Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
FCER1A 2205 OMALIZUMAB CHEMBL1201589 TdgClinicalTrial, DrugBank 15356552, 17368811
FCER1A 2205 TALIZUMAB CHEMBL2107888 DrugBank
FCER1A 2205 R-112 CHEMBL3545399 TdgClinicalTrial
FCER1A 2205 BENZYLPENICILLOYL POLYLYSINE CHEMBL1201779 agonist TdgClinicalTrial, TEND, DrugBank 11752352, 17139284, 17016423, 7436456

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
FCER1A rs2494262 A desloratadine efficacy no No difference found in efficacy of non sedating H1-antihistimines in patients by the genotype at rs2494262. Allele A is not associated with response to desloratadine and mizolastine in people with Urticaria as compared to allele C. 25412950 1447520990
FCER1A rs2298805 AA desloratadine efficacy yes Genotype AA is associated with increased response to desloratadine and mizolastine in people with Urticaria as compared to genotypes AG + GG. 25412950 1447520868
FCER1A rs10908703 A desloratadine efficacy no No difference was found in risk of spontaneous chronic urticaria or in efficacy of desloratadine or mizolastine treatment. Allele A is not associated with response to desloratadine and mizolastine in people with Urticaria as compared to allele G. 25412950 1447520961