Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
NALCN 259232 PYRIMETHAMINE CHEMBL36 channel blocker GuideToPharmacologyInteractions
NALCN 259232 COBALT (II) ION CHEMBL59093 channel blocker GuideToPharmacologyInteractions
NALCN 259232 VERAPAMIL CHEMBL6966 channel blocker GuideToPharmacologyInteractions

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
NALCN rs9585618 C ziprasidone efficacy yes as measured by changes in PANSS-T (positive and negative syndrome scale total score), using a mixed model repeated measures approach. Examined 6789 SNPs - p-value of p< or equal to 5x10-4 was considered significant. It was unclear whether the allele was associated with an increased or decreased response to drug. Allele C is associated with response to ziprasidone in people with Schizophrenia. 22920393 981238803