PPI network (data source: BioGrid)

Symbol A GeneA coding DNM count Symbol B GeneB coding DNM count Interaction detection method Publication Evidence
AP2B1 3 AP2M1 5 two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology Rual JF (2005), Brehme M (2009), Li J (2013), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017) 6
GAK 5 AP2A2 3 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 DBN1 1 affinity chromatography technology Emdal KB (2015) 1
DBN1 1 CLTB 0 affinity chromatography technology Hein MY (2015) 1
CLTC 12 AAK1 4 affinity chromatography technology Hein MY (2015) 1
CLINT1 1 CLTCL1 4 affinity chromatography technology Huttlin EL (2017) 1
SYNPO 5 DAB2 1 affinity chromatography technology Hein MY (2015) 1
GAK 5 WNK1 7 affinity chromatography technology Hein MY (2015) 1
MYO6 3 PIK3C2A 7 affinity chromatography technology Wollscheid HP (2016) 1
SYNPO 5 MYO1C 5 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
ATP13A2 1 HSPA8 4 two hybrid, affinity chromatography technology Usenovic M (2012), Usenovic M (2012) 2
LIMA1 4 MYO1C 5 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
MYO1C 5 CALM1 0 affinity chromatography technology Hein MY (2015) 1
SP1 0 MYO6 3 affinity chromatography technology Chuang JY (2012) 1
C5AR2 1 GAK 5 affinity chromatography technology Huttlin EL (2017) 1
GTSE1 3 DENND1A 2 affinity chromatography technology Hein MY (2015) 1
MYO6 3 EPS15 1 affinity chromatography technology Wollscheid HP (2016) 1
DBN1 1 XPR1 3 affinity chromatography technology Hein MY (2015) 1
TRIM25 5 RABGEF1 1 affinity chromatography technology Choudhury NR (2017) 1
NTRK1 1 HIP1R 5 affinity chromatography technology Emdal KB (2015) 1
DBN1 1 AP2A1 1 affinity chromatography technology Hein MY (2015) 1
STAMBPL1 2 PICALM 0 affinity chromatography technology Huttlin EL (2017) 1
SYNPO 5 MISP 4 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 STON2 2 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 AP2M1 5 affinity chromatography technology Hein MY (2015) 1
APP 1 HSPA8 4 affinity chromatography technology Yamamoto YH (2010) 1
DBN1 1 SPTAN1 9 biochemical, affinity chromatography technology Havugimana PC (2012), Hein MY (2015) 2
CLTA 1 CLTC 12 biochemical, affinity chromatography technology Wan C (2015), Hein MY (2015) 2
CLTB 0 AP2A1 1 affinity chromatography technology Hein MY (2015) 1
CLTC 12 FAM83B 0 affinity chromatography technology Hein MY (2015) 1
SEC24C 2 APP 1 pull down Olah J (2011) 1
GAK 5 CLTB 0 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
DAB2 1 CPSF7 4 affinity chromatography technology Mulkearns EE (2012) 1
GTSE1 3 FAM83B 0 affinity chromatography technology Hein MY (2015) 1
IARS2 2 GAK 5 affinity chromatography technology Huttlin EL (2017) 1
HSPBP1 0 CLTCL1 4 affinity chromatography technology Huttlin EL (2017) 1
MYO6 3 AP2A2 3 affinity chromatography technology Wollscheid HP (2016) 1
GAK 5 ACTRT1 0 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 PICALM 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015), Huttlin EL (2017) 3
GTSE1 3 FAM83H 6 affinity chromatography technology Hein MY (2015) 1
SYNPO 5 AFAP1 3 affinity chromatography technology Hein MY (2015) 1
SYNPO 5 AP2A1 1 affinity chromatography technology Hein MY (2015) 1
SYNPO 5 EPS15 1 affinity chromatography technology Hein MY (2015) 1
LIMA1 4 DENND1A 2 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Boldt K (2016) 2
MYO1C 5 MISP 4 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 LIMA1 4 affinity chromatography technology Emdal KB (2015) 1
DBN1 1 STON2 2 affinity chromatography technology Hein MY (2015) 1
ALK 8 MYO6 3 affinity chromatography technology Ambrogio C (2005) 1
LIMA1 4 AP2A1 1 affinity chromatography technology Hein MY (2015) 1
GAK 5 PSMA5 0 affinity chromatography technology Hein MY (2015) 1
CLTC 12 HIP1R 5 affinity chromatography technology, pull down Hein MY (2015), Legendre-Guillemin V (2002) 2
STON2 2 EPS15 1 two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology Martina JA (2001), Martina JA (2001), Martina JA (2001), Brehme M (2009), Rumpf J (2008), Rumpf J (2008), Rumpf J (2008), Rumpf J (2008) 8
GAK 5 USO1 1 two hybrid Rual JF (2005) 1
TRIM25 5 AXIN1 1 affinity chromatography technology Choudhury NR (2017) 1
MYO6 3 AP2A1 1 affinity chromatography technology, pull down, affinity chromatography technology Buss F (2001), Buss F (2001), Wollscheid HP (2016) 3
GPX7 0 GAK 5 affinity chromatography technology Huttlin EL (2017) 1
SEC16A 7 SEC13 0 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Huttlin EL (2017) 2
NTRK1 1 AP2A2 3 affinity chromatography technology Emdal KB (2015) 1
DBN1 1 AP2B1 3 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 PHGDH 4 affinity chromatography technology Hein MY (2015) 1
LIMA1 4 EPS15 1 affinity chromatography technology Hein MY (2015) 1
PICALM 0 BMP2K 0 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Huttlin EL (2017) 2
NTRK1 1 CLTC 12 affinity chromatography technology Emdal KB (2015) 1
STAMBPL1 2 STAMBP 2 affinity chromatography technology Huttlin EL (2017) 1
HIP1R 5 PPM1B 2 affinity chromatography technology Huttlin EL (2017) 1
CLTB 0 STON2 2 affinity chromatography technology Hein MY (2015) 1
TRIM25 5 APP 1 affinity chromatography technology Choudhury NR (2017) 1
GAK 5 MISP 4 affinity chromatography technology Hein MY (2015) 1
GAK 5 CLINT1 1 affinity chromatography technology Hein MY (2015) 1
GAK 5 SP1 0 affinity chromatography technology Hein MY (2015) 1
PICALM 0 STON2 2 affinity chromatography technology Hein MY (2015) 1
DMWD 3 CAPZB 2 affinity chromatography technology Sowa ME (2009) 1
STAMBPL1 2 EPS15 1 affinity chromatography technology Huttlin EL (2017) 1
DBN1 1 CLINT1 1 affinity chromatography technology Hein MY (2015) 1
CLINT1 1 AP2A2 3 affinity chromatography technology Huttlin EL (2017) 1
TRIM25 5 AP2A1 1 affinity chromatography technology Choudhury NR (2017) 1
CLTC 12 AP2A2 3 pull down, two hybrid, affinity chromatography technology McMahon HT (1997), Knuehl C (2006), Hein MY (2015) 3
GAK 5 INF2 5 affinity chromatography technology Hein MY (2015) 1
CLTB 0 CLINT1 1 affinity chromatography technology Hein MY (2015) 1
DBN1 1 NUMB 1 affinity chromatography technology Hein MY (2015) 1
SEC16A 7 RBM14 5 affinity chromatography technology Hein MY (2015) 1
MYO1C 5 DBN1 1 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
GTSE1 3 BMP2K 0 affinity chromatography technology Hein MY (2015) 1
GAK 5 NUMB 1 affinity chromatography technology Hein MY (2015) 1
GAK 5 EPS15 1 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 HIP1 4 affinity chromatography technology Emdal KB (2015) 1
GTSE1 3 CLTA 1 affinity chromatography technology Hein MY (2015) 1
SYNPO 5 CPM 2 affinity chromatography technology Hein MY (2015) 1
CALM1 0 CLINT1 1 pull down Shen X (2005) 1
CLTB 0 EPS15 1 affinity chromatography technology Hein MY (2015) 1
GAK 5 CALM1 0 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 SEC24C 2 affinity chromatography technology Emdal KB (2015) 1
LIMA1 4 PIK3C2A 7 affinity chromatography technology Hein MY (2015) 1
CLTB 0 DAB2 1 affinity chromatography technology Hein MY (2015) 1
CLTC 12 SEC24C 2 affinity chromatography technology Hein MY (2015) 1
LIMA1 4 CLTC 12 affinity chromatography technology Hein MY (2015) 1
TNK2 7 NTRK1 1 affinity chromatography technology, affinity chromatography technology La Torre A (2013), La Torre A (2013) 2
GAK 5 SPTAN1 9 affinity chromatography technology Hein MY (2015) 1
NUMB 1 APP 1 pull down, imaging technique Olah J (2011), Chen TC (2014) 2
GAK 5 CDK5 0 affinity chromatography technology Kanaoka Y (1997) 1
DBN1 1 PICALM 0 affinity chromatography technology Hein MY (2015) 1
SYNPO 5 CEP162 3 affinity chromatography technology Hein MY (2015) 1
FAM83H 6 SEC16A 7 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
DMWD 3 FEM1B 1 affinity chromatography technology Huttlin EL (2015) 1
AP2M1 5 AP2A1 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology Brehme M (2009), Li J (2013), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017) 5
DBN1 1 BMP2K 0 affinity chromatography technology Hein MY (2015) 1
GAK 5 DAB2 1 affinity chromatography technology Hein MY (2015) 1
GAK 5 CAPZB 2 affinity chromatography technology Hein MY (2015) 1
LIMA1 4 CLTA 1 affinity chromatography technology Hein MY (2015) 1
LGR4 3 GAK 5 affinity chromatography technology Carmon KS (2014) 1
GTSE1 3 CLTB 0 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
STAMBP 2 CLINT1 1 affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Huttlin EL (2017) 2
TRIM25 5 DMWD 3 affinity chromatography technology Choudhury NR (2017) 1
TRIM25 5 SPTAN1 9 affinity chromatography technology Choudhury NR (2017) 1
HIP1 4 CLTC 12 affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology Rao DS (2001), Waelter S (2001), Ybe JA (2009), Hein MY (2015), Chen TC (2014), Legendre-Guillemin V (2002), Ames HM (2013) 7
LIMA1 4 APP 1 pull down Olah J (2011) 1
SYNPO 5 SPTAN1 9 affinity chromatography technology Hein MY (2015) 1
CLTC 12 XPR1 3 affinity chromatography technology Hein MY (2015) 1
LGR4 3 CLTCL1 4 affinity chromatography technology Carmon KS (2014) 1
PIK3C2A 7 CLTA 1 biochemical Wan C (2015) 1
PSMA5 0 SEC24C 2 biochemical Havugimana PC (2012) 1
DAB2 1 AP2B1 3 affinity chromatography technology Mulkearns EE (2012) 1
CLASRP 1 GAK 5 affinity chromatography technology Huttlin EL (2017) 1
GAK 5 AFAP1 3 affinity chromatography technology Hein MY (2015) 1
GAK 5 AAK1 4 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 SPTAN1 9 affinity chromatography technology Emdal KB (2015) 1
GAK 5 LIMA1 4 affinity chromatography technology Hein MY (2015) 1
DBN1 1 DAB2 1 affinity chromatography technology Hein MY (2015) 1
LIMA1 4 AP2B1 3 affinity chromatography technology Hein MY (2015) 1
CLTB 0 CLTCL1 4 biochemical, affinity chromatography technology Wan C (2015), Hein MY (2015) 2
CLTC 12 RBM14 5 affinity chromatography technology Hein MY (2015) 1
LIMA1 4 CAPZB 2 affinity chromatography technology Hein MY (2015) 1
SEC16A 7 CLTCL1 4 affinity chromatography technology Hein MY (2015) 1
GAK 5 HIP1 4 affinity chromatography technology Hein MY (2015) 1
LIMA1 4 PICALM 0 affinity chromatography technology Hein MY (2015) 1
CLTB 0 PIK3C2A 7 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 CLTC 12 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
EPS15 1 AP2B1 3 affinity chromatography technology Brehme M (2009) 1
EPS15 1 AP2M1 5 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Brehme M (2009), Brehme M (2009), Li J (2013), Huttlin EL (2015), Huttlin EL (2017) 5
AXIN1 1 GAK 5 two hybrid Stelzl U (2005) 1
PICALM 0 PIK3C2A 7 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Huttlin EL (2017) 2
GAK 5 CEP162 3 affinity chromatography technology Hein MY (2015) 1
CLTB 0 FAM83B 0 affinity chromatography technology Hein MY (2015) 1
CLTB 0 SEC13 0 affinity chromatography technology Hein MY (2015) 1
TRIM25 5 INF2 5 affinity chromatography technology Choudhury NR (2017) 1
SP1 0 MYO1C 5 affinity chromatography technology Chuang JY (2012) 1
DBN1 1 MYO6 3 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 AP2A2 3 affinity chromatography technology Hein MY (2015) 1
LIMA1 4 SPTAN1 9 affinity chromatography technology Hein MY (2015) 1
AP2A1 1 AP2A2 3 biochemical Havugimana PC (2012) 1
NTRK1 1 EPS15 1 affinity chromatography technology Emdal KB (2015) 1
GAK 5 PUS7L 0 affinity chromatography technology Hein MY (2015) 1
GAK 5 KIDINS220 4 affinity chromatography technology Hein MY (2015) 1
TRIM25 5 MISP 4 affinity chromatography technology Choudhury NR (2017) 1
GAK 5 STAMBPL1 2 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Huttlin EL (2017) 2
CLTC 12 CLTB 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015), Zlatic SA (2011) 3
GTSE1 3 PIK3C2A 7 affinity chromatography technology Hein MY (2015) 1
CLINT1 1 EPS15 1 pull down Kalthoff C (2002) 1
MYO6 3 DAB2 1 two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, pull down, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, pull down Morris SM (2002), Inoue A (2002), Morris SM (2002), Morris SM (2002), Morris SM (2002), Morris SM (2002), Inoue A (2002), Inoue A (2002), Sahlender DA (2005), Puri C (2010), Inoue T (2008), Spudich G (2007), Mulkearns EE (2012), Phichith D (2009) 14
AP2M1 5 BMP2K 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Brehme M (2009), Huttlin EL (2015), Huttlin EL (2017) 3
NTRK1 1 PIK3C2A 7 affinity chromatography technology Emdal KB (2015) 1
STAMBPL1 2 CLTC 12 affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology Nakamura M (2006), Nakamura M (2006), Hein MY (2015), Huttlin EL (2017) 4
GTSE1 3 TNK1 0 affinity chromatography technology Hein MY (2015) 1
MYO1C 5 CEP162 3 affinity chromatography technology Hein MY (2015) 1
GAK 5 TNK1 0 affinity chromatography technology Hein MY (2015) 1
LIMA1 4 AP2M1 5 affinity chromatography technology Hein MY (2015) 1
SYNPO 5 SEC16A 7 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 KIDINS220 4 affinity chromatography technology Emdal KB (2015) 1
PHKG2 2 GAK 5 affinity chromatography technology Hein MY (2015) 1
STAMBP 2 PIK3C2A 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Huttlin EL (2015), Huttlin EL (2017) 3
GTSE1 3 AP2A1 1 affinity chromatography technology Hein MY (2015) 1
GAK 5 AP2A1 1 affinity chromatography technology Hein MY (2015) 1
CLTC 12 KIDINS220 4 affinity chromatography technology Hein MY (2015) 1
TRIM25 5 HSPA8 4 affinity chromatography technology, affinity chromatography technology Choudhury NR (2017), Choudhury NR (2017) 2
LIMA1 4 CLTCL1 4 affinity chromatography technology Hein MY (2015) 1
CDK5 0 APP 1 pull down Olah J (2011) 1
TRIM25 5 CAPZB 2 affinity chromatography technology Choudhury NR (2017) 1
HSPA8 4 HSPBP1 0 two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology Rual JF (2005), Stelzl U (2005), Alberti S (2004), Taipale M (2014), Taipale M (2014), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017) 8
DBN1 1 MISP 4 affinity chromatography technology Hein MY (2015) 1
LGR4 3 CLTC 12 affinity chromatography technology Carmon KS (2014) 1
SYNPO 5 CLINT1 1 affinity chromatography technology Hein MY (2015) 1
KIF3A 4 APP 1 pull down, pull down Olah J (2011), Virok DP (2011) 2
GAK 5 STON2 2 affinity chromatography technology Hein MY (2015) 1
GAK 5 CPSF7 4 affinity chromatography technology Hein MY (2015) 1
ALK 8 GAK 5 affinity chromatography technology Crockett DK (2004) 1
STAMBPL1 2 ZNF106 2 affinity chromatography technology Huttlin EL (2017) 1
HSPA8 4 SP1 0 affinity chromatography technology Li L (2013) 1
GAK 5 SYNPO 5 affinity chromatography technology Hein MY (2015) 1
LIMA1 4 CALM1 0 affinity chromatography technology Hein MY (2015) 1
DBN1 1 AP2M1 5 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 IARS2 2 affinity chromatography technology Emdal KB (2015) 1
FBXW7 2 TRIM25 5 two hybrid Arroyo R (2015) 1
TNK2 7 CLTA 1 affinity chromatography technology Chan W (2009) 1
GTSE1 3 DAB2 1 affinity chromatography technology Hein MY (2015) 1
CLTB 0 AP2B1 3 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 AAK1 4 affinity chromatography technology Hein MY (2015) 1
AP2M1 5 HSPA8 4 affinity chromatography technology, affinity chromatography technology Brehme M (2009), Li J (2013) 2
DBN1 1 AFAP1 3 affinity chromatography technology Hein MY (2015) 1
CLTC 12 CLTCL1 4 affinity chromatography technology Hein MY (2015) 1
SEC16A 7 TNK1 0 affinity chromatography technology Hein MY (2015) 1
EPS15 1 BMP2K 0 affinity chromatography technology Brehme M (2009) 1
AP2M1 5 AP2A2 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology Brehme M (2009), Li J (2013), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017) 5
FAM174A 2 GAK 5 affinity chromatography technology Huttlin EL (2017) 1
GAK 5 PLXNA3 5 affinity chromatography technology Hein MY (2015) 1
GAK 5 MYO1C 5 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 SEC13 0 affinity chromatography technology Hein MY (2015) 1
CLTC 12 FAM83H 6 affinity chromatography technology Hein MY (2015) 1
LIMA1 4 CLTB 0 affinity chromatography technology Hein MY (2015) 1
SEC16A 7 CLTA 1 affinity chromatography technology Hein MY (2015) 1
CLTC 12 STON2 2 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 KIF3A 4 affinity chromatography technology Emdal KB (2015) 1
DMWD 3 GAK 5 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
LIMA1 4 CLINT1 1 affinity chromatography technology Hein MY (2015) 1
SEC16A 7 PIK3C2A 7 affinity chromatography technology Hein MY (2015) 1
STAMBPL1 2 CLTCL1 4 affinity chromatography technology Huttlin EL (2017) 1
PICALM 0 CLTC 12 affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology Tebar F (1999), Tebar F (1999), Hein MY (2015), Hein MY (2015) 4
HSPA8 4 WNK1 7 affinity chromatography technology Huttlin EL (2017) 1
PICALM 0 CLINT1 1 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Huttlin EL (2017) 2
AP2A1 1 PICALM 0 biochemical, affinity chromatography technology Havugimana PC (2012), Huttlin EL (2017) 2
NTRK1 1 HSPBP1 0 affinity chromatography technology Emdal KB (2015) 1
GOLGB1 8 USO1 1 pull down Dirac-Svejstrup AB (2000) 1
TRIM25 5 PSMA5 0 affinity chromatography technology Choudhury NR (2017) 1
SEC16A 7 CPSF7 4 affinity chromatography technology Hein MY (2015) 1
LIMA1 4 AFAP1 3 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 AP2B1 3 affinity chromatography technology Hein MY (2015) 1
STAMBP 2 GAK 5 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
GTSE1 3 STAMBP 2 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Huttlin EL (2017) 2
LIMA1 4 CPM 2 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 HSPA8 4 affinity chromatography technology Emdal KB (2015) 1
NTRK1 1 AP2A1 1 affinity chromatography technology Emdal KB (2015) 1
GAK 5 CLTCL1 4 affinity chromatography technology Hein MY (2015) 1
ATP13A2 1 AAK1 4 two hybrid, affinity chromatography technology Usenovic M (2012), Usenovic M (2012) 2
PICALM 0 TRIM25 5 biochemical Wan C (2015) 1
NTRK1 1 PSMA5 0 affinity chromatography technology Emdal KB (2015) 1
PICALM 0 EPS15 1 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Huttlin EL (2017) 2
NTRK1 1 RABGEF1 1 affinity chromatography technology Emdal KB (2015) 1
GTSE1 3 RBM14 5 affinity chromatography technology Hein MY (2015) 1
PICALM 0 AP2B1 3 affinity chromatography technology Hein MY (2015) 1
AP2A1 1 AP2B1 3 biochemical Wan C (2015) 1
CLTB 0 MYO6 3 affinity chromatography technology Hein MY (2015) 1
PPM1B 2 SPTAN1 9 affinity chromatography technology St-Denis N (2016) 1
HSPBP1 0 EDRF1 6 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
NTRK1 1 CLTA 1 affinity chromatography technology Emdal KB (2015) 1
GTSE1 3 GAK 5 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
MYO6 3 CLTC 12 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Buss F (2001), Hein MY (2015), Wollscheid HP (2016) 3
NTRK1 1 MYO1C 5 affinity chromatography technology Emdal KB (2015) 1
GAK 5 SEC13 0 affinity chromatography technology Hein MY (2015) 1
CLTB 0 NUMB 1 affinity chromatography technology Hein MY (2015) 1
SEC16A 7 AP2A1 1 affinity chromatography technology Hein MY (2015) 1
IARS2 2 APP 1 pull down Olah J (2011) 1
CLTC 12 AP2B1 3 affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology Slepnev VI (2000), Knuehl C (2006), Knuehl C (2006), Hein MY (2015) 4
GAK 5 CLTA 1 affinity chromatography technology Hein MY (2015) 1
CCNG1 1 APP 1 pull down Olah J (2011) 1
CLTC 12 BMP2K 0 affinity chromatography technology Hein MY (2015) 1
STAMBP 2 CLTC 12 affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology Nakamura M (2006), Nakamura M (2006), McCullough J (2006), McCullough J (2006), McCullough J (2006), Hein MY (2015) 6
GAK 5 CCNG1 1 affinity chromatography technology, pull down Kanaoka Y (1997), Kanaoka Y (1997) 2
GAK 5 APP 1 pull down Olah J (2011) 1
DBN1 1 SEC16A 7 affinity chromatography technology Hein MY (2015) 1
PICALM 0 MYO6 3 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Wollscheid HP (2016) 2
CLTC 12 DENND1A 2 affinity chromatography technology Hein MY (2015) 1
HSPBP1 0 APP 1 pull down Olah J (2011) 1
PSMA5 0 APP 1 pull down Olah J (2011) 1
STAMBP 2 CHMP4A 1 two hybrid, two hybrid Row PE (2007), Tsang HT (2006) 2
TNK2 7 ALK 8 affinity chromatography technology Pao-Chun L (2009) 1
GTSE1 3 LIMA1 4 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 CDK5 0 affinity chromatography technology Emdal KB (2015) 1
LIMA1 4 SYNPO 5 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
CLINT1 1 BMP2K 0 affinity chromatography technology Huttlin EL (2017) 1
GAK 5 TNK2 7 affinity chromatography technology Hein MY (2015) 1
HSPA8 4 CAPZB 2 affinity chromatography technology, pull down, fluorescent resonance energy transfe Hishiya A (2010), Hishiya A (2010), Hishiya A (2010) 3
DAB2 1 AP2M1 5 affinity chromatography technology Mulkearns EE (2012) 1
SYNPO 5 CLTC 12 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 PICALM 0 affinity chromatography technology Emdal KB (2015) 1
LGR4 3 PIK3C2A 7 affinity chromatography technology Carmon KS (2014) 1
MYO1C 5 SPTAN1 9 affinity chromatography technology Hein MY (2015) 1
CLTA 1 CLTCL1 4 biochemical Wan C (2015) 1
HSPA8 4 GAK 5 affinity chromatography technology Huttlin EL (2017) 1
HIP1 4 CLTB 0 pull down, pull down, pull down, x-ray crystallography Legendre-Guillemin V (2005), Legendre-Guillemin V (2005), Wilbur JD (2008), Wilbur JD (2008) 4
ATP13A2 1 GAK 5 two hybrid, affinity chromatography technology Usenovic M (2012), Usenovic M (2012) 2
CLTB 0 CLTA 1 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Boldt K (2016) 2
STAMBPL1 2 NUMB 1 affinity chromatography technology Huttlin EL (2017) 1
STAMBPL1 2 BMP2K 0 affinity chromatography technology Huttlin EL (2017) 1
CLTC 12 EPS15 1 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Chi S (2008) 2
STAMBP 2 AP2A1 1 affinity chromatography technology Huttlin EL (2017) 1
GTSE1 3 WNK1 7 affinity chromatography technology Hein MY (2015) 1
TRIM25 5 PIK3C2A 7 affinity chromatography technology Choudhury NR (2017) 1
DBN1 1 CLTC 12 affinity chromatography technology Hein MY (2015) 1
SP1 0 CAPZB 2 affinity chromatography technology Chuang JY (2012) 1
RABGEF1 1 GAK 5 affinity chromatography technology Huttlin EL (2017) 1
CLTC 12 PIK3C2A 7 affinity chromatography technology Hein MY (2015) 1
TRIM25 5 WNK1 7 affinity chromatography technology Choudhury NR (2017) 1
GAK 5 PIK3C2A 7 affinity chromatography technology Hein MY (2015) 1
HSPA8 4 EDRF1 6 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Taipale M (2014), Taipale M (2014), Huttlin EL (2017) 3
TRIM25 5 AP2B1 3 affinity chromatography technology Choudhury NR (2017) 1
GAK 5 AP2M1 5 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 TNK2 7 affinity chromatography technology Hein MY (2015) 1
CLTC 12 USO1 1 affinity chromatography technology Hein MY (2015) 1
TRIM25 5 CCNG1 1 affinity chromatography technology Choudhury NR (2017) 1
CLINT1 1 PIK3C2A 7 affinity chromatography technology Huttlin EL (2017) 1
AAK1 4 AP2A1 1 affinity chromatography technology So J (2015) 1
TRIM25 5 XPR1 3 affinity chromatography technology Choudhury NR (2017) 1
PICALM 0 CLTB 0 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
GAK 5 RBM14 5 affinity chromatography technology Hein MY (2015) 1
SEC16A 7 CLTB 0 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
TRIM25 5 HIP1 4 affinity chromatography technology Choudhury NR (2017) 1
GAK 5 FEM1B 1 affinity chromatography technology Hein MY (2015) 1
PICALM 0 DENND1A 2 affinity chromatography technology Hein MY (2015) 1
GAK 5 FAM83H 6 affinity chromatography technology Hein MY (2015) 1
EPS15 1 HSPA8 4 affinity chromatography technology Brehme M (2009) 1
AP2M1 5 AAK1 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Brehme M (2009), Li J (2013), So J (2015), Huttlin EL (2015), Huttlin EL (2017) 5
PICALM 0 CLTCL1 4 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Huttlin EL (2017) 2
SEC16A 7 SEC24C 2 affinity chromatography technology Hein MY (2015) 1
CLTB 0 WNK1 7 affinity chromatography technology Hein MY (2015) 1
GAK 5 CLTC 12 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
GAK 5 PPM1B 2 biochemical Wan C (2015) 1
MYO6 3 AP2M1 5 affinity chromatography technology Wollscheid HP (2016) 1
DBN1 1 CAPZB 2 affinity chromatography technology Hein MY (2015) 1
CLTC 12 SEC13 0 affinity chromatography technology Hein MY (2015) 1
DBN1 1 CEP162 3 affinity chromatography technology Hein MY (2015) 1
CLTB 0 DENND1A 2 affinity chromatography technology Hein MY (2015) 1
CLINT1 1 CLTC 12 pull down, pull down, affinity chromatography technology Kalthoff C (2002), Mills IG (2003), Hein MY (2015) 3
AAK1 4 WNK1 7 affinity chromatography technology Boldt K (2016) 1
DBN1 1 GTSE1 3 affinity chromatography technology Hein MY (2015) 1
STAMBP 2 CLTCL1 4 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
MYO1C 5 INF2 5 affinity chromatography technology Hein MY (2015) 1
NUMB 1 EPS15 1 affinity chromatography technology Confalonieri S (2000) 1
SYNPO 5 CAPZB 2 affinity chromatography technology Hein MY (2015) 1
GAK 5 PHGDH 4 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 PHGDH 4 affinity chromatography technology Emdal KB (2015) 1
TRIM25 5 FAM83B 0 affinity chromatography technology Choudhury NR (2017) 1
GTSE1 3 HIP1R 5 affinity chromatography technology Hein MY (2015) 1
GAK 5 KIF3A 4 affinity chromatography technology Hein MY (2015) 1
SEC16A 7 BMP2K 0 affinity chromatography technology Hein MY (2015) 1
SEC16A 7 CLINT1 1 affinity chromatography technology Hein MY (2015) 1
CLINT1 1 STON2 2 affinity chromatography technology Huttlin EL (2017) 1
GTSE1 3 ZNF106 2 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 NUMB 1 affinity chromatography technology Hein MY (2015) 1
HIP1 4 HIP1R 5 affinity chromatography technology, pull down, affinity chromatography technology Legendre-Guillemin V (2002), Legendre-Guillemin V (2002), Huttlin EL (2017) 3
CBLC 1 GAK 5 affinity chromatography technology Huttlin EL (2017) 1
DBN1 1 PIK3C2A 7 affinity chromatography technology Hein MY (2015) 1
TRIM25 5 HIP1R 5 affinity chromatography technology Choudhury NR (2017) 1
GTSE1 3 USO1 1 affinity chromatography technology Hein MY (2015) 1
MYO6 3 CLINT1 1 affinity chromatography technology Wollscheid HP (2016) 1
CLTB 0 AP2A2 3 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 STAMBPL1 2 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Huttlin EL (2017) 2
SYNPO 5 CLTB 0 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 SEC24C 2 affinity chromatography technology Hein MY (2015) 1
CLTB 0 HIP1R 5 affinity chromatography technology, pull down Hein MY (2015), Legendre-Guillemin V (2005) 2
STAMBP 2 CLTA 1 affinity chromatography technology Sowa ME (2009) 1
NTRK1 1 AAK1 4 affinity chromatography technology Emdal KB (2015) 1
TRIM25 5 FEM1B 1 affinity chromatography technology Choudhury NR (2017) 1
CLTC 12 CPSF7 4 affinity chromatography technology Hein MY (2015) 1
PICALM 0 SEC24C 2 biochemical Havugimana PC (2012) 1
MYO6 3 SEC16A 7 affinity chromatography technology Wollscheid HP (2016) 1
GAK 5 DENND1A 2 affinity chromatography technology Hein MY (2015) 1
CLTC 12 TNK1 0 affinity chromatography technology Hein MY (2015) 1
DBN1 1 CALM1 0 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 SEC16A 7 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
PICALM 0 SEC13 0 affinity chromatography technology Hein MY (2015) 1
TRIM25 5 GAK 5 affinity chromatography technology Choudhury NR (2017) 1
TRIM25 5 PHGDH 4 affinity chromatography technology Choudhury NR (2017) 1
LIMA1 4 BMP2K 0 affinity chromatography technology Hein MY (2015) 1
MYO6 3 AP2B1 3 affinity chromatography technology Wollscheid HP (2016) 1
TNK2 7 CLTC 12 pull down, pull down, affinity chromatography technology, affinity chromatography technology Teo M (2001), Liu NS (2009), Hein MY (2015), Mahendrarajah N (2017) 4
USO1 1 SEC16A 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology van Zuylen WJ (2012), van Zuylen WJ (2012), Hein MY (2015) 3
GTSE1 3 CLINT1 1 affinity chromatography technology Hein MY (2015) 1
AP2M1 5 CLTC 12 affinity chromatography technology, affinity chromatography technology Brehme M (2009), Hein MY (2015) 2
LIMA1 4 HIP1R 5 affinity chromatography technology Hein MY (2015) 1
LIMA1 4 AP2A2 3 affinity chromatography technology Hein MY (2015) 1
DAB2 1 AXIN1 1 pull down Hocevar BA (2003) 1
XPR1 3 KIDINS220 4 affinity chromatography technology Huttlin EL (2017) 1
AP2A2 3 APP 1 pull down Olah J (2011) 1
GAK 5 CALML3 0 affinity chromatography technology Hein MY (2015) 1
HSPA8 4 SEC24C 2 biochemical, affinity chromatography technology, affinity chromatography technology Havugimana PC (2012), Taipale M (2014), Taipale M (2014) 3
GAK 5 DBN1 1 affinity chromatography technology Hein MY (2015) 1
SEC16A 7 GAK 5 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
STAMBPL1 2 PIK3C2A 7 affinity chromatography technology Huttlin EL (2017) 1
DBN1 1 AP2A2 3 affinity chromatography technology Hein MY (2015) 1
STON2 2 AP2M1 5 pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Walther K (2001), Brehme M (2009), Huttlin EL (2015), Huttlin EL (2017) 4
RABGEF1 1 CLINT1 1 affinity chromatography technology Huttlin EL (2017) 1
LIMA1 4 STON2 2 affinity chromatography technology Hein MY (2015) 1
PICALM 0 WNK1 7 affinity chromatography technology Hein MY (2015) 1
AP2M1 5 NUMB 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Li J (2013), Huttlin EL (2015), Huttlin EL (2017) 3
PICALM 0 SEC16A 7 affinity chromatography technology Hein MY (2015) 1
CLTB 0 BMP2K 0 affinity chromatography technology Hein MY (2015) 1
GAK 5 BMP2K 0 affinity chromatography technology Hein MY (2015) 1
MYO1C 5 AFAP1 3 affinity chromatography technology Hein MY (2015) 1
DAB2 1 AP2A1 1 affinity chromatography technology Mulkearns EE (2012) 1
SEC16A 7 FAM83B 0 affinity chromatography technology Hein MY (2015) 1
FBXW7 2 AP2A1 1 genetic interference Bailey ML (2015) 1
NTRK1 1 CAPZB 2 affinity chromatography technology Emdal KB (2015) 1
NTRK1 1 USO1 1 affinity chromatography technology Emdal KB (2015) 1
SYNPO 5 AP2M1 5 affinity chromatography technology Hein MY (2015) 1
FBXW7 2 GAK 5 genetic interference Bailey ML (2015) 1
MPP5 2 GAK 5 affinity chromatography technology Huttlin EL (2017) 1
LIMA1 4 DAB2 1 affinity chromatography technology Hein MY (2015) 1
SYNPO 5 INF2 5 affinity chromatography technology Hein MY (2015) 1
SP1 0 DBN1 1 affinity chromatography technology Chuang JY (2012) 1
PUS7L 0 APP 1 pull down Olah J (2011) 1
LIMA1 4 MISP 4 affinity chromatography technology Hein MY (2015) 1
SYNPO 5 CLTA 1 affinity chromatography technology Hein MY (2015) 1
STAMBPL1 2 CLINT1 1 affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Huttlin EL (2017) 2
NTRK1 1 MYO6 3 affinity chromatography technology Emdal KB (2015) 1
STAMBPL1 2 HIP1R 5 affinity chromatography technology Huttlin EL (2017) 1
STAMBPL1 2 WNK1 7 affinity chromatography technology Huttlin EL (2017) 1
LIMA1 4 DBN1 1 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
PICALM 0 CLTA 1 affinity chromatography technology Hein MY (2015) 1
TRIM25 5 SYNPO 5 affinity chromatography technology Choudhury NR (2017) 1
TRIM25 5 AP2M1 5 affinity chromatography technology Choudhury NR (2017) 1
DBN1 1 CLTCL1 4 affinity chromatography technology Hein MY (2015) 1
GAK 5 CPM 2 affinity chromatography technology Hein MY (2015) 1
EPS15 1 AP2A2 3 pull down, affinity chromatography technology, affinity chromatography technology, pull down Bean AJ (2000), Roxrud I (2008), Brehme M (2009), Shimada A (2016) 4
CLTB 0 AAK1 4 affinity chromatography technology Hein MY (2015) 1
CLTC 12 NUMB 1 affinity chromatography technology Hein MY (2015) 1
SYNPO 5 BMP2K 0 affinity chromatography technology Hein MY (2015) 1
GAK 5 AP2B1 3 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 XPR1 3 affinity chromatography technology Emdal KB (2015) 1
SYNPO 5 PIK3C2A 7 affinity chromatography technology Hein MY (2015) 1
EPS15 1 AP2A1 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology van Delft S (1997), Kariya K (2000), Confalonieri S (2000), Brehme M (2009) 4
GTSE1 3 EPS15 1 affinity chromatography technology Hein MY (2015) 1
CLINT1 1 AP2A1 1 pull down, affinity chromatography technology Kalthoff C (2002), Huttlin EL (2017) 2
AP2B1 3 SEC24C 2 biochemical Kristensen AR (2012) 1
NTRK1 1 RBM14 5 affinity chromatography technology Emdal KB (2015) 1
TRIM25 5 AFAP1 3 affinity chromatography technology Choudhury NR (2017) 1
TRIM25 5 CLTA 1 affinity chromatography technology Choudhury NR (2017) 1
GAK 5 HIP1R 5 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Huttlin EL (2017) 2
LIMA1 4 INF2 5 affinity chromatography technology Hein MY (2015) 1
CLINT1 1 AP2B1 3 pull down, biochemical Kalthoff C (2002), Wan C (2015) 2
PICALM 0 AP2M1 5 affinity chromatography technology Hein MY (2015) 1
GAK 5 XPR1 3 affinity chromatography technology Hein MY (2015) 1
PHGDH 4 APP 1 pull down Olah J (2011) 1
CLTB 0 AP2M1 5 affinity chromatography technology Hein MY (2015) 1
STAMBP 2 BMP2K 0 affinity chromatography technology Huttlin EL (2017) 1
DBN1 1 CLTA 1 affinity chromatography technology Hein MY (2015) 1
HIP1R 5 PICALM 0 biochemical, biochemical, affinity chromatography technology Havugimana PC (2012), Wan C (2015), Hein MY (2015) 3
DBN1 1 CPM 2 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 HIP1 4 affinity chromatography technology Hein MY (2015) 1
AP2A2 3 DAB2 1 affinity chromatography technology, affinity chromatography technology Morris SM (2001), Mulkearns EE (2012) 2
PICALM 0 GAK 5 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
GAK 5 EDRF1 6 affinity chromatography technology Hein MY (2015) 1
GAK 5 ZNF106 2 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 MYO6 3 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 CLINT1 1 affinity chromatography technology Emdal KB (2015) 1
SYNPO 5 DBN1 1 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
SP1 0 CALM1 0 affinity chromatography technology Chuang JY (2012) 1
WNK1 7 ZNF106 2 two hybrid Bandyopadhyay S (2010) 1
GAK 5 GOLGB1 8 affinity chromatography technology Hein MY (2015) 1
HSPBP1 0 GAK 5 affinity chromatography technology Huttlin EL (2017) 1
PICALM 0 DAB2 1 affinity chromatography technology Hein MY (2015) 1
NTRK1 1 SEC16A 7 affinity chromatography technology Emdal KB (2015) 1
SYNPO 5 MYO6 3 affinity chromatography technology Hein MY (2015) 1
DBN1 1 INF2 5 affinity chromatography technology Hein MY (2015) 1
AP2M1 5 CLINT1 1 affinity chromatography technology, affinity chromatography technology Brehme M (2009), Huttlin EL (2017) 2
GAK 5 MYO6 3 affinity chromatography technology Hein MY (2015) 1
DAB2 1 APP 1 pull down Morris SM (2001) 1
LGR4 3 KIDINS220 4 affinity chromatography technology Carmon KS (2014) 1
NTRK1 1 AP2B1 3 affinity chromatography technology Emdal KB (2015) 1
GAK 5 SEC24C 2 affinity chromatography technology Hein MY (2015) 1
WNK1 7 CLTC 12 two hybrid, affinity chromatography technology Bandyopadhyay S (2010), Hein MY (2015) 2
NTRK1 1 CPSF7 4 affinity chromatography technology Emdal KB (2015) 1
LIMA1 4 SEC16A 7 affinity chromatography technology Hein MY (2015) 1
GAK 5 PARP10 4 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 KIDINS220 4 affinity chromatography technology Hein MY (2015) 1
DAB2 1 CLTC 12 affinity chromatography technology, affinity chromatography technology Mulkearns EE (2012), Hein MY (2015) 2
NUMB 1 AP2A1 1 affinity chromatography technology, pull down Nishimura T (2003), Nishimura T (2003) 2
DBN1 1 EPS15 1 affinity chromatography technology Hein MY (2015) 1
CLASRP 1 APP 1 pull down Olah J (2011) 1
AP2A2 3 AP2B1 3 biochemical Wan C (2015) 1
NTRK1 1 GAK 5 affinity chromatography technology Emdal KB (2015) 1
SEC16A 7 CLTC 12 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
AAK1 4 APP 1 pull down Olah J (2011) 1
GAK 5 CHMP4A 1 affinity chromatography technology Hein MY (2015) 1
GAK 5 FAM83B 0 affinity chromatography technology Hein MY (2015) 1
CLTC 12 AP2A1 1 affinity chromatography technology Hein MY (2015) 1
GTSE1 3 CLTCL1 4 affinity chromatography technology Hein MY (2015) 1
SYNPO 5 STON2 2 affinity chromatography technology Hein MY (2015) 1
AAK1 4 AP2B1 3 affinity chromatography technology So J (2015) 1
TRIM25 5 FAM83H 6 affinity chromatography technology Choudhury NR (2017) 1
CLTA 1 HSPA8 4 unspecified method DeLuca-Flaherty C (1990) 1