Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
F11 2160 CHEMBL273653 CHEMBL273653 inhibitor GuideToPharmacologyInteractions
F11 2160 NONACOG ALFA CHEMBL2109205 ligand DrugBank 10593931, 659613, 11342438
F11 2160 DEXTRAN SULFATE SODIUM CHEMBL2108952 NCI 12968031
F11 2160 CONESTAT ALFA CHEMBL2108350 inhibitor DrugBank 16267649
F11 2160 THROMBIN CHEMBL2108110 NCI 9787166

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
F11 rs3756009 G warfarin dosage no Samples, genotypes and INRs from a cohort of 551 patients were used to derive an algorithm which was used to predict daily warfarin maintenance dose in a second cohort of 236 patients. Note: the authors state that "SNPs were tested for deviations from HWE using the chi-squared test, and for their association with the warfarin dose by Spearman correlation analysis using a *co-dominant* model." Allele G is not associated with dose of warfarin in people with heart valve replacement as compared to allele A. 25126975 1184757050