PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
C10orf76	0	PTPN23	7	genetic interference	Blomen VA (2015)	1
KLC1	5	KLC2	2	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	5
TUBG1	2	CAD	10	affinity chromatography technology	Fogeron ML (2013)	1
ITGA4	4	VCP	6	affinity chromatography technology	Byron A (2012)	1
VPS26A	0	P3H1	2	affinity chromatography technology	Hein MY (2015)	1
PTPN23	7	STIP1	1	affinity chromatography technology	Yadav L (2017)	1
NTRK1	1	UBC	7	affinity chromatography technology	Emdal KB (2015)	1
CLTA	1	CLTC	12	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
FGL1	3	PTPN23	7	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NTRK1	1	KLC1	5	affinity chromatography technology	Emdal KB (2015)	1
RPN1	2	UBC	7	pull down	Shi Y (2016)	1
PTPN23	7	VPS26A	0	biochemical	Havugimana PC (2012)	1
EGFR	5	STIP1	1	protein complementation assay	Deribe YL (2009)	1
ITGA4	4	CLTC	12	affinity chromatography technology	Byron A (2012)	1
TUBG1	2	STIP1	1	affinity chromatography technology	Hein MY (2015)	1
KIF20A	3	PTPN23	7	affinity chromatography technology	Hein MY (2015)	1
NTRK1	1	SHMT2	3	affinity chromatography technology	Emdal KB (2015)	1
VCP	6	STIP1	1	biochemical	Wan C (2015)	1
NTRK1	1	HSPH1	0	affinity chromatography technology	Emdal KB (2015)	1
PSMA3	1	CALR	1	affinity chromatography technology	Fedorova OA (2011)	1
LRRK2	5	PTPN23	7	two hybrid	Zheng XY (2008)	1
KIF5B	1	PPP4R3B	3	biochemical	Kristensen AR (2012)	1
UBC	7	VCP	6	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down	Matsumoto M (2005), Zhong X (2006), Dai RM (2001), Bish RA (2007), Lim JJ (2016), Zhang X (2017)	6
HGS	5	STAM2	0	two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Rual JF (2005), Bache KG (2003), Bache KG (2003), Mizuno E (2004), Kanazawa C (2003), Kanazawa C (2003), Stuible M (2010), Havugimana PC (2012), Hoeller D (2006), Wan C (2015)	10
NTRK1	1	CLTC	12	affinity chromatography technology	Emdal KB (2015)	1
ITGA4	4	NTPCR	2	affinity chromatography technology	Byron A (2012)	1
SHMT2	3	HGS	5	affinity chromatography technology	Castello A (2012)	1
PTPN23	7	SH3GL2	1	two hybrid, affinity chromatography technology	Ichioka F (2007), Ichioka F (2007)	2
GRB2	2	VCP	6	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
UBC	7	UBAP1	2	pull down, pull down, pull down, pull down	Fenner BJ (2009), Stefani F (2011), Kharitidi D (2015), Zhang X (2017)	4
STAM2	0	USP8	7	unspecified method, pull down, affinity chromatography technology, pull down, protein complementation assay	Kaneko T (2003), Kato M (2000), Kato M (2000), Kato M (2000), Berlin I (2010)	5
NTRK1	1	CAD	10	affinity chromatography technology	Emdal KB (2015)	1
TRIM27	2	PTPN23	7	two hybrid	Rolland T (2014)	1
CLTB	0	CLINT1	1	affinity chromatography technology	Hein MY (2015)	1
PTPN23	7	TSG101	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Ichioka F (2007), Ichioka F (2007), Kharitidi D (2015)	3
ITGA4	4	CLTA	1	affinity chromatography technology	Byron A (2012)	1
EGFR	5	HSPA4	3	protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Deribe YL (2009), Deribe YL (2009), Citri A (2002), Tong J (2008), Kotlyar M (2015), Petschnigg J (2014)	6
VCP	6	PTPN23	7	affinity chromatography technology	Yu CC (2013)	1
HSPA4	3	HSPH1	0	biochemical, biochemical	Kristensen AR (2012), Wan C (2015)	2
PDCD6IP	3	CHMP4B	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ichioka F (2007), Ichioka F (2007), von Schwedler UK (2003), Zhou X (2010), Sette P (2013), Hein MY (2015), Dores MR (2015)	7
TRIM27	2	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
NTRK1	1	CALR	1	affinity chromatography technology	Emdal KB (2015)	1
VCP	6	CEP55	2	affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Fogeron ML (2013)	2
NTRK1	1	KLC2	2	affinity chromatography technology	Emdal KB (2015)	1
KIF5B	1	KLC1	5	pull down, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Diefenbach RJ (2002), Rahman A (1998), Rahman A (1999), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	9
USP8	7	GRB2	2	pull down	Kato M (2000)	1
EGFR	5	USP8	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Mizuno E (2005), Meijer IM (2013), Meijer IM (2013), Ali N (2013), Reincke M (2015), Reincke M (2015), Jeong CH (2015)	7
CLTC	12	HGS	5	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Raiborg C (2001), Raiborg C (2001), Nakamura M (2006), Zlatic SA (2011)	4
PTPN23	7	USP8	7	affinity chromatography technology	Ali N (2013)	1
PTPN23	7	CHMP4B	2	two hybrid, affinity chromatography technology	Ichioka F (2007), Ichioka F (2007)	2
USP8	7	UBC	7	enzymatic study, unspecified method, enzymatic study, x-ray crystallography, enzymatic study, enzymatic study, pull down	Faesen AC (2011), Ernst A (2013), Row PE (2007), Ernst A (2013), Wauer T (2015), Reincke M (2015), Kwasna D (2018)	7
PRDX5	0	PTPN23	7	biochemical	Havugimana PC (2012)	1
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
LGR4	3	PTPN23	7	affinity chromatography technology	Carmon KS (2014)	1
LRRK2	5	SH3GL2	1	enzymatic study	Matta S (2012)	1
KLC1	5	PTPN23	7	biochemical	Kristensen AR (2012)	1
PDCD6IP	3	CEP55	2	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, two hybrid	Morita E (2007), Morita E (2007), Morita E (2007), Carlton JG (2007), Carlton JG (2007), Lee HH (2008), Lee HH (2008), Lee HH (2008), Suzuki H (2008), Rolland T (2014)	10
NTRK1	1	KIF5B	1	affinity chromatography technology	Emdal KB (2015)	1
LRRK2	5	CLTC	12	affinity chromatography technology	Daechsel JC (2007)	1
PTPN23	7	STAM	3	affinity chromatography technology	Kharitidi D (2015)	1
PDCD6IP	3	ALG2	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Ichioka F (2007), Ichioka F (2007), Okumura M (2009), Okumura M (2009), Katoh K (2005), Katoh K (2005), Inuzuka T (2010), Shibata H (2008)	8
PTPN23	7	TUBB4A	3	affinity chromatography technology	Yadav L (2017)	1
TUBG1	2	HSPA4	3	biochemical	Wigley WC (1999)	1
ITGA4	4	GRB2	2	affinity chromatography technology	Byron A (2012)	1
PDCD6IP	3	TSG101	1	two hybrid, two hybrid, affinity chromatography technology, two hybrid, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid	Kim BY (2007), Ichioka F (2007), Ichioka F (2007), von Schwedler UK (2003), Schlundt A (2009), Schlundt A (2009), Schlundt A (2009), Okumura M (2009), Katoh K (2005), Strack B (2003), Strack B (2003), Zhou X (2010), Zhou X (2010), Carlton JG (2008)	14
NTRK1	1	TUBG1	2	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	HGS	5	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	PTPN23	7	affinity chromatography technology	Emdal KB (2015)	1
HSPA4	3	VCP	6	affinity chromatography technology, affinity chromatography technology	Vij N (2006), Yu CC (2013)	2
PTPN23	7	UBAP1	2	two hybrid, affinity chromatography technology, pull down, two hybrid, x-ray crystallography, unspecified method	Stefani F (2011), Kharitidi D (2015), Gahloth D (2016), Gahloth D (2016), Gahloth D (2016), Gahloth D (2016)	6
DIAPH1	4	PTPN23	7	biochemical	Kristensen AR (2012)	1
NTRK1	1	PSMA3	1	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	RPN1	2	affinity chromatography technology	Emdal KB (2015)	1
LGR4	3	UBC	7	affinity chromatography technology	Carmon KS (2014)	1
PTPN23	7	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
VCP	6	RPN1	2	affinity chromatography technology	Yu CC (2013)	1
KIF20A	3	VCP	6	affinity chromatography technology	Hein MY (2015)	1
HSPH1	0	STIP1	1	biochemical	Wan C (2015)	1
NTRK1	1	VPS26A	0	affinity chromatography technology	Emdal KB (2015)	1
GRB2	2	PDCD6IP	3	two hybrid, two hybrid	Bandyopadhyay S (2010), Wang J (2011)	2
KLC2	2	PPP4R3B	3	biochemical	Kristensen AR (2012)	1
PTPN23	7	HGS	5	affinity chromatography technology, affinity chromatography technology	Ali N (2013), Kharitidi D (2015)	2
CLTC	12	CLTB	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015), Zlatic SA (2011)	3
AURKA	1	CEP55	2	affinity chromatography technology	Fogeron ML (2013)	1
GRAP2	0	PTPN23	7	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PTPN23	7	CLTB	0	affinity chromatography technology	St-Denis N (2016)	1
PTPN23	7	SHMT2	3	affinity chromatography technology	Yadav L (2017)	1
TSG101	1	CEP55	2	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, two hybrid	Rual JF (2005), Morita E (2007), Morita E (2007), Morita E (2007), Morita E (2007), Carlton JG (2007), Carlton JG (2007), Lee HH (2008), Rolland T (2014)	9
NTRK1	1	P3H1	2	affinity chromatography technology	Emdal KB (2015)	1
CLTC	12	PTPN23	7	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), St-Denis N (2016)	2
DIAPH1	4	KIF5B	1	biochemical	Kristensen AR (2012)	1
LGR4	3	CALR	1	affinity chromatography technology	Carmon KS (2014)	1
LGR4	3	CLTC	12	affinity chromatography technology	Carmon KS (2014)	1
GRAP2	0	USP8	7	pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Berry DM (2002), Berry DM (2002), Huttlin EL (2015), Dufner A (2015), Huttlin EL (2017)	5
CLTA	1	VCP	6	affinity chromatography technology	Pleasure IT (1993)	1
KIF5B	1	PTPN23	7	biochemical	Kristensen AR (2012)	1
NTRK1	1	PDCD6IP	3	affinity chromatography technology	Emdal KB (2015)	1
GRB2	2	UBC	7	two hybrid	Bandyopadhyay S (2010)	1
UBC	7	PSMA3	1	affinity chromatography technology	Matsumoto M (2005)	1
STAM	3	UBC	7	pull down, affinity chromatography technology, x-ray crystallography, pull down, pull down, pull down, unspecified method, pull down, pull down, x-ray crystallography, pull down	Kim MS (2006), Mizuno E (2006), Hong YH (2009), Nathan JA (2013), Nathan JA (2013), Stuible M (2010), Lim J (2011), Baiady N (2016), Kharitidi D (2015), Sundd M (2012), Zhang X (2017)	11
CLTC	12	HSPA4	3	affinity chromatography technology	Hein MY (2015)	1
PTPN23	7	PPP4R3B	3	biochemical	Kristensen AR (2012)	1
VCP	6	CALR	1	biochemical	Wan C (2015)	1
ITGA4	4	CHMP4B	2	affinity chromatography technology	Byron A (2012)	1
GRB2	2	DIAPH1	4	affinity chromatography technology	Bisson N (2011)	1
EGFR	5	STAM2	0	affinity chromatography technology, pull down	Kong C (2007), Morino C (2004)	2
LAGE3	0	PTPN23	7	biochemical	Havugimana PC (2012)	1
GRB2	2	PTPN23	7	two hybrid, biochemical, affinity chromatography technology	Bandyopadhyay S (2010), Wan C (2015), Huttlin EL (2017)	3
DIAPH1	4	PPP4R3B	3	biochemical	Kristensen AR (2012)	1
NTRK1	1	DIAPH1	4	affinity chromatography technology	Emdal KB (2015)	1
GRB2	2	TSG101	1	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Bisson N (2011)	2
PDCD6IP	3	PTPN23	7	affinity chromatography technology, affinity chromatography technology	Ichioka F (2007), Ichioka F (2007)	2
NME2	0	PRDX5	0	biochemical	Wan C (2015)	1
STAM	3	STAM2	0	imaging technique	Kanazawa C (2003)	1
SHMT2	3	C10orf76	0	affinity chromatography technology	Castello A (2012)	1
NTRK1	1	CLTA	1	affinity chromatography technology	Emdal KB (2015)	1
ITGA4	4	PTPN23	7	affinity chromatography technology	Byron A (2012)	1
EGFR	5	ARL1	0	affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Tong J (2014)	2
PSMA3	1	STIP1	1	affinity chromatography technology	Fedorova OA (2011)	1
EGFR	5	GRAP2	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
PTPN23	7	HSPA4	3	affinity chromatography technology	Yadav L (2017)	1
HGS	5	CEP55	2	two hybrid	Morita E (2007)	1
PTPN23	7	ARL1	0	affinity chromatography technology	Yadav L (2017)	1
PTPN23	7	CEP55	2	two hybrid	Rolland T (2014)	1
TSG101	1	HGS	5	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, unspecified method, unspecified method, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique	Rual JF (2005), Lu Q (2003), Lu Q (2003), Lu Q (2003), Kim BY (2007), Im YJ (2010), Schlundt A (2009), Schlundt A (2009), Pornillos O (2003), Pornillos O (2003), Bache KG (2003), Bache KG (2003), Bouamr F (2007), Kim HJ (2007), Kumar B (2016), Kumar B (2016)	16
EGFR	5	PSMA3	1	affinity chromatography technology	Yao Z (2017)	1
ITGA4	4	CAD	10	affinity chromatography technology	Byron A (2012)	1
CLTB	0	CLTA	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Boldt K (2016)	2
EGFR	5	SH3GL2	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schmidt MH (2004), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Liu W (2014), Liu W (2014)	6
PTPN23	7	P3H1	2	affinity chromatography technology	St-Denis N (2016)	1
ITGA4	4	PDCD6IP	3	affinity chromatography technology	Byron A (2012)	1
NME2	0	KIF5B	1	affinity chromatography technology	Ewing RM (2007)	1
NTRK1	1	EGFR	5	affinity chromatography technology	Emdal KB (2015)	1
CAD	10	CLTC	12	biochemical	Wan C (2015)	1
PTPN23	7	NTPCR	2	affinity chromatography technology	Yadav L (2017)	1
SHMT2	3	NOTCH2NL	1	affinity chromatography technology	Castello A (2012)	1
TSG101	1	UBAP1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Stefani F (2011), Stefani F (2011), Agromayor M (2012), Agromayor M (2012), Wunderley L (2014), Wunderley L (2014), Wunderley L (2014), Wan C (2015), Kharitidi D (2015), Huttlin EL (2017)	10
GRB2	2	TRIM27	2	two hybrid	Rolland T (2014)	1
C10orf76	0	UBAP1	2	genetic interference	Blomen VA (2015)	1
EGFR	5	TUBG1	2	affinity chromatography technology	Tong J (2014)	1
VCP	6	NME2	0	affinity chromatography technology	Yu CC (2013)	1
PTPN23	7	CAD	10	affinity chromatography technology	Yadav L (2017)	1
CLINT1	1	CLTC	12	pull down, pull down, affinity chromatography technology	Kalthoff C (2002), Mills IG (2003), Hein MY (2015)	3
LGR4	3	CAD	10	affinity chromatography technology	Carmon KS (2014)	1
PTPN23	7	CLTA	1	affinity chromatography technology	St-Denis N (2016)	1
NTRK1	1	STIP1	1	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	TSG101	1	affinity chromatography technology	Yao Z (2017)	1
PTPN23	7	RPN1	2	affinity chromatography technology	Yadav L (2017)	1
VCP	6	TSG101	1	affinity chromatography technology	Yu CC (2013)	1
LGR4	3	RPN1	2	affinity chromatography technology	Carmon KS (2014)	1
NTRK1	1	TSG101	1	affinity chromatography technology	Emdal KB (2015)	1
STAM	3	HGS	5	two hybrid, affinity chromatography technology, biochemical, pull down, imaging technique, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Asao H (1997), Bache KG (2003), Malik R (2010), Kanazawa C (2003), Kanazawa C (2003), Havugimana PC (2012), Sirisaengtaksin N (2014), Sirisaengtaksin N (2014), Holleman J (2014), Holleman J (2014), Wan C (2015), Berlin I (2010), Huttlin EL (2017)	14
NME2	0	STIP1	1	affinity chromatography technology, biochemical	Ewing RM (2007), Wan C (2015)	2
PDCD6IP	3	SH3GL2	1	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Schmidt MH (2004), Schmidt MH (2004), Ichioka F (2007), Ichioka F (2007)	4
SHMT2	3	UBAP1	2	affinity chromatography technology	Castello A (2012)	1
C10orf76	0	USP8	7	genetic interference	Blomen VA (2015)	1
ALG2	2	TSG101	1	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Okumura M (2009), Katoh K (2005), Katoh K (2005), Inuzuka T (2010)	4
PSMA3	1	VCP	6	biochemical	Wan C (2015)	1
TUBG1	2	PDCD6IP	3	affinity chromatography technology	Schmidt MH (2003)	1
NTRK1	1	STAM	3	affinity chromatography technology	Emdal KB (2015)	1
TUBG1	2	PTPN23	7	affinity chromatography technology	Fogeron ML (2013)	1
VWA5A	2	PTPN23	7	affinity chromatography technology	Huttlin EL (2017)	1
UBC	7	CEP55	2	pull down	Zhang X (2017)	1
PTPN23	7	CLINT1	1	affinity chromatography technology	St-Denis N (2016)	1
CHMP4B	2	TSG101	1	affinity chromatography technology	Hein MY (2015)	1
KLC2	2	KIF5B	1	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Rahman A (1998), Rahman A (1999), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Hein MY (2015)	7
STAM2	0	UBC	7	x-ray crystallography, x-ray crystallography, pull down, pull down, pull down, pull down, pull down	Lange A (2010), Lange A (2012), Lange A (2012), Stuible M (2010), Baiady N (2016), Zhang X (2017), Hologne M (2016)	7
DIAPH1	4	KLC1	5	biochemical	Kristensen AR (2012)	1
KLC1	5	PPP4R3B	3	biochemical	Kristensen AR (2012)	1
UBC	7	PTPN23	7	pull down	Kharitidi D (2015)	1
EGFR	5	HGS	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Umebayashi K (2008), Morino C (2004), Meijer IM (2013), Sun Y (2013), Ali N (2013), Tan X (2015)	6
TSG101	1	UBC	7	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, pull down, x-ray crystallography, pull down, pull down	Schlundt A (2009), Sundquist WI (2004), Bishop N (2002), Bishop N (2002), Pornillos O (2002), Kharitidi D (2015), Zhang X (2017)	7
PTPN23	7	GLUD1	2	affinity chromatography technology	Yadav L (2017)	1
PTPN23	7	EGFR	5	affinity chromatography technology	Ali N (2013)	1
VCP	6	CHMP4B	2	affinity chromatography technology	Hein MY (2015)	1
STAM2	0	PTPN23	7	affinity chromatography technology, affinity chromatography technology	Ali N (2013), Ali N (2013)	2
NTRK1	1	VCP	6	affinity chromatography technology	Emdal KB (2015)	1
ITGA4	4	PSMA3	1	affinity chromatography technology	Byron A (2012)	1
HGS	5	UBC	7	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down	Mizuno E (2006), Raiborg C (2002), Raiborg C (2002), Nathan JA (2013), Nathan JA (2013), Bishop N (2002), Stuible M (2010), Oved S (2006), Hoeller D (2006), Kharitidi D (2015), Zhang X (2017)	11
TUBG1	2	RPN1	2	affinity chromatography technology	Hein MY (2015)	1
GRB2	2	CLTC	12	affinity chromatography technology	Brehme M (2009)	1
GRB2	2	CAD	10	affinity chromatography technology	Brehme M (2009)	1
STAM2	0	VCP	6	biochemical	Kristensen AR (2012)	1
EGFR	5	UBC	7	affinity chromatography technology, affinity chromatography technology	Tong J (2009), Bishop N (2002)	2
EGFR	5	NTPCR	2	affinity chromatography technology	Tong J (2014)	1
STAM2	0	TSG101	1	biochemical	Wan C (2015)	1
EGFR	5	P3H1	2	affinity chromatography technology	Yao Z (2017)	1
EGFR	5	TUBB4A	3	affinity chromatography technology	Foerster S (2013)	1
KLC2	2	PTPN23	7	biochemical	Kristensen AR (2012)	1
EGFR	5	RPN1	2	affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Tong J (2014)	2
EGFR	5	CLTA	1	affinity chromatography technology, affinity chromatography technology	Wu SL (2006), Wu SL (2006)	2
CLTC	12	STAM	3	affinity chromatography technology, pull down	Nakamura M (2006), McCullough J (2006)	2
STIP1	1	HSPA4	3	affinity chromatography technology, pull down, pull down, pull down, biochemical	Johnson BD (1998), Horibe T (2011), Brinker A (2002), Graumann K (2000), Wan C (2015)	5
PTPN23	7	AURKA	1	biochemical	Havugimana PC (2012)	1
GRB2	2	NTRK1	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Song C (2002), MacDonald JI (2000), Emdal KB (2015), Emdal KB (2015)	4
EGFR	5	PDCD6IP	3	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Schmidt MH (2004), Schmidt MH (2003), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
SHMT2	3	HSPA4	3	affinity chromatography technology	Castello A (2012)	1
PRDX5	0	STAM	3	biochemical	Havugimana PC (2012)	1
PTPN23	7	HSPH1	0	affinity chromatography technology	Yadav L (2017)	1
LRRK2	5	HSPA4	3	affinity chromatography technology	Sen S (2009)	1
NTRK1	1	PPP4R3B	3	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	CLINT1	1	affinity chromatography technology	Emdal KB (2015)	1
PTPN23	7	CALR	1	affinity chromatography technology	Yadav L (2017)	1
NTRK1	1	GLUD1	2	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	CALR	1	affinity chromatography technology	Tong J (2014)	1
TUBG1	2	AURKA	1	affinity chromatography technology, affinity chromatography technology	Molli PR (2010), Molli PR (2010)	2
ITGA4	4	UBC	7	affinity chromatography technology	Byron A (2012)	1
UBC	7	TRIM27	2	affinity chromatography technology	Matsumoto M (2005)	1
NTRK1	1	USP8	7	affinity chromatography technology	Emdal KB (2015)	1
PTPN23	7	NME2	0	affinity chromatography technology	Yadav L (2017)	1
CLTC	12	RPN1	2	biochemical	Wan C (2015)	1
UBC	7	PDCD6IP	3	pull down	Zhang X (2017)	1
PTPN23	7	ZFYVE16	6	affinity chromatography technology	St-Denis N (2016)	1
GRB2	2	HGS	5	affinity chromatography technology	Bisson N (2011)	1
ITGA4	4	STIP1	1	affinity chromatography technology	Byron A (2012)	1
USP8	7	STAM	3	pull down, affinity chromatography technology, protein complementation assay, affinity chromatography technology	Kato M (2000), Berlin I (2010), Berlin I (2010), Row PE (2006)	4
CLTC	12	CHMP4B	2	affinity chromatography technology	Hein MY (2015)	1
PTPN23	7	ALG2	2	two hybrid, affinity chromatography technology	Ichioka F (2007), Ichioka F (2007)	2
PSMA3	1	PTPN23	7	two hybrid	Rolland T (2014)	1
NTRK1	1	HSPA4	3	affinity chromatography technology, affinity chromatography technology	Rao R (2010), Emdal KB (2015)	2