Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications
ABCA1	19	CERIVASTATIN	CHEMBL1477		PharmGKB
ABCA1	19	PROBUCOL	CHEMBL608	inhibitor	GuideToPharmacologyInteractions, ChemblInteractions, DrugBank	19427182, 19075491, 19458386, 20075420, 1868500, 15514211
ABCA1	19	CYCLOSPORINE	CHEMBL160		NCI	15084924
ABCA1	19	DORZOLAMIDE	CHEMBL218490		GuideToPharmacologyInteractions
ABCA1	19	ADENOSINE TRIPHOSPHATE	CHEMBL14249		DrugBank	17224860, 17135600, 16858612
ABCA1	19	GLYBURIDE	CHEMBL472	inhibitor	DrugBank	15905177, 14660039, 19805629, 12426219, 15039140, 15102890

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
ABCA1	rs12003906	C	atorvastatin	efficacy	yes	As measured by reduction in LDLc. Association was seen at low and high doses. Association reported for minor allele but base not specified; estimated from dbSNP to be the C allele (on the plus chromosomal strand).	Allele C is associated with decreased response to atorvastatin, pravastatin or simvastatin in people with Hyperlipidemias as compared to allele G.	20031551	827807823
ABCA1	rs2230808	CC	fenofibrate	efficacy	yes	Patients with the CC genotype had a greater small high-density lipoprotein (HDL) particle concentration (units = umol/L) and a greater total HDL particle concentration after fenofibrate treatment for 3 weeks, as compared to patients with the TT genotype.	Genotype CC is associated with increased response to fenofibrate in people with Hypertriglyceridemia as compared to genotype TT.	20346718	982044801
ABCA1	rs2230806	CT	fenofibrate	efficacy	yes	Patients with the CT genotype had a greater small high-density lipoprotein (HDL) particle concentration (units = umol/L) after fenofibrate treatment for 3 weeks, as compared to patients with the CC genotype.	Genotype CT is associated with increased response to fenofibrate in people with Hypertriglyceridemia as compared to genotype CC.	20346718	982044812
ABCA1	rs2230806	TT	fenofibrate	efficacy	yes	Patients with the TT genotype had a greater total high-density lipoprotein (HDL) particle concentration (units = umol/L) after fenofibrate treatment for 3 weeks, as compared to patients with the CC genotype.	Genotype TT is associated with increased response to fenofibrate in people with Hypertriglyceridemia as compared to genotype CC.	20346718	982044822
ABCA1	rs2487032	A	clopidogrel	metabolism/PK	yes	This variant was associated increased the concentration of plasma clopidogrel’s active metabolite H4 and increased inhibition of platelet function. However, it was not associated with clinical outcome of clopidogrel.	Allele A is associated with increased metabolism of clopidogrel as compared to genotype GG.	27981573	1448624896