 CYSTEINE CHEMBL54943 DrugBank 17634391, 16428267, 16108046
CTH 1491 AMINOETHOXYVINYLGLYCINE CHEMBL1972647 inhibitor GuideToPharmacologyInteractions
CTH 1491 CHEMBL50483 CHEMBL50483 DrugBank 10592235, 10954021
CTH 1491 PYRIDOXAL PHOSPHATE CHEMBL82202 cofactor DrugBank 16857832, 11578145, 15184188, 17377202, 15823094
CTH 1491 ALCOHOL CHEMBL545 DrugBank 10592235

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
CTH rs648743 TT busulfan metabolism/PK no Genotype TT is not associated with clearance of busulfan in children with hemopoietic stem cell transplant as compared to genotypes CC + CT. 27779248 1448525501
CTH rs1021737 TT busulfan metabolism/PK no Genotype TT is not associated with clearance of busulfan in children with hemopoietic stem cell transplant as compared to genotypes GG + GT. 27779248 1448525496