Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
CYP2E1 1571 PERFLUBRON CHEMBL1200866 NCI 8399771
CYP2E1 1571 ISOFLAVONE CHEMBL366460 NCI 15056880
CYP2E1 1571 RITONAVIR CHEMBL163 NCI 9278209
CYP2E1 1571 CHLORPROMAZINE CHEMBL71 NCI 15135088
CYP2E1 1571 CYTARABINE CHEMBL803 PharmGKB
CYP2E1 1571 FLUOROURACIL CHEMBL185 NCI 12904931
CYP2E1 1571 POLYETHYLENE GLYCOL CHEMBL1201478 NCI 10634315
CYP2E1 1571 VALERIAN CHEMBL2108165 NCI 15900287
CYP2E1 1571 GEMTUZUMAB OZOGAMICIN CHEMBL1201506 PharmGKB
CYP2E1 1571 SODIUM beta-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE CHEMBL295069 NCI 14744944
CYP2E1 1571 CIPROFLOXACIN CHEMBL8 NCI 15194011

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
CYP2E1 rs2515641 T risperidone efficacy no The T allele was initially significantly more frequent in patients designated as responders to risperidone (i.e. >50% reduction in PANSS score compared to the cohort average). However, significance was lost following correction for multiple testing. Allele T is associated with increased response to risperidone in people with Schizophrenia as compared to allele C. 28696411 1450928135