PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
ATF3	0	ATF2	1	two hybrid, fluorescent resonance energy transfe, fluorescent resonance energy transfe	Ravasi T (2010), Reinke AW (2013), Reinke AW (2013)	3
DNMT3L	2	DDIT3	1	pull down	Pacaud R (2014)	1
CUL3	17	CUL1	7	affinity chromatography technology, affinity chromatography technology, biochemical	Bennett EJ (2010), Bennett EJ (2010), Wan C (2015)	3
ATF2	1	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
FOSL2	2	JUN	0	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pognonec P (1997), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Li X (2015), Huttlin EL (2017)	6
COPS8	2	COPS7A	0	biochemical, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Huang X (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
CUL3	17	KPNA2	0	affinity chromatography technology	Bennett EJ (2010)	1
DDIT3	1	CREB3L1	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
BATF	0	ATF2	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DDIT3	1	MCMBP	3	two hybrid	Rual JF (2005)	1
ATF4	2	JUN	0	pull down, two hybrid, fluorescent resonance energy transfe, fluorescent resonance energy transfe, imaging technique	Hai T (1991), Bandyopadhyay S (2010), Reinke AW (2013), Reinke AW (2013), Chen TC (2014)	5
EP300	36	FOSL2	2	enzymatic study	Wang WM (2011)	1
CEBPE	0	FOSL1	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
CEBPA	0	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
CEBPE	0	JUN	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
DDIT3	1	TNFSF12	0	two hybrid	Rolland T (2014)	1
EPAS1	6	BATF	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
EPAS1	6	BATF3	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
BACH2	6	MAFF	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Reinke AW (2013), Reinke AW (2013), Huttlin EL (2015), Huttlin EL (2017)	4
DDIT3	1	KPNA2	0	two hybrid	Wang J (2011)	1
DDIT3	1	JUND	2	pull down, affinity chromatography technology, two hybrid	Ubeda M (1999), Ubeda M (1999), Ubeda M (1999)	3
IKBKG	0	PRKN	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Henn IH (2007), Henn IH (2007), Sha D (2010)	3
DNMT3L	2	NFIL3	1	pull down	Pacaud R (2014)	1
MAFF	0	BATF3	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DDIT3	1	BACH1	3	fluorescent resonance energy transfe	Reinke AW (2013)	1
JUN	0	CEBPB	2	affinity chromatography technology	Li X (2015)	1
BATF	0	CEBPG	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
COPS7A	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uhle S (2003), Bennett EJ (2010), Huang X (2016), Reitsma JM (2017)	4
DDIT3	1	VPS37C	3	two hybrid	Rolland T (2014)	1
DDIT3	1	JUNB	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
CREBBP	29	FOS	0	pull down, affinity chromatography technology, two hybrid	Fan S (2002), Bossis G (2005), Patel D (1999)	3
DDIT3	1	SNAPC5	4	two hybrid	Rolland T (2014)	1
NFIL3	1	BATF	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
JUNB	0	EP300	36	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Narayanan K (2004), Narayanan K (2004), Narayanan K (2004), Wang CC (2007), Wang WM (2011)	5
BATF	0	CEBPA	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
JUN	0	BATF	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
ATF4	2	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
JUN	0	CSNK2A1	15	pull down, far western blotting, enzymatic study	Yamaguchi Y (1998), Yamaguchi Y (1998), Uhle S (2003)	3
DNMT3L	2	ATF2	1	pull down	Pacaud R (2014)	1
JUNB	0	ATF2	1	affinity chromatography technology	Huttlin EL (2017)	1
CEBPE	0	CEBPA	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe, pull down	Reinke AW (2013), Reinke AW (2013), Reddy KV (2003)	3
FOSL1	0	EP300	36	affinity chromatography technology, enzymatic study	Crish JF (2008), Wang WM (2011)	2
PRKN	1	CUL1	7	affinity chromatography technology, pull down, affinity chromatography technology	Staropoli JF (2003), Staropoli JF (2003), Gong Y (2014)	3
DDIT3	1	CUL3	17	affinity chromatography technology, biochemical	Huang X (2012), Huang X (2012)	2
ATF2	1	FOS	0	pull down, fluorescent resonance energy transfe, fluorescent resonance energy transfe, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hai T (1991), Reinke AW (2013), Reinke AW (2013), Miyamoto-Sato E (2010), Rolland T (2014), Huttlin EL (2015), Li X (2015), Huttlin EL (2017)	8
CEBPB	2	ATF3	0	affinity chromatography technology	Lee SH (2010)	1
CEBPE	0	DDIT3	1	two hybrid, pull down	Chih DY (2004), Chih DY (2004)	2
HDAC5	4	CSNK2A1	15	affinity chromatography technology	Greco TM (2011)	1
JUNB	0	JUN	0	affinity chromatography technology	Huttlin EL (2017)	1
BATF3	0	JUNB	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe, affinity chromatography technology	Reinke AW (2013), Reinke AW (2013), Huttlin EL (2017)	3
DDIT3	1	RAI1	16	two hybrid	Ravasi T (2010)	1
EP300	36	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Han Y (2008), Mayanil CS (2006), Simone C (2004), Simone C (2004), Simone C (2004), Liu Y (2012), Mizuguchi Y (2012)	7
DBP	1	BATF2	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
DDIT3	1	CSNK2A1	15	pull down, enzymatic study	Ubeda M (2003), Ubeda M (2003)	2
COPS8	2	COPS3	1	biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Min KW (2005), Enchev RI (2010), Sharon M (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	11
DNMT3L	2	ATF4	2	pull down	Pacaud R (2014)	1
ATF2	1	CEBPA	0	two hybrid	Hong S (2004)	1
HDAC5	4	ATF3	0	pull down	Darlyuk-Saadon I (2012)	1
MAPK14	0	HDAC1	4	biochemical	Wan C (2015)	1
EPAS1	6	BATF2	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
KEAP1	0	MCMBP	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Taipale M (2014), Taipale M (2014), Mulvaney KM (2016)	4
BATF	0	DBP	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
FOS	0	CEBPA	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
EPAS1	6	DDIT3	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
CEBPE	0	COPS3	1	two hybrid	Chih DY (2004)	1
HDAC6	0	DDIT3	1	affinity chromatography technology	Ohoka N (2007)	1
CREBBP	29	KPNA2	0	enzymatic study, affinity chromatography technology	Bannister AJ (2000), Ryan CM (2006)	2
FOSL2	2	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
BATF2	0	DDIT3	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ATF4	2	CEBPA	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DDIT3	1	ZSCAN31	1	two hybrid	Ravasi T (2010)	1
ATF3	0	HDAC6	0	two hybrid, affinity chromatography technology, pull down	Darlyuk-Saadon I (2012), Darlyuk-Saadon I (2012), Darlyuk-Saadon I (2012)	3
BACH1	3	HDAC1	4	affinity chromatography technology	Dohi Y (2008)	1
EP300	36	KPNA2	0	enzymatic study	Bannister AJ (2000)	1
HDAC5	4	RPS3A	1	affinity chromatography technology	Greco TM (2011)	1
CEBPB	2	EP300	36	genetic interference, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, imaging technique, affinity chromatography technology	Mink S (1997), Mink S (1997), Mink S (1997), Mink S (1997), Mink S (1997), Deng WG (2004), Deng WG (2004), Deng WG (2003)	8
CREBBP	29	IKBKG	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Verma UN (2004), Verma UN (2004), Verma UN (2004)	3
GABBR1	0	DDIT3	1	affinity chromatography technology, imaging technique	Sauter K (2005), Sauter K (2005)	2
GABBR2	15	ATF4	2	affinity chromatography technology	White JH (2000)	1
DDIT3	1	DDIT3	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
PRKN	1	DDIT3	1	affinity chromatography technology, affinity chromatography technology	Han K (2017), Han K (2017)	2
DDIT3	1	CUL1	7	affinity chromatography technology	Huang X (2012)	1
DNMT3L	2	HOXA5	0	pull down	Pacaud R (2014)	1
BATF	0	ATF3	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
FOSL2	2	JUNB	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mathas S (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	4
DNMT3L	2	JUN	0	pull down	Pacaud R (2014)	1
CEBPE	0	CEBPG	1	two hybrid, pull down, fluorescent resonance energy transfe	Chih DY (2004), Chih DY (2004), Reinke AW (2013)	3
EP300	36	HDAC6	0	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Han Y (2009), Han Y (2009), Liu Y (2012), Kirilyuk A (2012), Girdwood D (2003)	5
DBP	1	CEBPG	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
JUND	2	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study	Kim H (2005), Wang CC (2007), Wang WM (2011)	3
DDIT3	1	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
CEBPG	1	FOS	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
BATF3	0	BACH2	6	fluorescent resonance energy transfe, affinity chromatography technology	Reinke AW (2013), Huttlin EL (2017)	2
MAFF	0	NFIL3	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
KEAP1	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang XJ (2008), Rachakonda G (2008), Rachakonda G (2008), Nioi P (2007), Chew EH (2007), Chew EH (2007), Zhang DD (2005), Furukawa M (2005), Furukawa M (2005), Furukawa M (2005), Zhang DD (2004), Cullinan SB (2004), Kobayashi A (2004), Kobayashi A (2004), McMahon M (2006), Ichikawa T (2009), Lee DF (2009), Wong DP (2010), Wong DP (2010), Lau A (2010), Lau A (2010), Hur W (2010), Bennett EJ (2010), Yao JW (2012), Li Y (2012), Choo YY (2012), Kansanen E (2011), Kansanen E (2011), Niture SK (2013), Hast BE (2014), Cleasby A (2014), Kaspar JW (2012), Kaspar JW (2012), Su C (2015), Su C (2015), Huo L (2015), Dubiel D (2015), Lo SC (2006), Wu G (2017), Villeneuve NF (2013), Villeneuve NF (2013), Villeneuve NF (2013), Dong T (2016)	43
DDIT3	1	HSD17B14	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
MAFG	1	NFIL3	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
FOSL1	0	JUN	0	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, fluorescent resonance energy transfe	Pognonec P (1997), Pognonec P (1997), Kumar NV (2001), Kumar NV (2001), Reinke AW (2013), Reinke AW (2013)	6
DDIT3	1	ATF3	0	affinity chromatography technology, pull down, fluorescent resonance energy transfe, fluorescent resonance energy transfe	Chen BP (1996), Chen BP (1996), Reinke AW (2013), Reinke AW (2013)	4
CUL1	7	COPS8	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Menon S (2008), Bennett EJ (2010), Enchev RI (2012), Reitsma JM (2017)	4
SPOP	1	AMOTL2	5	two hybrid	Zhang P (2017)	1
COPS3	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Reitsma JM (2017)	4
ATF3	0	FOS	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ATF3	0	CREBBP	29	affinity chromatography technology, pull down	Kim HB (2010), Kim HB (2010)	2
HDAC5	4	MAFF	0	two hybrid	Ravasi T (2010)	1
CEBPG	1	ATF2	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
DDIT3	1	BACH2	6	fluorescent resonance energy transfe	Reinke AW (2013)	1
CEBPG	1	ATF4	2	fluorescent resonance energy transfe, two hybrid	Reinke AW (2013), Rolland T (2014)	2
MAFF	0	FOS	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
CUL3	17	ATF2	1	affinity chromatography technology	Bhoumik A (2008)	1
ATF3	0	CEBPE	0	imaging technique, fluorescent resonance energy transfe, fluorescent resonance energy transfe	Lopez AB (2007), Reinke AW (2013), Reinke AW (2013)	3
MAFF	0	RTL6	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DDIT3	1	CREBBP	29	affinity chromatography technology	Park SH (2010)	1
PRKN	1	BACH1	3	affinity chromatography technology	Zenke-Kawasaki Y (2007)	1
ATF2	1	BACH1	3	fluorescent resonance energy transfe	Reinke AW (2013)	1
EP300	36	FOS	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Wang WM (2011), Pekarsky Y (2008), Wang C (2001)	3
JUNB	0	FOSL1	0	two hybrid, fluorescent resonance energy transfe, fluorescent resonance energy transfe	Rual JF (2005), Reinke AW (2013), Reinke AW (2013)	3
GABBR1	0	ATF4	2	two hybrid, affinity chromatography technology	White JH (2000), White JH (2000)	2
DDIT3	1	POLR1D	4	two hybrid	Wang J (2011)	1
CEBPA	0	JUN	0	affinity chromatography technology	Zada AA (2006)	1
DDIT3	1	GP1BA	0	two hybrid	Wang J (2011)	1
DBP	1	CEBPA	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
JUNB	0	BATF	0	two hybrid, fluorescent resonance energy transfe, fluorescent resonance energy transfe, two hybrid, two hybrid	Wang X (1996), Reinke AW (2013), Reinke AW (2013), Rolland T (2014), Yu H (2011)	5
DNMT3L	2	FOSL2	2	pull down	Pacaud R (2014)	1
MAFF	0	ATF3	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DDIT3	1	ATF2	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
DDIT3	1	MAFF	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
ATF3	0	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
DNMT3L	2	JUNB	0	pull down	Pacaud R (2014)	1
DDIT3	1	HOXA5	0	two hybrid	Ravasi T (2010)	1
DBP	1	DDIT3	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe, two hybrid	Reinke AW (2013), Reinke AW (2013), Wang J (2011)	3
DDIT3	1	TRIB3	0	affinity chromatography technology, pull down	Ohoka N (2007), Ohoka N (2007)	2
FOS	0	JUNB	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Reinke AW (2013), Reinke AW (2013), Rolland T (2014), Huttlin EL (2015), Hein MY (2015), Li X (2015), Huttlin EL (2017)	7
BATF3	0	BATF	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DDIT3	1	CEBPA	0	affinity chromatography technology, two hybrid, affinity chromatography technology	Marwarha G (2016), Marwarha G (2016), Marwarha G (2016)	3
CUL1	7	KPNA2	0	affinity chromatography technology	Bennett EJ (2010)	1
JUNB	0	TEDC1	0	affinity chromatography technology	Huttlin EL (2017)	1
ATF2	1	CEBPB	2	affinity chromatography technology	Deb S (2006)	1
ATF3	0	CEBPA	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DDIT3	1	RTL6	1	affinity chromatography technology	Behrends C (2010)	1
EPAS1	6	IKBKG	0	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Nowicka AM (2016), Nowicka AM (2016), Nowicka AM (2016), Nowicka AM (2016), Bracken CP (2005), Bracken CP (2005), Bracken CP (2005), Bracken CP (2005), Bracken CP (2005)	9
ATF3	0	FOSL1	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
EPAS1	6	CREBBP	29	affinity chromatography technology	Steunou AL (2012)	1
RPS3A	1	DDIT3	1	affinity chromatography technology, pull down	Cui K (2000), Cui K (2000)	2
BATF3	0	ATF3	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DDIT3	1	BATF	0	two hybrid, fluorescent resonance energy transfe, fluorescent resonance energy transfe, two hybrid	Rual JF (2005), Reinke AW (2013), Reinke AW (2013), DeGrado-Warren J (2008)	4
CEBPB	2	HDAC1	4	affinity chromatography technology, affinity chromatography technology	Gulbagci NT (2009), Jin J (2011)	2
DDIT3	1	FOS	0	pull down, affinity chromatography technology, fluorescent resonance energy transfe	Ubeda M (1999), Ubeda M (1999), Reinke AW (2013)	3
DNMT3L	2	FOS	0	pull down	Pacaud R (2014)	1
PPIB	1	DDIT3	1	affinity chromatography technology, affinity chromatography technology	Jeong K (2014), Jeong K (2014)	2
CREB3	1	ATF4	2	fluorescent resonance energy transfe	Reinke AW (2013)	1
BATF2	0	CEBPA	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
CSNK2A1	15	HDAC1	4	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology	Pflum MK (2001), Cai R (2001), Sun JM (2007), Zhang M (2011), Joshi P (2013)	5
CUL3	17	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huang X (2016), Huttlin EL (2017)	5
CREB3	1	RPS3A	1	two hybrid	Yu H (2011)	1
FOSL1	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology	Hoffmann E (2005), Hoffmann E (2005)	2
FOSL2	2	BACH2	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ATF4	2	FOS	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe, imaging technique	Reinke AW (2013), Reinke AW (2013), Chen TC (2014)	3
DDIT3	1	FOSL1	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
MAPK14	0	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAFG	1	BATF3	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DDIT3	1	EMSY	3	two hybrid	Rolland T (2014)	1
CREBBP	29	CSNK2A1	15	pull down, far western blotting, affinity chromatography technology	Yamaguchi Y (1998), Yamaguchi Y (1998), Jung SY (2005)	3
GABBR1	0	GABBR2	15	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	White JH (1998), White JH (1998), White JH (1998), Lahaie N (2016)	4
EP300	36	EPAS1	6	pull down, affinity chromatography technology, affinity chromatography technology	Kung AL (2004), Steunou AL (2012), Chen R (2012)	3
BATF3	0	BACH1	3	affinity chromatography technology	Huttlin EL (2017)	1
CEBPA	0	CEBPG	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
CREBBP	29	FOSL1	0	affinity chromatography technology	Tran NQ (2004)	1
FOS	0	JUN	0	pull down, two hybrid, pull down, x-ray crystallography, two hybrid, pull down, two hybrid, two hybrid, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, fluorescent resonance energy transfe, pull down, pull down, imaging technique, pull down, affinity chromatography technology, pull down, pull down, fluorescent resonance energy transfe, pull down, pull down, affinity chromatography technology, biochemical, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ito T (2001), Pognonec P (1997), Pognonec P (1997), Glover JN (1995), Yang X (1999), Nomura N (1993), Finkel T (1993), Finkel T (1993), Venugopal R (1998), Kumar NV (2001), Dumin E (2006), Bandyopadhyay S (2010), Asim M (2010), Asim M (2010), Srivastav RK (2011), Bossis G (2005), Bossis G (2005), Gupta K (2000), Bachmann M (2004), Reinke AW (2013), Miyagi M (2005), Subbaramaiah K (2007), Jang M (2012), Yamaguchi K (2005), Varjosalo M (2013), Miyamoto-Sato E (2010), Miyamoto-Sato E (2010), Varjosalo M (2013), Tang HY (2006), Marden NY (2005), Adler J (2010), Adler J (2010), Adler J (2010), Billiet L (2008), Huttlin EL (2015), Hein MY (2015), Li X (2015), Li X (2015), Huttlin EL (2017)	39
DDIT3	1	GABBR2	15	two hybrid, affinity chromatography technology, imaging technique	Sauter K (2005), Sauter K (2005), Sauter K (2005)	3
JUN	0	HDAC1	4	affinity chromatography technology	Tenbrock K (2006)	1
CEBPG	1	JUN	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
IKBKG	0	CUL1	7	affinity chromatography technology	Orel L (2010)	1
DDIT3	1	KEAP1	0	biochemical	Huang X (2012)	1
COPS3	1	CSNK2A1	15	far western blotting	Uhle S (2003)	1
CUL1	7	RPS3A	1	affinity chromatography technology	Bennett EJ (2010)	1
BATF3	0	ATF2	1	fluorescent resonance energy transfe, affinity chromatography technology	Reinke AW (2013), Huttlin EL (2017)	2
CEBPG	1	FOSL1	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
BATF	0	CEBPE	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
JUN	0	ATF2	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, fluorescent resonance energy transfe, fluorescent resonance energy transfe, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Newell CL (1994), Newell CL (1994), Kara CJ (1990), Hai T (1991), Fuchs SY (1999), Reinke AW (2013), Reinke AW (2013), Miyamoto-Sato E (2010), Hayakawa J (2004), Hein MY (2015), Li X (2015), Huttlin EL (2017)	12
BATF3	0	CEBPA	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DDIT3	1	FANCA	5	affinity chromatography technology	Karras GI (2017)	1
CEBPA	0	FOSL1	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
CUL3	17	MCMBP	3	affinity chromatography technology	Bennett EJ (2010)	1
MAFF	0	BATF2	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DDIT3	1	IKBKG	0	two hybrid	Wang J (2011)	1
ATF3	0	JUNB	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe, affinity chromatography technology	Reinke AW (2013), Reinke AW (2013), Huttlin EL (2017)	3
CEBPB	2	CREBBP	29	pull down	Kovacs KA (2003)	1
ATF3	0	HDAC1	4	affinity chromatography technology, pull down	Li HF (2010), Darlyuk-Saadon I (2012)	2
DDIT3	1	CREB3	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
DDIT3	1	ZBTB25	2	two hybrid	Rolland T (2014)	1
BACH2	6	MAFG	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ATF2	1	CSNK2A1	15	pull down, far western blotting	Yamaguchi Y (1998), Yamaguchi Y (1998)	2
MAPK14	0	ATF2	1	enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Raingeaud J (1995), Raingeaud J (1995), Chen Z (2001), Pillai VB (2011), Pillai VB (2011), Gianni M (2006), Deacon K (1997), Sudo T (2000), Mo JS (2010), Uddin S (2002), Stein B (1997), Yuan ZQ (2003), Coxon PY (2003), Li H (2001), Sun L (2007), Grimsey NJ (2015), Tang J (2008), Dixon DA (2006), Chen G (2000), Frantz B (1998), Tesker M (2016), Hwang SG (2014), Camps M (1998), Bakin AV (2002), Bulavin DV (1999)	25
EPAS1	6	DBP	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
BATF2	0	ATF4	2	fluorescent resonance energy transfe	Reinke AW (2013)	1
DDIT3	1	BATF3	0	fluorescent resonance energy transfe, two hybrid	Reinke AW (2013), Rolland T (2014)	2
COPS7A	0	CSNK2A1	15	affinity chromatography technology, far western blotting, enzymatic study	Uhle S (2003), Uhle S (2003), Uhle S (2003)	3
BATF3	0	RTL6	1	affinity chromatography technology	Huttlin EL (2017)	1
EP300	36	DDIT3	1	affinity chromatography technology, affinity chromatography technology, pull down	Jeong K (2014), Ohoka N (2007), Ohoka N (2007)	3
CUL3	17	COPS8	2	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Schumacher FR (2015)	2
CEBPA	0	HDAC1	4	affinity chromatography technology, biochemical, imaging technique, affinity chromatography technology	Duan H (2005), Matsunaga N (2012), Matsunaga N (2012), Girard N (2013)	4
BATF2	0	CEBPG	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
SNAPC5	4	BATF	0	two hybrid	Rual JF (2005)	1
BACH1	3	MAFG	1	affinity chromatography technology, fluorescent resonance energy transfe, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Dohi Y (2008), Reinke AW (2013), Reinke AW (2013), Hein MY (2015), Huttlin EL (2017)	5
CREBBP	29	JUNB	0	affinity chromatography technology	Tran NQ (2004)	1
ATF4	2	EP300	36	affinity chromatography technology, pull down, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology	Lassot I (2005), Lassot I (2005), Lassot I (2005), Deng WG (2004), Deng WG (2004), Ohoka N (2007), Deng WG (2003)	7
BATF3	0	CEBPE	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DBP	1	ATF3	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
DDIT3	1	SSX3	0	two hybrid	Ravasi T (2010)	1
FOS	0	CSNK2A1	15	pull down, far western blotting	Yamaguchi Y (1998), Yamaguchi Y (1998)	2
BATF3	0	DBP	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
CREBBP	29	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Crusselle-Davis VJ (2007), Dohda T (2004), Dohda T (2004)	3
ATF3	0	JUN	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, fluorescent resonance energy transfe, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Pearson AG (2003), Chen BP (1996), Hai T (1991), Filen S (2010), Reinke AW (2013), Reinke AW (2013), Hein MY (2015), Li X (2015)	8
DDIT3	1	TEDC1	0	affinity chromatography technology, two hybrid	Behrends C (2010), DeGrado-Warren J (2008)	2
MAFG	1	MAFF	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
EPAS1	6	JUN	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
CEBPE	0	FOS	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
DDIT3	1	MAFG	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
BATF3	0	JUND	2	affinity chromatography technology	Huttlin EL (2017)	1
DDIT3	1	JUN	0	pull down, affinity chromatography technology, fluorescent resonance energy transfe	Ubeda M (1999), Ubeda M (1999), Reinke AW (2013)	3
BATF	0	ATF4	2	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
HDAC1	4	CREBBP	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mayanil CS (2006), Chuang HC (2006), Chuang HC (2006)	3
ATF2	1	FOSL1	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
ATF4	2	FOSL1	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
MAPK14	0	HOXA5	0	affinity chromatography technology	Huttlin EL (2015)	1
HDAC5	4	HDAC1	4	affinity chromatography technology	Greco TM (2011)	1
JUN	0	KPNA2	0	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
DDIT3	1	F2	2	two hybrid	Wang J (2011)	1
CDK6	0	KEAP1	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
COPS3	1	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	5
MAFG	1	ATF3	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
HDAC5	4	DDIT3	1	affinity chromatography technology	Ohoka N (2007)	1
CDK6	0	DDIT3	1	enzymatic study	Anders L (2011)	1
CEBPB	2	CEBPA	0	pull down, pull down	Cao Z (1991), Lin L (2005)	2
BATF2	0	JUN	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DNMT3L	2	ATF3	0	pull down	Pacaud R (2014)	1
DDIT3	1	HDAC1	4	affinity chromatography technology, affinity chromatography technology	Alter J (2012), Ohoka N (2007)	2
DDIT3	1	ATPAF2	1	two hybrid	Rolland T (2014)	1
ATF4	2	DDIT3	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe, two hybrid	Reinke AW (2013), Reinke AW (2013), DeGrado-Warren J (2008)	3
BATF3	0	ATF4	2	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
CUL3	17	RPS3A	1	affinity chromatography technology	Bennett EJ (2010)	1
ATF4	2	JUNB	0	two hybrid	Wang J (2011)	1
CEBPG	1	CREB3	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
DDIT3	1	DGCR2	4	two hybrid	Wang J (2011)	1
DDIT3	1	FOSL2	2	two hybrid	Rolland T (2014)	1
DDIT3	1	COPS8	2	affinity chromatography technology, biochemical	Huang X (2012), Huang X (2012)	2
ZBTB25	2	SSX3	0	two hybrid	Ravasi T (2010)	1
ATF4	2	CREBBP	29	pull down, affinity chromatography technology, imaging technique	Liang G (1997), Venza I (2001), Chen TC (2014)	3
MAPK14	0	EP300	36	pull down, enzymatic study, affinity chromatography technology	Pillai VB (2011), Pillai VB (2011), Saha RN (2007)	3
FOSL2	2	JUND	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
COPS7A	0	DDIT3	1	affinity chromatography technology	Huang X (2012)	1
DDIT3	1	AMOTL2	5	two hybrid	Rolland T (2014)	1
HDAC1	4	EMSY	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Joshi P (2013), Hein MY (2015), Varier RA (2016), Huttlin EL (2017)	4
DDIT3	1	CEBPB	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hattori T (2003), Hattori T (2003), Fawcett TW (1996), Fawcett TW (1996), Behrends C (2010), Ron D (1992)	6
ATF3	0	CEBPG	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
CREBBP	29	ATF2	1	pull down, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Sano Y (1998), Sano Y (1998), Sano Y (1998), Sano Y (1998), Deb S (2006), Merika M (1998), Johnson J (2007), Venza I (2001)	8
DDIT3	1	COPS3	1	biochemical	Huang X (2012)	1
FOS	0	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
MAPK14	0	CSNK2A1	15	affinity chromatography technology, pull down	Sayed M (2000), Sayed M (2000)	2
DDIT3	1	ZC3H14	3	two hybrid	Rolland T (2014)	1
BATF3	0	CEBPG	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DDIT3	1	GIPC1	1	two hybrid	DeGrado-Warren J (2008)	1
ATF2	1	JUND	2	affinity chromatography technology	Huttlin EL (2017)	1
DNMT3L	2	HDAC1	4	pull down, pull down, pull down, pull down, affinity chromatography technology	Aapola U (2002), Aapola U (2002), Deplus R (2002), Deplus R (2002), Deplus R (2002)	5
DDIT3	1	LMO2	2	two hybrid	Rolland T (2014)	1
DDIT3	1	NFIL3	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
CREB3L1	1	CREB3	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
CEBPG	1	DDIT3	1	two hybrid, affinity chromatography technology, two hybrid	Rual JF (2005), Hattori T (2003), Rolland T (2014)	3
FOSL2	2	ATF2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
COPS3	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
BATF2	0	JUNB	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe, two hybrid	Reinke AW (2013), Reinke AW (2013), Wang J (2011)	3
DDIT3	1	CCDC153	0	two hybrid	Rolland T (2014)	1
DDIT3	1	SPOP	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Zhang P (2014), Zhang P (2014)	3
ATF4	2	ATF2	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
CREB3	1	ATF3	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
ATF4	2	CEBPE	0	imaging technique, fluorescent resonance energy transfe, fluorescent resonance energy transfe	Lopez AB (2007), Reinke AW (2013), Reinke AW (2013)	3
EPAS1	6	CREB3L1	1	affinity chromatography technology	Cui M (2015)	1
NFIL3	1	AMOTL2	5	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
MAPK14	0	JUN	0	enzymatic study	Thakur N (2014)	1
EP300	36	JUN	0	pull down, biochemical, x-ray crystallography, affinity chromatography technology, pull down, enzymatic study, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Campbell KM (2002), Campbell KM (2002), Campbell KM (2002), Subbaramaiah K (2002), Duyndam MC (1999), Wang WM (2011), Deng WG (2004), Deng WG (2004), Cheng SE (2011), Cheng SE (2011), Kim BK (2014), Vries RG (2001), Deng WG (2003), Liu L (2017), Liu L (2017)	15
DNMT3L	2	FOSL1	0	pull down	Pacaud R (2014)	1
CEBPB	2	CEBPG	1	pull down	Gao H (2002)	1
JUN	0	CREB3	1	pull down	Miyamoto-Sato E (2010)	1
BACH1	3	MAFF	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Reinke AW (2013), Reinke AW (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	5
ATF4	2	ATF3	0	affinity chromatography technology, fluorescent resonance energy transfe, fluorescent resonance energy transfe	Wang Q (2009), Reinke AW (2013), Reinke AW (2013)	3
JUN	0	JUND	2	affinity chromatography technology	Li X (2015)	1
CREBBP	29	JUN	0	pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, far western blotting	Sano Y (1998), Sano Y (1998), Merika M (1998), Duyndam MC (1999), Johnson J (2007), Yamaguchi K (2005), Tsai LN (2008), Arias J (1994)	8
MAPK14	0	DDIT3	1	enzymatic study	Wang XZ (1996)	1
EP300	36	ATF2	1	biochemical	Duyndam MC (1999)	1
SPOP	1	CUL3	17	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li C (2011), Cummings CM (2009), Choo YY (2011), Choo YY (2012), Plafker KS (2009), Kwon JE (2006), Kwon JE (2006), Wang J (2011), Wimuttisuk W (2014), Theurillat JP (2014), Sakaue T (2017)	11
CEBPE	0	BATF2	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
JUNB	0	JUND	2	affinity chromatography technology	Huttlin EL (2017)	1
IKBKG	0	COPS3	1	affinity chromatography technology	Hong X (2001)	1
BATF3	0	JUN	0	pull down, fluorescent resonance energy transfe, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Iacobelli M (2000), Reinke AW (2013), Reinke AW (2013), Li X (2015), Huttlin EL (2017)	5
FOS	0	JUND	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kumar NV (2001), Miyamoto-Sato E (2010), Huttlin EL (2015), Hein MY (2015), Li X (2015), Huttlin EL (2017)	6
ATF3	0	JUND	2	pull down, affinity chromatography technology	Chu HM (1994), Chu HM (1994)	2
TRIB3	0	ATF4	2	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid	Bowers AJ (2003), Bowers AJ (2003), Zhou Y (2008), Zhou Y (2008), Zhou Y (2008), Rolland T (2014)	6