Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
WBP2NL rs5758550 G 4-hydroxytamoxifen metabolism/PK no among all patients or the subset of CYP2D6*2 carriers (as judged by rs16947). Allele of rs5758550 that authors classified as "enhancer" was not explicitly stated so used the allele from variant annotation of Wang et al (PMID: 3985325) which was referenced. Allele G is not associated with concentrations of 4-hydroxytamoxifen, endoxifen, n-desmethyltamoxifen or tamoxifen in women with Breast Neoplasms as compared to allele A. 28745555 1448640623