Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
ABCA3 rs150929 GG + GT imatinib efficacy yes Within patients who were responders to imatinib treatment (those with complete cytogenetic response (CCyR)), those with the GG or GT genotype had six times more probability of not achieving complete molecular response (CMR) as compared to those with the TT genotype. Please note that alleles have been complemented to the plus chromosomal strand. Genotypes GG + GT is associated with decreased response to imatinib in people with Leukemia, Myelogenous, Chronic, BCR-ABL Positive as compared to genotype TT. 25056761 1447959896