Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
CTNNB1 1499 TEMSIROLIMUS CHEMBL1201182 CKB 27016228
CTNNB1 1499 TRAMETINIB CHEMBL2103875 CKB 26343583
CTNNB1 1499 UREA CHEMBL985 DrugBank 17139284, 17016423, 10592235
CTNNB1 1499 VANTICTUMAB CHEMBL2364652 CKB 22753465
CTNNB1 1499 IMATINIB CHEMBL941 CKB 26861905
CTNNB1 1499 CELECOXIB CHEMBL118 PharmGKB
CTNNB1 1499 EVEROLIMUS CHEMBL1908360 CGI
CTNNB1 1499 LETROZOLE CHEMBL1444 CGI
CTNNB1 1499 TRICIRIBINE CHEMBL331237 CKB 26224873

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
CTNNB1 rs4135385 AA cyclophosphamide efficacy yes Genotype AA is associated with increased response to cyclophosphamide, dexamethasone and thalidomide in people with Multiple Myeloma as compared to genotypes AG + GG. 26521987 1447520580
CTNNB1 rs4533622 AA thalidomide efficacy yes Genotype AA is associated with increased response to thalidomide in people with Multiple Myeloma as compared to genotypes AC + CC. 26521987 1447520587