PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
TP53	0	DOT1L	7	genetic interference	Xie L (2013)	1
TP53	0	TP73	2	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Stindt MH (2015), Puca R (2011), De Laurenzi V (1998), Di Como CJ (1999)	4
EP300	36	FOXO3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li XN (2009), Li XN (2009), Mahmud DL (2002), Li X (2015)	4
FOXO1	2	PML	7	affinity chromatography technology, affinity chromatography technology	Kitamura YI (2005), Kitamura YI (2005)	2
RARA	5	ARNTL	2	pull down	McNamara P (2001)	1
TP53	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Wang C (2003), Akakura S (2001), Peng Y (2001), Nagata Y (1999), Wang J (2011), Burch L (2004), Taipale M (2012), Fogeron ML (2013), Walerych D (2004)	9
IRS2	6	DVL2	5	affinity chromatography technology, affinity chromatography technology	Geng Y (2014), Geng Y (2014)	2
CSNK2A1	15	MDM2	2	enzymatic study, enzymatic study	Goetz C (1999), Hjerrild M (2001)	2
AKT1	1	FOXO1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, imaging technique	Matsuzaki H (2005), Brent MM (2008), Rena G (1999), Tang ED (1999), Chen TC (2014)	5
DNMT1	5	SETD7	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, enzymatic study	Esteve PO (2009), Esteve PO (2009), Esteve PO (2009), Esteve PO (2011), Esteve PO (2011)	5
NCOR1	9	VDR	2	pull down, two hybrid, two hybrid, pull down, two hybrid, pull down, pull down	Puccetti E (2002), Tagami T (1998), Kim JY (2009), Kim JY (2009), Polly P (2000), Herdick M (2000), Herdick M (2000)	7
SIRT1	3	WRN	6	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Law IK (2009), Law IK (2009), Li K (2008), Li K (2008), Li K (2008), Li K (2008)	6
RARA	5	SUZ12	0	affinity chromatography technology	Villa R (2007)	1
HDAC4	10	SUV39H1	0	affinity chromatography technology	Zhang CL (2002)	1
IRS1	7	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Zhang J (2007), Froejdoe S (2011)	2
WRN	6	PML	7	affinity chromatography technology	Liu J (2011)	1
MAPK8	3	SIRT1	3	affinity chromatography technology, enzymatic study	Nasrin N (2009), Nasrin N (2009)	2
EP300	36	CDK1	0	affinity chromatography technology, enzymatic study	Wang SA (2014), Wang SA (2014)	2
BCL11A	14	SIRT1	3	affinity chromatography technology, pull down	Senawong T (2005), Senawong T (2005)	2
HIC1	1	MTA1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Van Rechem C (2010), Dehennaut V (2013), Dehennaut V (2013)	3
MDM2	2	KAT2B	2	pull down, affinity chromatography technology, genetic interference, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Jin Y (2002), Jin Y (2002), Jin Y (2002), Jin Y (2004), Jin Y (2004), Jung CR (2010), Morgan JE (2017)	7
CDK1	0	HSP90AA1	7	affinity chromatography technology	Garcia-Morales P (2007)	1
SREBF1	5	KAT2A	1	affinity chromatography technology	Ebmeier CC (2010)	1
DNMT1	5	SUV39H1	0	affinity chromatography technology, affinity chromatography technology	Fuks F (2003), Esteve PO (2006)	2
PPARA	1	NCOR1	9	two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down	Dowell P (1999), Dowell P (1999), Ki SH (2005), Liu MH (2008), Pourcet B (2010), Krogsdam AM (2002)	6
CLOCK	0	CSNK2B	5	two hybrid, affinity chromatography technology	Wallach T (2013), Wallach T (2013)	2
AKT1	1	DNMT1	5	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Esteve PO (2011), Esteve PO (2011), Esteve PO (2011), Esteve PO (2011)	4
SIRT1	3	NCOR1	9	pull down, affinity chromatography technology	Hisahara S (2008), Hisahara S (2008)	2
NR1H4	0	GAPDH	0	two hybrid	Albers M (2005)	1
AKT1	1	AR	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin HK (2001), Lin HK (2001), Deep G (2008), Deep G (2008), Steely AM (2017)	5
MDM2	2	SIRT1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology	Nihira NT (2017), Nihira NT (2017), Nihira NT (2017)	3
RPL6	0	RPS2	3	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
HIC1	1	HDAC4	10	affinity chromatography technology	Stankovic-Valentin N (2007)	1
EP300	36	PARP1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Messner S (2009), Hassa PO (2005), Hassa PO (2005), Hassa PO (2005), Hassa PO (2008), Hassa PO (2008), Hassa PO (2003), Hassa PO (2003), Hassa PO (2003), Kim BK (2014), Kim BK (2014)	11
KAT5	1	AR	3	enzymatic study, two hybrid, two hybrid, pull down, two hybrid, pull down	Gaughan L (2002), Gaughan L (2002), Brady ME (1999), Brady ME (1999), Gaughan L (2001), Gaughan L (2001)	6
SATB1	1	EP300	36	pull down, affinity chromatography technology, affinity chromatography technology	Fujii Y (2003), Fujii Y (2003), Fujii Y (2003)	3
TP53	0	CSNK2B	5	protein complementation assay	Srivastav RK (2011)	1
KAT5	1	SIRT1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang J (2010), Wang J (2010), Yamagata K (2009), Yamagata K (2009), Peng L (2012)	5
RPTOR	4	IRS1	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Tzatsos A (2006), Tzatsos A (2009), Tzatsos A (2009), Tzatsos A (2009)	4
MYC	2	KAT2A	1	affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe	McMahon SB (2000), Faiola F (2005), Liu X (2008), Conacci-Sorrell M (2010), Liu X (2003), Liu X (2003), Ivanov AA (2017)	7
EP300	36	CLOCK	0	pull down	Curtis AM (2004)	1
SIRT1	3	HNF1A	0	pull down, affinity chromatography technology, affinity chromatography technology	Grimm AA (2011), Grimm AA (2011), Grimm AA (2011)	3
CHEK2	2	PML	7	enzymatic study, affinity chromatography technology, affinity chromatography technology	Yang S (2002), Yang S (2002), Yang S (2002)	3
TP53	0	RPL6	0	affinity chromatography technology	Fogeron ML (2013)	1
HIC1	1	EZH2	4	affinity chromatography technology	Boulay G (2012)	1
TP53	0	PRMT1	3	pull down	An W (2004)	1
USP22	1	KAT2A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhao Y (2008), Sowa ME (2009), Lang G (2011), Armour SM (2013), Armour SM (2013), Zhang XY (2008), Zhang XY (2008), Zhang XY (2008), Wang YL (2008)	9
TP53	0	PPARGC1A	3	affinity chromatography technology, affinity chromatography technology, pull down	Sen N (2011), Sen N (2011), Sen N (2011)	3
CHEK2	2	TP53	0	affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Louria-Hayon I (2003), Shieh SY (2000), Bjorling-Poulsen M (2005), Hirao A (2000), Adams CJ (2008)	5
GAPDH	0	EP300	36	affinity chromatography technology, affinity chromatography technology	Sen N (2008), Sen N (2008)	2
JUN	0	MYC	2	affinity chromatography technology	Levy S (2010)	1
CSNK2B	5	DNMT1	5	two hybrid	Vinayagam A (2011)	1
SIRT1	3	CLOCK	0	affinity chromatography technology, pull down	Nakahata Y (2008), Nakahata Y (2008)	2
SIRT1	3	PSME3	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Liu J (2013), Liu J (2013), Liu J (2013)	3
JUN	0	CSNK2A1	15	pull down, far western blotting, enzymatic study	Yamaguchi Y (1998), Yamaguchi Y (1998), Uhle S (2003)	3
AR	3	HDAC4	10	pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study	Franco PJ (2003), Yang Y (2011), Yang Y (2011), Yang Y (2011), Yang Y (2011), Yang Y (2011)	6
KAT2B	2	AKT1	1	enzymatic study, affinity chromatography technology	Sundaresan NR (2011), Sundaresan NR (2011)	2
SIRT1	3	ZYX	2	two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology	Fujita Y (2009), Fujita Y (2009), Fujita Y (2009), Fujita Y (2009)	4
CDKL1	1	SIRT1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
SIRT1	3	CSNK2A1	15	affinity chromatography technology, affinity chromatography technology	Holloway KR (2010), Kang H (2009)	2
NR0B2	1	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Yang Z (2012), Yang Z (2012), Yang Z (2012), Yang Z (2012), Yang Z (2012)	5
PML	7	FOS	0	pull down	Vallian S (1998)	1
MYC	2	MYCN	2	affinity chromatography technology	Li X (2015)	1
TP53	0	DNMT1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Palii SS (2008), Zhang H (2013), Zhang H (2013)	3
MYC	2	EP300	36	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, enzymatic study, affinity chromatography technology, affinity chromatography technology	Faiola F (2005), Faiola F (2005), Faiola F (2005), Faiola F (2005), Faiola F (2005), Zhang K (2005), Covic M (2005), Fujii M (2006)	8
PPARGC1A	3	SIRT1	3	imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study	Amat R (2009), Nemoto S (2005), Nemoto S (2005), Nemoto S (2005)	4
GAPDH	0	AR	3	two hybrid, pull down	Koshy B (1996), Koshy B (1996)	2
HSP90AA1	7	EPAS1	6	pull down	Katschinski DM (2004)	1
EP300	36	E2F1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ji W (2014), Ianari A (2004), Aoki I (2012)	3
HSP90AA1	7	HIF1A	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hogenesch JB (1997), Qian DZ (2006), Kong X (2006), Kubo T (2004), Zhou J (2004), Fu B (2007), Choi YK (2010), Choi YK (2010), Lee JM (2011), Liu YV (2007), Liu YV (2007), Katschinski DM (2004), Katschinski DM (2004), Katschinski DM (2004), Trisciuoglio D (2010), Trisciuoglio D (2010), Ueda K (2008), Sun H (2013), Kawanami D (2009), Prince TL (2015), Prince TL (2015), Isaacs JS (2004), Lee SH (2015)	23
HSP90AA1	7	KCNA5	2	affinity chromatography technology	Taipale M (2012)	1
CHFR	5	PML	7	fluorescent resonance energy transfe	Daniels MJ (2004)	1
KCNAB2	3	KCNA4	5	affinity chromatography technology, affinity chromatography technology	Kim SJ (2013), Kim SJ (2013)	2
MTOR	14	RPTOR	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jacinto E (2004), Jacinto E (2004), Sarbassov DD (2004), Sarbassov DD (2004), Sarbassov DD (2004), Schalm SS (2003), Hara K (2002), Ha SH (2006), Wang L (2006), Frias MA (2006), Frias MA (2006), Buerger C (2006), Jacinto E (2006), McMahon LP (2005), Oshiro N (2004), Kawai S (2003), Choi KM (2003), Hara K (2002), Hara K (2002), Kim DH (2002), Kim DH (2002), Schieke SM (2006), Ha SH (2006), Wang L (2006), Frias MA (2006), Buerger C (2006), Sarbassov DD (2006), Tzatsos A (2006), Sarbassov DD (2005), Yang Q (2006), Kaizuka T (2010), Pearce LR (2007), Oh WJ (2010), Oh WJ (2010), Agrawal P (2012), Kwak D (2012), Wu D (2012), Wu D (2012), Wu D (2012), Wu D (2012), Gwinn DM (2010), Sancak Y (2007), Sancak Y (2007), Yang Q (2006), Carriere A (2011), Jacinto E (2006), Rosner M (2010), Kim DH (2003), Kim DH (2003), Carriere A (2008), Murata H (2011), Koike-Kumagai M (2009), Koike-Kumagai M (2009), Hussain S (2013), Hussain S (2013), Peterson TR (2009), Peterson TR (2009), Su WC (2009), Hernandez-Negrete I (2007), Yan X (2012), Ramirez-Rangel I (2011), Ramirez-Rangel I (2011), Martin J (2008), Martin J (2008), Linares JF (2013), Coffman K (2014), Oshiro N (2014), Thedieck K (2007), Thedieck K (2007), Thedieck K (2007), Dan HC (2008), Dan HC (2008), Dan HC (2008), Hong F (2008), Hong F (2008), Choo AY (2008), Toschi A (2009), Loewith R (2002), Xu Y (2013), Sancak Y (2010), Sancak Y (2010), Vander Haar E (2007), Vander Haar E (2007), Kaadige MR (2015), Misra UK (2014), Misra UK (2014), Thedieck K (2007), Thomas JD (2014), Park D (2014), Alayev A (2016), Alayev A (2016)	91
SIRT1	3	HIF1A	1	affinity chromatography technology, pull down, affinity chromatography technology	Lim JH (2010), Lim JH (2010), Lim JH (2010)	3
MDM2	2	ACACA	5	affinity chromatography technology	Jacob AG (2014)	1
SETD7	2	E2F1	0	enzymatic study, enzymatic study, enzymatic study	Kontaki H (2010), Xie Q (2011), Loftus SJ (2012)	3
HSP90AA1	7	MYC	2	affinity chromatography technology	Carystinos GD (2003)	1
SIRT1	3	HERC2	9	affinity chromatography technology, affinity chromatography technology	Bai B (2016), Bai B (2016)	2
CHEK2	2	KAT2B	2	affinity chromatography technology, affinity chromatography technology	Kass EM (2009), Kass EM (2009)	2
PML	7	EZH2	4	affinity chromatography technology	Villa R (2007)	1
PRMT1	3	SIRT1	3	affinity chromatography technology, enzymatic study	Lai Y (2017), Lai Y (2017)	2
NMNAT1	0	SIRT1	3	affinity chromatography technology, affinity chromatography technology, pull down	Zhang T (2009), Zhang T (2009), Zhang T (2009)	3
SIRT1	3	DOT1L	7	affinity chromatography technology, affinity chromatography technology	Zhang D (2009), Park G (2010)	2
SETD7	2	SIRT1	3	affinity chromatography technology, affinity chromatography technology, pull down	Liu X (2011), Liu X (2011), Liu X (2011)	3
HES1	0	PARP1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kannan S (2011), Kannan S (2011), Kannan S (2011)	3
CSNK2A1	15	AKT1	1	enzymatic study	Di Maira G (2005)	1
HEY2	0	HES1	0	pull down	Iso T (2001)	1
SIRT1	3	ZEB1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Byles V (2012), Zhang P (2014), Sun L (2015)	3
STK11	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MDM2	2	SUV39H1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen L (2010), Mungamuri SK (2016), Mungamuri SK (2016)	3
SIRT1	3	MYCN	2	affinity chromatography technology, affinity chromatography technology, pull down	Marshall GM (2011), Marshall GM (2011), Marshall GM (2011)	3
CDK1	0	SIRT1	3	enzymatic study, affinity chromatography technology	Sasaki T (2008), Sasaki T (2008)	2
ARNTL	2	HIF1A	1	two hybrid, pull down, two hybrid	Hogenesch JB (1998), Hogenesch JB (1998), Rolland T (2014)	3
SIRT1	3	MTOR	14	affinity chromatography technology, affinity chromatography technology	Back JH (2011), Singh BK (2016)	2
HDAC4	10	MECOM	4	affinity chromatography technology	Chakraborty S (2001)	1
KCNAB2	3	KCNA5	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim SJ (2013), Kim SJ (2013), Huttlin EL (2017)	3
MDM2	2	EZH2	4	affinity chromatography technology, affinity chromatography technology	Wienken M (2016), Wienken M (2016)	2
PPARA	1	SIRT1	3	affinity chromatography technology, pull down, pull down	Purushotham A (2009), Purushotham A (2009), Purushotham A (2009)	3
MAPK8	3	MAPT	1	enzymatic study	Goedert M (1997)	1
FOS	0	CHEK2	2	affinity chromatography technology	Li X (2015)	1
PSME3	0	TP53	0	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology	Zhang Z (2008), Zhang Z (2008), Zhang Z (2008), Liu J (2010), Liu J (2010)	5
PARP1	3	E2F1	0	pull down, imaging technique	Simbulan-Rosenthal CM (2003), Simbulan-Rosenthal CM (2003)	2
SIRT1	3	SATB1	1	affinity chromatography technology, affinity chromatography technology, imaging technique, enzymatic study	Xue Z (2012), Xue Z (2012), Xue Z (2012), Xue Z (2012)	4
EP300	36	KAT2B	2	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Kim JH (2011), Lee M (2010), Santos-Rosa H (2003), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996), Mizuguchi Y (2012)	8
SIRT1	3	HDAC4	10	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhao X (2005), Dehennaut V (2013), Dehennaut V (2013)	3
HIF1A	1	MTA1	3	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Yoo YG (2006), Yoo YG (2006), Yoo YG (2006), Moon HE (2006), Moon HE (2006)	5
MDM2	2	TRIM28	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang C (2005), Wang C (2005), Wang C (2005), Gilmore-Hebert M (2010), Okamoto K (2006), Okamoto K (2006), Okamoto K (2006)	7
SMAD7	1	TP53	0	affinity chromatography technology	Zhang S (2006)	1
SIRT1	3	DNMT1	5	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Peng L (2011), Peng L (2011), Peng L (2011), OHagan HM (2011), OHagan HM (2011)	5
HIF1A	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
JUN	0	NCOR1	9	imaging technique	Subbaramaiah K (2007)	1
SREBF1	5	AR	3	affinity chromatography technology, pull down	Suh JH (2008), Suh JH (2008)	2
SIRT1	3	TSC2	17	affinity chromatography technology, affinity chromatography technology	Ghosh HS (2010), Ghosh HS (2010)	2
DNMT1	5	E2F1	0	biochemical	Robertson KD (2000)	1
AR	3	E2F1	0	affinity chromatography technology, affinity chromatography technology	Li Y (2012), Li Y (2012)	2
MDM2	2	APEX1	1	enzymatic study, affinity chromatography technology	Busso CS (2009), Busso CS (2009)	2
SNW1	0	CDK1	0	affinity chromatography technology	Lleres D (2010)	1
PPARA	1	EP300	36	two hybrid, two hybrid, pull down, two hybrid	Dowell P (1997), Dowell P (1999), Dowell P (1999), Mochizuki K (2008)	4
SIRT1	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Lin Z (2012), Hein MY (2015)	2
SUZ12	0	AR	3	affinity chromatography technology	Cao Q (2014)	1
RPTOR	4	EP300	36	affinity chromatography technology	Wan W (2017)	1
HSP90AA1	7	SREBF1	5	affinity chromatography technology	Taipale M (2012)	1
SIRT1	3	ACACA	5	affinity chromatography technology, affinity chromatography technology	Law IK (2009), Law IK (2009)	2
HERC2	9	STK11	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Bai B (2016), Bai B (2016), Bai B (2016)	3
MAPK8	3	EP300	36	enzymatic study	See RH (2001)	1
TP73	2	MYC	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Uramoto H (2002), Uramoto H (2002), Uramoto H (2002), Watanabe K (2002), Watanabe K (2002)	5
PSME3	0	MDM2	2	affinity chromatography technology, pull down, pull down, pull down	Zhang Z (2008), Zhang Z (2008), Zhang Z (2008), Liu J (2010)	4
MAPK8	3	JUN	0	enzymatic study, enzymatic study, enzymatic study, pull down, pull down, pull down, two hybrid, pull down, enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study	Ishitani T (2003), Nishitoh H (1998), Derijard B (1994), Derijard B (1994), Yazgan O (2002), Tada K (2001), Meyer CF (1996), Cano E (1995), Cano E (1995), Trivedi AK (2007), Zhu F (2006), Zuniga A (1999), Zuniga A (1999), Higashimoto T (2008), Garcia-Guzman M (2000), Singhirunnusorn P (2005), Hofmann TG (2005), Lewis J (2004), Jeon YJ (2009), Yamashita M (2008), Ryoo K (2004), Abell AN (2005), Burns K (1998), Hirano T (2002), Gravestein LA (1998), Dadgostar H (2003), Han YH (2006), Kolluri SK (2003), Chen LY (2003), Manna SK (2010), Gallagher ED (2002), Liu HP (2011), Xia Y (1998), Funakoshi-Tago M (2005), Ho DT (2006), Wang J (2000), Choi HK (2011), Chang TS (2003), Yao K (2009), Chang TS (2003), Dai R (2000), Gupta S (1996), Gupta S (1996), Sundarrajan M (2003), Kallunki T (1994), Kallunki T (1994), Wasserman T (2010), Blonska M (2007), Lee KH (2005), Kadoya T (2005), Katagiri C (2006), Yao K (2007), Wu X (2007), Kato T (2008), Cavigelli M (1995), Katagiri C (2006), Choi BY (2005), Choi BY (2005), Yuan ZQ (2003), Phelan DR (2001), Eliopoulos AG (2006), Hayashi T (2007), Zhang J (2013), Li X (2002), Kendrick TS (2004), Holzberg D (2003), Grau R (2004), Hernandez M (2000), Hwang SG (2014), Larsson H (1999), Rausch O (1997), Morley SJ (2000), Ho JM (2002), Shkoda A (2012), Pop M (2004), Chang HY (1999)	76
AKR1D1	2	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CSNK2A1	15	NCOR1	9	affinity chromatography technology, affinity chromatography technology, enzymatic study	Yoo JY (2012), Yoo JY (2012), Yoo JY (2012)	3
SUZ12	0	SNW1	0	affinity chromatography technology	Cao Q (2014)	1
EZH2	4	AKT1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Cha TL (2005), Cha TL (2005), Cha TL (2005)	3
KCNA4	5	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Kim SJ (2013), Kim SJ (2013)	2
SNW1	0	RARA	5	two hybrid, affinity chromatography technology	Kang MR (2010), Kang MR (2010)	2
TRIM28	1	PARP1	3	affinity chromatography technology	Quenet D (2008)	1
MDM2	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, protein complementation assay, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, unspecified method, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, biochemical, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, protein complementation assay, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, imaging technique, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, pull down, unspecified method, fluorescent resonance energy transfe, two hybrid, pull down	Li M (2003), Latonen L (2001), Zhang Y (2003), Zhang Y (2003), Kurki S (2003), Kurki S (2003), Freeman DJ (2003), Ito A (2002), Ito A (2002), Grossman SR (1998), Fang S (2000), Liu G (2000), Zhang Y (1998), Zhang Y (1998), Chen J (1993), Thut CJ (1997), Leung KM (2002), Wawrzynow B (2009), Ochocka AM (2009), Chen D (2009), Hedstroem E (2009), Brenkman AB (2008), Qiu W (2008), Qiu W (2008), Zhang Z (2008), Muller P (2008), Colaluca IN (2008), Colaluca IN (2008), Colaluca IN (2008), Tang Y (2008), Tang Y (2008), Lu X (2007), Lukashchuk N (2007), Lukashchuk N (2007), Lee JH (2007), Carter S (2007), Sasaki M (2007), Brooks CL (2007), Li L (2007), Becker K (2007), Zhao BX (2006), Zhao BX (2006), Abida WM (2007), Yang WH (2006), Ma J (2006), Wallace M (2006), Shimizu H (2006), Andrews P (2006), Yang J (2009), Zhu Z (2009), Wang C (2005), Higashitsuji H (2005), Higashitsuji H (2005), Yan C (2005), Vega FM (2004), Dai MS (2004), Dai MS (2004), Groenroos E (2004), Ohkubo S (2006), Sui G (2004), Di Stefano V (2004), Brignone C (2004), Katayama H (2004), Linares LK (2003), OKeefe K (2003), Wang W (2003), Blattner C (2002), Matt T (2004), Matt T (2004), Eyckerman S (2005), Shimizu H (2002), Shimizu H (2002), Migliorini D (2002), Gu J (2001), Sengupta S (2001), Chernov MV (2001), Cross B (2011), Cross B (2011), Cross B (2011), Buschmann T (2001), Nakamura S (2000), Rodriguez MS (2000), Rodriguez MS (2000), Geyer RK (2000), Zaika A (1999), Maki CG (1999), Chen L (2010), Chen L (2010), Lin RK (2010), Fuchs SY (1998), Xirodimas DP (2001), Fuchs SY (1998), Inoue T (2001), Wu L (2011), Du W (2009), Li DQ (2009), Illuzzi JL (2011), Oliver TG (2011), Kim MM (2007), Marchenko ND (2007), Vaseva AV (2009), Vaseva AV (2009), Lai KP (2010), Naderi EH (2011), Zdzalik M (2010), Singh RK (2007), Meng L (2011), Moore L (2007), Kim S (2010), Inoue Y (2011), Fraser JA (2010), Worrall EG (2009), Wu H (2011), Wang KS (2011), Wang KS (2011), Wang KS (2011), Izumi T (2010), Huang YF (2009), Tang J (2006), Tang J (2006), Fu X (2010), Fu X (2010), Shloush J (2011), Yadavilli S (2009), Stevenson LF (2007), Suzuki T (2010), Cheng Q (2009), Kulikov R (2010), Kulikov R (2010), Li L (2010), Li L (2010), Cheng Q (2011), Li D (2011), Nie J (2010), Demma M (2010), Sun XX (2011), Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010), Nishida T (2011), Li M (2011), Li M (2011), Amson R (2011), Amson R (2011), Bhatt P (2011), David Y (2011), Zhang Y (2010), Liu J (2010), Liu J (2010), Song MS (2008), Cummins JM (2004), Kim CK (2010), Kim CK (2010), Yan C (2010), Wang X (2011), Phillips A (2010), Phillips A (2010), Kang HN (2011), Kang HN (2011), Wang X (2004), Sionov RV (2001), Wei S (2012), Camus S (2012), Ding B (2012), Yang Z (2012), Yang Z (2012), Tripathi V (2007), Tripathi V (2007), Dai C (2011), Chen S (2012), Honda R (1997), Kinyamu HK (2003), Zhan C (2012), Zhan C (2012), Lee CW (2010), Zhou X (2012), Bouska A (2008), Wade M (2012), Ferreon JC (2009), Domenici F (2011), Uldrijan S (2007), Uldrijan S (2007), Stad R (2000), Stad R (2000), Banks D (2006), Banks D (2006), Bernal F (2010), Bernal F (2010), Jain AK (2012), Kane SA (2000), Tan Z (2000), Yang Z (2012), Wawrzynow B (2007), Wawrzynow B (2007), Wawrzynow B (2007), Hiramatsu K (2006), Bao-Lei T (2006), Kulikov R (2005), Yang Y (2005), Lindstroem MS (2007), Bech-Otschir D (2001), Li Y (2012), Gillotin S (2010), Burch L (2004), Liu WL (2001), OHagan HM (2004), OHagan HM (2004), Funari G (2009), Candeias MM (2008), Brew CT (2006), Wang J (2011), Calabro V (2002), Burch L (2004), Iyappan S (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Kurki S (2004), Tian LF (2006), Wang J (2006), Bae S (2012), Bae S (2012), Frazier DP (2012), Frazier DP (2012), Lew QJ (2012), Lew QJ (2012), Huart AS (2012), Li Z (2004), Balint E (1999), Balint E (1999), Funston G (2012), Dou X (2012), Sadagopan S (2012), Sadagopan S (2012), Dixit D (2012), Roxburgh P (2012), Xu L (2012), Drago-Ferrante R (2008), Li H (2009), Negorev D (2001), Wang X (2012), Wang X (2012), Wang X (2012), Boettger A (1997), Jung H (2008), Oliner JD (1992), Seemann S (2005), Kawai H (2007), Schuster K (2007), Dawson R (2003), DArcy P (2009), Schon O (2004), Schon O (2004), Hogan C (2008), Lottin-Divoux S (2005), Latini P (2011), Latini P (2011), Latini P (2011), McCoy MA (2003), Kussie PH (1996), Shieh SY (1997), Shieh SY (1997), Naski N (2009), Naski N (2009), Schon O (2002), Tamborini E (2001), Wade M (2006), Wade M (2006), Lohrum MA (2003), Garcia JF (2002), Garcia JF (2002), Kallen J (2009), Kulikov R (2006), Kulikov R (2006), Czarna A (2009), Czarna A (2009), Hu B (2007), Chi SW (2005), Yu GW (2006), Yu GW (2006), Saji S (2001), Chen L (1997), Zhang H (1998), Issaeva N (2004), Wade M (2008), Wade M (2008), Chen HF (2007), Chen HF (2007), Li HH (2004), Wang J (2011), Gu L (2009), Gu L (2009), Meng L (2008), Meng L (2008), Okamoto K (2006), Malaguarnera R (2008), Zhou M (2003), Zhou M (2003), Di Conza G (2012), Xirodimas DP (2004), Auger KR (2005), Li J (2011), Li J (2011), Li J (2011), Lee SJ (2007), Chau JF (2012), Lu X (2005), Mazars A (2010), Mazars A (2010), Mazars A (2010), Olson DC (1993), Picksley SM (1994), Issaeva N (2004), Issaeva N (2004), Zhang J (2012), Wen W (2013), Wen W (2013), Bursac S (2012), Yang Y (2013), Yang Y (2013), Landre V (2013), Pettersson S (2012), Thin TH (2007), Thin TH (2007), Piccinin S (2012), Shan B (2012), Caratozzolo MF (2012), Lui K (2013), Kobet E (2000), Lim KH (2010), Ranaweera RS (2013), Cui D (2013), Ebina M (2013), He Y (2013), He Y (2013), Siepe D (2009), Suh HW (2013), Zhan YA (2013), Wang J (2011), Hjerpe R (2010), Murray MF (2007), Jin L (2013), Jin L (2013), Zhang R (2013), Yan S (2013), Sun XX (2011), Heyne K (2014), Heyne K (2014), Bista M (2013), Jin J (2014), Mikawa T (2014), Qi M (2014), Cheng Q (2014), Zhang HH (2014), Perry ME (2000), Nishizaki M (2004), Sanchez-Aguilera A (2006), Chen YC (2013), Bertamino A (2013), Ding G (2013), Kubo N (2013), Kubo N (2013), Hsueh KW (2013), Kofod-Olsen E (2014), Fogeron ML (2013), Chang YS (2013), Gotoh T (2014), Gotoh T (2014), Oi N (2014), Corcoran CA (2009), Corcoran CA (2009), Ayroldi E (2014), Wu G (2014), Rajendra R (2004), Zhang J (2014), Lee MG (2014), Lee MG (2014), Freedman DA (1997), Freedman DA (1997), Saxena A (2006), Shi D (2009), Lohrum MA (2001), Lohrum MA (2001), Grossman SR (2003), Yan S (2013), Xirodimas DP (2004), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Saville MK (2004), Rodriguez MS (1999), Lui K (2013), Wu PY (2003), Pavithra L (2009), He Y (2013), Tan BX (2014), Huttlin EL (2015), Marcar L (2015), Borcherds W (2014), Borcherds W (2014), Li YC (2014), Ayroldi E (2014), Ling X (2014), Batuello CN (2015), Zhu N (2006), Mo XL (2015), Chen TC (2014), Stindt MH (2015), Caratozzolo MF (2014), Li X (2015), Saxena R (2016), Reed SM (2014), Du C (2016), Du C (2016), Du C (2016), Fraser JA (2015), Fraser JA (2015), Wu B (2015), Qin JJ (2015), Raza S (2015), Raza S (2015), Yamauchi T (2014), Yamauchi T (2014), Yamauchi T (2014), Shi Y (2010), Ahn HJ (2015), Lim KH (2015), Kang JH (2016), Chen J (2015), Liu X (2016), Yang P (2016), Yang P (2016), Liu D (2016), Liu D (2016), Liu D (2016), Datta D (2015), Reddy BA (2014), He X (2016), Shostak K (2014), Liu LJ (2016), Liu LJ (2016), Stegh AH (2010), Liu XH (2005), Medina-Medina I (2016), Medina-Medina I (2016), Kayama K (2017), Singh AK (2016), Liu WT (2016), Yue X (2016), Soares J (2015), Mukhopadhyay R (2016), Mukhopadhyay R (2016), Zhou X (2016), Zhou X (2016), Xie X (2016), Leao M (2015), Luo H (2016), Luo H (2016), Xie N (2016), Maeda R (2017), Maeda R (2017), Maeda R (2017), Sheng W (2017), Sheng W (2017), Liu M (2010), Huttlin EL (2017), Chauhan KM (2016), Goetz C (1999), Zhang J (2017), Unger T (1999), Liu Z (2004), Wu W (2015), Tan G (2017), Nomura K (2017), Lu W (2017), Lu W (2017), Hjerrild M (2001), Landre V (2017), Landre V (2017), Landre V (2017), Landre V (2017), Shangary S (2008), Shangary S (2008), Du WW (2017), Du WW (2017), Bista M (2013), Bista M (2013), Jin M (2017), LaRusch GA (2007), LaRusch GA (2007), Kurokawa M (2013), Ivanov AA (2017), Wong JH (2017), Wong JH (2017)	496
HSP90AA1	7	AKT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Haendeler J (2003), Kawauchi K (2005), Sato S (2000), Basso AD (2002), Su CH (2011), Klein JB (2005), Sun L (2012)	7
JUN	0	HIF1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alfranca A (2002), Yu B (2009), Yu B (2009)	3
SIRT1	3	RICTOR	4	enzymatic study, affinity chromatography technology	Glidden EJ (2012), Singh BK (2016)	2
SIRT1	3	MYC	2	pull down, affinity chromatography technology	Menssen A (2012), Menssen A (2012)	2
SMAD7	1	KAT2B	2	affinity chromatography technology	Monteleone G (2005)	1
EP300	36	FOXO1	2	enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Brent MM (2008), Perrot V (2005), Perrot V (2005), Perrot V (2005), Perrot V (2005), Pramanik KC (2014), Pramanik KC (2014), Mahmud DL (2002), Li X (2015)	9
MAPK8	3	RPTOR	4	affinity chromatography technology, affinity chromatography technology	Kwak D (2012), Kwak D (2012)	2
NDN	0	TP53	0	two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Taniura H (1999), Taniura H (1999), Huang Z (2013), Corominas R (2014), Hasegawa K (2008), Hasegawa K (2008)	6
VDR	2	SNW1	0	two hybrid, pull down, far western blotting, pull down, two hybrid	Baudino TA (1998), Baudino TA (1998), Baudino TA (1998), Zhang C (2001), Zhang C (2001)	5
NCOR1	9	EP300	36	affinity chromatography technology	Cowger JJ (2006)	1
JUN	0	HOXB9	0	affinity chromatography technology	Li X (2015)	1
KAT5	1	MDM2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Legube G (2002), Legube G (2002), Wu Q (2009), Dohmesen C (2008), Dohmesen C (2008), Kim JW (2008)	6
CSNK2A1	15	MAPT	1	enzymatic study	Raftery M (2005)	1
SIRT1	3	STK11	2	enzymatic study, affinity chromatography technology, affinity chromatography technology	Lan F (2008), Lan F (2008), Bai B (2016)	3
KAT2B	2	PARP1	3	enzymatic study	Rajamohan SB (2009)	1
EP300	36	ARNTL	2	pull down	Curtis AM (2004)	1
CSNK2A1	15	STK11	2	genetic interference	Srivas R (2016)	1
PPARGC1A	3	NDN	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Hasegawa K (2016), Hasegawa K (2016), Hasegawa K (2016), Hasegawa K (2016)	4
TSC2	17	AKT1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Dan HC (2002), Roux PP (2004), Dan HC (2002), Dan HC (2002)	4
IRS2	6	SIRT1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology	Zhang J (2007), Zhang J (2007), Froejdoe S (2011)	3
SIRT1	3	JUN	0	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Gao Z (2008), Zhang R (2010), Zhang R (2010), Armour SM (2013)	4
SIRT1	3	DVL2	5	affinity chromatography technology, affinity chromatography technology	Holloway KR (2010), Holloway KR (2010)	2
TP73	2	TRIM28	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Satija YK (2016), Satija YK (2016), Satija YK (2016), Satija YK (2016)	4
CDK1	0	EZH2	4	enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Chen S (2010), Avdic V (2011), Avdic V (2011), Avdic V (2011), Wei Y (2011), Wei Y (2011), Kaneko S (2010), Wan J (2015), Li Z (2017)	9
CHEK2	2	WRN	6	genetic interference	Srivas R (2016)	1
ESRRA	2	KAT2B	2	affinity chromatography technology, enzymatic study	Wilson BJ (2010), Wilson BJ (2010)	2
SFRP4	1	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TP53	0	MTA1	3	pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Yao YL (2003), Li DQ (2010), Moon HE (2007), Moon HE (2007), Li DQ (2009), Li DQ (2009)	6
AR	3	NCOR1	9	two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, imaging technique, genetic interference, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology	Masiello D (2004), Song LN (2004), Cheng S (2002), Cheng S (2002), Cheng S (2002), Hodgson MC (2005), Hodgson MC (2005), Cheng S (2002), Cheng S (2002), Song LN (2004), Wu Y (2006), Wu Y (2006), Fu M (2002), Altintas DM (2011), Cui J (2011), Hodgson MC (2005), Hodgson MC (2005), Zhu P (2006), Qi J (2013), Lempiaeinen JK (2017), Tan G (2017)	21
SIRT1	3	SUZ12	0	affinity chromatography technology, affinity chromatography technology	Kuzmichev A (2005), OHagan HM (2011)	2
EP300	36	FOS	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Wang WM (2011), Pekarsky Y (2008), Wang C (2001)	3
FGF10	0	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
JUN	0	SATB1	1	affinity chromatography technology	Li X (2015)	1
USP22	1	SIRT1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Lin Z (2012), Lin Z (2012), Armour SM (2013), Armour SM (2013), Armour SM (2013), Armour SM (2013), Wang Q (2016), Xiong H (2017), Xiong H (2017), Ling S (2017)	11
MYC	2	USP22	1	imaging technique, affinity chromatography technology, affinity chromatography technology, pull down	Zhang XY (2008), Kim D (2017), Kim D (2017), Kim D (2017)	4
DOT1L	7	BRINP1	5	affinity chromatography technology	Hein MY (2015)	1
KCNAB2	3	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Kim SJ (2013), Kim SJ (2013)	2
FOXO1	2	RARA	5	pull down	Zhao HH (2001)	1
HIF1A	1	TRIM28	1	affinity chromatography technology	Cai Q (2013)	1
CSNK2A1	15	CSNK2B	5	pull down, affinity chromatography technology, far western blotting, two hybrid, two hybrid, two hybrid, pull down, enzymatic study, affinity chromatography technology, two hybrid, enzymatic study, biochemical, far western blotting, far western blotting, x-ray crystallography, enzymatic study, two hybrid, affinity chromatography technology, two hybrid, biochemical, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Kim MS (1998), Kim MS (1998), Marin O (1997), Bosc DG (2000), Ahn BH (2001), Kusk M (1999), Benitez MJ (2001), Uhle S (2003), Olsen BB (2008), Son MY (1999), Son MY (1999), Havugimana PC (2012), Llorens F (2003), Llorens F (2003), Niefind K (2001), Lee NY (2009), Wang J (2011), So J (2015), Wallach T (2013), Wan C (2015), Gao Z (2014), Ren K (2011), Goetz C (1999), Hauri S (2016)	24
CHEK2	2	MDM2	2	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study	Pereg Y (2006), Kass EM (2009), Kass EM (2009), Bjorling-Poulsen M (2005), Bjorling-Poulsen M (2005), Bjorling-Poulsen M (2005), Bjorling-Poulsen M (2005)	7
SIRT1	3	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Zhao W (2008), Liu X (2011), Inoue Y (2011), Jain AK (2012), Langley E (2002), Langley E (2002), Langley E (2002), Kim JE (2008), Kim JE (2008), Kim EJ (2007), Kim EJ (2007), Busch F (2012), Busch F (2012), Hasegawa K (2008), Hasegawa K (2008), Hasegawa K (2008), Zannini L (2012)	17
SIRT1	3	NBN	1	affinity chromatography technology, pull down, enzymatic study	Yuan Z (2007), Yuan Z (2007), Yuan Z (2007)	3
SIRT1	3	RPTOR	4	affinity chromatography technology, affinity chromatography technology	Back JH (2011), Back JH (2011)	2
HEY2	0	SIRT1	3	affinity chromatography technology, pull down	Takata T (2003), Takata T (2003)	2
MYC	2	IRS2	6	genetic interference	Toyoshima M (2012)	1
ZEB1	3	MPHOSPH8	1	affinity chromatography technology	Sun L (2015)	1
SIRT1	3	PARP1	3	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Rajamohan SB (2009), Rajamohan SB (2009), Rajamohan SB (2009), Rajamohan SB (2009)	4
VDR	2	MDM2	2	affinity chromatography technology, affinity chromatography technology	Heyne K (2015), Heyne K (2015)	2
SATB1	1	KAT2B	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study	Pavan Kumar P (2006), Pavan Kumar P (2006), Pavan Kumar P (2006), Pavan Kumar P (2006), Xue Z (2012)	5
MYC	2	FOXO3	1	affinity chromatography technology	Chandramohan V (2008)	1
BRINP1	5	TP53	0	affinity chromatography technology	Qin B (2015)	1
TP53	0	EP300	36	pull down, genetic interference, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, x-ray crystallography, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, unspecified method, affinity chromatography technology, enzymatic study, unspecified method, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, unspecified method	An W (2004), Pastorcic M (2000), Livengood JA (2002), Livengood JA (2002), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Tang Y (2008), Wang H (2008), Valbuena A (2008), Shi D (2009), Vega FM (2004), Finlan L (2004), Groenroos E (2004), Zhao Y (2006), Roe JS (2006), Pedeux R (2005), Sekaric P (2007), Pan X (2009), Tang Y (2006), Sen GS (2011), Li Y (2012), Li Y (2012), Gillotin S (2010), Grossman SR (2003), Issaeva N (2004), Kitagawa M (2008), Sabbatini P (2002), Burge S (2009), Zilfou JT (2001), Issaeva N (2004), Issaeva N (2004), Feng H (2009), Feng H (2009), Lill NL (1997), Dornan D (2004), Dornan D (2004), Di Agostino S (2006), Wells M (2008), Fath DM (2006), Kobet E (2000), Costanzo A (2002), Kumazawa T (2011), Borger DR (2006), Cui D (2013), Borger DR (2006), Lee SJ (2013), Tang HY (2006), Lin C (2011), Choi WI (2014), Ding G (2013), Kim MK (2013), Ali A (2013), Wu G (2014), Mizuguchi Y (2012), Sinha S (2012), Sinha S (2012), Her YR (2013), Her YR (2013), Wu SY (2009), Wu SY (2009), Liu L (1999), Sakaguchi K (1998), Harrod R (2003), Gu W (1997), Teufel DP (2007), Mantovani F (2007), Mantovani F (2007), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), MacPartlin M (2005), Mujtaba S (2004), Wang YH (2003), Chen H (1999), Tang Z (2013), Graczyk A (2013), Graczyk A (2013), Chan HM (2001), Thomas MC (2005), Miller Jenkins LM (2015), Miller Jenkins LM (2015), Koh DI (2014), Koh DI (2014), Koh DI (2014), Li H (2015), Chen LF (2005), Shi D (2016), Wright DG (2016), Zhang X (2016), Procopio MG (2015), Tong Q (2015)	95
PML	7	KAT5	1	affinity chromatography technology, pull down	Wu Q (2009), Wu Q (2009)	2
SUZ12	0	DNMT1	5	affinity chromatography technology	Xu B (2011)	1
TP53	0	KAT5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Legube G (2004), Tyteca S (2006), Tyteca S (2006), Kurash JK (2008), Cheng Z (2008), Cheng Z (2008), Cheng Z (2008), Tang Y (2006), Tang Y (2006), Tang Y (2006), Dai C (2013)	11
PML	7	SUZ12	0	affinity chromatography technology	Villa R (2007)	1
HIC1	1	SIRT1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stankovic-Valentin N (2007), Dehennaut V (2012), Dehennaut V (2012), Chen WY (2005), Dehennaut V (2013)	5
RPS2	3	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
KAT2B	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study	Jin Y (2002), Wang H (2008), Zhao Y (2006), Roe JS (2006), Perez RE (2010), Tang Y (2006), Zhao LY (2003), Liu L (1999), Liu L (1999), Sakaguchi K (1998), Harrod R (2003), Harrod R (2003), MacPartlin M (2005), Chen H (1999), Kang H (2009)	15
MYC	2	CCAR2	9	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Ewing RM (2007), Koch HB (2007), Koch HB (2007), Koch HB (2007), Koch HB (2007), Menssen A (2012)	6
ARNTL	2	CSNK2B	5	two hybrid	Wallach T (2013)	1
MDM2	2	JUN	0	pull down	Miyamoto-Sato E (2010)	1
SNW1	0	NR0B2	1	two hybrid	Albers M (2005)	1
KAT2B	2	E2F1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pediconi N (2009), Ji W (2014), Ianari A (2004), Ianari A (2004), Aoki I (2012)	5
NDN	0	E2F1	0	two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Taniura H (1998), Kuwako K (2004), Kuwako K (2004), Kuwako K (2004), Taniura H (1998), Taniura H (1998)	6
FOXO1	2	SETD7	2	affinity chromatography technology	Li X (2015)	1
TRIM28	1	DNMT1	5	affinity chromatography technology, affinity chromatography technology	Quenneville S (2011), Cui S (2011)	2
MAPK8	3	AKT1	1	enzymatic study	Xiao L (2010)	1
KAT2B	2	CLOCK	0	pull down	Curtis AM (2004)	1
PARP1	3	TP53	0	affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, pull down, pull down	Gueven N (2004), Malanga M (1998), Vaziri H (1997), Vaziri H (1997), Wesierska-Gadek J (2003), Simbulan-Rosenthal CM (2003)	6
MDM2	2	CCAR2	9	affinity chromatography technology	Okoro DR (2013)	1
KAT2B	2	JUN	0	affinity chromatography technology	Tsai LN (2008)	1
JUN	0	ARNTL	2	affinity chromatography technology	Boldt K (2016)	1
DNMT1	5	MTA1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Cui S (2011), Cui S (2011), Cai Y (2014), Cai Y (2014), Wan C (2015)	5
RPL6	0	MDM2	2	affinity chromatography technology, affinity chromatography technology	Bai D (2013), Bai D (2013)	2
SIRT1	3	EPAS1	6	enzymatic study, affinity chromatography technology	Chen R (2012), Chen R (2012)	2
AKT1	1	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Lin WN (2008), Lee IT (2010), Sundaresan NR (2011), Howie HL (2011), Chen J (2004), Chen J (2004)	6
NDN	0	SIRT1	3	affinity chromatography technology, pull down	Hasegawa K (2008), Hasegawa K (2008)	2
MAPK8	3	IRS1	7	two hybrid, affinity chromatography technology, pull down	Aguirre V (2002), Aguirre V (2000), Aguirre V (2000)	3
CTTN	1	EP300	36	affinity chromatography technology	Zhang Y (2009)	1
KAT5	1	TP73	2	affinity chromatography technology	Kim JW (2008)	1
TP53	0	STK11	2	affinity chromatography technology, fluorescent resonance energy transfe	Karuman P (2001), Ivanov AA (2017)	2
CSNK2B	5	TLE1	6	two hybrid	Vinayagam A (2011)	1
RARA	5	PARP1	3	affinity chromatography technology, affinity chromatography technology	Pavri R (2005), Pavri R (2005)	2
SETD7	2	AR	3	affinity chromatography technology	Ko S (2011)	1
VDR	2	FOXO3	1	affinity chromatography technology, affinity chromatography technology, pull down	An BS (2010), An BS (2010), An BS (2010)	3
SMAD7	1	AKT1	1	affinity chromatography technology	Song K (2006)	1
FOXO1	2	SIRT1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kitamura YI (2005), Bastien-Dionne PO (2011), Yang Y (2005), Yang Y (2005)	4
EP300	36	EPAS1	6	pull down, affinity chromatography technology, affinity chromatography technology	Kung AL (2004), Steunou AL (2012), Chen R (2012)	3
SNW1	0	HSP90AA1	7	affinity chromatography technology	Lleres D (2010)	1
RARA	5	SUV39H1	0	affinity chromatography technology	Carbone R (2006)	1
MYCN	2	PRMT1	3	pull down, enzymatic study, affinity chromatography technology	Eberhardt A (2016), Eberhardt A (2016), Eberhardt A (2016)	3
EPAS1	6	NDN	0	affinity chromatography technology, affinity chromatography technology, pull down	Huang Z (2013), Huang Z (2013), Huang Z (2013)	3
EZH2	4	DNMT1	5	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vire E (2006), Vire E (2006), Vire E (2006), Xu B (2011), OHagan HM (2011)	5
EP300	36	SNW1	0	pull down	Leong GM (2004)	1
TP53	0	PML	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Kurki S (2003), Kurki S (2003), Fogal V (2000), Fogal V (2000), Guo A (2000), Guo A (2000), Insinga A (2004), Chu Y (2011), Li Q (2011), Li Q (2011), Bernassola F (2005), Yang Q (2013), Yang Q (2013), Catalano A (2004), Chen TC (2014)	15
SIRT1	3	SMAD7	1	affinity chromatography technology, affinity chromatography technology, pull down	Kume S (2007), Kume S (2007), Kume S (2007)	3
FOS	0	JUN	0	pull down, two hybrid, pull down, x-ray crystallography, two hybrid, pull down, two hybrid, two hybrid, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, fluorescent resonance energy transfe, pull down, pull down, imaging technique, pull down, affinity chromatography technology, pull down, pull down, fluorescent resonance energy transfe, pull down, pull down, affinity chromatography technology, biochemical, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ito T (2001), Pognonec P (1997), Pognonec P (1997), Glover JN (1995), Yang X (1999), Nomura N (1993), Finkel T (1993), Finkel T (1993), Venugopal R (1998), Kumar NV (2001), Dumin E (2006), Bandyopadhyay S (2010), Asim M (2010), Asim M (2010), Srivastav RK (2011), Bossis G (2005), Bossis G (2005), Gupta K (2000), Bachmann M (2004), Reinke AW (2013), Miyagi M (2005), Subbaramaiah K (2007), Jang M (2012), Yamaguchi K (2005), Varjosalo M (2013), Miyamoto-Sato E (2010), Miyamoto-Sato E (2010), Varjosalo M (2013), Tang HY (2006), Marden NY (2005), Adler J (2010), Adler J (2010), Adler J (2010), Billiet L (2008), Huttlin EL (2015), Hein MY (2015), Li X (2015), Li X (2015), Huttlin EL (2017)	39
SIRT1	3	FOS	0	pull down, enzymatic study	Zhang R (2010), Zhang R (2010)	2
SIRT1	3	NR1H4	0	pull down, enzymatic study	Kemper JK (2009), Kemper JK (2009)	2
SIRT1	3	TRIM28	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Lin Z (2012), Lin YH (2015), Lin YH (2015), Lin YH (2015)	4
KAT8	2	CCAR2	9	affinity chromatography technology	Sharma GG (2010)	1
AKT1	1	GAPDH	0	affinity chromatography technology	Klein JB (2005)	1
JUN	0	HSP90AA1	7	two hybrid, pull down	Bandyopadhyay S (2010), Miyamoto-Sato E (2010)	2
SIRT1	3	SNW1	0	two hybrid, pull down, affinity chromatography technology	Kang MR (2010), Kang MR (2010), Kang MR (2010)	3
RARA	5	AKT1	1	affinity chromatography technology, enzymatic study, pull down	Srinivas H (2006), Srinivas H (2006), Srinivas H (2006)	3
CCAR2	9	SIRT1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Magni M (2014), Magni M (2014), Menssen A (2012), Zannini L (2012), Zannini L (2012)	5
MDM2	2	MTA1	3	affinity chromatography technology, affinity chromatography technology	Li DQ (2009), Li DQ (2009)	2
VDR	2	NR0B2	1	two hybrid	Albers M (2005)	1
KAT2B	2	MECOM	4	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Chakraborty S (2001), Chakraborty S (2001), Shimahara A (2010), Shimahara A (2010)	4
NR0B2	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, imaging technique	Yang Z (2012), Yang Z (2012), Yang Z (2012)	3
PML	7	RARA	5	pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhong S (1999), Zhong S (1999), Minucci S (2000), Kraemer OH (2008), Wang K (2010), Wang K (2010), Cote S (2000), Bellodi C (2006), Villa R (2007)	9
ARNTL	2	EPAS1	6	two hybrid, pull down	Hogenesch JB (1998), Hogenesch JB (1998)	2
PSME3	0	CCAR2	9	affinity chromatography technology, affinity chromatography technology	Magni M (2014), Magni M (2014)	2
SUZ12	0	PRMT1	3	affinity chromatography technology	Cao Q (2014)	1
KAT5	1	NBN	1	affinity chromatography technology	Chailleux C (2010)	1
SIRT1	3	ARNTL	2	affinity chromatography technology, enzymatic study	Nakahata Y (2008), Nakahata Y (2008)	2
PPARGC1A	3	EP300	36	affinity chromatography technology	Cooper MP (2006)	1
AKT1	1	RPTOR	4	affinity chromatography technology	Kim EK (2011)	1
SETD7	2	TP53	0	enzymatic study, enzymatic study, x-ray crystallography, two hybrid	Huang J (2006), Chuikov S (2004), Chuikov S (2004), Wang J (2011)	4
NR1H4	0	PRMT1	3	affinity chromatography technology	Rizzo G (2005)	1
HES1	0	HSP90AA1	7	affinity chromatography technology	Tremblay CS (2008)	1
CSNK2A1	15	CDK1	0	enzymatic study	Russo GL (1992)	1
CDK1	0	E2F1	0	enzymatic study	Dynlacht BD (1997)	1
SIRT1	3	TULP3	0	affinity chromatography technology, affinity chromatography technology	Armour SM (2013), Huttlin EL (2017)	2
AR	3	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Dai Y (2008), Minges JT (2013), Zhong J (2014), Fu M (2000), McClurg UL (2016), Tan G (2017)	6
MDM2	2	SUZ12	0	affinity chromatography technology, affinity chromatography technology	Wienken M (2016), Wienken M (2016)	2
HSP90AA1	7	GAPDH	0	affinity chromatography technology, biochemical	Falsone SF (2005), Wan C (2015)	2
EP300	36	SMAD7	1	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Groenroos E (2002), Groenroos E (2002), Groenroos E (2002), Groenroos E (2002)	4
GAPDH	0	KAT5	1	two hybrid	Goehler H (2004)	1
KAT2B	2	MYC	2	enzymatic study	Patel JH (2004)	1
HDAC4	10	NCOR1	9	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, affinity chromatography technology	Fischle W (2002), Fischle W (2002), Fischle W (2002), Huang EY (2000), Huang EY (2000), Huang EY (2000), Wen YD (2000), Wen YD (2000), Joshi P (2013)	9
EZH2	4	SUZ12	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Su IH (2005), Aoto T (2008), Hansen KH (2008), Li G (2010), Margueron R (2008), Margueron R (2008), Shen X (2008), Pasini D (2008), Pasini D (2008), Sarma K (2008), Xu B (2011), Xu B (2011), Avdic V (2011), Kaneko S (2010), Kaneko S (2010), Yap DB (2011), Lee ST (2011), Havugimana PC (2012), Sahasrabuddhe AA (2014), Wang L (2013), Wu L (2013), Pasini D (2010), Pasini D (2010), Pasini D (2010), Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014), Wan C (2015), Hein MY (2015), Bhatnagar S (2014), Bhatnagar S (2014), Zhao R (2015), Wienken M (2016), Huttlin EL (2017), Zhang H (2016), Zhang H (2016), Mahara S (2016), Hauri S (2016), Hauri S (2016)	40
SIRT1	3	BRINP1	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhao W (2008), Zhao W (2008), Chini CC (2010), Close P (2012), Armour SM (2013), Kim JE (2008), Kim JE (2008), Kim JE (2008)	8
IRS1	7	IRS2	6	biochemical	Sun H (2003)	1
NR0B2	1	AR	3	pull down, two hybrid, pull down	Gobinet J (2001), Gobinet J (2001), Obendorf M (2007)	3
SNW1	0	CTTN	1	affinity chromatography technology	Lleres D (2010)	1
E2F1	0	KAT2A	1	affinity chromatography technology	Lang SE (2001)	1
E2F1	0	KAT5	1	affinity chromatography technology, affinity chromatography technology	Taubert S (2004), Taubert S (2004)	2
EP300	36	ZEB1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Mizuguchi Y (2012), Postigo AA (2003), Postigo AA (2003), Postigo AA (2003)	4
TP73	2	KAT2B	2	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhao LY (2003), Zhao LY (2003), Zhao LY (2003), Zhao LY (2003), Hoffmann A (2008)	5
CDK1	0	KAT5	1	enzymatic study	Lemercier C (2003)	1
HES1	0	TLE1	6	pull down, affinity chromatography technology, affinity chromatography technology	Buscarlet M (2008), Tremblay CS (2009), Tremblay CS (2009)	3
PPARGC1A	3	KAT2A	1	affinity chromatography technology	Rodrigue-Way A (2013)	1
HERC2	9	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Cubillos-Rojas M (2014), Cubillos-Rojas M (2014), Cubillos-Rojas M (2014), Bai B (2016)	4
CWC15	0	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MDM2	2	GAPDH	0	affinity chromatography technology	Frum R (2007)	1
VDR	2	SIRT1	3	affinity chromatography technology, pull down	An BS (2010), An BS (2010)	2
SUV39H1	0	MECOM	4	affinity chromatography technology, pull down, affinity chromatography technology	Cattaneo F (2008), Cattaneo F (2008), Spensberger D (2008)	3
PML	7	MDM2	2	affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bernardi R (2004), Bernardi R (2004), Zhu H (2003), Zhu H (2003), Kurki S (2003), Kurki S (2003), Wei X (2003), Wei X (2003), Wu Q (2009), Chu Y (2011), Yang Q (2013), Yang Q (2013), Bursac S (2012)	13
CSNK2A1	15	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study	Uhle S (2003), Fogeron ML (2013), Bhansali M (2014), Chen TC (2014), Walerych D (2004), Walerych D (2004)	6
MDM2	2	AKT1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique	Lin HK (2002), Ogawara Y (2002), Zhou BP (2001), Zhou BP (2001), Kim CK (2011), Kim CK (2011), Zhu QS (2011), Milne D (2004), Deep G (2008), Deep G (2008), Chen TC (2014)	11
ESRRA	2	PPARGC1A	3	x-ray crystallography, two hybrid, pull down	Kallen J (2004), Huss JM (2002), Huss JM (2002)	3
AKT1	1	FOXO3	1	enzymatic study, imaging technique	Sundaresan NR (2011), Chen TC (2014)	2
KAT2A	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
IRS1	7	DVL2	5	affinity chromatography technology, affinity chromatography technology	Geng Y (2014), Geng Y (2014)	2
HEY2	0	NCOR1	9	affinity chromatography technology, pull down	Iso T (2001), Iso T (2001)	2
KAT2A	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
VDR	2	EP300	36	imaging technique, imaging technique	Kim S (2005), Kim S (2005)	2
MDM2	2	TP73	2	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Balint E (1999), Zeng X (1999), Zeng X (1999), Chen L (2010), Zdzalik M (2010), Kim JW (2008), Balint E (1999), Balint E (1999), Wang J (2011), Ongkeko WM (1999), Ongkeko WM (1999), Ongkeko WM (1999), Ongkeko WM (1999), Wu H (2015), Stindt MH (2015), Zhou X (2015), Zhou X (2015)	17
MAPK8	3	HSP90AA1	7	affinity chromatography technology	Nieto-Miguel T (2008)	1
SIRT1	3	TP73	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Dai JM (2007), Dai JM (2007), Dai JM (2007)	3
IRS2	6	RPTOR	4	pull down	Tzatsos A (2009)	1
HIF1A	1	NBN	1	affinity chromatography technology, affinity chromatography technology, pull down	Kuo YC (2015), Kuo YC (2015), Kuo YC (2015)	3
CSNK2A1	15	MYCN	2	enzymatic study	Hagiwara T (1992)	1
SREBF1	5	TADA2B	3	affinity chromatography technology	Ebmeier CC (2010)	1
FOS	0	CSNK2A1	15	pull down, far western blotting	Yamaguchi Y (1998), Yamaguchi Y (1998)	2
EZH2	4	TLE1	6	affinity chromatography technology, affinity chromatography technology	Su L (2012), Su L (2012)	2
SIRT1	3	KAT8	2	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Lu L (2011), Lu L (2011), Lu L (2011), Peng L (2012)	4
MDM2	2	E2F1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhang Z (2005), Zhang Z (2005), Stevens C (2008), Stevens C (2008)	4
ESRRA	2	SIRT1	3	pull down, enzymatic study	Wilson BJ (2010), Wilson BJ (2010)	2
HOXB9	0	SIRT1	3	affinity chromatography technology, pull down	Wan J (2016), Wan J (2016)	2
RARA	5	SIRT1	3	affinity chromatography technology, pull down	Kang MR (2010), Kang MR (2010)	2
PML	7	NCOR1	9	pull down, affinity chromatography technology, two hybrid, pull down	Khan MM (2001), Khan MM (2001), Khan MM (2001), Minucci S (2000)	4
EP300	36	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Bouras T (2005), Bourguignon LY (2009)	2
IRS1	7	MTOR	14	affinity chromatography technology, affinity chromatography technology, enzymatic study	Ozes ON (2001), Tzatsos A (2006), Tzatsos A (2006)	3
KAT5	1	MYC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Frank SR (2003), Frank SR (2003), Liu T (2007), Liu T (2007), Kim J (2010), Kim J (2010)	6
NCOR1	9	NR1H4	0	affinity chromatography technology	Li CW (2009)	1
MDM2	2	SETD7	2	pull down	Lezina L (2015)	1
MYC	2	TRIM28	1	affinity chromatography technology	Koch HB (2007)	1
HIF1A	1	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Chen D (2003), Ravi R (2000), Hansson LO (2002), An WG (1998), An WG (1998), Chowdhury AR (2017), Chowdhury AR (2017), Suzuki H (2001), Sanchez-Puig N (2005)	9
CSNK2A1	15	TP73	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Lu H (2014), Lu H (2014), Lu H (2014)	3
KAT8	2	TP53	0	enzymatic study, enzymatic study, pull down	Sykes SM (2006), Li X (2009), Dou Y (2005)	3
BCL11A	14	MTA1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cismasiu VB (2005), Huttlin EL (2015), Huttlin EL (2017)	3
PML	7	SATB1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Kumar PP (2007), Kumar PP (2007), Kumar PP (2007), Kumar PP (2007), Tan JA (2008)	5
MYC	2	MDM2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHFR	5	SIRT1	3	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Kim M (2016), Kim M (2016), Kim M (2016), Kim M (2016)	4
SNW1	0	NCOR1	9	two hybrid, pull down, pull down	Leong GM (2004), Leong GM (2004), Leong GM (2004)	3
MDM2	2	HSP90AA1	7	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, biochemical, unspecified method, affinity chromatography technology	Lu TL (2010), Burch L (2004), Burch L (2004), Burch L (2004), Burch L (2004), Burch LR (2004), Okoro DR (2013)	7
EPAS1	6	JUN	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
TP53	0	GAPDH	0	affinity chromatography technology	Sen N (2008)	1
HIC1	1	MECOM	4	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Pradhan AK (2014), Pradhan AK (2014), Pradhan AK (2014)	3
CHEK2	2	PSME3	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zannini L (2009), Zannini L (2009), Magni M (2014)	3
CSNK2A1	15	RPL6	0	enzymatic study	Zhang M (2011)	1
VDR	2	TP53	0	affinity chromatography technology, affinity chromatography technology	Stambolsky P (2010), Stambolsky P (2010)	2
SUZ12	0	CSNK2B	5	affinity chromatography technology	Cao Q (2014)	1
MDM2	2	BRINP1	5	unspecified method	Nicholson J (2014)	1
MDM2	2	FOXO3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fu W (2009), Fu W (2009), Yang JY (2008), Yang JY (2008), Du WW (2017), Du WW (2017), Du WW (2017), Du WW (2017)	8
MTOR	14	RICTOR	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jacinto E (2004), Jacinto E (2004), Sarbassov DD (2004), Sarbassov DD (2004), Sarbassov DD (2004), Frias MA (2006), Jacinto E (2006), Yang Q (2006), Frias MA (2006), Sarbassov DD (2006), Sarbassov DD (2005), Yang Q (2006), Kaizuka T (2010), Pearce LR (2007), Oh WJ (2010), Oh WJ (2010), Agrawal P (2012), Guo Z (2012), Sarbassov DD (2006), Sancak Y (2007), Yang Q (2006), Jacinto E (2006), Jacinto E (2006), Rosner M (2010), Ikenoue T (2008), Ikenoue T (2008), Murata H (2011), Murata H (2011), Koike-Kumagai M (2009), Koike-Kumagai M (2009), Woods NT (2012), Hussain S (2013), Peterson TR (2009), Peterson TR (2009), Su WC (2009), Hernandez-Negrete I (2007), Ramirez-Rangel I (2011), Martin J (2008), Martin J (2008), Martin J (2008), Thedieck K (2007), Thedieck K (2007), Thedieck K (2007), McDonald PC (2008), McDonald PC (2008), Hong F (2008), Hong F (2008), Facchinetti V (2008), Toschi A (2009), Zhang F (2010), Chen CH (2011), Chen CH (2011), Xu Y (2013), Xu Y (2013), Glidden EJ (2012), Glidden EJ (2012), Vander Haar E (2007), Koo J (2015), Thedieck K (2007)	59
RARA	5	EP300	36	affinity chromatography technology, affinity chromatography technology	Subbaramaiah K (2002), Reineke EL (2007)	2
SIRT1	3	SREBF1	5	enzymatic study, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Walker AK (2010), Ponugoti B (2010), Ponugoti B (2010), Ponugoti B (2010), Ponugoti B (2010)	5
HSP90AA1	7	KAT5	1	affinity chromatography technology	Taipale M (2012)	1
MDM2	2	HIF1A	1	pull down, affinity chromatography technology, enzymatic study, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Chen D (2003), Chen D (2003), Ravi R (2000), Lee YM (2009), Lee YM (2009), Lee YM (2009), Maroni P (2014), Amelio I (2015), Yoo YG (2004), LaRusch GA (2007), LaRusch GA (2007), Nieminen AL (2005)	12
SNW1	0	MYC	2	affinity chromatography technology, affinity chromatography technology	Bres V (2009), Bres V (2009)	2
PARP1	3	JUN	0	affinity chromatography technology	Kim BK (2014)	1
CDK1	0	PML	7	enzymatic study	Yuan WC (2011)	1
TP73	2	EP300	36	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Strano S (2005), Uramoto H (2004), Zeng X (2000), Zeng X (2000), Zeng X (2000), Zeng X (2000), Zeng X (2000), Mantovani F (2004), Burge S (2009), Burge S (2009), Costanzo A (2002), Hoffmann A (2008), Kramer D (2015)	13
RARA	5	MDM2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Ying M (2016), Ying M (2016), Ying M (2016)	3
STK11	2	DVL2	5	affinity chromatography technology	Huttlin EL (2017)	1
CSNK2B	5	MDM2	2	enzymatic study	Goetz C (1999)	1
EZH2	4	SIRT1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Kuzmichev A (2005), Kuzmichev A (2005), OHagan HM (2011), Wan J (2015), Wan J (2015), Wan J (2015)	6
USP22	1	TADA2B	3	affinity chromatography technology	Sowa ME (2009)	1
MTA1	3	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CLOCK	0	ARNTL	2	two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Ooe N (2004), McNamara P (2001), McNamara P (2001), Hogenesch JB (1998), Hosoda H (2009), Alhopuro P (2010), Wallach T (2013), Wallach T (2013), Lee Y (2015), Huttlin EL (2017), Boldt K (2016)	11
TP53	0	APEX1	1	biochemical, affinity chromatography technology	Jayaraman L (1997), Seemann S (2005)	2
DVL2	5	TP53	0	two hybrid, two hybrid	Rual JF (2005), Lim J (2006)	2
DVL2	5	CSNK2A1	15	affinity chromatography technology	Song DH (2000)	1
PRMT1	3	AR	3	pull down	Koh SS (2001)	1
MYC	2	PML	7	affinity chromatography technology, affinity chromatography technology, pull down	Cairo S (2005), Buschbeck M (2007), Buschbeck M (2007)	3
RICTOR	4	AKT1	1	enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, enzymatic study	Sarbassov DD (2006), Sarbassov DD (2005), Ikenoue T (2008), Murata H (2011), Woods NT (2012), Kim EK (2011), Chen CH (2011), Garcia-Martinez JM (2009), Chen TC (2014), Pitre A (2012)	10
KCNA5	2	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Kim SJ (2013), Kim SJ (2013)	2
PML	7	PSME3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zannini L (2009), Huttlin EL (2015), Huttlin EL (2017)	3
HES1	0	SIRT1	3	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Takata T (2003), Takata T (2003), Takata T (2003), Takata T (2003)	4
HIC1	1	SUZ12	0	affinity chromatography technology	Boulay G (2012)	1
RARA	5	HDAC4	10	pull down	Franco PJ (2003)	1
HSP90AA1	7	AR	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Veldscholte J (1992), Nemoto T (1992), Zoubeidi A (2007), DaSilva J (2009), Chymkowitch P (2011), Gibbs A (2009), Wolf SS (2007), Luo J (2015), Kwegyir-Afful AK (2015), Ni L (2010), McClurg UL (2016)	11
KAT5	1	DNMT1	5	affinity chromatography technology	Du Z (2010)	1
MAPK8	3	MYC	2	enzymatic study, pull down, affinity chromatography technology	Noguchi K (1999), Noguchi K (1999), Noguchi K (1999)	3
HIF1A	1	RPTOR	4	affinity chromatography technology	Land SC (2007)	1
DNMT1	5	HIC1	1	affinity chromatography technology, affinity chromatography technology	Zeng S (2016), Zeng S (2016)	2
WRN	6	NBN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cheng WH (2005), Kobayashi J (2010), Kobayashi J (2010)	3
MYC	2	TP53	0	affinity chromatography technology, fluorescent resonance energy transfe	Agrawal P (2010), Ivanov AA (2017)	2
TRIM28	1	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Doyle JM (2010), Gilmore-Hebert M (2010), Okamoto K (2006)	3
EP300	36	SREBF1	5	affinity chromatography technology, affinity chromatography technology, pull down, biochemical, pull down, affinity chromatography technology, enzymatic study	Sundqvist A (2003), Giandomenico V (2003), Giandomenico V (2003), Naeaer AM (1999), Naeaer AM (1999), Ebmeier CC (2010), Ponugoti B (2010)	7
NBN	1	RICTOR	4	affinity chromatography technology, affinity chromatography technology	Wang JQ (2013), Wang JQ (2013)	2
EZH2	4	SUV39H1	0	affinity chromatography technology, two hybrid	Weimann M (2013), Weimann M (2013)	2
PML	7	SIRT1	3	affinity chromatography technology, pull down	Langley E (2002), Langley E (2002)	2
MYC	2	HIF1A	1	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Koshiji M (2004), Koshiji M (2004), Ivanov AA (2017)	3
AR	3	FOXO1	2	affinity chromatography technology, two hybrid, far western blotting	Li P (2003), Li P (2003), Li P (2003)	3
MTA1	3	EP300	36	affinity chromatography technology	Gururaj AE (2006)	1
FOXO1	2	MDM2	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Fu W (2009), Fu W (2009), Fu W (2009), Fu W (2009), Jang H (2016)	5
CDK1	0	TP53	0	enzymatic study, affinity chromatography technology	Luciani MG (2000), Ababneh M (2001)	2
NCOR1	9	TRIM28	1	biochemical, affinity chromatography technology	Underhill C (2000), Nomura T (2004)	2
DNMT1	5	PARP1	3	affinity chromatography technology	Cai Y (2014)	1
PPARGC1A	3	PML	7	affinity chromatography technology, affinity chromatography technology	Gao J (2015), Gao J (2015)	2
TP53	0	FOXO3	1	imaging technique, affinity chromatography technology, affinity chromatography technology	Chen TC (2014), Du WW (2017), Du WW (2017)	3
MYC	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RPL6	0	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
AR	3	TP53	0	genetic interference	Shenk JL (2001)	1
BRINP1	5	SUV39H1	0	affinity chromatography technology	Li Z (2009)	1
EP300	36	MAPT	1	enzymatic study	Min SW (2010)	1
EPAS1	6	HIF1A	1	affinity chromatography technology	Steunou AL (2012)	1
VDR	2	JUN	0	pull down	Towers TL (1999)	1
TP53	0	RPS2	3	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
NR0B2	1	SIRT1	3	pull down, affinity chromatography technology, affinity chromatography technology	Chanda D (2010), Chanda D (2010), Chanda D (2010)	3
NR0B2	1	RARA	5	pull down, two hybrid, pull down	Seol W (1996), Seol W (1998), Seol W (1998)	3
MYC	2	VDR	2	affinity chromatography technology	Salehi-Tabar R (2012)	1
ZEB1	3	KAT5	1	two hybrid	Hlubek F (2001)	1
EP300	36	KAT5	1	affinity chromatography technology, affinity chromatography technology	Col E (2005), Col E (2005)	2
SETD7	2	SMAD7	1	enzymatic study	Elkouris M (2016)	1
MECOM	4	PRMT1	3	two hybrid	Weimann M (2013)	1
GAPDH	0	HES1	0	two hybrid	Vinayagam A (2011)	1
EP300	36	NR1H4	0	enzymatic study	Kemper JK (2009)	1
CHFR	5	PARP1	3	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kashima L (2012), Kashima L (2012), Ahel I (2008), Oh YM (2009), Liu C (2013), Brodie SA (2015), Brodie SA (2015)	7
AKT1	1	MTOR	14	pull down, unspecified method, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, imaging technique, enzymatic study, imaging technique	Sekulic A (2000), Cheng SW (2004), Oh WJ (2010), Sarbassov DD (2005), Ikenoue T (2008), Murata H (2011), Martin J (2008), Facchinetti V (2008), Facchinetti V (2008), Chen CH (2011), Xu Y (2013), Glidden EJ (2012), Chen TC (2014), Pitre A (2012), Moon HE (2015)	15
SIRT1	3	GAPDH	0	affinity chromatography technology, pull down	Kornberg MD (2010), Kornberg MD (2010)	2
KAT2B	2	ARNTL	2	pull down	Curtis AM (2004)	1
SIRT1	3	RPS19BP1	0	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Armour SM (2013), Kim EJ (2007), Kim EJ (2007), Kim EJ (2007), Kim EJ (2007)	5
IRS2	6	MTOR	14	affinity chromatography technology	Warren KJ (2016)	1
SIRT1	3	KAT2A	1	affinity chromatography technology, affinity chromatography technology	Lin Z (2012), Armour SM (2013)	2
TP73	2	HIF1A	1	affinity chromatography technology	Amelio I (2015)	1
RARA	5	CLOCK	0	two hybrid, pull down, pull down	McNamara P (2001), McNamara P (2001), McNamara P (2001)	3
SIRT1	3	TLE1	6	two hybrid, affinity chromatography technology	Ghosh HS (2007), Ghosh HS (2007)	2
RARA	5	E2F1	0	affinity chromatography technology, pull down	Zhang L (2014), Zhang L (2014)	2
NDN	0	TRIM28	1	affinity chromatography technology	Doyle JM (2010)	1
AKT1	1	MAPT	1	enzymatic study	Sadik G (2009)	1
EP300	36	NBN	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Jung SY (2005), Jang ER (2011), Jang ER (2011)	3
MAPK8	3	TP53	0	affinity chromatography technology, pull down, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down	Hu MC (1997), Yin ZM (2004), Yin ZM (2004), Fuchs SY (1998), Topisirovic I (2009), Drago-Ferrante R (2008), Wang J (2000), Chang NS (2003), Fuchs SY (1998)	9
PARP1	3	HIF1A	1	affinity chromatography technology	Elser M (2008)	1
SIRT1	3	KAT2B	2	enzymatic study, affinity chromatography technology, affinity chromatography technology	Pediconi N (2009), Pediconi N (2009), Pediconi N (2009)	3
HIF1A	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHEK2	2	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Magni M (2014), Magni M (2014)	2
FOXO1	2	SATB1	1	affinity chromatography technology	Li X (2015)	1
TADA2B	3	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PML	7	JUN	0	pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Vallian S (1998), Yasuda S (1999), Salomoni P (2005), Salomoni P (2005), Seo SR (2006), Seo SR (2006), Seo SR (2006)	7
PPARGC1A	3	PPARA	1	pull down	Vega RB (2000)	1
CSNK2B	5	EZH2	4	two hybrid	Wallach T (2013)	1
SNW1	0	NBN	1	affinity chromatography technology	Lleres D (2010)	1
EZH2	4	TRIM28	1	affinity chromatography technology	Cao Q (2014)	1
SIRT1	3	CTTN	1	affinity chromatography technology, pull down, enzymatic study	Zhang Y (2009), Zhang Y (2009), Zhang Y (2009)	3
IRS1	7	AKT1	1	affinity chromatography technology, enzymatic study	Paz K (1999), Luo M (2007)	2
CHEK2	2	CCAR2	9	affinity chromatography technology, affinity chromatography technology	Magni M (2014), Magni M (2014)	2
TULP3	0	PML	7	affinity chromatography technology	Huttlin EL (2017)	1
SMAD7	1	ZEB1	3	affinity chromatography technology, affinity chromatography technology, pull down	Nakahata S (2010), Nakahata S (2010), Nakahata S (2010)	3
CSNK2A1	15	MYC	2	enzymatic study	Channavajhala P (2002)	1
HIF1A	1	HDAC4	10	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid	Seo HW (2009), Seo HW (2009), Qian DZ (2006), Bodily JM (2011), Kato H (2004)	5
PPARA	1	PRMT1	3	two hybrid	Weimann M (2013)	1
WRN	6	PARP1	3	affinity chromatography technology, pull down, affinity chromatography technology	Li B (2004), Li B (2004), Li B (2004)	3
WRN	6	TP53	0	affinity chromatography technology, pull down, pull down	Yang Q (2002), Yang Q (2002), Brosh RM (2001)	3
MTA1	3	JUN	0	pull down	Li DQ (2011)	1
EP300	36	PRMT1	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Hassa PO (2008), Lai Y (2017), Lai Y (2017)	3
SIRT1	3	AKT1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Sundaresan NR (2011), Sundaresan NR (2011), Sundaresan NR (2011)	3
SIRT1	3	AR	3	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Fu M (2006), Fu M (2006), Fu M (2006), Fu M (2006)	4
TP53	0	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TSC2	17	FOXO1	2	affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Cao Y (2006), Cao Y (2006), Cao Y (2006), Cao Y (2006)	4
VDR	2	FOS	0	pull down	Towers TL (1999)	1
MTOR	14	EP300	36	enzymatic study	Wan W (2017)	1
SUZ12	0	ACACA	5	affinity chromatography technology	Cao Q (2014)	1
AR	3	MDM2	2	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zoubeidi A (2007), Gaughan L (2005), Gaughan L (2005), Chymkowitch P (2011), Chymkowitch P (2011), Liu T (2012), Liu T (2012), Deep G (2008), Deep G (2008), Lin HK (2002), Lin HK (2002), Zhang A (2015), Kwegyir-Afful AK (2015), McClurg UL (2016), McClurg UL (2016), Liao Y (2017), Steely AM (2017), Zhai W (2016)	18
APEX1	1	HIF1A	1	pull down	Carrero P (2000)	1
CDK1	0	USP22	1	affinity chromatography technology	Lin Z (2015)	1
TP53	0	KAT2A	1	affinity chromatography technology, fluorescent resonance energy transfe	Gamper AM (2008), Ivanov AA (2017)	2
MAPK8	3	MTOR	14	affinity chromatography technology	Kwak D (2012)	1
EP300	36	HIF1A	1	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down	Lando D (2002), Freedman SJ (2002), Lewis MD (2004), Matt T (2004), Sang N (2002), Luo W (2010), Freedman SJ (2003), Bodily JM (2011), Lee YM (2009), Lee YM (2009), Lee YM (2009), Kung AL (2004), Kung AL (2004), Kung AL (2004), Land SC (2007), Zhang Y (2010), Zhang Y (2010), Fath DM (2006), Fath DM (2006), Lee SJ (2013), Wang D (2014), Kaluz S (2006), Kaluz S (2006), Kaluz S (2006), Shin DH (2008), Shin DH (2008), Wang Y (2012), Huang C (2009), Hewitson KS (2002), Cook KM (2009), Cook KM (2009), Hubbi ME (2012), Kim SY (2014), Sang N (2003), Sang N (2003), Sang N (2003), Yasinska IM (2003), Na YR (2013), Na YR (2013), Mendonca DB (2011), Arany Z (1996), Arany Z (1996), Chen R (2012), Li SH (2008), Galbraith MD (2013), Chen Z (2014), Li Q (2012), Geng H (2012), Geng H (2012), Kato H (2004), Lim JH (2010), Kyle HF (2015), Kyle HF (2015), Rath S (2016), Kimura M (2008), Dubey R (2013)	56
MYC	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SIRT1	3	APEX1	1	enzymatic study, affinity chromatography technology, affinity chromatography technology	Yamamori T (2010), Yamamori T (2010), Yamamori T (2010)	3
STK11	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nony P (2003), Brajenovic M (2004), Gaude H (2012), Taipale M (2012), Huttlin EL (2017)	5
AR	3	KAT2B	2	pull down, enzymatic study	Fu M (2000), Fu M (2000)	2
EZH2	4	RARA	5	affinity chromatography technology	Villa R (2007)	1
HSP90AA1	7	ARNTL	2	pull down	Hogenesch JB (1997)	1
TP53	0	SNW1	0	affinity chromatography technology	Fogeron ML (2013)	1
RPTOR	4	RICTOR	4	affinity chromatography technology, affinity chromatography technology	Rosner M (2010), Rosner M (2010)	2
JUN	0	AR	3	affinity chromatography technology, affinity chromatography technology	Sato N (1997), Sato N (1997)	2
NDN	0	HIF1A	1	affinity chromatography technology, two hybrid	Moon HE (2005), Moon HE (2005)	2
NBN	1	MTOR	14	affinity chromatography technology, affinity chromatography technology	Wang JQ (2013), Wang JQ (2013)	2
MYC	2	NCOR1	9	genetic interference	Kessler JD (2012)	1
HSP90AA1	7	CSNK2A1	15	pull down, enzymatic study, enzymatic study, affinity chromatography technology	Miyata Y (1995), Muller P (2012), Zhang M (2011), Woo SH (2009)	4
PML	7	CSNK2B	5	affinity chromatography technology	Sivachandran N (2010)	1
SIRT1	3	CSNK2B	5	affinity chromatography technology, affinity chromatography technology, pull down	Jang SY (2011), Jang SY (2011), Jang SY (2011)	3
PARP1	3	PRMT1	3	affinity chromatography technology, affinity chromatography technology	Hassa PO (2008), Hassa PO (2008)	2
KAT2B	2	HNF1A	0	affinity chromatography technology, pull down	Soutoglou E (2000), Soutoglou E (2000)	2
MDM2	2	NBN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alt JR (2005), Alt JR (2005), Bouska A (2008)	3
TRIM28	1	E2F1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang C (2007), Hu C (2012), Hu C (2012)	3
CHEK2	2	TRIM28	1	affinity chromatography technology	Hu C (2012)	1
SUZ12	0	MTOR	14	affinity chromatography technology	Cao Q (2014)	1
EP300	36	JUN	0	pull down, biochemical, x-ray crystallography, affinity chromatography technology, pull down, enzymatic study, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Campbell KM (2002), Campbell KM (2002), Campbell KM (2002), Subbaramaiah K (2002), Duyndam MC (1999), Wang WM (2011), Deng WG (2004), Deng WG (2004), Cheng SE (2011), Cheng SE (2011), Kim BK (2014), Vries RG (2001), Deng WG (2003), Liu L (2017), Liu L (2017)	15
FOXO3	1	SIRT1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	van der Horst A (2004), van der Horst A (2004), An BS (2010), An BS (2010), Tseng PC (2011), Brunet A (2004), Brunet A (2004), Brunet A (2004)	8
SUZ12	0	MTA1	3	affinity chromatography technology	Cao Q (2014)	1
HOXB5	0	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CCAR2	9	KCNAB2	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SIRT1	3	MPHOSPH8	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Sun L (2015), Sun L (2015), Sun L (2015)	3
PML	7	MTOR	14	affinity chromatography technology	Bernardi R (2006)	1
SIRT1	3	MECOM	4	affinity chromatography technology, affinity chromatography technology	Pradhan AK (2011), Pradhan AK (2011)	2
ESRRA	2	NR0B2	1	two hybrid	Albers M (2005)	1
MAPT	1	SIRT1	3	pull down, affinity chromatography technology	Min SW (2010), Min SW (2010)	2
EP300	36	MDM2	2	pull down, affinity chromatography technology, biochemical, pull down, pull down, enzymatic study, affinity chromatography technology, biochemical, enzymatic study	Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Matt T (2004), Wang X (2004), Gillotin S (2010), Kobet E (2000), Nihira NT (2017)	9
APEX1	1	EP300	36	affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, enzymatic study, pull down	Sengupta S (2011), Sengupta S (2011), Sengupta S (2011), Sengupta S (2011), Bhakat KK (2003), Yamamori T (2010), Karmakar S (2010)	7
KAT2B	2	EZH2	4	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Wan J (2015), Wan J (2015), Wan J (2015), Wan J (2015), Wan J (2015)	5
KAT2B	2	HIF1A	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Bodily JM (2011), Geng H (2012), Geng H (2012), Lim JH (2010)	4
RARA	5	NCOR1	9	two hybrid, pull down, pull down, two hybrid, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, far western blotting, affinity chromatography technology, two hybrid, pull down, pull down, pull down	Dowell P (1999), Dowell P (1999), Guidez F (1998), Guidez F (1998), Li CW (2009), Loinder K (2004), Loinder K (2004), Minucci S (2000), Grignani F (1998), Grignani F (1998), DiRenzo J (1997), Zhu P (2006), Wang J (2011), Hoerlein AJ (1995), DiRenzo J (1997), DiRenzo J (1997)	16
PPARGC1A	3	NR1H4	0	pull down, affinity chromatography technology	Zhang Y (2004), Zhang Y (2004)	2
PARP1	3	FOXO1	2	affinity chromatography technology, affinity chromatography technology, pull down	Sakamaki J (2009), Sakamaki J (2009), Sakamaki J (2009)	3
MDM2	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EZH2	4	AR	3	affinity chromatography technology	Cao Q (2014)	1
SMAD7	1	MYC	2	affinity chromatography technology, affinity chromatography technology	Kim TA (2013), Kim TA (2013)	2
KAT2B	2	HOXB9	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Wan J (2016), Wan J (2016), Wan J (2016), Wan J (2016), Wan J (2016)	5
SUZ12	0	TRIM28	1	affinity chromatography technology	Cao Q (2014)	1
RARA	5	KAT2B	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hu X (2004), Korzus E (1998), Reineke EL (2007)	3
HNF1A	0	FOS	0	affinity chromatography technology	Leu JI (2001)	1
SIRT1	3	E2F1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Pediconi N (2009), Ji W (2014), Wang C (2006), Wang C (2006)	4
PML	7	CSNK2A1	15	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Rabellino A (2012), Stehmeier P (2009), Hung MS (2010), Hung MS (2010), Scaglioni PP (2006)	5
KCNA5	2	KCNA4	5	affinity chromatography technology	Nitabach MN (2001)	1
PPARA	1	HSP90AA1	7	affinity chromatography technology, pull down, two hybrid	Sumanasekera WK (2003), Sumanasekera WK (2003), Sumanasekera WK (2003)	3
ZBTB38	5	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SIRT1	3	SUV39H1	0	affinity chromatography technology, affinity chromatography technology	Li Z (2009), Vaquero A (2007)	2
MYC	2	SUV39H1	0	genetic interference, affinity chromatography technology	Toyoshima M (2012), Hauri S (2016)	2
MTOR	14	TP53	0	affinity chromatography technology, genetic interference	Su WC (2009), Ye H (2016)	2
TP53	0	NCOR1	9	affinity chromatography technology, imaging technique	Dohi Y (2008), Ali A (2013)	2
EP300	36	HNF1A	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Ban N (2002), Ban N (2002), Dohda T (2004), Dohda T (2004)	4