PPI network (data source: BioGrid)

Symbol A GeneA coding DNM count Symbol B GeneB coding DNM count Interaction detection method Publication Evidence
TP53 0 TP73 2 affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology Stindt MH (2015), Puca R (2011), De Laurenzi V (1998), Di Como CJ (1999) 4
CDH1 4 TRIM25 5 bioid Guo Z (2014) 1
RNASEH2B 0 DAB2IP 3 affinity chromatography technology Hein MY (2015) 1
XPO1 8 TP73 2 unspecified method Xu D (2012) 1
TP63 0 FBXW7 2 affinity chromatography technology Galli F (2010) 1
EXOSC9 2 DAB2IP 3 affinity chromatography technology Hein MY (2015) 1
PIK3R1 6 DAB2IP 3 pull down, affinity chromatography technology, affinity chromatography technology Xie D (2009), Xie D (2009), Xie D (2009) 3
CUL4A 2 TP53 0 affinity chromatography technology Banks D (2006) 1
SNX17 0 HRAS 2 pull down Ghai R (2013) 1
TP73 2 CUL1 7 affinity chromatography technology Peschiaroli A (2009) 1
FBXW7 2 RBX1 2 biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Busino L (2012), Matsumoto A (2011), Strohmaier H (2001), Ye M (2017) 4
AKT1 1 PIK3R1 6 affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe Xiong Y (2009), Xiong Y (2009), Ivanov AA (2017) 3
TRADD 0 TRAF2 1 affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Bouwmeester T (2004), Takeuchi M (1996), Park YC (2000), Tsao DH (2000), Tada K (2001), Hsu H (1996), Hsu H (1996), Malinin NL (1997), Vince JE (2009), Jang HD (2001), Park KJ (2003), Lin B (2016) 12
TP63 0 DAB2IP 3 affinity chromatography technology Lunardi A (2010) 1
TRIM25 5 DAB2IP 3 affinity chromatography technology Choudhury NR (2017) 1
TRIM25 5 CBY1 3 affinity chromatography technology Choudhury NR (2017) 1
XPO1 8 IWS1 3 affinity chromatography technology Kirli K (2015) 1
CBY1 3 DAB2IP 3 affinity chromatography technology Boldt K (2016) 1
TRIM25 5 CUL4A 2 affinity chromatography technology Choudhury NR (2017) 1
DAB2IP 3 SKP1 0 affinity chromatography technology Dai X (2014) 1
NTRK1 1 EXOSC9 2 affinity chromatography technology Emdal KB (2015) 1
SKP1 0 RBX1 2 affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Staropoli JF (2003), Kumar R (2005), Wang W (2004), Ohta T (2001), Oshikawa K (2003), Liu J (2002), Li X (2003), Zhou W (2014), Zhou W (2014), Hao J (2015), Hauri S (2016) 11
NTRK1 1 XPO1 8 affinity chromatography technology Emdal KB (2015) 1
TRAF2 1 DAB2IP 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Zhang H (2007), Zhang H (2004), Dai X (2014) 3
CD83 0 DAB2IP 3 affinity chromatography technology Huttlin EL (2017) 1
TNFRSF1A 3 TRAF2 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology Hsu H (1996), Hsu H (1996), Shu HB (1996), Vince JE (2009), Mahul-Mellier AL (2011), Won M (2010), Kolliputi N (2009), Park KJ (2002), Lee IT (2010), Kim WJ (2005), Zheng L (2006), Vince JE (2007), Jeon J (2014), Chen TC (2014), Lee CK (2015), Jeong M (2017) 16
XPO1 8 SNX17 0 affinity chromatography technology Kirli K (2015) 1
NTRK1 1 UGGT1 6 affinity chromatography technology Emdal KB (2015) 1
DAB2 1 DAB2IP 3 affinity chromatography technology, pull down Wang Z (2002), Wang Z (2002) 2
PIK3R1 6 MAP3K5 1 affinity chromatography technology, affinity chromatography technology Xie D (2009), Xie D (2009) 2
TRADD 0 DAB2IP 3 affinity chromatography technology Zhang H (2004) 1
CBY1 3 CGN 4 affinity chromatography technology Boldt K (2016) 1
XPO1 8 TRADD 0 affinity chromatography technology Kirli K (2015) 1
CUL1 7 UGGT1 6 affinity chromatography technology Bennett EJ (2010) 1
TRIM25 5 ANKS1A 3 affinity chromatography technology Choudhury NR (2017) 1
PIK3R1 6 HRAS 2 affinity chromatography technology, pull down, imaging technique Hanna AN (1999), Rodriguez-Viciana P (1997), Chen TC (2014) 3
FBXW7 2 TRIM25 5 two hybrid Arroyo R (2015) 1
TNFRSF1A 3 TRADD 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Jiang Y (1999), Schuetze S (1999), Pan G (1997), Hsu H (1996), Hsu H (1996), Hsu H (1996), Shu HB (1996), Blankenship JW (2009), Kolliputi N (2009), Fujikura D (2012), Park KJ (2002), Guan YJ (2011), Hsu H (1995), Kumar A (2001), Zheng L (2006), Kim TW (2013), Zhang H (2004), Chang YL (2014), Nakazawa S (2016), Huttlin EL (2017) 20
SKP1 0 CUL1 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Staropoli JF (2003), Min KW (2003), Lisztwan J (1998), Zheng N (2002), Ohta T (1999), Bloom J (2006), Kumar R (2005), Megumi Y (2005), Wang W (2004), Read MA (2000), Wu K (2000), Tan P (1999), Mao X (2011), Lin HK (2009), Yano H (2008), Banerjee S (2010), Gao D (2010), Chua YS (2011), Zhang M (2008), Winston JT (1999), Latres E (1999), Latres E (1999), Arai T (2003), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), Emberley ED (2012), Bennett EJ (2010), Gastaldello S (2012), Michel JJ (1998), Michel JJ (1998), Michel JJ (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Furukawa M (2000), Furukawa M (2000), Liu J (2002), Liu J (2002), Liu J (2002), Yu ZK (1998), Yu ZK (1998), Postow L (2013), Cordero-Espinoza L (2013), Zhou W (2014), Zhou W (2014), Hao J (2015), Hao J (2015), Han XR (2016), Liu YQ (2015), Gorelik M (2016), Al-Yacoub N (2016), Reiterer V (2017), Hu Y (2017), Hauri S (2016), Reitsma JM (2017), Reitsma JM (2017), Chen F (2017) 59
HRAS 2 DAB2IP 3 affinity chromatography technology Dai X (2014) 1
RBX1 2 DAB2IP 3 affinity chromatography technology, affinity chromatography technology Dai X (2014), Dai X (2014) 2
HRAS 2 TP53 0 affinity chromatography technology Aylon Y (2010) 1
TRIM25 5 TNFRSF1A 3 affinity chromatography technology Choudhury NR (2017) 1
RFPL3 0 DAB2IP 3 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
CUL1 7 RBX1 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, enzymatic study, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, pull down, x-ray crystallography, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Min KW (2003), Dias DC (2002), Kim J (2002), Zheng N (2002), Kim AY (2008), Ohta T (1999), Ohta T (1999), Ohta T (1999), Bloom J (2006), Block K (2005), Hu J (2004), Hwang JW (2003), Furukawa M (2002), Kawakami T (2001), Ohta T (2001), Chen A (2000), Read MA (2000), Wu K (2000), Tan P (1999), Banerjee S (2010), Gao D (2010), Tron AE (2012), Tron AE (2012), Shteingart S (2012), Tan M (2010), Arai T (2003), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), Huang DT (2004), Emberley ED (2012), Gastaldello S (2012), Furukawa M (2000), Furukawa M (2000), Liu J (2002), Liu J (2002), Liu J (2002), Li X (2003), Calabrese MF (2011), Scott DC (2014), Scott DC (2014), Siergiejuk E (2009), Zhou W (2014), Zhou W (2014), Huang DT (2009), Pick E (2007), Morimoto M (2003), Morimoto M (2003), Ohki Y (2009), Duda DM (2008), Duda DM (2008), Wan C (2015), Hao J (2015), Hao J (2015), Han XR (2016), Kuang P (2016), Zhou W (2017), Hu Y (2017), Reitsma JM (2017) 59
TP53 0 RBX1 2 affinity chromatography technology Fogeron ML (2013) 1
XPO1 8 RIPK1 2 affinity chromatography technology Kirli K (2015) 1
DAB2IP 3 FBXW7 2 affinity chromatography technology Dai X (2014) 1
TP53 0 SKP1 0 affinity chromatography technology Fogeron ML (2013) 1
NTRK1 1 CUL1 7 affinity chromatography technology Emdal KB (2015) 1
TRIM25 5 YWHAQ 0 affinity chromatography technology Choudhury NR (2017) 1
RIPK1 2 DAB2IP 3 affinity chromatography technology, affinity chromatography technology Zhang H (2007), Zhang H (2004) 2
DAB2IP 3 CUL1 7 affinity chromatography technology Dai X (2014) 1
IWS1 3 DAB2IP 3 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 PIK3R1 6 affinity chromatography technology Emdal KB (2015) 1
CDH1 4 DAB2IP 3 bioid Guo Z (2014) 1
TP53 0 DAB2IP 3 affinity chromatography technology Lunardi A (2010) 1
MAP3K5 1 DAB2IP 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Zhang H (2007), Xie D (2009), Xie D (2009), Zhang H (2004), Zhang H (2004), Wang H (2015) 6
TRIM25 5 XPO1 8 affinity chromatography technology Choudhury NR (2017) 1
TRIM25 5 CGN 4 affinity chromatography technology Choudhury NR (2017) 1
TP73 2 DAB2IP 3 affinity chromatography technology Lunardi A (2010) 1
SNX17 0 NTRK1 1 affinity chromatography technology Ghai R (2013) 1
TMEM206 5 DAB2IP 3 affinity chromatography technology Huttlin EL (2017) 1
CGN 4 YWHAQ 0 affinity chromatography technology Huttlin EL (2017) 1
XPO1 8 DAB2IP 3 affinity chromatography technology Kirli K (2015) 1
CTDSPL 1 DAB2IP 3 bioid St-Denis N (2016) 1
TNFRSF1A 3 AKT1 1 fluorescent resonance energy transfe Ivanov AA (2017) 1
YWHAQ 0 MAP3K5 1 pull down Zhang H (2007) 1
XPO1 8 DAB2 1 affinity chromatography technology Kirli K (2015) 1
YWHAQ 0 DAB2IP 3 pull down, affinity chromatography technology Zhang H (2007), Zhang H (2007) 2
DAB2IP 3 AKT1 1 affinity chromatography technology, affinity chromatography technology, enzymatic study Xie D (2009), Xie D (2009), Dai X (2014) 3
DAB2IP 3 ANKS1A 3 affinity chromatography technology Huttlin EL (2017) 1
TNFRSF1A 3 DAB2IP 3 affinity chromatography technology Zhang H (2004) 1
FBXW7 2 RAB4B 1 genetic interference Bailey ML (2015) 1
FBXW7 2 CUL1 7 pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Wu G (2001), Tron AE (2012), Busino L (2012), Busino L (2012), Busino L (2012), Matsumoto A (2011), Bennett EJ (2010), Strohmaier H (2001), Davis MA (2013), JunGang Z (2012), Busino L (2003), Pierce NW (2013), Chung FZ (2014), Yumimoto K (2012), Low TY (2014), Kourtis N (2015), Gorelik M (2016), Gorelik M (2016), Huttlin EL (2017), Reiterer V (2017), Reiterer V (2017), Ye M (2017), Reitsma JM (2017) 23
TNFRSF1A 3 PIK3R1 6 affinity chromatography technology Pincheira R (2008) 1
DAB2IP 3 MCC 3 affinity chromatography technology Huttlin EL (2017) 1
DAB2IP 3 CUL4A 2 affinity chromatography technology Dai X (2014) 1
CDH1 4 CGN 4 bioid Guo Z (2014) 1
TRIM25 5 IWS1 3 affinity chromatography technology Choudhury NR (2017) 1
CUL1 7 AKT1 1 affinity chromatography technology Reitsma JM (2017) 1
DAB2IP 3 SNX17 0 affinity chromatography technology Huttlin EL (2017) 1
CUL4A 2 CUL1 7 biochemical He YJ (2006) 1
RAB4B 1 DAB2IP 3 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 YWHAQ 0 affinity chromatography technology Emdal KB (2015) 1
TRAF2 1 FBXW7 2 affinity chromatography technology Huttlin EL (2017) 1
RIPK1 2 TNFRSF1A 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Kim JW (2000), Duan H (1997), Hsu H (1996), Blankenship JW (2009), Newton K (2008), Varfolomeev E (2008), Fearns C (2006), Vince JE (2009), Dynek JN (2010), Kim S (2010), Cheung HH (2009), Tenev T (2011), Mahul-Mellier AL (2011), Won M (2010), Glowacka WK (2012), Fan YH (2011), Cusson-Hermance N (2005), ODonnell MA (2012), Zheng L (2006), Vince JE (2007), Mitsuhashi S (2008), Kim TW (2013), Wertz IE (2004), Liao W (2008), Wang YB (2015), Chang YL (2014), Zilberman-Rudenko J (2016), Zemirli N (2014), Moquin DM (2013), Nakazawa S (2016), Jeong M (2017), Huttlin EL (2017), Elliott PR (2016) 33
RNASEH2B 0 YWHAQ 0 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 DAB2IP 3 affinity chromatography technology Emdal KB (2015) 1
TP53 0 TP63 0 genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology McDade SS (2011), Lu D (2013), Chae YS (2012), Chae YS (2012), Stindt MH (2015), Wei S (2014) 6
UGGT1 6 DAB2IP 3 affinity chromatography technology Hein MY (2015) 1
TRAF2 1 RIPK1 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Takeuchi M (1996), Tada K (2001), Hsu H (1996), Hsu H (1996), Malinin NL (1997), Knox PG (2011), Ea CK (2006), Chang EJ (2011), Vince JE (2009), Alvarez SE (2010), Jang HD (2001), Shen RR (2012), Shen RR (2012), Puliyappadamba VT (2013), Hu MM (2014), Jeon J (2014), Rolland T (2014), Park ES (2015), Petersen SL (2015), Lin B (2016), Lin B (2016) 21
TP53 0 AKT1 1 fluorescent resonance energy transfe Ivanov AA (2017) 1
SKP1 0 FBXW7 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology Staropoli JF (2003), Wu G (2001), Wu G (2001), Wu G (2001), Hao B (2007), Schuelein C (2011), Busino L (2012), Busino L (2012), Busino L (2012), Matsumoto A (2011), Watanabe N (2004), Strohmaier H (2001), Choi BH (2014), Yumimoto K (2012), Kourtis N (2015), Kourtis N (2015), Hao J (2015), Tian X (2015), Liu YQ (2015), Gorelik M (2016), Gorelik M (2016), Gorelik M (2016), Yeh CH (2016), Reiterer V (2017), Reiterer V (2017), Reiterer V (2017), Kuchay S (2017), Ye M (2017) 28
DAB2IP 3 CGN 4 affinity chromatography technology Huttlin EL (2017) 1
RBX1 2 CUL4A 2 affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, biochemical, enzymatic study, pull down, biochemical Dias DC (2002), Ohta T (1999), Guerrero-Santoro J (2008), Hu J (2004), Furukawa M (2002), Maddika S (2009), Tron AE (2012), Tron AE (2012), He YJ (2006), Gastaldello S (2012), Olma MH (2009), Kristensen AR (2012), Huang DT (2009), Pick E (2007), Yang Y (2016), Scherer PC (2016), Nguyen TV (2016) 17
FBXW7 2 TP53 0 affinity chromatography technology Huttlin EL (2017) 1
TRADD 0 RIPK1 2 two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Hsu H (1996), Hsu H (1996), Hsu H (1996), Ea CK (2006), Guan YJ (2011), Jeon J (2014), Lin B (2016) 7
AKT1 1 MAP3K5 1 affinity chromatography technology, enzymatic study Kim AH (2001), Kim AH (2001) 2
CUL4A 2 SKP1 0 affinity chromatography technology, affinity chromatography technology Bennett EJ (2010), Gastaldello S (2012) 2
TRAF2 1 MAP3K5 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down Nishitoh H (1998), Hoeflich KP (1999), Gan B (2006), Kolliputi N (2009), Fujino G (2007), Fujino G (2007), Wu Y (2006), Zhang H (2004), Hwang SG (2014), Yoon KW (2009), Yoon KW (2009) 11
TP63 0 TP73 2 affinity chromatography technology Huttlin EL (2017) 1
DAB2IP 3 CLIP1 2 affinity chromatography technology Huttlin EL (2017) 1