Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
AKR7A3	rs2231198	CC	bupropion	metabolism/PK	no	Volunteers were given six different formulations of bupropion and PK parameters were assessed. NMo differences in the ratio of the AUC of metabolite: AUC of bupropion between genotypes. Please note: alleles have been complemented to the + chromosomal strand.	Genotype CC is not associated with metabolism of bupropion in healthy individuals as compared to genotypes CT + TT.	28685396	1448639061
AKR7A3	rs2013249	CC	bupropion	metabolism/PK	no	Volunteers were given six different formulations of bupropion and PK parameters were assessed. NMo differences in the ratio of the AUC of metabolite: AUC of bupropion between genotypes. Please note: alleles have been complemented to the + chromosomal strand.	Genotype CC is not associated with metabolism of bupropion in healthy individuals as compared to genotypes CG + GG.	28685396	1448639083