PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
YWHAQ	0	TSC2	17	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical	Ewing RM (2007), Pozuelo-Rubio M (2010), Meek SE (2004), Pozuelo-Rubio M (2010), Pozuelo-Rubio M (2010)	5
FOXO1	2	PML	7	affinity chromatography technology, affinity chromatography technology	Kitamura YI (2005), Kitamura YI (2005)	2
SMAD3	1	NCOA1	6	affinity chromatography technology	Li G (2006)	1
NLK	1	MDM2	2	affinity chromatography technology	Zhang HH (2014)	1
YWHAQ	0	YWHAG	5	affinity chromatography technology, biochemical	Pozuelo-Rubio M (2010), Kristensen AR (2012)	2
EP300	36	SMAD3	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Qiu P (2006), Furumatsu T (2005), Itoh S (2000), Akiyoshi S (1999), Abecassis L (2004), Kaimori A (2010), Janknecht R (1998), Janknecht R (1998), Nishihara A (1999), Nishihara A (1999), Furumatsu T (2005), Ghosh AK (2004), Shen X (1998), Shen X (1998), Ghosh AK (2001), Postigo AA (2003), Postigo AA (2003), Yang WS (2005), Lim JY (2012), Lim JY (2012), Jinnin M (2007), Wang G (2005)	22
FOXO1	2	FOXO4	0	affinity chromatography technology	Li X (2015)	1
XPO1	8	YWHAG	5	affinity chromatography technology	Kirli K (2015)	1
SMAD4	9	HNF4A	2	pull down	Kardassis D (2000)	1
IRF3	4	AKT1	1	affinity chromatography technology	Joung SM (2011)	1
AKT1	1	FOXO1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, imaging technique	Matsuzaki H (2005), Brent MM (2008), Rena G (1999), Tang ED (1999), Chen TC (2014)	5
ESR1	0	FOXO1	2	two hybrid, pull down, two hybrid, pull down, affinity chromatography technology	Schuur ER (2001), Schuur ER (2001), Zhao HH (2001), Zhao HH (2001), Castoria G (2012)	5
100132074	0	FOXO1	2	affinity chromatography technology	Li X (2015)	1
FHL2	0	SMAD3	1	pull down, affinity chromatography technology	Ding L (2009), Ding L (2009)	2
FOXO1	2	FOXO1	2	affinity chromatography technology	Li X (2015)	1
EP300	36	SMAD4	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology	Kim RH (2000), Luciakova K (2008), Janknecht R (1998), Chung CL (2011), Shen X (1998), Dornan D (2003), Yang Y (2015)	7
SFN	1	FOXO4	0	two hybrid	Rolland T (2014)	1
PML	7	RB1	2	affinity chromatography technology, affinity chromatography technology, pull down	Alcalay M (1998), Alcalay M (1998), Alcalay M (1998)	3
AKT1	1	AR	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin HK (2001), Lin HK (2001), Deep G (2008), Deep G (2008), Steely AM (2017)	5
CCNB1	3	EP300	36	pull down, affinity chromatography technology	Felzien LK (1998), Felzien LK (1998)	2
MDM2	2	SIRT1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology	Nihira NT (2017), Nihira NT (2017), Nihira NT (2017)	3
EP300	36	PARP1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Messner S (2009), Hassa PO (2005), Hassa PO (2005), Hassa PO (2005), Hassa PO (2008), Hassa PO (2008), Hassa PO (2003), Hassa PO (2003), Hassa PO (2003), Kim BK (2014), Kim BK (2014)	11
FHL2	0	SMAD4	9	pull down, affinity chromatography technology	Ding L (2009), Ding L (2009)	2
SATB1	1	EP300	36	pull down, affinity chromatography technology, affinity chromatography technology	Fujii Y (2003), Fujii Y (2003), Fujii Y (2003)	3
ESR1	0	SFN	1	affinity chromatography technology	Tarallo R (2011)	1
SETD7	2	ESR1	0	unspecified method, enzymatic study, enzymatic study	Subramanian K (2008), Subramanian K (2008), Zhang X (2013)	3
SFN	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Yang HY (2007), Yang HY (2007), Yang HY (2007), Wood NT (2009)	4
NLK	1	SKP2	2	affinity chromatography technology	Kanei-Ishii C (2008)	1
AR	3	SMAD3	1	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down	Chipuk JE (2002), Hayes SA (2001), Hayes SA (2001), Hayes SA (2001), Chipuk JE (2002), Hayes SA (2001), Hayes SA (2001), Kang HY (2002), Kang HY (2002), Kang HY (2002), Kang HY (2002), Chipuk JE (2002)	12
AKT1	1	CREBBP	29	pull down, enzymatic study	Drendall CI (2010), Drendall CI (2010)	2
FOXO1	2	CRY1	0	affinity chromatography technology	Jang H (2016)	1
CDKN1A	1	YWHAQ	0	affinity chromatography technology, affinity chromatography technology, pull down	Wang B (2010), Wang B (2010), Wang B (2010)	3
AKT1	1	SFN	1	affinity chromatography technology, affinity chromatography technology	Calvo N (2010), Calvo N (2010)	2
FOXO1	2	HOXA11	0	affinity chromatography technology	Lynch VJ (2009)	1
PML	7	CREBBP	29	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Matsuzaki K (2003), Matsuzaki K (2003), Matsuzaki K (2003), Doucas V (1999), Doucas V (1999), Zhong S (1999), Chen Y (2015)	7
SKP2	2	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, imaging technique	Amador V (2007), Hwang CY (2007), Calvisi DF (2009), Bendjennat M (2003), Wu L (2012), Wu L (2012), Abbas T (2008), Ungermannova D (2005), Chen TC (2014)	9
SIRT7	1	ATM	9	affinity chromatography technology	Tsai YC (2012)	1
XPO1	8	FOXO1	2	affinity chromatography technology	Kirli K (2015)	1
EP300	36	ESR1	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, enzymatic study, affinity chromatography technology, enzymatic study, pull down, pull down	Fajas L (2002), Fan S (2002), Fan S (2002), Fan S (2002), Kang YK (2002), Kang YK (2002), Hao L (2010), Jin W (2008), Cui Y (2006), Dutertre M (2003), Dutertre M (2003), Shiozawa T (2003), Kim SH (2010), Ma Y (2010), Ma Y (2010), Fujita T (2003), Likhite VS (2004), Band AM (2011), Loven MA (2004), Nalvarte I (2010), Yi P (2015)	21
SKP2	2	AR	3	imaging technique, affinity chromatography technology	Li B (2014), Li B (2014)	2
IRF3	4	EP300	36	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down	Li S (2011), Weaver BK (1998), Suhara W (2002), Suhara W (2002), Suhara W (2002), Wathelet MG (1998), Lin R (2001), Takahasi K (2010), Takahasi K (2010), Yang H (2002)	10
SKP2	2	CCNB1	3	affinity chromatography technology	Bashir T (2010)	1
YWHAQ	0	AR	3	pull down	Zilliacus J (2001)	1
CREBBP	29	NLK	1	affinity chromatography technology, enzymatic study	Kurahashi T (2005), Yasuda J (2004)	2
AKT1	1	ESR1	0	enzymatic study	Campbell RA (2001)	1
DACH1	3	SMAD4	9	affinity chromatography technology, affinity chromatography technology, pull down	Wu K (2003), Wu K (2003), Wu K (2003)	3
FHL2	0	EP300	36	pull down, affinity chromatography technology	Labalette C (2004), Labalette C (2004)	2
CCNB1	3	CDKN1A	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Amador V (2007), Garcia-Wilson E (2005), Ando T (2001), Poon RY (1996), Fogeron ML (2013), Chen TC (2014)	6
100132074	0	2310	0	affinity chromatography technology	Li X (2015)	1
SMAD4	9	FOXO1	2	affinity chromatography technology, affinity chromatography technology	Seoane J (2004), Seoane J (2004)	2
RB1	2	AR	3	pull down, pull down, two hybrid, affinity chromatography technology	Lu J (1998), Yeh S (1998), Yeh S (1998), Gamble SC (2007)	4
XPO1	8	HNF4A	2	pull down	Soutoglou E (2000)	1
AR	3	NCOA1	6	two hybrid, pull down, two hybrid, affinity chromatography technology, two hybrid, two hybrid, pull down, two hybrid	Masiello D (2004), Bevan CL (1999), Bevan CL (1999), Ueda T (2002), Needham M (2000), Wolf SS (2007), Wolf SS (2007), Chan CM (2013)	8
RFWD2	0	YWHAZ	1	imaging technique, affinity chromatography technology, pull down, affinity chromatography technology	Su CH (2010), Su CH (2010), Su CH (2010), Su CH (2010)	4
CDKN1A	1	FOXO1	2	imaging technique	Chen TC (2014)	1
ESR1	0	STUB1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Fan M (2005), Tateishi Y (2004), Tateishi Y (2004), Tateishi Y (2004), Berry NB (2008), Dhamad AE (2016)	6
SETD7	2	SIRT1	3	affinity chromatography technology, affinity chromatography technology, pull down	Liu X (2011), Liu X (2011), Liu X (2011)	3
CUX1	7	SATB1	1	pull down, affinity chromatography technology	Liu J (1999), Liu J (1999)	2
AR	3	FHL2	0	two hybrid, pull down, affinity chromatography technology	Mueller JM (2000), Mueller JM (2000), Mueller JM (2000)	3
AKT1	1	GSK3B	1	pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Thimmaiah KN (2005), Drendall CI (2010), Connor MK (2005), Hunter MG (2004), Zhu QS (2011), Li L (2003), Nam SY (2010), Yang WL (2009), Zeng L (2013), Yang H (2005), Boehme KA (2008), Cross DA (1995), Hinton CV (2007), Kapoor GS (2004), Pitre A (2012), Guo J (2016)	16
FOXO1	2	DLX5	0	affinity chromatography technology	Li X (2015)	1
FOXO1	2	YWHAG	5	affinity chromatography technology, fluorescent resonance energy transfe	Rena G (2001), Ivanov AA (2017)	2
DACH1	3	FOXO1	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EP300	36	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kitagawa M (2008), Inuzuka H (2012), Inuzuka H (2012), Oh M (2016)	4
NCOA1	6	FOXO1	2	pull down	Nasrin N (2000)	1
STUB1	4	PARP1	3	affinity chromatography technology, affinity chromatography technology	Choi JR (2016), Choi JR (2016)	2
GSK3B	1	MDM2	2	enzymatic study, affinity chromatography technology	Kulikov R (2005), Kulikov R (2005)	2
SIRT1	3	RB1	2	affinity chromatography technology	Wang C (2006)	1
SMAD4	9	AKT1	1	affinity chromatography technology	Song K (2006)	1
SIRT1	3	SATB1	1	affinity chromatography technology, affinity chromatography technology, imaging technique, enzymatic study	Xue Z (2012), Xue Z (2012), Xue Z (2012), Xue Z (2012)	4
CREBBP	29	MDM2	2	affinity chromatography technology, enzymatic study, affinity chromatography technology	Inoue Y (2011), Wang X (2004), Sanchez M (2012)	3
EP300	36	YWHAZ	1	enzymatic study	Mortenson JB (2015)	1
CEBPB	2	EP300	36	genetic interference, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, imaging technique, affinity chromatography technology	Mink S (1997), Mink S (1997), Mink S (1997), Mink S (1997), Mink S (1997), Deng WG (2004), Deng WG (2004), Deng WG (2003)	8
FSHR	2	FOXO1	2	affinity chromatography technology	Nechamen CA (2007)	1
ESR1	0	NCOA1	6	pull down, pull down, pull down, pull down, two hybrid, pull down, affinity chromatography technology, pull down, fluorescent resonance energy transfe, pull down, pull down, two hybrid, pull down, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, two hybrid, fluorescent resonance energy transfe, unspecified method, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, two hybrid, pull down, pull down, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	DiRenzo J (2000), Sheppard HM (2001), Kalkhoven E (1998), Kang YK (2002), Dutertre M (2003), Dutertre M (2003), Shiozawa T (2003), Tremblay A (2001), Llopis J (2000), Chien PY (1999), Webb P (1998), Webb P (1998), Lazennec G (1997), Heery DM (1997), Heery DM (1997), Torchia J (1997), Torchia J (1997), Fleming FJ (2004), Fujita T (2003), Fujita T (2003), Monroe DG (2003), Bai Y (2003), Bramlett KS (2001), Kraichely DM (2000), Kraichely DM (2000), Gong EY (2010), Eng FC (1998), Needham M (2000), Needham M (2000), Chan CM (2013), Kim HJ (1999), Flajollet S (2007), Albers M (2005), Kurtev V (2004), DiRenzo J (1997), Han SJ (2016), Han SJ (2016)	37
SIRT1	3	TSC2	17	affinity chromatography technology, affinity chromatography technology	Ghosh HS (2010), Ghosh HS (2010)	2
ESR1	0	CREBBP	29	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Sheppard HM (2001), Fan S (2002), Fan S (2002), Fan S (2002), Jin W (2008), Jaber BM (2004), Jaber BM (2004), Heery DM (1997), Ku TK (2007), Crowe DL (2006)	10
SMAD4	9	IRF3	4	affinity chromatography technology	Qing J (2004)	1
SKP2	2	AKT1	1	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Roe JS (2011), Gao D (2009), Gao D (2009), Chan CH (2013)	9
MORF4L2	0	RB1	2	pull down	Tominaga K (2003)	1
HNF4A	2	SIRT1	3	affinity chromatography technology	Chanda D (2010)	1
CREBBP	29	NCOA1	6	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, pull down	Sheppard HM (2001), Sheppard HM (2001), Sheppard HM (2001), Wu RC (2002), Torchia J (1997), Torchia J (1997), Matsuda S (2004), DiRenzo J (2000), Nakuci E (2006), Ruas JL (2005), Huang SM (2002)	11
CDKN1A	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe, affinity chromatography technology, imaging technique	Zhang Z (2004), Zhang Z (2004), Zhang Z (2004), Jin Y (2003), Jin Y (2003), Wang B (2010), Xu H (2010), Xu H (2010), Frum R (2007), Chen TC (2014)	10
SIRT1	3	CCNB1	3	affinity chromatography technology	Sasaki T (2008)	1
FOXO1	2	MORF4L2	0	affinity chromatography technology	Li X (2015)	1
XPO1	8	SNX17	0	affinity chromatography technology	Kirli K (2015)	1
SIRT2	1	EP300	36	enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Black JC (2008), Han Y (2008), Han Y (2008), Han Y (2008), Delvecchio M (2013)	5
XPO1	8	PRKACA	2	affinity chromatography technology	Kirli K (2015)	1
PRKACA	2	HNF4A	2	enzymatic study	You M (2002)	1
FOXO1	2	ATG7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhao Y (2010), Han J (2012), Wang N (2013)	3
CREBBP	29	CDKN1A	1	affinity chromatography technology, imaging technique	Fritah A (2005), Chen TC (2014)	2
NLK	1	SMAD4	9	two hybrid, affinity chromatography technology	Wang J (2011), Varjosalo M (2013)	2
SMAD4	9	CEBPB	2	pull down	Choy L (2003)	1
YWHAZ	1	SFN	1	biochemical, affinity chromatography technology, affinity chromatography technology	Kristensen AR (2012), Huttlin EL (2015), Huttlin EL (2017)	3
ATG7	2	EP300	36	affinity chromatography technology, affinity chromatography technology	Lee IH (2009), Lee IH (2009)	2
XPO1	8	CRY1	0	affinity chromatography technology, affinity chromatography technology	Kirli K (2015), Papp SJ (2015)	2
EP300	36	FOXO1	2	enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Brent MM (2008), Perrot V (2005), Perrot V (2005), Perrot V (2005), Perrot V (2005), Pramanik KC (2014), Pramanik KC (2014), Mahmud DL (2002), Li X (2015)	9
PIK3R3	0	FOXO1	2	two hybrid	Grossmann A (2015)	1
FOXO1	2	RECQL	1	affinity chromatography technology	Li X (2015)	1
YWHAG	5	SFN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Benzinger A (2005), Benzinger A (2005), Huttlin EL (2015), Huttlin EL (2017)	4
MDM2	2	SMARCA4	19	unspecified method	Nicholson J (2014)	1
TSC2	17	AKT1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Dan HC (2002), Roux PP (2004), Dan HC (2002), Dan HC (2002)	4
TSC2	17	YWHAZ	1	two hybrid, pull down, affinity chromatography technology	Nellist M (2002), Nellist M (2002), Hernandez G (2011)	3
GSK3B	1	AR	3	pull down, affinity chromatography technology	Wang L (2004), Wang L (2004)	2
HNF4A	2	SMAD3	1	affinity chromatography technology, pull down	Kardassis D (2000), Kardassis D (2000)	2
FOXO1	2	CEBPB	2	pull down	Christian M (2002)	1
HNF4A	2	NCOA1	6	two hybrid	Wang JC (1998)	1
MST1	1	FOXO1	2	enzymatic study	Brent MM (2008)	1
SMAD4	9	STUB1	4	pull down, affinity chromatography technology	Li L (2004), Li L (2004)	2
SIRT7	1	SIRT1	3	affinity chromatography technology	Jiang L (2017)	1
AKT1	1	CDKN1A	1	pull down, enzymatic study, imaging technique, enzymatic study	Heron-Milhavet L (2006), Heron-Milhavet L (2006), Chen TC (2014), Roessig L (2001)	4
PRKACA	2	FOXO1	2	enzymatic study, pull down, affinity chromatography technology	Lee JW (2011), Lee JW (2011), Lee JW (2011)	3
FOXO1	2	RARA	5	pull down	Zhao HH (2001)	1
MDM2	2	YWHAQ	0	affinity chromatography technology, pull down, affinity chromatography technology	Pereg Y (2006), Wang B (2010), Wang B (2010)	3
YWHAZ	1	YWHAG	5	biochemical, biochemical, affinity chromatography technology, fluorescent resonance energy transfe	Kristensen AR (2012), Wan C (2015), Hein MY (2015), Ivanov AA (2017)	4
PRKACA	2	YWHAZ	1	enzymatic study, pull down	Gu YM (2006), Gu YM (2006)	2
FOXO4	0	AKT1	1	affinity chromatography technology, pull down, enzymatic study	Yang H (2005), Yang H (2005), Matsuzaki H (2005)	3
SMARCA4	19	CEBPB	2	affinity chromatography technology, affinity chromatography technology	Xu R (2007), Steinberg XP (2012)	2
AR	3	SMARCA4	19	affinity chromatography technology, two hybrid, affinity chromatography technology, bioid	Wang Q (2004), van de Wijngaart DJ (2009), Dai Y (2008), Lempiaeinen JK (2017)	4
CDKN1A	1	EP300	36	pull down, affinity chromatography technology	Cazzalini O (2008), Cazzalini O (2008)	2
SMAD3	1	CEBPB	2	pull down	Choy L (2003)	1
YWHAQ	0	SFN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pozuelo-Rubio M (2010), Huttlin EL (2015), Huttlin EL (2017)	3
MDM2	2	SIRT7	1	affinity chromatography technology	Nihira NT (2017)	1
RB1	2	CDKN1A	1	affinity chromatography technology, pull down	Nakanishi M (1999), Nakanishi M (1999)	2
SIRT1	3	PARP1	3	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Rajamohan SB (2009), Rajamohan SB (2009), Rajamohan SB (2009), Rajamohan SB (2009)	4
CDKN1A	1	PARP1	3	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Frouin I (2003), Cazzalini O (2010), Cazzalini O (2010), Lee CH (2010)	4
IRF3	4	FOXO1	2	affinity chromatography technology	Lei CQ (2013)	1
STUB1	4	FOXO1	2	affinity chromatography technology	Li F (2009)	1
CREBBP	29	HOXD13	0	pull down	Shen WF (2001)	1
IRF3	4	RB1	2	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
IRF3	4	CREBBP	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Kim T (1999), Li S (2011), Weaver BK (1998), Lin R (1998), Bibeau-Poirier A (2006), Lin R (1999), Johnson J (2007), Marson A (2004), Aksoy E (2007), Devaraj SG (2007), Devaraj SG (2007), Melroe GT (2007), Melroe GT (2007), Suhara W (2002), Wathelet MG (1998), Qin BY (2005), Qin BY (2005), Lin R (2001), Lubyova B (2004), Jennings S (2005), Sarkar SN (2004), Kim H (2010), Yang H (2002), Xing J (2013), Chen Y (2015)	25
CRY1	0	LRPPRC	7	affinity chromatography technology	Papp SJ (2015)	1
LRPPRC	7	SIRT1	3	affinity chromatography technology	Hein MY (2015)	1
CREBBP	29	RARA	5	affinity chromatography technology, affinity chromatography technology	Reineke EL (2007), Tsai LN (2008)	2
FOXO1	2	SETD7	2	affinity chromatography technology	Li X (2015)	1
TNS2	3	FOXO1	2	two hybrid	Grossmann A (2015)	1
SKP2	2	RB1	2	affinity chromatography technology, affinity chromatography technology	Ji P (2004), Ji P (2004)	2
YWHAQ	0	ESR1	0	pull down	Zilliacus J (2001)	1
ESR1	0	FOXO4	0	pull down	Schuur ER (2001)	1
FOXO1	2	FHL2	0	affinity chromatography technology, affinity chromatography technology, pull down	Yang Y (2005), Yang Y (2005), Yang Y (2005)	3
AKT1	1	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Lin WN (2008), Lee IT (2010), Sundaresan NR (2011), Howie HL (2011), Chen J (2004), Chen J (2004)	6
RARA	5	PARP1	3	affinity chromatography technology, affinity chromatography technology	Pavri R (2005), Pavri R (2005)	2
SETD7	2	AR	3	affinity chromatography technology	Ko S (2011)	1
RB1	2	PIK3R3	0	affinity chromatography technology, pull down	Xia X (2003), Xia X (2003)	2
DACH1	3	SMAD3	1	affinity chromatography technology	Wu K (2003)	1
SMAD3	1	STUB1	4	pull down	Li L (2004)	1
FOXO1	2	HOXD13	0	affinity chromatography technology	Li X (2015)	1
FOXO1	2	SIRT2	1	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Daitoku H (2004), Daitoku H (2004), Daitoku H (2004), Zhao Y (2010), Pramanik KC (2014)	5
FOXO1	2	SIRT1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kitamura YI (2005), Bastien-Dionne PO (2011), Yang Y (2005), Yang Y (2005)	4
MDM2	2	RECQL	1	affinity chromatography technology	Okoro DR (2013)	1
ATM	9	FOXO1	2	imaging technique	Ochodnicka-Mackovicova K (2016)	1
TNS2	3	YWHAG	5	affinity chromatography technology	St-Denis N (2016)	1
XPO1	8	ESR1	0	affinity chromatography technology	Castoria G (2012)	1
AKT1	1	STUB1	4	affinity chromatography technology, affinity chromatography technology	Dickey CA (2008), Su CH (2011)	2
SIRT7	1	RECQL	1	affinity chromatography technology	Tsai YC (2012)	1
HOXA5	0	FOXO1	2	pull down	Foucher I (2002)	1
FOXO1	2	2310	0	affinity chromatography technology	Li X (2015)	1
NLK	1	FOXO4	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Szypowska AA (2011), Szypowska AA (2011), Szypowska AA (2011)	3
SIRT7	1	LRPPRC	7	affinity chromatography technology	Tsai YC (2012)	1
CEBPB	2	RB1	2	pull down, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology	Charles A (2001), Wang J (2008), Chen PL (1996), Chen PL (1996), Chen PL (1996), Chen PL (1996)	6
RB1	2	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study	Iyer NG (2007), Iyer NG (2007), Chan HM (2001)	3
CEBPB	2	AR	3	pull down	Boruk M (1998)	1
SMAD3	1	FOXO1	2	affinity chromatography technology	Seoane J (2004)	1
AKT1	1	YWHAG	5	affinity chromatography technology	Klein JB (2005)	1
FOXO1	2	DNAJC9	0	affinity chromatography technology	Li X (2015)	1
SFN	1	FOXO1	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RARA	5	AKT1	1	affinity chromatography technology, enzymatic study, pull down	Srinivas H (2006), Srinivas H (2006), Srinivas H (2006)	3
PML	7	RARA	5	pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhong S (1999), Zhong S (1999), Minucci S (2000), Kraemer OH (2008), Wang K (2010), Wang K (2010), Cote S (2000), Bellodi C (2006), Villa R (2007)	9
CRY1	0	YWHAQ	0	affinity chromatography technology	Papp SJ (2015)	1
SIRT2	1	MDM2	2	enzymatic study	Nihira NT (2017)	1
SIRT7	1	XPO1	8	affinity chromatography technology	Tsai YC (2012)	1
CEBPB	2	CREBBP	29	pull down	Kovacs KA (2003)	1
AR	3	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Dai Y (2008), Minges JT (2013), Zhong J (2014), Fu M (2000), McClurg UL (2016), Tan G (2017)	6
SIRT7	1	SMARCA4	19	affinity chromatography technology	Tsai YC (2012)	1
RARA	5	NCOA1	6	pull down, pull down, fluorescent resonance energy transfe, pull down, pull down, affinity chromatography technology, two hybrid, pull down, pull down, pull down, pull down	Llopis J (2000), Llopis J (2000), Llopis J (2000), Mouchon A (1999), Torchia J (1997), Reineke EL (2007), Chan CM (2013), Kim HJ (1999), Flajollet S (2007), Cai SY (2010), DiRenzo J (1997)	11
CRY1	0	YWHAZ	1	affinity chromatography technology	Papp SJ (2015)	1
GSK3B	1	PRKACA	2	affinity chromatography technology, enzymatic study, affinity chromatography technology	Fang X (2000), Fang X (2000), Varjosalo M (2013)	3
XPO1	8	IRF3	4	affinity chromatography technology	Kirli K (2015)	1
FSHR	2	YWHAQ	0	two hybrid, affinity chromatography technology	Cohen BD (2004), Cohen BD (2004)	2
FOXO4	0	XPO1	8	pull down	Brownawell AM (2001)	1
SMAD3	1	FOXO4	0	affinity chromatography technology	Seoane J (2004)	1
CREBBP	29	SMAD3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kang JS (2005), Alliston T (2005), Xi Q (2008), Cui Q (2005), Cui Q (2005), Chen W (2007), Nishihara A (1999), Tomita M (2004), Oussaief L (2009), Oussaief L (2009), Cui Q (2005)	11
XPO1	8	CCNB1	3	affinity chromatography technology	Kirli K (2015)	1
PML	7	MDM2	2	affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bernardi R (2004), Bernardi R (2004), Zhu H (2003), Zhu H (2003), Kurki S (2003), Kurki S (2003), Wei X (2003), Wei X (2003), Wu Q (2009), Chu Y (2011), Yang Q (2013), Yang Q (2013), Bursac S (2012)	13
MDM2	2	AKT1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique	Lin HK (2002), Ogawara Y (2002), Zhou BP (2001), Zhou BP (2001), Kim CK (2011), Kim CK (2011), Zhu QS (2011), Milne D (2004), Deep G (2008), Deep G (2008), Chen TC (2014)	11
ESR1	0	PARP1	3	affinity chromatography technology, affinity chromatography technology	Ju BG (2006), Tarallo R (2011)	2
SMAD3	1	TSC2	17	affinity chromatography technology, affinity chromatography technology, pull down	Birchenall-Roberts MC (2004), Birchenall-Roberts MC (2004), Birchenall-Roberts MC (2004)	3
SIRT7	1	FOXO1	2	affinity chromatography technology	Jiang L (2017)	1
FOXO1	2	RB1	2	affinity chromatography technology	Li X (2015)	1
RB1	2	MDM2	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Hsieh JK (1999), Nguyen DX (2004), Zheng Z (2012), Sdek P (2005), Delston RB (2011), Delston RB (2011), Sdek P (2004), Sdek P (2004), Xiao ZX (1995), Xiao ZX (1995), Xiao ZX (1995), Uchida C (2006), Markham D (2006), Chan HM (2001), Chan HM (2001), Zhang H (2015), Zhang H (2015), Jaenicke RU (1996)	18
MDM2	2	FOXO4	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Brenkman AB (2008), Brenkman AB (2008), Brenkman AB (2008), Szypowska AA (2011), Szypowska AA (2011), Oteiza A (2011)	6
SMARCA4	19	CREBBP	29	genetic interference	DiRenzo J (2000)	1
RB1	2	CUX1	7	two hybrid, pull down, affinity chromatography technology	Gupta S (2003), Gupta S (2003), Gupta S (2003)	3
CREBBP	29	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Crusselle-Davis VJ (2007), Dohda T (2004), Dohda T (2004)	3
FOXO1	2	CUX1	7	affinity chromatography technology	Li X (2015)	1
YWHAQ	0	YWHAZ	1	affinity chromatography technology, biochemical, affinity chromatography technology	Pozuelo-Rubio M (2010), Kristensen AR (2012), Hein MY (2015)	3
RARA	5	SIRT1	3	affinity chromatography technology, pull down	Kang MR (2010), Kang MR (2010)	2
EP300	36	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Bouras T (2005), Bourguignon LY (2009)	2
XPO1	8	PITX1	2	affinity chromatography technology	Kirli K (2015)	1
MDM2	2	SETD7	2	pull down	Lezina L (2015)	1
LRPPRC	7	FOXO1	2	pull down	Cooper MP (2006)	1
PML	7	SATB1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Kumar PP (2007), Kumar PP (2007), Kumar PP (2007), Kumar PP (2007), Tan JA (2008)	5
GSK3B	1	FOXO1	2	imaging technique	Chen TC (2014)	1
CREBBP	29	HNF4A	2	two hybrid, affinity chromatography technology, pull down, genetic interference, pull down, pull down, enzymatic study, pull down, affinity chromatography technology	Yoshida E (1997), Yoshida E (1997), Yoshida E (1997), Yoshida E (1997), Dell H (1999), Surapureddi S (2008), Soutoglou E (2000), Soutoglou E (2000), Green VJ (1998)	9
RARA	5	EP300	36	affinity chromatography technology, affinity chromatography technology	Subbaramaiah K (2002), Reineke EL (2007)	2
CDKN1A	1	LRPPRC	7	affinity chromatography technology	Fogeron ML (2013)	1
FOXO1	2	SMARCA4	19	affinity chromatography technology	Li X (2015)	1
FOXO1	2	YWHAQ	0	affinity chromatography technology	Pramanik KC (2014)	1
RARA	5	MDM2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Ying M (2016), Ying M (2016), Ying M (2016)	3
SMAD3	1	PITX1	2	affinity chromatography technology	Lamba P (2008)	1
MDM2	2	HNF4A	2	affinity chromatography technology, affinity chromatography technology	Yang Z (2012), Yang Z (2012)	2
MORF4L2	0	SATB2	18	affinity chromatography technology	Huttlin EL (2017)	1
NLK	1	FOXO1	2	affinity chromatography technology	Szypowska AA (2011)	1
CREBBP	29	PARP1	3	enzymatic study, imaging technique	Hassa PO (2005), Chen H (2014)	2
STUB1	4	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Biswas K (2017), Biswas K (2017), Biswas K (2017)	3
TSC2	17	GSK3B	1	affinity chromatography technology, enzymatic study, affinity chromatography technology	Mak BC (2003), Inoki K (2006), Mak BC (2003)	3
XPO1	8	GSK3B	1	affinity chromatography technology	Kirli K (2015)	1
SMAD4	9	CREBBP	29	affinity chromatography technology	Yang Y (2015)	1
YWHAZ	1	XPO1	8	affinity chromatography technology	Hein MY (2015)	1
PITX1	2	FOXO1	2	pull down	Skarra DV (2013)	1
CREBBP	29	FHL2	0	affinity chromatography technology	Labalette C (2004)	1
MDM2	2	XPO1	8	affinity chromatography technology	Jacob AG (2014)	1
PML	7	SIRT1	3	affinity chromatography technology, pull down	Langley E (2002), Langley E (2002)	2
CREBBP	29	AR	3	two hybrid, pull down, pull down, genetic interference, affinity chromatography technology, pull down	Kim J (2005), Fronsdal K (1998), Ishitani K (2003), Aarnisalo P (1998), Andersen RJ (2010), Fronsdal K (1998)	6
AR	3	FOXO1	2	affinity chromatography technology, two hybrid, far western blotting	Li P (2003), Li P (2003), Li P (2003)	3
FOXO1	2	MDM2	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Fu W (2009), Fu W (2009), Fu W (2009), Fu W (2009), Jang H (2016)	5
SMAD3	1	SMAD4	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Seoane J (2004), Moren A (2003), Wu JW (2002), Nakao A (1997), Hanai J (1999), Lebrun JJ (1999), Poncelet AC (2001), Jablonska E (2010), Prunier C (2003), Kato Y (2002), Kaimori A (2010), Tang LY (2011), Tang LY (2011), Dupont S (2009), Dupont S (2009), Pardali K (2000), Kardassis D (2000), Xu L (2003), Fu G (2011), Chen W (2007), Kang JM (2012), Gao S (2009), Li H (2009), Li H (2009), Brown KA (2008), Brown KA (2008), Halder SK (2005), Barrios-Rodiles M (2005), Dai F (2007), Dai F (2007), Chacko BM (2004), Chacko BM (2004), Chacko BM (2004), Stroschein SL (1999), Stroschein SL (1999), Stroschein SL (1999), Wu RY (1997), Wu RY (1997), Wu RY (1997), Wu RY (1997), Tomita M (2004), Colland F (2004), Colland F (2004), Tang Y (2003), Ding L (2009), Fattet L (2013), Wang J (2011), Xue J (2014), Ali A (2013), Gao S (2009), Yamakawa N (2002), Yamakawa N (2002), Wang G (2005), Li X (2015), Zhou F (2014), Yang Y (2015), Yan X (2016), Yan X (2016), Wu Y (2017), Wu Y (2017)	60
CCNB1	3	RB1	2	enzymatic study, enzymatic study	Jiang W (1998), Knudsen ES (1997)	2
SMAD3	1	PML	7	affinity chromatography technology	Lin HK (2004)	1
FOXO1	2	HNF4A	2	pull down, affinity chromatography technology	Hirota K (2003), Ganjam GK (2009)	2
CREBBP	29	FOXO4	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nasrin N (2000), van der Horst A (2004), van der Horst A (2004), Szypowska AA (2011)	4
FOXO4	0	SIRT1	3	affinity chromatography technology	van der Horst A (2004)	1
TSC2	17	YWHAG	5	affinity chromatography technology	Cloutier P (2017)	1
SIRT1	3	ESR1	0	affinity chromatography technology	Elangovan S (2011)	1
ATM	9	MDM2	2	enzymatic study, enzymatic study	Wang Z (2012), Luo H (2016)	2
SMAD4	9	SKP2	2	affinity chromatography technology, affinity chromatography technology, pull down	Yang L (2006), Liang M (2004), Liang M (2004)	3
CDKN1A	1	SMAD4	9	imaging technique	Chen TC (2014)	1
MDM2	2	FHL2	0	affinity chromatography technology, pull down	Jin H (2016), Jin H (2016)	2
AR	3	STUB1	4	affinity chromatography technology, pull down, enzymatic study, unspecified method, two hybrid, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology	DaSilva J (2009), Chymkowitch P (2011), Chymkowitch P (2011), Rees I (2006), He B (2004), He B (2004), Schuelke JP (2010), McClurg UL (2016), Wang J (2016), Wang J (2016), Wang J (2016)	11
CCNB1	3	FOXO1	2	imaging technique	Chen TC (2014)	1
SKP2	2	ATM	9	affinity chromatography technology	Wu J (2012)	1
SKP2	2	STUB1	4	affinity chromatography technology	Huang Z (2004)	1
MDM2	2	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Wang L (2011), Wang L (2011)	2
CEBPB	2	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Lee SH (2010), Lee SH (2010)	2
CEBPB	2	ESR1	0	pull down, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology	Boruk M (1998), Stein B (1995), Koslowski M (2009), Dong J (2006), Dong J (2006)	5
TSC2	17	ESR1	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Finlay GA (2004), Finlay GA (2004), Finlay GA (2004), York B (2005)	4
SKP2	2	ESR1	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhou W (2014), Zhou W (2014), Zhou W (2014)	3
FOXO1	2	SATB1	1	affinity chromatography technology	Li X (2015)	1
ESR1	0	MDM2	2	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down	Liu G (2000), Kinyamu HK (2003), Duong V (2007), Duong V (2007), Duong V (2007), Duong V (2007), Saji S (2001), Saji S (2001)	8
SMAD4	9	FOXO4	0	affinity chromatography technology, affinity chromatography technology	Seoane J (2004), Seoane J (2004)	2
SMAD3	1	SMARCA4	19	affinity chromatography technology, affinity chromatography technology	Xi Q (2008), Xi Q (2008)	2
SMARCA4	19	PML	7	imaging technique	Chuang YS (2011)	1
SMARCA4	19	NCOA1	6	genetic interference	DiRenzo J (2000)	1
XPO1	8	SIRT2	1	unspecified method, affinity chromatography technology	Xu D (2012), Kirli K (2015)	2
100132074	0	FOXO4	0	affinity chromatography technology	Li X (2015)	1
SIRT1	3	AKT1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Sundaresan NR (2011), Sundaresan NR (2011), Sundaresan NR (2011)	3
SIRT1	3	AR	3	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Fu M (2006), Fu M (2006), Fu M (2006), Fu M (2006)	4
TSC2	17	FOXO1	2	affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Cao Y (2006), Cao Y (2006), Cao Y (2006), Cao Y (2006)	4
AR	3	MDM2	2	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zoubeidi A (2007), Gaughan L (2005), Gaughan L (2005), Chymkowitch P (2011), Chymkowitch P (2011), Liu T (2012), Liu T (2012), Deep G (2008), Deep G (2008), Lin HK (2002), Lin HK (2002), Zhang A (2015), Kwegyir-Afful AK (2015), McClurg UL (2016), McClurg UL (2016), Liao Y (2017), Steely AM (2017), Zhai W (2016)	18
FOXO1	2	SNX17	0	affinity chromatography technology	Li X (2015)	1
ATG7	2	SIRT1	3	affinity chromatography technology	Lee IH (2008)	1
AKT1	1	YWHAZ	1	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Powell DW (2002), Powell DW (2002), Powell DW (2002), Klein JB (2005)	4
ESR1	0	FHL2	0	two hybrid	Kobayashi S (2004)	1
RFWD2	0	FOXO1	2	affinity chromatography technology	Kato S (2008)	1
GSK3B	1	SMAD3	1	affinity chromatography technology, pull down, affinity chromatography technology	Guo X (2008), Guo X (2008), Choi SI (2011)	3
YWHAQ	0	NCOA1	6	pull down	Zilliacus J (2001)	1
FOXO1	2	YWHAZ	1	affinity chromatography technology, fluorescent resonance energy transfe	Rena G (2001), Ivanov AA (2017)	2
ATM	9	PARP1	3	pull down	Haince JF (2007)	1
ESR1	0	DNAJC9	0	affinity chromatography technology	Dhamad AE (2016)	1
FOXO1	2	SKP2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang H (2005), Huang H (2005), Huang H (2005), Calvisi DF (2009), Park J (2018), Park J (2018)	6
NCOA1	6	EP300	36	affinity chromatography technology, imaging technique, pull down, pull down	Matsuda S (2004), Wang F (2010), Kino T (2002), Nasrin N (2000)	4
RFWD2	0	SFN	1	enzymatic study	Choi HH (2011)	1
XPO1	8	SMAD4	9	affinity chromatography technology	Kirli K (2015)	1
ESR1	0	CDKN1A	1	pull down, pull down, pull down, affinity chromatography technology	Fritah A (2005), Maynadier M (2008), Maynadier M (2008), Kinyamu HK (2003)	4
SETD7	2	SMARCA4	19	affinity chromatography technology	Okabe J (2012)	1
SIRT1	3	SIRT2	1	affinity chromatography technology	Binda O (2008)	1
EP300	36	MDM2	2	pull down, affinity chromatography technology, biochemical, pull down, pull down, enzymatic study, affinity chromatography technology, biochemical, enzymatic study	Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Matt T (2004), Wang X (2004), Gillotin S (2010), Kobet E (2000), Nihira NT (2017)	9
AR	3	HNF4A	2	imaging technique	Mulholland DJ (2003)	1
SMAD3	1	AKT1	1	affinity chromatography technology, imaging technique	Song K (2006), Chen TC (2014)	2
PARP1	3	FOXO1	2	affinity chromatography technology, affinity chromatography technology, pull down	Sakamaki J (2009), Sakamaki J (2009), Sakamaki J (2009)	3
PRKACA	2	CDKN1A	1	enzymatic study	Roessig L (2001)	1
FOXO1	2	SATB2	18	affinity chromatography technology	Li X (2015)	1
SMAD3	1	ESR1	0	affinity chromatography technology	Ito I (2010)	1
CDKN1A	1	SMAD3	1	affinity chromatography technology	Dai M (2012)	1
RB1	2	SMARCA4	19	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Dunaief JL (1994), Reyes JC (1997), Qiu Z (2008), Dasgupta P (2004), Zhang HS (2000), Zhang HS (2000), Napolitano MA (2007), Dunaief JL (2002), Tu Z (2013)	9
SIRT2	1	SKP2	2	affinity chromatography technology	Li Z (2016)	1
FOXO1	2	CREBBP	29	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nasrin N (2000), Nasrin N (2000), Kitamura YI (2005), Daitoku H (2004), Daitoku H (2004), Daitoku H (2004), Daitoku H (2004), Pramanik KC (2014), Pramanik KC (2014), Li X (2015)	10
SMAD4	9	AR	3	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Kang HY (2002), Kang HY (2002), Kang HY (2002), Kang HY (2002)	4
SMARCA4	19	ESR1	0	two hybrid, pull down	Ichinose H (1997), DiRenzo J (2000)	2
CREBBP	29	CUX1	7	pull down, affinity chromatography technology	Li S (2000), Li S (2000)	2
YWHAZ	1	MDM2	2	affinity chromatography technology	Zhang B (2017)	1