PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
YWHAQ	0	TSC2	17	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical	Ewing RM (2007), Pozuelo-Rubio M (2010), Meek SE (2004), Pozuelo-Rubio M (2010), Pozuelo-Rubio M (2010)	5
TP53	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Wang C (2003), Akakura S (2001), Peng Y (2001), Nagata Y (1999), Wang J (2011), Burch L (2004), Taipale M (2012), Fogeron ML (2013), Walerych D (2004)	9
SVIL	9	CALM1	0	affinity chromatography technology	Nebl T (2002)	1
HSP90AA1	7	IKBKG	0	affinity chromatography technology, affinity chromatography technology	Gano JJ (2010), Hein MY (2015)	2
LRRK2	5	CAPZB	2	affinity chromatography technology	Meixner A (2011)	1
LRRK2	5	CALM1	0	affinity chromatography technology	Meixner A (2011)	1
DAPK1	6	ST13	2	affinity chromatography technology, affinity chromatography technology	Zhang L (2007), Zhang L (2007)	2
TP53	0	DDX5	2	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
CUL3	17	EEF2	11	affinity chromatography technology	Bennett EJ (2010)	1
IKBKG	0	PPP2CA	7	affinity chromatography technology	Kray AE (2005)	1
PPP2R1B	4	EEF2	11	affinity chromatography technology	Sablina AA (2007)	1
TP53	0	PDCD6	2	affinity chromatography technology	Fogeron ML (2013)	1
PPP2CA	7	DAPK1	6	enzymatic study, affinity chromatography technology	Widau RC (2010), Guenebeaud C (2010)	2
DAPK1	6	MYO1D	3	affinity chromatography technology	So J (2015)	1
TP53	0	CAPZB	2	affinity chromatography technology	Horikawa I (2014)	1
DAPK1	6	BAG2	0	affinity chromatography technology	So J (2015)	1
CUL3	17	DDX5	2	affinity chromatography technology	Bennett EJ (2010)	1
LRRK2	5	TMOD3	0	affinity chromatography technology	Meixner A (2011)	1
YWHAQ	0	PDCD6	2	pull down	Meek SE (2004)	1
DAPK1	6	UNC5A	3	affinity chromatography technology	Llambi F (2005)	1
IVNS1ABP	0	KLHL20	2	affinity chromatography technology, affinity chromatography technology, pull down	Chen HY (2015), Chen HY (2015), Chen HY (2015)	3
PPP2CA	7	UNC5B	8	affinity chromatography technology	Guenebeaud C (2010)	1
DAPK1	6	ACTC1	5	affinity chromatography technology	So J (2015)	1
CUL3	17	BAG2	0	affinity chromatography technology	Bennett EJ (2010)	1
HSP90AA1	7	EEF2	11	affinity chromatography technology	Falsone SF (2005)	1
PPP2R1B	4	DAPK1	6	affinity chromatography technology	Guenebeaud C (2010)	1
CALM1	0	HSP90AA1	7	pull down	Ning YM (1995)	1
DAPK1	6	TTLL3	0	affinity chromatography technology	So J (2015)	1
CAPZA2	1	MYO1B	5	affinity chromatography technology	Hein MY (2015)	1
CALM1	0	DDX5	2	pull down, affinity chromatography technology	Shen X (2005), Jang DJ (2007)	2
LRRK2	5	DAPK1	6	affinity chromatography technology, affinity chromatography technology	Klein CL (2009), Klein CL (2009)	2
HSP90AA1	7	TPM3	0	affinity chromatography technology, biochemical	Falsone SF (2005), Kristensen AR (2012)	2
DAPK1	6	TP53	0	affinity chromatography technology, affinity chromatography technology	Craig AL (2007), Craig AL (2007)	2
MAPK1	1	TSC2	17	pull down, affinity chromatography technology	Ma L (2005), Ma L (2005)	2
TP53	0	BAG2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014), Horikawa I (2014), Yue X (2016)	4
DAPK1	6	TPM3	0	affinity chromatography technology	So J (2015)	1
PPP2R5A	2	PPP2R1B	4	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical	Goudreault M (2009), Zhou J (2003), Zhou J (2003), McCright B (1996), McCright B (1996)	5
PPP2R1A	8	EEF2	11	affinity chromatography technology	Sablina AA (2007)	1
55844	0	PPP2R1B	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Glatter T (2009), Huttlin EL (2017), Yadav L (2017), Yadav L (2017)	4
LRRK1	12	DAPK1	6	affinity chromatography technology, affinity chromatography technology	Klein CL (2009), Klein CL (2009)	2
MDM2	2	DAPK1	6	unspecified method	Burch LR (2004)	1
55844	0	DAPK1	6	affinity chromatography technology, affinity chromatography technology, enzymatic study	Widau RC (2010), Widau RC (2010), Widau RC (2010)	3
PPP2R1A	8	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Aranda-Orgilles B (2008), Gano JJ (2010)	2
DAPK1	6	CAPZB	2	affinity chromatography technology	So J (2015)	1
BECN1	2	TP53	0	affinity chromatography technology	Verma N (2017)	1
CAPZA2	1	CORO1C	2	affinity chromatography technology	Hein MY (2015)	1
CUL3	17	FADD	1	affinity chromatography technology	Gonzalvez F (2012)	1
MDM2	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, protein complementation assay, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, unspecified method, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, biochemical, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, protein complementation assay, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, imaging technique, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, pull down, unspecified method, fluorescent resonance energy transfe, two hybrid, pull down	Li M (2003), Latonen L (2001), Zhang Y (2003), Zhang Y (2003), Kurki S (2003), Kurki S (2003), Freeman DJ (2003), Ito A (2002), Ito A (2002), Grossman SR (1998), Fang S (2000), Liu G (2000), Zhang Y (1998), Zhang Y (1998), Chen J (1993), Thut CJ (1997), Leung KM (2002), Wawrzynow B (2009), Ochocka AM (2009), Chen D (2009), Hedstroem E (2009), Brenkman AB (2008), Qiu W (2008), Qiu W (2008), Zhang Z (2008), Muller P (2008), Colaluca IN (2008), Colaluca IN (2008), Colaluca IN (2008), Tang Y (2008), Tang Y (2008), Lu X (2007), Lukashchuk N (2007), Lukashchuk N (2007), Lee JH (2007), Carter S (2007), Sasaki M (2007), Brooks CL (2007), Li L (2007), Becker K (2007), Zhao BX (2006), Zhao BX (2006), Abida WM (2007), Yang WH (2006), Ma J (2006), Wallace M (2006), Shimizu H (2006), Andrews P (2006), Yang J (2009), Zhu Z (2009), Wang C (2005), Higashitsuji H (2005), Higashitsuji H (2005), Yan C (2005), Vega FM (2004), Dai MS (2004), Dai MS (2004), Groenroos E (2004), Ohkubo S (2006), Sui G (2004), Di Stefano V (2004), Brignone C (2004), Katayama H (2004), Linares LK (2003), OKeefe K (2003), Wang W (2003), Blattner C (2002), Matt T (2004), Matt T (2004), Eyckerman S (2005), Shimizu H (2002), Shimizu H (2002), Migliorini D (2002), Gu J (2001), Sengupta S (2001), Chernov MV (2001), Cross B (2011), Cross B (2011), Cross B (2011), Buschmann T (2001), Nakamura S (2000), Rodriguez MS (2000), Rodriguez MS (2000), Geyer RK (2000), Zaika A (1999), Maki CG (1999), Chen L (2010), Chen L (2010), Lin RK (2010), Fuchs SY (1998), Xirodimas DP (2001), Fuchs SY (1998), Inoue T (2001), Wu L (2011), Du W (2009), Li DQ (2009), Illuzzi JL (2011), Oliver TG (2011), Kim MM (2007), Marchenko ND (2007), Vaseva AV (2009), Vaseva AV (2009), Lai KP (2010), Naderi EH (2011), Zdzalik M (2010), Singh RK (2007), Meng L (2011), Moore L (2007), Kim S (2010), Inoue Y (2011), Fraser JA (2010), Worrall EG (2009), Wu H (2011), Wang KS (2011), Wang KS (2011), Wang KS (2011), Izumi T (2010), Huang YF (2009), Tang J (2006), Tang J (2006), Fu X (2010), Fu X (2010), Shloush J (2011), Yadavilli S (2009), Stevenson LF (2007), Suzuki T (2010), Cheng Q (2009), Kulikov R (2010), Kulikov R (2010), Li L (2010), Li L (2010), Cheng Q (2011), Li D (2011), Nie J (2010), Demma M (2010), Sun XX (2011), Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010), Nishida T (2011), Li M (2011), Li M (2011), Amson R (2011), Amson R (2011), Bhatt P (2011), David Y (2011), Zhang Y (2010), Liu J (2010), Liu J (2010), Song MS (2008), Cummins JM (2004), Kim CK (2010), Kim CK (2010), Yan C (2010), Wang X (2011), Phillips A (2010), Phillips A (2010), Kang HN (2011), Kang HN (2011), Wang X (2004), Sionov RV (2001), Wei S (2012), Camus S (2012), Ding B (2012), Yang Z (2012), Yang Z (2012), Tripathi V (2007), Tripathi V (2007), Dai C (2011), Chen S (2012), Honda R (1997), Kinyamu HK (2003), Zhan C (2012), Zhan C (2012), Lee CW (2010), Zhou X (2012), Bouska A (2008), Wade M (2012), Ferreon JC (2009), Domenici F (2011), Uldrijan S (2007), Uldrijan S (2007), Stad R (2000), Stad R (2000), Banks D (2006), Banks D (2006), Bernal F (2010), Bernal F (2010), Jain AK (2012), Kane SA (2000), Tan Z (2000), Yang Z (2012), Wawrzynow B (2007), Wawrzynow B (2007), Wawrzynow B (2007), Hiramatsu K (2006), Bao-Lei T (2006), Kulikov R (2005), Yang Y (2005), Lindstroem MS (2007), Bech-Otschir D (2001), Li Y (2012), Gillotin S (2010), Burch L (2004), Liu WL (2001), OHagan HM (2004), OHagan HM (2004), Funari G (2009), Candeias MM (2008), Brew CT (2006), Wang J (2011), Calabro V (2002), Burch L (2004), Iyappan S (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Kurki S (2004), Tian LF (2006), Wang J (2006), Bae S (2012), Bae S (2012), Frazier DP (2012), Frazier DP (2012), Lew QJ (2012), Lew QJ (2012), Huart AS (2012), Li Z (2004), Balint E (1999), Balint E (1999), Funston G (2012), Dou X (2012), Sadagopan S (2012), Sadagopan S (2012), Dixit D (2012), Roxburgh P (2012), Xu L (2012), Drago-Ferrante R (2008), Li H (2009), Negorev D (2001), Wang X (2012), Wang X (2012), Wang X (2012), Boettger A (1997), Jung H (2008), Oliner JD (1992), Seemann S (2005), Kawai H (2007), Schuster K (2007), Dawson R (2003), DArcy P (2009), Schon O (2004), Schon O (2004), Hogan C (2008), Lottin-Divoux S (2005), Latini P (2011), Latini P (2011), Latini P (2011), McCoy MA (2003), Kussie PH (1996), Shieh SY (1997), Shieh SY (1997), Naski N (2009), Naski N (2009), Schon O (2002), Tamborini E (2001), Wade M (2006), Wade M (2006), Lohrum MA (2003), Garcia JF (2002), Garcia JF (2002), Kallen J (2009), Kulikov R (2006), Kulikov R (2006), Czarna A (2009), Czarna A (2009), Hu B (2007), Chi SW (2005), Yu GW (2006), Yu GW (2006), Saji S (2001), Chen L (1997), Zhang H (1998), Issaeva N (2004), Wade M (2008), Wade M (2008), Chen HF (2007), Chen HF (2007), Li HH (2004), Wang J (2011), Gu L (2009), Gu L (2009), Meng L (2008), Meng L (2008), Okamoto K (2006), Malaguarnera R (2008), Zhou M (2003), Zhou M (2003), Di Conza G (2012), Xirodimas DP (2004), Auger KR (2005), Li J (2011), Li J (2011), Li J (2011), Lee SJ (2007), Chau JF (2012), Lu X (2005), Mazars A (2010), Mazars A (2010), Mazars A (2010), Olson DC (1993), Picksley SM (1994), Issaeva N (2004), Issaeva N (2004), Zhang J (2012), Wen W (2013), Wen W (2013), Bursac S (2012), Yang Y (2013), Yang Y (2013), Landre V (2013), Pettersson S (2012), Thin TH (2007), Thin TH (2007), Piccinin S (2012), Shan B (2012), Caratozzolo MF (2012), Lui K (2013), Kobet E (2000), Lim KH (2010), Ranaweera RS (2013), Cui D (2013), Ebina M (2013), He Y (2013), He Y (2013), Siepe D (2009), Suh HW (2013), Zhan YA (2013), Wang J (2011), Hjerpe R (2010), Murray MF (2007), Jin L (2013), Jin L (2013), Zhang R (2013), Yan S (2013), Sun XX (2011), Heyne K (2014), Heyne K (2014), Bista M (2013), Jin J (2014), Mikawa T (2014), Qi M (2014), Cheng Q (2014), Zhang HH (2014), Perry ME (2000), Nishizaki M (2004), Sanchez-Aguilera A (2006), Chen YC (2013), Bertamino A (2013), Ding G (2013), Kubo N (2013), Kubo N (2013), Hsueh KW (2013), Kofod-Olsen E (2014), Fogeron ML (2013), Chang YS (2013), Gotoh T (2014), Gotoh T (2014), Oi N (2014), Corcoran CA (2009), Corcoran CA (2009), Ayroldi E (2014), Wu G (2014), Rajendra R (2004), Zhang J (2014), Lee MG (2014), Lee MG (2014), Freedman DA (1997), Freedman DA (1997), Saxena A (2006), Shi D (2009), Lohrum MA (2001), Lohrum MA (2001), Grossman SR (2003), Yan S (2013), Xirodimas DP (2004), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Saville MK (2004), Rodriguez MS (1999), Lui K (2013), Wu PY (2003), Pavithra L (2009), He Y (2013), Tan BX (2014), Huttlin EL (2015), Marcar L (2015), Borcherds W (2014), Borcherds W (2014), Li YC (2014), Ayroldi E (2014), Ling X (2014), Batuello CN (2015), Zhu N (2006), Mo XL (2015), Chen TC (2014), Stindt MH (2015), Caratozzolo MF (2014), Li X (2015), Saxena R (2016), Reed SM (2014), Du C (2016), Du C (2016), Du C (2016), Fraser JA (2015), Fraser JA (2015), Wu B (2015), Qin JJ (2015), Raza S (2015), Raza S (2015), Yamauchi T (2014), Yamauchi T (2014), Yamauchi T (2014), Shi Y (2010), Ahn HJ (2015), Lim KH (2015), Kang JH (2016), Chen J (2015), Liu X (2016), Yang P (2016), Yang P (2016), Liu D (2016), Liu D (2016), Liu D (2016), Datta D (2015), Reddy BA (2014), He X (2016), Shostak K (2014), Liu LJ (2016), Liu LJ (2016), Stegh AH (2010), Liu XH (2005), Medina-Medina I (2016), Medina-Medina I (2016), Kayama K (2017), Singh AK (2016), Liu WT (2016), Yue X (2016), Soares J (2015), Mukhopadhyay R (2016), Mukhopadhyay R (2016), Zhou X (2016), Zhou X (2016), Xie X (2016), Leao M (2015), Luo H (2016), Luo H (2016), Xie N (2016), Maeda R (2017), Maeda R (2017), Maeda R (2017), Sheng W (2017), Sheng W (2017), Liu M (2010), Huttlin EL (2017), Chauhan KM (2016), Goetz C (1999), Zhang J (2017), Unger T (1999), Liu Z (2004), Wu W (2015), Tan G (2017), Nomura K (2017), Lu W (2017), Lu W (2017), Hjerrild M (2001), Landre V (2017), Landre V (2017), Landre V (2017), Landre V (2017), Shangary S (2008), Shangary S (2008), Du WW (2017), Du WW (2017), Bista M (2013), Bista M (2013), Jin M (2017), LaRusch GA (2007), LaRusch GA (2007), Kurokawa M (2013), Ivanov AA (2017), Wong JH (2017), Wong JH (2017)	496
DAPK1	6	CUL3	17	affinity chromatography technology	Lee YR (2010)	1
LRRK2	5	LRRK1	12	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Klein CL (2009), Dachsel JC (2010), Dachsel JC (2010)	3
CUL3	17	PPP2R1A	8	affinity chromatography technology	Bennett EJ (2010)	1
TSC2	17	CALM1	0	far western blotting, pull down, unspecified method, pull down	Noonan DJ (2002), Noonan DJ (2002), Noonan DJ (2002), York B (2005)	4
TP53	0	TPM3	0	affinity chromatography technology	Horikawa I (2014)	1
LRRK2	5	MYO1B	5	affinity chromatography technology	Meixner A (2011)	1
HSP90AA1	7	ST13	2	affinity chromatography technology, pull down, pull down	Gano JJ (2010), Graumann K (2000), Sun L (2012)	3
TP53	0	CORO1C	2	affinity chromatography technology	Horikawa I (2014)	1
TMOD3	0	ACTC1	5	affinity chromatography technology	Huttlin EL (2017)	1
DAPK1	6	MYO1B	5	affinity chromatography technology	So J (2015)	1
DDX5	2	EEF2	11	biochemical	Havugimana PC (2012)	1
CUL3	17	TPM3	0	affinity chromatography technology	Bennett EJ (2010)	1
PPP2CA	7	PPP2R1B	4	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Goudreault M (2009), Zhou J (2003), Zhou J (2003), Glatter T (2009), Sablina AA (2007), Sablina AA (2007), Havugimana PC (2012), Wan C (2015), Hein MY (2015), Yadav L (2017)	10
CAPZA2	1	TMOD3	0	affinity chromatography technology	Hein MY (2015)	1
PPP2R5A	2	DAPK1	6	affinity chromatography technology, affinity chromatography technology, enzymatic study	Widau RC (2010), Widau RC (2010), Widau RC (2010)	3
SVIL	9	NR3C1	2	two hybrid	Ting HJ (2002)	1
MIB1	5	DAPK1	6	affinity chromatography technology	Henshall DC (2004)	1
PPP2CA	7	PPP2R5A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Goudreault M (2009), Goudreault M (2009), McCright B (1996), McCright B (1996), Widau RC (2010), Wan C (2015), Hein MY (2015), Craney A (2016), St-Denis N (2016), Yadav L (2017)	10
MDM2	2	YWHAQ	0	affinity chromatography technology, pull down, affinity chromatography technology	Pereg Y (2006), Wang B (2010), Wang B (2010)	3
PPP2CA	7	TP53	0	affinity chromatography technology	Shouse GP (2011)	1
DAPK1	6	SVIL	9	affinity chromatography technology	So J (2015)	1
DAPK1	6	HSP90AA1	7	affinity chromatography technology	Zhang L (2007)	1
ERP44	1	DAPK1	6	affinity chromatography technology	Huttlin EL (2017)	1
CAPZA2	1	SVIL	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
55844	0	PPP2R5A	2	affinity chromatography technology, affinity chromatography technology	Widau RC (2010), Widau RC (2010)	2
CAPZA2	1	TPM3	0	affinity chromatography technology	Hein MY (2015)	1
DAPK1	6	CAPZA2	1	affinity chromatography technology	So J (2015)	1
EEF2	11	YWHAQ	0	biochemical	Kristensen AR (2012)	1
LNX1	7	DAPK1	6	pull down	Wolting CD (2011)	1
TP53	0	PPP2R1A	8	imaging technique, affinity chromatography technology	Chen TC (2014), Kikuchi J (2003)	2
UNC5B	8	PPP2R1B	4	affinity chromatography technology, two hybrid, affinity chromatography technology	Guenebeaud C (2010), Guenebeaud C (2010), Guenebeaud C (2010)	3
DAPK1	6	TMOD3	0	affinity chromatography technology	So J (2015)	1
55844	0	BAG2	0	affinity chromatography technology, affinity chromatography technology	Glatter T (2009), Yadav L (2017)	2
UNC5B	8	DAPK1	6	two hybrid, affinity chromatography technology	Guenebeaud C (2010), Llambi F (2005)	2
MAPK3	4	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Persons DL (2000), How PC (2011), Lin C (2011), Lin C (2011)	4
PDCD6	2	CUL3	17	affinity chromatography technology, pull down, pull down	McGourty CA (2016), McGourty CA (2016), McGourty CA (2016)	3
NR3C1	2	MDM2	2	affinity chromatography technology	Sengupta S (2001)	1
MAPK1	1	TP53	0	affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, imaging technique	Persons DL (2000), How PC (2011), Srivastav RK (2011), Fogeron ML (2013), Chen TC (2014)	5
TNFRSF1A	3	IKBKG	0	affinity chromatography technology, affinity chromatography technology	Zhang SQ (2000), Nakazawa S (2016)	2
MDM2	2	EEF2	11	affinity chromatography technology	Jacob AG (2014)	1
NR3C1	2	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Sengupta S (2000), Sengupta S (2001), Sengupta S (2001), Sengupta S (2001)	4
KRIT1	1	DAPK1	6	affinity chromatography technology	Henshall DC (2003)	1
LRRK2	5	MYL12B	0	affinity chromatography technology	Meixner A (2011)	1
DAPK1	6	UNC5C	1	affinity chromatography technology	Llambi F (2005)	1
HSP90AA1	7	LRRK2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ding X (2009), Ding X (2009), Nichols RJ (2010), Zach S (2010), Daechsel JC (2007), Wang L (2008), Sen S (2009), Rudenko IN (2012), Gloeckner CJ (2006), Imai Y (2015)	10
MAPK3	4	MAPK1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), Wang J (2009), Wang J (2009), Wan C (2015), Hu B (2006)	6
DAPK1	6	DAPK1	6	affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study	Klein CL (2009), de Diego I (2010), Zalckvar E (2009), Widau RC (2010)	4
YWHAQ	0	MYL12B	0	affinity chromatography technology	Pozuelo-Rubio M (2010)	1
LRRK2	5	TPM3	0	affinity chromatography technology	Meixner A (2011)	1
DAPK1	6	MYL12B	0	enzymatic study	Chen CH (2005)	1
LRRK2	5	YWHAQ	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nichols RJ (2010), Nichols RJ (2010), Rudenko IN (2012)	3
HSP90AA1	7	LNX1	7	affinity chromatography technology	Taipale M (2012)	1
HSP90AA1	7	BECN1	2	affinity chromatography technology	Xu C (2011)	1
CUL3	17	LRRK1	12	affinity chromatography technology	Wimuttisuk W (2014)	1
LRRK2	5	FADD	1	affinity chromatography technology	Ho CC (2009)	1
DAPK1	6	EEF2	11	affinity chromatography technology	So J (2015)	1
CAPZA2	1	TWF1	2	affinity chromatography technology	Hein MY (2015)	1
LNX1	7	TSC2	17	two hybrid	Guo Z (2012)	1
TP53	0	EEF2	11	affinity chromatography technology	Yin X (2003)	1
DAPK1	6	DDX5	2	affinity chromatography technology	So J (2015)	1
TNFRSF1A	3	DAPK1	6	affinity chromatography technology	Henshall DC (2003)	1
CUL3	17	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
TMOD3	0	SVIL	9	affinity chromatography technology	Huttlin EL (2017)	1
DAPK1	6	IFI30	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	So J (2015), Huttlin EL (2015), Huttlin EL (2017)	3
IKBKG	0	FADD	1	affinity chromatography technology	Biton S (2011)	1
MDM2	2	HSP90AA1	7	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, biochemical, unspecified method, affinity chromatography technology	Lu TL (2010), Burch L (2004), Burch L (2004), Burch L (2004), Burch L (2004), Burch LR (2004), Okoro DR (2013)	7
DAPK1	6	TSC2	17	affinity chromatography technology	Lin Y (2011)	1
LRRK2	5	PPP2R1A	8	affinity chromatography technology	Liu Z (2011)	1
FADD	1	DAPK1	6	affinity chromatography technology, affinity chromatography technology, imaging technique	Henshall DC (2003), Henshall DC (2004), Chen TC (2014)	3
BECN1	2	TSC1	4	affinity chromatography technology, fluorescent resonance energy transfe	Behrends C (2010), Ivanov AA (2017)	2
CAPZB	2	TMOD3	0	biochemical	Wan C (2015)	1
DAPK1	6	MAPK1	1	two hybrid, pull down, affinity chromatography technology, enzymatic study	Chen CH (2005), Chen CH (2005), Chen CH (2005), Chen CH (2005)	4
DAPK1	6	TWF1	2	affinity chromatography technology	So J (2015)	1
LNX1	7	PPP2R1A	8	affinity chromatography technology	Lenihan JA (2017)	1
DAPK1	6	CORO1C	2	affinity chromatography technology	So J (2015)	1
DAPK1	6	CCNDBP1	0	affinity chromatography technology, affinity chromatography technology	Zhang L (2007), Zhang L (2007)	2
TSC1	4	DAPK1	6	affinity chromatography technology	Lin Y (2011)	1
CUL3	17	YWHAQ	0	affinity chromatography technology	Bennett EJ (2010)	1
SVIL	9	HSP90AA1	7	two hybrid	Smith TC (2010)	1
DAPK1	6	BECN1	2	enzymatic study, pull down, affinity chromatography technology	Zalckvar E (2009), Zalckvar E (2009), Zalckvar E (2009)	3
NR3C1	2	DAPK1	6	protein complementation assay	Lievens S (2016)	1
PPP2CA	7	55844	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Goudreault M (2009), Glatter T (2009), Glatter T (2009), Oberg EA (2012), Widau RC (2010), Wan C (2015), St-Denis N (2016), Huttlin EL (2017), Yadav L (2017), Yadav L (2017), Yadav L (2017)	11
MDM2	2	DDX5	2	affinity chromatography technology	Okoro DR (2013)	1
IVNS1ABP	0	DAPK1	6	affinity chromatography technology	Chen HY (2015)	1
LRRK2	5	MYO1D	3	affinity chromatography technology, affinity chromatography technology	Meixner A (2011), Meixner A (2011)	2
FADD	1	TNFRSF1A	3	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gajate C (2005), Hsu H (1996), Kumar A (2001), Zheng L (2006)	4
TSC2	17	TSC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dan HC (2002), Hodges AK (2001), Aicher LD (2001), van Slegtenhorst M (1998), Nellist M (2002), Li Y (2004), Mak BC (2003), van Slegtenhorst M (1998), van Slegtenhorst M (1998), Ma L (2005), Cai SL (2006), Cao Y (2006), Ma L (2005), Inoki K (2003), Nellist M (2005), Goncharova EA (2006), Astrinidis A (2006), Cao Y (2006), Astrinidis A (2003), Hodges AK (2001), Hodges AK (2001), Nellist M (2001), Aicher LD (2001), Murthy V (2000), van Slegtenhorst M (1998), Dan HC (2002), Miloloza A (2000), Nakashima A (2007), Nakashima A (2007), Benvenuto G (2000), Chong-Kopera H (2006), York B (2005), Vega-Rubin-de-Celis S (2010), Vega-Rubin-de-Celis S (2010), Lin Y (2011), Cloutier P (2017), Cloutier P (2017)	37
IKBKG	0	PPP2R1B	4	affinity chromatography technology	Griffiths DA (2013)	1
CUL3	17	PPP2CA	7	affinity chromatography technology	Bennett EJ (2010)	1
LRRK2	5	CAPZA2	1	affinity chromatography technology	Meixner A (2011)	1
YWHAQ	0	DAPK1	6	affinity chromatography technology	Henshall DC (2003)	1
KLHL20	2	DAPK1	6	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Lee YR (2010), Lee YR (2010), Lee YR (2010), Chen HY (2015)	4
PPP2R1A	8	DAPK1	6	enzymatic study	Widau RC (2010)	1
LRRK2	5	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Ho DH (2015), Ho DH (2015), Ho DH (2015)	3
CUL3	17	CALM1	0	affinity chromatography technology	Bennett EJ (2010)	1
MAPK3	4	PPP2CA	7	affinity chromatography technology	Quevedo C (2003)	1
MAPK1	1	TNFRSF1A	3	enzymatic study, affinity chromatography technology, pull down	Frankel SK (2001), Ibeas E (2009), Ibeas E (2009)	3
KLHL20	2	CUL3	17	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Lee YR (2010), Bennett EJ (2010), Yuan WC (2014), Chen HY (2015), Chen HY (2015), Huttlin EL (2017)	6
HSP90AA1	7	BAG2	0	affinity chromatography technology	Gano JJ (2010)	1
PPP2R1A	8	PPP2R1B	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Goudreault M (2009), Sablina AA (2007), Fogeron ML (2013), Wan C (2015), Hein MY (2015)	5
PPP2R1A	8	PPP2R5A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, bioid	Goudreault M (2009), Goudreault M (2009), Zhou J (2003), Zhou J (2003), Widau RC (2010), Wan C (2015), Hein MY (2015), Yadav L (2017), Yadav L (2017)	9
LNX1	7	PPP2CA	7	affinity chromatography technology	Lenihan JA (2017)	1
CALM1	0	DAPK1	6	affinity chromatography technology, x-ray crystallography, pull down	Henshall DC (2004), de Diego I (2010), de Diego I (2010)	3
NR3C1	2	HSP90AA1	7	imaging technique, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down	Jibard N (1999), Hulkko SM (2000), Kanelakis KC (2002), Hecht K (1997), de Castro M (1996), van den Berg JD (1996), Stancato LF (1996), Kovacs JJ (2005), Silverstein AM (1997), Gradin K (1994), Gano JJ (2010), Miyamoto-Sato E (2010), Mollapour M (2014), Moraes LA (2005), Wochnik GM (2004), Woodford MR (2016), Lievens S (2016), McGuire J (1994)	18
DAPK1	6	MAPK3	4	two hybrid, pull down, affinity chromatography technology, imaging technique	Chen CH (2005), Chen CH (2005), Chen CH (2005), Chen TC (2014)	4
PPP2CA	7	PPP2R1A	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, bioid	Goudreault M (2009), Goudreault M (2009), Zhou J (2003), Zhou J (2003), Glatter T (2009), Glatter T (2009), Sablina AA (2007), Sablina AA (2007), Kong M (2009), Kong M (2009), Shamay M (2012), Havugimana PC (2012), Junttila MR (2007), Junttila MR (2007), Nazarenko I (2007), Kristensen AR (2012), Fogeron ML (2013), Sablina AA (2010), Lee CW (2014), Wan C (2015), Hein MY (2015), Hein MY (2015), Cianfanelli V (2015), St-Denis N (2016), Bryant JC (1999), Shouse GP (2011), Yadav L (2017), Yadav L (2017), Yadav L (2017), Yadav L (2017)	30
YWHAQ	0	CALM1	0	affinity chromatography technology, pull down, biochemical	Pozuelo-Rubio M (2010), Meek SE (2004), Pozuelo-Rubio M (2010)	3
PPP2R1A	8	55844	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, bioid	Goudreault M (2009), Glatter T (2009), Glatter T (2009), Widau RC (2010), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016), Yadav L (2017), Yadav L (2017), Yadav L (2017), Yadav L (2017)	12
CAPZA2	1	CAPZB	2	biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	5
IKBKG	0	DAPK1	6	pull down	Fenner BJ (2010)	1
PDCD6	2	DAPK1	6	two hybrid, affinity chromatography technology	Lee JH (2005), Lee JH (2005)	2