PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
HIST1H3A	3	DDB1	6	affinity chromatography technology, pull down	Higa LA (2006), Higa LA (2006)	2
DNMT3B	3	RTF1	3	affinity chromatography technology	Rigbolt KT (2011)	1
CDC73	1	MYC	2	affinity chromatography technology, unspecified method	Jaenicke LA (2016), Jaenicke LA (2016)	2
CDC73	1	SUV39H1	0	affinity chromatography technology, affinity chromatography technology	Takahashi A (2011), Takahashi A (2011)	2
CDC73	1	PAF1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rozenblatt-Rosen O (2005), Rozenblatt-Rosen O (2005), Nordick K (2008), Nordick K (2008), Kim J (2010), Mak AB (2010), Mak AB (2010), Takahashi A (2011), Takahashi A (2011), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Herr P (2015), Huttlin EL (2017)	16
USP7	14	DNMT1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, affinity chromatography technology, enzymatic study	Sowa ME (2009), Felle M (2011), Felle M (2011), Felle M (2011), Felle M (2011), Felle M (2011), Qin W (2011), Qin W (2011), Du Z (2010), Du Z (2010), Du Z (2010), Du Z (2010), Ma H (2012), Hein MY (2015), Cheng J (2015), Cheng J (2015), Cheng J (2015), Cheng J (2015), Cheng J (2015)	19
PRMT5	3	HIST1H3A	3	enzymatic study, enzymatic study, enzymatic study, enzymatic study	Pal S (2003), Amente S (2005), Pal S (2004), Migliori V (2012)	4
HIST1H3A	3	LEO1	3	affinity chromatography technology	Wu J (2012)	1
TRIM28	1	DNMT3A	17	affinity chromatography technology	Quenneville S (2011)	1
DNMT1	5	DNMT3A	17	affinity chromatography technology, pull down, affinity chromatography technology	Kim GD (2002), Kim GD (2002), Rigbolt KT (2011)	3
HIC1	1	EED	1	affinity chromatography technology	Boulay G (2012)	1
EHMT2	4	DNMT3A	17	unspecified method, enzymatic study	Chang Y (2011), Chang Y (2011)	2
CDC73	1	DNMT3B	3	affinity chromatography technology, affinity chromatography technology	Rigbolt KT (2011), Rigbolt KT (2011)	2
DNMT1	5	SUV39H1	0	affinity chromatography technology, affinity chromatography technology	Fuks F (2003), Esteve PO (2006)	2
EZH2	4	HIST1H3A	3	enzymatic study, enzymatic study, affinity chromatography technology	Martin C (2006), Cha TL (2005), Cha TL (2005)	3
LEO1	3	RTF1	3	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, genetic interference	Nordick K (2008), Kim J (2010), Havugimana PC (2012), Wan C (2015), Horlbeck MA (2018)	5
SETDB1	3	DNMT3A	17	affinity chromatography technology	Li H (2006)	1
SUV39H1	0	DNMT3A	17	pull down, affinity chromatography technology	Fuks F (2003), Fuks F (2003)	2
UHRF1	3	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Achour M (2008), Achour M (2008), Achour M (2009), Unoki M (2004), Unoki M (2004), Ma H (2012)	6
DNMT3B	3	POLR2C	0	affinity chromatography technology	Rigbolt KT (2011)	1
TRIM25	5	MYC	2	affinity chromatography technology	Choudhury NR (2017)	1
CUL4B	8	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Jin J (2006), Wang H (2006), Higa LA (2006), Higa LA (2006), Kawajiri K (2009), Bennett EJ (2010), Havugimana PC (2012), Ji Q (2014), Wan C (2015), Hein MY (2015), Mo Y (2017), Mo Y (2017), Yang Y (2015), Yang Y (2015), Yang Y (2015), Higa LA (2006), Higa LA (2006), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007)	23
USP7	14	RB1	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Bhattacharya S (2014), Bhattacharya S (2014), Bhattacharya S (2014), Bhattacharya S (2014)	4
DNMT3A	17	UHRF2	1	affinity chromatography technology	Zhang J (2011)	1
UHRF1	3	DNMT1	5	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology	Achour M (2008), Achour M (2008), Achour M (2008), Achour M (2008), Jin W (2010), Achour M (2009), Felle M (2011), Felle M (2011), Felle M (2011), Felle M (2011), Qin W (2011), Du Z (2010), Du Z (2010), Zhang J (2011), Bostick M (2007), Bostick M (2007), Hervouet E (2010), Hervouet E (2010), Bashtrykov P (2014), De Vos M (2014), De Vos M (2014), Qin W (2015), Myrianthopoulos V (2016), Fang J (2016), Ferry L (2017)	25
EZH2	4	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	van der Vlag J (1999), van der Vlag J (1999), Caretti G (2004), Tong ZT (2012), Tong ZT (2012), Su L (2012), Su L (2012), Wan C (2015)	8
UHRF2	1	UBE2I	0	affinity chromatography technology	Oh Y (2013)	1
TRIM28	1	DNMT3B	3	affinity chromatography technology	Quenneville S (2011)	1
CDC73	1	LEO1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Rozenblatt-Rosen O (2005), Rozenblatt-Rosen O (2005), Rozenblatt-Rosen O (2005), Nordick K (2008), Rozenblatt-Rosen O (2009), Mak AB (2010), Mak AB (2010), Takahashi A (2011), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017), Horlbeck MA (2018)	15
PIAS2	2	HIC1	1	enzymatic study, imaging technique	Stankovic-Valentin N (2007), Sun L (2013)	2
EED	1	5430	0	affinity chromatography technology	Cao Q (2014)	1
DNMT3A	17	ZBTB17	2	affinity chromatography technology, affinity chromatography technology	Brenner C (2005), Hervouet E (2009)	2
HIC1	1	EZH2	4	affinity chromatography technology	Boulay G (2012)	1
USP7	14	UHRF1	3	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Felle M (2011), Felle M (2011), Felle M (2011), Felle M (2011), Qin W (2011), Qin W (2011), Ma H (2012), Ma H (2012), Ma H (2012), Chen H (2013), Nishiyama A (2013), Hein MY (2015), Zhang ZM (2015), Zhang ZM (2015), Zhang ZM (2015), Pfoh R (2015), Pfoh R (2015), Ferry L (2017)	18
DNMT1	5	DNMT3B	3	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, genetic interference, affinity chromatography technology, affinity chromatography technology	Lehnertz B (2003), Kim GD (2002), Kim GD (2002), Geiman TM (2004), Woloszynska-Read A (2007), OHagan HM (2011), Rigbolt KT (2011)	7
MPHOSPH8	1	DNMT3A	17	unspecified method, affinity chromatography technology, affinity chromatography technology, x-ray crystallography	Chang Y (2011), Chang Y (2011), Chang Y (2011), Chang Y (2011)	4
POLR2C	0	CTR9	10	affinity chromatography technology, affinity chromatography technology	Nordick K (2008), Hein MY (2015)	2
POLR2C	0	POLR2H	0	pull down, pull down, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Ayguen O (2008), Wan C (2015)	4
UHRF1	3	DNMT3B	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Meilinger D (2009), Meilinger D (2009), Zhang J (2011)	3
CBX1	0	TRIM28	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Nielsen AL (2001), Chang CW (2008), Chang CW (2008), Ryan RF (1999), Rosnoblet C (2011), Moriyama T (2015), Huttlin EL (2017), Hauri S (2016)	8
RB1	2	TFAP2A	1	pull down, affinity chromatography technology	Batsche E (1998), Batsche E (1998)	2
EHMT2	4	EHMT1	18	affinity chromatography technology, affinity chromatography technology	Bantscheff M (2011), Hauri S (2016)	2
DNMT3B	3	LEO1	3	affinity chromatography technology	Rigbolt KT (2011)	1
PAF1	6	DNMT3B	3	affinity chromatography technology, affinity chromatography technology	Rigbolt KT (2011), Rigbolt KT (2011)	2
PAF1	6	DNMT3A	17	affinity chromatography technology, affinity chromatography technology	Rigbolt KT (2011), Rigbolt KT (2011)	2
HDAC1	4	TRIM28	1	affinity chromatography technology, affinity chromatography technology, biochemical	Allouch A (2011), Chen L (2012), Kristensen AR (2012)	3
SUV39H1	0	HIST1H3A	3	enzymatic study, enzymatic study, enzymatic study	Carbone R (2006), Kamoi K (2006), Mal AK (2006)	3
5430	0	PRMT5	3	affinity chromatography technology, enzymatic study	Zhao DY (2016), Zhao DY (2016)	2
HIST1H3A	3	DAXX	5	affinity chromatography technology	Huttlin EL (2017)	1
EZH2	4	PRMT5	3	two hybrid	Weimann M (2013)	1
CUL4B	8	EZH2	4	affinity chromatography technology	Yang Y (2015)	1
CUL4B	8	CBX5	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015)	4
RBX1	2	CUL4B	8	affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, imaging technique	Dias DC (2002), Ji Q (2014), Huang DT (2009), Hein MY (2015), Yang Y (2015)	5
HIST1H3A	3	EED	1	far western blotting	Tie F (2007)	1
DNMT3A	17	CBX5	3	affinity chromatography technology, affinity chromatography technology	Lehnertz B (2003), Smallwood A (2007)	2
HDAC1	4	SPI1	1	affinity chromatography technology, pull down, affinity chromatography technology	Suzuki M (2003), Suzuki M (2006), Kihara-Negishi F (2001)	3
RBX1	2	CBX5	3	affinity chromatography technology	Yang Y (2015)	1
UBE2I	0	RB1	2	enzymatic study, pull down	Ledl A (2005), Ledl A (2005)	2
UBE2I	0	HDAC1	4	enzymatic study	Citro S (2013)	1
SALL3	3	DNMT3A	17	affinity chromatography technology, affinity chromatography technology	Shikauchi Y (2009), Shikauchi Y (2009)	2
SP100	4	CBX1	0	two hybrid	Seeler JS (1998)	1
TFAP2A	1	UBE2I	0	two hybrid	Eloranta JJ (2002)	1
DAXX	5	USP7	14	pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tang J (2006), Tang J (2006), Tang J (2006), Tang J (2006), Song MS (2008), Giovinazzi S (2013), Giovinazzi S (2013), Giovinazzi S (2013), Kumar N (2013)	9
EHMT2	4	CBX1	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Spektor TM (2009), Chin HG (2007), Roopra A (2004), Hauri S (2016)	4
HIST1H3A	3	CDC73	1	affinity chromatography technology, affinity chromatography technology	Wu J (2012), Wu J (2012)	2
TERF2IP	1	DNMT3A	17	two hybrid	Lee OH (2011)	1
SUV39H1	0	CBX4	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Sewalt RG (2002), Sewalt RG (2002), Sewalt RG (2002), Sewalt RG (2002), Yang L (2011)	5
DDB1	6	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Ji Q (2014), Ji Q (2014), Zhao R (2014), Romani B (2016)	4
5430	0	LEO1	3	pull down, pull down	Kim J (2010), Kim J (2010)	2
HIST1H3E	0	PRMT5	3	biochemical, affinity chromatography technology	Campos EI (2015), Campos EI (2015)	2
PIAS2	2	PIAS1	4	imaging technique	Chen TC (2014)	1
DNMT3B	3	HIC1	1	affinity chromatography technology, affinity chromatography technology	Zeng S (2016), Zeng S (2016)	2
DAXX	5	SUV39H1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hein MY (2015), He Q (2015), He Q (2015)	3
CBX5	3	TRIM28	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nielsen AL (2002), Cammas F (2002), Cammas F (2002), Nielsen AL (2001), Lechner MS (2000), Lechner MS (2005), Lechner MS (2005), Lechner MS (2005), Lechner MS (2005), Ryan RF (1999), Rosnoblet C (2011), Hu C (2012), Hu C (2012), White D (2012), Nozawa RS (2010), Kubota S (2013), Kubota S (2013), Kubota S (2013), Garvin AJ (2013), Huttlin EL (2017), Hauri S (2016)	21
CBX5	3	RB1	2	affinity chromatography technology, affinity chromatography technology	Nielsen SJ (2001), Dasgupta P (2004)	2
CTR9	10	5430	0	affinity chromatography technology	Hein MY (2015)	1
HDAC1	4	UHRF2	1	affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Unoki M (2004), Unoki M (2004), Mori T (2011), Zeng S (2017), Zeng S (2017), Lai M (2016)	6
UHRF2	1	HIST1H3A	3	unspecified method, affinity chromatography technology	Zhang J (2011), Zhang T (2017)	2
CTR9	10	RTF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical	Nordick K (2008), Kim J (2010), Kim J (2010), Havugimana PC (2012), Wan C (2015)	5
DNMT3A	17	TCL1A	0	two hybrid	Rolland T (2014)	1
DNMT3B	3	CBX5	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Lehnertz B (2003), Lehnertz B (2003), Geiman TM (2004), Geiman TM (2004), Kashiwagi K (2011), Smallwood A (2007)	6
8339	0	DNMT3A	17	bioid	Lambert JP (2015)	1
DDB1	6	CBX5	3	affinity chromatography technology	Yang Y (2015)	1
CBX4	1	RB1	2	genetic interference, affinity chromatography technology	Dahiya A (2001), Dahiya A (2001)	2
DNMT3B	3	SUV39H1	0	pull down, pull down	Geiman TM (2004), Geiman TM (2004)	2
8339	0	UHRF1	3	bioid	Lambert JP (2015)	1
UHRF2	1	CUL4B	8	affinity chromatography technology	Lai M (2016)	1
HIST1H3E	0	DNMT3A	17	pull down, far western blotting	Zhang Y (2010), Zhang Y (2010)	2
8339	0	EHMT2	4	bioid	Lambert JP (2015)	1
HIST1H3A	3	CBX1	0	affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, x-ray crystallography	Wysocka J (2005), Wysocka J (2005), Kutney SN (2004), Schneider R (2004), Nielsen PR (2002)	5
HDAC1	4	NRIP1	4	pull down	Castet A (2004)	1
CUL4B	8	HDAC1	4	affinity chromatography technology, affinity chromatography technology, biochemical	Ji Q (2014), Ji Q (2014), Ji Q (2014)	3
MYC	2	UBE2I	0	genetic interference	Toyoshima M (2012)	1
CUL4B	8	DNMT3A	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015)	5
DNMT3B	3	CBX1	0	affinity chromatography technology	Kashiwagi K (2011)	1
CBX1	0	EHMT1	18	affinity chromatography technology	Hauri S (2016)	1
CUL4B	8	CBX1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015)	4
ZFP57	1	DNMT1	5	affinity chromatography technology	Quenneville S (2011)	1
HIST1H3A	3	DNMT3B	3	unspecified method, pull down	Sankaran SM (2016), Sankaran SM (2016)	2
5430	0	POLR2C	0	pull down, pull down, pull down, biochemical, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Knuesel MT (2009), Havugimana PC (2012), Ayguen O (2008), Wan C (2015)	6
DNMT3A	17	POLR2C	0	affinity chromatography technology	Rigbolt KT (2011)	1
RB1	2	SUV39H1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Nielsen SJ (2001), Nielsen SJ (2001), Vandel L (2001), Vandel L (2001), Vandel L (2001)	5
8339	0	MPHOSPH8	1	bioid	Lambert JP (2015)	1
HDAC1	4	EHMT1	18	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
EZH2	4	DNMT3B	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vire E (2006), Vire E (2006), Vire E (2006), OHagan HM (2011), Gong C (2015)	5
DNMT3A	17	HDAC1	4	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Fuks F (2001), Fuks F (2001), Fuks F (2001), Hervouet E (2009)	4
DNMT1	5	UHRF2	1	affinity chromatography technology, affinity chromatography technology	Zhang J (2011), Lai M (2016)	2
DNMT3A	17	MYC	2	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brenner C (2005), Brenner C (2005), Brenner C (2005), Brenner C (2005), Hervouet E (2009)	5
POLR2C	0	PRMT5	3	affinity chromatography technology	Ayguen O (2008)	1
USP7	14	UHRF2	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Hayes SD (2012), Liu Y (2016), Lai M (2016)	3
DDB1	6	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down	Wang H (2006), Kapetanaki MG (2006), Hu J (2004), Ahn J (2010), Fischer ES (2011), Groisman R (2006)	6
EED	1	CBX4	1	affinity chromatography technology	Cao Q (2014)	1
5430	0	DDB1	6	affinity chromatography technology	Fousteri M (2006)	1
EED	1	EHMT1	18	unspecified method, affinity chromatography technology	Guil S (2012), Cao Q (2014)	2
EHMT2	4	UHRF2	1	affinity chromatography technology, affinity chromatography technology	Zhang J (2011), Lai M (2016)	2
DNMT3B	3	HDAC1	4	biochemical, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Geiman TM (2004), Suzuki M (2006), Geiman TM (2004), Geiman TM (2004), Cai Y (2014)	5
EZH2	4	EHMT2	4	affinity chromatography technology	Hein MY (2015)	1
DNMT3A	17	DNMT3B	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ling Y (2004), Lehnertz B (2003), Kim GD (2002), Kim GD (2002), Kashiwagi K (2011), Kashiwagi K (2011), Huttlin EL (2017)	7
RB1	2	HDAC1	4	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Dick FA (2000), Fuks F (2000), Puri PL (2001), Puri PL (2001), Wang S (2002), Luo RX (1998), Luo RX (1998), Lai A (1999), Lai A (1999), Ferreira R (1998), Kimura H (2003), Qiu Z (2008), Fedele M (2006), Brown VD (2002), Khan MM (2001), Dasgupta P (2004), Chang YC (2001), Dahiya A (2000), Zhang HS (2000), Tokitou F (1999), Nguyen DX (2004), Takaki T (2004), Magnaghi-Jaulin L (1998), Magnaghi-Jaulin L (1998), Brehm A (1998), Brehm A (1998), Brehm A (1998), Sun JM (2007), Fan LX (2012), Harbour JW (1999), Brehm A (1999), Joshi P (2013), Chen TT (2000), Chen TT (2000), Chen TT (2000), Chen TT (2000)	36
LEO1	3	PAF1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, biochemical, affinity chromatography technology	Rozenblatt-Rosen O (2005), Nordick K (2008), Nordick K (2008), Nordick K (2008), Kim J (2010), Mak AB (2010), Mak AB (2010), Takahashi A (2011), Havugimana PC (2012), Rolland T (2014), Wan C (2015), Hein MY (2015)	12
DNMT3A	17	SP100	4	two hybrid	Rolland T (2014)	1
UHRF1	3	UHRF2	1	affinity chromatography technology	Ma H (2012)	1
ZFP57	1	DNMT3A	17	affinity chromatography technology	Quenneville S (2011)	1
HDAC1	4	DAXX	5	far western blotting, pull down, affinity chromatography technology	Li H (2000), Li H (2000), Li H (2000)	3
5430	0	POLR2H	0	pull down, pull down, pull down, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Knuesel MT (2009), Wu W (2007), Wan C (2015)	5
HIST1H3A	3	EHMT2	4	pull down, enzymatic study, enzymatic study	Chin HG (2005), Chin HG (2005), Huang J (2010)	3
PAF1	6	RTF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical	Nordick K (2008), Nordick K (2008), Kim J (2010), Kim J (2010), Havugimana PC (2012), Wan C (2015)	6
DNMT3A	17	POLR2H	0	affinity chromatography technology	Rigbolt KT (2011)	1
CUL4B	8	DNMT3B	3	affinity chromatography technology, affinity chromatography technology, pull down	Yang Y (2015), Yang Y (2015), Yang Y (2015)	3
UHRF1	3	PRMT5	3	affinity chromatography technology, affinity chromatography technology	Sheng Y (2016), Sheng Y (2016)	2
ZBTB17	2	MYC	2	pull down, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Staller P (2001), Peukert K (1997), Peukert K (1997), Peukert K (1997), Herold S (2008), Si J (2010), Si J (2010), Gordan JD (2007), Gordan JD (2007), Hervouet E (2009), Hervouet E (2009), Patel JH (2006), Patel JH (2006), Staller P (2001), Vo BT (2016), Vo BT (2016)	16
DNMT3A	17	PTGES3	0	two hybrid, pull down	Zhang X (1996), Zhang X (1996)	2
LEO1	3	CTR9	10	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rozenblatt-Rosen O (2005), Nordick K (2008), Nordick K (2008), Kim J (2010), Mak AB (2010), Mak AB (2010), Ouna BA (2012), Havugimana PC (2012), Wan C (2015), Hein MY (2015), Hein MY (2015), Boldt K (2016)	12
DNMT3A	17	CBX1	0	pull down	Fuks F (2003)	1
TRIM28	1	DNMT1	5	affinity chromatography technology, affinity chromatography technology	Quenneville S (2011), Cui S (2011)	2
EZH2	4	EHMT1	18	unspecified method	Guil S (2012)	1
DNMT3B	3	UBE2I	0	two hybrid, pull down	Kang ES (2001), Kang ES (2001)	2
DNMT3A	17	5430	0	affinity chromatography technology	Rigbolt KT (2011)	1
RBX1	2	DNMT3A	17	affinity chromatography technology	Yang Y (2015)	1
NRIP1	4	DNMT3B	3	affinity chromatography technology, pull down, imaging technique	Kiskinis E (2007), Kiskinis E (2007), Kiskinis E (2007)	3
EED	1	EHMT2	4	affinity chromatography technology	Cao Q (2014)	1
MYC	2	TFAP2A	1	affinity chromatography technology, pull down	Gaubatz S (1995), Gaubatz S (1995)	2
CBX5	3	EHMT1	18	affinity chromatography technology	Nozawa RS (2010)	1
HIST1H3A	3	CTR9	10	affinity chromatography technology, affinity chromatography technology	Wu J (2012), Wu J (2012)	2
UHRF2	1	CDC73	1	affinity chromatography technology	Lai M (2016)	1
DNMT3B	3	UHRF2	1	affinity chromatography technology	Zhang J (2011)	1
EZH2	4	DNMT1	5	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vire E (2006), Vire E (2006), Vire E (2006), Xu B (2011), OHagan HM (2011)	5
PIAS1	4	HIC1	1	enzymatic study	Stankovic-Valentin N (2007)	1
RTF1	3	CDC73	1	affinity chromatography technology	Kim J (2010)	1
HIST1H3E	0	CBX1	0	affinity chromatography technology	Campos EI (2015)	1
CBX1	0	CBX5	3	affinity chromatography technology, affinity chromatography technology, pull down, pull down, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nielsen AL (2001), Nielsen AL (2001), Nielsen AL (2001), Nielsen AL (2001), Mateos-Langerak J (2007), Mateos-Langerak J (2007), Rosnoblet C (2011), Nozawa RS (2010), Hauri S (2016), Hauri S (2016)	10
DNMT3L	2	DNMT3B	3	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, pull down, imaging technique	Hata K (2002), Ooi SK (2007), Margot JB (2003), Suetake I (2004), Suetake I (2004), Suetake I (2004), Pacaud R (2014), Pacaud R (2014)	8
SP100	4	CBX5	3	two hybrid, pull down, pull down, unspecified method, unspecified method, affinity chromatography technology, two hybrid, two hybrid	Seeler JS (1998), Seeler JS (1998), Seeler JS (2001), Lechner MS (2005), Lechner MS (2005), Lechner MS (2005), Rolland T (2014), Yu H (2011)	8
UBE2I	0	SP100	4	enzymatic study, pull down, two hybrid, enzymatic study, enzymatic study, enzymatic study	Knipscheer P (2008), Knipscheer P (2008), Bandyopadhyay S (2010), Pelisch F (2010), Meulmeester E (2008), Knipscheer P (2007)	6
USP7	14	MYC	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Tavana O (2016), Tavana O (2016), Tavana O (2016), Tavana O (2016)	4
UHRF2	1	EED	1	affinity chromatography technology	Lai M (2016)	1
DNMT3A	17	RTF1	3	affinity chromatography technology	Rigbolt KT (2011)	1
HDAC1	4	EHMT2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Joshi P (2013), Hein MY (2015), Huttlin EL (2017)	3
EZH2	4	TRIM25	5	affinity chromatography technology	Cao Q (2014)	1
SUV39H1	0	SETDB1	3	affinity chromatography technology	Huttlin EL (2017)	1
EZH2	4	DNMT3A	17	pull down, affinity chromatography technology, affinity chromatography technology	Vire E (2006), Vire E (2006), Vire E (2006)	3
TRIM25	5	PTGES3	0	affinity chromatography technology	Choudhury NR (2017)	1
DDB1	6	DNMT3A	17	affinity chromatography technology, pull down	Yang Y (2015), Yang Y (2015)	2
TRIM28	1	UHRF1	3	affinity chromatography technology, affinity chromatography technology	Quenneville S (2011), Quenneville S (2011)	2
ZFP57	1	DNMT3B	3	affinity chromatography technology	Quenneville S (2011)	1
DDB1	6	SUV39H1	0	affinity chromatography technology, pull down	Yang Y (2015), Yang Y (2015)	2
TRIM25	5	DNMT3A	17	affinity chromatography technology	Choudhury NR (2017)	1
UHRF1	3	RB1	2	affinity chromatography technology, affinity chromatography technology	Jeanblanc M (2005), Jeanblanc M (2005)	2
DNMT3A	17	F8A1	0	enzymatic study	Shikauchi Y (2009)	1
HIST1H3E	0	CBX5	3	affinity chromatography technology	Campos EI (2015)	1
DNMT3L	2	DNMT3A	17	affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Hata K (2002), Ooi SK (2007), Margot JB (2003), Chen ZX (2005), Chen ZX (2005), Suetake I (2004), Suetake I (2004), Suetake I (2004), Pacaud R (2014)	9
DAXX	5	CBX5	3	affinity chromatography technology	Hein MY (2015)	1
NRIP1	4	DNMT3A	17	affinity chromatography technology, pull down, imaging technique	Kiskinis E (2007), Kiskinis E (2007), Kiskinis E (2007)	3
TRIM28	1	SETDB1	3	two hybrid, affinity chromatography technology, affinity chromatography technology	Schultz DC (2002), Schultz DC (2002), Ivanov AV (2007)	3
PAF1	6	5430	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology, biochemical	Moniaux N (2006), Kim J (2010), Kim J (2010), Kim K (2013), Wu L (2014)	5
DNMT3A	17	PIAS1	4	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Ling Y (2004), Ling Y (2004), Ling Y (2004), Ling Y (2004), Liu B (2010), Liu B (2010)	6
MYC	2	PIAS2	2	affinity chromatography technology	Zhang Y (2007)	1
EHMT2	4	CBX5	3	pull down, imaging technique, affinity chromatography technology, affinity chromatography technology	Chin HG (2007), Chin HG (2007), Nozawa RS (2010), Roopra A (2004)	4
EED	1	TRIM28	1	affinity chromatography technology	Cao Q (2014)	1
DNMT3A	17	HIST1H3A	3	pull down, bioid, unspecified method, pull down	Otani J (2009), Lambert JP (2015), Sankaran SM (2016), Sankaran SM (2016)	4
MYC	2	5430	0	affinity chromatography technology	Koch HB (2007)	1
PIAS1	4	DNMT3B	3	affinity chromatography technology, imaging technique	Liu B (2010), Liu B (2010)	2
MPHOSPH8	1	HIST1H3A	3	unspecified method	Sun L (2015)	1
CUL4B	8	SUV39H1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015)	5
DNMT3A	17	LEO1	3	affinity chromatography technology	Rigbolt KT (2011)	1
CUL4B	8	PRMT5	3	affinity chromatography technology, affinity chromatography technology	Yang Y (2015), Yang Y (2015)	2
NRIP1	4	DNMT1	5	affinity chromatography technology, pull down, imaging technique	Kiskinis E (2007), Kiskinis E (2007), Kiskinis E (2007)	3
DAXX	5	DNMT3A	17	affinity chromatography technology	Halder UC (2013)	1
DNMT3A	17	IRF9	0	affinity chromatography technology	Hervouet E (2009)	1
EED	1	DDB1	6	affinity chromatography technology	Higa LA (2006)	1
DAXX	5	DNMT1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Muromoto R (2004), Muromoto R (2004), Halder UC (2013), Halder UC (2013), Zhang H (2013), Zhang H (2013)	6
ZFP57	1	TRIM28	1	affinity chromatography technology	Quenneville S (2011)	1
EHMT1	18	MPHOSPH8	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chang Y (2011), Chang Y (2011), Chang Y (2011), Hein MY (2015)	4
TRIM25	5	USP7	14	affinity chromatography technology	Choudhury NR (2017)	1
MYC	2	CTR9	10	affinity chromatography technology, affinity chromatography technology	Jaenicke LA (2016), Jaenicke LA (2016)	2
MYC	2	TRIM28	1	affinity chromatography technology	Koch HB (2007)	1
DNMT1	5	RB1	2	biochemical, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Robertson KD (2000), Robertson KD (2000), Robertson KD (2000), Pradhan S (2002), Pradhan S (2002)	5
EED	1	DNMT1	5	affinity chromatography technology, imaging technique, affinity chromatography technology	Vire E (2006), Vire E (2006), OHagan HM (2011)	3
EHMT2	4	TRIM28	1	affinity chromatography technology	Hauri S (2016)	1
HIST1H3A	3	EHMT1	18	x-ray crystallography, enzymatic study	Wu H (2010), Huang J (2010)	2
HDAC1	4	MYC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Matsuoka Y (2008), Matsuoka Y (2008), Liu T (2007), Liu T (2007), Liu T (2007), Koch HB (2007), Hwang IY (2012), Hein MY (2015)	8
PRMT5	3	DNMT3A	17	pull down	Zhao Q (2009)	1
UHRF2	1	RB1	2	far western blotting, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Mori T (2011), Mori T (2011), Mori T (2011), Mori T (2011), Lai M (2016)	5
DNMT3A	17	CBX4	1	pull down, affinity chromatography technology, affinity chromatography technology	Li B (2007), Li B (2007), Li B (2007)	3
USP7	14	SUV39H1	0	affinity chromatography technology, affinity chromatography technology	Mungamuri SK (2016), Mungamuri SK (2016)	2
RB1	2	MYC	2	two hybrid, fluorescent resonance energy transfe	Adnane J (1995), Ivanov AA (2017)	2
CDC73	1	5430	0	affinity chromatography technology	Rozenblatt-Rosen O (2005)	1
HIST1H3A	3	PAF1	6	affinity chromatography technology, pull down	Wu J (2012), Wu J (2012)	2
DNMT3B	3	CTR9	10	affinity chromatography technology	Rigbolt KT (2011)	1
EED	1	DNMT3A	17	affinity chromatography technology, imaging technique	Vire E (2006), Vire E (2006)	2
RBX1	2	SUV39H1	0	affinity chromatography technology	Yang Y (2015)	1
DNMT3A	17	HIC1	1	affinity chromatography technology, affinity chromatography technology	Zeng S (2016), Zeng S (2016)	2
LEO1	3	POLR2C	0	affinity chromatography technology	Hein MY (2015)	1
EZH2	4	EED	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, pull down, pull down, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	van Lohuizen M (1998), van Lohuizen M (1998), van Lohuizen M (1998), van der Vlag J (1999), van der Vlag J (1999), van der Vlag J (1999), Denisenko O (1998), Denisenko O (1998), Denisenko O (1998), Denisenko O (1998), Pasini D (2004), Cao R (2004), Su IH (2005), Hansen KH (2008), Margueron R (2008), Margueron R (2008), Shen X (2008), Shen X (2008), Hernandez-Munoz I (2005), Sarma K (2008), Sarma K (2008), Han Z (2007), Avdic V (2011), Kaneko S (2010), Kaneko S (2010), Yap DB (2011), Satijn DP (2001), Satijn DP (2001), Sewalt RG (1998), Sewalt RG (1998), Sewalt RG (1998), Sewalt RG (1998), Wang L (2013), Wu L (2013), Pasini D (2010), Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014), Wan C (2015), Hein MY (2015), Hein MY (2015), Chan YS (2013), Zhang H (2016), Zhang H (2016), Wang X (2017), Hauri S (2016), Hauri S (2016)	49
UBE2I	0	DAXX	5	two hybrid, enzymatic study, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, two hybrid	Ryu SW (2000), Knipscheer P (2008), Hsieh YL (2013), Hsieh YL (2013), Hsieh YL (2013), Chang CC (2011), Lin DY (2006), Lin DY (2006)	8
UBE2I	0	SETDB1	3	two hybrid	Bandyopadhyay S (2010)	1
DNMT1	5	HIC1	1	affinity chromatography technology, affinity chromatography technology	Zeng S (2016), Zeng S (2016)	2
DNMT1	5	CBX1	0	pull down	Fuks F (2003)	1
EZH2	4	SUV39H1	0	affinity chromatography technology, two hybrid	Weimann M (2013), Weimann M (2013)	2
UHRF1	3	EZH2	4	affinity chromatography technology, affinity chromatography technology	Babbio F (2012), Babbio F (2012)	2
TERF2IP	1	SP100	4	two hybrid	Lee OH (2011)	1
USP7	14	EZH2	4	pull down	de Bie P (2010)	1
SUV39H1	0	EHMT2	4	affinity chromatography technology	Huttlin EL (2017)	1
SPI1	1	DNMT3B	3	affinity chromatography technology, pull down	Suzuki M (2006), Suzuki M (2006)	2
DDB1	6	DNMT1	5	pull down	Yang Y (2015)	1
TRIM25	5	TRIM28	1	affinity chromatography technology	Choudhury NR (2017)	1
SUV39H1	0	CBX1	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Aagaard L (1999), Aagaard L (1999), Aagaard L (1999), Hauri S (2016)	4
EHMT1	18	DNMT3A	17	unspecified method, enzymatic study	Chang Y (2011), Chang Y (2011)	2
SUV39H1	0	HDAC1	4	affinity chromatography technology, pull down	Vaute O (2002), Vaute O (2002)	2
DNMT3A	17	USP7	14	pull down	Felle M (2011)	1
EED	1	HDAC1	4	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	van der Vlag J (1999), van der Vlag J (1999), van der Vlag J (1999), Hein MY (2015)	4
DNMT1	5	CBX5	3	affinity chromatography technology, affinity chromatography technology	Lehnertz B (2003), Smallwood A (2007)	2
UBE2I	0	PIAS2	2	two hybrid, two hybrid, two hybrid, pull down, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down	Rual JF (2005), Lee BH (2003), Bandyopadhyay S (2010), Schmidt D (2002), Wang J (2011), Rolland T (2014), Saul VV (2014), van den Akker E (2005), Schmidt D (2002)	9
UHRF1	3	SUV39H1	0	affinity chromatography technology, affinity chromatography technology	Babbio F (2012), Babbio F (2012)	2
HIST1H3E	0	DNMT1	5	affinity chromatography technology	Campos EI (2015)	1
DNMT3A	17	PIAS2	2	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Ling Y (2004), Ling Y (2004), Ling Y (2004), Ling Y (2004)	4
EED	1	DNMT3B	3	affinity chromatography technology, imaging technique, affinity chromatography technology	Vire E (2006), Vire E (2006), OHagan HM (2011)	3
CBX5	3	SUV39H1	0	two hybrid, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Fujita N (2003), Rual JF (2005), Nozawa RS (2010), Rolland T (2014), Huttlin EL (2017), Hauri S (2016)	6
DNMT1	5	HDAC1	4	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Robertson KD (2000), Achour M (2008), Achour M (2008), Kimura H (2003), Zhang Q (2005), Myant K (2008), Schnekenburger M (2007), Kang KA (2012), Cui S (2011), Cui S (2011), Hervouet E (2010), Cai Y (2014), Cai Y (2014), Yuan K (2016), Yuan K (2016)	15
CDC73	1	CTR9	10	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rozenblatt-Rosen O (2005), Rozenblatt-Rosen O (2005), Nordick K (2008), Nordick K (2008), Rozenblatt-Rosen O (2009), Kim J (2010), Mak AB (2010), Mak AB (2010), Ouna BA (2012), Takahashi A (2011), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	17
DDB1	6	DNMT3B	3	pull down	Yang Y (2015)	1
UBE2I	0	TRIM28	1	affinity chromatography technology, pull down, enzymatic study, pull down	Liang Q (2011), Garvin AJ (2013), Ivanov AV (2007), Neo SH (2015)	4
EZH2	4	TRIM28	1	affinity chromatography technology	Cao Q (2014)	1
TRIM25	5	HIC1	1	affinity chromatography technology	Choudhury NR (2017)	1
DNMT3L	2	HDAC1	4	pull down, pull down, pull down, pull down, affinity chromatography technology	Aapola U (2002), Aapola U (2002), Deplus R (2002), Deplus R (2002), Deplus R (2002)	5
EZH2	4	RBX1	2	affinity chromatography technology	Hein MY (2015)	1
RB1	2	CBX1	0	pull down	Fuks F (2003)	1
CDC73	1	DNMT3A	17	affinity chromatography technology, affinity chromatography technology	Rigbolt KT (2011), Rigbolt KT (2011)	2
PAF1	6	CTR9	10	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Nordick K (2008), Nordick K (2008), Nordick K (2008), Kim J (2010), Kim J (2010), Mak AB (2010), Mak AB (2010), Takahashi A (2011), Havugimana PC (2012), Wan C (2015), Hein MY (2015)	11
ZBTB18	9	DNMT3A	17	pull down, pull down, affinity chromatography technology, pull down	Fuks F (2001), Fuks F (2001), Fuks F (2001), Brenner C (2005)	4
EED	1	TFAP2A	1	affinity chromatography technology	Hein MY (2015)	1
CUL4B	8	USP7	14	affinity chromatography technology	Bennett EJ (2010)	1
DNMT3A	17	TFAP2A	1	affinity chromatography technology	Hervouet E (2009)	1
DNMT3A	17	CTR9	10	affinity chromatography technology	Rigbolt KT (2011)	1
TRIM25	5	DDB1	6	affinity chromatography technology	Choudhury NR (2017)	1
CBX5	3	HIST1H3A	3	affinity chromatography technology, pull down, pull down, unspecified method, imaging technique, bioid, affinity chromatography technology	Terada Y (2006), Lavigne M (2009), Lavigne M (2009), Dawson MA (2009), Dawson MA (2009), Lambert JP (2015), Huttlin EL (2017)	7
HIST1H3E	0	HDAC1	4	affinity chromatography technology	Campos EI (2015)	1
DNMT3B	3	POLR2H	0	affinity chromatography technology	Rigbolt KT (2011)	1
PRMT5	3	DNMT1	5	genetic interference	Wong AS (2016)	1
EHMT2	4	UHRF1	3	imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin W (2010), Kim JK (2009), Kim JK (2009), Zhang J (2011)	4
USP7	14	EED	1	pull down, affinity chromatography technology	de Bie P (2010), Cao Q (2014)	2
8339	0	CBX4	1	bioid	Lambert JP (2015)	1
UBE2I	0	HIC1	1	enzymatic study, affinity chromatography technology	Stankovic-Valentin N (2007), Dehennaut V (2013)	2
CBX5	3	SETDB1	3	affinity chromatography technology	Loyola A (2009)	1
MYC	2	DDB1	6	affinity chromatography technology	Choi SH (2010)	1
DNMT3B	3	5430	0	affinity chromatography technology	Rigbolt KT (2011)	1
CUL4B	8	DNMT1	5	affinity chromatography technology, affinity chromatography technology, pull down	Yang Y (2015), Yang Y (2015), Yang Y (2015)	3
SETDB1	3	DNMT3B	3	affinity chromatography technology	Li H (2006)	1
RB1	2	SPI1	1	pull down	Hagemeier C (1993)	1
SETDB1	3	HIST1H3A	3	enzymatic study, pull down	Vandel L (2001), Binda O (2011)	2
HIST1H3A	3	HDAC1	4	affinity chromatography technology, pull down, affinity chromatography technology	Nishioka K (2002), Li X (2014), Hein MY (2015)	3
PRMT5	3	HDAC1	4	genetic interference	Wong AS (2016)	1
DNMT3A	17	RB1	2	pull down	Fuks F (2001)	1
SPI1	1	DNMT3A	17	affinity chromatography technology, pull down	Suzuki M (2006), Suzuki M (2006)	2
TRIM28	1	HIST1H3A	3	imaging technique	Li X (2010)	1
UBE2I	0	PIAS1	4	two hybrid, pull down, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down	Lee BH (2003), Sapetschnig A (2002), Kahyo T (2001), Bandyopadhyay S (2010), Driscoll JJ (2010), Kahyo T (2001), Yin Y (2012), Gocke CB (2005), van den Akker E (2005), Ogawa H (2009), Schmidt D (2002), Gibbs-Seymour I (2015)	12
DNMT3A	17	UBE2I	0	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Ling Y (2004), Ling Y (2004), Ling Y (2004), Ling Y (2004)	4
EHMT2	4	DNMT1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Esteve PO (2006), Esteve PO (2006), Cai Y (2014)	3
UHRF1	3	DNMT3A	17	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Meilinger D (2009), Meilinger D (2009), Felle M (2011), Zhang J (2011)	4
UHRF1	3	HIST1H3A	3	unspecified method, enzymatic study, bioid	Zhang J (2011), Karagianni P (2008), Lambert JP (2015)	3
MYC	2	SUV39H1	0	genetic interference, affinity chromatography technology	Toyoshima M (2012), Hauri S (2016)	2