PPI network (data source: BioGrid)

Symbol A GeneA coding DNM count Symbol B GeneB coding DNM count Interaction detection method Publication Evidence
ILK 0 RAF1 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Varjosalo M (2013), So J (2015), Hein MY (2015) 3
NPM1 0 CDC37 0 affinity chromatography technology Chen R (2013) 1
EGFR 5 APPL1 1 unspecified method Jones RB (2006) 1
AKT1 1 MAPK8IP1 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study Kim AH (2002), Song JJ (2005), Song JJ (2005), Nishitani Y (2006), Nishitani Y (2006) 5
TRAF6 0 BCL10 0 affinity chromatography technology Bidere N (2006) 1
PPL 6 VIM 0 two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid Kazerounian S (2002), van den Heuvel AP (2002), van den Heuvel AP (2002), van den Heuvel AP (2002), Rolland T (2014) 5
FOXO1 2 FOXO4 0 affinity chromatography technology Li X (2015) 1
AKT1 1 TERT 7 affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe Kawauchi K (2005), Kim MO (2008), Ivanov AA (2017) 3
MUL1 1 AKT1 1 pull down, affinity chromatography technology, enzymatic study Bae S (2012), Bae S (2012), Bae S (2012) 3
AKT1 1 SETDB1 3 two hybrid, pull down, affinity chromatography technology Gao H (2007), Gao H (2007), Gao H (2007) 3
AKT1 1 FOXO1 2 enzymatic study, enzymatic study, enzymatic study, enzymatic study, imaging technique Matsuzaki H (2005), Brent MM (2008), Rena G (1999), Tang ED (1999), Chen TC (2014) 5
EP300 36 YBX1 1 affinity chromatography technology Sengupta S (2011) 1
PIK3R1 6 PIK3CA 8 pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe Woscholski R (1994), Chamberlain MD (2004), Ren SY (2005), Kamal M (2010), Sun M (2010), Hein MY (2015), Fang D (2001), Xiong Y (2009), Ivanov AA (2017) 9
EP300 36 BRCA1 7 affinity chromatography technology, pull down, affinity chromatography technology, pull down, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Pao GM (2000), Pao GM (2000), Pao GM (2000), Pao GM (2000), Fan S (2002), Fan S (2002), Ma Y (2010), Subbaramaiah K (2011), Subbaramaiah K (2012) 9
RICTOR 4 CHUK 5 affinity chromatography technology, pull down Xu Y (2013), Xu Y (2013) 2
CDKN1A 1 SETDB1 3 two hybrid Vinayagam A (2011) 1
PRKDC 12 CHUK 5 enzymatic study, pull down Liu L (1998), Liu L (1998) 2
PRKCZ 5 NPM1 0 affinity chromatography technology, affinity chromatography technology Chen R (2013), Chen R (2013) 2
HSP90AA1 7 VCP 6 affinity chromatography technology, affinity chromatography technology Vij N (2006), Yu CC (2013) 2
AGAP2 14 PIK3R1 6 pull down, affinity chromatography technology Ye K (2000), Ye K (2000) 2
BRCA1 7 AR 3 pull down, pull down, two hybrid Park JJ (2000), Yeh S (2000), Yeh S (2000) 3
STK4 1 SIRT1 3 enzymatic study Yuan F (2011) 1
EGFR 5 AKT1 1 two hybrid, protein complementation assay, affinity chromatography technology Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014) 3
TCL1A 0 EP300 36 affinity chromatography technology, affinity chromatography technology Pekarsky Y (2008), Pekarsky Y (2008) 2
ALYREF 0 YBX1 1 biochemical Havugimana PC (2012) 1
PRKDC 12 GSK3B 1 enzymatic study Dragoi AM (2005) 1
BRCA1 7 XIAP 0 affinity chromatography technology, pull down Martin SA (2005), Martin SA (2005) 2
AKT1 1 DNMT1 5 enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down Esteve PO (2011), Esteve PO (2011), Esteve PO (2011), Esteve PO (2011) 4
ILK 0 ALYREF 0 affinity chromatography technology So J (2015) 1
SKP2 2 CCDC88A 3 affinity chromatography technology Huttlin EL (2017) 1
MTOR 14 PRKDC 12 genetic interference Shen JP (2017) 1
CDKN1B 1 SIRT6 2 affinity chromatography technology, affinity chromatography technology, pull down, pull down Zhao G (2016), Zhao G (2016), Zhao G (2016), Zhao G (2016) 4
PIK3R1 6 DAB2IP 3 pull down, affinity chromatography technology, affinity chromatography technology Xie D (2009), Xie D (2009), Xie D (2009) 3
MXD1 2 AKT1 1 affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, enzymatic study Chou CK (2009), Chou CK (2009), Chou CK (2009), Chou CK (2009), Chou CK (2009), Zhu J (2008) 6
RGCC 0 AKT1 1 pull down, affinity chromatography technology, enzymatic study Fosbrink M (2009), Fosbrink M (2009), Fosbrink M (2009) 3
AKT1 1 AR 3 pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Lin HK (2001), Lin HK (2001), Deep G (2008), Deep G (2008), Steely AM (2017) 5
BRCA1 7 SKP2 2 affinity chromatography technology, affinity chromatography technology, enzymatic study Lu Y (2012), Lu Y (2012), Parameswaran B (2015) 3
CDC37 0 RAF1 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014), Li J (2013) 3
MDM2 2 SIRT1 3 affinity chromatography technology, enzymatic study, affinity chromatography technology Nihira NT (2017), Nihira NT (2017), Nihira NT (2017) 3
TBK1 1 XIAP 0 enzymatic study, enzymatic study Nakhaei P (2012), Kuranaga E (2006) 2
VCP 6 RAF1 3 affinity chromatography technology Yu CC (2013) 1
CDC37 0 MTOR 14 two hybrid Vinayagam A (2011) 1
PPP1CA 3 AKT1 1 enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Li L (2003), Xiao L (2010), Xiao L (2010), Xiao L (2010), Chen CS (2005), Chen CS (2005) 6
ARRB2 5 VCP 6 affinity chromatography technology Xiao K (2007) 1
ARRB2 5 MAP2K4 3 affinity chromatography technology, unspecified method McDonald PH (2000), Li X (2009) 2
SRPK2 1 CHUK 5 enzymatic study Varjosalo M (2013) 1
HSP90AA1 7 PRKDC 12 affinity chromatography technology Falsone SF (2005) 1
EGFR 5 PRKCZ 5 two hybrid, protein complementation assay Kotlyar M (2015), Petschnigg J (2014) 2
STK3 1 AKT1 1 affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study Romano D (2010), Romano D (2010), Kim D (2010), Kim D (2010), Kim D (2010) 5
ITPR1 25 BRCA1 7 pull down, affinity chromatography technology, biochemical, fluorescent resonance energy transfe Hedgepeth SC (2015), Hedgepeth SC (2015), Hedgepeth SC (2015), Hedgepeth SC (2015) 4
TRAF6 0 TBK1 1 affinity chromatography technology, affinity chromatography technology, pull down Cai B (2017), Fang R (2017), Fang R (2017) 3
EGFR 5 NPM1 0 affinity chromatography technology Liccardi G (2014) 1
EP300 36 TNK2 7 affinity chromatography technology Guidez F (2005) 1
BRAF 12 BAD 1 enzymatic study Polzien L (2009) 1
FANCA 5 AKT1 1 two hybrid, enzymatic study, affinity chromatography technology Reuter TY (2003), Otsuki T (2002), Otsuki T (2002) 3
HSPB1 2 TTC3 1 two hybrid Katsogiannou M (2014) 1
VIM 0 SETDB1 3 two hybrid Goehler H (2004) 1
MAPK14 0 TSC1 4 two hybrid, affinity chromatography technology, fluorescent resonance energy transfe Pilot-Storck F (2010), Pilot-Storck F (2010), Ivanov AA (2017) 3
BRAF 12 EGFR 5 genetic interference Shen JP (2017) 1
TERT 7 MDM2 2 affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, pull down Oh W (2010), Oh W (2010), Oh W (2010), Oh W (2010), Hu C (2015), Hu C (2015) 6
ILK 0 RICTOR 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid McDonald PC (2008), McDonald PC (2008), McDonald PC (2008), McDonald PC (2008) 4
SKP2 2 CDKN1A 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, imaging technique Amador V (2007), Hwang CY (2007), Calvisi DF (2009), Bendjennat M (2003), Wu L (2012), Wu L (2012), Abbas T (2008), Ungermannova D (2005), Chen TC (2014) 9
MTOR 14 TERT 7 affinity chromatography technology Kawauchi K (2005) 1
HSP90AA1 7 BRCA1 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Johnson N (2013), Johnson N (2013), Ertych N (2016) 3
ARRB2 5 ALYREF 0 affinity chromatography technology Xiao K (2007) 1
VHL 0 AR 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down Chen S (2013), Chen S (2013), Wang J (2014), Wang J (2014) 4
VCP 6 CDKN1B 1 affinity chromatography technology Yu CC (2013) 1
PIK3R1 6 BRCA1 7 pull down Ren SY (2005) 1
SIRT1 3 YBX1 1 affinity chromatography technology Law IK (2009) 1
AR 3 RAF1 3 biochemical Kupfer SR (1993) 1
SKP2 2 AR 3 imaging technique, affinity chromatography technology Li B (2014), Li B (2014) 2
NEDD4 2 SMARCC1 5 pull down Ingham RJ (2005) 1
HSP90AA1 7 BRAF 12 affinity chromatography technology, affinity chromatography technology Taipale M (2012), Eisenhardt AE (2016) 2
ARRB2 5 TRAF6 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Wang Y (2006), Wang Y (2006), Xiao N (2015) 3
EGFR 5 XIAP 0 affinity chromatography technology Yao Z (2017) 1
BRAF 12 CDC37 0 affinity chromatography technology, affinity chromatography technology Gloeckner CJ (2007), Eisenhardt AE (2016) 2
AKT1 1 TTC3 1 affinity chromatography technology, enzymatic study, pull down Suizu F (2009), Suizu F (2009), Suizu F (2009) 3
HSP90AA1 7 GSK3A 1 affinity chromatography technology, affinity chromatography technology Taipale M (2012), Taipale M (2012) 2
SNAI1 1 DNMT1 5 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Liu T (2017), Yuan K (2016), Yuan K (2016) 3
CDKN1C 0 AKT1 1 affinity chromatography technology, affinity chromatography technology, enzymatic study Zhao R (2013), Zhao R (2013), Zhao R (2013) 3
UBE2S 2 VHL 0 pull down, pull down, enzymatic study, affinity chromatography technology Lim JH (2016), Lim JH (2016), Lim JH (2016), Lim JH (2016) 4
YWHAZ 1 VIM 0 affinity chromatography technology, affinity chromatography technology, pull down Tzivion G (2000), Tzivion G (2000), Tzivion G (2000) 3
AKT1 1 PIK3R1 6 affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe Xiong Y (2009), Xiong Y (2009), Ivanov AA (2017) 3
AR 3 SMARCB1 1 bioid Lempiaeinen JK (2017) 1
TRAF6 0 FANCA 5 affinity chromatography technology Karras GI (2017) 1
YWHAZ 1 PRKCZ 5 pull down, enzymatic study Zemlickova E (2003), Van Der Hoeven PC (2000) 2
BRCA1 7 ARNT 1 affinity chromatography technology, pull down, affinity chromatography technology Kang HJ (2006), Kang HJ (2006), Kang HJ (2006) 3
NEDD4 2 RAF1 3 pull down Persaud A (2009) 1
GSK3B 1 TSC1 4 affinity chromatography technology Mak BC (2003) 1
SKP2 2 CDKN1B 1 enzymatic study, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology Wang W (2003), Sitry D (2002), Fujita N (2002), Ji P (2006), Zancai P (2005), Ji P (2004), Iovine B (2011), Calvisi DF (2009), Spruck C (2001), Bashir T (2010), Bashir T (2010), Li P (2004), Boutonnet C (2010), Rosner M (2004), Rosner M (2004), Carrano AC (1999), Carrano AC (1999), Carrano AC (1999), Wu J (2012), Strohmaier H (2001), Rodier G (2008), Rodier G (2008), Ooi LC (2013), Yumimoto K (2013), Ooi LC (2013), Cen B (2010), Enchev RI (2012), Yumimoto K (2012), Shi P (2011), Lovisa S (2016), Cen B (2009), Chan CH (2013), Ma X (2017) 33
IMPDH2 3 SKP2 2 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
XIAP 0 AKT1 1 affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique Dan HC (2004), Dan HC (2004), Pramanik KC (2013), Pramanik KC (2013), Chen TC (2014) 5
VHL 0 SIRT1 3 affinity chromatography technology Ji W (2014) 1
VHL 0 PPP2CA 7 affinity chromatography technology, affinity chromatography technology Guo J (2016), Guo J (2016) 2
RARA 5 NPM1 0 affinity chromatography technology McNamara S (2008) 1
AKT1 1 BAD 1 pull down, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, imaging technique Wang X (2001), Deregibus MC (2002), Song JJ (2005), Song JJ (2005), Polzien L (2009), Urschel S (2005), Yuan ZQ (2005), Rena G (1999), Kim J (2013), Chen TC (2014) 10
AKT1 1 TRIB3 0 pull down, affinity chromatography technology, two hybrid Du K (2003), Du K (2003), Du K (2003) 3
AKT1 1 YBX1 1 affinity chromatography technology, pull down, enzymatic study, imaging technique, enzymatic study, affinity chromatography technology, pull down Sutherland BW (2005), Sutherland BW (2005), Sutherland BW (2005), Sutherland BW (2005), Evdokimova V (2006), Evdokimova V (2006), Evdokimova V (2006) 7
CHUK 5 PPP1CA 3 affinity chromatography technology, affinity chromatography technology Mitsuhashi S (2008), Mitsuhashi S (2008) 2
AKT1 1 CCDC88A 3 two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down Enomoto A (2005), Enomoto A (2005), Anai M (2005), Anai M (2005), Anai M (2005) 5
YWHAZ 1 CDKN1B 1 pull down Sekimoto T (2004) 1
TRAF6 0 XIAP 0 affinity chromatography technology, two hybrid, imaging technique Sanna MG (2002), Woodsmith J (2012), Chen TC (2014) 3
CLK2 2 BRCA1 7 two hybrid, affinity chromatography technology Hill SJ (2014), Hill SJ (2014) 2
CDKN1A 1 FOXO1 2 imaging technique Chen TC (2014) 1
EZH2 4 VCP 6 affinity chromatography technology Cao Q (2014) 1
CHUK 5 TRAF6 0 affinity chromatography technology Kishida S (2005) 1
VHL 0 IMPDH2 3 affinity chromatography technology Ewing RM (2007) 1
SMARCB1 1 VIM 0 two hybrid Daakour S (2016) 1
YWHAZ 1 MAPKAPK2 1 pull down, pull down, enzymatic study Powell DW (2003), Powell DW (2003), Powell DW (2003) 3
GSK3B 1 MTOR 14 two hybrid Vinayagam A (2011) 1
AKT1 1 MAP3K8 2 affinity chromatography technology, affinity chromatography technology, enzymatic study Kane LP (2002), Kane LP (2002), Kane LP (2002) 3
FANCA 5 IKBKB 1 two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology Otsuki T (2002), Otsuki T (2002), Otsuki T (2002), Otsuki T (2002) 4
EGFR 5 MAPK8IP1 7 unspecified method Jones RB (2006) 1
NPM1 0 IMPDH2 3 affinity chromatography technology Chen R (2013) 1
AKT1 1 GSK3B 1 pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study Thimmaiah KN (2005), Drendall CI (2010), Connor MK (2005), Hunter MG (2004), Zhu QS (2011), Li L (2003), Nam SY (2010), Yang WL (2009), Zeng L (2013), Yang H (2005), Boehme KA (2008), Cross DA (1995), Hinton CV (2007), Kapoor GS (2004), Pitre A (2012), Guo J (2016) 16
HSPB1 2 VIM 0 two hybrid Katsogiannou M (2014) 1
FANCA 5 CHUK 5 two hybrid, affinity chromatography technology Reuter TY (2003), Otsuki T (2002) 2
EGFR 5 PIK3R1 6 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, imaging technique Tong J (2009), Wen G (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Chen TC (2014) 6
VCP 6 UBE2S 2 affinity chromatography technology Yu CC (2013) 1
EP300 36 SKP2 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down Kitagawa M (2008), Inuzuka H (2012), Inuzuka H (2012), Oh M (2016) 4
VCP 6 MTOR 14 affinity chromatography technology Yu CC (2013) 1
AKTIP 3 PRKDC 12 affinity chromatography technology Subramanian PD (2016) 1
SIRT1 3 MTOR 14 affinity chromatography technology, affinity chromatography technology Back JH (2011), Singh BK (2016) 2
MDM2 2 EZH2 4 affinity chromatography technology, affinity chromatography technology Wienken M (2016), Wienken M (2016) 2
GSK3B 1 MDM2 2 enzymatic study, affinity chromatography technology Kulikov R (2005), Kulikov R (2005) 2
PRKDC 12 AR 3 affinity chromatography technology Mayeur GL (2005) 1
AGAP2 14 AKT1 1 pull down, fluorescent resonance energy transfe, affinity chromatography technology Qi Q (2013), Qi Q (2013), Qi Q (2013) 3
SNAI1 1 MDM2 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Lim SO (2011), Lim SO (2010), Lim SO (2010) 3
SIRT1 3 DNMT1 5 enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Peng L (2011), Peng L (2011), Peng L (2011), OHagan HM (2011), OHagan HM (2011) 5
SKP2 2 RICTOR 4 affinity chromatography technology Huttlin EL (2017) 1
AKT1 1 GSK3A 1 enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study Drendall CI (2010), Nakamura H (2001), Ma Y (2007), Li L (2003), Sundaresan NR (2011), Dragoi AM (2005), Dixon DA (2006), Sun L (2012), Kapoor GS (2004), Hellyer NJ (2001) 10
PRKDC 12 VHL 0 genetic interference Shen JP (2017) 1
EGFR 5 YWHAZ 1 affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology Tong J (2009), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014) 5
EP300 36 YWHAZ 1 enzymatic study Mortenson JB (2015) 1
HSP90AA1 7 TBK1 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Yang K (2006), Taipale M (2012), Liu XY (2010) 3
AKT1 1 SNAI1 1 pull down, affinity chromatography technology, pull down, affinity chromatography technology Villagrasa P (2012), Villagrasa P (2012), Villagrasa P (2012), Villagrasa P (2012) 4
MAPK14 0 ARNT 1 fluorescent resonance energy transfe Ivanov AA (2017) 1
HSP90AA1 7 ILK 0 affinity chromatography technology Taipale M (2012) 1
TCL1A 0 AKT1 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, two hybrid Laine J (2002), Laine J (2000), French SW (2002), French SW (2002), Rolland T (2014), Daakour S (2016) 6
SIRT1 3 TSC2 17 affinity chromatography technology, affinity chromatography technology Ghosh HS (2010), Ghosh HS (2010) 2
HSPB1 2 IKBKB 1 affinity chromatography technology Kammanadiminti SJ (2006) 1
CLK2 2 AKT1 1 pull down, affinity chromatography technology, enzymatic study Nam SY (2010), Nam SY (2010), Nam SY (2010) 3
CDC37 0 AKT1 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down Basso AD (2002), Basso AD (2002), Kim H (2014), Sun L (2012) 4
EGFR 5 HSP90AA1 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay Citri A (2002), Yang S (2006), Shimamura T (2005), Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014) 8
SKP2 2 AKT1 1 affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Roe JS (2011), Gao D (2009), Gao D (2009), Chan CH (2013) 9
APPL1 1 TRAF6 0 affinity chromatography technology Cheng KK (2013) 1
RAF1 3 NF2 1 fluorescent resonance energy transfe Ivanov AA (2017) 1
SIRT1 3 HSP90AA1 7 affinity chromatography technology, affinity chromatography technology Lin Z (2012), Hein MY (2015) 2
ARRB2 5 NPM1 0 affinity chromatography technology Xiao K (2007) 1
CHUK 5 MTOR 14 affinity chromatography technology, affinity chromatography technology, biochemical Dan HC (2008), Dan HC (2008), Dan HC (2008) 3
MAPKAPK2 1 HSPB1 2 affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, imaging technique, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study Rane MJ (2001), Uddin S (2002), Coxon PY (2003), Rogalla T (1999), Werz O (2002), Clifton AD (1996), Rane MJ (2001), Sun L (2007), Chen TC (2014), Krump E (1997), Chrestensen CA (2004), Chang E (2011), Maitra S (2008), Rane MJ (2003), Singh S (2003), Chen G (2000), Eyers CE (2005), Tollenaere MA (2015) 18
CDKN1A 1 MDM2 2 affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe, affinity chromatography technology, imaging technique Zhang Z (2004), Zhang Z (2004), Zhang Z (2004), Jin Y (2003), Jin Y (2003), Wang B (2010), Xu H (2010), Xu H (2010), Frum R (2007), Chen TC (2014) 10
NPM1 0 BRCA1 7 affinity chromatography technology, affinity chromatography technology Sato K (2004), Ertych N (2016) 2
CLK2 2 SRPK2 1 two hybrid, two hybrid Rolland T (2014), Yu H (2011) 2
TBK1 1 GSK3B 1 affinity chromatography technology, affinity chromatography technology Qin Y (2016), Qin Y (2016) 2
BRCA1 7 HSPB1 2 affinity chromatography technology Ertych N (2016) 1
AKT1 1 MAPK14 0 affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, fluorescent resonance energy transfe Rane MJ (2001), Rane MJ (2001), Hartman AD (2006), Rane MJ (2001), Rane MJ (2001), Ivanov AA (2017) 6
EGFR 5 RAF1 3 two hybrid, protein complementation assay Kotlyar M (2015), Petschnigg J (2014) 2
HSPB1 2 CHUK 5 affinity chromatography technology Kammanadiminti SJ (2006) 1
PPP2CA 7 CHUK 5 affinity chromatography technology Kray AE (2005) 1
AKT1 1 AKT1 1 enzymatic study, affinity chromatography technology, enzymatic study, fluorescent resonance energy transfe Yeh PY (2006), Kawase T (2009), Yuan ZQ (2005), Ivanov AA (2017) 4
EZH2 4 AKT1 1 affinity chromatography technology, affinity chromatography technology, enzymatic study Cha TL (2005), Cha TL (2005), Cha TL (2005) 3
ARRB2 5 YBX1 1 affinity chromatography technology Xiao K (2007) 1
EP300 36 PRKDC 12 pull down Karmakar S (2010) 1
NF2 1 TERT 7 fluorescent resonance energy transfe Ivanov AA (2017) 1
AKT1 1 JADE1 6 affinity chromatography technology, affinity chromatography technology, imaging technique, pull down Zeng L (2013), Zeng L (2013), Zeng L (2013), Zeng L (2013) 4
HSP90AA1 7 AKT1 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down Haendeler J (2003), Kawauchi K (2005), Sato S (2000), Basso AD (2002), Su CH (2011), Klein JB (2005), Sun L (2012) 7
CHUK 5 CDC37 0 pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Chen G (2002), Li S (2011), Taipale M (2014), Taipale M (2014), Li J (2013) 5
SIRT1 3 RICTOR 4 enzymatic study, affinity chromatography technology Glidden EJ (2012), Singh BK (2016) 2
VCP 6 VIM 0 affinity chromatography technology Yu CC (2013) 1
HSP90AA1 7 SKP2 2 affinity chromatography technology Taipale M (2012) 1
EP300 36 FOXO1 2 enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology Brent MM (2008), Perrot V (2005), Perrot V (2005), Perrot V (2005), Perrot V (2005), Pramanik KC (2014), Pramanik KC (2014), Mahmud DL (2002), Li X (2015) 9
CCDC88A 3 EGFR 5 imaging technique Simpson F (2005) 1
ILK 0 PRKDC 12 affinity chromatography technology, affinity chromatography technology Varjosalo M (2013), So J (2015) 2
ILK 0 AKT1 1 affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology Barry FA (2002), Delcommenne M (1998), Persad S (2001), McDonald PC (2008) 4
MTOR 14 YWHAZ 1 affinity chromatography technology, genetic interference Vander Haar E (2007), Srivas R (2016) 2
ARRB2 5 CHUK 5 affinity chromatography technology, imaging technique Xiao K (2007), Chen TC (2014) 2
MAPKAP1 0 AKT1 1 affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, two hybrid, pull down Jacinto E (2006), Murata H (2011), Facchinetti V (2008), Facchinetti V (2008), Tatebe H (2017), Tatebe H (2017) 6
TSC1 4 AKT1 1 affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe Roux PP (2004), Dan HC (2002), Ivanov AA (2017) 3
BRCA1 7 SMARCC1 5 biochemical, affinity chromatography technology Bochar DA (2000), Ertych N (2016) 2
EZH2 4 HSPB1 2 affinity chromatography technology Cao Q (2014) 1
RICTOR 4 MAPKAP1 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology Jacinto E (2006), Yang Q (2006), Jacinto E (2006), Pearce LR (2007), Pearce LR (2007), Gao D (2010), Gao D (2010), Oh WJ (2010), Oh WJ (2010), Yang Q (2006), Jacinto E (2006), Jacinto E (2006), Ikenoue T (2008), Murata H (2011), Murata H (2011), Koike-Kumagai M (2009), Koike-Kumagai M (2009), Martin J (2008), Thedieck K (2007), Hong F (2008), Facchinetti V (2008), Chen CH (2011), Glidden EJ (2012), Thedieck K (2007) 24
GSK3B 1 RICTOR 4 enzymatic study, affinity chromatography technology, enzymatic study Chen CH (2011), Koo J (2015), Koo J (2015) 3
SKP2 2 PHLPP1 4 affinity chromatography technology Huttlin EL (2017) 1
FANCI 1 IMPDH2 3 biochemical Wan C (2015) 1
NPM1 0 HSPB1 2 affinity chromatography technology Chen R (2013) 1
PPP1CA 3 GSK3B 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Tanji C (2002), Varjosalo M (2013), St-Denis N (2016) 3
PRKDC 12 BRCA1 7 unspecified method Kim ST (1999) 1
MDM2 2 NEDD4 2 unspecified method, enzymatic study, affinity chromatography technology Burch LR (2004), Xu C (2014), Xu C (2014) 3
MDM2 2 NPM1 0 affinity chromatography technology, pull down, unspecified method, affinity chromatography technology Kurki S (2004), Kurki S (2004), Nicholson J (2012), Nicholson J (2012) 4
SMARCB1 1 PPP1CA 3 pull down, affinity chromatography technology, genetic interference Wu DY (2002), Wu DY (2002), Wu DY (2002) 3
BRCA1 7 VCP 6 affinity chromatography technology, pull down, affinity chromatography technology Zhang H (2000), Zhang H (2000), Ertych N (2016) 3
YWHAZ 1 RAF1 3 pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe Clark GJ (1997), Tzivion G (2000), Tzivion G (2000), Koyama S (1995), Koyama S (1995), Van Der Hoeven PC (2000), Chow CW (2000), Andersen SD (2012), Subramanian RR (2001), Wang H (1998), Wang H (1998), Wang H (1998), Dougherty MK (2005), Rajalingam K (2005), Zhu J (2005), So J (2015), Powell DW (2003), Ivanov AA (2017) 18
TSC2 17 AKT1 1 affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology Dan HC (2002), Roux PP (2004), Dan HC (2002), Dan HC (2002) 4
RAF1 3 ARNT 1 fluorescent resonance energy transfe Ivanov AA (2017) 1
TNK2 7 NEDD4 2 affinity chromatography technology, enzymatic study, pull down, pull down, affinity chromatography technology Lin Q (2010), Lin Q (2010), Lin Q (2010), Lin Q (2010), Hitomi Y (2013) 5
SNAI1 1 GSK3B 1 affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Yook JI (2005), Zhou BP (2004), Zhou BP (2004), Wu Y (2009), Wu Y (2009), Lee JH (2017) 6
TSC2 17 YWHAZ 1 two hybrid, pull down, affinity chromatography technology Nellist M (2002), Nellist M (2002), Hernandez G (2011) 3
EGFR 5 ARRB2 5 two hybrid, protein complementation assay Kotlyar M (2015), Petschnigg J (2014) 2
SKP2 2 SIRT6 2 pull down Inuzuka H (2012) 1
PDPK1 0 SMARCB1 1 two hybrid Vinayagam A (2011) 1
TERT 7 YWHAZ 1 two hybrid Seimiya H (2000) 1
CLIP3 4 AKT1 1 affinity chromatography technology, affinity chromatography technology, pull down Ding J (2009), Ding J (2009), Ding J (2009) 3
SIRT6 2 FANCA 5 affinity chromatography technology Karras GI (2017) 1
GSK3B 1 AR 3 pull down, affinity chromatography technology Wang L (2004), Wang L (2004) 2
SIRT6 2 VIM 0 two hybrid, two hybrid Stelzl U (2005), Vinayagam A (2011) 2
BAD 1 CDKN1A 1 two hybrid Wang J (2011) 1
TNK2 7 AR 3 affinity chromatography technology, pull down Mahajan NP (2007), Mahajan NP (2007) 2
AKT1 1 ARRB2 5 affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology Beaulieu JM (2008), Beaulieu JM (2008), Lodeiro M (2009), Luan B (2009) 4
VCP 6 SMARCC1 5 affinity chromatography technology Yu CC (2013) 1
NPM1 0 HSP90AA1 7 affinity chromatography technology Chen R (2013) 1
BRAF 12 CCDC88A 3 two hybrid Bandyopadhyay S (2010) 1
AKT1 1 CDKN1A 1 pull down, enzymatic study, imaging technique, enzymatic study Heron-Milhavet L (2006), Heron-Milhavet L (2006), Chen TC (2014), Roessig L (2001) 4
GNB1 4 PIK3CA 8 affinity chromatography technology Xiong Y (2009) 1
SKP2 2 STK3 1 affinity chromatography technology Huttlin EL (2017) 1
NOS3 7 AKT1 1 affinity chromatography technology, affinity chromatography technology, enzymatic study, imaging technique Brouet A (2001), Brouet A (2001), Dimmeler S (1999), Chen TC (2014) 4
BAD 1 PPP1CA 3 affinity chromatography technology Flores-Delgado G (2007) 1
BRAF 12 PIK3CA 8 genetic interference Shen JP (2017) 1
EP300 36 PPP2CA 7 affinity chromatography technology Chen J (2005) 1
FOXO1 2 RARA 5 pull down Zhao HH (2001) 1
ARRB2 5 SRPK2 1 affinity chromatography technology Xiao K (2007) 1
NF2 1 EGFR 5 affinity chromatography technology, fluorescent resonance energy transfe Guerrero PA (2015), Ivanov AA (2017) 2
YWHAZ 1 BRAF 12 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe Ewing RM (2007), Jin J (2004), Gloeckner CJ (2007), Hein MY (2015), Huttlin EL (2017), Eisenhardt AE (2016), Ivanov AA (2017) 7
APPL1 1 PIK3R1 6 affinity chromatography technology, two hybrid Yang L (2003), Grossmann A (2015) 2
BRAF 12 VIM 0 affinity chromatography technology Eisenhardt AE (2016) 1
FOXO4 0 AKT1 1 affinity chromatography technology, pull down, enzymatic study Yang H (2005), Yang H (2005), Matsuzaki H (2005) 3
CDKN1A 1 USP4 3 two hybrid Vinayagam A (2011) 1
CDKN1A 1 EP300 36 pull down, affinity chromatography technology Cazzalini O (2008), Cazzalini O (2008) 2
MDM2 2 XIAP 0 pull down, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method Gu L (2009), Huang X (2013), Huang X (2013), Huang X (2013), Liu T (2015) 5
BRCA1 7 MAPKAP1 0 affinity chromatography technology Woods NT (2012) 1
AKT1 1 BCL10 0 affinity chromatography technology, affinity chromatography technology, enzymatic study Yeh PY (2006), Yeh PY (2006), Yeh PY (2006) 3
EGFR 5 MAP2K4 3 affinity chromatography technology Tong J (2014) 1
YWHAZ 1 BAD 1 pull down, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Yang H (2001), Yang H (2001), Bandyopadhyay S (2010), Liang X (2010), Subramanian RR (2001), Polzien L (2009), Wang J (2011), Jin L (2009), Mortenson JB (2015), Dong S (2007) 10
PDPK1 0 AKT1 1 affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology Barry FA (2002), Persad S (2001), Lin K (2012), Guo J (2016), Guo J (2016) 5
EGFR 5 TNK2 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology Lin Q (2010), Pao-Chun L (2009), Shen F (2007), Howlin J (2008), Howlin J (2008), Tong J (2008), Jones S (2014), Jones S (2014), Chua BT (2010) 9
ARRB2 5 NEDD4 2 affinity chromatography technology, affinity chromatography technology Shenoy SK (2008), Han SO (2012) 2
MAPK14 0 EGFR 5 enzymatic study Raingeaud J (1995) 1
NF2 1 ARNT 1 fluorescent resonance energy transfe Ivanov AA (2017) 1
GSK3B 1 HSP90AA1 7 enzymatic study Muller P (2012) 1
VHL 0 HSP90AA1 7 affinity chromatography technology, genetic interference Yang C (2013), Shen JP (2017) 2
NEDD4 2 TBK1 1 pull down Persaud A (2009) 1
CDC37 0 FKBP5 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014) 4
MAPK14 0 HSPB1 2 enzymatic study Morley SJ (2000) 1
FANCI 1 AKT1 1 affinity chromatography technology, affinity chromatography technology, pull down Zhang X (2016), Zhang X (2016), Zhang X (2016) 3
MTOR 14 SKP2 2 affinity chromatography technology, affinity chromatography technology, enzymatic study Geng Q (2017), Geng Q (2017), Geng Q (2017) 3
PDPK1 0 PRKCZ 5 two hybrid, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down Balendran A (2000), Hodgkinson CP (2002), Hodgkinson CP (2002), Le Good JA (1998), Le Good JA (1998), Le Good JA (1998), Balendran A (2000), Park J (1999) 8
BRCA1 7 RICTOR 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Woods NT (2012), Woods NT (2012), Woods NT (2012) 3
CDKN1B 1 TSC2 17 affinity chromatography technology, affinity chromatography technology Rosner M (2004), Rosner M (2007) 2
AKT1 1 RAF1 3 enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe Zimmermann S (1999), Zimmermann S (1999), Wang J (2009), Wang J (2009), Ivanov AA (2017) 5
GSK3A 1 AR 3 affinity chromatography technology Mazor M (2004) 1
ARRB2 5 MDM2 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, two hybrid, two hybrid, affinity chromatography technology Wang P (2003), Wang P (2003), Wang P (2003), Shenoy SK (2008), Shenoy SK (2001), Ahmed MR (2011), Yin C (2011), Yin C (2011), Yin C (2011), Girnita L (2005), Girnita L (2005), Nogues L (2011), Boularan C (2007), Boularan C (2007), Wang J (2011), Shenoy SK (2001), Zheng M (2015) 17
SIRT6 2 IMPDH2 3 affinity chromatography technology Simeoni F (2013) 1
FKBP5 0 ILK 0 affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014) 2
PRKDC 12 YBX1 1 biochemical Havugimana PC (2012) 1
MAP3K8 2 MAP2K4 3 enzymatic study Salmeron A (1996) 1
YBX1 1 SRPK2 1 affinity chromatography technology Palicharla VR (2015) 1
EGFR 5 UBE2S 2 affinity chromatography technology Tong J (2014) 1
SMARCB1 1 AKT1 1 affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down Foster KS (2006), Foster KS (2006), Foster KS (2006), Foster KS (2006) 4
BCL10 0 IKBKB 1 affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology Lobry C (2007), Lobry C (2007), Poyet JL (2001), Zhou H (2004), Bidere N (2009) 5
HSPB1 2 HSP90AA1 7 two hybrid Katsogiannou M (2014) 1
AKT1 1 EP300 36 affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down Lin WN (2008), Lee IT (2010), Sundaresan NR (2011), Howie HL (2011), Chen J (2004), Chen J (2004) 6
SNAI1 1 EP300 36 affinity chromatography technology Hsu DS (2014) 1
HSP90AA1 7 CDKN1B 1 genetic interference Srivas R (2016) 1
GSK3A 1 RICTOR 4 affinity chromatography technology, enzymatic study Koo J (2015), Koo J (2015) 2
RICTOR 4 IKBKB 1 affinity chromatography technology, pull down Xu Y (2013), Xu Y (2013) 2
GNB1 4 PIK3R1 6 affinity chromatography technology, affinity chromatography technology Xiong Y (2009), Xiong Y (2009) 2
HSP90AA1 7 CHUK 5 affinity chromatography technology, affinity chromatography technology Qu X (2012), Gano JJ (2010) 2
TRIB3 0 SETDB1 3 two hybrid Stelzl U (2005) 1
HSP90AA1 7 NOS3 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology Venema RC (2003), Venema RC (2003), Harris MB (2000), Harris MB (2000), Stepp DW (2002), Fontana J (2002), Fontana J (2002), Brouet A (2001), Brouet A (2001) 9
AKT1 1 CDKN1B 1 enzymatic study, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology Fujita N (2002), Fujita N (2002), Nacusi LP (2006), Chen TC (2014), Zhang H (2017), Zhang H (2017) 6
MDM2 2 SETDB1 3 two hybrid Wang J (2011) 1
SIRT6 2 PRKDC 12 affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology McCord RA (2009), McCord RA (2009), McCord RA (2009), Simeoni F (2013) 4
TBK1 1 CDC37 0 affinity chromatography technology Bouwmeester T (2004) 1
AKT1 1 HSPB1 2 affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down, enzymatic study Rane MJ (2001), Rane MJ (2001), Rane MJ (2001), Wu R (2007), Wu R (2007), Wu R (2007), Rane MJ (2003), Rane MJ (2003), Rane MJ (2003) 9
IKBKB 1 PPP1CA 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Li HY (2008), Mitsuhashi S (2008), Mitsuhashi S (2008) 3
FOXO1 2 SIRT1 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Kitamura YI (2005), Bastien-Dionne PO (2011), Yang Y (2005), Yang Y (2005) 4
AR 3 PPP1CA 3 affinity chromatography technology, affinity chromatography technology Liu X (2016), Liu X (2016) 2
NEDD4 2 STK4 1 pull down Persaud A (2009) 1
BRAF 12 RAF1 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Weber CK (2001), Weber CK (2001), Kilili GK (2010), Chen C (2008), Chen C (2008), Lito P (2012), Huttlin EL (2017) 7
NOS3 7 CDC37 0 affinity chromatography technology, two hybrid, pull down Soler-Lopez M (2011), Soler-Lopez M (2011), Soler-Lopez M (2011) 3
CDC37 0 AR 3 pull down Rao J (2001) 1
EZH2 4 DNMT1 5 pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Vire E (2006), Vire E (2006), Vire E (2006), Xu B (2011), OHagan HM (2011) 5
AKT1 1 PPP2CA 7 affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study Beaulieu JM (2008), Beaulieu JM (2008), Calvo N (2010), Calvo N (2010), Xiao L (2010), Guo J (2016), Guo J (2016), Guo J (2016) 8
PPP1CA 3 MDM2 2 affinity chromatography technology Liu X (2016) 1
FANCA 5 HSP90AA1 7 two hybrid Reuter TY (2003) 1
BRAF 12 TERT 7 fluorescent resonance energy transfe Ivanov AA (2017) 1
PRKCZ 5 GSK3B 1 imaging technique Chen TC (2014) 1
SORBS3 5 AKT1 1 affinity chromatography technology, two hybrid, pull down, enzymatic study Yuan ZQ (2005), Yuan ZQ (2005), Yuan ZQ (2005), Yuan ZQ (2005) 4
MAP3K8 2 TRAF6 0 affinity chromatography technology Chan H (2005) 1
EGFR 5 PLCG1 6 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Tvorogov D (2002), Bedrin MS (1997), Crovello CS (1998), Choi JH (2003), Jones RB (2006), Tong J (2014), Egan JE (2002), Wu D (2009), Wu D (2009) 9
MAPK14 0 CDKN1A 1 enzymatic study, affinity chromatography technology Kim GY (2002), Kim GY (2002) 2
TNK2 7 CDC37 0 affinity chromatography technology, affinity chromatography technology Huttlin EL (2017), Mahendrarajah N (2017) 2
PPP1CA 3 GSK3A 1 affinity chromatography technology St-Denis N (2016) 1
AKT1 1 VIM 0 affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study Zhu QS (2011), Zhu QS (2011), Zhu QS (2011), Zhu QS (2011) 4
RARA 5 AKT1 1 affinity chromatography technology, enzymatic study, pull down Srinivas H (2006), Srinivas H (2006), Srinivas H (2006) 3
TRAF6 0 PRKCZ 5 affinity chromatography technology Sanz L (2000) 1
PPP1CA 3 BRCA1 7 affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology Winter SL (2007), Liu Y (2002), Liu Y (2002), Liu Y (2002), Liu Y (2002), Woods NT (2012), Chen BY (2014) 7
MAP3K8 2 CHUK 5 enzymatic study, affinity chromatography technology Lin X (1999), Lin X (1999) 2
VCP 6 BAD 1 affinity chromatography technology Yu CC (2013) 1
AKT1 1 SMARCC1 5 affinity chromatography technology, enzymatic study, pull down Foster KS (2006), Foster KS (2006), Foster KS (2006) 3
PPP1CA 3 SKP2 2 affinity chromatography technology Liu X (2016) 1
APPL1 1 AR 3 affinity chromatography technology Yang L (2003) 1
CDKN1C 0 SKP2 2 affinity chromatography technology, affinity chromatography technology, enzymatic study Kamura T (2003), Calvisi DF (2009), Kamura T (2003) 3
GSK3B 1 XIAP 0 affinity chromatography technology Sun M (2009) 1
AR 3 PPP2CA 7 affinity chromatography technology Ni L (2010) 1
ILK 0 FANCI 1 affinity chromatography technology, affinity chromatography technology Ewing RM (2007), Varjosalo M (2013) 2
PRKCZ 5 HSP90AA1 7 two hybrid, affinity chromatography technology, affinity chromatography technology Bandyopadhyay S (2010), Taipale M (2012), Taipale M (2012) 3
AKT1 1 PPL 6 two hybrid, pull down, affinity chromatography technology, two hybrid Wang J (2008), van den Heuvel AP (2002), van den Heuvel AP (2002), van den Heuvel AP (2002) 4
AR 3 EP300 36 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology Dai Y (2008), Minges JT (2013), Zhong J (2014), Fu M (2000), McClurg UL (2016), Tan G (2017) 6
BRCA1 7 CDC37 0 affinity chromatography technology Ertych N (2016) 1
VCP 6 APPL1 1 affinity chromatography technology Yu CC (2013) 1
AKT1 1 CCNF 2 affinity chromatography technology, affinity chromatography technology, enzymatic study Choudhury R (2017), Choudhury R (2017), Choudhury R (2017) 3
IKBKB 1 FKBP5 0 affinity chromatography technology Li S (2011) 1
NPM1 0 FANCA 5 affinity chromatography technology Du W (2010) 1
HSPB1 2 YWHAZ 1 two hybrid Katsogiannou M (2014) 1
SMARCB1 1 BRCA1 7 biochemical, biochemical, affinity chromatography technology Bochar DA (2000), Bochar DA (2000), Fontana GA (2017) 3
FKBP5 0 CHUK 5 affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014) 2
NPM1 0 YBX1 1 affinity chromatography technology, affinity chromatography technology Park G (2010), Chen R (2013) 2
CDKN1A 1 CDKN1B 1 genetic interference, imaging technique Hsu SP (2008), Chen TC (2014) 2
HSP90AA1 7 SETDB1 3 affinity chromatography technology Taipale M (2012) 1
MAPKAPK2 1 MAPK14 0 affinity chromatography technology, protein complementation assay, two hybrid, affinity chromatography technology, pull down, x-ray crystallography, x-ray crystallography, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology Rane MJ (2001), Srivastav RK (2011), Wang J (2011), Varjosalo M (2013), Rane MJ (2001), White A (2007), ter Haar E (2007), Varjosalo M (2013), Gum RJ (1999), Gum RJ (1999), So J (2015), Huttlin EL (2015), Hein MY (2015), Chen TC (2014), Smith JA (2000), Huttlin EL (2017) 16
SKI 3 SIRT1 3 affinity chromatography technology Inoue Y (2011) 1
RAF1 3 XIAP 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, enzymatic study, imaging technique Dogan T (2008), Tian S (2006), Tian S (2006), Tian S (2006), Tian S (2006), Tian S (2006), Chen TC (2014) 7
GSK3B 1 PHLPP1 4 enzymatic study Li X (2009) 1
VHL 0 SETDB1 3 affinity chromatography technology Huttlin EL (2017) 1
CDKN1B 1 VHL 0 genetic interference Shen JP (2017) 1
SIRT6 2 AKT1 1 affinity chromatography technology, affinity chromatography technology, enzymatic study Thirumurthi U (2014), Thirumurthi U (2014), Thirumurthi U (2014) 3
MDM2 2 AKT1 1 affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique Lin HK (2002), Ogawara Y (2002), Zhou BP (2001), Zhou BP (2001), Kim CK (2011), Kim CK (2011), Zhu QS (2011), Milne D (2004), Deep G (2008), Deep G (2008), Chen TC (2014) 11
PRKDC 12 AKT1 1 enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, genetic interference Feng J (2004), Feng J (2004), Feng J (2004), Dragoi AM (2005), Dragoi AM (2005), Dragoi AM (2005), Shen JP (2017) 7
EZH2 4 SNAI1 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, biochemical Herranz N (2008), Tong ZT (2012), Tong ZT (2012), Chen J (2014), Chen J (2014) 5
DAB2IP 3 AKT1 1 affinity chromatography technology, affinity chromatography technology, enzymatic study Xie D (2009), Xie D (2009), Dai X (2014) 3
AKT1 1 IKBKB 1 affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology Vandermoere F (2005), Vandermoere F (2005), Chen TC (2014), Busch F (2012) 4
GSK3B 1 DNMT1 5 two hybrid Vinayagam A (2011) 1
PDPK1 0 ILK 0 affinity chromatography technology Persad S (2001) 1
PRKDC 12 PPP2CA 7 affinity chromatography technology Douglas P (2010) 1
TRAF6 0 MTOR 14 affinity chromatography technology, enzymatic study Linares JF (2013), Linares JF (2013) 2
APPL1 1 PRKCZ 5 imaging technique, affinity chromatography technology Song J (2016), Song J (2016) 2
MTOR 14 ILK 0 affinity chromatography technology McDonald PC (2008) 1
BRCA1 7 DNMT1 5 affinity chromatography technology Hill SJ (2014) 1
MDM2 2 FOXO4 0 enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology Brenkman AB (2008), Brenkman AB (2008), Brenkman AB (2008), Szypowska AA (2011), Szypowska AA (2011), Oteiza A (2011) 6
TRAF6 0 USP4 3 affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology Xiao N (2011), Xiao N (2011), Xiao N (2011), Xiao N (2011), Zhou F (2012), Zhou F (2012) 6
GSK3B 1 VIM 0 two hybrid Vinayagam A (2011) 1
NPM1 0 PPP2CA 7 affinity chromatography technology Chen R (2013) 1
TNK2 7 HSP90AA1 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Mahajan NP (2005), Mahajan NP (2005), Taipale M (2012), Gao B (2013), Mahendrarajah N (2017), Mahendrarajah N (2017), Mahendrarajah N (2017) 7
HSP90AA1 7 TERT 7 affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down Haendeler J (2003), Kawauchi K (2005), Holt SE (1999), Lee JH (2010), Lee JH (2010), Forsythe HL (2001) 6
EGFR 5 YBX1 1 affinity chromatography technology Yao Z (2017) 1
APPL1 1 AKT1 1 affinity chromatography technology, two hybrid, imaging technique Yang L (2003), Grossmann A (2015), Chen TC (2014) 3
RARA 5 SIRT1 3 affinity chromatography technology, pull down Kang MR (2010), Kang MR (2010) 2
EP300 36 SIRT1 3 affinity chromatography technology, affinity chromatography technology Bouras T (2005), Bourguignon LY (2009) 2
AKT1 1 VHL 0 affinity chromatography technology, affinity chromatography technology, pull down, pull down, unspecified method Guo J (2016), Guo J (2016), Guo J (2016), Guo J (2016), Guo J (2016) 5
MAPKAP1 0 MTOR 14 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Yang Q (2006), Jacinto E (2006), Jacinto E (2006), Pearce LR (2007), Oh WJ (2010), Yang Q (2006), Murata H (2011), Koike-Kumagai M (2009), Koike-Kumagai M (2009), Martin J (2008), Thedieck K (2007), Thedieck K (2007), Hong F (2008), Facchinetti V (2008), Facchinetti V (2008), Glidden EJ (2012), Vander Haar E (2007) 17
AKT1 1 PLCG1 6 affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study Wang Y (2006), Wang Y (2006), Wang Y (2006), Wang Y (2006) 4
SKI 3 PRKDC 12 affinity chromatography technology Rashidian J (2015) 1
AKTIP 3 EGFR 5 affinity chromatography technology, affinity chromatography technology Muthusami S (2015), Subramanian PD (2016) 2
BCL10 0 PPP2CA 7 affinity chromatography technology Eitelhuber AC (2011) 1
GSK3B 1 FOXO1 2 imaging technique Chen TC (2014) 1
MDM2 2 HSP90AA1 7 affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, biochemical, unspecified method, affinity chromatography technology Lu TL (2010), Burch L (2004), Burch L (2004), Burch L (2004), Burch L (2004), Burch LR (2004), Okoro DR (2013) 7
PIK3R1 6 VHL 0 genetic interference Shen JP (2017) 1
STK4 1 CDC37 0 affinity chromatography technology Hauri S (2013) 1
BRAF 12 VHL 0 genetic interference Shen JP (2017) 1
HSP90AA1 7 CLK2 2 affinity chromatography technology Taipale M (2012) 1
MTOR 14 RICTOR 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Jacinto E (2004), Jacinto E (2004), Sarbassov DD (2004), Sarbassov DD (2004), Sarbassov DD (2004), Frias MA (2006), Jacinto E (2006), Yang Q (2006), Frias MA (2006), Sarbassov DD (2006), Sarbassov DD (2005), Yang Q (2006), Kaizuka T (2010), Pearce LR (2007), Oh WJ (2010), Oh WJ (2010), Agrawal P (2012), Guo Z (2012), Sarbassov DD (2006), Sancak Y (2007), Yang Q (2006), Jacinto E (2006), Jacinto E (2006), Rosner M (2010), Ikenoue T (2008), Ikenoue T (2008), Murata H (2011), Murata H (2011), Koike-Kumagai M (2009), Koike-Kumagai M (2009), Woods NT (2012), Hussain S (2013), Peterson TR (2009), Peterson TR (2009), Su WC (2009), Hernandez-Negrete I (2007), Ramirez-Rangel I (2011), Martin J (2008), Martin J (2008), Martin J (2008), Thedieck K (2007), Thedieck K (2007), Thedieck K (2007), McDonald PC (2008), McDonald PC (2008), Hong F (2008), Hong F (2008), Facchinetti V (2008), Toschi A (2009), Zhang F (2010), Chen CH (2011), Chen CH (2011), Xu Y (2013), Xu Y (2013), Glidden EJ (2012), Glidden EJ (2012), Vander Haar E (2007), Koo J (2015), Thedieck K (2007) 59
RARA 5 EP300 36 affinity chromatography technology, affinity chromatography technology Subbaramaiah K (2002), Reineke EL (2007) 2
AKT1 1 NF2 1 affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe Tang X (2007), Tang X (2007), Tang X (2007), Tang X (2007), Laulajainen M (2011), Laulajainen M (2011), Laulajainen M (2011), Laulajainen M (2011), Ivanov AA (2017) 9
SMARCB1 1 SMARCC1 5 biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical Sif S (2001), Wang W (1996), Ryme J (2009), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Foster KS (2006), Foster KS (2006), Medjkane S (2004), Sif S (1998), Dallas PB (1998), Bartlett C (2011), Havugimana PC (2012), Wan C (2015) 15
AKT1 1 CHUK 5 affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology Ozes ON (1999), Ozes ON (1999), Romashkova JA (1999), Lu Y (2005), Chen TC (2014), Takada Y (2005), Koul D (2001) 7
AKT1 1 SRPK2 1 enzymatic study, affinity chromatography technology, pull down, imaging technique Jang SW (2009), Jang SW (2009), Jang SW (2009), Jang SW (2009) 4
TRAF6 0 VCP 6 affinity chromatography technology Ewing RM (2007) 1
RARA 5 MDM2 2 affinity chromatography technology, affinity chromatography technology, enzymatic study Ying M (2016), Ying M (2016), Ying M (2016) 3
IKBKB 1 MTOR 14 affinity chromatography technology, affinity chromatography technology, biochemical Dan HC (2008), Dan HC (2008), Dan HC (2008) 3
AKT1 1 USP4 3 pull down, affinity chromatography technology, enzymatic study Zhang L (2012), Zhang L (2012), Zhang L (2012) 3
RAF1 3 PRKCZ 5 affinity chromatography technology, affinity chromatography technology, pull down Van Der Hoeven PC (2000), Van Der Hoeven PC (2000), Van Der Hoeven PC (2000) 3
EZH2 4 SIRT1 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study Kuzmichev A (2005), Kuzmichev A (2005), OHagan HM (2011), Wan J (2015), Wan J (2015), Wan J (2015) 6
RAF1 3 STK3 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology Kilili GK (2010), Matallanas D (2007), ONeill E (2004), ONeill E (2004), ONeill E (2004), ONeill E (2004), Romano D (2010), Romano D (2010) 8
SKP2 2 VHL 0 affinity chromatography technology, affinity chromatography technology, pull down Roe JS (2011), Roe JS (2011), Roe JS (2011) 3
IKBKB 1 HSP90AA1 7 affinity chromatography technology Xue J (2010) 1
TSC2 17 GSK3B 1 affinity chromatography technology, enzymatic study, affinity chromatography technology Mak BC (2003), Inoki K (2006), Mak BC (2003) 3
RICTOR 4 AKT1 1 enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, enzymatic study Sarbassov DD (2006), Sarbassov DD (2005), Ikenoue T (2008), Murata H (2011), Woods NT (2012), Kim EK (2011), Chen CH (2011), Garcia-Martinez JM (2009), Chen TC (2014), Pitre A (2012) 10
IKBKB 1 CDC37 0 biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Chen G (2002), Chen G (2002), Li S (2011), Taipale M (2014), Taipale M (2014), Hein MY (2015) 6
MTOR 14 GNB1 4 two hybrid, affinity chromatography technology, affinity chromatography technology Robles-Molina E (2014), Robles-Molina E (2014), Robles-Molina E (2014) 3
HSP90AA1 7 AR 3 affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Veldscholte J (1992), Nemoto T (1992), Zoubeidi A (2007), DaSilva J (2009), Chymkowitch P (2011), Gibbs A (2009), Wolf SS (2007), Luo J (2015), Kwegyir-Afful AK (2015), Ni L (2010), McClurg UL (2016) 11
TRAF6 0 AKT1 1 enzymatic study, affinity chromatography technology, affinity chromatography technology Yang WL (2009), Mitra S (2011), Mitra S (2011) 3
CDKN1A 1 NPM1 0 affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology Xiao J (2009), Xiao J (2009), Xiao J (2009), Xiao J (2009), Li J (2005) 5
XIAP 0 BCL10 0 affinity chromatography technology Hu S (2006) 1
NPM1 0 YWHAZ 1 affinity chromatography technology Chen R (2013) 1
TSC1 4 VHL 0 genetic interference Shen JP (2017) 1
PRKDC 12 IKBKB 1 enzymatic study Liu L (1998) 1
AR 3 FOXO1 2 affinity chromatography technology, two hybrid, far western blotting Li P (2003), Li P (2003), Li P (2003) 3
NPM1 0 PLCG1 6 pull down, affinity chromatography technology Bai RY (1998), Bai RY (1998) 2
AKT1 1 GNB1 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Klein JB (2005), Xiong Y (2009), Xiong Y (2009) 3
FOXO1 2 MDM2 2 affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology Fu W (2009), Fu W (2009), Fu W (2009), Fu W (2009), Jang H (2016) 5
EP300 36 CHUK 5 imaging technique Hao L (2010) 1
BRCA1 7 MTOR 14 affinity chromatography technology Woods NT (2012) 1
AKT1 1 AKTIP 3 affinity chromatography technology, pull down, pull down Remy I (2004), Remy I (2004), Remy I (2004) 3
FOXO4 0 SIRT1 3 affinity chromatography technology van der Horst A (2004) 1
STK3 1 STK4 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, fluorescent resonance energy transfe Behrends C (2010), Behrends C (2010), Couzens AL (2013), Couzens AL (2013), Couzens AL (2013), Couzens AL (2013), Varjosalo M (2013), Varjosalo M (2013), Hauri S (2013), Hauri S (2013), Wan C (2015), Ivanov AA (2017) 12
SKI 3 AKT1 1 affinity chromatography technology, affinity chromatography technology, enzymatic study Band AM (2009), Band AM (2009), Band AM (2009) 3
BRAF 12 FKBP5 0 affinity chromatography technology Eisenhardt AE (2016) 1
PRKDC 12 GSK3A 1 enzymatic study Dragoi AM (2005) 1
AKTIP 3 TSC1 4 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
RAF1 3 TERT 7 fluorescent resonance energy transfe Ivanov AA (2017) 1
BRAF 12 PPP1CA 3 affinity chromatography technology Eisenhardt AE (2016) 1
HSP90AA1 7 MAP3K8 2 affinity chromatography technology, affinity chromatography technology Taipale M (2012), Taipale M (2012) 2
AKT1 1 MAP2K4 3 affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology Park HS (2002), Park HS (2002), Park HS (2002), Song JJ (2005), Song JJ (2005) 5
PHLPP1 4 AKT1 1 affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology Mistafa O (2010), Gao T (2005), Gao T (2005), Zhang X (2016) 4
AKT1 1 MTOR 14 pull down, unspecified method, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, imaging technique, enzymatic study, imaging technique Sekulic A (2000), Cheng SW (2004), Oh WJ (2010), Sarbassov DD (2005), Ikenoue T (2008), Murata H (2011), Martin J (2008), Facchinetti V (2008), Facchinetti V (2008), Chen CH (2011), Xu Y (2013), Glidden EJ (2012), Chen TC (2014), Pitre A (2012), Moon HE (2015) 15
FKBP5 0 AKT1 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Mistafa O (2010), Luo K (2017), Luo K (2017) 3
MAP2K4 3 MAPK14 0 enzymatic study, affinity chromatography technology, pull down Deacon K (1997), Xia Y (1998), Xia Y (1998) 3
AR 3 FKBP5 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Schuelke JP (2010), Ni L (2010), Luo K (2017) 3
NF2 1 AGAP2 14 pull down Tang X (2007) 1
TSC2 17 TSC1 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Dan HC (2002), Hodges AK (2001), Aicher LD (2001), van Slegtenhorst M (1998), Nellist M (2002), Li Y (2004), Mak BC (2003), van Slegtenhorst M (1998), van Slegtenhorst M (1998), Ma L (2005), Cai SL (2006), Cao Y (2006), Ma L (2005), Inoki K (2003), Nellist M (2005), Goncharova EA (2006), Astrinidis A (2006), Cao Y (2006), Astrinidis A (2003), Hodges AK (2001), Hodges AK (2001), Nellist M (2001), Aicher LD (2001), Murthy V (2000), van Slegtenhorst M (1998), Dan HC (2002), Miloloza A (2000), Nakashima A (2007), Nakashima A (2007), Benvenuto G (2000), Chong-Kopera H (2006), York B (2005), Vega-Rubin-de-Celis S (2010), Vega-Rubin-de-Celis S (2010), Lin Y (2011), Cloutier P (2017), Cloutier P (2017) 37
AKT1 1 VCP 6 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology Vandermoere F (2006), Vandermoere F (2006), Vandermoere F (2006), Klein JB (2005), Klein JB (2005), Klein JB (2005), Yu CC (2013), Yu CC (2013) 8
AKT1 1 BRAF 12 affinity chromatography technology, affinity chromatography technology, enzymatic study, imaging technique, fluorescent resonance energy transfe Guan KL (2000), Guan KL (2000), Guan KL (2000), Chen TC (2014), Ivanov AA (2017) 5
TSC1 4 YWHAZ 1 two hybrid Nellist M (2002) 1
AKT1 1 ALYREF 0 enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down Okada M (2008), Okada M (2008), Okada M (2008), Okada M (2008) 4
AKT1 1 MAPKAPK2 1 affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, imaging technique Rane MJ (2001), Rane MJ (2001), Rane MJ (2001), Rane MJ (2001), Wu R (2007), Wu R (2007), Chen TC (2014) 7
CHUK 5 BCL10 0 affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down Poyet JL (2001), Poyet JL (2001), Marinis JM (2012), Zhou H (2004) 4
AKT1 1 STK4 1 enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down Yuan Z (2010), Yuan Z (2010), Yuan Z (2010), Cinar B (2007), Cinar B (2007), Cinar B (2007), Cinar B (2007), Cinar B (2007) 8
MAPK14 0 EP300 36 pull down, enzymatic study, affinity chromatography technology Pillai VB (2011), Pillai VB (2011), Saha RN (2007) 3
GNB1 4 RICTOR 4 affinity chromatography technology, affinity chromatography technology Robles-Molina E (2014), Robles-Molina E (2014) 2
BRCA1 7 IMPDH2 3 affinity chromatography technology Ertych N (2016) 1
VCP 6 CDC37 0 affinity chromatography technology Yu CC (2013) 1
MAPK14 0 RICTOR 4 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
VCP 6 AR 3 affinity chromatography technology, pull down Fujita K (2013), Fujita K (2013) 2
RAF1 3 HSP90AA1 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Stancato LF (1993), Dogan T (2008), Mollapour M (2010), Du J (2006), Maloney A (2007), Fiskus W (2007), Giommarelli C (2010), Arlander SJ (2006), ONeill E (2004), Taipale M (2012), Zhu J (2005), Schneider C (1996), Mollapour M (2014), Atabakhsh E (2012), Mitra S (2016) 15
MDM2 2 SIRT6 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Thirumurthi U (2014), Thirumurthi U (2014), Nihira NT (2017), Huttlin EL (2017) 4
ILK 0 HSPB1 2 affinity chromatography technology, affinity chromatography technology Ewing RM (2007), So J (2015) 2
AKT1 1 NPM1 0 pull down, pull down, affinity chromatography technology, affinity chromatography technology Lee SB (2008), Lee SB (2008), Lee SB (2008), Lee SB (2008) 4
MAPK14 0 IKBKB 1 affinity chromatography technology, affinity chromatography technology Tsuchiya Y (2010), Tsuchiya Y (2010) 2
SIRT1 3 PIK3R1 6 affinity chromatography technology Froejdoe S (2011) 1
EGFR 5 CDC37 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Lavictoire SJ (2003), Foerster S (2013), Li J (2013), Li J (2013) 4
SIRT1 3 NOS3 7 affinity chromatography technology Chen Z (2010) 1
RAF1 3 BAD 1 enzymatic study, enzymatic study, imaging technique Jin S (2005), Polzien L (2009), Chen TC (2014) 3
PHLPP1 4 FANCI 1 affinity chromatography technology, affinity chromatography technology Zhang X (2016), Zhang X (2016) 2
SIRT6 2 NPM1 0 affinity chromatography technology Simeoni F (2013) 1
SIRT1 3 ARRB2 5 affinity chromatography technology Armour SM (2013) 1
SIRT1 3 AKT1 1 affinity chromatography technology, affinity chromatography technology, enzymatic study Sundaresan NR (2011), Sundaresan NR (2011), Sundaresan NR (2011) 3
SIRT1 3 AR 3 affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study Fu M (2006), Fu M (2006), Fu M (2006), Fu M (2006) 4
HSP90AA1 7 ARNT 1 affinity chromatography technology Isaacs JS (2004) 1
VCP 6 FANCI 1 affinity chromatography technology Yu CC (2013) 1
EP300 36 VHL 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Roe JS (2006), Roe JS (2011), Roe JS (2011), Ji W (2014), Chen K (2015) 5
TSC2 17 FOXO1 2 affinity chromatography technology, pull down, imaging technique, affinity chromatography technology Cao Y (2006), Cao Y (2006), Cao Y (2006), Cao Y (2006) 4
EP300 36 NPM1 0 enzymatic study Swaminathan V (2005) 1
SMARCB1 1 VHL 0 genetic interference Shen JP (2017) 1
PHLPP1 4 FKBP5 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), St-Denis N (2016), Luo K (2017), Luo K (2017) 4
MTOR 14 EP300 36 enzymatic study Wan W (2017) 1
GSK3B 1 YBX1 1 enzymatic study Coles LS (2005) 1
AR 3 MDM2 2 affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Zoubeidi A (2007), Gaughan L (2005), Gaughan L (2005), Chymkowitch P (2011), Chymkowitch P (2011), Liu T (2012), Liu T (2012), Deep G (2008), Deep G (2008), Lin HK (2002), Lin HK (2002), Zhang A (2015), Kwegyir-Afful AK (2015), McClurg UL (2016), McClurg UL (2016), Liao Y (2017), Steely AM (2017), Zhai W (2016) 18
PIK3CA 8 EGFR 5 fluorescent resonance energy transfe Ivanov AA (2017) 1
FKBP5 0 HSP90AA1 7 affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology Nair SC (1997), Nair SC (1997), Li J (2011), Schuelke JP (2010), Gano JJ (2010), Skarra DV (2011), Horibe T (2011), Kristensen AR (2012), Taipale M (2014), Taipale M (2014), Graumann K (2000), Ni L (2010), Luo K (2017) 13
PPP2CA 7 IKBKB 1 affinity chromatography technology Kray AE (2005) 1
AKT1 1 IMPDH2 3 two hybrid, pull down, affinity chromatography technology Ingley E (2000), Ingley E (2000), Ingley E (2000) 3
VCP 6 HSPB1 2 affinity chromatography technology Yu CC (2013) 1
AKT1 1 ARNT 1 affinity chromatography technology, affinity chromatography technology, enzymatic study, fluorescent resonance energy transfe Li YM (2005), Li YM (2005), Li YM (2005), Ivanov AA (2017) 4
AKT1 1 YWHAZ 1 affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology Powell DW (2002), Powell DW (2002), Powell DW (2002), Klein JB (2005) 4
PIK3CA 8 AKT1 1 affinity chromatography technology, protein complementation assay, affinity chromatography technology, enzymatic study Mitra S (2011), Miao B (2010), Xiong Y (2009), Akil H (2015) 4
NEDD4 2 AKT1 1 enzymatic study, enzymatic study, affinity chromatography technology Persaud A (2009), Fan CD (2013), Fan CD (2013) 3
HSP90AA1 7 CDC37 0 x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology Roe SM (2004), Silverstein AM (1998), Mollapour M (2010), Basso AD (2002), Tsutsumi S (2012), De Nardo D (2005), Sarkar S (2012), Gano JJ (2010), Taipale M (2012), Skarra DV (2011), Zhang H (2004), Taipale M (2014), Taipale M (2014), Mollapour M (2014), Hein MY (2015), Hein MY (2015), Li J (2013), Woodford MR (2016), Shao J (2003), Scholz GM (2001), Sun L (2012), Sun L (2012), Woodford MR (2016), Synoradzki K (2015) 24
TRAF6 0 YBX1 1 two hybrid Wang J (2011) 1
EP300 36 ARNT 1 affinity chromatography technology Tohkin M (2000) 1
IKBKB 1 CHUK 5 affinity chromatography technology, biochemical, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology Zandi E (1997), Chen G (2002), Otsuki T (2002), May MJ (2000), May MJ (2000), Woronicz JD (1997), Woronicz JD (1997), Deng L (2000), Yeung KC (2001), Mercurio F (1997), Mercurio F (1997), Rothwarf DM (1998), Wu ZH (2010), Li S (2011), Li S (2011), May MJ (2002), Heilker R (1999), Leotoing L (2011), McKenzie FR (2000), Zandi E (1998), Lee DF (2007), Li XH (2001), Yeh PY (2011), Yeh PY (2011), Stehlik C (2002), Li Q (2006), So J (2015), Chen TC (2014), Karim ZA (2015), Huttlin EL (2017) 30
VCP 6 PPP2CA 7 affinity chromatography technology, affinity chromatography technology Ohama T (2010), Yakovlev VA (2013) 2
NF2 1 TSC1 4 fluorescent resonance energy transfe Ivanov AA (2017) 1
MAPK14 0 NF2 1 fluorescent resonance energy transfe Ivanov AA (2017) 1
PIK3R1 6 EP300 36 affinity chromatography technology Song L (2011) 1
EGFR 5 AR 3 affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique Bonaccorsi L (2004), Bonaccorsi L (2004), Bonaccorsi L (2004), Bonaccorsi L (2004) 4
EZH2 4 RARA 5 affinity chromatography technology Villa R (2007) 1
UBE2S 2 AKT1 1 affinity chromatography technology, affinity chromatography technology, enzymatic study Hu L (2017), Hu L (2017), Hu L (2017) 3
EGFR 5 HSPB1 2 affinity chromatography technology Li J (2013) 1
EZH2 4 YBX1 1 affinity chromatography technology Cao Q (2014) 1
VCP 6 MDM2 2 affinity chromatography technology, affinity chromatography technology Yu CC (2013), Okoro DR (2013) 2
BRCA1 7 YWHAZ 1 affinity chromatography technology, affinity chromatography technology Woods NT (2012), Ertych N (2016) 2
IKBKB 1 TSC1 4 affinity chromatography technology, pull down Lee DF (2007), Lee DF (2007) 2
VCP 6 YWHAZ 1 affinity chromatography technology, two hybrid Yu CC (2013), Wang J (2011) 2
FOXO1 2 YWHAZ 1 affinity chromatography technology, fluorescent resonance energy transfe Rena G (2001), Ivanov AA (2017) 2
BRCA1 7 PPP2CA 7 affinity chromatography technology Woods NT (2012) 1
NPM1 0 PIK3R1 6 affinity chromatography technology Crockett DK (2004) 1
TRAF6 0 IKBKB 1 affinity chromatography technology Bidere N (2006) 1
ITPR1 25 VCP 6 affinity chromatography technology Pearce MM (2009) 1
CDKN1A 1 VIM 0 two hybrid Vinayagam A (2011) 1
VCP 6 CDKN1A 1 affinity chromatography technology Yu CC (2013) 1
VHL 0 JADE1 6 two hybrid, affinity chromatography technology, affinity chromatography technology, pull down Zhou MI (2002), Zhou MI (2002), Zhou MI (2004), Zhou MI (2004) 4
APPL1 1 PIK3CA 8 imaging technique Chen TC (2014) 1
AKT1 1 TBK1 1 affinity chromatography technology, affinity chromatography technology, enzymatic study Joung SM (2011), Joung SM (2011), Joung SM (2011) 3
ARRB2 5 RAF1 3 affinity chromatography technology Luttrell LM (2001) 1
HSP90AA1 7 CDKN1A 1 affinity chromatography technology Jascur T (2005) 1
EGFR 5 TBK1 1 affinity chromatography technology Tong J (2014) 1
USP4 3 IKBKB 1 affinity chromatography technology Fan YH (2011) 1
BRCA1 7 YBX1 1 affinity chromatography technology, affinity chromatography technology Woods NT (2012), Ertych N (2016) 2
NEDD4 2 EGFR 5 enzymatic study, pull down Persaud A (2009), Persaud A (2009) 2
FOXO1 2 SKP2 2 affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Huang H (2005), Huang H (2005), Huang H (2005), Calvisi DF (2009), Park J (2018), Park J (2018) 6
EGFR 5 PRKDC 12 affinity chromatography technology Foerster S (2013) 1
BRCA1 7 AKT1 1 pull down, affinity chromatography technology, pull down, enzymatic study, pull down Altiok S (1999), Xiang T (2008), Xiang T (2008), Xiang T (2008), Xiang T (2011) 5
VHL 0 PRKCZ 5 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Okuda H (1999), Okuda H (1999), Schermer B (2006) 3
MAPKAPK2 1 MDM2 2 enzymatic study Weber HO (2005) 1
EGFR 5 MTOR 14 affinity chromatography technology Foerster S (2013) 1
CDKN1B 1 TSC1 4 affinity chromatography technology Rosner M (2004) 1
PRKCZ 5 AKT1 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology Doornbos RP (1999), Wang J (2008), Wang J (2008), Joshi J (2008), Joshi J (2008) 5
BRCA1 7 FANCA 5 two hybrid, pull down, affinity chromatography technology, affinity chromatography technology Folias A (2002), Folias A (2002), Folias A (2002), Suhasini AN (2011) 4
EZH2 4 BRCA1 7 affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology Wang L (2013), Wang L (2013), Wang L (2013), Wang L (2013), Gong C (2015) 5
EP300 36 MDM2 2 pull down, affinity chromatography technology, biochemical, pull down, pull down, enzymatic study, affinity chromatography technology, biochemical, enzymatic study Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Matt T (2004), Wang X (2004), Gillotin S (2010), Kobet E (2000), Nihira NT (2017) 9
TNK2 7 AKT1 1 affinity chromatography technology, pull down, affinity chromatography technology Zhang J (2015), Zhang J (2015), Hu F (2016) 3
RAF1 3 PPP2CA 7 affinity chromatography technology Rajalingam K (2005) 1
NEDD4 2 IMPDH2 3 biochemical Wan C (2015) 1
RARA 5 SKI 3 affinity chromatography technology, affinity chromatography technology, imaging technique Zhao HL (2009), Ritter M (2006), Ritter M (2006) 3
EZH2 4 AR 3 affinity chromatography technology Cao Q (2014) 1
NPM1 0 VCP 6 affinity chromatography technology Chen R (2013) 1
ARRB2 5 VIM 0 affinity chromatography technology Xiao K (2007) 1
ITPR1 25 AKT1 1 affinity chromatography technology, affinity chromatography technology, protein complementation assay, enzymatic study Szado T (2008), Szado T (2008), Szado T (2008), Szado T (2008) 4
AR 3 SMARCC1 5 affinity chromatography technology, bioid Wang Q (2004), Lempiaeinen JK (2017) 2
YWHAZ 1 MDM2 2 affinity chromatography technology Zhang B (2017) 1
NPM1 0 SIRT1 3 affinity chromatography technology Park G (2010) 1