Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
KANSL1	rs2532292	T	corticosteroids	efficacy	no	The drugs were fluticasone furoate (82% of patients) and fluticasone propionate (18%). Response was assessed as change in FEV1 from baseline over 8 weeks (or 12 for HZA106837). The cohort was the meta-analysis of a combination of 7 randomized, double-blind, placebo-controlled, parallel-group, multi center studies conducted in 26 countries. They included FFA109684, FFA109685, FFA109687, FFA112059, HZA106827, HZA106829, and HZA106837.	Allele T is not associated with response to corticosteroids in people with Asthma as compared to allele A.	27523435	1448258435
KANSL1	rs1528072	A	corticosteroids	efficacy	no	The drugs were fluticasone furoate (82% of patients) and fluticasone propionate (18%). Response was assessed as change in FEV1 from baseline over 8 weeks (or 12 for HZA106837). The cohort was the meta-analysis of a combination of 7 randomized, double-blind, placebo-controlled, parallel-group, multi center studies conducted in 26 countries. They included FFA109684, FFA109685, FFA109687, FFA112059, HZA106827, HZA106829, and HZA106837.	Allele A is not associated with response to corticosteroids in people with Asthma as compared to allele C.	27523435	1448258426