PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
COPS3	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Min KW (2005), Enchev RI (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	9
HIST1H3A	3	DDB1	6	affinity chromatography technology, pull down	Higa LA (2006), Higa LA (2006)	2
DTL	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Higa LA (2006), Higa LA (2006), Sertic S (2013), Shibata E (2014), Hein MY (2015), Shibata E (2011), Higa LA (2006), Higa LA (2006)	9
DCUN1D1	0	PHIP	20	affinity chromatography technology	Bennett EJ (2010)	1
DCAF8	1	COPS7A	0	biochemical	Kristensen AR (2012)	1
DDA1	1	DCAF8	1	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
HUWE1	22	UBA1	1	affinity chromatography technology	Thompson JW (2014)	1
CDKN1A	1	HDAC1	4	pull down, affinity chromatography technology, pull down, imaging technique	Li Z (2010), Li Z (2010), Garcia-Wilson E (2005), Chen TC (2014)	4
SIN3A	13	SAP30	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology	Fleischer TC (2003), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Zhang Y (1999), Yochum GS (2001), Kuzmichev A (2002), Kuzmichev A (2002), Kuzmichev A (2002), Laherty CD (1998), Viiri KM (2006), Viiri KM (2006), Nakamura T (2002), Lai A (2001), Skowyra D (2001), Zhang Y (1998), Zhang Y (1998), Xie T (2011), Xie T (2011), Bantscheff M (2011), Hein MY (2015)	21
COPS8	2	COPS7A	0	biochemical, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Huang X (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
CDT1	2	FZR1	1	affinity chromatography technology, pull down	Sugimoto N (2008), Sugimoto N (2008)	2
PYGO2	1	KAT2A	1	affinity chromatography technology, pull down	Chen J (2010), Chen J (2010)	2
DDA1	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Jin J (2006), Hein MY (2015)	3
NF2	1	RBBP4	3	affinity chromatography technology	Zhou L (2015)	1
COPS5	0	UBA1	1	affinity chromatography technology	Bennett EJ (2010)	1
BRCA1	7	10607	0	affinity chromatography technology	Ertych N (2016)	1
BRCA1	7	AHR	3	affinity chromatography technology, affinity chromatography technology, pull down	Kang HJ (2008), Kang HJ (2008), Kang HJ (2008)	3
DCAF1	5	CUL4A	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ahn J (2010), Belzile JP (2007), He YJ (2006), McCall CM (2008), McCall CM (2008), McCall CM (2008), McCall CM (2008), Hrecka K (2007), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006), Kyei GB (2015)	14
UCHL1	1	COPS5	0	two hybrid, affinity chromatography technology	Caballero OL (2002), Caballero OL (2002)	2
DDB1	6	COPS6	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Emberley ED (2012), Bennett EJ (2010), Olma MH (2009)	5
WDTC1	1	CUL4B	8	affinity chromatography technology	Huttlin EL (2017)	1
EP300	36	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pao GM (2000), Pao GM (2000), Pao GM (2000), Pao GM (2000), Fan S (2002), Fan S (2002), Ma Y (2010), Subbaramaiah K (2011), Subbaramaiah K (2012)	9
ATXN3	2	CHEK1	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Tu Y (2017), Tu Y (2017), Tu Y (2017), Tu Y (2017), Tu Y (2017)	5
DCUN1D1	0	COPS3	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL4A	2	CRBN	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Ito T (2010), Bennett EJ (2010), Liu Y (2015), Liu Y (2015), Diaz-Rodriguez E (2016), Xu Q (2016), Xu G (2013), Nguyen TV (2016), Nguyen TV (2016), Eichner R (2016), Eichner R (2016), Huttlin EL (2017), Kroenke J (2014)	14
MDM2	2	ERCC8	1	affinity chromatography technology	Latini P (2011)	1
GPS1	1	COPS2	5	affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, two hybrid, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Stotland A (2012), Huang X (2005), Sharon M (2009), Kapelari B (2000), Tsuge T (2001), Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
COPS2	5	DCAF4	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ERCC6	6	CUL4A	2	affinity chromatography technology	Latini P (2011)	1
COPS6	0	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sowa ME (2009), Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Birol M (2014)	5
DDB2	1	HDAC1	4	affinity chromatography technology, affinity chromatography technology	Zhao R (2014), Zhu Q (2015)	2
SUPT3H	4	DDB1	6	affinity chromatography technology, affinity chromatography technology, pull down	Martinez E (2001), Martinez E (2001), Martinez E (2001)	3
COPS8	2	DCAF4	3	affinity chromatography technology	Huttlin EL (2017)	1
CUL4B	8	DCAF16	0	affinity chromatography technology	Bennett EJ (2010)	1
SIRT7	1	HUWE1	22	affinity chromatography technology	Tsai YC (2012)	1
DCAF4L2	3	COPS2	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Wang H (2016)	2
CUL4A	2	MDM2	2	affinity chromatography technology, affinity chromatography technology	Banks D (2006), Latini P (2011)	2
DDB1	6	AHR	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kawajiri K (2009), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007)	4
COPS3	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Kristensen AR (2012), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
COPS5	0	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	11
COPS7A	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Hein MY (2015), Huttlin EL (2017)	3
DDB1	6	WDTC1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Jin J (2006), Huttlin EL (2017)	4
DDB1	6	COPS7B	0	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006)	2
SAP130	2	SUDS3	3	affinity chromatography technology	Fleischer TC (2003)	1
COPS4	0	COPS7B	0	affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	7
SUV39H1	0	DNMT3A	17	pull down, affinity chromatography technology	Fuks F (2003), Fuks F (2003)	2
CUL4B	8	SIN3A	13	affinity chromatography technology, affinity chromatography technology, pull down, biochemical	Ji Q (2014), Ji Q (2014), Ji Q (2014), Ji Q (2014)	4
COPS4	0	CRBN	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Kroenke J (2014)	2
DDB1	6	DCAF10	2	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006)	2
DDB2	1	EP300	36	affinity chromatography technology, affinity chromatography technology	Datta A (2001), Rapic-Otrin V (2002)	2
DDB1	6	UCHL1	1	affinity chromatography technology, affinity chromatography technology	Hussain S (2013), Hussain S (2013)	2
CUL4B	8	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Jin J (2006), Wang H (2006), Higa LA (2006), Higa LA (2006), Kawajiri K (2009), Bennett EJ (2010), Havugimana PC (2012), Ji Q (2014), Wan C (2015), Hein MY (2015), Mo Y (2017), Mo Y (2017), Yang Y (2015), Yang Y (2015), Yang Y (2015), Higa LA (2006), Higa LA (2006), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007)	23
COPS7A	0	DCAF4	3	affinity chromatography technology	Hein MY (2015)	1
HUWE1	22	RASSF1	3	affinity chromatography technology	Zhou X (2012)	1
SUPT3H	4	SAP130	2	affinity chromatography technology	Holmlund T (2012)	1
DDB1	6	COPS2	5	affinity chromatography technology, affinity chromatography technology, pull down	Angers S (2006), Jin J (2006), Emberley ED (2012)	3
HIST1H1A	0	DDB1	6	affinity chromatography technology, affinity chromatography technology	Kim K (2013), Kim K (2013)	2
DCAF8	1	COPS2	5	affinity chromatography technology	Olma MH (2009)	1
COPS7A	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uhle S (2003), Bennett EJ (2010), Huang X (2016), Reitsma JM (2017)	4
UBC	7	COPS4	0	affinity chromatography technology	Matsumoto M (2005)	1
CEP78	2	DDB1	6	affinity chromatography technology, affinity chromatography technology	Hossain D (2017), Hossain D (2017)	2
UVRAG	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Yang Y (2016), Yang Y (2016)	2
GRK5	7	DCAF5	1	affinity chromatography technology	Wu Z (2012)	1
UBC	7	GNB2	3	affinity chromatography technology	Matsumoto M (2005)	1
DDB1	6	PHIP	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Angers S (2006), Jin J (2006), Jin J (2006), Wan C (2015)	4
COPS6	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Kristensen AR (2012), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
CDT1	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology	Hu J (2004), Hu J (2004), Hu J (2004), Hu J (2004), Zhang Y (2012)	5
CRBN	2	COPS7B	0	affinity chromatography technology	Kroenke J (2014)	1
CUL4B	8	PHIP	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Jin J (2006), Hein MY (2015)	3
DDB1	6	UBC	7	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Matsumoto M (2005)	2
HIST1H3A	3	HDAC2	1	affinity chromatography technology, enzymatic study, pull down	Nishioka K (2002), Gyoery I (2003), Li X (2014)	3
RPTOR	4	DDB1	6	affinity chromatography technology, affinity chromatography technology	Hussain S (2013), Hussain S (2013)	2
ATXN3	2	DDB1	6	affinity chromatography technology, affinity chromatography technology	Tu Y (2017), Tu Y (2017)	2
RBBP4	3	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang Y (2003), Hakimi MA (2003), Zhang Y (2002), Tong JK (1998), Sun JM (2007), Sun JM (2007), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Wan C (2015), Hauri S (2016)	14
DCAF11	2	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	3
RAG1	1	UBC	7	enzymatic study	Yurchenko V (2003)	1
CUL4A	2	DCUN1D1	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010), Monda JK (2013), Meyer-Schaller N (2009), Kim AY (2008), Kim AY (2008), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	9
BRCA1	7	HDAC2	1	pull down, affinity chromatography technology, genetic interference	Yarden RI (1999), Chang S (2011), Shen JP (2017)	3
SAP130	2	CUL4A	2	affinity chromatography technology	Menon S (2008)	1
NEDD8	0	COPS2	5	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
DDB1	6	DCAF5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Jin J (2006)	3
ERCC8	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Olma MH (2009)	3
GRK5	7	COPS7A	0	affinity chromatography technology	Wu Z (2012)	1
DCUN1D1	0	COPS6	0	affinity chromatography technology	Bennett EJ (2010)	1
SIRT7	1	10607	0	affinity chromatography technology	Tsai YC (2012)	1
COPS3	1	COPS7B	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Enchev RI (2010), Olma MH (2009), Havugimana PC (2012), Huttlin EL (2015), Huang X (2016), Huttlin EL (2017)	6
HUWE1	22	RBBP4	3	affinity chromatography technology	Thompson JW (2014)	1
DCUN1D1	0	COPS8	2	affinity chromatography technology	Bennett EJ (2010)	1
MDM2	2	UBC	7	pull down, enzymatic study, enzymatic study	Higashitsuji H (2005), Luo J (2013), Poyurovsky MV (2007)	3
FZR1	1	DDB1	6	affinity chromatography technology, affinity chromatography technology	Lv XB (2010), Lv XB (2010)	2
TP73	2	CUL1	7	affinity chromatography technology	Peschiaroli A (2009)	1
CUL4A	2	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Bennett EJ (2010), Sertic S (2013), Rossi M (2013), Jin J (2006), Shibata E (2011), Higa LA (2006)	7
CUL4A	2	TRPC4AP	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Choi SH (2010), Bennett EJ (2010), Huttlin EL (2017)	4
HIST1H1C	2	RBX1	2	affinity chromatography technology, pull down	Kim K (2013), Kim K (2013)	2
CUL4A	2	DCAF16	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Jin J (2006)	3
RFWD2	0	DDB2	1	affinity chromatography technology	Olma MH (2009)	1
LIG1	4	DDB1	6	affinity chromatography technology, affinity chromatography technology	Peng Z (2016), Peng Z (2016)	2
SAP30	1	SAP130	2	affinity chromatography technology	Hein MY (2015)	1
DDB1	6	BRWD1	6	affinity chromatography technology, biochemical	Angers S (2006), Wan C (2015)	2
ARID4B	1	SAP30	1	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
UBC	7	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Matsumoto M (2005), Bennett EJ (2010), Bish RA (2007), Wu K (2016)	4
EP300	36	UBC	7	enzymatic study, affinity chromatography technology	Delvecchio M (2013), Kirilyuk A (2012)	2
DDA1	1	DCAF10	2	affinity chromatography technology	Olma MH (2009)	1
DET1	2	MDM2	2	affinity chromatography technology	Pick E (2007)	1
SIRT7	1	CUL4A	2	affinity chromatography technology	Mo Y (2017)	1
CUL4B	8	10607	0	affinity chromatography technology, pull down	Ohtake F (2007), Ohtake F (2007)	2
TP73	2	HDAC2	1	affinity chromatography technology	Zhang J (2007)	1
INO80	5	ACTR5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Kumeta M (2010), Chen L (2011), Cai Y (2007), Jiang Y (2010), Jiang Y (2010), Wan C (2015), Hein MY (2015)	7
COPS5	0	DCAF16	0	affinity chromatography technology	Bennett EJ (2010)	1
DCAF4L2	3	GPS1	1	affinity chromatography technology	Wang H (2016)	1
COPS2	5	COPS4	0	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Huang X (2005), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	8
DTL	0	COPS2	5	affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Higa LA (2006)	2
DDB1	6	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Angers S (2006), Jin J (2006), Min KW (2005), Emberley ED (2012), Olma MH (2009)	5
UBA1	1	CHEK1	2	pull down	Tan X (2015)	1
CUL1	7	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	BRWD1	6	affinity chromatography technology	Bennett EJ (2010)	1
DDB2	1	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, imaging technique	Kapetanaki MG (2006), Takedachi A (2010), Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Matsumoto S (2015), Hein MY (2015), Groisman R (2006), Groisman R (2006), Chitale S (2017)	10
COPS6	0	COPS4	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sharon M (2009), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	14
COPS5	0	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Stotland A (2012), Bennett EJ (2010), Oh W (2006), Chun Y (2013), Chun Y (2013), Chun Y (2013), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
DDA1	1	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	4
DET1	2	COPS5	0	affinity chromatography technology	Huttlin EL (2017)	1
COPS5	0	CDT1	2	biochemical	He YJ (2006)	1
HDAC1	4	SIN3A	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Yao YL (2003), Yao YL (2003), Fleischer TC (2003), Fleischer TC (2003), Yang L (2003), Grozinger CM (1999), Zhang J (2002), Zhang J (2002), You A (2001), Zhang Y (1999), Zhang Y (2002), Tong JK (1998), Hassig CA (1998), Yasui D (2002), Huang EY (2000), Huang EY (2000), Kuzmichev A (2002), Kuzmichev A (2002), Martinowich K (2003), Martinowich K (2003), Suzuki M (2003), Suzuki M (2006), Nakamura T (2002), Wei Q (2005), Pflum MK (2001), Pflum MK (2001), Skowyra D (2001), Skowyra D (2001), Humphrey GW (2001), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Sun JM (2007), Karwowska-Desaulniers P (2007), Terhune SS (2010), Xue Y (1998), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Oh YM (2009), Wan C (2015), Hein MY (2015), Hsu DS (2014), Huttlin EL (2017)	45
MTOR	14	RPTOR	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jacinto E (2004), Jacinto E (2004), Sarbassov DD (2004), Sarbassov DD (2004), Sarbassov DD (2004), Schalm SS (2003), Hara K (2002), Ha SH (2006), Wang L (2006), Frias MA (2006), Frias MA (2006), Buerger C (2006), Jacinto E (2006), McMahon LP (2005), Oshiro N (2004), Kawai S (2003), Choi KM (2003), Hara K (2002), Hara K (2002), Kim DH (2002), Kim DH (2002), Schieke SM (2006), Ha SH (2006), Wang L (2006), Frias MA (2006), Buerger C (2006), Sarbassov DD (2006), Tzatsos A (2006), Sarbassov DD (2005), Yang Q (2006), Kaizuka T (2010), Pearce LR (2007), Oh WJ (2010), Oh WJ (2010), Agrawal P (2012), Kwak D (2012), Wu D (2012), Wu D (2012), Wu D (2012), Wu D (2012), Gwinn DM (2010), Sancak Y (2007), Sancak Y (2007), Yang Q (2006), Carriere A (2011), Jacinto E (2006), Rosner M (2010), Kim DH (2003), Kim DH (2003), Carriere A (2008), Murata H (2011), Koike-Kumagai M (2009), Koike-Kumagai M (2009), Hussain S (2013), Hussain S (2013), Peterson TR (2009), Peterson TR (2009), Su WC (2009), Hernandez-Negrete I (2007), Yan X (2012), Ramirez-Rangel I (2011), Ramirez-Rangel I (2011), Martin J (2008), Martin J (2008), Linares JF (2013), Coffman K (2014), Oshiro N (2014), Thedieck K (2007), Thedieck K (2007), Thedieck K (2007), Dan HC (2008), Dan HC (2008), Dan HC (2008), Hong F (2008), Hong F (2008), Choo AY (2008), Toschi A (2009), Loewith R (2002), Xu Y (2013), Sancak Y (2010), Sancak Y (2010), Vander Haar E (2007), Vander Haar E (2007), Kaadige MR (2015), Misra UK (2014), Misra UK (2014), Thedieck K (2007), Thomas JD (2014), Park D (2014), Alayev A (2016), Alayev A (2016)	91
DCUN1D1	0	DCAF1	5	affinity chromatography technology	Bennett EJ (2010)	1
CUL4B	8	COPS8	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	4
CUL4B	8	HDAC2	1	affinity chromatography technology, affinity chromatography technology, biochemical	Ji Q (2014), Ji Q (2014), Ji Q (2014)	3
COPS5	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Min KW (2005), Chua YS (2011), Boh BK (2011), Emberley ED (2012), Emberley ED (2012), Choo YY (2011), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Enchev RI (2012), Birol M (2014), Pick E (2012), Sharon M (2009), Enchev RI (2012), Bornstein G (2015), Rockel B (2014), Schlierf A (2016), Reitsma JM (2017), Reitsma JM (2017)	23
EP300	36	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Han Y (2008), Mayanil CS (2006), Simone C (2004), Simone C (2004), Simone C (2004), Liu Y (2012), Mizuguchi Y (2012)	7
CHEK1	2	FZR1	1	genetic interference	Srivas R (2016)	1
DCAF8	1	COPS3	1	affinity chromatography technology	Olma MH (2009)	1
SUV39H1	0	HIST1H3A	3	enzymatic study, enzymatic study, enzymatic study	Carbone R (2006), Kamoi K (2006), Mal AK (2006)	3
UBC	7	NEDD8	0	affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography	Matsumoto M (2005), Bennett EJ (2010), Singh RK (2012), Singh RK (2012)	4
DDA1	1	DCAF15	3	affinity chromatography technology	Olma MH (2009)	1
ARID4B	1	SUDS3	3	affinity chromatography technology	Fleischer TC (2003)	1
DET1	2	RFWD2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Wertz IE (2004), Vitari AC (2011), Lu G (2014), Lu G (2014), Pick E (2007), Huttlin EL (2017)	7
COPS8	2	COPS3	1	biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Min KW (2005), Enchev RI (2010), Sharon M (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	11
ACTR5	1	DDB1	6	affinity chromatography technology, affinity chromatography technology	Jiang Y (2010), Jiang Y (2010)	2
EP300	36	HIST1H1A	0	enzymatic study, enzymatic study	Loven MA (2004), Sakaguchi K (1998)	2
COPS8	2	COPS2	5	biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Yang X (2002), Huang X (2005), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	9
CUL4A	2	DDA1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Pick E (2007), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006)	7
RBX1	2	CUL4B	8	affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, imaging technique	Dias DC (2002), Ji Q (2014), Huang DT (2009), Hein MY (2015), Yang Y (2015)	5
NEDD8	0	COPS8	2	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D1	0	CUL1	7	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Kim AY (2008), Wu K (2011), Bennett EJ (2010), Huang G (2011), Monda JK (2013), Bommelje CC (2013), Meyer-Schaller N (2009), Kim AY (2008), Kim AY (2008), Huang G (2014), Huang G (2014), Huang G (2014), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	16
DET1	2	COPS6	0	affinity chromatography technology	Huttlin EL (2017)	1
AHR	3	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Ohtake F (2007), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007)	5
COPS5	0	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), McCall CM (2008), Bennett EJ (2010), Olma MH (2009)	4
ERCC8	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down	Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Fei J (2012), Jin J (2006), He J (2016), Groisman R (2006), Groisman R (2006)	8
CDKN1A	1	GNB2	3	two hybrid	Vinayagam A (2011)	1
MUS81	1	INO80	5	genetic interference	Vizeacoumar FJ (2013)	1
SIRT7	1	HIST1H1A	0	affinity chromatography technology	Tsai YC (2012)	1
MDM2	2	SUV39H1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen L (2010), Mungamuri SK (2016), Mungamuri SK (2016)	3
DDB1	6	DCAF11	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Angers S (2006), Jin J (2006), He YJ (2006), Olma MH (2009), Jin J (2006), Huttlin EL (2017), Lo JY (2017)	8
COPS6	0	DDB2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Kulaksiz G (2005), Olma MH (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
DYRK2	1	DCAF5	1	affinity chromatography technology	Maddika S (2009)	1
AHR	3	RBX1	2	affinity chromatography technology	Ohtake F (2007)	1
COPS5	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Sertic S (2013), Higa LA (2006), Higa LA (2006)	5
RFWD2	0	COPS7B	0	affinity chromatography technology	Olma MH (2009)	1
HDAC1	4	HDAC2	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology	Hakimi MA (2002), Yao YL (2003), Yao YL (2003), Hakimi MA (2003), Fischle W (2002), Johnson CA (2002), Fischle W (2001), Fischer DD (2002), Fischer DD (2002), Ashburner BP (2001), Zhang Y (1999), Tong JK (1998), Tong JK (1998), Hassig CA (1998), Hassig CA (1998), Zhang Y (1997), van der Vlag J (1999), van der Vlag J (1999), Noh EJ (2009), Noh EJ (2009), Galasinski SC (2002), Galasinski SC (2002), Galasinski SC (2002), He S (2005), Humphrey GW (2001), Park JH (2004), Park JH (2004), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Martinez FP (2012), Martinez FP (2012), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Joshi P (2013), Schnur N (2007), Schnur N (2007), Oh YM (2009), Wan C (2015), Hein MY (2015), Chen TC (2014), Huttlin EL (2017)	48
CUL4A	2	DDB2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Kapetanaki MG (2006), Matsuda N (2005), Higa LA (2006), Nag A (2001), Takedachi A (2010), Fischer ES (2011), Tan L (2007), He YJ (2006), He YJ (2006), Groisman R (2003), Groisman R (2003), Hrecka K (2007), Shiyanov P (1999), Shiyanov P (1999), Bennett EJ (2010), Kulaksiz G (2005), Kulaksiz G (2005), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006), Groisman R (2003), Huttlin EL (2015), Hein MY (2015), Groisman R (2006), Yang Y (2016), Huttlin EL (2017), Fantini D (2017)	31
IP6K1	5	DDB1	6	affinity chromatography technology, pull down	Rao F (2014), Rao F (2014)	2
COPS3	1	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Yang X (2002), Enchev RI (2010), Huang X (2005), Kapelari B (2000), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Rozen S (2015), Huttlin EL (2017)	13
CRBN	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xu Q (2016), Eichner R (2016), Huttlin EL (2017), Kroenke J (2014)	4
MCM10	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kaur M (2012), Kaur M (2012), Romani B (2015)	3
DDA1	1	DCAF17	0	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Olma MH (2009)	2
CDT1	2	CUL1	7	affinity chromatography technology	Li X (2003)	1
NEDD8	0	COPS7B	0	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D1	0	COPS7B	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS4	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Shibata E (2011), Higa LA (2006)	3
SIRT7	1	DCAF11	2	affinity chromatography technology	Mo Y (2017)	1
DCAF1	5	RBX1	2	pull down	Ahn J (2010)	1
HIST1H3A	3	ERCC6	6	affinity chromatography technology, affinity chromatography technology, far western blotting	Citterio E (2000), Citterio E (2000), Citterio E (2000)	3
DDA1	1	DCAF5	1	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Olma MH (2009)	2
UVRAG	2	DDB1	6	affinity chromatography technology, affinity chromatography technology	Yang Y (2016), Yang Y (2016)	2
DDB1	6	DDA1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Angers S (2006), Behrends C (2010), Pick E (2007), Pick E (2007), Hrecka K (2007), Hrecka K (2007), Olma MH (2009), Olma MH (2009), Jin J (2006), Wan C (2015)	10
HUWE1	22	STAT1	1	affinity chromatography technology	Thompson JW (2014)	1
COPS6	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Reitsma JM (2017)	7
DDB1	6	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Ji Q (2014), Ji Q (2014), Zhao R (2014), Romani B (2016)	4
CUL4A	2	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Angers S (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Rao F (2014), Rao F (2014), Huttlin EL (2015), Cavadini S (2016), Scherer PC (2016), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	13
ARID4B	1	HDAC2	1	affinity chromatography technology, affinity chromatography technology	Fleischer TC (2003), Joshi P (2013)	2
RAG1	1	DCAF1	5	biochemical, pull down, affinity chromatography technology	Kassmeier MD (2011), Kassmeier MD (2011), Kassmeier MD (2011)	3
SUPT3H	4	DDB2	1	affinity chromatography technology	Martinez E (2001)	1
HIST1H3A	3	CUL4A	2	affinity chromatography technology, pull down	Higa LA (2006), Higa LA (2006)	2
CRBN	2	COPS7A	0	affinity chromatography technology	Kroenke J (2014)	1
COPS5	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Olma MH (2009), Rao F (2014), Pick E (2012), Groisman R (2003), Groisman R (2003), Huttlin EL (2015), Cavadini S (2016), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	19
DYRK2	1	MDM2	2	affinity chromatography technology, enzymatic study, affinity chromatography technology	Taira N (2010), Taira N (2010), Taira N (2010)	3
BRCA1	7	UBA1	1	affinity chromatography technology	Ertych N (2016)	1
MTOR	14	GNB2	3	affinity chromatography technology	Robles-Molina E (2014)	1
EP300	36	RORA	4	two hybrid, pull down	Lau P (1999), Lau P (1999)	2
MTOR	14	DDB1	6	affinity chromatography technology, affinity chromatography technology	Hussain S (2013), Hussain S (2013)	2
CUL4A	2	GNB2	3	affinity chromatography technology, affinity chromatography technology	Zha Z (2015), Zha Z (2015)	2
COPS5	0	MDM2	2	affinity chromatography technology, pull down	Zhang XC (2008), Zhang XC (2008)	2
NEDD8	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
DCAF4	3	COPS7B	0	affinity chromatography technology	Huttlin EL (2017)	1
HIST1H1C	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, pull down	Kim K (2013), Kim K (2013), Kim K (2013)	3
GNB2	3	STAT1	1	affinity chromatography technology	Bhatnagar A (2013)	1
IP6K1	5	RBX1	2	affinity chromatography technology	Rao F (2014)	1
MDM2	2	CUL4B	8	affinity chromatography technology	Latini P (2011)	1
RAD21	3	UBA1	1	affinity chromatography technology, affinity chromatography technology	Panigrahi AK (2011), Panigrahi AK (2011)	2
NF2	1	HDAC1	4	affinity chromatography technology	Zhou L (2015)	1
RFWD2	0	DCAF11	2	affinity chromatography technology	Olma MH (2009)	1
MDM2	2	DDB1	6	affinity chromatography technology, affinity chromatography technology	Latini P (2011), Jacob AG (2014)	2
MUS81	1	DDB1	6	affinity chromatography technology, pull down	Zhou X (2016), Zhou X (2016)	2
SAP30	1	SUDS3	3	affinity chromatography technology	Hein MY (2015)	1
RPTOR	4	EP300	36	affinity chromatography technology	Wan W (2017)	1
DDB1	6	UNG	1	pull down, affinity chromatography technology	Ahn J (2010), Wen X (2012)	2
DDB1	6	DCAF12	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Jin J (2006)	3
DDA1	1	COPS2	5	affinity chromatography technology	Olma MH (2009)	1
GRK5	7	DDB2	1	affinity chromatography technology	Wu Z (2012)	1
EP300	36	COPS2	5	enzymatic study, pull down	Eckey M (2013), Eckey M (2013)	2
COPS6	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Higa LA (2006)	4
DCAF4L2	3	DDB1	6	affinity chromatography technology, affinity chromatography technology	Wang H (2016), Wang H (2016)	2
RPTOR	4	AMBRA1	7	affinity chromatography technology	Nazio F (2013)	1
CDKN1A	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe, affinity chromatography technology, imaging technique	Zhang Z (2004), Zhang Z (2004), Zhang Z (2004), Jin Y (2003), Jin Y (2003), Wang B (2010), Xu H (2010), Xu H (2010), Frum R (2007), Chen TC (2014)	10
DTL	0	GPS1	1	affinity chromatography technology	Higa LA (2006)	1
GRK5	7	COPS4	0	affinity chromatography technology	Wu Z (2012)	1
SUPT3H	4	KAT2A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brand M (2001), Martinez E (2001), Martinez E (2001), Liu X (2008), Kim J (2010), Holmlund T (2012), Liu X (2003)	7
COPS7A	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Hein MY (2015)	2
RASSF1	3	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHEK1	2	BRCA1	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, genetic interference	Yarden RI (2002), Yarden RI (2002), Inoue Y (2007), Shen JP (2017)	4
CUL1	7	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Min KW (2005), Lee JE (2011), Bennett EJ (2010), Lyapina S (2001), Reitsma JM (2017)	6
NF2	1	KAT2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
UBC	7	UBA1	1	affinity chromatography technology, unspecified method, x-ray crystallography, biochemical, affinity chromatography technology, pull down	Nicassio F (2007), Zhao B (2012), Schaefer A (2014), Schaefer A (2014), Bish RA (2007), Zhang X (2017)	6
DDB1	6	DCAF16	0	affinity chromatography technology, affinity chromatography technology	Jin J (2006), Jin J (2006)	2
RAG1	1	HIST1H3A	3	enzymatic study	Jones JM (2011)	1
DDB1	6	SAP30	1	affinity chromatography technology, affinity chromatography technology	Ji Q (2014), Ji Q (2014)	2
DCUN1D1	0	COPS2	5	affinity chromatography technology	Bennett EJ (2010)	1
COPS6	0	DCAF8	1	affinity chromatography technology	Olma MH (2009)	1
CUL4A	2	COPS8	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2017), Boldt K (2016)	7
CUL4B	8	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Jin J (2006), Hein MY (2015), Wang X (2017)	4
DET1	2	COPS3	1	affinity chromatography technology	Huttlin EL (2017)	1
NEDD8	0	COPS4	0	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
RAG1	1	RBX1	2	affinity chromatography technology	Kassmeier MD (2011)	1
DDB1	6	GNB2	3	affinity chromatography technology, affinity chromatography technology	Zha Z (2015), Zha Z (2015)	2
RICTOR	4	DDB1	6	affinity chromatography technology, affinity chromatography technology	Hussain S (2013), Hussain S (2013)	2
ERCC6	6	UBC	7	pull down, pull down	Anindya R (2010), Anindya R (2010)	2
CUL4A	2	WDTC1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010), Jin J (2006), Huttlin EL (2017)	4
CUL1	7	COPS8	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Menon S (2008), Bennett EJ (2010), Enchev RI (2012), Reitsma JM (2017)	4
SIRT7	1	PHIP	20	affinity chromatography technology	Tsai YC (2012)	1
COPS3	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Reitsma JM (2017)	4
COPS5	0	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Olma MH (2009), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Bhansali M (2014), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	13
COPS5	0	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Sowa ME (2009), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Groisman R (2006)	5
CUL4B	8	HDAC1	4	affinity chromatography technology, affinity chromatography technology, biochemical	Ji Q (2014), Ji Q (2014), Ji Q (2014)	3
CUL4B	8	DNMT3A	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015)	5
GRK5	7	COPS2	5	affinity chromatography technology	Wu Z (2012)	1
COPS5	0	DCAF12	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS2	5	IP6K1	5	pull down	Rao F (2014)	1
COPS6	0	CRBN	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Olma MH (2009), Kroenke J (2014)	3
ERCC6	6	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Anindya R (2010), Latini P (2011), Latini P (2011)	3
COPS2	5	COPS7B	0	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	7
BRCA1	7	DDB1	6	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
DDB1	6	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Olma MH (2009)	3
CDKN1A	1	HDAC2	1	pull down	Garcia-Wilson E (2005)	1
DYRK2	1	CEP78	2	affinity chromatography technology, affinity chromatography technology	Hossain D (2017), Hossain D (2017)	2
BRCA1	7	RAD21	3	affinity chromatography technology	Hill SJ (2014)	1
COPS8	2	GPS1	1	biochemical, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Stotland A (2012), Sharon M (2009), Sun Y (2002), Kristensen AR (2012), Lingaraju GM (2014), Lyapina S (2001), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	10
DDB1	6	TP73	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Malatesta M (2012), Malatesta M (2012), Malatesta M (2012)	3
NF2	1	DCAF1	5	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology	Huang J (2008), Huang J (2008), Huang J (2008), Huang J (2008), Huang J (2008), Li W (2010), Li W (2010), Li W (2010), Mori T (2014), Mori T (2014), Mori T (2014), Zhou L (2015), Laulajainen M (2011), Laulajainen M (2011)	14
FBXW5	6	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hu J (2008), He YJ (2006), Kanei-Ishii C (2012)	3
COPS5	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009)	3
CUL4B	8	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Hein MY (2015), Hein MY (2015)	4
COPS5	0	AMBRA1	7	affinity chromatography technology	Bennett EJ (2010)	1
GPS1	1	SAP130	2	affinity chromatography technology, pull down	Menon S (2008), Menon S (2008)	2
UBC	7	DCAF5	1	affinity chromatography technology	Matsumoto M (2005)	1
COPS2	5	DCAF6	0	affinity chromatography technology	Huttlin EL (2015)	1
RFWD2	0	COPS2	5	biochemical, affinity chromatography technology	Yi C (2002), Olma MH (2009)	2
GPS1	1	RBX1	2	affinity chromatography technology	Lyapina S (2001)	1
HDAC1	4	STAT1	1	affinity chromatography technology	Kraemer OH (2006)	1
SIRT7	1	COPS5	0	affinity chromatography technology	Mo Y (2017)	1
ERCC6	6	MDM2	2	affinity chromatography technology, affinity chromatography technology	Latini P (2011), Latini P (2011)	2
RAD21	3	CUL4A	2	affinity chromatography technology	Panigrahi AK (2011)	1
DDA1	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pick E (2007), Olma MH (2009), Olma MH (2009)	3
COPS6	0	DCAF17	0	affinity chromatography technology	Olma MH (2009)	1
SALL2	2	CUL4A	2	pull down	Sung CK (2011)	1
HDAC1	4	ERCC6	6	affinity chromatography technology	Hein MY (2015)	1
COPS6	0	DCAF12	0	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D1	0	COPS7A	0	affinity chromatography technology	Bennett EJ (2010)	1
AHR	3	COPS5	0	affinity chromatography technology, affinity chromatography technology	Lee CC (2016), Lee CC (2016)	2
DDB2	1	DDB1	6	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bergametti F (2002), Martinez E (2001), Guerrero-Santoro J (2008), Angers S (2006), Wang H (2006), Kapetanaki MG (2006), Kapetanaki MG (2006), Higa LA (2006), Takedachi A (2010), Fischer ES (2011), Scrima A (2008), Groisman R (2003), Groisman R (2003), Schroefelbauer B (2007), Kulaksiz G (2005), Inoki T (2004), Bontron S (2002), Rapic-Otrin V (2003), Olma MH (2009), Liu W (2000), Jin J (2006), Huttlin EL (2015), Zhao R (2014), Xie X (2015), Groisman R (2006), Yang Y (2016), Huttlin EL (2017), Chitale S (2017), Fantini D (2017), Fantini D (2017), Ohtake F (2007)	31
DTL	0	MDM2	2	affinity chromatography technology	Banks D (2006)	1
DCLRE1C	3	DDB2	1	affinity chromatography technology, pull down	Yan Y (2011), Yan Y (2011)	2
RASSF1	3	CUL1	7	affinity chromatography technology	Song MS (2008)	1
DNMT3A	17	HDAC1	4	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Fuks F (2001), Fuks F (2001), Fuks F (2001), Hervouet E (2009)	4
NF2	1	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang J (2008), Huang J (2008), Huang J (2008), Li W (2010), Li W (2010), Zhou L (2015)	6
DET1	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Angers S (2006), Jin J (2006), Pick E (2007), Pick E (2007), Pick E (2007), Jin J (2006), Huttlin EL (2017)	8
DDB1	6	RECQL	1	affinity chromatography technology, affinity chromatography technology	Contreras-Levicoy J (2012), Contreras-Levicoy J (2012)	2
SUV39H1	0	HDAC2	1	affinity chromatography technology, pull down	Vaute O (2002), Vaute O (2002)	2
CDKN1A	1	EP300	36	pull down, affinity chromatography technology	Cazzalini O (2008), Cazzalini O (2008)	2
DDB1	6	SUDS3	3	affinity chromatography technology, affinity chromatography technology	Ji Q (2014), Ji Q (2014)	2
DDB1	6	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down	Wang H (2006), Kapetanaki MG (2006), Hu J (2004), Ahn J (2010), Fischer ES (2011), Groisman R (2006)	6
DCAF1	5	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McCall CM (2008), Olma MH (2009), Hein MY (2015)	3
DET1	2	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
RFWD2	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
ARID4B	1	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fleischer TC (2003), Joshi P (2013), Hein MY (2015), Huttlin EL (2017)	4
DDB1	6	DCAF17	0	affinity chromatography technology, affinity chromatography technology	Jin J (2006), Jin J (2006)	2
COPS5	0	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Huang X (2005), Bennett EJ (2010), Kapelari B (2000), Oh W (2006), Olma MH (2009), Havugimana PC (2012), Christmann M (2013), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Scherer PC (2016), Huttlin EL (2017), Boldt K (2016)	15
MDM2	2	SIRT7	1	affinity chromatography technology	Nihira NT (2017)	1
SAP130	2	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fleischer TC (2003), Xue Y (1998), Joshi P (2013), Hein MY (2015), Huttlin EL (2017)	5
CUL4A	2	DCAF15	3	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Jin J (2006)	2
COPS7B	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Boldt K (2016)	2
HIST1H1C	2	CUL4A	2	affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Kim K (2013), Kim K (2013), Kim K (2013), Kim K (2013)	4
DCAF1	5	HIST1H3A	3	pull down, pull down	Kim K (2012), Kim K (2012)	2
BRCA1	7	HDAC1	4	pull down	Yarden RI (1999)	1
DCAF11	2	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
CUL1	7	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Inuzuka H (2010), Inuzuka H (2010), He Y (2014)	3
COPS4	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Huttlin EL (2017)	2
LIG1	4	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Peng Z (2016), Peng Z (2016)	2
ERCC6	6	CUL4B	8	affinity chromatography technology	Latini P (2011)	1
UVRAG	2	RBX1	2	affinity chromatography technology	Yang Y (2016)	1
CUL4A	2	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Min KW (2005), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	10
CUL4A	2	DCAF8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Jin J (2006), Huttlin EL (2017)	5
RFWD2	0	ERCC8	1	affinity chromatography technology	Olma MH (2009)	1
CUL4A	2	PHIP	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010), Olma MH (2009), Jin J (2006)	4
HIST1H1A	0	RBX1	2	affinity chromatography technology	Kim K (2013)	1
COPS6	0	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
CUL1	7	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, enzymatic study, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, pull down, x-ray crystallography, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Dias DC (2002), Kim J (2002), Zheng N (2002), Kim AY (2008), Ohta T (1999), Ohta T (1999), Ohta T (1999), Bloom J (2006), Block K (2005), Hu J (2004), Hwang JW (2003), Furukawa M (2002), Kawakami T (2001), Ohta T (2001), Chen A (2000), Read MA (2000), Wu K (2000), Tan P (1999), Banerjee S (2010), Gao D (2010), Tron AE (2012), Tron AE (2012), Shteingart S (2012), Tan M (2010), Arai T (2003), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), Huang DT (2004), Emberley ED (2012), Gastaldello S (2012), Furukawa M (2000), Furukawa M (2000), Liu J (2002), Liu J (2002), Liu J (2002), Li X (2003), Calabrese MF (2011), Scott DC (2014), Scott DC (2014), Siergiejuk E (2009), Zhou W (2014), Zhou W (2014), Huang DT (2009), Pick E (2007), Morimoto M (2003), Morimoto M (2003), Ohki Y (2009), Duda DM (2008), Duda DM (2008), Wan C (2015), Hao J (2015), Hao J (2015), Han XR (2016), Kuang P (2016), Zhou W (2017), Hu Y (2017), Reitsma JM (2017)	59
MDM2	2	DCAF8	1	affinity chromatography technology	Jacob AG (2014)	1
COPS3	1	DTL	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Higa LA (2006)	2
GRK5	7	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Wu Z (2012), Wu Z (2012)	2
RFWD2	0	CUL1	7	affinity chromatography technology	Olma MH (2009)	1
DCUN1D1	0	COPS4	0	affinity chromatography technology	Bennett EJ (2010)	1
DCAF1	5	COPS8	2	affinity chromatography technology, affinity chromatography technology	Hrecka K (2007), Huttlin EL (2017)	2
CUL4A	2	CDT1	2	affinity chromatography technology, affinity chromatography technology, biochemical	Hu J (2004), Higa LA (2003), He YJ (2006)	3
COPS3	1	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
DDB1	6	RBP1	1	affinity chromatography technology, affinity chromatography technology	Ji Q (2014), Ji Q (2014)	2
BRCA1	7	RICTOR	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Woods NT (2012), Woods NT (2012), Woods NT (2012)	3
COPS3	1	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, two hybrid, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Min KW (2005), Enchev RI (2010), Stotland A (2012), Sharon M (2009), Kapelari B (2000), Tsuge T (2001), Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	12
CUL4B	8	COPS7B	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
CUL4A	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Angers S (2006), Jin J (2006), Wang H (2006), Kapetanaki MG (2006), Matsuda N (2005), Hu J (2004), Hu J (2004), Hu J (2004), Ahn J (2010), Maddika S (2009), Fischer ES (2011), Tan L (2007), He YJ (2006), He YJ (2006), He YJ (2006), McCall CM (2008), McCall CM (2008), Shiyanov P (1999), Bennett EJ (2010), Gastaldello S (2012), Kanei-Ishii C (2012), Hodgson AJ (2012), Kulaksiz G (2005), Wu Z (2012), Wu Z (2012), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Rao F (2014), Wan C (2015), Liu Y (2015), Zha Z (2015), Mouysset J (2015), Gao J (2015), Yang Y (2016), Yang Y (2016), Scherer PC (2016), Eichner R (2016), Mo Y (2017), Mo Y (2017), Peng Z (2016), Higa LA (2006), Ohtake F (2007)	46
COPS7A	0	COPS2	5	affinity chromatography technology, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uhle S (2003), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
RFWD2	0	COPS4	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
SIRT7	1	MTOR	14	affinity chromatography technology	Tsai YC (2012)	1
NEDD8	0	COPS3	1	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
CUL4A	2	DCAF5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010), Jin J (2006)	3
DDB1	6	RBBP4	3	affinity chromatography technology, affinity chromatography technology	He YJ (2006), Mouysset J (2015)	2
CUL1	7	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Min KW (2005), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Reitsma JM (2017)	6
CUL4B	8	DCAF10	2	affinity chromatography technology	Hein MY (2015)	1
CUL4A	2	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009)	7
DDB2	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Olma MH (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
TRPC4AP	4	RBX1	2	affinity chromatography technology	Choi SH (2010)	1
CRBN	2	COPS2	5	affinity chromatography technology	Kroenke J (2014)	1
RFWD2	0	COPS8	2	biochemical, affinity chromatography technology	Yi C (2002), Olma MH (2009)	2
RAD21	3	DDB1	6	affinity chromatography technology, affinity chromatography technology	Panigrahi AK (2011), Panigrahi AK (2011)	2
EP300	36	DDB1	6	affinity chromatography technology, affinity chromatography technology	Datta A (2001), Rapic-Otrin V (2002)	2
COPS8	2	CRBN	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Kroenke J (2014)	2
EP300	36	AHR	3	affinity chromatography technology, two hybrid, biochemical	Tohkin M (2000), Wang J (2011), Ohtake F (2007)	3
DDB1	6	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Jin J (2006), Jin J (2006), Higa LA (2006), Rossi M (2013), Shibata E (2011), Higa LA (2006), Higa LA (2006)	8
RBX1	2	DNMT3A	17	affinity chromatography technology	Yang Y (2015)	1
CUL4B	8	DCUN1D1	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010), Monda JK (2013), Meyer-Schaller N (2009), Kim AY (2008), Kim AY (2008), Monda JK (2013), Keuss MJ (2016)	8
SIRT7	1	HDAC2	1	affinity chromatography technology	Tsai YC (2012)	1
COPS3	1	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	4
DDB1	6	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ji Q (2014), Ji Q (2014), Romani B (2016)	3
NEDD8	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012)	4
FBXW5	6	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hu J (2008), He YJ (2006), Kanei-Ishii C (2012)	3
RFWD2	0	COPS3	1	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
SIRT7	1	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, enzymatic study	Tsai YC (2012), Yoshizawa T (2014), Jiang L (2017), Mo Y (2017), Mo Y (2017), Mo Y (2017), Mo Y (2017)	7
RASSF1	3	KAT2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PYGO2	1	SUPT3H	4	pull down	Chen J (2010)	1
CRBN	2	DDA1	1	affinity chromatography technology	Kroenke J (2014)	1
DCUN1D1	0	GPS1	1	affinity chromatography technology	Bennett EJ (2010)	1
DCAF8	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology	Jin J (2006), Huttlin EL (2017)	2
MUS81	1	DCAF1	5	affinity chromatography technology	Zhou X (2016)	1
HIST1H3A	3	RECQL	1	bioid	Lambert JP (2015)	1
EP300	36	COPS6	0	two hybrid	Stelzl U (2005)	1
DDB1	6	GPS1	1	affinity chromatography technology, pull down, fluorescent resonance energy transfe	Jin J (2006), Emberley ED (2012), Cavadini S (2016)	3
MDM2	2	RECQL	1	affinity chromatography technology	Okoro DR (2013)	1
DDB1	6	TRPC4AP	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Choi SH (2010), Jamal A (2015), Huttlin EL (2017)	4
MCM10	2	CUL4A	2	affinity chromatography technology	Kaur M (2012)	1
CUL4A	2	DCAF4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010), Jin J (2006), Huttlin EL (2017)	4
SIRT7	1	RECQL	1	affinity chromatography technology	Tsai YC (2012)	1
ATXN3	2	CUL1	7	affinity chromatography technology	Tu Y (2017)	1
COPS8	2	COPS7B	0	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	5
CUL1	7	DCAF1	5	affinity chromatography technology	McCall CM (2008)	1
CUL4B	8	DDB2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Higa LA (2006), Bennett EJ (2010), Jin J (2006), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	9
COPS6	0	DCAF4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	4
CUL4B	8	CDT1	2	affinity chromatography technology	Higa LA (2003)	1
GPS1	1	IP6K1	5	pull down	Rao F (2014)	1
ERCC8	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Olma MH (2009)	3
DCAF1	5	UNG	1	pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Ahn J (2010), Ahn J (2010), Ahn J (2011), Wen X (2012), Wen X (2012)	5
RASSF1	3	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Jiang L (2011), Jiang L (2011)	2
CUL1	7	FZR1	1	affinity chromatography technology, affinity chromatography technology	Fukushima H (2013), Fukushima H (2013)	2
DDB1	6	KAT2A	1	affinity chromatography technology, pull down, affinity chromatography technology	Martinez E (2001), Martinez E (2001), Li Y (2011)	3
ERCC6	6	COPS6	0	affinity chromatography technology	Latini P (2011)	1
ERCC8	1	COPS2	5	affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003)	2
SIRT7	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsai YC (2012), Mo Y (2017), Mo Y (2017), Mo Y (2017)	4
EP300	36	HIST1H3A	3	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Liu B (2009), Brackertz M (2006), Faiola F (2005), Daujat S (2002), Kalkhoven E (2002), Seo SB (2002), Kim JH (2005), Bordoli L (2001), Kim MY (2001), Kutney SN (2004), Wang F (2010), Loven MA (2004), Kiernan RE (1999), Wong K (2005), Ogryzko VV (1996), Yamaguchi Y (2004), Furumatsu T (2005), An W (2002), Delvecchio M (2013), Delvecchio M (2013), Tropberger P (2013), Das C (2009), Shimura M (2011), Ji A (2003), Fu M (2005), Suganuma T (2002), Tang Z (2013), Kim JH (2006), Lopes da Rosa J (2013), Li X (2014), Wang YL (2008), Du C (2017), Yi P (2017), Wan W (2017)	34
ATXN3	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Tu Y (2017), Tu Y (2017)	2
SAP30	1	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang NE (2003), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Zhang Y (1999), Zhang Y (1999), Swanson KA (2004), Yochum GS (2001), Kuzmichev A (2002), Kuzmichev A (2002), Viiri KM (2006), Binda O (2008), Lai A (2001), Skowyra D (2001), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Xue Y (1998), Bantscheff M (2011), Joshi P (2013), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	24
COPS8	2	DCAF11	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Boldt K (2016)	2
DCUN1D1	0	COPS5	0	affinity chromatography technology	Bennett EJ (2010)	1
DCAF4	3	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Hein MY (2015), Huttlin EL (2017)	3
DDB2	1	HIST1H3A	3	affinity chromatography technology, affinity chromatography technology	Fantini D (2017), Fantini D (2017)	2
CUL4A	2	DCAF6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Angers S (2006), Bennett EJ (2010), Olma MH (2009), Jin J (2006), Chen HH (2017)	5
COPS6	0	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Olma MH (2009)	5
DCAF4L2	3	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017), Wang H (2016)	3
DDA1	1	DCAF16	0	affinity chromatography technology	Olma MH (2009)	1
COPS6	0	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Enchev RI (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
TRPC4AP	4	CUL4B	8	affinity chromatography technology	Huttlin EL (2017)	1
DDB1	6	COPS8	2	affinity chromatography technology, pull down	Angers S (2006), Emberley ED (2012)	2
MCM10	2	CDKN1A	1	pull down	Ramachandran N (2004)	1
GRK5	7	CUL4B	8	affinity chromatography technology, affinity chromatography technology	Wu Z (2012), Wu Z (2012)	2
RAD21	3	UBC	7	affinity chromatography technology	Panigrahi AK (2011)	1
CDKN1A	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Abbas T (2008), Abbas T (2008), Gao J (2015)	3
PYGO2	1	CUL4A	2	affinity chromatography technology	Li Q (2015)	1
FZR1	1	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PYGO2	1	DDB1	6	pull down, affinity chromatography technology, affinity chromatography technology	Li Q (2015), Li Q (2015), Li Q (2015)	3
CUL1	7	CDKN1A	1	affinity chromatography technology	Yu ZK (1998)	1
BRCA1	7	CRBN	2	affinity chromatography technology	Ertych N (2016)	1
DDB1	6	COPS4	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Angers S (2006), Jin J (2006), Emberley ED (2012), Olma MH (2009)	4
CUL1	7	DDB1	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Gastaldello S (2012)	2
RORA	4	DDB1	6	affinity chromatography technology, affinity chromatography technology	Lee JM (2012), Lee JM (2012)	2
ATXN3	2	EP300	36	pull down, affinity chromatography technology	Li F (2002), Li F (2002)	2
SIRT7	1	DCAF1	5	affinity chromatography technology	Yoshizawa T (2014)	1
COPS5	0	TRPC4AP	4	affinity chromatography technology	Bennett EJ (2010)	1
COPS3	1	CRBN	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Kroenke J (2014)	2
COPS6	0	DCAF10	2	affinity chromatography technology	Olma MH (2009)	1
COPS5	0	CRBN	2	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Kroenke J (2014)	2
DCLRE1C	3	BRCA1	7	affinity chromatography technology	Zhang X (2004)	1
HUWE1	22	HDAC2	1	affinity chromatography technology, enzymatic study	Zhang J (2011), Zhang J (2011)	2
RASSF1	3	FZR1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL4A	2	UBC	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Angers S (2006), Bennett EJ (2010), Olma MH (2009), Wu K (2016)	4
COPS3	1	DCAF4	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL1	7	CHEK1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu S (2009), Huh J (2013), Zhang YW (2005)	3
HDAC1	4	TP73	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Uramoto H (2004), Uramoto H (2004), Uramoto H (2004), Zhang J (2007)	4
AMBRA1	7	COPS8	2	affinity chromatography technology	Antonioli M (2014)	1
DDB1	6	DNMT3A	17	affinity chromatography technology, pull down	Yang Y (2015), Yang Y (2015)	2
COPS8	2	COPS5	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Olma MH (2009), Asare Y (2013), Huttlin EL (2015), Huttlin EL (2017), Boldt K (2016)	9
DCLRE1C	3	DDB1	6	pull down, affinity chromatography technology	Yan Y (2011), Yan Y (2011)	2
ERCC8	1	EP300	36	affinity chromatography technology	Fousteri M (2006)	1
ERCC6	6	COPS4	0	affinity chromatography technology	Latini P (2011)	1
CUL4B	8	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Hein MY (2015), Yang Y (2015)	4
COPS5	0	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
GPS1	1	COPS7A	0	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Wan C (2015), Hein MY (2015), Huang X (2016)	6
DDB1	6	COPS5	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Angers S (2006), Jin J (2006), Emberley ED (2012), Bennett EJ (2010), Olma MH (2009), He F (2013)	6
DET1	2	COPS7B	0	affinity chromatography technology	Huttlin EL (2017)	1
DDB2	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Olma MH (2009), Olma MH (2009), Hein MY (2015)	6
ARID4B	1	SAP130	2	affinity chromatography technology, biochemical	Fleischer TC (2003), Wan C (2015)	2
DDB1	6	CRBN	2	affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology	Angers S (2006), Ito T (2010), Chamberlain PP (2014), Liu Y (2015), Diaz-Rodriguez E (2016), Xu Q (2016), Xu G (2013), Nguyen TV (2016), Nguyen TV (2016), Eichner R (2016), Matyskiela ME (2018), Kroenke J (2014)	12
AMBRA1	7	UBC	7	affinity chromatography technology	Antonioli M (2014)	1
DDB1	6	SUV39H1	0	affinity chromatography technology, pull down	Yang Y (2015), Yang Y (2015)	2
LRWD1	1	DDB1	6	affinity chromatography technology, affinity chromatography technology	Shen Z (2012), Shen Z (2012)	2
CUL4B	8	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Olma MH (2009)	2
KAT2A	1	DTL	0	affinity chromatography technology, enzymatic study	Li Y (2011), Li Y (2011)	2
CUL4B	8	UBC	7	affinity chromatography technology, pull down	Bennett EJ (2010), Nathan JA (2013)	2
AHR	3	NEDD8	0	pull down, affinity chromatography technology	Antenos M (2002), Antenos M (2002)	2
CUL4A	2	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2017)	6
DTL	0	CDT1	2	enzymatic study, pull down, pull down	Hayashi A (2014), Chandrasekaran S (2011), Coleman KE (2015)	3
DDB1	6	ARID4B	1	affinity chromatography technology, affinity chromatography technology	Ji Q (2014), Ji Q (2014)	2
AMBRA1	7	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Jin J (2006), Antonioli M (2014), Antonioli M (2014), Antonioli M (2014)	4
DCAF4L2	3	COPS5	0	affinity chromatography technology	Wang H (2016)	1
MTOR	14	AMBRA1	7	enzymatic study	Nazio F (2013)	1
PYGO2	1	DCAF1	5	pull down	Li Q (2015)	1
CDKN1A	1	ATXN3	2	two hybrid	Vinayagam A (2011)	1
COPS5	0	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Fang L (2008), Enchev RI (2010), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Olma MH (2009), Asare Y (2013), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	13
COPS6	0	COPS7A	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sharon M (2009), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	15
CHEK1	2	CDKN1A	1	affinity chromatography technology	Tian H (2002)	1
DNMT3A	17	HIST1H3A	3	pull down, bioid, unspecified method, pull down	Otani J (2009), Lambert JP (2015), Sankaran SM (2016), Sankaran SM (2016)	4
CUL4B	8	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Higa LA (2006)	5
DCAF4L2	3	COPS7B	0	affinity chromatography technology	Wang H (2016)	1
DDB2	1	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Hein MY (2015)	4
HDAC1	4	MDM2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Ito A (2002), Ito A (2002), Ito A (2002), Gaughan L (2005), Gaughan L (2005)	5
MDM2	2	TP73	2	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Balint E (1999), Zeng X (1999), Zeng X (1999), Chen L (2010), Zdzalik M (2010), Kim JW (2008), Balint E (1999), Balint E (1999), Wang J (2011), Ongkeko WM (1999), Ongkeko WM (1999), Ongkeko WM (1999), Ongkeko WM (1999), Wu H (2015), Stindt MH (2015), Zhou X (2015), Zhou X (2015)	17
COPS6	0	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), McCall CM (2008), Bennett EJ (2010), Olma MH (2009)	4
NEDD8	0	DCAF11	2	affinity chromatography technology	Bennett EJ (2010)	1
RFWD2	0	COPS6	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Olma MH (2009), Olma MH (2009), Choi HH (2011), Choi HH (2011)	4
DCUN1D1	0	UBC	7	affinity chromatography technology, pull down, affinity chromatography technology	Bennett EJ (2010), Huang G (2014), Huang G (2014)	3
DCAF4L2	3	COPS8	2	affinity chromatography technology	Wang H (2016)	1
EP300	36	CDT1	2	enzymatic study	Glozak MA (2009)	1
DDA1	1	ERCC8	1	affinity chromatography technology	Olma MH (2009)	1
COPS5	0	DCAF4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2017)	3
HIST1H1A	0	RBBP4	3	pull down	Martin C (2006)	1
CUL4B	8	SUV39H1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015)	5
COPS8	2	COPS6	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	10
CUL1	7	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Min KW (2005), Min KW (2005), Yang X (2002), Yang X (2002), Huang X (2005), Bennett EJ (2010), Scherer PC (2016), Scherer PC (2016), Reitsma JM (2017)	9
RPTOR	4	CUL4A	2	affinity chromatography technology	Hussain S (2013)	1
HIST1H1A	0	DCAF1	5	affinity chromatography technology, affinity chromatography technology	Kim K (2013), Kim K (2013)	2
DCUN1D1	0	DDB1	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Keuss MJ (2016)	2
GPS1	1	COPS7B	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Stotland A (2012), Havugimana PC (2012), Huang X (2016), Huttlin EL (2017)	4
DDB1	6	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Jin J (2006), Groisman R (2003), Groisman R (2003), Meulenbroek EM (2012), Fei J (2012), Jin J (2006), He J (2016), Groisman R (2006), Chitale S (2017), Ohtake F (2007)	10
RBP1	1	SAP30	1	affinity chromatography technology	Binda O (2006)	1
DCUN1D1	0	NEDD8	0	affinity chromatography technology	Bennett EJ (2010)	1
RFWD2	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Higa LA (2006), He YJ (2006), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Lu G (2014)	7
SIN3A	13	ARID4B	1	affinity chromatography technology, affinity chromatography technology, biochemical	Fleischer TC (2003), Fleischer TC (2003), Wan C (2015)	3
SALL2	2	CUL4B	8	pull down	Sung CK (2011)	1
EP300	36	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Paulson M (1999), Hiroi M (2003), Ray S (2002), Strassheim D (2009), Liu X (2008), Ghosh AK (2001), Yang WS (2005), Zhang Y (2015), Kotla S (2015), Kotla S (2015)	10
COPS4	0	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
AMBRA1	7	DDA1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Behrends C (2010), Olma MH (2009), Antonioli M (2014)	4
RBX1	2	RICTOR	4	affinity chromatography technology, affinity chromatography technology	Gao D (2010), Gao D (2010)	2
ERCC8	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003)	2
COPS5	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Neuss H (2007), Fang L (2008), Orel L (2010), Uhle S (2003), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	17
HDAC1	4	DCAF1	5	pull down, affinity chromatography technology, affinity chromatography technology	Kim K (2012), Romani B (2016), Romani B (2016)	3
DTL	0	RBX1	2	affinity chromatography technology	Shibata E (2011)	1
DDB1	6	DCAF6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Jin J (2006), Chen HH (2017), Chen HH (2017), Chen HH (2017)	6
DCAF1	5	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McCall CM (2008), Hrecka K (2007), Olma MH (2009)	3
CDKN1A	1	COPS6	0	two hybrid	Vinayagam A (2011)	1
CRBN	2	SUV39H1	0	two hybrid	Weimann M (2013)	1
ATXN3	2	NEDD8	0	two hybrid, two hybrid, pull down	Ferro A (2007), Ferro A (2007), Ferro A (2007)	3
DDA1	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Hein MY (2015)	2
CUL4A	2	DCAF10	2	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010)	2
DCAF6	0	CUL4B	8	affinity chromatography technology	Jin J (2006)	1
RBX1	2	NEDD8	0	affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Norman JA (2006)	2
DDB1	6	UBA1	1	affinity chromatography technology, affinity chromatography technology	Panigrahi AK (2011), Panigrahi AK (2011)	2
COPS6	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	12
DCAF4L2	3	COPS3	1	affinity chromatography technology	Wang H (2016)	1
DDB1	6	10607	0	affinity chromatography technology, affinity chromatography technology	Ohtake F (2007), Ohtake F (2007)	2
COPS6	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	5
COPS6	0	GPS1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Stotland A (2012), Sharon M (2009), Bennett EJ (2010), Lingaraju GM (2014), Huttlin EL (2015), Huttlin EL (2017)	7
COPS6	0	UBC	7	affinity chromatography technology	Bennett EJ (2010)	1
COPS8	2	DTL	0	affinity chromatography technology	Huttlin EL (2017)	1
CUL4B	8	SUDS3	3	affinity chromatography technology, affinity chromatography technology, biochemical	Ji Q (2014), Ji Q (2014), Ji Q (2014)	3
CRBN	2	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ito T (2010), Xu G (2013), Nguyen TV (2016), Nguyen TV (2016), Kroenke J (2014)	5
CHEK1	2	DTL	0	affinity chromatography technology, enzymatic study, enzymatic study	Huh J (2013), Cheng YC (2013), Huh J (2013)	3
DDA1	1	DTL	0	affinity chromatography technology	Olma MH (2009)	1
MTOR	14	RICTOR	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jacinto E (2004), Jacinto E (2004), Sarbassov DD (2004), Sarbassov DD (2004), Sarbassov DD (2004), Frias MA (2006), Jacinto E (2006), Yang Q (2006), Frias MA (2006), Sarbassov DD (2006), Sarbassov DD (2005), Yang Q (2006), Kaizuka T (2010), Pearce LR (2007), Oh WJ (2010), Oh WJ (2010), Agrawal P (2012), Guo Z (2012), Sarbassov DD (2006), Sancak Y (2007), Yang Q (2006), Jacinto E (2006), Jacinto E (2006), Rosner M (2010), Ikenoue T (2008), Ikenoue T (2008), Murata H (2011), Murata H (2011), Koike-Kumagai M (2009), Koike-Kumagai M (2009), Woods NT (2012), Hussain S (2013), Peterson TR (2009), Peterson TR (2009), Su WC (2009), Hernandez-Negrete I (2007), Ramirez-Rangel I (2011), Martin J (2008), Martin J (2008), Martin J (2008), Thedieck K (2007), Thedieck K (2007), Thedieck K (2007), McDonald PC (2008), McDonald PC (2008), Hong F (2008), Hong F (2008), Facchinetti V (2008), Toschi A (2009), Zhang F (2010), Chen CH (2011), Chen CH (2011), Xu Y (2013), Xu Y (2013), Glidden EJ (2012), Glidden EJ (2012), Vander Haar E (2007), Koo J (2015), Thedieck K (2007)	59
ERCC6	6	COPS3	1	affinity chromatography technology	Latini P (2011)	1
TRPC4AP	4	DDA1	1	affinity chromatography technology, affinity chromatography technology	Choi SH (2010), Huttlin EL (2017)	2
UBC	7	UCHL1	1	two hybrid, enzymatic study, enzymatic study, x-ray crystallography, pull down, pull down, enzymatic study, pull down, enzymatic study, pull down, enzymatic study, pull down, pull down	Stelzl U (2005), Bremm A (2010), Boudreaux D (2012), Boudreaux DA (2010), Boudreaux DA (2010), Phillips AH (2013), Larsen CN (1998), Duerksen-Hughes PJ (1989), Flierman D (2016), Kwasna D (2018), Lee YC (2017), Lee YC (2017), Hanpude P (2017)	13
COPS7B	0	COPS7A	0	biochemical, affinity chromatography technology	Kristensen AR (2012), Huttlin EL (2017)	2
DDA1	1	COPS4	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
TP73	2	EP300	36	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Strano S (2005), Uramoto H (2004), Zeng X (2000), Zeng X (2000), Zeng X (2000), Zeng X (2000), Zeng X (2000), Mantovani F (2004), Burge S (2009), Burge S (2009), Costanzo A (2002), Hoffmann A (2008), Kramer D (2015)	13
DDA1	1	DDB2	1	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Hein MY (2015)	2
SUV39H1	0	RBBP4	3	pull down	Vaute O (2002)	1
HIST1H1C	2	DCAF1	5	affinity chromatography technology, affinity chromatography technology	Kim K (2013), Kim K (2013)	2
CUL4B	8	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Fei J (2012), Hein MY (2015)	3
COPS5	0	COPS6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Fang L (2008), Sharon M (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Choi HH (2011), Kristensen AR (2012), Birol M (2014), Birol M (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	18
COPS5	0	DCAF8	1	affinity chromatography technology	Bennett EJ (2010)	1
BRCA1	7	HUWE1	22	affinity chromatography technology, affinity chromatography technology	Wang X (2014), Wang X (2014)	2
HIST1H1A	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Kim K (2013), Kim K (2013)	2
DCAF4	3	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
DDB1	6	DCAF15	3	affinity chromatography technology, affinity chromatography technology	Jin J (2006), Jin J (2006)	2
CUL4A	2	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), He YJ (2006), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006), Huttlin EL (2017), Lo JY (2017)	10
RBX1	2	SUV39H1	0	affinity chromatography technology	Yang Y (2015)	1
NEDD8	0	UCHL1	1	two hybrid	Stelzl U (2005)	1
GPS1	1	NF2	1	affinity chromatography technology	Stotland A (2012)	1
DDB1	6	SALL2	2	affinity chromatography technology, affinity chromatography technology, pull down	Sung CK (2011), Sung CK (2011), Sung CK (2011)	3
COPS2	5	SIN3A	13	affinity chromatography technology, pull down, pull down, two hybrid	Dressel U (1999), Moehren U (2004), Moehren U (2004), Moehren U (2004)	4
CHEK1	2	MTOR	14	genetic interference, genetic interference, genetic interference	Shen JP (2017), Srivas R (2016), Srivas R (2016)	3
COPS2	5	HIST1H3A	3	pull down	Eckey M (2007)	1
RFWD2	0	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Jin J (2006), He YJ (2006), Olma MH (2009), Lu G (2014), Lu G (2014)	6
MCM10	2	RBX1	2	affinity chromatography technology	Kaur M (2012)	1
DCAF4	3	COPS4	0	affinity chromatography technology	Huttlin EL (2017)	1
UBC	7	BRCA1	7	pull down, enzymatic study	Sobhian B (2007), Zhao GY (2007)	2
CUL4A	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guerrero-Santoro J (2008), Angers S (2006), Bennett EJ (2010), Bennett EJ (2010), Sertic S (2013)	5
DYRK2	1	DCAF1	5	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Maddika S (2009), Maddika S (2009), Maddika S (2009), Maddika S (2009), Hossain D (2017)	5
DCAF1	5	COPS7B	0	affinity chromatography technology	McCall CM (2008)	1
SIRT7	1	RBBP4	3	affinity chromatography technology	Tsai YC (2012)	1
UVRAG	2	DDB2	1	affinity chromatography technology	Yang Y (2016)	1
SUDS3	3	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fleischer TC (2003), Alland L (2002), Joshi P (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
RFWD2	0	COPS5	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
DDB2	1	ERCC8	1	affinity chromatography technology	Groisman R (2003)	1
DCAF8	1	DDB1	6	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Olma MH (2009), Klein CJ (2014), Jin J (2006), Huttlin EL (2017)	6
COPS4	0	COPS7A	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, biochemical, pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Sharon M (2009), Luke-Glaser S (2007), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huang X (2016)	13
ERCC6	6	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study	Anindya R (2010), Fousteri M (2006), Henning KA (1995), Latini P (2011), Latini P (2011), Fei J (2012), He J (2016), Groisman R (2006), Groisman R (2006), Groisman R (2006)	10
CRBN	2	GPS1	1	affinity chromatography technology	Kroenke J (2014)	1
GPS1	1	COPS4	0	affinity chromatography technology, two hybrid, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical	Stotland A (2012), Tsuge T (2001), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Wan C (2015)	7
BRCA1	7	MTOR	14	affinity chromatography technology	Woods NT (2012)	1
COPS6	0	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	9
DCAF4L2	3	COPS4	0	affinity chromatography technology	Wang H (2016)	1
SAP130	2	CUL1	7	affinity chromatography technology	Menon S (2008)	1
CHEK1	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Leung-Pineda V (2009), Leung-Pineda V (2009), Huh J (2013), Williamson EA (2014)	4
SUDS3	3	HDAC2	1	affinity chromatography technology, affinity chromatography technology	Fleischer TC (2003), Joshi P (2013)	2
COPS7A	0	DCAF10	2	affinity chromatography technology	Hein MY (2015)	1
NEDD8	0	DCAF1	5	affinity chromatography technology	Bennett EJ (2010)	1
STAT1	1	MTOR	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique	Kristof AS (2003), Kristof AS (2003), Fielhaber JA (2009), Fielhaber JA (2009), Fielhaber JA (2009), Chen TC (2014)	6
DDA1	1	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Behrends C (2010), Hrecka K (2007), Hrecka K (2007), Olma MH (2009), Olma MH (2009), Wan C (2015)	6
KAT2A	1	CUL4A	2	affinity chromatography technology	Li Y (2011)	1
CUL4B	8	SAP30	1	affinity chromatography technology, affinity chromatography technology	Ji Q (2014), Ji Q (2014)	2
DET1	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Angers S (2006), Jin J (2006), Pick E (2007), Huttlin EL (2017)	5
ATXN3	2	UBC	7	pull down, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, pull down, x-ray crystallography, affinity chromatography technology, pull down, enzymatic study, pull down, enzymatic study, pull down, enzymatic study, enzymatic study, x-ray crystallography, pull down, imaging technique, enzymatic study, pull down	Winborn BJ (2008), Mao Y (2005), Berke SJ (2005), Matsumoto M (2005), Bremm A (2010), Nicastro G (2010), Nicastro G (2010), Donaldson KM (2003), Chai Y (2004), Chai Y (2004), Nathan JA (2013), Seki T (2013), Yang H (2014), Yang H (2014), Blount JR (2014), Evers MM (2013), Weeks SD (2011), Donaldson KM (2003), Winborn BJ (2008), Faggiano S (2015), Wauer T (2015), Satoh T (2014), Satoh T (2014), Zhang X (2017), Toonen LJA (2017), Toonen LJA (2017), Kwasna D (2018)	27
DET1	2	COPS2	5	affinity chromatography technology	Huttlin EL (2017)	1
CUL4A	2	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Hein MY (2015)	7
SUV39H1	0	HDAC1	4	affinity chromatography technology, pull down	Vaute O (2002), Vaute O (2002)	2
MDM2	2	UCHL1	1	affinity chromatography technology	Li L (2010)	1
DCAF17	0	CUL4A	2	affinity chromatography technology	Jin J (2006)	1
DDA1	1	DCAF6	0	affinity chromatography technology	Olma MH (2009)	1
CUL4B	8	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Hein MY (2015), Higa LA (2006)	3
CUL1	7	RICTOR	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Gao D (2010), Gao D (2010), Gao D (2010), Gao D (2010)	4
SIN3A	13	RBBP4	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hassig CA (1997), Zhang Y (1998), Nakamura T (2002), Pflum MK (2001), Pflum MK (2001), Skowyra D (2001), Bantscheff M (2011), Hauri S (2016)	8
CHEK1	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Leung-Pineda V (2009), Liu S (2009), Huh J (2013), Zhang YW (2005)	4
DDA1	1	DCAF12	0	affinity chromatography technology	Olma MH (2009)	1
NEDD8	0	GPS1	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL4A	2	CUL1	7	biochemical	He YJ (2006)	1
CDKN1A	1	RBBP4	3	two hybrid	Vinayagam A (2011)	1
RPTOR	4	UCHL1	1	affinity chromatography technology	Hussain S (2013)	1
BRCA1	7	TP73	2	affinity chromatography technology	Ibrahim N (2010)	1
DDB2	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	7
UBC	7	HUWE1	22	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study	Nathan JA (2013), Bish RA (2007), Thompson JW (2014), Kristariyanto YA (2015), Zhang X (2017), Michel MA (2017)	6
MDM2	2	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Wang L (2011), Wang L (2011)	2
DCAF4L2	3	COPS6	0	affinity chromatography technology	Wang H (2016)	1
RASSF1	3	SUV39H1	0	affinity chromatography technology, two hybrid	Weimann M (2013), Weimann M (2013)	2
CUL4B	8	SAP130	2	affinity chromatography technology, affinity chromatography technology, biochemical	Ji Q (2014), Ji Q (2014), Ji Q (2014)	3
DDB1	6	SIN3A	13	affinity chromatography technology, affinity chromatography technology, pull down	Ji Q (2014), Ji Q (2014), Ji Q (2014)	3
DDB1	6	DCAF4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Jin J (2006), Huttlin EL (2017)	4
DET1	2	COPS7A	0	affinity chromatography technology	Huttlin EL (2017)	1
RFWD2	0	DCAF1	5	affinity chromatography technology	Olma MH (2009)	1
CUL4B	8	ARID4B	1	affinity chromatography technology, affinity chromatography technology	Ji Q (2014), Ji Q (2014)	2
TP73	2	CDT1	2	affinity chromatography technology	Lunardi A (2010)	1
RAG1	1	CUL4A	2	affinity chromatography technology	Kassmeier MD (2011)	1
DDB1	6	STAT1	1	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
COPS5	0	DDB2	1	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), He YJ (2006), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Kulaksiz G (2005), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
CUL4B	8	RBP1	1	affinity chromatography technology, affinity chromatography technology	Ji Q (2014), Ji Q (2014)	2
SIRT7	1	RAD21	3	affinity chromatography technology	Tsai YC (2012)	1
DCAF1	5	HDAC2	1	affinity chromatography technology, affinity chromatography technology	Romani B (2016), Romani B (2016)	2
NEDD8	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010)	3
DCAF8	1	SUV39H1	0	affinity chromatography technology, two hybrid	Weimann M (2013), Weimann M (2013)	2
UBC	7	RBBP4	3	affinity chromatography technology	Matsumoto M (2005)	1
DDA1	1	COPS8	2	affinity chromatography technology	Olma MH (2009)	1
AHR	3	10607	0	affinity chromatography technology, pull down, pull down	Ohtake F (2007), Ohtake F (2007), Ohtake F (2007)	3
AMBRA1	7	GPS1	1	affinity chromatography technology	Antonioli M (2014)	1
DET1	2	DDA1	1	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pick E (2007), Pick E (2007), Pick E (2007), Olma MH (2009), Pick E (2007), Huttlin EL (2017)	6
HUWE1	22	DDB1	6	affinity chromatography technology, affinity chromatography technology	Thompson JW (2014), Yi J (2015)	2
DDB1	6	SAP130	2	affinity chromatography technology, affinity chromatography technology	Ji Q (2014), Ji Q (2014)	2
BRCA1	7	RPTOR	4	affinity chromatography technology	Ertych N (2016)	1
COPS5	0	CHEK1	2	affinity chromatography technology	Bennett EJ (2010)	1
COPS7A	0	DTL	0	affinity chromatography technology	Hein MY (2015)	1
LRWD1	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Shen Z (2012), Shen Z (2012)	2
HUWE1	22	MDM2	2	affinity chromatography technology, enzymatic study	Kurokawa M (2013), Kurokawa M (2013)	2
GPS1	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Stotland A (2012), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Scherer PC (2016)	5
DDB2	1	COPS8	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
DDB2	1	COPS7B	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HUWE1	22	CUL4B	8	affinity chromatography technology, affinity chromatography technology, enzymatic study	Yi J (2015), Yi J (2015), Yi J (2015)	3
CUL4A	2	RBBP4	3	affinity chromatography technology	He YJ (2006)	1
DET1	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology	Jin J (2006), Huttlin EL (2017)	2
SAP130	2	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fleischer TC (2003), Xue Y (1998), Joshi P (2013)	3
CDKN1A	1	DTL	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Abbas T (2008), Abbas T (2008), Nishitani H (2008), Kim DH (2010), Zhang L (2012), Abbas T (2008), Shibata E (2011)	7
ERCC6	6	BRCA1	7	affinity chromatography technology, enzymatic study	Wei L (2011), Wei L (2011)	2
GRK5	7	SIN3A	13	affinity chromatography technology	Wu Z (2012)	1
DCAF1	5	COPS4	0	affinity chromatography technology, affinity chromatography technology	McCall CM (2008), Olma MH (2009)	2
SAP30	1	HDAC2	1	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (1998), Zhang Y (1999), Kuzmichev A (2002), Viiri KM (2006), Lai A (2001), Zhang Y (1998), Zhang Y (1998), Adenuga D (2010), Xue Y (1998), Bantscheff M (2011), Hein MY (2015)	11
MTOR	14	EP300	36	enzymatic study	Wan W (2017)	1
DDB1	6	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Norman JA (2006), Bennett EJ (2010)	3
RBBP4	3	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Yao YL (2003), Nicolas E (2001), Nicolas E (2001), Grozinger CM (1999), You A (2001), Hassig CA (1997), Hassig CA (1997), Ng HH (1999), Zhang Y (1999), Zhang Y (2002), Hassig CA (1998), Zhang Y (1997), Banach-Orlowska M (2009), Pflum MK (2001), Pflum MK (2001), Skowyra D (2001), Humphrey GW (2001), Zhang Y (1998), Zhang Y (1998), Sun JM (2007), Sun JM (2007), Karwowska-Desaulniers P (2007), Terhune SS (2010), Xue Y (1998), Xue Y (1998), Cui S (2011), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Hauri S (2016)	35
SIN3A	13	SUDS3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fleischer TC (2003), Fleischer TC (2003), Fleischer TC (2003), Alland L (2002), Alland L (2002), Alland L (2002), Huttlin EL (2015), Huttlin EL (2017)	8
RBBP4	3	BRCA1	7	pull down, affinity chromatography technology, affinity chromatography technology	Yarden RI (1999), Yarden RI (1999), Ertych N (2016)	3
NR1I2	5	DDB1	6	affinity chromatography technology, affinity chromatography technology	Ong SS (2014), Ong SS (2014)	2
DDA1	1	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Lu G (2014)	2
DDB1	6	AMBRA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Behrends C (2010), Jin J (2006), Antonioli M (2014), Antonioli M (2014)	5
COPS5	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), He F (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
DET1	2	COPS4	0	affinity chromatography technology	Huttlin EL (2017)	1
COPS6	0	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huang X (2005), Bennett EJ (2010), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	11
CUL4B	8	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
CDKN1A	1	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Abbas T (2008), Abbas T (2008), Nishitani H (2008), Fogeron ML (2013)	4
CEP78	2	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Hossain D (2017), Hossain D (2017), Hossain D (2017), Hossain D (2017)	4
COPS3	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
FZR1	1	KAT2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ERCC8	1	COPS8	2	affinity chromatography technology, affinity chromatography technology, biochemical	Groisman R (2003), Groisman R (2003), Groisman R (2006)	3
DDA1	1	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
RAG1	1	DDB1	6	biochemical, affinity chromatography technology	Kassmeier MD (2011), Kassmeier MD (2011)	2
NEDD8	0	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL4A	2	DCAF12	0	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010)	2
RPTOR	4	RICTOR	4	affinity chromatography technology, affinity chromatography technology	Rosner M (2010), Rosner M (2010)	2
COPS5	0	DDA1	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
RASSF1	3	DDB1	6	affinity chromatography technology, affinity chromatography technology, pull down	Jiang L (2011), Jiang L (2011), Jiang L (2011)	3
SIRT7	1	HIST1H3A	3	pull down	Ford E (2006)	1
COPS6	0	DDA1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Olma MH (2009)	4
CDT1	2	DDB2	1	affinity chromatography technology	Hu J (2004)	1
INO80	5	DDB1	6	affinity chromatography technology, affinity chromatography technology	Jiang Y (2010), Jiang Y (2010)	2
GRK5	7	RBX1	2	affinity chromatography technology	Wu Z (2012)	1
DCAF4L2	3	HIST1H1C	2	affinity chromatography technology	Wang H (2016)	1
DCAF17	0	CUL4B	8	affinity chromatography technology	Jin J (2006)	1
RBX1	2	CUL4A	2	affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, biochemical, enzymatic study, pull down, biochemical	Dias DC (2002), Ohta T (1999), Guerrero-Santoro J (2008), Hu J (2004), Furukawa M (2002), Maddika S (2009), Tron AE (2012), Tron AE (2012), He YJ (2006), Gastaldello S (2012), Olma MH (2009), Kristensen AR (2012), Huang DT (2009), Pick E (2007), Yang Y (2016), Scherer PC (2016), Nguyen TV (2016)	17
PYGO2	1	NF2	1	pull down	Chen J (2010)	1
DDB2	1	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	6
ERCC8	1	RBX1	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Groisman R (2003), Groisman R (2003), Groisman R (2006), Groisman R (2006)	4
DCAF1	5	UBC	7	affinity chromatography technology	Li W (2010)	1
RORA	4	COPS5	0	two hybrid	Albers M (2005)	1
KAT2A	1	HIST1H3A	3	enzymatic study, enzymatic study, enzymatic study, enzymatic study	Faiola F (2005), Yamaguchi Y (2004), Guelman S (2009), Wang YL (2008)	4
GRK5	7	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wu Z (2012), Wu Z (2012), Wu Z (2012)	3
DCAF8	1	COPS4	0	biochemical	Kristensen AR (2012)	1
DCUN1D1	0	RBX1	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Kim AY (2008), Kim AY (2008), Bommelje CC (2013), Meyer-Schaller N (2009), Huang G (2014), Huang G (2014), Keuss MJ (2016), Keuss MJ (2016)	9
SIN3A	13	SAP130	2	affinity chromatography technology, affinity chromatography technology, biochemical	Fleischer TC (2003), Fleischer TC (2003), Wan C (2015)	3
DDA1	1	WDTC1	1	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Olma MH (2009)	2
SIRT7	1	COPS4	0	affinity chromatography technology	Mo Y (2017)	1
UBC	7	RECQL	1	pull down	Zhang X (2017)	1
COPS5	0	SAP130	2	affinity chromatography technology	Menon S (2008)	1
CUL4A	2	BRWD1	6	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010)	2
HIST1H3A	3	RBBP4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method	Wysocka J (2006), Nishioka K (2002), Tagami H (2004), Foltz DR (2009), Millard CJ (2016)	5
DCAF11	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Hein MY (2015), Huttlin EL (2017)	3
HIST1H3A	3	HDAC1	4	affinity chromatography technology, pull down, affinity chromatography technology	Nishioka K (2002), Li X (2014), Hein MY (2015)	3
DDB1	6	DCAF1	5	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Jin J (2006), Jin J (2006), Ahn J (2010), Maddika S (2009), Maddika S (2009), McCall CM (2008), McCall CM (2008), Hrecka K (2007), Hrecka K (2007), Le Rouzic E (2007), Le Rouzic E (2007), Olma MH (2009), Pham TN (2011), Gerard FC (2014), Nakagawa T (2015), Wan C (2015), Kyei GB (2015), Cassiday PA (2015), Gao J (2015), Gao J (2015), Wu Y (2016), Wu Y (2016), Wang H (2017), Zhou X (2016), Zhou X (2016), Wang X (2017)	26
HIST1H3A	3	HIST1H1C	2	imaging technique	Soldi M (2013)	1
CUL4A	2	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Angers S (2006), Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009)	7
DET1	2	RBX1	2	affinity chromatography technology	Wertz IE (2004)	1
COPS5	0	UBC	7	affinity chromatography technology	Bennett EJ (2010)	1
COPS6	0	DCAF16	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
SIRT7	1	DCAF5	1	affinity chromatography technology	Mo Y (2017)	1
COPS5	0	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sowa ME (2009), Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Birol M (2014)	5
CUL1	7	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huang X (2016), Reitsma JM (2017)	3
NR1I2	5	DYRK2	1	affinity chromatography technology, enzymatic study	Ong SS (2014), Ong SS (2014)	2
EP300	36	MDM2	2	pull down, affinity chromatography technology, biochemical, pull down, pull down, enzymatic study, affinity chromatography technology, biochemical, enzymatic study	Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Matt T (2004), Wang X (2004), Gillotin S (2010), Kobet E (2000), Nihira NT (2017)	9
COPS5	0	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
RPTOR	4	CUL4B	8	affinity chromatography technology	Hussain S (2013)	1
CUL1	7	FBXW5	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Busino L (2003), Jeong YT (2013), Chung FZ (2014), Low TY (2014), Reitsma JM (2017)	6
RORA	4	DCAF1	5	affinity chromatography technology, affinity chromatography technology	Lee JM (2012), Lee JM (2012)	2
COPS8	2	COPS4	0	biochemical, affinity chromatography technology, biochemical, biochemical, pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	9
DCAF1	5	MCM10	2	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kaur M (2012), Kaur M (2012), Romani B (2015), Romani B (2015)	4
DCAF8	1	DCAF11	2	biochemical	Kristensen AR (2012)	1
DCAF4L2	3	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017), Wang H (2016)	3
DYRK2	1	DDB1	6	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Maddika S (2009), Maddika S (2009), Maddika S (2009), Maddika S (2009), Hossain D (2017)	5
HDAC2	1	SIN3A	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang Y (2003), Fleischer TC (2003), Fleischer TC (2003), Hakimi MA (2003), Yang L (2003), Laherty CD (1997), Zhang Y (2002), Tong JK (1998), Zhang Y (2005), Nakamura T (2002), Sekhavat A (2007), Zou J (2004), Sun JM (2007), Xue Y (1998), Tsai SC (2002), Brandl A (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hsu DS (2014)	20
IP6K1	5	CUL4A	2	affinity chromatography technology	Rao F (2014)	1
MDM2	2	RASSF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Song MS (2008), Zhang H (2013), Zhang H (2013)	3
RFWD2	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Olma MH (2009)	2
DDA1	1	COPS7B	0	affinity chromatography technology	Olma MH (2009)	1
BRCA1	7	STAT1	1	affinity chromatography technology, pull down, two hybrid	Ouchi T (2000), Ouchi T (2000), Ouchi T (2000)	3
HIST1H3A	3	UNG	1	bioid	Lambert JP (2015)	1
HIST1H3A	3	PHIP	20	bioid	Lambert JP (2015)	1
SAP30	1	RBBP4	3	affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (1998), Zhang Y (1998), Zhang Y (1999), Kuzmichev A (2002), Lai A (2001), Zhang Y (1998), Zhang Y (1998), Hauri S (2016)	8
CUL4A	2	NF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang J (2008), Huang J (2008), Li W (2010)	3
ERCC8	1	GPS1	1	affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003)	2
CUL4A	2	AMBRA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Bennett EJ (2010), Olma MH (2009), Jin J (2006), Antonioli M (2014), Antonioli M (2014), Antonioli M (2014)	6