PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
ITGAV	7	PTK2	2	affinity chromatography technology, affinity chromatography technology	Lee DY (2010), Avraham HK (2003)	2
SHC1	0	HSP90AA1	7	affinity chromatography technology	Brehme M (2009)	1
CD44	1	SRC	2	affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Bourguignon LY (2001), Bourguignon LY (2001), Su YJ (2011), Zhu D (1998)	4
CBL	7	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tanaka Y (2008), Tanaka Y (2008), Hoff H (2007), Chernock RD (2001), Chernock RD (2001)	5
CTNNB1	30	EZR	8	affinity chromatography technology	Hiscox S (1999)	1
GRB2	2	HSP90AA1	7	affinity chromatography technology	Brehme M (2009)	1
IL6ST	0	PTPN6	0	affinity chromatography technology	Bartoe JL (2000)	1
CD44	1	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsatas D (2002), Wakahara K (2005), Wakahara K (2005), Perez A (2013)	4
ERBB2	6	PTPN11	20	affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Jones RB (2006), Yao Z (2017), Vogel W (1996)	5
TGFBR2	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Krymskaya VP (1997), Huttlin EL (2015), Huttlin EL (2017)	3
ERBIN	5	CBL	7	affinity chromatography technology	Yao S (2015)	1
SRC	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Burnham MR (1999), Song JJ (2010), Liu W (2010), Chen TC (2014)	4
CTNNB1	30	SRC	2	affinity chromatography technology	Xi Y (2013)	1
ERBB3	3	PIK3R2	3	affinity chromatography technology, unspecified method, affinity chromatography technology	Schulze WX (2006), Jones RB (2006), Li J (2013)	3
IL6ST	0	STAT3	0	affinity chromatography technology	Novotny-Diermayr V (2002)	1
ERBB3	3	PTK6	1	affinity chromatography technology, unspecified method	Kamalati T (2000), Jones RB (2006)	2
HSP90AA1	7	PTK2B	6	affinity chromatography technology	Taipale M (2012)	1
ERBIN	5	PICK1	2	two hybrid	Jaulin-Bastard F (2001)	1
CBL	7	PIK3R2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Lin H (2001), Hartley D (1995), Feshchenko EA (2004), Alcazar I (2009), Brehme M (2009), Brehme M (2009), Grossmann A (2015)	7
PTGER3	2	ERBB2	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ERBB2	6	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Scaltriti M (2009), Graus-Porta D (1997), Le XF (2005), Chen TC (2014), Ritch PS (2005)	5
CBL	7	HSPA4	3	affinity chromatography technology	Valiya Veettil M (2011)	1
HSP90AA1	7	ERBB2	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xu W (2001), Jeong JH (2008), Mollapour M (2010), Citri A (2002), Jung Y (2007), Suzuki T (2011), Tsutsumi S (2012), Taipale M (2012), Bali P (2005), Woodford MR (2016), Yan YY (2011), Yan YY (2011)	12
ERBB2	6	STAT3	0	affinity chromatography technology, unspecified method	Ren Z (2002), Jones RB (2006)	2
ERBB3	3	PTPRR	3	two hybrid	Yao Z (2017)	1
ITGAV	7	CBL	7	affinity chromatography technology	Elsegood CL (2006)	1
MUC1	0	EGFR	5	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique, two hybrid, protein complementation assay, affinity chromatography technology, enzymatic study	Schroeder JA (2001), Li Y (2001), Li Y (2001), Pochampalli MR (2007), Merlin J (2011), Merlin J (2011), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Schroeder JA (2001)	10
CD44	1	EZR	8	pull down	Legg JW (2002)	1
PTPN6	0	PLCG2	11	affinity chromatography technology, fluorescent resonance energy transfe	Matalon O (2016), Matalon O (2016)	2
PIK3R2	3	SHC1	0	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009)	2
HSP90AA1	7	CDK4	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsutsumi S (2012), Wang H (2002), Taipale M (2012), Varjosalo M (2013), Huttlin EL (2015), Woodford MR (2016), Huttlin EL (2017)	7
SHC1	0	IL6ST	0	affinity chromatography technology, pull down	Giordano V (1997), Giordano V (1997)	2
SRC	2	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Olayioye MA (1999), Keely SJ (2000), Sato K (2000), Lee CW (2007), Jaganathan S (2011), Jaganathan S (2011), Lee IT (2010), Hitosugi T (2007), Chang CC (2012), Chang CC (2012), Tung WH (2011), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Yao Z (2017)	15
EGFR	5	PTPN6	0	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid	Tomic S (1995), Keilhack H (1998), Keilhack H (1998), Yao Z (2017)	4
EGFR	5	EZR	8	protein complementation assay	Petschnigg J (2014)	1
XPO1	8	ERRFI1	1	affinity chromatography technology	Kirli K (2015)	1
CTNNB1	30	TGFBR2	0	affinity chromatography technology	Tian YC (2002)	1
ERBB2	6	H2AFY	1	affinity chromatography technology, affinity chromatography technology	Li X (2012), Li X (2012)	2
GRB2	2	PIK3R1	6	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Saleem A (1995), Saleem A (1995), Wang J (1995), Wang J (1995), Wang J (1995), Bandyopadhyay S (2010), Takahashi Y (1999), Gelkop S (2001), Jain SK (1997), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Cerboni C (1998), Bisson N (2011), Bisson N (2011), Weinger JG (2008), Weinger JG (2008), Weinger JG (2008)	18
ERRFI1	1	ACTB	8	affinity chromatography technology	Li J (2013)	1
STUB1	4	SRC	2	pull down, affinity chromatography technology, imaging technique, enzymatic study	Yang M (2011), Yang M (2011), Yang M (2011), Yang M (2011)	4
HSP90AA1	7	STAT3	0	affinity chromatography technology	Sato N (2003)	1
EGFR	5	HSPA4	3	protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Deribe YL (2009), Deribe YL (2009), Citri A (2002), Tong J (2008), Kotlyar M (2015), Petschnigg J (2014)	6
ERBB3	3	SHC1	0	affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Jones RB (2006), Li J (2013), Hellyer NJ (2001)	5
ERBB2	6	CDH2	4	affinity chromatography technology, affinity chromatography technology	Rappl A (2008), Rappl A (2008)	2
ERBB2	6	PICK1	2	two hybrid, affinity chromatography technology	Jaulin-Bastard F (2001), Jaulin-Bastard F (2001)	2
TGFBR2	0	ERBB2	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HSP90AA1	7	PTK2	2	affinity chromatography technology	Taipale M (2012)	1
NAALADL2	0	ERBB2	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PTK2B	6	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Haglund K (2004), Haglund K (2004), Sanjay A (2001), Schmidt MH (2003)	4
EGFR	5	PIK3R2	3	affinity chromatography technology, unspecified method, affinity chromatography technology, two hybrid, pull down, protein complementation assay	Tong J (2009), Jones RB (2006), Foerster S (2013), Kotlyar M (2015), Gout I (1992), Petschnigg J (2014)	6
STAT3	0	CBL	7	two hybrid	Grossmann A (2015)	1
PTPN6	0	PIK3R1	6	two hybrid	Sathish JG (2001)	1
EGFR	5	KPNB1	3	affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Tong J (2014)	2
ERBB3	3	PTK2B	6	affinity chromatography technology	Verma N (2017)	1
EGFR	5	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ettenberg SA (1999), Tvorogov D (2002), Pennock S (2008), Umebayashi K (2008), Ng C (2008), Ng C (2008), Povlsen GK (2008), Khan EM (2008), Su X (2007), Shtiegman K (2007), Han W (2006), Visser GD (2005), Tsacoumangos A (2005), Prasad NK (2005), Gur G (2004), Kowanetz K (2004), Feshchenko EA (2004), Wu WJ (2003), Schmidt MH (2003), Bao J (2003), Rubin C (2003), Waterman H (1999), Bonaccorsi L (2007), Dey N (2011), Miraoui H (2010), Guo HB (2009), Tong J (2009), Tong J (2009), Sun Q (2010), Sanada F (2009), Rafiq K (2011), Ravid T (2004), Ravid T (2004), Duan L (2011), Duan L (2011), Haglund K (2005), Oksvold MP (2003), Oksvold MP (2003), Gui A (2012), Yang S (2006), de Melker AA (2004), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Raguz J (2007), de Melker AA (2004), Thien CB (2001), Kassenbrock CK (2004), Tarcic G (2009), Schroeder B (2012), Adachi S (2009), Shen F (2007), Mitsushima M (2006), Choi JH (2003), Burke P (2001), Tanaka S (1995), Meisner H (1995), Meisner H (1995), Kumar EA (2012), Tong J (2008), Dou H (2012), Levkowitz G (1999), Levkowitz G (1999), Bode AM (2009), Thomas C (2012), Meijer IM (2013), Chang CC (2012), Chang CC (2012), Smith CJ (2013), Gan Y (2010), Scott RP (2005), Fukazawa T (1996), Fukazawa T (1996), Fukazawa T (1996), Wang L (2013), Hong SY (2013), Sigismund S (2013), Sigismund S (2013), Sigismund S (2013), Meisner H (1997), Odintsova E (2013), Kondratov KA (2010), He Z (2014), Tong J (2014), Balaji K (2012), Kiuchi T (2014), Zhang B (2005), Waterman H (1999), Ha Thi HT (2015), Yao S (2015), Kortuem F (2015), Igloi Z (2015), Song F (2016), Song F (2016), Lin TY (2017), Conte A (2017)	96
CBL	7	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jain SK (1997), Liu SK (1998), Ettenberg SA (1999), Wong A (2002), Wong A (2002), Robertson H (1997), Donovan JA (1994), Park RK (1999), Erdreich-Epstein A (1999), Gesbert F (1998), Gesbert F (1998), Gesbert F (1998), Husson H (1997), Saci A (2002), Odai H (1997), Ng C (2008), Khan EM (2008), Bandyopadhyay S (2010), Jiang X (2003), Waterman H (2002), Miraoui H (2010), Ravid T (2004), Ingham RJ (1996), Erdreich-Epstein A (1997), Rellahan BL (2003), Izadi KD (1998), Wang Y (1999), Chu J (1998), Bonita DP (1997), Boussiotis VA (1997), Meisner H (1995), Meisner H (1995), Barber DL (1997), Shishido T (2000), Bartkiewicz M (1999), Buday L (1996), Tarcic G (2009), Belleudi F (2007), Brizzi MF (1996), Brenner B (2001), Donovan JA (1996), Donovan JA (1996), Donovan JA (1996), Gaston I (2004), Gaston I (2004), Tsygankov AY (1996), Tsygankov AY (1996), Hunter S (1997), Jain SK (1997), Levkowitz G (1996), Liu YC (1997), Odai H (1995), Odai H (1995), Meisner H (1995), Huang JY (2000), Panchamoorthy G (1996), Panchamoorthy G (1996), Yokouchi M (1997), Oda A (1996), Fukazawa T (1995), Fukazawa T (1995), Selbach M (2006), Brehme M (2009), Brehme M (2009), Fukazawa T (1995), Cerboni C (1998), Cerboni C (1998), Fixman ED (1997), Anderson SM (1997), Houtman JC (2006), Brizzi MF (1996), Scott RP (2005), Scott RP (2005), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Umehara H (2002), Taipale M (2014), Taipale M (2014), Grossmann A (2015), Grossmann A (2015), Igloi Z (2015), Huttlin EL (2017)	83
HSP90AA1	7	XPO1	8	affinity chromatography technology	Falsone SF (2005)	1
MUC1	0	ERBB2	6	affinity chromatography technology, imaging technique, affinity chromatography technology	Li Y (2003), Li Y (2003), Schroeder JA (2001)	3
EGFR	5	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, imaging technique	Tong J (2009), Wen G (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Chen TC (2014)	6
MUC1	0	JUP	7	affinity chromatography technology, imaging technique	Li Y (2003), Li Y (2003)	2
TGFBR2	0	CBL	7	pull down, affinity chromatography technology, enzymatic study	Zuo W (2013), Zuo W (2013), Zuo W (2013)	3
PLCG2	11	PLCG1	6	imaging technique	Chen TC (2014)	1
PIK3R2	3	PTPN11	20	affinity chromatography technology	Brehme M (2009)	1
XPO1	8	STAT1	1	unspecified method, affinity chromatography technology	Xu D (2012), Kirli K (2015)	2
CBL	7	PLCG1	6	far western blotting, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique	Tvorogov D (2002), Tvorogov D (2002), Tvorogov D (2002), Graham LJ (1998), Singh AJ (2007), Rellahan BL (2003), Rellahan BL (2003), Okabe S (2006), Choi JH (2003), Choi JH (2003), Braiman A (2006), Braiman A (2006), Braiman A (2006), Chen TC (2014)	14
PTK2B	6	GRB2	2	affinity chromatography technology, affinity chromatography technology	Blaukat A (1999), Bruzzaniti A (2009)	2
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
PTPN11	20	STAT1	1	two hybrid	Daakour S (2016)	1
EGFR	5	ACTB	8	affinity chromatography technology	Chiu HC (2012)	1
PLCG1	6	PTPN6	0	affinity chromatography technology, affinity chromatography technology	Matalon O (2016), Matalon O (2016)	2
HSP90AA1	7	HSPA4	3	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Kim TS (2006), Hidalgo-de-Quintana J (2008), Skarra DV (2011), Wan C (2015)	4
PLCG1	6	ERBB2	6	affinity chromatography technology, biochemical, unspecified method	Peles E (1991), Arteaga CL (1991), Jones RB (2006)	3
CD44	1	STAT3	0	affinity chromatography technology	Su YJ (2011)	1
ERBB2	6	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, far western blotting	Schroeder JA (2002), Bonvini P (2001), Schroeder JA (2002), Schroeder JA (2002), Kanai Y (1995), Kanai Y (1995)	6
EGFR	5	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Citri A (2002), Yang S (2006), Shimamura T (2005), Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014)	8
STAT3	0	PIK3R1	6	two hybrid	Grossmann A (2015)	1
SHC1	0	ACTB	8	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
EGFR	5	ERRFI1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tong J (2009), Pao-Chun L (2009), Tong J (2008), Foerster S (2013), Li J (2013), Tong J (2014), Li J (2013), Park E (2015), Park E (2015), Park E (2015), Park E (2015), Yao Z (2017)	12
GRB7	1	ERBB3	3	affinity chromatography technology, unspecified method, affinity chromatography technology	Fiddes RJ (1998), Jones RB (2006), Li J (2013)	3
CTNNB1	30	JUP	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Hazan RB (1998), Kucerova D (2001), Hein MY (2015), Chen TC (2014)	4
CDH2	4	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Straub BK (2003), Wahl JK (2003), Fischer L (2002), Sadot E (2002), Chung FZ (2014), Boscher C (2008)	6
PTK2	2	STAT3	0	affinity chromatography technology, imaging technique	Ryu H (2000), Chen TC (2014)	2
MUC1	0	GRB2	2	pull down, affinity chromatography technology, two hybrid	Pandey P (1995), Pandey P (1995), Bandyopadhyay S (2010)	3
SRC	2	PTK2B	6	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Keely SJ (2000), Kumar S (1999), Dikic I (1996), Dikic I (1996), Bruzzaniti A (2009)	5
PTPN11	20	CTNNB1	30	affinity chromatography technology	Ukropec JA (2000)	1
IL6ST	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Lehmann U (2003), Anhuf D (2000), Kim H (1997), Schmitz J (2000)	4
EZR	8	HSPA4	3	biochemical	Wan C (2015)	1
GRB2	2	ACTB	8	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
PIK3R1	6	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang S (1999), Takahashi Y (1999), Craddock BL (1997), Wu CJ (2000), Wu CJ (2001), Yu WM (2006)	6
EGFR	5	CDH2	4	affinity chromatography technology, affinity chromatography technology	Rappl A (2008), Rappl A (2008)	2
SRC	2	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olayioye MA (1999), Cirri P (1997), Chang YJ (2004), Chang YJ (2004)	4
GRB2	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Bennett AM (1994), Ward AC (1998), Yin T (1997), Tang J (1997), Tang H (1999), Hadari YR (1998), Zhang S (1999), Wong L (1996), Brehme M (2009), Craddock BL (1997), Bisson N (2011), Blagoev B (2003), Bisson N (2011), Tauchi T (1995), Huttlin EL (2017), Kapoor GS (2010), Kapoor GS (2010), Vogel W (1996), Vogel W (1996), Yu WM (2006)	21
ERBB2	6	PTPN6	0	two hybrid, affinity chromatography technology	Yao Z (2017), Yao Z (2017)	2
EGFR	5	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Schulze WX (2006), Sakaguchi K (1998), Tong J (2009), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Burke P (2001), Katayama H (1999), Tong J (2008), Zhang L (1999), Levkowitz G (1999), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Foerster S (2013), Gotoh N (1994), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), Li J (2013), Prigent SA (1996), Prigent SA (1996), Grosse R (2000), Yao Z (2017), Wills MK (2014), Wills MK (2014), Kapoor GS (2010)	29
CDK4	2	CD44	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
XPO1	8	CTNNB1	30	affinity chromatography technology	Kirli K (2015)	1
EGFR	5	PTK2B	6	affinity chromatography technology, affinity chromatography technology	Keely SJ (2000), Ivankovic-Dikic I (2000)	2
ERBB2	6	ITGAV	7	affinity chromatography technology, affinity chromatography technology	Lal S (2015), Lal S (2015)	2
GRB2	2	PTPN6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Kon-Kozlowski M (1996), Saci A (2002)	3
PLCG2	11	SHC1	0	affinity chromatography technology, affinity chromatography technology	Perskvist N (2000), Boudot C (2002)	2
CBL	7	PTPN6	0	affinity chromatography technology	Kant AM (2002)	1
IL6ST	0	ERBB2	6	affinity chromatography technology, affinity chromatography technology	Grant SL (2002), Grant SL (2002)	2
JUP	7	ERBB2	6	far western blotting, imaging technique	Kanai Y (1995), Chen TC (2014)	2
ERBB3	3	PTPN11	20	affinity chromatography technology, two hybrid	Crovello CS (1998), Yao Z (2017)	2
DLG4	11	PTK2B	6	affinity chromatography technology, pull down	Seabold GK (2003), Seabold GK (2003)	2
ERBIN	5	CTNNB1	30	unspecified method	Boisguerin P (2004)	1
PTK2	2	STAT1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Xie B (2001), Xie B (2001), Xie B (2001), Zhang L (2010), Zhang L (2010), Chen TC (2014)	6
PTK2	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Manes S (1999), Takahashi A (2011)	2
PLCG1	6	PTK2	2	affinity chromatography technology	Zhang X (1999)	1
GRB2	2	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Skolnik EY (1993), Skolnik EY (1993), Puil L (1994), Satoh T (1996), Fixman ED (1996), Fixman ED (1996), Fixman ED (1996), Ishihara H (1997), Fournier E (1999), Ravichandran KS (1994), Lamprecht R (2002), Park RK (1999), Sakaguchi K (2001), Park RK (1999), Park RK (1999), Hallak H (2001), Yokote K (1994), Saci A (2002), Zhang S (1999), Lazar DF (1994), VanderKuur J (1995), Kanai M (1997), Spivak-Kroizman T (1994), Giordano V (1997), Drobot L (2005), Erdreich-Epstein A (1997), Takahashi Y (1999), Barber DL (1997), Ahn SC (2003), Odai H (1995), Panchamoorthy G (1996), Panchamoorthy G (1996), Brehme M (2009), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Zhang L (1999), Brizzi MF (1996), Brizzi MF (1996), Liu BA (2012), Bisson N (2011), Fukazawa T (1996), Bisson N (2011), Umehara H (2002), Oksvold MP (2001), Oksvold MP (2001), Li J (2013), Li J (2013), Ueno H (1995), Prigent SA (1996), Wills MK (2014), Rausch O (1997), Ho JM (2002), Ho JM (2002), Yu WM (2006), Klint P (1995)	57
ERBB2	6	ERBB2	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Odintsova E (2003), Scaltriti M (2009), Lam PB (2008)	3
STUB1	4	HSP90AA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, enzymatic study, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, pull down	Zhang L (2007), Zhang M (2005), Tateishi Y (2004), Tateishi Y (2004), Connell P (2001), Ko HS (2009), Kumar P (2007), Kumar P (2007), Wang L (2011), Stankiewicz M (2010), Graf C (2010), Kundrat L (2010), Kundrat L (2010), Kundrat L (2010), Kundrat L (2010), Morishima Y (2008), Zhou P (2003), Zhang M (2008), Grelle G (2006), Kim SA (2005), Arndt V (2005), Muller P (2012), Burch L (2004), Burch L (2004), Jang KW (2011), Schuelke JP (2010), Wang Q (2012), Shimamoto S (2013), Shimamoto S (2013), Shimamoto S (2013), Gano JJ (2010), Skarra DV (2011), Yang SW (2013), Grelle G (2006), Grelle G (2006), Narayan V (2015)	36
SRC	2	ERRFI1	1	enzymatic study	Park E (2015)	1
ERBB2	6	HSPA4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Citri A (2002), Jung Y (2007), Suzuki T (2011)	3
ERBB2	6	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scaltriti M (2009), Shtiegman K (2007), Haslekas C (2005), Riedemann J (2007), Burke P (2001), Meijer IM (2011), Chen TC (2014), Li J (2013), Li J (2013), Caiazza F (2010), Caiazza F (2010), Sharif A (2009)	12
SRC	2	ERBB2	6	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Ren Z (2002), Li X (2007), Liang K (2010), Liang K (2010), Shen JP (2017)	5
ERRFI1	1	ERBB2	6	affinity chromatography technology, two hybrid	Li J (2013), Arroyo R (2015)	2
PTK2	2	SRC	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology	Hsia DA (2003), Hecker TP (2002), Angers-Loustau A (1999), Relou IA (2003), Messina S (2003), Lebrun P (1998), Ponnala S (2011), Grossmann A (2015), Chen TC (2014), Lee J (2013), Reiske HR (2000)	11
CBL	7	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kassenbrock CK (2002), Rafiq K (2011), Rellahan BL (2003), Vantler M (2006), Shishido T (2000), Shishido T (2000), Song JJ (2010), Sanjay A (2006), Sanjay A (2006), Tanaka S (1995), Tanaka S (1995), Tanaka S (1995), Szymkiewicz I (2004), Hashimoto S (2006)	14
PTPN6	0	PTK2B	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ganju RK (2000), Ganju RK (2000), Kumar S (1999), Kumar S (1999), Kumar S (1999)	5
MUC1	0	ERBB3	3	affinity chromatography technology	Schroeder JA (2001)	1
IL6ST	0	GRB2	2	pull down, affinity chromatography technology	Lee IS (1997), Lee IS (1997)	2
HSPA4	3	JUP	7	biochemical	Kristensen AR (2012)	1
STUB1	4	HSPA4	3	pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, pull down, pull down, enzymatic study, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ballinger CA (1999), Ballinger CA (1999), Ballinger CA (1999), Dai Q (2005), Tateishi Y (2004), Tateishi Y (2004), Ko HS (2009), Qian SB (2009), Kumar P (2007), Kumar P (2007), Wang L (2011), Wang L (2011), Wang L (2011), Graf C (2010), Kundrat L (2010), Matsumoto K (2011), Kundrat L (2010), Kundrat L (2010), Morishima Y (2008), Luo W (2010), Soss SE (2011), Zhou P (2003), Kalia LV (2011), Gao Y (2010), Gao Y (2010), Grelle G (2006), Rao SN (2010), Tetzlaff JE (2008), Kim SA (2005), Dai Q (2003), Zhang X (2011), Zhang X (2011), Muller P (2012), Jang KW (2011), Schuelke JP (2010), Jinwal UK (2012), Shimamoto S (2013), Shimamoto S (2013), Shimamoto S (2013), Mao RF (2013), Lee JS (2013), Lee JS (2013)	42
PTGER3	2	PIK3R1	6	affinity chromatography technology	Huttlin EL (2015)	1
CBL	7	ERBB2	6	pull down, affinity chromatography technology	Zhou P (2003), Bisaro B (2016)	2
HSP90AA1	7	PTK6	1	affinity chromatography technology	Taipale M (2012)	1
PTK2	2	ERBB2	6	imaging technique, affinity chromatography technology, affinity chromatography technology	Chen TC (2014), Ritch PA (2003), Ritch PA (2003)	3
ERBB2	6	KPNB1	3	affinity chromatography technology, affinity chromatography technology	Giri DK (2005), Giri DK (2005)	2
ERBB2	6	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method	Schulze WX (2006), Bourguignon LY (2001), Olayioye MA (1998), Li X (2007), Li X (2007), Crovello CS (1998), Jones RB (2006)	7
EGFR	5	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, affinity chromatography technology, enzymatic study	Schulze WX (2006), Tomic S (1995), Crovello CS (1998), Jones RB (2006), Yao Z (2017), Kapoor GS (2010), Vogel W (1996)	7
EGFR	5	JUP	7	pull down, affinity chromatography technology, two hybrid, protein complementation assay	Hazan RB (1998), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014)	4
EGFR	5	PTK6	1	affinity chromatography technology, unspecified method	Kamalati T (1996), Jones RB (2006)	2
PTK6	1	ERBB2	6	affinity chromatography technology, affinity chromatography technology	Xiang B (2008), Xiang B (2008)	2
CBL	7	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park RK (1999), Gesbert F (1998), Erdreich-Epstein A (1997), Wang Y (1999), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Brizzi MF (1996), Fukazawa T (1996)	9
GRB7	1	PTK2	2	pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down	Han DC (1999), Han DC (1999), Grossmann A (2015), Grossmann A (2015), Reiske HR (2000)	5
EGFR	5	GRAP2	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
PTPN6	0	PTK2	2	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
ERBB2	6	STUB1	4	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Xu W (2002), Jung Y (2007), Jung Y (2007), Zhou P (2003), Zhou P (2003), Li X (2007), Li X (2007), Xu W (2002), Bisaro B (2016)	9
EGFR	5	PLCG1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tvorogov D (2002), Bedrin MS (1997), Crovello CS (1998), Choi JH (2003), Jones RB (2006), Tong J (2014), Egan JE (2002), Wu D (2009), Wu D (2009)	9
PTGER3	2	PIK3R2	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PTPN11	20	PTK2B	6	affinity chromatography technology, affinity chromatography technology, far western blotting, enzymatic study	Chauhan D (2000), Chauhan D (2000), Chauhan D (2000), Chauhan D (2000)	4
EZR	8	PTK2	2	pull down	Poullet P (2001)	1
SRC	2	PTPN11	20	enzymatic study	Vogel W (1996)	1
CTNNB1	30	ACTB	8	affinity chromatography technology	Chang CC (2012)	1
GRB2	2	PTK2	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, two hybrid	Sieg DJ (2000), Angers-Loustau A (1999), Hildebrand JD (1996), Messina S (2003), Arold ST (2002), Vinayagam A (2011)	6
SHC1	0	PIK3R1	6	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harrison-Findik D (1995), Ren SY (2005), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Lee DY (2010)	6
XPO1	8	ERBIN	5	affinity chromatography technology	Kirli K (2015)	1
SHC1	0	PLCG1	6	affinity chromatography technology	Fixman ED (1996)	1
EGFR	5	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Yuan ZL (2004), Olayioye MA (1999), Lo HW (2005), Lo HW (2005), Crovello CS (1998), Jaganathan S (2011), Jaganathan S (2011), Andl CD (2004), Lo HW (2010), Foerster S (2013), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), de la Iglesia N (2008), Fan QW (2013), Fan QW (2013)	18
PTK2	2	EGFR	5	affinity chromatography technology, two hybrid, protein complementation assay	Sieg DJ (2000), Kotlyar M (2015), Petschnigg J (2014)	3
EGFR	5	PLCG2	11	unspecified method, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Petschnigg J (2014)	5
SHC1	0	PTK2	2	affinity chromatography technology	Hecker TP (2002)	1
GRAP2	0	ERBB2	6	unspecified method, imaging technique	Jones RB (2006), Chen TC (2014)	2
STAT3	0	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology	Gunaje JJ (2001), Spiekermann K (2001), Xia L (2002), Chen TC (2014), Li X (2015), Ghosh MK (2005), Huttlin EL (2017)	7
ERBB2	6	OPCML	1	affinity chromatography technology, affinity chromatography technology	McKie AB (2012), McKie AB (2012)	2
PTK2B	6	ERBB2	6	affinity chromatography technology, imaging technique	Zrihan-Licht S (2000), Chen TC (2014)	2
ERBB3	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Li J (2013)	3
EGFR	5	PTPRR	3	two hybrid	Yao Z (2017)	1
STAT3	0	PIK3R2	3	two hybrid	Grossmann A (2015)	1
IL6ST	0	PIK3R1	6	affinity chromatography technology	Chung TD (2000)	1
CBL	7	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Gesbert F (1998), Gesbert F (1998), Zhang S (1999), Dufour C (2008), Feshchenko EA (2004), Kassenbrock CK (2002), Fang D (2001), Valiya Veettil M (2011), Miao H (2002), Miao H (2002), Ueno H (1998), Gelkop S (2001), Wang Y (1999), Saci A (2000), Matsuo T (1996), Matsuo T (1996), Jackson JG (2000), Meisner H (1995), Saci A (1999), Saci A (1999), Beckwith M (1996), Beckwith M (1996), Song JJ (2010), Hartley D (1996), Finkelstein LD (2000), Ren SY (2005), Hunter S (1997), Hunter S (1997), Jain SK (1997), Jain SK (1997), Swaminathan G (2007), van Leeuwen JE (1999), Ren SY (2005), Ren SY (2005), Alcazar I (2009), Liu YC (1997), Matsuo T (1996), Matsuo T (1996), Lottin-Divoux S (2006), Kitanaka A (1996), Liu YC (1997), Grossmann AH (2004), Panchamoorthy G (1996), Panchamoorthy G (1996), Chernock RD (2001), Chernock RD (2001), Fukazawa T (1995), Fukazawa T (1995), Brehme M (2009), Hakak Y (2000), Hakak Y (2000), Fukazawa T (1995), Liu Y (1999), Cerboni C (1998), Cerboni C (1998), Momose H (2003), Fukazawa T (1996), Fukazawa T (1996), Bulut GB (2013), Bulut GB (2013), Grossmann A (2015)	61
PLCG1	6	SRC	2	affinity chromatography technology	Dhar A (1994)	1
GRB2	2	ERRFI1	1	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Bisson N (2011), Wang J (2011), Wang J (2011), Li J (2013), Li J (2013), Ying H (2010), Huttlin EL (2017)	8
ERBB2	6	POLR1B	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li LY (2011), Li LY (2011), Hein MY (2015)	3
ERBB3	3	ACTB	8	affinity chromatography technology	Li J (2013)	1
DLG4	11	ERBB2	6	two hybrid, affinity chromatography technology, biochemical	Huang YZ (2000), Huang YZ (2000), Huang YZ (2000)	3
EGFR	5	XPO1	8	affinity chromatography technology	Foerster S (2013)	1
MUC1	0	CTNNB1	30	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Yamamoto M (1997), Li Y (2003), Li Y (1998), Li Y (1998), Schroeder JA (2003), Yamamoto M (1997), Li Y (2001), Li Y (2001), Ren J (2002), Li Y (2001), Li Y (2001)	11
SRC	2	ERBB3	3	unspecified method	Jones RB (2006)	1
ERBB3	3	PTPN6	0	two hybrid	Yao Z (2017)	1
PLCG2	11	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Boudot C (2002), Boudot C (2002)	2
CBL	7	PTK2	2	imaging technique, affinity chromatography technology, affinity chromatography technology	Rafiq K (2011), Schmidt MH (2003), Sekine Y (2007)	3
PTK2	2	PIK3R1	6	affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guinebault C (1995), Guinebault C (1995), Lee DY (2010), Reddy MA (2000), Reiske HR (2000)	5
CDK4	2	ERBB2	6	genetic interference, fluorescent resonance energy transfe	Shen JP (2017), Ivanov AA (2017)	2
XPO1	8	SHC1	0	affinity chromatography technology	Kirli K (2015)	1
XPO1	8	CBL	7	affinity chromatography technology	Kirli K (2015)	1
PTPN11	20	PTPN6	0	affinity chromatography technology	Li X (2016)	1
SRC	2	GRB2	2	affinity chromatography technology, affinity chromatography technology	Wan KF (2003), Saci A (2002)	2
SRC	2	PTPN6	0	enzymatic study	Frank C (2004)	1
PIK3R2	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Huttlin EL (2015), Huttlin EL (2017)	3
CD44	1	ERBB2	6	affinity chromatography technology, fluorescent resonance energy transfe	Tsatas D (2002), Ivanov AA (2017)	2
ERBB2	6	PTPRR	3	two hybrid, affinity chromatography technology	Yao Z (2017), Yao Z (2017)	2
IL6ST	0	OSMR	1	affinity chromatography technology	Mosley B (1996)	1
ERBIN	5	ERBB2	6	pull down, two hybrid, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Jaulin-Bastard F (2001), Jaulin-Bastard F (2001), Jaulin-Bastard F (2001), Jaulin-Bastard F (2001), Borg JP (2000), Borg JP (2000), Huang YZ (2003)	7
MUC1	0	SRC	2	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology	Li Y (2001), Li Y (2001), Li Y (2001), Li Y (2001), Li Y (2001), Bernier AJ (2011)	6
EZR	8	ERBB2	6	fluorescent resonance energy transfe, imaging technique	Asp N (2016), Asp N (2016)	2
CBL	7	ACTB	8	affinity chromatography technology, affinity chromatography technology	Valiya Veettil M (2011), Brehme M (2009)	2
ERBB3	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hellyer NJ (2001), Lin J (1999), Crovello CS (1998), Graus-Porta D (1997), Jones RB (2006), Li J (2013), Servidei T (2008), Servidei T (2008), Ritch PS (2005), Tang X (2002)	10
ERBB2	6	PLCG2	11	unspecified method, imaging technique	Jones RB (2006), Chen TC (2014)	2
ERBB2	6	ACTB	8	affinity chromatography technology, imaging technique	Li LY (2011), Li LY (2011)	2
ERBB2	6	STAT1	1	unspecified method, imaging technique	Jones RB (2006), Chen TC (2014)	2
HSP90AA1	7	ERBB3	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Li J (2013)	2
ACTB	8	POLR1B	2	imaging technique	Li LY (2011)	1
OSMR	1	EGFR	5	affinity chromatography technology	Jahani-Asl A (2016)	1
PIK3R1	6	PLCG2	11	imaging technique	Chen TC (2014)	1
PIK3R1	6	EZR	8	affinity chromatography technology, pull down	Gautreau A (1999), Gautreau A (1999)	2
TGFBR2	0	PIK3R2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Krymskaya VP (1997), Huttlin EL (2015), Huttlin EL (2017)	3
CTNNB1	30	CBL	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Chitalia V (2013), Chitalia V (2013), Chitalia V (2013), Shivanna S (2015)	4
OSMR	1	ERBB2	6	affinity chromatography technology, imaging technique	Grant SL (2002), Chen TC (2014)	2
H2AFY	1	HSPA4	3	affinity chromatography technology	Ouararhni K (2006)	1
HSP90AA1	7	SRC	2	affinity chromatography technology, affinity chromatography technology	Hutchison KA (1992), Tsutsumi S (2012)	2
ITGAV	7	STAT1	1	affinity chromatography technology	Lin HY (2013)	1
ITGAV	7	SHC1	0	affinity chromatography technology	Lee DY (2010)	1
CDH2	4	JUP	7	affinity chromatography technology, affinity chromatography technology, biochemical	Straub BK (2003), Sacco PA (1995), Havugimana PC (2012)	3
PLCG1	6	ERBB3	3	unspecified method	Jones RB (2006)	1
ERBB2	6	PIK3R2	3	pull down, unspecified method	Gout I (1992), Jones RB (2006)	2
PLCG1	6	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Pei Z (1997), Pei Z (1997), Nel AE (1995), Scholler JK (2000), Choi JH (2005), Choi JH (2005)	6
GRB7	1	ERBB2	6	pull down, affinity chromatography technology, unspecified method	Janes PW (1997), Li X (2007), Jones RB (2006)	3
GRAP2	0	CBL	7	biochemical, affinity chromatography technology, two hybrid	Yankee TM (2003), Yankee TM (2003), Grossmann A (2015)	3
EGFR	5	STUB1	4	protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Deribe YL (2009), Wang T (2014), Wang T (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Chung C (2016), Chung C (2016)	8
DTWD2	4	ERBB2	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GRB2	2	PIK3R2	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bandyopadhyay S (2010), Brehme M (2009), Brehme M (2009), Bisson N (2011)	4
EGFR	5	CTNNB1	30	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hazan RB (1998), Schroeder JA (2002), Takahashi K (1997), Li J (2013)	4
SHC1	0	SRC	2	pull down	Schueller AC (2008)	1
ERBB2	6	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid	Schulze WX (2006), Wong L (1999), Olayioye MA (1998), Crovello CS (1998), Jones RB (2006), Yao Z (2017)	6
CTNNB1	30	PIK3R1	6	pull down, imaging technique	Espada J (1999), Chen TC (2014)	2
PTK2	2	STUB1	4	affinity chromatography technology	Lim ST (2012)	1
PIK3R2	3	ACTB	8	affinity chromatography technology	Brehme M (2009)	1
IL6ST	0	ERBB3	3	affinity chromatography technology	Grant SL (2002)	1
ERBIN	5	STAT3	0	two hybrid	Wang J (2011)	1
SRC	2	STAT3	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down	Cao X (1996), Cao X (1996), Yin N (2004), Yin N (2004), Jaganathan S (2011), Jaganathan S (2011), Gray MJ (2005), Schreiner SJ (2002)	8
ERBB2	6	XPO1	8	affinity chromatography technology, affinity chromatography technology	Giri DK (2005), Giri DK (2005)	2
ERBB2	6	PIK3R1	6	affinity chromatography technology, unspecified method	Crovello CS (1998), Jones RB (2006)	2
STAT3	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Gunaje JJ (2001), M L (2016)	2
EGFR	5	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marques MM (1999), Li J (2013), Li J (2013), Sharif A (2009)	4
ERRFI1	1	SHC1	0	affinity chromatography technology, affinity chromatography technology	Li J (2013), Li J (2013)	2
EGFR	5	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Olayioye MA (1999), Xia L (2002), Andl CD (2004), Foerster S (2013), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	8
HSP90AA1	7	TGFBR2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wrighton KH (2008), Wrighton KH (2008), Wrighton KH (2008), Zhang K (2012), Zhang K (2012)	5