PPI network (data source: BioGrid)

Symbol A GeneA coding DNM count Symbol B GeneB coding DNM count Interaction detection method Publication Evidence
PHLPP1 4 MCMBP 3 affinity chromatography technology St-Denis N (2016) 1
PHLPP1 4 WDR20 6 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid Sowa ME (2009), McClurg UL (2014), St-Denis N (2016), St-Denis N (2016) 4
PPP2R1A 8 STUB1 4 affinity chromatography technology Kong M (2009) 1
ELAVL1 0 CSNK1A1 1 affinity chromatography technology Abdelmohsen K (2009) 1
AKT1 1 MARK2 6 affinity chromatography technology, affinity chromatography technology Dickey CA (2008), Dickey CA (2008) 2
PHLPP1 4 SCRIB 8 affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Gangula NR (2013) 2
PPP2R1A 8 AKT1 1 enzymatic study Lin K (2012) 1
PHLPP2 5 USP1 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Cukras S (2016), St-Denis N (2016) 3
RFPL2 0 PHLPP1 4 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
SLC9A3R1 2 AKT1 1 affinity chromatography technology, enzymatic study Song GJ (2015), Song GJ (2015) 2
PHLPP1 4 BAG2 0 affinity chromatography technology St-Denis N (2016) 1
PHLPP1 4 PPP2R2A 0 affinity chromatography technology St-Denis N (2016) 1
TRIM25 5 ELAVL1 0 affinity chromatography technology, affinity chromatography technology Choudhury NR (2017), Choudhury NR (2017) 2
HDAC1 4 PHLPP1 4 affinity chromatography technology Hein MY (2015) 1
WDR48 2 USP1 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, pull down, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Sowa ME (2009), Lee KY (2010), Cohn MA (2007), Cohn MA (2007), Cohn MA (2007), Cohn MA (2007), Cohn MA (2007), Villamil MA (2012), Garcia-Santisteban I (2012), Garcia-Santisteban I (2012), Cohn MA (2009), Cohn MA (2009), Cohn MA (2009), Cohn MA (2007), Lehoux M (2014), Lehoux M (2014), Olazabal-Herrero A (2015), Olazabal-Herrero A (2015), Yin J (2015), Cukras S (2016), Cukras S (2016), Cukras S (2016), Huttlin EL (2017), Liang F (2016) 25
USP46 5 PHLPP1 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Sowa ME (2009), Li X (2012), Li X (2012), Li X (2012), Huttlin EL (2015), St-Denis N (2016), St-Denis N (2016), Huttlin EL (2017), Gangula NR (2013) 10
PHLPP1 4 NUDC 1 bioid St-Denis N (2016) 1
USP12 1 WDR48 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology Sowa ME (2009), Sowa ME (2009), Joo HY (2011), Cohn MA (2009), Cohn MA (2009), Cohn MA (2009), Lehoux M (2014), Lehoux M (2014), Jahan AS (2016), McClurg UL (2015), Dharadhar S (2016), Cukras S (2016), Li H (2016), Li H (2016), Gangula NR (2013) 15
PHLPP1 4 SLC9A3R2 8 affinity chromatography technology, affinity chromatography technology Sowa ME (2009), St-Denis N (2016) 2
PHLPP1 4 PPP2R1A 8 affinity chromatography technology St-Denis N (2016) 1
TRIM25 5 FANCI 1 affinity chromatography technology Choudhury NR (2017) 1
TRIM25 5 SKP2 2 affinity chromatography technology Choudhury NR (2017) 1
PPP2R1A 8 HDAC1 4 affinity chromatography technology Sablina AA (2007) 1
AKT1 1 GSK3B 1 pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study Thimmaiah KN (2005), Drendall CI (2010), Connor MK (2005), Hunter MG (2004), Zhu QS (2011), Li L (2003), Nam SY (2010), Yang WL (2009), Zeng L (2013), Yang H (2005), Boehme KA (2008), Cross DA (1995), Hinton CV (2007), Kapoor GS (2004), Pitre A (2012), Guo J (2016) 16
TRIM25 5 DMWD 3 affinity chromatography technology Choudhury NR (2017) 1
FKBP5 0 NUDCD3 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014), Luo K (2017) 5
USP46 5 PHLPP2 5 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Sowa ME (2009), Huttlin EL (2015), St-Denis N (2016), Huttlin EL (2017) 5
TRIM25 5 CSNK1A1 1 affinity chromatography technology Choudhury NR (2017) 1
SKP2 2 AKT1 1 affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Roe JS (2011), Gao D (2009), Gao D (2009), Chan CH (2013) 9
FKBP5 0 NUDC 1 affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014) 2
USP46 5 DMWD 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Sowa ME (2009), Joo HY (2011), Huttlin EL (2015), Huttlin EL (2017) 5
PHLPP1 4 PPP5C 2 affinity chromatography technology Sowa ME (2009) 1
SUGT1 1 AIP 1 affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014) 2
HDAC1 4 MAPK8 3 affinity chromatography technology Morrison BE (2006) 1
PPP2R1A 8 IRS4 2 affinity chromatography technology Fogeron ML (2013) 1
RPAP3 1 SUGT1 1 affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014) 2
MAPK8 3 RBM15 7 two hybrid Vinayagam A (2011) 1
SLC9A3R1 2 SKP2 2 affinity chromatography technology, far western blotting, unspecified method Song GJ (2015), Song GJ (2015), Song GJ (2015) 3
TRIM25 5 SNX27 5 affinity chromatography technology Choudhury NR (2017) 1
PHLPP1 4 NUDCD3 0 affinity chromatography technology, bioid St-Denis N (2016), St-Denis N (2016) 2
SKP2 2 PHLPP1 4 affinity chromatography technology Huttlin EL (2017) 1
TRIM25 5 STUB1 4 affinity chromatography technology Choudhury NR (2017) 1
TRIM25 5 PHLPP1 4 affinity chromatography technology Choudhury NR (2017) 1
PHLPP1 4 SUGT1 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology Sowa ME (2009), Gao G (2013), St-Denis N (2016), St-Denis N (2016), Gangula NR (2013) 5
FKBP5 0 SUGT1 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014) 4
FKBP5 0 PHLPP2 5 affinity chromatography technology Luo K (2017) 1
PHLPP1 4 AIP 1 bioid St-Denis N (2016) 1
ELAVL1 0 SNX6 1 affinity chromatography technology Abdelmohsen K (2009) 1
PHLPP1 4 AGTPBP1 4 bioid St-Denis N (2016) 1
BTRC 1 PHLPP1 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Li X (2009), Li X (2009), Gao G (2013) 3
PHLPP1 4 RPAP3 1 affinity chromatography technology St-Denis N (2016) 1
PPP2R1A 8 PPP2R2A 0 affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, bioid Goudreault M (2009), Zhou J (2003), Zhou J (2003), Glatter T (2009), Glatter T (2009), Sablina AA (2007), Havugimana PC (2012), Junttila MR (2007), Fogeron ML (2013), Wan C (2015), Hein MY (2015), Hein MY (2015), Boldt K (2016), Yadav L (2017), Yadav L (2017), Yadav L (2017), Yadav L (2017) 17
USP46 5 USP12 1 affinity chromatography technology, bioid Sowa ME (2009), Jahan AS (2016) 2
IRS4 2 FKBP5 0 affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014) 2
FKBP5 0 GLMN 2 affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014) 2
FANCI 1 AKT1 1 affinity chromatography technology, affinity chromatography technology, pull down Zhang X (2016), Zhang X (2016), Zhang X (2016) 3
MARK2 6 PHLPP1 4 affinity chromatography technology Sowa ME (2009) 1
MAPK8 3 AKT1 1 enzymatic study Xiao L (2010) 1
ELAVL1 0 BTRC 1 affinity chromatography technology, affinity chromatography technology Chu PC (2012), Chu PC (2012) 2
MARK2 6 PPP2R1A 8 affinity chromatography technology Hein MY (2015) 1
PHLPP1 4 COA1 0 affinity chromatography technology Gangula NR (2013) 1
PPP5C 2 BAG2 0 affinity chromatography technology Yadav L (2017) 1
AKT1 1 STUB1 4 affinity chromatography technology, affinity chromatography technology Dickey CA (2008), Su CH (2011) 2
RFPL2 0 DMWD 3 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
WDR48 2 FANCI 1 pull down, affinity chromatography technology, pull down Yang K (2011), Yang K (2011), Liang F (2016) 3
FANCI 1 PHLPP2 5 affinity chromatography technology Zhang X (2016) 1
PHLPP1 4 PHLPP2 5 affinity chromatography technology, affinity chromatography technology Sowa ME (2009), St-Denis N (2016) 2
TRIM25 5 NUDC 1 affinity chromatography technology Choudhury NR (2017) 1
PHLPP2 5 WDR20 6 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), McClurg UL (2014), St-Denis N (2016) 3
PHLPP1 4 STUB1 4 affinity chromatography technology Gangula NR (2013) 1
TRIM25 5 PPP5C 2 affinity chromatography technology Choudhury NR (2017) 1
ELAVL1 0 SKP2 2 affinity chromatography technology Abdelmohsen K (2009) 1
PHLPP1 4 BUD23 0 biochemical Havugimana PC (2012) 1
ELAVL1 0 PPP2R2A 0 affinity chromatography technology Abdelmohsen K (2009) 1
GSK3B 1 PHLPP1 4 enzymatic study Li X (2009) 1
TRIM25 5 FKBP5 0 affinity chromatography technology Choudhury NR (2017) 1
BTRC 1 BAG2 0 bioid Coyaud E (2015) 1
STUB1 4 BAG2 0 pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Dai Q (2005), Dai Q (2005), Arndt V (2005), Arndt V (2005), Arndt V (2005), Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014) 9
BTRC 1 NUDC 1 affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology Sowa ME (2009), Kim TY (2014), Coyaud E (2015), Huttlin EL (2017) 4
PHLPP2 5 SLC9A3R2 8 affinity chromatography technology, affinity chromatography technology Sowa ME (2009), St-Denis N (2016) 2
USP12 1 PHLPP1 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Sowa ME (2009), McClurg UL (2014), St-Denis N (2016), St-Denis N (2016), Gangula NR (2013), Gangula NR (2013), Gangula NR (2013) 8
PHLPP2 5 SLC9A3R1 2 affinity chromatography technology, far western blotting, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Molina JR (2012), Molina JR (2012), Molina JR (2012), Molina JR (2012), St-Denis N (2016) 6
ELAVL1 0 SNX27 5 affinity chromatography technology Abdelmohsen K (2009) 1
USP46 5 SNX6 1 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
AKT1 1 USP1 4 affinity chromatography technology Zhang X (2016) 1
USP46 5 WDR48 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Sowa ME (2009), Joo HY (2011), Cohn MA (2009), Cohn MA (2009), Lehoux M (2014), Lehoux M (2014), Huttlin EL (2015), Olazabal-Herrero A (2015), Olazabal-Herrero A (2015), Yin J (2015), Yin J (2015), Cukras S (2016), Huttlin EL (2017) 14
PPP5C 2 SUGT1 1 affinity chromatography technology Yadav L (2017) 1
PHLPP1 4 RBM15 7 affinity chromatography technology, bioid Sowa ME (2009), St-Denis N (2016) 2
TRIM25 5 BTRC 1 affinity chromatography technology Choudhury NR (2017) 1
USP12 1 WDR20 6 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Sowa ME (2009), Joo HY (2011), Jahan AS (2016), McClurg UL (2015), McClurg UL (2015), Li H (2016), Li H (2016) 8
FKBP5 0 MCMBP 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014) 4
SKP2 2 BTRC 1 affinity chromatography technology, pull down, affinity chromatography technology Wei S (2012), Wei S (2012), Wei S (2012) 3
WDR20 6 WDR48 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Sowa ME (2009), Kee Y (2010), Kee Y (2010), Kee Y (2010), McClurg UL (2015), Cukras S (2016), Huttlin EL (2017) 8
PHLPP2 5 SUGT1 1 affinity chromatography technology St-Denis N (2016) 1
PHLPP1 4 AKT1 1 affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology Mistafa O (2010), Gao T (2005), Gao T (2005), Zhang X (2016) 4
MAPK8 3 PHLPP1 4 affinity chromatography technology Hein MY (2015) 1
FKBP5 0 AKT1 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Mistafa O (2010), Luo K (2017), Luo K (2017) 3
PHLPP1 4 SNX27 5 affinity chromatography technology Sowa ME (2009) 1
TRIM25 5 NUDCD3 0 affinity chromatography technology Choudhury NR (2017) 1
SKP2 2 STUB1 4 affinity chromatography technology Huang Z (2004) 1
TRIM25 5 PPP2R1A 8 affinity chromatography technology Choudhury NR (2017) 1
ELAVL1 0 GSK3B 1 affinity chromatography technology Abdelmohsen K (2009) 1
ELAVL1 0 RBM15 7 affinity chromatography technology Abdelmohsen K (2009) 1
TRIM25 5 BUD23 0 affinity chromatography technology Choudhury NR (2017) 1
WDR48 2 PHLPP1 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down Sowa ME (2009), Sowa ME (2009), McClurg UL (2014), Cukras S (2016), St-Denis N (2016), St-Denis N (2016), Gangula NR (2013), Gangula NR (2013), Gangula NR (2013), Gangula NR (2013) 10
DMWD 3 PHLPP1 4 affinity chromatography technology Sowa ME (2009) 1
GSK3B 1 BTRC 1 affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down Kitagawa M (1999), Gao C (2014), Gao C (2014), Gao C (2014) 4
WDR48 2 DMWD 3 affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Sowa ME (2009) 2
DMWD 3 SCRIB 8 affinity chromatography technology Sowa ME (2009) 1
IRS4 2 PPP5C 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid Taipale M (2014), Taipale M (2014), Yadav L (2017), Yadav L (2017) 4
PHLPP1 4 FANCI 1 affinity chromatography technology, affinity chromatography technology Zhang X (2016), Zhang X (2016) 2
PHLPP1 4 USP1 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Sowa ME (2009), Zhiqiang Z (2012), Zhiqiang Z (2012), Zhiqiang Z (2012), Cukras S (2016), St-Denis N (2016), St-Denis N (2016), Huttlin EL (2017), Gangula NR (2013) 10
FKBP4 0 SUGT1 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014) 4
USP12 1 PHLPP2 5 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Sowa ME (2009), McClurg UL (2014), St-Denis N (2016) 4
PHLPP1 4 IRS4 2 affinity chromatography technology Gangula NR (2013) 1
PHLPP1 4 FKBP5 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), St-Denis N (2016), Luo K (2017), Luo K (2017) 4
EFNB2 0 PHLPP1 4 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
PPP5C 2 NUDC 1 affinity chromatography technology, bioid Yadav L (2017), Yadav L (2017) 2
PHLPP2 5 DMWD 3 affinity chromatography technology St-Denis N (2016) 1
GLMN 2 FKBP4 0 pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology Chambraud B (1996), Chambraud B (1996), Neye H (2001), Krummrei U (2003), Krummrei U (2003), Chambraud B (1999), Taipale M (2014), Taipale M (2014) 8
BTRC 1 CSNK1A1 1 affinity chromatography technology, bioid Coyaud E (2015), Coyaud E (2015) 2
USP12 1 DMWD 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Sowa ME (2009), Joo HY (2011) 3
SUGT1 1 SKP2 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014), Huttlin EL (2017) 3
ELAVL1 0 PHLPP1 4 affinity chromatography technology Abdelmohsen K (2009) 1
ELAVL1 0 PPP2R1A 8 affinity chromatography technology Abdelmohsen K (2009) 1
BRAP 0 PHLPP1 4 two hybrid, pull down Fatima S (2015), Fatima S (2015) 2
CSNK1A1 1 PHLPP1 4 enzymatic study Li X (2009) 1
SLC9A3R1 2 PHLPP1 4 far western blotting, far western blotting, pull down, affinity chromatography technology Molina JR (2012), Molina JR (2012), Molina JR (2012), Molina JR (2012) 4
PHLPP1 4 GLMN 2 bioid St-Denis N (2016) 1
HAVCR2 0 PHLPP1 4 affinity chromatography technology Huttlin EL (2017) 1
USP46 5 WDR20 6 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Sowa ME (2009), Kee Y (2010), Joo HY (2011), Huttlin EL (2015), Huttlin EL (2017) 6
PHLPP2 5 SNX27 5 affinity chromatography technology, affinity chromatography technology Sowa ME (2009), St-Denis N (2016) 2
PHLPP1 4 FKBP4 0 affinity chromatography technology St-Denis N (2016) 1
PHLPP1 4 SNX6 1 biochemical Havugimana PC (2012) 1
WDR48 2 PHLPP2 5 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Sowa ME (2009), McClurg UL (2014), Cukras S (2016), St-Denis N (2016), Yadav L (2017) 6
BRAP 0 SKP2 2 pull down, affinity chromatography technology Lanctot AA (2017), Lanctot AA (2017) 2
TRIM25 5 BAG2 0 affinity chromatography technology Choudhury NR (2017) 1