PPI network (data source: BioGrid)

Symbol A GeneA coding DNM count Symbol B GeneB coding DNM count Interaction detection method Publication Evidence
FBXO7 1 CLIP3 4 enzymatic study Teixeira FR (2016) 1
CASP8 1 RIPK1 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Chaudhary PM (2000), Oshima S (2009), Bertrand MJ (2008), Knox PG (2011), Kim S (2010), Cheung HH (2009), Tenev T (2011), Tenev T (2011), Mahul-Mellier AL (2011), Legarda-Addison D (2009), Biton S (2011), Bellail AC (2012), Bellail AC (2012), Lee EW (2012), Rebe C (2007), Feoktistova M (2012), Puliyappadamba VT (2013), Wu P (2014), Wu P (2014), Feoktistova M (2011), Selmi T (2015), Yamaguchi N (2015), Moquin DM (2013), Ranjan K (2016), Zinngrebe J (2016), Nakazawa S (2016), Zheng M (2016) 27
TNFRSF1A 3 CYLD 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Moquin DM (2013), Nakazawa S (2016), Elliott PR (2016) 3
RIPK1 2 CYLD 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Wright A (2007), Nagabhushana A (2011), ODonnell MA (2012), Wu GR (2017) 4
RIPK1 2 CLIP3 4 affinity chromatography technology Fujikura D (2012) 1
CASP8 1 FADD 1 biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Gajate C (2005), Micheau O (2003), Srinivasula SM (1997), Srinivasula SM (1997), Henshall DC (2003), Boldin MP (1996), Oshima S (2009), Thomas LR (2002), Ikner A (2011), Tenev T (2011), Ramakrishnan P (2011), Mahul-Mellier AL (2011), Won M (2010), Ryu SW (2003), Sinha SK (2004), Biton S (2011), Fu K (2012), Fu K (2012), Gonzalvez F (2012), Lee EW (2012), Rebe C (2007), Feoktistova M (2012), Wang J (2011), Puliyappadamba VT (2013), Choi H (2011), Feoktistova M (2011), Selmi T (2015), Yamaguchi N (2015), Saitoh Y (2016), Moquin DM (2013), Ranjan K (2016), Nakazawa S (2016), Jeong M (2017), Jeong M (2017), Pescatore A (2016) 35
CLIP3 4 CYLD 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Fujikura D (2012), Ding Z (2015), Ding Z (2015) 3
CLIP3 4 TNFRSF1A 3 two hybrid, affinity chromatography technology Fujikura D (2012), Fujikura D (2012) 2
RIPK1 2 FADD 1 two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Chen D (2002), Young JA (2011), Tenev T (2011), Ramakrishnan P (2011), Legarda-Addison D (2009), ODonnell MA (2012), Vanlangenakker N (2011), Biton S (2011), Biton S (2011), Lee EW (2012), Puliyappadamba VT (2013), Wu P (2014), Huttlin EL (2015), Baratchian M (2016), Moquin DM (2013), Ranjan K (2016), Pescatore A (2016), Zheng M (2016) 18
CYLD 2 AKT1 1 enzymatic study, affinity chromatography technology Yang WL (2013), Yang WL (2013) 2
CASP8 1 TNFRSF1A 3 biochemical Gajate C (2005) 1
AKT1 1 AKT2 1 affinity chromatography technology Huttlin EL (2017) 1
CLIP3 4 AKT2 1 affinity chromatography technology, affinity chromatography technology, pull down Ding J (2009), Ding J (2009), Ding J (2009) 3
CLIP3 4 AKT1 1 affinity chromatography technology, affinity chromatography technology, pull down Ding J (2009), Ding J (2009), Ding J (2009) 3
CASP8 1 CLIP3 4 affinity chromatography technology Fujikura D (2012) 1
CLIP3 4 SPDYA 1 affinity chromatography technology, affinity chromatography technology Ding Z (2015), Ding Z (2015) 2
TNFRSF1A 3 AKT1 1 fluorescent resonance energy transfe Ivanov AA (2017) 1
FADD 1 CLIP3 4 affinity chromatography technology Fujikura D (2012) 1
FADD 1 TNFRSF1A 3 biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Gajate C (2005), Hsu H (1996), Kumar A (2001), Zheng L (2006) 4
RIPK1 2 TNFRSF1A 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Kim JW (2000), Duan H (1997), Hsu H (1996), Blankenship JW (2009), Newton K (2008), Varfolomeev E (2008), Fearns C (2006), Vince JE (2009), Dynek JN (2010), Kim S (2010), Cheung HH (2009), Tenev T (2011), Mahul-Mellier AL (2011), Won M (2010), Glowacka WK (2012), Fan YH (2011), Cusson-Hermance N (2005), ODonnell MA (2012), Zheng L (2006), Vince JE (2007), Mitsuhashi S (2008), Kim TW (2013), Wertz IE (2004), Liao W (2008), Wang YB (2015), Chang YL (2014), Zilberman-Rudenko J (2016), Zemirli N (2014), Moquin DM (2013), Nakazawa S (2016), Jeong M (2017), Huttlin EL (2017), Elliott PR (2016) 33
FBXO7 1 SPDYA 1 enzymatic study Teixeira FR (2016) 1
CLIP3 4 TNFRSF21 2 two hybrid Fujikura D (2012) 1