PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
RND1	0	PLEKHG5	5	affinity chromatography technology	Goh LL (2012)	1
RND1	0	PSMB5	3	affinity chromatography technology, biochemical, affinity chromatography technology	Zhang N (2010), Zhang N (2010), Zhang N (2010)	3
ZNF212	1	CREB3L2	0	two hybrid	Gao J (2008)	1
RND1	0	UBXN11	1	two hybrid, pull down, pull down, affinity chromatography technology, biochemical	Katoh H (2002), Katoh H (2002), Katoh H (2002), Katoh H (2002), Katoh H (2002)	5
RND1	0	PLXNB2	14	two hybrid	Oinuma I (2003)	1
PDE6D	0	RND1	0	two hybrid, two hybrid	Nancy V (2002), Hanzal-Bayer M (2002)	2
PLXNB1	12	RND1	0	pull down, affinity chromatography technology, affinity chromatography technology	Oinuma I (2003), Oinuma I (2003), Goh LL (2012)	3
RND1	0	RGS14	2	affinity chromatography technology	Goh LL (2012)	1
ARHGAP5	3	RND1	0	two hybrid, affinity chromatography technology, pull down	Wennerberg K (2003), Wennerberg K (2003), Wennerberg K (2003)	3
ZNF212	1	RND1	0	two hybrid	Gao J (2008)	1
RND1	0	ID3	0	two hybrid	Gao J (2008)	1
RND1	0	ARHGAP35	12	affinity chromatography technology	Goh LL (2012)	1
RND1	0	CREB3L2	0	two hybrid	Gao J (2008)	1
RND1	0	GRB7	1	two hybrid, pull down	Vayssiere B (2000), Vayssiere B (2000)	2