PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
COPS3	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Min KW (2005), Enchev RI (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	9
5430	0	ERCC4	2	affinity chromatography technology	Fousteri M (2006)	1
HIST1H3A	3	DDB1	6	affinity chromatography technology, pull down	Higa LA (2006), Higa LA (2006)	2
CAND1	2	UBC	7	affinity chromatography technology	Bennett EJ (2010)	1
BRCA1	7	HNRNPU	12	affinity chromatography technology	Ertych N (2016)	1
PARP1	3	HIST1H3A	3	enzymatic study	Bonfiglio JJ (2017)	1
XAB2	0	5430	0	affinity chromatography technology, affinity chromatography technology	Nakatsu Y (2000), Fousteri M (2006)	2
BRCA1	7	CAND1	2	affinity chromatography technology	Ertych N (2016)	1
TP53	0	RPA1	0	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Romanova LY (2004), Romanova LY (2004), Riva F (2001), Glanzer JG (2013)	4
TP53	0	COPS4	0	affinity chromatography technology	Bhansali M (2014)	1
DDB1	6	COPS6	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Emberley ED (2012), Bennett EJ (2010), Olma MH (2009)	5
MDM2	2	ERCC8	1	affinity chromatography technology	Latini P (2011)	1
KAT2B	2	HIST1H4A	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study	Brackertz M (2006), Seo SB (2002), Ito K (2000), Kim JH (2002), Wong K (2005), Hoffmann A (2008), Shen M (2013), Zheng X (2013), Zheng X (2013), Yamaguchi Y (2004)	10
ERCC6	6	CUL4A	2	affinity chromatography technology	Latini P (2011)	1
USP7	14	COPS6	0	biochemical	Kristensen AR (2012)	1
USP7	14	HIST2H2AC	1	affinity chromatography technology, enzymatic study	Lecona E (2015), Yu M (2016)	2
MDM2	2	KAT2B	2	pull down, affinity chromatography technology, genetic interference, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Jin Y (2002), Jin Y (2002), Jin Y (2002), Jin Y (2004), Jin Y (2004), Jung CR (2010), Morgan JE (2017)	7
BRCA1	7	5430	0	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Krum SA (2003), Scully R (1997), Scully R (1997), Chiba N (2001), Chiba N (2001), Krum SA (2003), Starita LM (2005), Woods NT (2012), Bennett CB (2008), Hill SJ (2014), Winton CE (2016)	11
HIST1H2BB	3	ERCC6	6	affinity chromatography technology, affinity chromatography technology, far western blotting	Citterio E (2000), Citterio E (2000), Citterio E (2000)	3
CUL4A	2	MDM2	2	affinity chromatography technology, affinity chromatography technology	Banks D (2006), Latini P (2011)	2
COPS3	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Kristensen AR (2012), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
HIST1H3A	3	HIST1H2BB	3	affinity chromatography technology	Klement K (2014)	1
BAZ1B	5	ERCC6	6	affinity chromatography technology, affinity chromatography technology	Cavellan E (2006), Cavellan E (2006)	2
CAND1	2	HNRNPU	12	affinity chromatography technology	Bennett EJ (2010)	1
XPA	1	RPA1	0	two hybrid, pull down, affinity chromatography technology	Li L (1995), Li L (1995), Lange SS (2009)	3
ERCC8	1	VCP	6	affinity chromatography technology	He J (2016)	1
VCP	6	CUL7	4	affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Hanson D (2014)	2
CUL4B	8	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Jin J (2006), Wang H (2006), Higa LA (2006), Higa LA (2006), Kawajiri K (2009), Bennett EJ (2010), Havugimana PC (2012), Ji Q (2014), Wan C (2015), Hein MY (2015), Mo Y (2017), Mo Y (2017), Yang Y (2015), Yang Y (2015), Yang Y (2015), Higa LA (2006), Higa LA (2006), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007)	23
CUL4A	2	TP53	0	affinity chromatography technology	Banks D (2006)	1
SPTA1	10	ERCC4	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sridharan D (2003), Sridharan DM (2006), Sridharan DM (2006)	3
HIST1H3A	3	HIST1H2AB	0	affinity chromatography technology	Tropberger P (2013)	1
NOP56	0	HNRNPU	12	affinity chromatography technology, affinity chromatography technology	Hayano T (2003), Hein MY (2015)	2
UBC	7	COPS4	0	affinity chromatography technology	Matsumoto M (2005)	1
TP53	0	BAX	3	imaging technique, affinity chromatography technology, pull down	Chen TC (2014), Kim EM (2014), Kim EM (2014)	3
COPS6	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Kristensen AR (2012), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
UBC	7	VCP	6	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down	Matsumoto M (2005), Zhong X (2006), Dai RM (2001), Bish RA (2007), Lim JJ (2016), Zhang X (2017)	6
DDB1	6	UBC	7	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Matsumoto M (2005)	2
ERCC6	6	OGG1	0	affinity chromatography technology	Kamenisch Y (2010)	1
BRCA1	7	25885	0	affinity chromatography technology	Johnston R (2016)	1
ERCC6	6	RPA1	0	affinity chromatography technology	Fousteri M (2006)	1
ERCC8	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Olma MH (2009)	3
BRCA1	7	RPL10	3	affinity chromatography technology	Ertych N (2016)	1
MDM2	2	UBC	7	pull down, enzymatic study, enzymatic study	Higashitsuji H (2005), Luo J (2013), Poyurovsky MV (2007)	3
SPTA1	10	ERCC3	3	affinity chromatography technology, affinity chromatography technology	Sridharan DM (2006), Sridharan DM (2006)	2
CUL7	4	DDB1	6	affinity chromatography technology	Hanson D (2014)	1
TP53	0	UBC	7	affinity chromatography technology, affinity chromatography technology	Ayroldi E (2014), Ke JY (2014)	2
TP53	0	ERCC6	6	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Wang XW (1995), Yu A (2000), Yu A (2000), Latini P (2011), Latini P (2011)	5
CAND1	2	RPL10	3	affinity chromatography technology	Bennett EJ (2010)	1
ERCC6	6	USP7	14	affinity chromatography technology	Latini P (2011)	1
DDB1	6	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Angers S (2006), Jin J (2006), Min KW (2005), Emberley ED (2012), Olma MH (2009)	5
HIST2H2AC	1	HIST1H3A	3	pull down, pull down, pull down	Hoffmann A (1996), Hoffmann A (1996), Boenisch C (2012)	3
COPS6	0	COPS4	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sharon M (2009), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	14
HIST1H4A	0	HIST1H2BB	3	affinity chromatography technology	Klement K (2014)	1
CUL7	4	HNRNPU	12	affinity chromatography technology, affinity chromatography technology	Hanson D (2014), Hanson D (2014)	2
HIST1H4A	0	ERCC6	6	affinity chromatography technology, affinity chromatography technology, far western blotting	Citterio E (2000), Citterio E (2000), Citterio E (2000)	3
HIST1H4A	0	HDAC1	4	pull down, pull down, affinity chromatography technology	Shiio Y (2003), Li X (2014), Hein MY (2015)	3
XAB2	0	ERCC8	1	affinity chromatography technology, pull down	Nakatsu Y (2000), Nakatsu Y (2000)	2
HIST2H2AC	1	UBC	7	pull down, pull down	Long L (2014), Zhang X (2017)	2
BRCA1	7	HIST1H2AB	0	enzymatic study, enzymatic study	Kalb R (2014), McGinty RK (2014)	2
CAND1	2	5430	0	affinity chromatography technology	Bennett EJ (2010)	1
KAT2B	2	HIST1H2AB	0	enzymatic study, enzymatic study	Seo SB (2002), Avvakumov N (2003)	2
ERCC8	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down	Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Fei J (2012), Jin J (2006), He J (2016), Groisman R (2006), Groisman R (2006)	8
RPL10	3	BAZ1B	5	affinity chromatography technology	Hein MY (2015)	1
SPTA1	10	ERCC5	0	affinity chromatography technology	Sridharan DM (2006)	1
CUL4A	2	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Angers S (2006), Hu J (2004), Chua YS (2011), Tron AE (2012), Zheng J (2002), He YJ (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Gastaldello S (2012), Liu J (2002), Liu J (2002), Olma MH (2009), Olma MH (2009), Yang Y (2016), Yang Y (2016)	18
COPS6	0	POLD1	5	affinity chromatography technology	Bennett EJ (2010)	1
RNF11	0	USP7	14	affinity chromatography technology	Poulsen SL (2013)	1
HIST1H3A	3	ERCC6	6	affinity chromatography technology, affinity chromatography technology, far western blotting	Citterio E (2000), Citterio E (2000), Citterio E (2000)	3
ERCC6	6	ERCC4	2	affinity chromatography technology	Anindya R (2010)	1
DDB1	6	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Ji Q (2014), Ji Q (2014), Zhao R (2014), Romani B (2016)	4
KAT2B	2	HNRNPU	12	affinity chromatography technology, pull down, affinity chromatography technology	Obrdlik A (2008), Obrdlik A (2008), Obrdlik A (2008)	3
PCNA	0	BAZ1B	5	pull down	Poot RA (2004)	1
HIST1H3A	3	CUL4A	2	affinity chromatography technology, pull down	Higa LA (2006), Higa LA (2006)	2
TP53	0	ERCC8	1	affinity chromatography technology, affinity chromatography technology	Latini P (2011), Latini P (2011)	2
MDM2	2	CUL4B	8	affinity chromatography technology	Latini P (2011)	1
MDM2	2	DDB1	6	affinity chromatography technology, affinity chromatography technology	Latini P (2011), Jacob AG (2014)	2
MPHOSPH8	1	ERCC6	6	affinity chromatography technology	Hein MY (2015)	1
BRCA1	7	PCNA	0	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
ERCC6	6	SSBP1	0	affinity chromatography technology	Kamenisch Y (2010)	1
VCP	6	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Yu CC (2013), Fogeron ML (2013)	3
ERCC6	6	PARP1	3	pull down, affinity chromatography technology, enzymatic study	Thorslund T (2005), Thorslund T (2005), Thorslund T (2005)	3
CUL4A	2	USP7	14	affinity chromatography technology	Bennett EJ (2010)	1
MDM2	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, protein complementation assay, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, unspecified method, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, biochemical, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, protein complementation assay, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, imaging technique, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, pull down, unspecified method, fluorescent resonance energy transfe, two hybrid, pull down	Li M (2003), Latonen L (2001), Zhang Y (2003), Zhang Y (2003), Kurki S (2003), Kurki S (2003), Freeman DJ (2003), Ito A (2002), Ito A (2002), Grossman SR (1998), Fang S (2000), Liu G (2000), Zhang Y (1998), Zhang Y (1998), Chen J (1993), Thut CJ (1997), Leung KM (2002), Wawrzynow B (2009), Ochocka AM (2009), Chen D (2009), Hedstroem E (2009), Brenkman AB (2008), Qiu W (2008), Qiu W (2008), Zhang Z (2008), Muller P (2008), Colaluca IN (2008), Colaluca IN (2008), Colaluca IN (2008), Tang Y (2008), Tang Y (2008), Lu X (2007), Lukashchuk N (2007), Lukashchuk N (2007), Lee JH (2007), Carter S (2007), Sasaki M (2007), Brooks CL (2007), Li L (2007), Becker K (2007), Zhao BX (2006), Zhao BX (2006), Abida WM (2007), Yang WH (2006), Ma J (2006), Wallace M (2006), Shimizu H (2006), Andrews P (2006), Yang J (2009), Zhu Z (2009), Wang C (2005), Higashitsuji H (2005), Higashitsuji H (2005), Yan C (2005), Vega FM (2004), Dai MS (2004), Dai MS (2004), Groenroos E (2004), Ohkubo S (2006), Sui G (2004), Di Stefano V (2004), Brignone C (2004), Katayama H (2004), Linares LK (2003), OKeefe K (2003), Wang W (2003), Blattner C (2002), Matt T (2004), Matt T (2004), Eyckerman S (2005), Shimizu H (2002), Shimizu H (2002), Migliorini D (2002), Gu J (2001), Sengupta S (2001), Chernov MV (2001), Cross B (2011), Cross B (2011), Cross B (2011), Buschmann T (2001), Nakamura S (2000), Rodriguez MS (2000), Rodriguez MS (2000), Geyer RK (2000), Zaika A (1999), Maki CG (1999), Chen L (2010), Chen L (2010), Lin RK (2010), Fuchs SY (1998), Xirodimas DP (2001), Fuchs SY (1998), Inoue T (2001), Wu L (2011), Du W (2009), Li DQ (2009), Illuzzi JL (2011), Oliver TG (2011), Kim MM (2007), Marchenko ND (2007), Vaseva AV (2009), Vaseva AV (2009), Lai KP (2010), Naderi EH (2011), Zdzalik M (2010), Singh RK (2007), Meng L (2011), Moore L (2007), Kim S (2010), Inoue Y (2011), Fraser JA (2010), Worrall EG (2009), Wu H (2011), Wang KS (2011), Wang KS (2011), Wang KS (2011), Izumi T (2010), Huang YF (2009), Tang J (2006), Tang J (2006), Fu X (2010), Fu X (2010), Shloush J (2011), Yadavilli S (2009), Stevenson LF (2007), Suzuki T (2010), Cheng Q (2009), Kulikov R (2010), Kulikov R (2010), Li L (2010), Li L (2010), Cheng Q (2011), Li D (2011), Nie J (2010), Demma M (2010), Sun XX (2011), Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010), Nishida T (2011), Li M (2011), Li M (2011), Amson R (2011), Amson R (2011), Bhatt P (2011), David Y (2011), Zhang Y (2010), Liu J (2010), Liu J (2010), Song MS (2008), Cummins JM (2004), Kim CK (2010), Kim CK (2010), Yan C (2010), Wang X (2011), Phillips A (2010), Phillips A (2010), Kang HN (2011), Kang HN (2011), Wang X (2004), Sionov RV (2001), Wei S (2012), Camus S (2012), Ding B (2012), Yang Z (2012), Yang Z (2012), Tripathi V (2007), Tripathi V (2007), Dai C (2011), Chen S (2012), Honda R (1997), Kinyamu HK (2003), Zhan C (2012), Zhan C (2012), Lee CW (2010), Zhou X (2012), Bouska A (2008), Wade M (2012), Ferreon JC (2009), Domenici F (2011), Uldrijan S (2007), Uldrijan S (2007), Stad R (2000), Stad R (2000), Banks D (2006), Banks D (2006), Bernal F (2010), Bernal F (2010), Jain AK (2012), Kane SA (2000), Tan Z (2000), Yang Z (2012), Wawrzynow B (2007), Wawrzynow B (2007), Wawrzynow B (2007), Hiramatsu K (2006), Bao-Lei T (2006), Kulikov R (2005), Yang Y (2005), Lindstroem MS (2007), Bech-Otschir D (2001), Li Y (2012), Gillotin S (2010), Burch L (2004), Liu WL (2001), OHagan HM (2004), OHagan HM (2004), Funari G (2009), Candeias MM (2008), Brew CT (2006), Wang J (2011), Calabro V (2002), Burch L (2004), Iyappan S (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Kurki S (2004), Tian LF (2006), Wang J (2006), Bae S (2012), Bae S (2012), Frazier DP (2012), Frazier DP (2012), Lew QJ (2012), Lew QJ (2012), Huart AS (2012), Li Z (2004), Balint E (1999), Balint E (1999), Funston G (2012), Dou X (2012), Sadagopan S (2012), Sadagopan S (2012), Dixit D (2012), Roxburgh P (2012), Xu L (2012), Drago-Ferrante R (2008), Li H (2009), Negorev D (2001), Wang X (2012), Wang X (2012), Wang X (2012), Boettger A (1997), Jung H (2008), Oliner JD (1992), Seemann S (2005), Kawai H (2007), Schuster K (2007), Dawson R (2003), DArcy P (2009), Schon O (2004), Schon O (2004), Hogan C (2008), Lottin-Divoux S (2005), Latini P (2011), Latini P (2011), Latini P (2011), McCoy MA (2003), Kussie PH (1996), Shieh SY (1997), Shieh SY (1997), Naski N (2009), Naski N (2009), Schon O (2002), Tamborini E (2001), Wade M (2006), Wade M (2006), Lohrum MA (2003), Garcia JF (2002), Garcia JF (2002), Kallen J (2009), Kulikov R (2006), Kulikov R (2006), Czarna A (2009), Czarna A (2009), Hu B (2007), Chi SW (2005), Yu GW (2006), Yu GW (2006), Saji S (2001), Chen L (1997), Zhang H (1998), Issaeva N (2004), Wade M (2008), Wade M (2008), Chen HF (2007), Chen HF (2007), Li HH (2004), Wang J (2011), Gu L (2009), Gu L (2009), Meng L (2008), Meng L (2008), Okamoto K (2006), Malaguarnera R (2008), Zhou M (2003), Zhou M (2003), Di Conza G (2012), Xirodimas DP (2004), Auger KR (2005), Li J (2011), Li J (2011), Li J (2011), Lee SJ (2007), Chau JF (2012), Lu X (2005), Mazars A (2010), Mazars A (2010), Mazars A (2010), Olson DC (1993), Picksley SM (1994), Issaeva N (2004), Issaeva N (2004), Zhang J (2012), Wen W (2013), Wen W (2013), Bursac S (2012), Yang Y (2013), Yang Y (2013), Landre V (2013), Pettersson S (2012), Thin TH (2007), Thin TH (2007), Piccinin S (2012), Shan B (2012), Caratozzolo MF (2012), Lui K (2013), Kobet E (2000), Lim KH (2010), Ranaweera RS (2013), Cui D (2013), Ebina M (2013), He Y (2013), He Y (2013), Siepe D (2009), Suh HW (2013), Zhan YA (2013), Wang J (2011), Hjerpe R (2010), Murray MF (2007), Jin L (2013), Jin L (2013), Zhang R (2013), Yan S (2013), Sun XX (2011), Heyne K (2014), Heyne K (2014), Bista M (2013), Jin J (2014), Mikawa T (2014), Qi M (2014), Cheng Q (2014), Zhang HH (2014), Perry ME (2000), Nishizaki M (2004), Sanchez-Aguilera A (2006), Chen YC (2013), Bertamino A (2013), Ding G (2013), Kubo N (2013), Kubo N (2013), Hsueh KW (2013), Kofod-Olsen E (2014), Fogeron ML (2013), Chang YS (2013), Gotoh T (2014), Gotoh T (2014), Oi N (2014), Corcoran CA (2009), Corcoran CA (2009), Ayroldi E (2014), Wu G (2014), Rajendra R (2004), Zhang J (2014), Lee MG (2014), Lee MG (2014), Freedman DA (1997), Freedman DA (1997), Saxena A (2006), Shi D (2009), Lohrum MA (2001), Lohrum MA (2001), Grossman SR (2003), Yan S (2013), Xirodimas DP (2004), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Saville MK (2004), Rodriguez MS (1999), Lui K (2013), Wu PY (2003), Pavithra L (2009), He Y (2013), Tan BX (2014), Huttlin EL (2015), Marcar L (2015), Borcherds W (2014), Borcherds W (2014), Li YC (2014), Ayroldi E (2014), Ling X (2014), Batuello CN (2015), Zhu N (2006), Mo XL (2015), Chen TC (2014), Stindt MH (2015), Caratozzolo MF (2014), Li X (2015), Saxena R (2016), Reed SM (2014), Du C (2016), Du C (2016), Du C (2016), Fraser JA (2015), Fraser JA (2015), Wu B (2015), Qin JJ (2015), Raza S (2015), Raza S (2015), Yamauchi T (2014), Yamauchi T (2014), Yamauchi T (2014), Shi Y (2010), Ahn HJ (2015), Lim KH (2015), Kang JH (2016), Chen J (2015), Liu X (2016), Yang P (2016), Yang P (2016), Liu D (2016), Liu D (2016), Liu D (2016), Datta D (2015), Reddy BA (2014), He X (2016), Shostak K (2014), Liu LJ (2016), Liu LJ (2016), Stegh AH (2010), Liu XH (2005), Medina-Medina I (2016), Medina-Medina I (2016), Kayama K (2017), Singh AK (2016), Liu WT (2016), Yue X (2016), Soares J (2015), Mukhopadhyay R (2016), Mukhopadhyay R (2016), Zhou X (2016), Zhou X (2016), Xie X (2016), Leao M (2015), Luo H (2016), Luo H (2016), Xie N (2016), Maeda R (2017), Maeda R (2017), Maeda R (2017), Sheng W (2017), Sheng W (2017), Liu M (2010), Huttlin EL (2017), Chauhan KM (2016), Goetz C (1999), Zhang J (2017), Unger T (1999), Liu Z (2004), Wu W (2015), Tan G (2017), Nomura K (2017), Lu W (2017), Lu W (2017), Hjerrild M (2001), Landre V (2017), Landre V (2017), Landre V (2017), Landre V (2017), Shangary S (2008), Shangary S (2008), Du WW (2017), Du WW (2017), Bista M (2013), Bista M (2013), Jin M (2017), LaRusch GA (2007), LaRusch GA (2007), Kurokawa M (2013), Ivanov AA (2017), Wong JH (2017), Wong JH (2017)	496
CUL7	4	NOP56	0	affinity chromatography technology	Hanson D (2014)	1
HIST1H3A	3	BAZ1B	5	imaging technique	Soldi M (2013)	1
ERCC6	6	UBC	7	pull down, pull down	Anindya R (2010), Anindya R (2010)	2
KAT2B	2	HIST1H3A	3	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, imaging technique, enzymatic study, enzymatic study	Brackertz M (2006), Seo SB (2002), Pasheva E (2004), Kouskouti A (2005), Kiernan RE (1999), Wong K (2005), Hoffmann A (2008), Shen M (2013), Yamaguchi Y (2004), Tropberger P (2013)	10
DDB1	6	PCNA	0	affinity chromatography technology	Angers S (2006)	1
TP53	0	DDB1	6	affinity chromatography technology	Fogeron ML (2013)	1
CUL4B	8	HDAC1	4	affinity chromatography technology, affinity chromatography technology, biochemical	Ji Q (2014), Ji Q (2014), Ji Q (2014)	3
HNRNPU	12	ERCC6	6	affinity chromatography technology	Hein MY (2015)	1
KAT2B	2	PARP1	3	enzymatic study	Rajamohan SB (2009)	1
RPL10	3	PARP1	3	affinity chromatography technology	Hein MY (2015)	1
BRCA1	7	VCP	6	affinity chromatography technology, pull down, affinity chromatography technology	Zhang H (2000), Zhang H (2000), Ertych N (2016)	3
ERCC6	6	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Anindya R (2010), Latini P (2011), Latini P (2011)	3
HIST1H2AB	0	ERCC6	6	affinity chromatography technology, affinity chromatography technology, far western blotting	Citterio E (2000), Citterio E (2000), Citterio E (2000)	3
BRCA1	7	DDB1	6	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
PCNA	0	POLD1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology	Ohta S (2002), Naryzhny SN (2005), Naryzhny SN (2004), Ogi T (2010), Shikata K (2001), Shikata K (2001), Xie B (2002), Li H (2006), Park JM (2014), Han J (2014), Hein MY (2015)	11
5430	0	RPA1	0	affinity chromatography technology	Fousteri M (2006)	1
VCP	6	BAX	3	affinity chromatography technology	Yu CC (2013)	1
BRCA1	7	RPA1	0	affinity chromatography technology, imaging technique, affinity chromatography technology	Suhasini AN (2011), Mok MT (2010), Tian F (2013)	3
UBC	7	NOP56	0	affinity chromatography technology	Matsumoto M (2005)	1
ERCC5	0	ERCC2	4	affinity chromatography technology, pull down	Iyer N (1996), Iyer N (1996)	2
CBX6	1	ERCC6	6	affinity chromatography technology	Vandamme J (2011)	1
TP53	0	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, pull down, x-ray crystallography, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li M (2002), Li M (2002), Li M (2002), Li M (2002), Brooks CL (2007), Brooks CL (2007), Becker K (2007), Hu M (2006), Hu M (2006), Sarkari F (2010), Marchenko ND (2007), Epping MT (2011), Qing P (2011), Tang J (2006), Ma J (2010), Dai C (2011), Holowaty MN (2003), Sheng Y (2006), Sheng Y (2006), Sheng Y (2006), Yi P (2013), Yi P (2013), Zhang J (2014), Fang Z (2013), Ye M (2015), Lim KH (2015), Lim KH (2015), Reddy BA (2014), Reddy BA (2014)	29
ERCC6	6	MDM2	2	affinity chromatography technology, affinity chromatography technology	Latini P (2011), Latini P (2011)	2
RPL10	3	HNRNPU	12	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
SPTA1	10	RPA1	0	affinity chromatography technology, affinity chromatography technology	Sridharan DM (2006), Sridharan DM (2006)	2
HDAC1	4	ERCC6	6	affinity chromatography technology	Hein MY (2015)	1
CAND1	2	HIST1H4A	0	affinity chromatography technology	Bennett EJ (2010)	1
ERCC6	6	HIST2H2AC	1	affinity chromatography technology	Anindya R (2010)	1
KAT2B	2	HIST1H2BB	3	enzymatic study	Seo SB (2002)	1
PARP1	3	PCNA	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Frouin I (2003), Cazzalini O (2010), Cazzalini O (2010), Lee CH (2010), Pozo FM (2011), Sekimoto T (2010)	6
5430	0	DDB1	6	affinity chromatography technology	Fousteri M (2006)	1
5430	0	XPA	1	affinity chromatography technology	Fousteri M (2006)	1
XPA	1	XAB2	0	two hybrid, pull down	Nakatsu Y (2000), Nakatsu Y (2000)	2
CUL4A	2	VCP	6	affinity chromatography technology	Besten Wd (2012)	1
MDM2	2	HMGN1	0	enzymatic study	Guo Z (2013)	1
ERCC3	3	ERCC2	4	biochemical, affinity chromatography technology, pull down, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down	Giglia-Mari G (2004), Marinoni JC (1997), Drapkin R (1994), Iyer N (1996), Iyer N (1996), Havugimana PC (2012), Stehling O (2012), Luo J (2015), Luo J (2015)	9
BRCA1	7	HDAC1	4	pull down	Yarden RI (1999)	1
ERCC6	6	CAND1	2	affinity chromatography technology	Latini P (2011)	1
NOP56	0	RPL10	3	affinity chromatography technology	Hayano T (2003)	1
BAX	3	ERCC6	6	affinity chromatography technology	Hein MY (2015)	1
ERCC6	6	CUL4B	8	affinity chromatography technology	Latini P (2011)	1
CUL4A	2	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Min KW (2005), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	10
KAT2B	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study	Jin Y (2002), Wang H (2008), Zhao Y (2006), Roe JS (2006), Perez RE (2010), Tang Y (2006), Zhao LY (2003), Liu L (1999), Liu L (1999), Sakaguchi K (1998), Harrod R (2003), Harrod R (2003), MacPartlin M (2005), Chen H (1999), Kang H (2009)	15
XPA	1	ERCC4	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL7	4	BAZ1B	5	affinity chromatography technology	Hanson D (2014)	1
CUL7	4	UBC	7	affinity chromatography technology	Hanson D (2014)	1
RPA1	0	PARP1	3	affinity chromatography technology	Marechal A (2014)	1
CUL4A	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Angers S (2006), Jin J (2006), Wang H (2006), Kapetanaki MG (2006), Matsuda N (2005), Hu J (2004), Hu J (2004), Hu J (2004), Ahn J (2010), Maddika S (2009), Fischer ES (2011), Tan L (2007), He YJ (2006), He YJ (2006), He YJ (2006), McCall CM (2008), McCall CM (2008), Shiyanov P (1999), Bennett EJ (2010), Gastaldello S (2012), Kanei-Ishii C (2012), Hodgson AJ (2012), Kulaksiz G (2005), Wu Z (2012), Wu Z (2012), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Rao F (2014), Wan C (2015), Liu Y (2015), Zha Z (2015), Mouysset J (2015), Gao J (2015), Yang Y (2016), Yang Y (2016), Scherer PC (2016), Eichner R (2016), Mo Y (2017), Mo Y (2017), Peng Z (2016), Higa LA (2006), Ohtake F (2007)	46
PARP1	3	HDAC1	4	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Hassa PO (2005), Hassa PO (2005), Hang CT (2010), Rajamohan SB (2009)	4
PCNA	0	RPA1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ohta S (2002), Ogi T (2010), Takasaki Y (2001), Gong Z (2011), Miccoli L (2005), Han J (2014)	6
TP53	0	ERCC3	3	pull down, affinity chromatography technology, pull down, pull down, pull down	Wang XW (1995), Wang XW (1995), Qadri I (2002), Qadri I (2002), Leveillard T (1996)	5
ERCC5	0	BRCA1	7	affinity chromatography technology, pull down	Trego KS (2016), Trego KS (2016)	2
VCP	6	CDK2AP1	1	affinity chromatography technology	Yu CC (2013)	1
ERCC8	1	HMGN1	0	affinity chromatography technology	Fousteri M (2006)	1
CUL4A	2	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009)	7
PARP1	3	TP53	0	affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, pull down, pull down	Gueven N (2004), Malanga M (1998), Vaziri H (1997), Vaziri H (1997), Wesierska-Gadek J (2003), Simbulan-Rosenthal CM (2003)	6
POLD1	5	RPA1	0	biochemical	Havugimana PC (2012)	1
TP53	0	HECW2	13	affinity chromatography technology	Miyazaki K (2003)	1
UBC	7	HNRNPU	12	affinity chromatography technology	Matsumoto M (2005)	1
CUL4B	8	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Min KW (2003), Bennett EJ (2010), Bennett EJ (2010), Hein MY (2015)	6
ERCC6	6	CUL7	4	affinity chromatography technology	Latini P (2011)	1
ERCC6	6	25885	0	affinity chromatography technology, affinity chromatography technology	Anindya R (2010), Shen M (2013)	2
HIST1H3A	3	HIST1H4A	0	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down	Tagami H (2004), Shiio Y (2003), Zippo A (2009), Soldi M (2013), Klement K (2014), Sato K (2012)	6
ERCC8	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Olma MH (2009)	3
ERCC6	6	COPS6	0	affinity chromatography technology	Latini P (2011)	1
PARP1	3	BRCA1	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, genetic interference, genetic interference, affinity chromatography technology	Hu Y (2014), Hu Y (2014), Hu Y (2014), Shen JP (2017), Srivas R (2016), Ertych N (2016)	6
ERCC3	3	ERCC5	0	affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Huttlin EL (2017)	2
COPS6	0	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Olma MH (2009)	5
COPS6	0	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Enchev RI (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
CAND1	2	NOP56	0	affinity chromatography technology	Bennett EJ (2010)	1
USP7	14	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, unspecified method, biochemical, x-ray crystallography, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lu X (2007), Becker K (2007), Pereg Y (2006), Hu M (2006), Hu M (2006), Hu M (2006), Hu M (2006), Sarkari F (2010), Sarkari F (2010), Tang J (2006), Tang J (2006), Ma J (2010), Song MS (2008), Sheng Y (2006), Sheng Y (2006), Sheng Y (2006), Ye M (2015), Lim KH (2015), Reddy BA (2014), Rouge L (2016), Nihira NT (2017), Nihira NT (2017), Mungamuri SK (2016), Mungamuri SK (2016), Sun Y (2017)	25
DDB1	6	COPS4	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Angers S (2006), Jin J (2006), Emberley ED (2012), Olma MH (2009)	4
HIST1H4A	0	HIST2H2AC	1	pull down, pull down	Shiio Y (2003), Boenisch C (2012)	2
5430	0	ERCC8	1	affinity chromatography technology	Fousteri M (2006)	1
PARP1	3	HIST1H4A	0	enzymatic study	Rajamohan SB (2009)	1
CUL4A	2	UBC	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Angers S (2006), Bennett EJ (2010), Olma MH (2009), Wu K (2016)	4
MDM2	2	HNRNPU	12	affinity chromatography technology, affinity chromatography technology	Okoro DR (2013), Jacob AG (2014)	2
NOP56	0	ERCC6	6	affinity chromatography technology	Hein MY (2015)	1
CUL4B	8	PCNA	0	affinity chromatography technology	Banks D (2006)	1
ERCC6	6	COPS4	0	affinity chromatography technology	Latini P (2011)	1
RPA1	0	HNRNPU	12	affinity chromatography technology	Marechal A (2014)	1
CUL4B	8	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Hein MY (2015), Yang Y (2015)	4
PARP1	3	HMGN1	0	enzymatic study	Bonfiglio JJ (2017)	1
CUL4B	8	UBC	7	affinity chromatography technology, pull down	Bennett EJ (2010), Nathan JA (2013)	2
TP53	0	CUL7	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Andrews P (2006), Andrews P (2006), Andrews P (2006), Dowell JD (2007), Dowell JD (2007), Dowell JD (2007), Skaar JR (2007), Skaar JR (2007), Kim SS (2007), Kim SS (2007), Kim SS (2007), Kaustov L (2007), Kasper JS (2006), Kasper JS (2006), Kasper JS (2006), Fogeron ML (2013), Hanson D (2014), Hanson D (2014), Huttlin EL (2015), Li X (2015), Huttlin EL (2017), Guo H (2014)	22
CUL7	4	RPA1	0	affinity chromatography technology	Hanson D (2014)	1
HDAC1	4	MDM2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Ito A (2002), Ito A (2002), Ito A (2002), Gaughan L (2005), Gaughan L (2005)	5
TP53	0	HNRNPU	12	affinity chromatography technology	Fogeron ML (2013)	1
CUL7	4	PCNA	0	affinity chromatography technology	Hanson D (2014)	1
MPHOSPH8	1	HIST1H3A	3	unspecified method	Sun L (2015)	1
ERCC8	1	PCNA	0	affinity chromatography technology	Fei J (2012)	1
CBX6	1	RPL10	3	affinity chromatography technology	Hauri S (2016)	1
XPA	1	DDB1	6	pull down	Wakasugi M (2009)	1
KAT2B	2	5430	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Cho H (1998), Cho H (1998), Obrdlik A (2008), Obrdlik A (2008)	4
5430	0	ERCC3	3	affinity chromatography technology	Fousteri M (2006)	1
TP53	0	PCNA	0	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Banks D (2006), Banks D (2006), Hampp S (2016), Hampp S (2016)	4
RPA1	0	UBC	7	affinity chromatography technology	Marechal A (2014)	1
DDB1	6	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Jin J (2006), Groisman R (2003), Groisman R (2003), Meulenbroek EM (2012), Fei J (2012), Jin J (2006), He J (2016), Groisman R (2006), Chitale S (2017), Ohtake F (2007)	10
ERCC6	6	HMGN1	0	affinity chromatography technology	Anindya R (2010)	1
BRCA1	7	USP7	14	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
ERCC6	6	5430	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Anindya R (2010), Fousteri M (2006), Fousteri M (2006)	3
COPS6	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	12
CUL4B	8	HIST1H2AB	0	affinity chromatography technology	Bennett EJ (2010)	1
ERCC6	6	XPA	1	pull down, affinity chromatography technology	Selby CP (1997), Anindya R (2010)	2
CUL7	4	5430	0	affinity chromatography technology	Hanson D (2014)	1
COPS4	0	POLD1	5	genetic interference	Horlbeck MA (2018)	1
COPS6	0	UBC	7	affinity chromatography technology	Bennett EJ (2010)	1
RNF11	0	ERCC6	6	two hybrid	Colland F (2004)	1
HIST1H2AB	0	UBC	7	affinity chromatography technology	Sharma N (2013)	1
ERCC6	6	COPS3	1	affinity chromatography technology	Latini P (2011)	1
TP53	0	ERCC2	4	pull down, far western blotting, pull down	Wang XW (1995), Leveillard T (1996), Leveillard T (1996)	3
CUL7	4	RPL10	3	affinity chromatography technology	Hanson D (2014)	1
CUL4B	8	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Fei J (2012), Hein MY (2015)	3
BRCA1	7	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, biochemical, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2004), Ouchi T (1998), Dong Y (2003), Dong Y (2003), Chai YL (1999), Chai YL (1999), Zhang H (1998), Dong Y (2003), Chen Y (2006), Quaresima B (2006), Zhang H (1998), Zhang H (1998), Mark WY (2005), Jin S (2009), Jiang J (2011), Rasti M (2015), Rasti M (2015)	17
CAND1	2	SSBP1	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL7	4	PARP1	3	affinity chromatography technology	Hanson D (2014)	1
UBC	7	BRCA1	7	pull down, enzymatic study	Sobhian B (2007), Zhao GY (2007)	2
CUL4A	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guerrero-Santoro J (2008), Angers S (2006), Bennett EJ (2010), Bennett EJ (2010), Sertic S (2013)	5
XAB2	0	ERCC6	6	affinity chromatography technology	Nakatsu Y (2000)	1
ERCC6	6	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study	Anindya R (2010), Fousteri M (2006), Henning KA (1995), Latini P (2011), Latini P (2011), Fei J (2012), He J (2016), Groisman R (2006), Groisman R (2006), Groisman R (2006)	10
VCP	6	COPS3	1	affinity chromatography technology	Yu CC (2013)	1
ERCC5	0	PCNA	0	pull down	Gary R (1997)	1
SPTA1	10	ERCC2	4	affinity chromatography technology, affinity chromatography technology	Sridharan DM (2006), Sridharan DM (2006)	2
TP53	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique	Ito A (2002), Wang C (2005), Dohi Y (2008), Jin W (2008), Lei Q (2006), Wu Y (2001), Wu Y (2001), Luo J (2000), Juan LJ (2000), Juan LJ (2000), Juan LJ (2000), Murphy M (1999), Insinga A (2004), Sun JM (2007), Yu XY (2010), Sinha S (2010), Sinha S (2010), Li Y (2012), Di Agostino S (2006), Pavithra L (2009), Pavithra L (2009), Luo J (2000), Chen TC (2014), Park EK (2015), Park EK (2015), Park EK (2015)	26
HNRNPU	12	5430	0	affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Kim MK (1999), Vizlin-Hodzic D (2011), Kukalev A (2005), Obrdlik A (2008), Obrdlik A (2008), Obrdlik A (2008)	6
SPTA1	10	ERCC6	6	affinity chromatography technology, affinity chromatography technology	Sridharan DM (2006), Sridharan DM (2006)	2
CUL4A	2	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Lo YH (2012), Banks D (2006)	3
ERCC8	1	OGG1	0	affinity chromatography technology	Kamenisch Y (2010)	1
PCNA	0	HDAC1	4	affinity chromatography technology, pull down, affinity chromatography technology	Milutinovic S (2002), Milutinovic S (2002), Naryzhny SN (2004)	3
5430	0	ERCC5	0	affinity chromatography technology, affinity chromatography technology, pull down	Fousteri M (2006), Sarker AH (2005), Sarker AH (2005)	3
ERCC8	1	SSBP1	0	affinity chromatography technology	Kamenisch Y (2010)	1
KAT2B	2	25885	0	affinity chromatography technology, imaging technique	Shen M (2013), Shen M (2013)	2
VCP	6	ERCC6	6	affinity chromatography technology	He J (2016)	1
CDK2AP1	1	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Spruijt CG (2010), Bantscheff M (2011), Joshi P (2013), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	6
BRCA1	7	NOP56	0	affinity chromatography technology	Ertych N (2016)	1
5430	0	PCNA	0	affinity chromatography technology	Kang H (2011)	1
RPA1	0	DDB1	6	affinity chromatography technology	Marechal A (2014)	1
CUL4B	8	TP53	0	affinity chromatography technology	Thirunavukarasou A (2014)	1
HIST1H2AB	0	HIST1H2BB	3	pull down	Sato K (2012)	1
5430	0	HMGN1	0	affinity chromatography technology	Fousteri M (2006)	1
CBX6	1	HIST1H2AB	0	affinity chromatography technology	Vandamme J (2011)	1
CAND1	2	HIST1H2AB	0	affinity chromatography technology	Bennett EJ (2010)	1
CAND1	2	PARP1	3	affinity chromatography technology	Bennett EJ (2010)	1
HECW2	13	ERCC6	6	affinity chromatography technology	Lu L (2013)	1
ERCC6	6	BRCA1	7	affinity chromatography technology, enzymatic study	Wei L (2011), Wei L (2011)	2
CUL4A	2	HIST1H2AB	0	affinity chromatography technology	Bennett EJ (2010)	1
ERCC6	6	POLD1	5	affinity chromatography technology	Anindya R (2010)	1
CUL4B	8	USP7	14	affinity chromatography technology	Bennett EJ (2010)	1
HNRNPU	12	BAZ1B	5	affinity chromatography technology	Hein MY (2015)	1
BRCA1	7	HIST2H2AC	1	enzymatic study, enzymatic study	Chen A (2002), Thakar A (2010)	2
VCP	6	5430	0	affinity chromatography technology, affinity chromatography technology	He J (2017), He J (2017)	2
ERCC3	3	USP7	14	affinity chromatography technology	Huttlin EL (2017)	1
ERCC6	6	ERCC2	4	affinity chromatography technology	Anindya R (2010)	1
USP7	14	UBC	7	enzymatic study, enzymatic study, unspecified method, enzymatic study, pull down	Bremm A (2010), Faesen AC (2011), Ernst A (2013), Holowaty MN (2003), Kwasna D (2018)	5
ERCC6	6	ERCC5	0	affinity chromatography technology, far western blotting	Fousteri M (2006), Sarker AH (2005)	2
ERCC6	6	PCNA	0	affinity chromatography technology	Anindya R (2010)	1
VCP	6	MDM2	2	affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Okoro DR (2013)	2
CUL7	4	HIST1H4A	0	affinity chromatography technology	Hanson D (2014)	1
RNF11	0	UBC	7	two hybrid, two hybrid	Li H (2004), Colland F (2004)	2
PCNA	0	MDM2	2	affinity chromatography technology, affinity chromatography technology	Groehler AL (2010), Banks D (2006)	2
ERCC6	6	ERCC3	3	affinity chromatography technology	Fousteri M (2006)	1
KAT2B	2	HIST2H2AC	1	enzymatic study	Yang XJ (1996)	1
HIST1H3A	3	HDAC1	4	affinity chromatography technology, pull down, affinity chromatography technology	Nishioka K (2002), Li X (2014), Hein MY (2015)	3
DDB1	6	CAND1	2	affinity chromatography technology	Hu J (2004)	1
KAT2B	2	ERCC6	6	affinity chromatography technology, affinity chromatography technology, imaging technique	Shen M (2013), Shen M (2013), Shen M (2013)	3
RPL10	3	ERCC6	6	affinity chromatography technology	Hein MY (2015)	1
RPA1	0	USP7	14	affinity chromatography technology	Marechal A (2014)	1
SPTA1	10	XPA	1	affinity chromatography technology, affinity chromatography technology	Sridharan DM (2006), Sridharan DM (2006)	2
CUL4A	2	SSBP1	0	affinity chromatography technology	Bennett EJ (2010)	1
CDK2AP1	1	ERCC6	6	affinity chromatography technology	Hein MY (2015)	1