Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
GABRA5 2558 THIOPENTAL CHEMBL441 potentiator TdgClinicalTrial, TEND, DrugBank 11264449, 10209232
GABRA5 2558 FLUMAZENIL CHEMBL407 antagonist, allosteric modulator TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, TEND, DrugBank 19907641
GABRA5 2558 CHEMBL34155 CHEMBL34155 agonist GuideToPharmacologyInteractions
GABRA5 2558 CHEMBL200177 CHEMBL200177 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 BRETAZENIL CHEMBL366947 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 ZINC ION CHEMBL1236970 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 METHADONE CHEMBL651 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 T-BUTYLBICYCLOPHOSPHOROTHIONATE CHEMBL485673 channel blocker GuideToPharmacologyInteractions
GABRA5 2558 HEXOBARBITAL CHEMBL7728 potentiator TdgClinicalTrial, TEND, DrugBank 11264449, 10209232
GABRA5 2558 FLUDIAZEPAM CHEMBL13291 potentiator TdgClinicalTrial, TEND, DrugBank 2857046
GABRA5 2558 CLOBAZAM CHEMBL70418 positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND
GABRA5 2558 CHLORDIAZEPOXIDE CHEMBL451 positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND
GABRA5 2558 CHLORDIAZEPOXIDE HYDROCHLORIDE CHEMBL1200703 positive allosteric modulator ChemblInteractions
GABRA5 2558 GLUTETHIMIDE CHEMBL1102 ChemblInteractions
GABRA5 2558 LORAZEPAM CHEMBL580 positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND
GABRA5 2558 PENTOBARBITAL CHEMBL448 positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND
GABRA5 2558 PENTOBARBITAL SODIUM CHEMBL971 positive allosteric modulator ChemblInteractions
GABRA5 2558 THIAMYLAL SODIUM CHEMBL1201065 positive allosteric modulator ChemblInteractions
GABRA5 2558 HALOTHANE CHEMBL931 positive allosteric modulator ChemblInteractions
GABRA5 2558 TEMAZEPAM CHEMBL967 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 18384456, 20138190
GABRA5 2558 SECOBARBITAL CHEMBL447 potentiator TdgClinicalTrial, TEND, DrugBank 11264449, 10209232
GABRA5 2558 PRIMIDONE CHEMBL856 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 11264449, 10209232
GABRA5 2558 GABOXADOL CHEMBL312443 agonist TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions
GABRA5 2558 ISONIPECOTIC ACID CHEMBL279998 agonist GuideToPharmacologyInteractions
GABRA5 2558 MUSCIMOL CHEMBL273481 agonist GuideToPharmacologyInteractions
GABRA5 2558 CHEMBL1518572 CHEMBL1518572 agonist GuideToPharmacologyInteractions
GABRA5 2558 CHEMBL70176 CHEMBL70176 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 RO-194603 CHEMBL269366 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 ALPRAZOLAM CHEMBL661 allosteric modulator, positive allosteric modulator TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, TEND
GABRA5 2558 BICUCULLINE CHEMBL417990 antagonist GuideToPharmacologyInteractions
GABRA5 2558 PICROTOXIN CHEMBL1908342 channel blocker GuideToPharmacologyInteractions
GABRA5 2558 AMOBARBITAL CHEMBL267894 potentiator DrugBank 11264449, 10209232
GABRA5 2558 HEPTABARBITAL CHEMBL468837 potentiator DrugBank 11264449, 10209232
GABRA5 2558 CLOTIAZEPAM CHEMBL1697737 potentiator TdgClinicalTrial, TEND, DrugBank 18855614
GABRA5 2558 QUAZEPAM CHEMBL1200472 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 3017690, 2892106
GABRA5 2558 CLONAZEPAM CHEMBL452 positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND
GABRA5 2558 METHOHEXITAL SODIUM CHEMBL30219 positive allosteric modulator ChemblInteractions
GABRA5 2558 MIDAZOLAM HYDROCHLORIDE CHEMBL1200420 positive allosteric modulator ChemblInteractions
GABRA5 2558 PROPOFOL CHEMBL526 positive allosteric modulator ChemblInteractions
GABRA5 2558 PF-06372865 CHEMBL3707402 agonist ChemblInteractions
GABRA5 2558 PHENOBARBITAL CHEMBL40 TdgClinicalTrial, TEND
GABRA5 2558 BUTABARBITAL CHEMBL449 TdgClinicalTrial, TEND
GABRA5 2558 CLORAZEPIC ACID CHEMBL1213252 TdgClinicalTrial, TEND
GABRA5 2558 CLORAZEPATE DIPOTASSIUM CHEMBL2096631 positive allosteric modulator ChemblInteractions
GABRA5 2558 DESFLURANE CHEMBL1200733 positive allosteric modulator ChemblInteractions
GABRA5 2558 ACAMPROSATE CALCIUM CHEMBL2068724 ChemblInteractions
GABRA5 2558 TALBUTAL CHEMBL1200802 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 11264449, 10209232
GABRA5 2558 MEPROBAMATE CHEMBL979 agonist TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 19244096, 9067327
GABRA5 2558 ESZOPICLONE CHEMBL1522 agonist, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, DrugBank 18973287, 19942638
GABRA5 2558 METHARBITAL CHEMBL450 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 11264449, 10209232
GABRA5 2558 HALAZEPAM CHEMBL970 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 2867566, 6738302
GABRA5 2558 DIAZEPAM CHEMBL12 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 18384456, 11752090, 15009644
GABRA5 2558 OXAZEPAM CHEMBL568 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 18384456, 11752090
GABRA5 2558 MEPHOBARBITAL CHEMBL45029 potentiator DrugBank 11264449, 10209232, 21194017
GABRA5 2558 TRIAZOLAM CHEMBL646 potentiator, allosteric modulator, positive allosteric modulator TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, TEND, DrugBank 18384456, 11752090
GABRA5 2558 ZOPICLONE CHEMBL135400 potentiator TdgClinicalTrial, TEND, DrugBank 18973287, 6135616, 19942638, 20303942
GABRA5 2558 ESTAZOLAM CHEMBL285674 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 2889803, 639854
GABRA5 2558 OCINAPLON CHEMBL2105199 allosteric modulator TdgClinicalTrial, GuideToPharmacologyInteractions
GABRA5 2558 ISOGUVACINE CHEMBL39071 agonist GuideToPharmacologyInteractions
GABRA5 2558 FLUNITRAZEPAM CHEMBL13280 potentiator, allosteric modulator TdgClinicalTrial, GuideToPharmacologyInteractions, TEND, DrugBank 20638393, 17139284, 17016423, 20858465
GABRA5 2558 CHEMBL363211 CHEMBL363211 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 CHEMBL274866 CHEMBL274866 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 CHEMBL58757 CHEMBL58757 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 CHEMBL373250 CHEMBL373250 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 BUTETHAL CHEMBL404422 potentiator TdgClinicalTrial, TEND, DrugBank 11264449, 10209232
GABRA5 2558 PRAZEPAM CHEMBL969 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 7773620
GABRA5 2558 METHOXYFLURANE CHEMBL1341 ChemblInteractions
GABRA5 2558 METHYPRYLON CHEMBL1200790 positive allosteric modulator ChemblInteractions
GABRA5 2558 ISOFLURANE CHEMBL1256 positive allosteric modulator ChemblInteractions
GABRA5 2558 TOPIRAMATE CHEMBL220492 ChemblInteractions
GABRA5 2558 RESEQUINIL CHEMBL2107801 inverse agonist ChemblInteractions
GABRA5 2558 MIDAZOLAM CHEMBL655 TdgClinicalTrial, TEND
GABRA5 2558 SECOBARBITAL SODIUM CHEMBL1200903 positive allosteric modulator ChemblInteractions
GABRA5 2558 TRICLOFOS SODIUM CHEMBL1200789 ChemblInteractions
GABRA5 2558 Lorediplon CHEMBL3707317 positive allosteric modulator ChemblInteractions
GABRA5 2558 BUTALBITAL CHEMBL454 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 11264449, 10209232
GABRA5 2558 ADINAZOLAM CHEMBL328250 potentiator TdgClinicalTrial, TEND, DrugBank 6148400, 6320036
GABRA5 2558 CGS-8216 CHEMBL19732 agonist GuideToPharmacologyInteractions
GABRA5 2558 CHEMBL302715 CHEMBL302715 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 CHEMBL17468 CHEMBL17468 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 CHEMBL52030 CHEMBL52030 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 CHEMBL1080588 CHEMBL1080588 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 METHOCTRAMINE CHEMBL27673 allosteric modulator GuideToPharmacologyInteractions
GABRA5 2558 GABAZINE CHEMBL32503 antagonist GuideToPharmacologyInteractions
GABRA5 2558 APROBARBITAL CHEMBL7863 potentiator DrugBank 11264449, 10209232
GABRA5 2558 BARBITAL CHEMBL444 potentiator DrugBank 11264449, 10209232
GABRA5 2558 BROMAZEPAM CHEMBL277062 potentiator TdgClinicalTrial, TEND, DrugBank 18384456
GABRA5 2558 CINOLAZEPAM CHEMBL2104926 potentiator TdgClinicalTrial, TEND, DrugBank 7849137
GABRA5 2558 NITRAZEPAM CHEMBL13209 potentiator TdgClinicalTrial, TEND, DrugBank 18384456, 11752090
GABRA5 2558 GANAXOLONE CHEMBL1568698 TdgClinicalTrial, DrugBank
GABRA5 2558 BUTABARBITAL SODIUM CHEMBL1200982 positive allosteric modulator ChemblInteractions
GABRA5 2558 ETHCHLORVYNOL CHEMBL591 ChemblInteractions
GABRA5 2558 SEVOFLURANE CHEMBL1200694 positive allosteric modulator ChemblInteractions
GABRA5 2558 THIOPENTAL SODIUM CHEMBL738 positive allosteric modulator ChemblInteractions
GABRA5 2558 ETOMIDATE CHEMBL681 ChemblInteractions
GABRA5 2558 FLURAZEPAM HYDROCHLORIDE CHEMBL1200602 positive allosteric modulator ChemblInteractions
GABRA5 2558 ADIPIPLON CHEMBL2103791 partial agonist TdgClinicalTrial, ChemblInteractions
GABRA5 2558 FLURAZEPAM CHEMBL968 TdgClinicalTrial, TEND
GABRA5 2558 ENFLURANE CHEMBL1257 ChemblInteractions

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID