PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
RELA	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TBK1	1	TRIM9	3	affinity chromatography technology, affinity chromatography technology	Qin Y (2016), Qin Y (2016)	2
HIF1AN	0	CDC37	0	affinity chromatography technology	Rodriguez J (2016)	1
USP2	0	EGFR	5	affinity chromatography technology	Kim J (2012)	1
TRAF1	0	RB1CC1	9	affinity chromatography technology	Huttlin EL (2017)	1
TRIM23	3	TRAIP	0	two hybrid	Woodsmith J (2012)	1
LATS2	1	SKP1	0	affinity chromatography technology	Couzens AL (2013)	1
SASS6	1	SQSTM1	0	bioid	Gupta GD (2015)	1
TRAF6	0	TAX1BP1	3	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid	Ling L (2000), Ling L (2000), Ling L (2000), Wang J (2011)	4
HNRNPL	3	AGO2	10	affinity chromatography technology	Fei T (2017)	1
CNTROB	6	PLK1	0	bioid	Gupta GD (2015)	1
IRF3	4	AKT1	1	affinity chromatography technology	Joung SM (2011)	1
EGLN3	0	YAP1	0	affinity chromatography technology	Rodriguez J (2016)	1
CEP135	2	TRIM27	2	affinity chromatography technology	Hein MY (2015)	1
HSP90AA1	7	IKBKG	0	affinity chromatography technology, affinity chromatography technology	Gano JJ (2010), Hein MY (2015)	2
HNRNPL	3	APP	1	affinity chromatography technology	Fei T (2017)	1
TNIP1	1	TBK1	1	affinity chromatography technology, affinity chromatography technology	Gao L (2011), Gao L (2011)	2
HIF1AN	0	AZI2	1	affinity chromatography technology	Rodriguez J (2016)	1
NFKB1	2	TNFAIP3	3	affinity chromatography technology	Lapid D (2017)	1
NFKB1	2	REL	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Huttlin EL (2015), Li X (2015), Huttlin EL (2017)	4
SOCS3	0	REL	5	affinity chromatography technology, affinity chromatography technology	Nair S (2011), Nair S (2011)	2
NEDD4	2	LATS2	1	affinity chromatography technology	Bae SJ (2015)	1
TRAF2	1	TRAF3IP2	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Qian Y (2004), Sun D (2011)	3
TLR9	2	TRAF6	0	affinity chromatography technology	Yang M (2011)	1
HERC2	9	TANK	1	affinity chromatography technology	Al-Hakim AK (2012)	1
IRF3	4	IRF7	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Au WC (2001), Au WC (2001), Higgs R (2008), Higgs R (2008)	4
TMEM173	0	IKBKE	2	affinity chromatography technology	Zhang Q (2017)	1
TRAF2	1	IFIT3	1	affinity chromatography technology	Liu XY (2011)	1
GSK3B	1	NFKB1	2	enzymatic study	Demarchi F (2001)	1
CDC37	0	APP	1	two hybrid	Soler-Lopez M (2011)	1
TNF	0	TNFAIP3	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Skaug B (2011), Tokunaga F (2012), Verhelst K (2012), Yamaguchi N (2015), Draber P (2015)	5
LATS2	1	TRIM27	2	bioid	Couzens AL (2013)	1
HSP90AA1	7	SKP1	0	pull down	Zhang M (2008)	1
CEP128	1	CYLD	2	bioid	Gupta GD (2015)	1
TANK	1	APP	1	pull down	Olah J (2011)	1
CEP63	2	TXLNG	1	bioid	Gupta GD (2015)	1
TRIM26	1	TBK1	1	affinity chromatography technology, affinity chromatography technology	Ran Y (2016), Ran Y (2016)	2
NCK1	0	TBK1	1	pull down, affinity chromatography technology	Chou MM (1995), Chou MM (1995)	2
TRAF2	1	SMURF1	4	genetic interference	Li S (2010)	1
CLEC14A	1	LETM1	6	affinity chromatography technology	Zanivan S (2013)	1
NFKB2	3	BTRC	1	affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, bioid	Fong A (2002), Vatsyayan J (2008), Liang C (2006), Liang C (2006), Xiao G (2004), Amir RE (2004), Busino L (2012), Coyaud E (2015), Coyaud E (2015)	9
EGFR	5	AKT1	1	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
TRAF3IP2	0	TRAF6	0	enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid	Liu C (2009), Kanamori M (2002), Kanamori M (2002), Kanamori M (2002), Qian Y (2007), Qu F (2012), Wu NL (2014), Wu NL (2014), Rolland T (2014), Garg AV (2013), Sun D (2011), Yu H (2011)	12
TLR4	5	TRAF6	0	affinity chromatography technology	Yang M (2011)	1
USP2	0	TRAIP	0	two hybrid	Hayes SD (2012)	1
TICAM1	3	TRAF3	1	affinity chromatography technology, affinity chromatography technology	Jiang Z (2004), Nguyen VP (2014)	2
TRAF2	1	RB1CC1	9	affinity chromatography technology	Gan B (2006)	1
GSK3B	1	RELA	1	affinity chromatography technology	Neumann M (2011)	1
OFD1	3	TXLNA	3	bioid	Gupta GD (2015)	1
USP2	0	IKBKG	0	enzymatic study	Zhou H (2004)	1
TRAF1	0	SQSTM1	0	affinity chromatography technology	Greenfeld H (2015)	1
CEP44	2	PPP6C	7	bioid	Gupta GD (2015)	1
TRAF1	0	SKP1	0	affinity chromatography technology	Greenfeld H (2015)	1
NLRP4	5	HSP90AA1	7	affinity chromatography technology	Mayor A (2007)	1
IKBKG	0	NFKBIA	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Stempin CC (2011), Pringle LM (2011), Wu CJ (2006), Higashimoto T (2008), Ducut Sigala JL (2004), Shibata Y (2011), Liu L (2002), Xiao G (2000), Chan H (2005), Funakoshi-Tago M (2005), Wu X (2007), Kato T (2008), Niu J (2011), Neumann M (2011), Keusekotten K (2013), Fu J (2013), Dan HC (2008), Criollo A (2010), Hein MY (2015), Baratchian M (2016)	20
SMURF1	4	XPO1	8	affinity chromatography technology	Tajima Y (2003)	1
CDC37	0	SQSTM1	0	two hybrid, affinity chromatography technology	Vinayagam A (2011), Li J (2013)	2
ESR1	0	TRAF3	1	affinity chromatography technology, affinity chromatography technology	Wang C (2015), Wang C (2015)	2
NTRK1	1	RELA	1	affinity chromatography technology	Emdal KB (2015)	1
BTRC	1	REL	5	affinity chromatography technology, bioid	Coyaud E (2015), Coyaud E (2015)	2
IKBKE	2	TRAF3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ng MH (2011), Charoenthongtrakul S (2013), Peng Y (2014), Gu L (2017), Fang R (2017)	5
NTRK1	1	MIB1	5	affinity chromatography technology	Emdal KB (2015)	1
TBK1	1	FXR2	2	affinity chromatography technology	Li S (2011)	1
TBK1	1	CYLD	2	affinity chromatography technology, imaging technique, affinity chromatography technology	Friedman CS (2008), Genin P (2015), Genin P (2015)	3
RNF11	0	IKBKG	0	two hybrid	Colland F (2004)	1
RNF11	0	CALCOCO2	0	two hybrid	Colland F (2004)	1
PROS1	3	TBK1	1	two hybrid	Wang J (2011)	1
APP	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology, pull down	Zhou F (2012), Zhou F (2012), Olah J (2011)	3
AGO2	10	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Fabian MR (2009), Maniataki E (2005)	2
IKBKG	0	TBK1	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Fenner BJ (2010), Li S (2011), Wang L (2012), Wang L (2012), Ran Y (2016), Huttlin EL (2017)	7
TBK1	1	APP	1	pull down	Olah J (2011)	1
XPO1	8	CNTROB	6	affinity chromatography technology	Kirli K (2015)	1
PLK1	0	TBK1	1	affinity chromatography technology	Huttlin EL (2017)	1
TBK1	1	XIAP	0	enzymatic study, enzymatic study	Nakhaei P (2012), Kuranaga E (2006)	2
ESR1	0	TRAF6	0	affinity chromatography technology	Robinson LJ (2009)	1
CEP44	2	TBK1	1	bioid	Gupta GD (2015)	1
CYLD	2	TRAIP	0	two hybrid, far western blotting	Regamey A (2003), Regamey A (2003)	2
IKBKE	2	IRF3	4	affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study	Friedman CS (2008), Nakhaei P (2012), Bharaj P (2016), Zhang Q (2017)	4
CLEC14A	1	FMR1	1	affinity chromatography technology	Zanivan S (2013)	1
CEP135	2	CEP152	2	bioid	Gupta GD (2015)	1
AZI2	1	TXLNA	3	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
CEP44	2	ANKRD28	1	bioid	Gupta GD (2015)	1
IKBKE	2	TANK	1	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nomura F (2000), Nomura F (2000), Nomura F (2000), Gatot JS (2007), Renner F (2011), Shen RR (2012), Ryzhakov G (2007), So J (2015)	8
ODF2	1	APP	1	pull down	Olah J (2011)	1
TICAM1	3	TRAF5	1	affinity chromatography technology	Jiang Z (2004)	1
NFKBIA	0	NFKB1	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hay DC (2001), Malek S (1998), Fagan-Garcia K (2011), Jeon YJ (2010), Roff M (1996), Keutgens A (2010), Inan MS (2000), Wang J (2011), Arenzana-Seisdedos F (1995), Jaffray E (1995), Wood KM (1998), Bell S (1996), Cockman ME (2006), Cockman ME (2006), Lu Y (2005), Huttlin EL (2015), Hein MY (2015), Li X (2015), Huttlin EL (2017)	19
IRF3	4	TRAF2	1	affinity chromatography technology	Liu S (2015)	1
CDC37	0	SKP1	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
NTRK1	1	TXLNA	3	affinity chromatography technology	Emdal KB (2015)	1
SSX2IP	0	TRIM9	3	bioid	Gupta GD (2015)	1
TNFAIP3	3	TRAF1	0	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Song HY (1996), Song HY (1996), Heyninck K (1999), Greenfeld H (2015), Greenfeld H (2015)	5
NEDD4	2	SKP1	0	affinity chromatography technology	Liu J (2014)	1
TRAF6	0	TBK1	1	affinity chromatography technology, affinity chromatography technology, pull down	Cai B (2017), Fang R (2017), Fang R (2017)	3
TRAF3IP2	0	IRF3	4	affinity chromatography technology	Ryzhakov G (2012)	1
TBK1	1	IKBKE	2	affinity chromatography technology, pull down, affinity chromatography technology, pull down	Li S (2011), Ikeda F (2007), Liu D (2015), Liu D (2015)	4
TRAF6	0	SRC	2	affinity chromatography technology, pull down	Wong BR (1999), Liu A (2012)	2
IKBKG	0	TRIM26	1	affinity chromatography technology	Ran Y (2016)	1
NFKB2	3	RELA	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Scheinman RI (1993), Scheinman RI (1993), Yang CH (2005), Leung CH (2006)	5
TBK1	1	PBXIP1	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Shostak K (2014), Shostak K (2014), Shostak K (2014)	3
OFD1	3	TXLNG	1	bioid	Gupta GD (2015)	1
TLR3	2	TBK1	1	affinity chromatography technology, affinity chromatography technology	Yang M (2011), Zinngrebe J (2016)	2
HNRNPL	3	LATS2	1	affinity chromatography technology	Fei T (2017)	1
CLEC14A	1	FXR2	2	affinity chromatography technology	Zanivan S (2013)	1
PLK1	0	IKBKG	0	affinity chromatography technology, affinity chromatography technology	Zhang W (2010), Zhang W (2010)	2
CYLD	2	FMR1	1	affinity chromatography technology	Elliott PR (2016)	1
CYLD	2	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Kim JY (2009), Kim JY (2009)	2
MED4	2	SQSTM1	0	bioid	Lambert JP (2015)	1
DDX58	3	CYLD	2	affinity chromatography technology	Friedman CS (2008)	1
SRC	2	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Olayioye MA (1999), Keely SJ (2000), Sato K (2000), Lee CW (2007), Jaganathan S (2011), Jaganathan S (2011), Lee IT (2010), Hitosugi T (2007), Chang CC (2012), Chang CC (2012), Tung WH (2011), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Yao Z (2017)	15
TICAM1	3	MAVS	1	affinity chromatography technology	Xu LG (2005)	1
TBK1	1	NFKBIA	0	enzymatic study	Zhang W (2010)	1
IKBKE	2	TRAF2	1	enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Shen RR (2012), Shen RR (2012), Shen RR (2012), Zhang W (2010), Zhou AY (2013), Zhou AY (2013), So J (2015), Fang R (2017)	8
TRIM27	2	TBK1	1	affinity chromatography technology, enzymatic study	Zha J (2006), Zha J (2006)	2
APBA3	2	EGFR	5	unspecified method	Jones RB (2006)	1
XIAP	0	SSX2IP	0	two hybrid	Rolland T (2014)	1
CUL1	7	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Suzuki H (2000), Cenciarelli C (1999), Sowa ME (2009), Megumi Y (2005), Davis M (2002), Kawakami T (2001), Read MA (2000), Suzuki H (1999), Kumar KG (2007), Schweitzer K (2007), Chua YS (2011), Winston JT (1999), Winston JT (1999), Peschiaroli A (2010), Latres E (1999), Latres E (1999), Yoshida Y (2007), Bennett EJ (2010), Cui W (2012), Dehan E (2009), Busino L (2003), Chung FZ (2014), Chen ZW (2015), Kim TY (2014), Read MA (2000), Coyaud E (2015), Low TY (2014), Coyaud E (2015), He N (2005), Huttlin EL (2017), Kuang P (2016), Reitsma JM (2017), Reitsma JM (2017)	34
PPP6C	7	PPP6R1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Zeng K (2010), Douglas P (2010), Couzens AL (2013), Couzens AL (2013), Couzens AL (2013), St-Denis N (2016), Yadav L (2017)	7
EGFR	5	IKBKG	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
ODF2	1	TRIM9	3	bioid	Gupta GD (2015)	1
NTRK1	1	YWHAE	0	affinity chromatography technology	Emdal KB (2015)	1
SKP1	0	CCDC8	1	affinity chromatography technology	Hauri S (2016)	1
TANK	1	TRAF6	0	affinity chromatography technology, affinity chromatography technology, pull down	Wang W (2015), Wang W (2015), Wang W (2015)	3
HNRNPL	3	MBP	0	affinity chromatography technology	Fei T (2017)	1
EGLN3	0	MIB1	5	affinity chromatography technology	Rodriguez J (2016)	1
RNF11	0	USP2	0	affinity chromatography technology	Poulsen SL (2013)	1
EGFR	5	XIAP	0	affinity chromatography technology	Yao Z (2017)	1
HSP90AA1	7	APP	1	affinity chromatography technology	Kumar P (2007)	1
REL	5	NFKBIA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Spiecker M (2000), Chu ZL (1996), Chu ZL (1996), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
TRAF2	1	CYLD	2	two hybrid, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kovalenko A (2003), Kovalenko A (2003), Kovalenko A (2003), Kovalenko A (2003), Yang Y (2013), Elliott PR (2016), Wu GR (2017)	7
XPO1	8	TICAM1	3	affinity chromatography technology	Kirli K (2015)	1
TRIM23	3	TRAF1	0	two hybrid	Rolland T (2014)	1
TRAF1	0	TBK1	1	affinity chromatography technology, affinity chromatography technology	Greenfeld H (2015), Huttlin EL (2017)	2
TBK1	1	MIB1	5	affinity chromatography technology, pull down, enzymatic study	Li S (2011), Li S (2011), Li S (2011)	3
STIL	3	SSX2IP	0	bioid	Gupta GD (2015)	1
TICAM1	3	TBK1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li S (2011), Piao W (2009), Sato S (2003), Sato S (2003), Hu YH (2015), Cai B (2017)	6
AKT1	1	ESR1	0	enzymatic study	Campbell RA (2001)	1
SCLT1	1	TBK1	1	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
BBOX1	0	TANK	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TRIM27	2	IKBKE	2	affinity chromatography technology, enzymatic study	Zha J (2006), Zha J (2006)	2
DDX58	3	IRF3	4	affinity chromatography technology, affinity chromatography technology	Friedman CS (2008), Xu LG (2005)	2
TBK1	1	FMR1	1	affinity chromatography technology	Li S (2011)	1
USP2	0	TRIM27	2	two hybrid, two hybrid	Hayes SD (2012), Rolland T (2014)	2
TNF	0	TNIP1	1	affinity chromatography technology	Haas TL (2009)	1
EGLN3	0	PPP6C	7	affinity chromatography technology	Rodriguez J (2016)	1
HIF1AN	0	SKP1	0	affinity chromatography technology	Rodriguez J (2016)	1
APP	1	IFIT3	1	two hybrid, affinity chromatography technology	Soler-Lopez M (2011), Soler-Lopez M (2011)	2
IKBKG	0	TRAF3IP2	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down	Leonardi A (2000), Li X (2000), Mauro C (2003), Mauro C (2003), Mauro C (2003)	5
NFKB1	2	BTRC	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Heissmeyer V (2001), Lang V (2003), Lang V (2003), Winston JT (1999), Winston JT (1999), Busino L (2012), Amir RE (2002), Coyaud E (2015), Coyaud E (2015), Zhang Z (2015), Huttlin EL (2017)	11
MCM2	3	TOMM70	1	affinity chromatography technology	Drissi R (2015)	1
NTRK1	1	PPP6C	7	affinity chromatography technology	Emdal KB (2015)	1
TRAF1	0	CUL1	7	affinity chromatography technology	Huttlin EL (2017)	1
SOCS3	0	RELA	1	affinity chromatography technology, affinity chromatography technology	Nair S (2011), Nair S (2011)	2
IKBKE	2	TRAF3IP2	0	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Qu F (2012), Qu F (2012), Qu F (2012), Ryzhakov G (2012)	4
XIAP	0	AKT1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique	Dan HC (2004), Dan HC (2004), Pramanik KC (2013), Pramanik KC (2013), Chen TC (2014)	5
TICAM1	3	TANK	1	affinity chromatography technology	Li S (2011)	1
NFKBIA	0	SRC	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SYK	3	TRAIP	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Zhou Q (2009), Zhou Q (2009), Zhou Q (2009)	3
TRAF2	1	XIAP	0	affinity chromatography technology	Vince JE (2009)	1
TNF	0	CYLD	2	affinity chromatography technology, affinity chromatography technology	Draber P (2015), Schlicher L (2016)	2
TLR3	2	TRAF3	1	affinity chromatography technology	Li S (2011)	1
CALCOCO2	0	RB1CC1	9	two hybrid	Wang J (2011)	1
IKBKG	0	TRAF3	1	affinity chromatography technology	Belgnaoui SM (2012)	1
SQSTM1	0	TAX1BP1	3	affinity chromatography technology	Mildenberger J (2017)	1
EGLN3	0	ATG9A	5	affinity chromatography technology	Rodriguez J (2016)	1
HIF1AN	0	FMR1	1	affinity chromatography technology	Rodriguez J (2016)	1
HSP90AA1	7	IKBKE	2	affinity chromatography technology	Taipale M (2012)	1
NTRK1	1	OFD1	3	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	HNRNPL	3	affinity chromatography technology	Emdal KB (2015)	1
TRAF6	0	XIAP	0	affinity chromatography technology, two hybrid, imaging technique	Sanna MG (2002), Woodsmith J (2012), Chen TC (2014)	3
DYRK2	1	TBK1	1	affinity chromatography technology, affinity chromatography technology	An T (2015), An T (2015)	2
OPTN	1	IKBKG	0	affinity chromatography technology	Nakazawa S (2016)	1
AZI2	1	TBK1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Li S (2011), Li S (2011), Fujita F (2003), Fujita F (2003), Fujita F (2003), Fujita F (2003), Ryzhakov G (2007), Seo S (2013)	8
TLR4	5	TBK1	1	affinity chromatography technology	Yang M (2011)	1
CALCOCO2	0	SQSTM1	0	affinity chromatography technology	Cemma M (2011)	1
TRAF3	1	MAVS	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nakhaei P (2009), Arnaud N (2011), Paz S (2011), Wang Y (2012), Saha SK (2006), Saha SK (2006), Ng MH (2011), Johnsen IB (2009), van Zuylen WJ (2012), Belgnaoui SM (2012), Chen X (2014), Wang P (2013), Wang P (2013), Minassian A (2015), Gu L (2017), Khan M (2016), Fang R (2017), Fang R (2017)	18
TRIM9	3	TRIM27	2	two hybrid	Woodsmith J (2012)	1
IKBKG	0	CYLD	2	two hybrid, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Kovalenko A (2003), Kovalenko A (2003), Kovalenko A (2003), Kovalenko A (2003), Brummelkamp TR (2003), Trompouki E (2003), Chu L (2006), Shibata Y (2012), Wang J (2011), Zilberman-Rudenko J (2016), Zilberman-Rudenko J (2016)	11
ODF2	1	CEP135	2	bioid	Gupta GD (2015)	1
MCM2	3	SKP1	0	affinity chromatography technology	Drissi R (2015)	1
TRAF5	1	TRAF3IP2	0	affinity chromatography technology, affinity chromatography technology	Sun D (2011), Sun D (2011)	2
DDX58	3	SRC	2	affinity chromatography technology	Johnsen IB (2009)	1
NFKB1	2	NFKB2	3	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Bouwmeester T (2004), Bouwmeester T (2004), Wang J (2011), Li X (2015)	4
XPO1	8	HIF1AN	0	affinity chromatography technology	Kirli K (2015)	1
IKBKE	2	CDC37	0	affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Li S (2011)	2
SYK	3	TBK1	1	affinity chromatography technology	Lin YC (2013)	1
PLK1	0	RELA	1	pull down	Lin DC (2011)	1
MAVS	1	IFIT3	1	affinity chromatography technology, affinity chromatography technology	Liu XY (2011), Liu XY (2011)	2
CEP128	1	TXLNA	3	bioid	Gupta GD (2015)	1
IKBKG	0	TRIM23	3	affinity chromatography technology, affinity chromatography technology	Arimoto K (2010), Arimoto K (2010)	2
TXLNB	0	MED4	2	affinity chromatography technology	Huttlin EL (2017)	1
TBK1	1	NFKB2	3	affinity chromatography technology	Bouwmeester T (2004)	1
DDX58	3	IKBKG	0	affinity chromatography technology	Oshiumi H (2013)	1
HNRNPL	3	SMURF1	4	affinity chromatography technology	Fei T (2017)	1
IRF3	4	HSP90AA1	7	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Yang K (2006), Yang K (2006), Yang K (2006), Liu XY (2010), Liu XY (2010)	5
HSP90AA1	7	XPO1	8	affinity chromatography technology	Falsone SF (2005)	1
STX12	2	TBK1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
WHRN	1	ANKRD28	1	affinity chromatography technology	Boldt K (2016)	1
TNFAIP3	3	IRF7	2	affinity chromatography technology, affinity chromatography technology	Ning S (2010), Ning S (2010)	2
HNRNPL	3	SRC	2	affinity chromatography technology	Fei T (2017)	1
AKT1	1	GSK3B	1	pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Thimmaiah KN (2005), Drendall CI (2010), Connor MK (2005), Hunter MG (2004), Zhu QS (2011), Li L (2003), Nam SY (2010), Yang WL (2009), Zeng L (2013), Yang H (2005), Boehme KA (2008), Cross DA (1995), Hinton CV (2007), Kapoor GS (2004), Pitre A (2012), Guo J (2016)	16
TBK1	1	CUL1	7	affinity chromatography technology	Bouwmeester T (2004)	1
SRC	2	SYK	3	enzymatic study, affinity chromatography technology, enzymatic study	Kurosaki T (1994), Asazuma N (1997), Hirose M (2004)	3
TRAF3	1	TNIP1	1	affinity chromatography technology	Gao L (2011)	1
STX11	1	APP	1	pull down	Olah J (2011)	1
MAP1LC3B	1	SQSTM1	0	two hybrid, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, x-ray crystallography, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stelzl U (2005), Behrends C (2010), Vinayagam A (2011), Kirkin V (2009), Kirkin V (2009), Liang X (2013), Liang X (2013), Novak I (2010), Novak I (2010), Rogov VV (2012), Gao W (2013), Maruyama Y (2014), Maruyama Y (2014), Maruyama Y (2014), Yamashita SI (2014), Wurzer B (2015), Wurzer B (2015), Wurzer B (2015), Sun A (2017), Cohen-Kaplan V (2016), Dou Z (2015), Galindo-Moreno M (2017)	22
EGLN3	0	ANKRD28	1	affinity chromatography technology	Rodriguez J (2016)	1
CEP152	2	TNIP1	1	bioid	Gupta GD (2015)	1
NFKB1	2	RELA	1	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, imaging technique, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Palvimo JJ (1996), Dhar SK (2006), Williams SA (2006), Williams SA (2006), Hassa PO (2005), Hassa PO (2005), Sasaki CY (2005), Jeon YJ (2010), Urban MB (1991), Beauchef G (2012), Ryo A (2003), Burstein E (2005), Beinke S (2002), Sharif-Askari E (2010), Mifflin RC (2002), Nie M (2003), Nehra R (2010), Wang J (2011), Mellits KH (1993), Gallois C (1998), Milanovic M (2013), Milanovic M (2013), Kwon JH (2003), Cimen I (2011), Saha RN (2007), Wi SM (2014), Wi SM (2014), Hochrainer K (2012), Longoni N (2013), Li X (2015)	31
TLR9	2	TRAF3	1	affinity chromatography technology	Li S (2011)	1
TRIM14	1	PPP6C	7	two hybrid, affinity chromatography technology, bioid	Tan P (2017), Tan P (2017), Tan P (2017)	3
TBK1	1	IFIT3	1	affinity chromatography technology, affinity chromatography technology	Liu XY (2011), Liu XY (2011)	2
BTRC	1	SKP1	0	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Suzuki H (2000), Strack P (2000), Margottin F (1998), Cenciarelli C (1999), Cenciarelli C (1999), Cenciarelli C (1999), Watanabe N (2004), Wu G (2003), Kawakami T (2001), Hattori K (1999), Hattori K (1999), Hattori K (1999), Kitagawa M (1999), Hart M (1999), Su Y (2008), Banerjee S (2010), Winston JT (1999), Winston JT (1999), Estrabaud E (2007), Latres E (1999), Latres E (1999), Liu J (2004), Lievens S (2009), Yoshida Y (2007), Yoshida Y (2007), Busino L (2012), Li T (2005), da Silva Almeida AC (2013), Sahasrabuddhe AA (2014), Choi BH (2014), Chong RA (2014), Kim TY (2014), Coyaud E (2015), Deng W (2015), Coyaud E (2015), Liu YQ (2015), He N (2005), Kuchay S (2017), Hauri S (2016)	40
TXLNA	3	TXLNB	0	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	Li S (2011), Li S (2011), Rolland T (2014), Huttlin EL (2017)	4
AZI2	1	MIB1	5	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
TBK1	1	PELI1	1	enzymatic study, affinity chromatography technology	Smith H (2011), Murphy M (2015)	2
TNF	0	NFKBIA	0	enzymatic study	Rodriguez MS (1995)	1
AKT1	1	SRC	2	imaging technique, affinity chromatography technology	Chen TC (2014), Lee J (2013)	2
CEP128	1	NINL	1	bioid	Gupta GD (2015)	1
AKT1	1	RNF11	0	enzymatic study	Connor MK (2005)	1
ESR1	0	HSP90AA1	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nair SC (1996), Lee MO (2002), Fan M (2005), Tateishi Y (2004), Fiskus W (2007), Powell E (2010), Suzuki T (2011), Berry NB (2008), Sumanasekera WK (2003), Taipale M (2012), Donley C (2013), Donley C (2013), Dhamad AE (2016)	13
TRAIP	0	TBK1	1	affinity chromatography technology	Zhang M (2012)	1
MED4	2	CEP152	2	bioid	Lambert JP (2015)	1
CYLD	2	AKT1	1	enzymatic study, affinity chromatography technology	Yang WL (2013), Yang WL (2013)	2
IKBKG	0	IKBKE	2	affinity chromatography technology, affinity chromatography technology	Zhao T (2007), Zhou AY (2013)	2
CEP135	2	SQSTM1	0	bioid	Gupta GD (2015)	1
CEP63	2	TXLNB	0	two hybrid, affinity chromatography technology	Rolland T (2014), Huttlin EL (2017)	2
SKP1	0	ESR1	0	affinity chromatography technology	Zhou W (2014)	1
MED4	2	CYLD	2	bioid	Lambert JP (2015)	1
TLR3	2	SYK	3	affinity chromatography technology	Lin YC (2013)	1
TNFAIP3	3	TRAF2	1	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Song HY (1996), Song HY (1996), Fries KL (1999), Yamaguchi N (2013), Rolland T (2014)	5
IKBKG	0	AKT1	1	pull down, affinity chromatography technology	Fenner BJ (2010), Hou Y (2010)	2
CEP135	2	PLK1	0	bioid	Gupta GD (2015)	1
HNRNPL	3	TBK1	1	affinity chromatography technology	Fei T (2017)	1
RNF11	0	TNIP1	1	two hybrid	Colland F (2004)	1
IRF3	4	TOMM70	1	affinity chromatography technology, affinity chromatography technology, pull down	Liu XY (2010), Liu XY (2010), Liu XY (2010)	3
CEP63	2	SSX2IP	0	bioid	Gupta GD (2015)	1
ESR1	0	IKBKE	2	affinity chromatography technology	Wang C (2015)	1
LATS2	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSP90AA1	7	TBK1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang K (2006), Taipale M (2012), Liu XY (2010)	3
ANKRD28	1	TBKBP1	2	bioid	Couzens AL (2013)	1
EGLN3	0	YWHAE	0	affinity chromatography technology	Rodriguez J (2016)	1
IKBKG	0	STX11	1	two hybrid	Wang J (2011)	1
CUL1	7	HNRNPL	3	affinity chromatography technology	Bennett EJ (2010)	1
TRAF6	0	IKBKE	2	affinity chromatography technology	Fang R (2017)	1
MCM2	3	PLK1	0	affinity chromatography technology	Boldt K (2016)	1
MAVS	1	TRAF5	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Tang ED (2010), Tang ED (2010), Minassian A (2015), Khan M (2016)	4
NFKB2	3	REL	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Scheinman RI (1993), Huttlin EL (2015), Huttlin EL (2017)	4
XPO1	8	PPP6R1	4	affinity chromatography technology	Kirli K (2015)	1
TLR4	5	SYK	3	affinity chromatography technology	Lin YC (2013)	1
CDC37	0	AKT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Basso AD (2002), Basso AD (2002), Kim H (2014), Sun L (2012)	4
EGFR	5	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Citri A (2002), Yang S (2006), Shimamura T (2005), Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014)	8
CLEC14A	1	TBK1	1	affinity chromatography technology	Zanivan S (2013)	1
NTRK1	1	XPO1	8	affinity chromatography technology	Emdal KB (2015)	1
MBP	0	DDX58	3	affinity chromatography technology, affinity chromatography technology	Feng M (2012), Feng M (2012)	2
CEP128	1	ANKRD28	1	bioid	Gupta GD (2015)	1
CNTROB	6	CYLD	2	bioid	Gupta GD (2015)	1
CYLD	2	TRAF6	0	enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kovalenko A (2003), Bremm A (2010), Wu J (2015), Wu J (2015)	4
TBK1	1	PPP6C	7	affinity chromatography technology	Bouwmeester T (2004)	1
HIF1AN	0	ANKRD28	1	affinity chromatography technology	Rodriguez J (2016)	1
XPO1	8	CYLD	2	affinity chromatography technology	Kirli K (2015)	1
TBK1	1	TRAF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Bouwmeester T (2004), Bonnard M (2000), Behrends C (2010), Li S (2011), Li S (2011), Shen RR (2012), Zhang W (2010), Huttlin EL (2017), Fang R (2017), Fang R (2017)	10
CEP128	1	MIB1	5	bioid	Gupta GD (2015)	1
TICAM1	3	TRAF6	0	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology	Sasai M (2010), Sasai M (2010), Jiang Z (2004), Wang YY (2004), Sato S (2003), Sato S (2003), Sato S (2003), Takaki H (2009), Verstak B (2014), Hu YH (2015)	10
USP2	0	TRIM9	3	two hybrid	Hayes SD (2012)	1
TANK	1	TRAF2	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, unspecified method	Bouwmeester T (2004), Rothe M (1996), Rothe M (1996), Nomura F (2000), Nomura F (2000), Pomerantz JL (1999), Behrends C (2010), Li S (2011), Li S (2011), Li C (2002), Shen RR (2012), Shen RR (2012), Wang J (2011), Huttlin EL (2017), Kim CM (2017)	15
SASS6	1	CEP152	2	bioid	Gupta GD (2015)	1
TBK1	1	TXLNG	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Li S (2011), Li S (2011), Li S (2011), Li S (2011)	4
FXR2	2	CEP44	2	two hybrid	Rolland T (2014)	1
YAP1	0	EGFR	5	affinity chromatography technology	Komuro A (2003)	1
SASS6	1	OFD1	3	bioid	Gupta GD (2015)	1
CDC37	0	SRC	2	pull down	Rao J (2001)	1
TBK1	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Qin Y (2016), Qin Y (2016)	2
CEP128	1	TBK1	1	bioid	Gupta GD (2015)	1
SMURF1	4	TBK1	1	enzymatic study	Andrews PS (2010)	1
HNRNPL	3	YWHAE	0	biochemical, affinity chromatography technology	Wan C (2015), Fei T (2017)	2
IKBKG	0	TRIM14	1	affinity chromatography technology, pull down, affinity chromatography technology	Zhou Z (2014), Zhou Z (2014), Zhou Z (2014)	3
NTRK1	1	TOMM70	1	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	MCM2	3	affinity chromatography technology	Emdal KB (2015)	1
CCDC8	1	XPO1	8	affinity chromatography technology	Hanson D (2014)	1
TBK1	1	NLRP4	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cui J (2012), Cui J (2012), An T (2015)	3
SQSTM1	0	MBP	0	pull down	Pridgeon JW (2004)	1
TNIP1	1	MAP1LC3B	1	two hybrid	Rolland T (2014)	1
HSP90AA1	7	DTX4	7	affinity chromatography technology	Taipale M (2012)	1
MAVS	1	TRAF1	0	affinity chromatography technology	Minassian A (2015)	1
TLR4	5	TRAF3	1	affinity chromatography technology	Li S (2011)	1
SYK	3	TRAF6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yamada T (2001), Lin YC (2013), Wu NL (2014)	3
MCM2	3	TBK1	1	affinity chromatography technology	Drissi R (2015)	1
HERC2	9	TXLNG	1	affinity chromatography technology	Galligan JT (2015)	1
TBK1	1	REL	5	affinity chromatography technology	Bouwmeester T (2004)	1
RB1CC1	9	TBK1	1	affinity chromatography technology, genetic interference	Behrends C (2010), Goodwin JM (2017)	2
TNF	0	IKBKG	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Haas TL (2009), Ea CK (2006), Tokunaga F (2012), Verhelst K (2012), Draber P (2015), Pescatore A (2016)	6
TRAF2	1	TRAF6	0	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, affinity chromatography technology	Rual JF (2005), Li S (2011), Davies CC (2005), Relaix F (1998), Rolland T (2014), Yu H (2011), Huttlin EL (2017)	7
XPO1	8	RELA	1	affinity chromatography technology	Kirli K (2015)	1
TBK1	1	PPP6R2	3	affinity chromatography technology	Bouwmeester T (2004)	1
MED4	2	MIB1	5	bioid	Lambert JP (2015)	1
CEP63	2	TBK1	1	bioid	Gupta GD (2015)	1
HSP90AA1	7	AKT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Haendeler J (2003), Kawauchi K (2005), Sato S (2000), Basso AD (2002), Su CH (2011), Klein JB (2005), Sun L (2012)	7
TRAF1	0	TNIP1	1	affinity chromatography technology	Greenfeld H (2015)	1
DDX58	3	IKBKE	2	affinity chromatography technology	Oshiumi H (2013)	1
DTX4	7	TBK1	1	affinity chromatography technology	Cui J (2012)	1
IKBKE	2	3324	0	affinity chromatography technology	Bouwmeester T (2004)	1
XPO1	8	PPP6R2	3	affinity chromatography technology	Kirli K (2015)	1
TRAF5	1	TBK1	1	affinity chromatography technology, pull down	Fang R (2017), Fang R (2017)	2
TRAF3	1	TRIM14	1	affinity chromatography technology	Zhou Z (2014)	1
STX11	1	TBK1	1	two hybrid, affinity chromatography technology	Wang J (2011), Huttlin EL (2017)	2
IKBKE	2	RNF11	0	affinity chromatography technology, affinity chromatography technology	Charoenthongtrakul S (2013), Charoenthongtrakul S (2013)	2
HNRNPL	3	EGFR	5	affinity chromatography technology	Fei T (2017)	1
DDX58	3	PPP6C	7	affinity chromatography technology, imaging technique	Tan P (2017), Tan P (2017)	2
LATS2	1	NINL	1	bioid	Couzens AL (2013)	1
CEP44	2	TXLNA	3	two hybrid	Rolland T (2014)	1
HIF1AN	0	MIB2	7	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	CDC37	0	affinity chromatography technology	Rodriguez J (2016)	1
TRAF5	1	TRAF2	1	affinity chromatography technology, pull down, pull down	Li S (2011), Li S (2011), Pullen SS (1998)	3
EGFR	5	HERC2	9	affinity chromatography technology	Yao Z (2017)	1
IKBKE	2	NFKBIA	0	enzymatic study	Zhang W (2010)	1
SASS6	1	STIL	3	affinity chromatography technology, affinity chromatography technology, bioid	Arquint C (2012), Arquint C (2012), Gupta GD (2015)	3
EGLN3	0	PPP6R2	3	affinity chromatography technology	Rodriguez J (2016)	1
HSP90AA1	7	BTRC	1	affinity chromatography technology	Taipale M (2012)	1
SSX2IP	0	OFD1	3	bioid, bioid, affinity chromatography technology	Gupta GD (2015), Gupta GD (2015), Hein MY (2015)	3
PPP6R1	4	PPP6R2	3	bioid, bioid	Couzens AL (2013), Couzens AL (2013)	2
SASS6	1	TBK1	1	bioid	Gupta GD (2015)	1
TLR9	2	SYK	3	affinity chromatography technology	Lin YC (2013)	1
IKBKE	2	MBP	0	enzymatic study	Ikeda F (2007)	1
EGLN3	0	SKP1	0	affinity chromatography technology	Rodriguez J (2016)	1
NFKB1	2	IKBKG	0	affinity chromatography technology, pull down	Bouwmeester T (2004), Smolle M (2004)	2
CEP135	2	TBK1	1	bioid	Gupta GD (2015)	1
OFD1	3	TNIP1	1	bioid	Gupta GD (2015)	1
TOMM70	1	HSP90AA1	7	affinity chromatography technology, pull down	Liu XY (2010), Liu XY (2010)	2
TNFAIP3	3	YWHAE	0	affinity chromatography technology, two hybrid	Vincenz C (1996), Wang J (2011)	2
EGLN3	0	XPO1	8	affinity chromatography technology	Rodriguez J (2016)	1
IKBKG	0	CDC37	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Chen G (2002), Taipale M (2014), Taipale M (2014), Liu D (2014), Hein MY (2015), Hein MY (2015), Li J (2013)	8
TRAIP	0	APP	1	pull down	Olah J (2011)	1
TICAM1	3	TRAF1	0	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid	Jiang Z (2004), Su X (2006), Su X (2006), Su X (2006), Takaki H (2009)	5
HIF1AN	0	TANK	1	affinity chromatography technology	Rodriguez J (2016)	1
CEP128	1	TXLNG	1	bioid	Gupta GD (2015)	1
STX19	3	TRIM9	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CEP63	2	CEP44	2	bioid	Gupta GD (2015)	1
MED4	2	CNTROB	6	bioid	Lambert JP (2015)	1
IRF3	4	TRIM26	1	affinity chromatography technology, pull down, enzymatic study	Wang P (2015), Wang P (2015), Wang P (2015)	3
TBK1	1	MAVS	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Li S (2011), Xu LG (2005), Wang L (2012), Liu XY (2011), Liu S (2015), Fang R (2017), Zhang Q (2017)	7
BTRC	1	CEP44	2	affinity chromatography technology	Loveless TB (2015)	1
APP	1	SRC	2	affinity chromatography technology	Austin SA (2009)	1
TRAF6	0	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sanz L (2000), Sanz L (2000), Nakamura K (2010), Kim JY (2009), Seibenhener ML (2004), Feng Y (2005), Martin P (2006), Martin P (2006), Geetha T (2012), Geetha T (2012), Linares JF (2013), Linares JF (2011), Linares JF (2015), Schimmack G (2017), Tsai WT (2016)	15
XPO1	8	SQSTM1	0	affinity chromatography technology	Kirli K (2015)	1
MAVS	1	SRC	2	affinity chromatography technology	Johnsen IB (2009)	1
IKBKG	0	TAX1BP1	3	two hybrid	Wang J (2011)	1
CYLD	2	MIB2	7	affinity chromatography technology, affinity chromatography technology, enzymatic study	Rajan N (2014), Rajan N (2014), Rajan N (2014)	3
ODF2	1	PLK1	0	bioid	Gupta GD (2015)	1
STX19	3	TBK1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TBK1	1	HMMR	1	affinity chromatography technology	Li S (2011)	1
STIL	3	OFD1	3	bioid	Gupta GD (2015)	1
STX3	3	TXLNA	3	pull down, affinity chromatography technology, affinity chromatography technology	Nogami S (2003), Huttlin EL (2015), Huttlin EL (2017)	3
IKBKE	2	TNFAIP3	3	affinity chromatography technology, affinity chromatography technology	Gao L (2011), Saitoh T (2005)	2
HERPUD1	2	APP	1	pull down	Olah J (2011)	1
SQSTM1	0	CUL1	7	affinity chromatography technology	Tanji K (2012)	1
TNF	0	TRAF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Micheau O (2003), Kuai J (2004), Kuai J (2004), Haas TL (2009), Ea CK (2006), Fritsch J (2014), Yamaguchi N (2015)	7
ESR1	0	FMR1	1	affinity chromatography technology	Tarallo R (2011)	1
SYK	3	TRAF3IP2	0	affinity chromatography technology, affinity chromatography technology	Wu NL (2014), Wu NL (2014)	2
NTRK1	1	TXLNG	1	affinity chromatography technology	Emdal KB (2015)	1
ODF2	1	TNIP1	1	bioid	Gupta GD (2015)	1
CALCOCO2	0	IKBKG	0	two hybrid	Wang J (2011)	1
TXLNA	3	TXLNG	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Li S (2011), Li S (2011), Li S (2011), Li S (2011), Havugimana PC (2012), Huttlin EL (2017), Boldt K (2016)	7
TBK1	1	RBBP5	3	affinity chromatography technology	Li S (2011)	1
SMURF1	4	ODF2	1	enzymatic study	Andrews PS (2010)	1
CALCOCO2	0	MTPAP	2	affinity chromatography technology, pull down, affinity chromatography technology	Li S (2011), Li S (2011), Huttlin EL (2017)	3
CCDC8	1	HERC2	9	affinity chromatography technology	Hanson D (2014)	1
HNRNPL	3	TRIM26	1	affinity chromatography technology	Fei T (2017)	1
TBK1	1	SKP1	0	affinity chromatography technology	Bouwmeester T (2004)	1
STIL	3	BTRC	1	bioid	Gupta GD (2015)	1
CEP128	1	CNTROB	6	bioid	Gupta GD (2015)	1
EGFR	5	STIL	3	affinity chromatography technology	Yao Z (2017)	1
TBK1	1	TBK1	1	enzymatic study, pull down, two hybrid, x-ray crystallography, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Piao W (2009), Ikeda F (2007), Ikeda F (2007), Tu D (2013), Tu D (2013), Tu D (2013), Seo S (2013), Liu D (2015), Qin Y (2016), Sparrer KMJ (2017)	10
TNIP1	1	NFKB1	2	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Cohen S (2009), Cohen S (2009), Wang J (2011), Li X (2015)	4
TXLNB	0	CEP135	2	affinity chromatography technology	Huttlin EL (2017)	1
AZI2	1	TXLNG	1	affinity chromatography technology	Li S (2011)	1
TRIM14	1	CUL1	7	bioid	Tan P (2017)	1
NTRK1	1	PPP6R2	3	affinity chromatography technology	Emdal KB (2015)	1
SKP1	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Staropoli JF (2003), Min KW (2003), Lisztwan J (1998), Zheng N (2002), Ohta T (1999), Bloom J (2006), Kumar R (2005), Megumi Y (2005), Wang W (2004), Read MA (2000), Wu K (2000), Tan P (1999), Mao X (2011), Lin HK (2009), Yano H (2008), Banerjee S (2010), Gao D (2010), Chua YS (2011), Zhang M (2008), Winston JT (1999), Latres E (1999), Latres E (1999), Arai T (2003), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), Emberley ED (2012), Bennett EJ (2010), Gastaldello S (2012), Michel JJ (1998), Michel JJ (1998), Michel JJ (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Furukawa M (2000), Furukawa M (2000), Liu J (2002), Liu J (2002), Liu J (2002), Yu ZK (1998), Yu ZK (1998), Postow L (2013), Cordero-Espinoza L (2013), Zhou W (2014), Zhou W (2014), Hao J (2015), Hao J (2015), Han XR (2016), Liu YQ (2015), Gorelik M (2016), Al-Yacoub N (2016), Reiterer V (2017), Hu Y (2017), Hauri S (2016), Reitsma JM (2017), Reitsma JM (2017), Chen F (2017)	59
TRAF6	0	TNFAIP3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, enzymatic study, two hybrid, two hybrid	Heyninck K (1999), Evans PC (2001), Lin SC (2008), Xiong Y (2011), Bremm A (2010), Kelly C (2012), Hayes SD (2012), Lin SC (2008), Garg AV (2013), Boone DL (2004), Schimmack G (2017), Schimmack G (2017)	12
CEP135	2	TXLNG	1	bioid	Gupta GD (2015)	1
PPP6R2	3	APP	1	pull down	Olah J (2011)	1
TAX1BP1	3	TBK1	1	affinity chromatography technology, affinity chromatography technology	Gao L (2011), Goodwin JM (2017)	2
RNF11	0	SMURF1	4	two hybrid	Colland F (2004)	1
MAVS	1	IKBKG	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tang ED (2010), Li S (2011), Li S (2011), Wang L (2012), Wang L (2012), Zhou Z (2014)	6
MED4	2	TXLNG	1	bioid, affinity chromatography technology	Lambert JP (2015), Lambert JP (2015)	2
CALCOCO2	0	TBKBP1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Thurston TL (2009), Li S (2011), Huttlin EL (2017)	3
LATS2	1	OFD1	3	bioid	Couzens AL (2013)	1
HIF1AN	0	REL	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Rodriguez J (2016)	2
HERC2	9	SSX2IP	0	affinity chromatography technology	Galligan JT (2015)	1
NINL	1	TBK1	1	bioid	Gupta GD (2015)	1
RNF11	0	APP	1	pull down	Olah J (2011)	1
MED4	2	TXLNA	3	two hybrid, bioid, affinity chromatography technology	Rolland T (2014), Lambert JP (2015), Lambert JP (2015)	3
GSK3B	1	HSP90AA1	7	enzymatic study	Muller P (2012)	1
YAP1	0	TBK1	1	affinity chromatography technology, affinity chromatography technology	Zhang Q (2017), Zhang Q (2017)	2
CEP63	2	CEP128	1	bioid, bioid, bioid	Firat-Karalar EN (2014), Gupta GD (2015), Gupta GD (2015)	3
XPO1	8	NFKB1	2	affinity chromatography technology	Kirli K (2015)	1
NEDD4	2	TBK1	1	pull down	Persaud A (2009)	1
NFKB2	3	USP2	0	affinity chromatography technology	Bouwmeester T (2004)	1
HIF1AN	0	TBK1	1	affinity chromatography technology	Huttlin EL (2017)	1
IKBKG	0	TRAF1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Greenfeld H (2015), Greenfeld H (2015), Abdul-Sater AA (2017)	3
NTRK1	1	AGO2	10	affinity chromatography technology	Emdal KB (2015)	1
TMEM173	0	TRAF2	1	affinity chromatography technology	Yao X (2016)	1
IRF3	4	MAVS	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Li S (2011), Wang Y (2012), Xu LG (2005), Liu S (2015), Liu S (2015), Zhou Z (2014)	6
TRIM14	1	NFKB1	2	bioid	Tan P (2017)	1
TRAF2	1	USP2	0	two hybrid, affinity chromatography technology, pull down, enzymatic study, two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Mahul-Mellier AL (2011), Mahul-Mellier AL (2011), Mahul-Mellier AL (2011), Rolland T (2014), Mahul-Mellier AL (2012), Mahul-Mellier AL (2012)	7
STIL	3	CDC37	0	bioid	Gupta GD (2015)	1
MED4	2	CEP135	2	bioid, bioid	Lambert JP (2015), Gupta GD (2015)	2
HNRNPL	3	XIAP	0	affinity chromatography technology	Fei T (2017)	1
EGFR	5	PPP6C	7	affinity chromatography technology	Foerster S (2013)	1
FXR2	2	FMR1	1	pull down, biochemical, affinity chromatography technology, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology	Siomi MC (1996), Siomi MC (1996), Ceman S (1999), Zhang Y (1995), Zhang Y (1995), Zhang Y (1995), Zhang Y (1995), Li S (2014), Li S (2014), Corominas R (2014), Rolland T (2014), Huttlin EL (2017)	12
CUL1	7	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
MAVS	1	IKBKE	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Paz S (2009), Li S (2011), Paz S (2011), Paz S (2011), Fang R (2017)	5
OFD1	3	CDC37	0	bioid	Gupta GD (2015)	1
OPTN	1	CYLD	2	two hybrid, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Nagabhushana A (2011), Nagabhushana A (2011), Nagabhushana A (2011), Genin P (2015), Genin P (2015)	5
SSX2IP	0	SCLT1	1	affinity chromatography technology	Gupta GD (2015)	1
TLR9	2	TBK1	1	affinity chromatography technology	Yang M (2011)	1
AZI2	1	TRAF3	1	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
SMURF1	4	ESR1	0	affinity chromatography technology, affinity chromatography technology, pull down	Ito I (2010), Ito I (2010), Ito I (2010)	3
CUL1	7	YWHAE	0	affinity chromatography technology	Bennett EJ (2010)	1
ANKRD28	1	PPP6R1	4	affinity chromatography technology, bioid, affinity chromatography technology, bioid	Couzens AL (2013), Couzens AL (2013), Couzens AL (2013), Couzens AL (2013)	4
ESR1	0	NCOA2	2	x-ray crystallography, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, two hybrid, pull down, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, unspecified method, two hybrid, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Waernmark A (2002), Waernmark A (2002), He B (2003), Fenne IS (2008), Fenne IS (2008), Cui Y (2006), Dutertre M (2003), Kindle KB (2005), Jaber BM (2004), Torchia J (1997), Yin H (2007), Monroe DG (2003), Bai Y (2003), Bramlett KS (2001), Kraichely DM (2000), Kraichely DM (2000), Eng FC (1998), Voegel JJ (1998), Nalvarte I (2010), Han SJ (2016), Han SJ (2016), MacPherson L (2009)	22
TNF	0	OPTN	1	affinity chromatography technology	Klingseisen L (2012)	1
CEP128	1	SCLT1	1	bioid	Gupta GD (2015)	1
BTRC	1	OFD1	3	bioid	Coyaud E (2015)	1
CEP152	2	CEP128	1	bioid, bioid	Firat-Karalar EN (2014), Gupta GD (2015)	2
USP2	0	TMEM173	0	affinity chromatography technology	Zhang M (2016)	1
TRAF1	0	TANK	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography	Rothe M (1996), Wang J (2011), Greenfeld H (2015), Huttlin EL (2017), Kim CM (2017), Kim CM (2017)	6
NFKBIA	0	NFKB2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
NTRK1	1	CUL1	7	affinity chromatography technology	Emdal KB (2015)	1
TRAF1	0	SRC	2	affinity chromatography technology, affinity chromatography technology	Wong BR (1999), Narita T (2005)	2
CUL1	7	ESR1	0	affinity chromatography technology	Zhou W (2014)	1
CEP63	2	TXLNA	3	two hybrid, bioid	Rolland T (2014), Gupta GD (2015)	2
HIF1AN	0	TXLNA	3	affinity chromatography technology	Huttlin EL (2017)	1
HIF1AN	0	PPP6R1	4	affinity chromatography technology	Rodriguez J (2016)	1
CEP135	2	TXLNA	3	bioid	Gupta GD (2015)	1
HSP90AA1	7	TNFAIP3	3	affinity chromatography technology	Taipale M (2012)	1
OFD1	3	PLK1	0	affinity chromatography technology, two hybrid, bioid	Wang J (2011), Wang J (2011), Gupta GD (2015)	3
RNF11	0	NEDD4	2	affinity chromatography technology, enzymatic study, two hybrid	Santonico E (2010), Persaud A (2009), Colland F (2004)	3
IKBKG	0	TRAF6	0	pull down, pull down, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Lamothe B (2008), Windheim M (2008), Lamothe B (2007), Gautheron J (2010), Gautheron J (2010), Hinz M (2010), Sebban-Benin H (2007), Zotti T (2014), Sun L (2004), Emmerich CH (2013), Zhou L (2014), Chen J (2015), Kim EK (2017), Medunjanin S (2016), Xing J (2016), Bal E (2017), Bal E (2017)	17
EGLN3	0	CYLD	2	affinity chromatography technology	Rodriguez J (2016)	1
YWHAE	0	TBK1	1	affinity chromatography technology, affinity chromatography technology	Zuo S (2010), Zuo S (2010)	2
ODF2	1	OFD1	3	bioid	Gupta GD (2015)	1
EGLN3	0	STIL	3	affinity chromatography technology	Rodriguez J (2016)	1
EGFR	5	SOCS3	0	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Xia L (2002), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
PLK1	0	MAVS	1	affinity chromatography technology	Huttlin EL (2017)	1
TNF	0	BTRC	1	affinity chromatography technology	Kuai J (2004)	1
CEP128	1	OFD1	3	bioid, affinity chromatography technology	Gupta GD (2015), Hein MY (2015)	2
TRAIP	0	TRAF1	0	two hybrid, pull down, affinity chromatography technology	Lee SY (1997), Lee SY (1997), Besse A (2007)	3
TRAF6	0	IFIT3	1	affinity chromatography technology	Liu XY (2011)	1
NTRK1	1	SRC	2	affinity chromatography technology	Emdal KB (2015)	1
YWHAE	0	CDC37	0	affinity chromatography technology	Zuo S (2010)	1
CCDC8	1	HNRNPL	3	affinity chromatography technology	Hanson D (2014)	1
HNRNPL	3	NCOA2	2	affinity chromatography technology	Fei T (2017)	1
CEP128	1	TRIM26	1	bioid	Gupta GD (2015)	1
TRAF2	1	TRAF3	1	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Li S (2011), He L (2004), He L (2004), Pullen SS (1998)	4
SKP1	0	NFKBIA	0	affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down	Hattori K (1999), Tan P (1999), Suzuki H (1999), Winston JT (1999), Surjit M (2012), Chong RA (2014)	6
USP2	0	TRAF6	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, two hybrid, enzymatic study	Bremm A (2010), Li Y (2013), Li Y (2013), Rolland T (2014), Li Y (2013)	5
ODF2	1	SSX2IP	0	bioid	Gupta GD (2015)	1
STIL	3	CUL1	7	bioid	Gupta GD (2015)	1
NFKBIA	0	HIF1AN	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017), Rodriguez J (2016)	3
NCK1	0	TRIM14	1	affinity chromatography technology	Hein MY (2015)	1
NTRK1	1	PLK1	0	affinity chromatography technology	Emdal KB (2015)	1
TBK1	1	CDC37	0	affinity chromatography technology	Bouwmeester T (2004)	1
TOMM70	1	TMEM173	0	affinity chromatography technology, affinity chromatography technology	Liu XY (2010), Liu XY (2010)	2
IFIT3	1	HNRNPL	3	affinity chromatography technology	Pichlmair A (2011)	1
NINL	1	TXLNG	1	bioid	Gupta GD (2015)	1
TRAF3IP2	0	TRAF3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Qian Y (2002), Qian Y (2004), Boisson B (2013)	3
BTRC	1	TRIM9	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology	Rual JF (2005), Shi M (2014), Shi M (2014), Shi M (2014), Kim TY (2014), Rolland T (2014), Coyaud E (2015), Loveless TB (2015), Loveless TB (2015), Coyaud E (2015), Huttlin EL (2017)	11
PLK1	0	ANKRD28	1	affinity chromatography technology	Svendsen JM (2009)	1
TNFAIP3	3	NFKB2	3	affinity chromatography technology	Yamaguchi N (2013)	1
XPO1	8	ESR1	0	affinity chromatography technology	Castoria G (2012)	1
EGFR	5	PLK1	0	affinity chromatography technology	Tong J (2014)	1
SSX2IP	0	MIB1	5	affinity chromatography technology	Gupta GD (2015)	1
BBOX1	0	TBK1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
USP2	0	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
XPO1	8	YAP1	0	affinity chromatography technology	Kirli K (2015)	1
TNIP1	1	TAX1BP1	3	affinity chromatography technology, affinity chromatography technology, two hybrid	Gao L (2011), Gao L (2011), Rolland T (2014)	3
XPO1	8	TBK1	1	affinity chromatography technology	Kirli K (2015)	1
TANK	1	IRF7	2	two hybrid, affinity chromatography technology	Gatot JS (2007), Gatot JS (2007)	2
CALCOCO2	0	TRAF6	0	two hybrid	Wang J (2011)	1
CYLD	2	3324	0	affinity chromatography technology	Elliott PR (2016)	1
CEP135	2	CEP44	2	bioid	Gupta GD (2015)	1
ODF2	1	TBK1	1	bioid	Gupta GD (2015)	1
AGO2	10	BTRC	1	unspecified method	Elcheva I (2009)	1
PPP6C	7	PPP6R2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zeng K (2010), Douglas P (2010), Couzens AL (2013), Couzens AL (2013), Couzens AL (2013), St-Denis N (2016), Huttlin EL (2017), Yadav L (2017)	8
CEP128	1	MED4	2	bioid	Gupta GD (2015)	1
TRAF6	0	APP	1	pull down	Olah J (2011)	1
TMEM173	0	MAVS	1	affinity chromatography technology, affinity chromatography technology	Wang Y (2012), Chen X (2014)	2
TRIM23	3	TNFAIP3	3	two hybrid	Rolland T (2014)	1
IKBKE	2	CALCOCO2	0	affinity chromatography technology	Thurston TL (2009)	1
TBK1	1	IRF3	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study	Friedman CS (2008), Li S (2011), Li S (2011), Cui J (2012), Piao W (2009), Nakhaei P (2012), Ikeda F (2007), Ikeda F (2007), Ng MH (2011), Wang L (2012), Yang K (2006), Yang K (2006), Liu XY (2010), Liu S (2015), Liu S (2015), Freischmidt A (2015), Zhang Q (2017), Zhang Q (2017)	18
IKBKG	0	CUL1	7	affinity chromatography technology	Orel L (2010)	1
NFKBIA	0	MAVS	1	affinity chromatography technology	Liu S (2015)	1
MAP1LC3B	1	NEDD4	2	affinity chromatography technology, pull down, pull down, x-ray crystallography	Sun A (2017), Sun A (2017), Qiu Y (2017), Qiu Y (2017)	4
ODF2	1	ANKRD28	1	bioid	Gupta GD (2015)	1
YAP1	0	BTRC	1	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Zhao B (2010), Zhao B (2010), Vinayagam A (2011), Huttlin EL (2017)	4
EGLN3	0	PLK1	0	affinity chromatography technology	Rodriguez J (2016)	1
NFKB1	2	TBK1	1	affinity chromatography technology	Bouwmeester T (2004)	1
MAP1LC3B	1	CALCOCO2	0	affinity chromatography technology	Verlhac P (2015)	1
HIF1AN	0	PPP6R2	3	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	TOMM70	1	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	TBK1	1	affinity chromatography technology	Rodriguez J (2016)	1
CYLD	2	CDC37	0	affinity chromatography technology	Elliott PR (2016)	1
TRAF3IP2	0	TBK1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Qu F (2012), Qu F (2012), Qu F (2012)	3
EGFR	5	TOMM70	1	affinity chromatography technology	Yao Z (2017)	1
LATS2	1	LETM1	6	affinity chromatography technology	Couzens AL (2013)	1
TBK1	1	RELA	1	affinity chromatography technology, enzymatic study, enzymatic study	Bouwmeester T (2004), Buss H (2004), Fujita F (2003)	3
NTRK1	1	EGFR	5	affinity chromatography technology	Emdal KB (2015)	1
MED4	2	TBK1	1	bioid	Lambert JP (2015)	1
GSK3B	1	XIAP	0	affinity chromatography technology	Sun M (2009)	1
NINL	1	TNIP1	1	bioid	Gupta GD (2015)	1
SASS6	1	SSX2IP	0	bioid	Gupta GD (2015)	1
TRAF3	1	IFIT3	1	affinity chromatography technology	Liu XY (2011)	1
TBKBP1	2	IKBKE	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li S (2011), Ryzhakov G (2007), Ryzhakov G (2007)	3
REL	5	RELA	1	affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Hansen SK (1994), Hansen SK (1994), Liss AS (2002), Liss AS (2002), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	8
XPO1	8	NFKB2	3	affinity chromatography technology	Kirli K (2015)	1
MED4	2	OFD1	3	bioid	Lambert JP (2015)	1
TRAF5	1	TRAF3	1	affinity chromatography technology, fluorescent resonance energy transfe, imaging technique	Li S (2011), He L (2004), Chen TC (2014)	3
TRIM10	3	TBK1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NFKB1	2	HIF1AN	0	affinity chromatography technology, two hybrid, affinity chromatography technology	Cockman ME (2006), Cockman ME (2006), Rodriguez J (2016)	3
RNF11	0	TNFAIP3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Shembade N (2009), Pranski EL (2012), Kelly C (2012), Colland F (2004)	4
TBK1	1	IRF7	2	pull down	Ikeda F (2007)	1
NEDD4	2	SYK	3	pull down	Persaud A (2009)	1
IKBKG	0	SSX2IP	0	two hybrid	Wang J (2011)	1
SYK	3	TRAF3	1	affinity chromatography technology	Lin YC (2013)	1
EGFR	5	APP	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
OPTN	1	TNIP1	1	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Wang J (2011), Rolland T (2014), Yu H (2011), Huttlin EL (2017)	4
BTRC	1	NEDD4	2	affinity chromatography technology, affinity chromatography technology	Liu J (2014), Liu J (2014)	2
REL	5	EGLN3	0	two hybrid, affinity chromatography technology	Rolland T (2014), Rodriguez J (2016)	2
TRAIP	0	TRAF3	1	affinity chromatography technology, affinity chromatography technology	Besse A (2007), Zhang M (2012)	2
EGLN3	0	NCOA2	2	affinity chromatography technology	Rodriguez J (2016)	1
TRAF3	1	TMEM173	0	affinity chromatography technology, affinity chromatography technology	Chen X (2014), Yao X (2016)	2
NTRK1	1	PBXIP1	1	affinity chromatography technology	Emdal KB (2015)	1
TANK	1	IRF3	4	affinity chromatography technology	Gatot JS (2007)	1
TRAF1	0	3324	0	affinity chromatography technology	Greenfeld H (2015)	1
XPO1	8	IRF3	4	affinity chromatography technology	Kirli K (2015)	1
SSX2IP	0	TBK1	1	bioid	Gupta GD (2015)	1
TBKBP1	2	AGO2	10	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
IKBKG	0	3324	0	affinity chromatography technology	Bouwmeester T (2004)	1
CEP128	1	MIB2	7	bioid	Gupta GD (2015)	1
TRIM14	1	CDC37	0	bioid	Tan P (2017)	1
CEP152	2	TBK1	1	bioid	Gupta GD (2015)	1
TOMM70	1	TBK1	1	affinity chromatography technology	Liu XY (2010)	1
NEDD4	2	SRC	2	affinity chromatography technology, pull down, enzymatic study	Persaud A (2014), Persaud A (2014), Persaud A (2014)	3
XPO1	8	NFKBIA	0	affinity chromatography technology	Kirli K (2015)	1
TBK1	1	3324	0	affinity chromatography technology	Bouwmeester T (2004)	1
TBK1	1	CTNNBL1	1	affinity chromatography technology	Richter B (2016)	1
MAVS	1	TRAF2	1	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li S (2011), Xu LG (2005), Yu H (2011), Minassian A (2015), Khan M (2016), Fang R (2017), Fang R (2017)	7
SYK	3	NCK1	0	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
NTRK1	1	PPP6R1	4	affinity chromatography technology	Emdal KB (2015)	1
CYLD	2	YWHAE	0	affinity chromatography technology	Elliott PR (2016)	1
BBOX1	0	AZI2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TRAF3	1	SMURF1	4	genetic interference	Li S (2010)	1
SRC	2	ESR1	0	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, imaging technique, imaging technique, imaging technique, pull down, imaging technique, imaging technique, affinity chromatography technology, two hybrid	Migliaccio A (2000), Teo AK (2001), Slentz-Kesler K (2000), Bourdoncle A (2005), Jaber BM (2004), Jaber BM (2004), Ku TK (2007), Cabodi S (2004), Monroe DG (2003), Hitosugi T (2007), Zwart W (2007), Zwart W (2007), Zwart W (2007), Yoshimaru T (2013), Yoshimaru T (2013), Zhang H (2006), Zhang H (2006), Zhang H (2006), Endler A (2012), Endler A (2012)	20
TLR3	2	TRAF6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang M (2011), Jiang Z (2003), Jiang Z (2003), Cusson-Hermance N (2005), Zinngrebe J (2016)	5
TRIM27	2	TRIM23	3	two hybrid, two hybrid	Reymond A (2001), Woodsmith J (2012)	2
TBK1	1	TANK	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Bouwmeester T (2004), Pomerantz JL (1999), Gatot JS (2007), Li S (2011), Li S (2011), Shen RR (2012), Ryzhakov G (2007), Wang J (2011), Seo S (2013), Saul VV (2014), Richter B (2016), Shostak K (2014)	12
PLK1	0	TANK	1	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Zhang W (2010), Zhang W (2010), Zhang W (2010), Wang J (2011), Wang J (2011)	5
NTRK1	1	TRAF6	0	affinity chromatography technology, enzymatic study, affinity chromatography technology	Jadhav T (2008), Geetha T (2005), Zheng C (2015)	3
TICAM1	3	TLR4	5	affinity chromatography technology, affinity chromatography technology	Piao W (2009), Hu YH (2015)	2
MED4	2	CTNNBL1	1	two hybrid	Rolland T (2014)	1
IKBKE	2	RELA	1	enzymatic study	Buss H (2004)	1
TRAIP	0	TRAF6	0	affinity chromatography technology	Besse A (2007)	1
RELA	1	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology	Spencer E (1999), Spencer E (1999), Coyaud E (2015), Coyaud E (2015), Huttlin EL (2017)	5
SOCS3	0	TBK1	1	pull down, pull down, affinity chromatography technology	Liu D (2015), Liu D (2015), Liu D (2015)	3
TBK1	1	PPP6R1	4	affinity chromatography technology	Bouwmeester T (2004)	1
STX12	2	OPTN	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FMR1	1	NCK1	0	biochemical	Wan C (2015)	1
TBK1	1	TRIM14	1	affinity chromatography technology	Zhou Z (2014)	1
DDX58	3	MAVS	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gack MU (2010), Gack MU (2009), Nistal-Villan E (2010), Kawai T (2005), Li S (2011), Li S (2011), Inn KS (2011), Arnaud N (2011), Maharaj NP (2011), Meylan E (2005), Xu LG (2005), Cui J (2010), Wei C (2010), Zhang H (2015), Tan P (2017)	15
LATS2	1	TBKBP1	2	bioid	Couzens AL (2013)	1
SMURF1	4	APP	1	pull down	Olah J (2011)	1
SQSTM1	0	NTRK1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wooten MW (2001), Geetha T (2003), Jadhav T (2008), Wooten MW (2008), Wooten MW (2008), Zheng C (2015)	6
XPO1	8	PPP6C	7	affinity chromatography technology	Kirli K (2015)	1
NFKBIA	0	RELA	1	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen Lf (2001), Kiernan R (2003), Kiernan R (2003), Spencer E (1999), Spencer E (1999), Hay DC (2001), Hansen SK (1994), Malek S (1998), Cohen L (1998), Robert I (2009), Sasaki CY (2005), Wu BY (1995), Fagan-Garcia K (2011), Livolsi A (2001), Van Antwerp DJ (1996), Van Antwerp DJ (1996), Krappmann D (1996), Chen Z (1995), Bottero V (2001), Wang H (2010), DiDonato J (1996), Carvalho G (2010), Carvalho G (2010), Suzuki H (1999), Tsuchiya Y (2010), Da Silva-Ferrada E (2011), Pringle LM (2011), Pringle LM (2011), Pringle LM (2011), DiDonato J (1996), Ryo A (2003), Ryo A (2003), Inan MS (2000), Burstein E (2005), Chu ZL (1996), Chu ZL (1996), Starokadomskyy P (2013), Wang J (2011), Arenzana-Seisdedos F (1995), Arenzana-Seisdedos F (1997), Wood KM (1998), Cockman ME (2006), Cockman ME (2006), Li JM (2013), Rodriguez MS (1999), Huttlin EL (2015), Hein MY (2015), Taura M (2015), Kim MY (2015), Schweitzer K (2016), Schweitzer K (2016), Hochrainer K (2015), Jiang GM (2017), Huttlin EL (2017), Kumar S (2012), Kumar S (2012)	56
PLK1	0	PPP6R2	3	affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Svendsen JM (2009), Couzens AL (2013), Couzens AL (2013), Huttlin EL (2015), Huttlin EL (2017)	5
TNFAIP3	3	TNIP1	1	affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid	Heyninck K (1999), Heyninck K (1999), Bohgaki M (2008), Klinkenberg M (2001), Heyninck K (2003), Wang J (2011), Rodriguez MS (2014), Rolland T (2014)	8
TRAF6	0	TRAF5	1	two hybrid, two hybrid, two hybrid, pull down	Woodsmith J (2012), Rolland T (2014), Yu H (2011), Middleton AJ (2017)	4
TBK1	1	MTPAP	2	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
CEP128	1	CEP135	2	affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
TBK1	1	SQSTM1	0	enzymatic study, enzymatic study	Matsumoto G (2015), Richter B (2016)	2
EGFR	5	TRAF2	1	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2008), Puliyappadamba VT (2013), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
SSX2IP	0	TXLNG	1	bioid	Gupta GD (2015)	1
SSX2IP	0	TNIP1	1	bioid	Gupta GD (2015)	1
MCM2	3	APP	1	pull down	Olah J (2011)	1
STX12	2	TXLNA	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGLN3	0	AZI2	1	affinity chromatography technology	Rodriguez J (2016)	1
AKT1	1	NFKBIA	0	affinity chromatography technology	Koul D (2001)	1
TRIM14	1	TAX1BP1	3	two hybrid	Tan P (2017)	1
ODF2	1	CYLD	2	bioid	Gupta GD (2015)	1
NINL	1	OFD1	3	bioid	Gupta GD (2015)	1
CEP128	1	TANK	1	bioid	Gupta GD (2015)	1
CNTROB	6	TBK1	1	bioid	Gupta GD (2015)	1
MCM2	3	TBKBP1	2	affinity chromatography technology	Drissi R (2015)	1
NTRK1	1	ANKRD28	1	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	XPO1	8	affinity chromatography technology	Foerster S (2013)	1
IKBKG	0	TNFAIP3	3	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Zhang SQ (2000), Zhang SQ (2000), Skaug B (2011), Skaug B (2011), Klinkenberg M (2001), Verhelst K (2012), Verhelst K (2012), Wang J (2011), Zilberman-Rudenko J (2016)	9
BTRC	1	SSX2IP	0	bioid	Coyaud E (2015)	1
TBKBP1	2	RB1CC1	9	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
XPO1	8	APBA3	2	affinity chromatography technology	Kirli K (2015)	1
TAX1BP1	3	IKBKE	2	affinity chromatography technology	Gao L (2011)	1
SOCS3	0	TRAF6	0	affinity chromatography technology, affinity chromatography technology	Frobose H (2006), Zhou X (2015)	2
TRAF1	0	TRAF3	1	affinity chromatography technology, affinity chromatography technology	Pullen SS (1998), Greenfeld H (2015)	2
CEP128	1	CEP44	2	bioid	Gupta GD (2015)	1
OPTN	1	TBK1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, imaging technique, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Li S (2011), Li S (2011), Li S (2011), Mankouri J (2010), Mankouri J (2010), Mankouri J (2010), Morton S (2008), Morton S (2008), Freischmidt A (2015), Freischmidt A (2015), Heo JM (2015), Heo JM (2015), Genin P (2015), Genin P (2015), Richter B (2016), Richter B (2016), Richter B (2016), Pourcelot M (2016)	18
TNF	0	TBK1	1	affinity chromatography technology	Kuai J (2004)	1
NTRK1	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rao R (2010), Taipale M (2012), Emdal KB (2015)	3
TBK1	1	SRC	2	affinity chromatography technology	Johnsen IB (2009)	1
CYLD	2	HSP90AA1	7	affinity chromatography technology	Elliott PR (2016)	1
TAX1BP1	3	OPTN	1	affinity chromatography technology, affinity chromatography technology	Journo C (2009), Journo C (2009)	2
BBOX1	0	TXLNA	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
LATS2	1	CYLD	2	bioid	Couzens AL (2013)	1
TLR4	5	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang M (2011), Floreani NA (2010), Floreani NA (2010)	3
ANKRD28	1	PPP6R2	3	affinity chromatography technology, bioid, affinity chromatography technology, bioid, affinity chromatography technology	Couzens AL (2013), Couzens AL (2013), Couzens AL (2013), Couzens AL (2013), Huttlin EL (2017)	5
IKBKE	2	YAP1	0	affinity chromatography technology	Zhang Q (2017)	1
SOCS3	0	NFKBIA	0	affinity chromatography technology, affinity chromatography technology	Nair S (2011), Nair S (2011)	2
USP2	0	TRIM23	3	two hybrid	Hayes SD (2012)	1
ATG9A	5	HERPUD1	2	affinity chromatography technology	Huttlin EL (2017)	1
SRC	2	IKBKG	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Funakoshi-Tago M (2005), Funakoshi-Tago M (2005), Lee SH (2012)	3
NINL	1	TXLNA	3	bioid	Gupta GD (2015)	1
TNIP1	1	IKBKE	2	affinity chromatography technology, affinity chromatography technology	Gao L (2011), Gao L (2011)	2
TRIM23	3	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Sparrer KMJ (2017), Sparrer KMJ (2017)	2
NEDD4	2	NTRK1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, affinity chromatography technology	Arevalo JC (2006), Arevalo JC (2006), Arevalo JC (2006), Georgieva MV (2011), Georgieva MV (2011), Persaud A (2009), Persaud A (2009), Emdal KB (2015)	8
CCDC8	1	SRC	2	affinity chromatography technology	Hanson D (2014)	1
TICAM1	3	TRAF2	1	two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, two hybrid	Sasai M (2010), Sasai M (2010), Sasai M (2010), Jiang Z (2004), Takaki H (2009)	5
CCDC8	1	YWHAE	0	affinity chromatography technology	Hanson D (2014)	1
TBK1	1	TBKBP1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Li S (2011), Li S (2011), Ryzhakov G (2007), Ryzhakov G (2007), Ryzhakov G (2007), Seo S (2013), Richter B (2016)	8
TLR9	2	SRC	2	affinity chromatography technology	Yang M (2011)	1
TRAF3	1	TBK1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kayagaki N (2007), Mankouri J (2010), Mankouri J (2010), Tzieply N (2012), Wang Y (2012), Ng MH (2011), Charoenthongtrakul S (2013), van Zuylen WJ (2012), van Zuylen WJ (2012), Karim R (2013), Chen X (2014), Peng Y (2014), Wang S (2013), Zhou Y (2016), Cai B (2017), Fang R (2017), Fang R (2017)	17
CEP135	2	TNIP1	1	bioid	Gupta GD (2015)	1
CEP128	1	LATS2	1	bioid	Gupta GD (2015)	1
HERC2	9	TBK1	1	affinity chromatography technology	Al-Hakim AK (2012)	1
TMEM173	0	IRF3	4	affinity chromatography technology, affinity chromatography technology	Chen X (2014), Liu S (2015)	2
TBK1	1	LETM1	6	affinity chromatography technology	Li S (2011)	1
IKBKE	2	CYLD	2	affinity chromatography technology, affinity chromatography technology	Friedman CS (2008), Zhou AY (2013)	2
EGLN3	0	SQSTM1	0	affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology	Rantanen K (2013), Rantanen K (2013), Rantanen K (2013), Rodriguez J (2016)	4
MIB2	7	IKBKG	0	affinity chromatography technology	Stempin CC (2011)	1
TRAF1	0	TRAF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Takeuchi M (1996), Li S (2011), Li S (2011), Fries KL (1999), He L (2004), Zheng C (2010), Zheng C (2010), Relaix F (1998), Relaix F (1998), Jang HD (2001), Fotin-Mleczek M (2004), Pullen SS (1998), Wicovsky A (2009), Rothe M (1994), Rothe M (1994), Chen TC (2014), Greenfeld H (2015), Huttlin EL (2017)	19
DYRK2	1	RB1CC1	9	affinity chromatography technology	Varjosalo M (2013)	1
AKT1	1	APP	1	pull down	Olah J (2011)	1
TRAF3	1	SRC	2	affinity chromatography technology, affinity chromatography technology	Wong BR (1999), Johnsen IB (2009)	2
IKBKG	0	RELA	1	enzymatic study	Dan HC (2008)	1
CUL1	7	AGO2	10	affinity chromatography technology	Bennett EJ (2010)	1
CNTROB	6	OFD1	3	bioid	Gupta GD (2015)	1
STIL	3	TBK1	1	bioid	Gupta GD (2015)	1
CEP63	2	OFD1	3	bioid, bioid, bioid	Firat-Karalar EN (2014), Gupta GD (2015), Gupta GD (2015)	3
CUL1	7	3324	0	affinity chromatography technology	Bennett EJ (2010)	1
IKBKG	0	TANK	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Chariot A (2002), Chariot A (2002), Chariot A (2002), Zhang W (2010), Zhang W (2010), Zhao T (2007), Wang J (2011), Wang W (2015), Huttlin EL (2017)	9
TANK	1	PBXIP1	1	affinity chromatography technology	Shostak K (2014)	1
XIAP	0	IRF3	4	affinity chromatography technology	Nakhaei P (2012)	1
MAP1LC3B	1	TBK1	1	pull down	Wild P (2011)	1
OFD1	3	TBK1	1	bioid	Gupta GD (2015)	1
LATS2	1	SSX2IP	0	bioid	Couzens AL (2013)	1
SOCS3	0	NFKB1	2	affinity chromatography technology, affinity chromatography technology	Nair S (2011), Nair S (2011)	2
TRAF5	1	TRIM27	2	two hybrid	Woodsmith J (2012)	1
TLR3	2	IKBKG	0	affinity chromatography technology	Zinngrebe J (2016)	1
WHRN	1	TBK1	1	affinity chromatography technology	Boldt K (2016)	1
XPO1	8	GSK3B	1	affinity chromatography technology	Kirli K (2015)	1
CEP128	1	PLK1	0	bioid	Gupta GD (2015)	1
TBK1	1	BTRC	1	affinity chromatography technology	Bouwmeester T (2004)	1
AKT1	1	YWHAE	0	affinity chromatography technology	Klein JB (2005)	1
TRAF6	0	AKT1	1	enzymatic study, affinity chromatography technology, affinity chromatography technology	Yang WL (2009), Mitra S (2011), Mitra S (2011)	3
LATS2	1	TBK1	1	bioid	Couzens AL (2013)	1
MCM2	3	XPO1	8	affinity chromatography technology	Drissi R (2015)	1
NEDD4	2	PLK1	0	pull down, enzymatic study	Persaud A (2009), Li Z (2014)	2
EXOC2	5	TBK1	1	affinity chromatography technology	Simicek M (2013)	1
IRF7	2	MAVS	1	affinity chromatography technology	Xu LG (2005)	1
TBK1	1	TXLNA	3	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Li S (2011), Li S (2011), Li S (2011), Li S (2011), Huttlin EL (2017)	5
TRAF5	1	SMURF1	4	genetic interference	Li S (2010)	1
OPTN	1	SQSTM1	0	affinity chromatography technology, pull down	Liu Z (2014), Liu Z (2014)	2
TNFAIP3	3	SRC	2	affinity chromatography technology	Huttlin EL (2017)	1
NINL	1	SASS6	1	bioid	Gupta GD (2015)	1
SMURF1	4	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Cui Y (2011), Zhang Y (2017), Zhang Y (2017), Zhang Y (2017), Zhang Y (2017)	5
NCK1	0	EGFR	5	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay	Tang J (1997), Li W (1992), Braverman LE (1999), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	6
ESR1	0	RELA	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Olivier S (2006), Nettles KW (2008), Nettles KW (2008), Rubio MF (2006), Rubio MF (2006)	5
CEP128	1	TRIM9	3	bioid	Gupta GD (2015)	1
DDX58	3	TBK1	1	affinity chromatography technology	Oshiumi H (2013)	1
TRAF6	0	IRF7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kawai T (2004), Young JA (2011), Hu Y (2011), Ning S (2008), Ning S (2008), Naiki Y (2015), Naiki Y (2015)	7
CUL1	7	AKT1	1	affinity chromatography technology	Reitsma JM (2017)	1
CEP135	2	SSX2IP	0	bioid, affinity chromatography technology	Gupta GD (2015), Hein MY (2015)	2
EGLN3	0	CCDC8	1	affinity chromatography technology	Rodriguez J (2016)	1
YAP1	0	YWHAE	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Couzens AL (2013), Hauri S (2013), Enzo E (2015)	3
TXLNB	0	TBK1	1	affinity chromatography technology	Huttlin EL (2017)	1
ESR1	0	TBK1	1	affinity chromatography technology	Wang C (2015)	1
EGFR	5	ESR1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hitosugi T (2007), Hitosugi T (2007), Yao Z (2017)	3
RNF11	0	OPTN	1	two hybrid	Colland F (2004)	1
MAVS	1	PPP6C	7	affinity chromatography technology, imaging technique	Tan P (2017), Tan P (2017)	2
IKBKG	0	PBXIP1	1	affinity chromatography technology	Shostak K (2014)	1
TBK1	1	TMEM173	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsuchida T (2010), Li S (2011), Zhang J (2012), Zhang J (2012), Chen X (2014), Ni G (2017), Zhang Q (2017)	7
CEP44	2	OFD1	3	bioid	Gupta GD (2015)	1
TOMM70	1	TRAF6	0	affinity chromatography technology	Liu XY (2010)	1
TBKBP1	2	APBA3	2	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
HERC2	9	MAVS	1	affinity chromatography technology	Galligan JT (2015)	1
EGLN3	0	TXLNA	3	affinity chromatography technology	Rodriguez J (2016)	1
CALCOCO2	0	AZI2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li S (2011), Li S (2011), Huttlin EL (2017)	3
TRAF2	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Huttlin EL (2017)	2
IRF3	4	TRAF3	1	affinity chromatography technology, affinity chromatography technology	Ng MH (2011), Gu L (2017)	2
XPO1	8	REL	5	affinity chromatography technology	Kirli K (2015)	1
PPP6C	7	ANKRD28	1	affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zeng K (2010), Couzens AL (2013), Couzens AL (2013), Couzens AL (2013), St-Denis N (2016), Yadav L (2017)	6
DYRK2	1	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
IKBKG	0	BTRC	1	affinity chromatography technology	Orel L (2010)	1
REL	5	ATG9A	5	two hybrid	Rolland T (2014)	1
CEP63	2	MED4	2	bioid	Gupta GD (2015)	1
TNIP1	1	TXLNA	3	two hybrid	Rolland T (2014)	1
TBK1	1	RNF128	1	affinity chromatography technology, pull down, enzymatic study	Song G (2016), Song G (2016), Song G (2016)	3
CUL1	7	IRF3	4	affinity chromatography technology	Bibeau-Poirier A (2006)	1
SYK	3	APP	1	pull down	Olah J (2011)	1
EGFR	5	TRIM23	3	affinity chromatography technology	Yao Z (2017)	1
HSP90AA1	7	SRC	2	affinity chromatography technology, affinity chromatography technology	Hutchison KA (1992), Tsutsumi S (2012)	2
AZI2	1	MTPAP	2	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
MAVS	1	TRAF6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li S (2011), Wang Y (2012), Xu LG (2005), Wang P (2013), Wang P (2013), Shi Z (2015), Shi Z (2015), Minassian A (2015), Khan M (2016), Fang R (2017), Fang R (2017)	11
MAVS	1	MIB2	7	affinity chromatography technology	Ye JS (2014)	1
TANK	1	CEP63	2	two hybrid, bioid	Rolland T (2014), Gupta GD (2015)	2
XPO1	8	TRIM26	1	affinity chromatography technology	Kirli K (2015)	1
TRIM23	3	TBK1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Sparrer KMJ (2017), Sparrer KMJ (2017), Sparrer KMJ (2017), Sparrer KMJ (2017)	4
CALCOCO2	0	MAVS	1	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
TBK1	1	CDC42BPG	3	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
TANK	1	TRAF3	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, affinity chromatography technology	Bouwmeester T (2004), Rothe M (1996), Gatot JS (2007), Li S (2011), Li C (2003), Li C (2002), Li C (2002), Ng MH (2011)	8
BBOX1	0	CALCOCO2	0	affinity chromatography technology	Huttlin EL (2015)	1
APP	1	APBA3	2	affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology	Biederer T (2002), Biederer T (2002), Tanahashi H (1999), Tanahashi H (1999), Huttlin EL (2017)	5
MED4	2	SSX2IP	0	bioid	Lambert JP (2015)	1
AZI2	1	TBKBP1	2	affinity chromatography technology, affinity chromatography technology	Ryzhakov G (2007), Ryzhakov G (2007)	2
AZI2	1	APBA3	2	affinity chromatography technology, pull down, affinity chromatography technology	Li S (2011), Li S (2011), Huttlin EL (2017)	3
TRAF6	0	SMURF1	4	genetic interference	Li S (2010)	1
SOCS3	0	APP	1	pull down	Olah J (2011)	1
NTRK1	1	FMR1	1	affinity chromatography technology	Emdal KB (2015)	1
PLK1	0	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
HIF1AN	0	PPP6C	7	affinity chromatography technology	Rodriguez J (2016)	1
NTRK1	1	FXR2	2	affinity chromatography technology	Emdal KB (2015)	1
GSK3B	1	BTRC	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Kitagawa M (1999), Gao C (2014), Gao C (2014), Gao C (2014)	4
TBK1	1	MBP	0	enzymatic study	Ikeda F (2007)	1
TICAM1	3	SYK	3	affinity chromatography technology	Lin YC (2013)	1
NCOA2	2	TBK1	1	affinity chromatography technology, biochemical, affinity chromatography technology	Jung SY (2005), Jung SY (2005), Jung SY (2005)	3
HNRNPL	3	STX3	3	affinity chromatography technology	Fei T (2017)	1
TBK1	1	AGO2	10	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
TRAF3	1	TAX1BP1	3	affinity chromatography technology	Gao L (2011)	1
CDC37	0	IFIT3	1	two hybrid, pull down, affinity chromatography technology	Soler-Lopez M (2011), Soler-Lopez M (2011), Soler-Lopez M (2011)	3
HNRNPL	3	TBKBP1	2	affinity chromatography technology	Fei T (2017)	1
LATS2	1	SRC	2	affinity chromatography technology	Si Y (2017)	1
SSX2IP	0	FMR1	1	bioid	Gupta GD (2015)	1
NFKBIA	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kawakami T (2001), Read MA (2000), Suzuki H (1999), Surjit M (2012), Furukawa M (2000), Furukawa M (2000)	6
EGLN3	0	NFKBIA	0	affinity chromatography technology	Rodriguez J (2016)	1
MAVS	1	TAX1BP1	3	affinity chromatography technology	Choi YB (2017)	1
TRIM14	1	MAVS	1	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique	Zhou Z (2014), Zhou Z (2014), Zhou Z (2014), Tan P (2017), Tan P (2017)	5
MCM2	3	HSP90AA1	7	affinity chromatography technology	Drissi R (2015)	1
TRAF3IP2	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Wu L (2014), Boisson B (2013)	2
CEP135	2	OFD1	3	bioid, affinity chromatography technology	Gupta GD (2015), Hein MY (2015)	2
EGFR	5	CDC37	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lavictoire SJ (2003), Foerster S (2013), Li J (2013), Li J (2013)	4
TXLNG	1	TXLNB	0	affinity chromatography technology, affinity chromatography technology	Li S (2011), Huttlin EL (2017)	2
MED4	2	TAX1BP1	3	affinity chromatography technology	Lambert JP (2015)	1
HSP90AA1	7	TRIM10	3	affinity chromatography technology	Taipale M (2012)	1
CEP44	2	TXLNG	1	bioid	Gupta GD (2015)	1
STX3	3	TBK1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TRAF2	1	IKBKG	0	affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tang ED (2003), Poyet JL (2000), Shen RR (2012), Shen RR (2012), Bal E (2017), Bal E (2017)	6
CEP44	2	PPP6R1	4	bioid	Gupta GD (2015)	1
EGLN3	0	PPP6R1	4	affinity chromatography technology	Rodriguez J (2016)	1
BTRC	1	YWHAE	0	affinity chromatography technology	Coyaud E (2015)	1
TRAF2	1	FXR2	2	two hybrid	Rual JF (2005)	1
NTRK1	1	TBK1	1	affinity chromatography technology	Emdal KB (2015)	1
OFD1	3	MIB1	5	affinity chromatography technology	Hein MY (2015)	1
AZI2	1	IKBKE	2	affinity chromatography technology, affinity chromatography technology	Li S (2011), Ryzhakov G (2007)	2
IKBKG	0	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Martin P (2006), Zotti T (2014)	2
LATS2	1	YAP1	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, fluorescent resonance energy transfe, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, fluorescent resonance energy transfe, enzymatic study	Ikeda M (2009), Zhang J (2008), Zhang J (2008), Vigneron AM (2010), Vigneron AM (2010), Bao Y (2009), Kawahara M (2008), Paramasivam M (2011), Aylon Y (2010), Oka T (2008), Yu FX (2012), Mo XL (2015), Rashidian J (2015), Kim M (2016), Enzo E (2015), Si Y (2017), Ivanov AA (2017), Zhu C (2018)	18
IRF3	4	TRAF6	0	affinity chromatography technology	Liu S (2015)	1
DDX58	3	IFIT3	1	affinity chromatography technology	Liu XY (2011)	1
TBK1	1	CALCOCO2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Thurston TL (2009), Li S (2011), Li S (2011), Li S (2011), Li S (2011), Huttlin EL (2017)	6
TRAIP	0	TRAF2	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Lee SY (1997), Lee SY (1997), Besse A (2007), Park ES (2015)	4
NTRK1	1	LETM1	6	affinity chromatography technology	Emdal KB (2015)	1
TANK	1	APBA3	2	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
YWHAE	0	XPO1	8	biochemical	Kristensen AR (2012)	1
PELI1	1	TRAF6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jiang Z (2003), Jiang Z (2003), Choi KC (2006), Jensen LE (2003)	4
MAVS	1	TOMM70	1	affinity chromatography technology, affinity chromatography technology	Liu XY (2010), Liu XY (2010)	2
CEP152	2	TXLNA	3	bioid	Gupta GD (2015)	1
ODF2	1	CEP44	2	bioid	Gupta GD (2015)	1
EGLN3	0	SSX2IP	0	affinity chromatography technology	Rodriguez J (2016)	1
EGFR	5	SYK	3	unspecified method	Jones RB (2006)	1
IKBKG	0	TNIP1	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Ashida H (2010), Wagner S (2008), Wang J (2011)	3
SSX2IP	0	TRIM26	1	bioid	Gupta GD (2015)	1
NEDD4	2	AKT1	1	enzymatic study, enzymatic study, affinity chromatography technology	Persaud A (2009), Fan CD (2013), Fan CD (2013)	3
HSP90AA1	7	CDC37	0	x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Roe SM (2004), Silverstein AM (1998), Mollapour M (2010), Basso AD (2002), Tsutsumi S (2012), De Nardo D (2005), Sarkar S (2012), Gano JJ (2010), Taipale M (2012), Skarra DV (2011), Zhang H (2004), Taipale M (2014), Taipale M (2014), Mollapour M (2014), Hein MY (2015), Hein MY (2015), Li J (2013), Woodford MR (2016), Shao J (2003), Scholz GM (2001), Sun L (2012), Sun L (2012), Woodford MR (2016), Synoradzki K (2015)	24
HIF1AN	0	APBA3	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Huttlin EL (2017), Sakamoto T (2009), Sakamoto T (2009), Sakamoto T (2009), Rodriguez J (2016)	5
WHRN	1	TBKBP1	2	affinity chromatography technology	Boldt K (2016)	1
MCM2	3	HNRNPL	3	affinity chromatography technology	Drissi R (2015)	1
RNF11	0	TAX1BP1	3	affinity chromatography technology, two hybrid	Shembade N (2009), Colland F (2004)	2
TBKBP1	2	FXR2	2	affinity chromatography technology	Li S (2011)	1
TRAF2	1	CALCOCO2	0	two hybrid	Rual JF (2005)	1
HERPUD1	2	TBK1	1	affinity chromatography technology	Ge M (2017)	1
CEP128	1	SSX2IP	0	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
CALCOCO2	0	TAX1BP1	3	affinity chromatography technology, two hybrid	Morriswood B (2007), Morriswood B (2007)	2
HIF1AN	0	TXLNG	1	affinity chromatography technology	Huttlin EL (2017)	1
TRAIP	0	TRAF5	1	affinity chromatography technology	Besse A (2007)	1
OPTN	1	TRAF3	1	affinity chromatography technology, affinity chromatography technology	Mankouri J (2010), Mankouri J (2010)	2
EGLN3	0	HMMR	1	affinity chromatography technology	Rodriguez J (2016)	1
TBK1	1	ATG9A	5	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
NTRK1	1	CDC37	0	affinity chromatography technology, affinity chromatography technology	Rao R (2010), Emdal KB (2015)	2
AGO2	10	TNF	0	affinity chromatography technology	El Gazzar M (2011)	1
HNRNPL	3	CDC42BPG	3	affinity chromatography technology	Fei T (2017)	1
IKBKG	0	EGLN3	0	affinity chromatography technology, affinity chromatography technology, pull down	Fu J (2013), Fu J (2013), Fu J (2013)	3
CYLD	2	HNRNPL	3	affinity chromatography technology	Elliott PR (2016)	1
XPO1	8	TNIP1	1	affinity chromatography technology	Kirli K (2015)	1
EGLN3	0	RELA	1	affinity chromatography technology	Rodriguez J (2016)	1
AKT1	1	TBK1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Joung SM (2011), Joung SM (2011), Joung SM (2011)	3
SASS6	1	MED4	2	bioid	Gupta GD (2015)	1
CALCOCO2	0	FMR1	1	affinity chromatography technology	Li S (2011)	1
CCDC8	1	TBK1	1	affinity chromatography technology	Hanson D (2014)	1
MIB2	7	TBK1	1	enzymatic study	Li S (2011)	1
NEDD4	2	CUL1	7	affinity chromatography technology	Liu J (2014)	1
CEP63	2	CEP152	2	bioid, bioid, bioid, bioid	Firat-Karalar EN (2014), Firat-Karalar EN (2014), Gupta GD (2015), Gupta GD (2015)	4
TNFAIP3	3	TBK1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Gao L (2011), Saitoh T (2005)	3
MCM2	3	YWHAE	0	affinity chromatography technology	Drissi R (2015)	1
FXR2	2	TRIM23	3	two hybrid	Venkatesan K (2009)	1
ESR1	0	RBBP5	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mo R (2006), Mo R (2006), Shi L (2011), Shi L (2011)	4
XPO1	8	SSX2IP	0	affinity chromatography technology	Kirli K (2015)	1
NTRK1	1	TAX1BP1	3	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	PPP6R1	4	affinity chromatography technology	Foerster S (2013)	1
CCDC8	1	MCM2	3	affinity chromatography technology	Hanson D (2014)	1
MAP1LC3B	1	OPTN	1	imaging technique, unspecified method, pull down, x-ray crystallography, affinity chromatography technology, pull down	Wild P (2011), Wild P (2011), Rogov VV (2013), Rogov VV (2013), Rogov VV (2013), Wild P (2011)	6
EGFR	5	TBK1	1	affinity chromatography technology	Tong J (2014)	1
APBA3	2	TBK1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NEDD4	2	EGFR	5	enzymatic study, pull down	Persaud A (2009), Persaud A (2009)	2
TBK1	1	RNF11	0	affinity chromatography technology, affinity chromatography technology	Charoenthongtrakul S (2013), Charoenthongtrakul S (2013)	2
CEP128	1	ODF2	1	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
DYRK2	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Maddika S (2009), Taipale M (2012)	2
TICAM1	3	TNFAIP3	3	affinity chromatography technology	Wang YY (2004)	1
HIF1AN	0	NFKB2	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Rodriguez J (2016)	2
DTX4	7	NLRP4	5	affinity chromatography technology	Cui J (2012)	1
TICAM1	3	TLR3	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jiang Z (2004), Hu YH (2015), Zinngrebe J (2016)	3
LATS2	1	CNTROB	6	bioid	Couzens AL (2013)	1
CEP135	2	CYLD	2	bioid	Gupta GD (2015)	1
CYLD	2	PLK1	0	affinity chromatography technology, affinity chromatography technology	Stegmeier F (2007), Stegmeier F (2007)	2
NINL	1	PLK1	0	affinity chromatography technology, two hybrid, enzymatic study, bioid	Casenghi M (2003), Casenghi M (2003), Casenghi M (2003), Gupta GD (2015)	4
TBK1	1	ANKRD28	1	affinity chromatography technology, bioid	Bouwmeester T (2004), Couzens AL (2013)	2
CEP135	2	MIB1	5	affinity chromatography technology	Hein MY (2015)	1
TRAF1	0	TRAF6	0	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Wang J (2011), Rolland T (2014), Yu H (2011), Huttlin EL (2017)	4
BTRC	1	NFKBIA	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, enzymatic study, enzymatic study, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, bioid, enzymatic study, protein complementation assay	Suzuki H (2000), Spencer E (1999), Spencer E (1999), Spencer E (1999), Suzuki H (1999), Suzuki H (1999), Kroll M (1999), Kroll M (1999), Yaron A (1998), Choi YS (2010), Banerjee S (2010), Banerjee S (2010), Banerjee S (2010), Da Silva-Ferrada E (2011), Tsuchiya Y (2010), Tsuchiya Y (2010), Keutgens A (2010), Winston JT (1999), Winston JT (1999), Winston JT (1999), Winston JT (1999), Surjit M (2012), Busino L (2012), Evrard-Todeschi N (2008), Furukawa M (2000), Kovacev J (2014), Chong RA (2014), Chong RA (2014), Shi M (2014), Shirane M (1999), Read MA (2000), Tan M (2010), Coyaud E (2015), Coyaud E (2015), Wu K (2016), Villalobos V (2010)	36
CCDC8	1	RB1CC1	9	affinity chromatography technology	Hanson D (2014)	1
CEP44	2	TNIP1	1	bioid	Gupta GD (2015)	1
IKBKG	0	SCLT1	1	pull down	Fenner BJ (2010)	1
CCDC8	1	OFD1	3	affinity chromatography technology	Hanson D (2014)	1
TBKBP1	2	FMR1	1	affinity chromatography technology	Li S (2011)	1
SMURF1	4	MAVS	1	affinity chromatography technology	Wang Y (2012)	1
EGLN3	0	GSK3B	1	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	APBA3	2	affinity chromatography technology	Rodriguez J (2016)	1
IKBKE	2	XIAP	0	enzymatic study	Nakhaei P (2012)	1
EGLN3	0	TBKBP1	2	affinity chromatography technology	Rodriguez J (2016)	1
HIF1AN	0	RELA	1	affinity chromatography technology	Rodriguez J (2016)	1
IKBKE	2	IFIT3	1	affinity chromatography technology	Liu XY (2011)	1
FXR2	2	CALCOCO2	0	two hybrid	Rual JF (2005)	1
IRF3	4	TICAM1	3	affinity chromatography technology	Liu S (2015)	1
NTRK1	1	EXOC2	5	affinity chromatography technology	Emdal KB (2015)	1
NFKB2	3	IKBKG	0	affinity chromatography technology	Bouwmeester T (2004)	1
DDX58	3	TRIM14	1	affinity chromatography technology, imaging technique	Tan P (2017), Tan P (2017)	2
MAP1LC3B	1	TAX1BP1	3	pull down, two hybrid	Newman AC (2012), Tumbarello DA (2015)	2
GSK3B	1	IKBKG	0	imaging technique, enzymatic study, affinity chromatography technology, affinity chromatography technology	Chen TC (2014), Medunjanin S (2016), Medunjanin S (2016), Medunjanin S (2016)	4
MED4	2	ODF2	1	bioid, bioid	Lambert JP (2015), Gupta GD (2015)	2
CEP152	2	OFD1	3	bioid	Gupta GD (2015)	1
NEDD4	2	HNRNPL	3	pull down	Ingham RJ (2005)	1
TNFAIP3	3	TAX1BP1	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	De Valck D (1999), De Valck D (1999), Klinkenberg M (2001), Kelly C (2012), Huttlin EL (2017)	5
NINL	1	CYLD	2	bioid	Gupta GD (2015)	1
USP2	0	TBK1	1	affinity chromatography technology	Zhang L (2014)	1