Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
LY96 23643 DODECANOATE CHEMBL108766 DrugBank 10592235
LY96 23643 MYRISTIC ACID CHEMBL111077 DrugBank 10592235
LY96 23643 ERITORAN TETRASODIUM (CHEMBL3301672) CHEMBL3301672 antagonist ChemblInteractions
LY96 23643 CHEMBL1232858 CHEMBL1232858 DrugBank 10592235

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
LY96 rs11465996 CG + GG Tumor necrosis factor alpha efficacy yes Good responders (those with a reduction of >=75% in PASI score after 3 months) were compared against non-responders (those with a reduction of <50% in PASI score after 3 months). Statistical results adjusted for age, gender, psoriatic arthritis and previous treatments and corrected for multiple testing using the false discovery rate. Genotypes CG + GG is associated with decreased response to Tumor necrosis factor alpha (TNF-alpha) inhibitors in people with Psoriasis as compared to genotype CC. 28696418 1449155414