Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
HTR3E 285242 PUMOSETRAG CHEMBL1643880 TdgClinicalTrial
HTR3E 285242 CHEMBL1188853 CHEMBL1188853 TdgClinicalTrial
HTR3E 285242 TEDATIOXETINE CHEMBL2104986 antagonist ChemblInteractions
HTR3E 285242 RG3487 CHEMBL3544952 antagonist ChemblInteractions
HTR3E 285242 GRANISETRON CHEMBL289469 TdgClinicalTrial
HTR3E 285242 DOLASETRON CHEMBL2368925 TdgClinicalTrial

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
HTR3E rs6443950 A opioids dosage no Variant had no significant association with opioid dose in either the development sample or the validation sample. Allele A is not associated with dose of opioids in people with Pain as compared to allele T. 21398039 1449714478
HTR3E rs7627615 A opioids dosage no Variant had no significant association with opioid dose in either the development sample or the validation sample. Allele A is not associated with dose of opioids in people with Pain as compared to allele G. 21398039 1449714485
HTR3E rs7432211 C opioids dosage no Variant was significantly associated with opioid dose in the development sample, but lost significance in the validation sample. Allele C is not associated with dose of opioids in people with Pain as compared to allele T. 21398039 1449714054
HTR3E rs4912522 C opioids dosage no Variant was significantly associated with opioid dose in the development sample, but lost significance in the validation sample. Allele C is not associated with dose of opioids in people with Pain as compared to allele G. 21398039 1449714076