PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
POLR2F	1	POLR2H	0	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
CIITA	4	TBP	0	affinity chromatography technology	Beaulieu YB (2016)	1
LSM4	1	GTF2B	1	biochemical	Havugimana PC (2012)	1
GTF2F2	0	CTDP1	2	affinity chromatography technology	Jeronimo C (2007)	1
BCL3	2	CTBP1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Keutgens A (2010), Keutgens A (2010), Choi HJ (2010), Choi HJ (2010), Choi HJ (2010), Choi HJ (2010)	6
ATF4	2	JUN	0	pull down, two hybrid, fluorescent resonance energy transfe, fluorescent resonance energy transfe, imaging technique	Hai T (1991), Bandyopadhyay S (2010), Reinke AW (2013), Reinke AW (2013), Chen TC (2014)	5
GTF2E1	1	TBP	0	pull down, biochemical, pull down	Scully R (1997), Scully R (1997), Maxon ME (1994)	3
GTF2B	1	PRPF18	6	biochemical	Wan C (2015)	1
DUSP6	2	283458	0	affinity chromatography technology	Li X (2016)	1
NR5A1	1	CREBBP	29	pull down	Ito M (2000)	1
JUN	0	KLF5	4	pull down, pull down	He M (2009), He M (2009)	2
POLR2C	0	TCEA1	0	affinity chromatography technology	Ayguen O (2008)	1
NCOR1	9	NR1D2	1	genetic interference, pull down	Downes M (1996), Muscat GE (1998)	2
CIITA	4	GTF2B	1	pull down	Mahanta SK (1997)	1
TCEA1	0	GTF2B	1	pull down, biochemical	Pan G (1997), Yankulov K (1999)	2
FBL	1	NSUN2	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
POLR2J	0	POLR2E	0	affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Jeronimo C (2004)	2
GTF2F1	0	CTDP1	2	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography	Archambault J (1998), Archambault J (1998), Archambault J (1998), Friedl EM (2003), Nguyen BD (2003)	5
DEPDC7	1	GTF2B	1	two hybrid	Wang J (2011)	1
5430	0	GTF2F1	0	biochemical, pull down, biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, biochemical	Scully R (1997), Scully R (1997), Cho H (1998), Jeronimo C (2007), Friedl EM (2003), Kukalev A (2005), Cujec TP (1997), Havugimana PC (2012)	8
ESR1	0	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
POLR2F	1	POLR2E	0	pull down, biochemical, affinity chromatography technology	Acker J (1997), Wan C (2015), Hein MY (2015)	3
5430	0	CTDP1	2	biochemical, pull down, affinity chromatography technology, enzymatic study, enzymatic study, pull down	Scully R (1997), Scully R (1997), Scully R (1997), Bharucha DC (2002), Friedl EM (2003), Yu X (2003)	6
BCL3	2	JUN	0	two hybrid, pull down, affinity chromatography technology	Na SY (1999), Na SY (1999), Na SY (1999)	3
JUN	0	TBP	0	pull down, pull down	Franklin CC (1995), Franklin CC (1995)	2
CTBP1	2	CREBBP	29	affinity chromatography technology, pull down	Senyuk V (2005), Kim JH (2005)	2
CTDP1	2	MED4	2	pull down	Baillat D (2005)	1
NR1D2	1	GTF2B	1	pull down	Muscat GE (1998)	1
TBP	0	CREBBP	29	affinity chromatography technology	Dallas PB (1997)	1
5430	0	TAF11	0	biochemical, pull down, affinity chromatography technology	Scully R (1997), Scully R (1997), Hofmann WA (2004)	3
CREBBP	29	RELA	1	affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, genetic interference, genetic interference, genetic interference, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, genetic interference, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Jang HD (2004), Zhong H (2002), Zhong H (2002), Parry GC (1997), Parry GC (1997), Parry GC (1997), Aarnisalo P (1998), Gerritsen ME (1997), Gerritsen ME (1997), Gerritsen ME (1997), Gerritsen ME (1997), Liu GH (2008), Vanden Berghe W (1999), Naeaer AM (1999), Merika M (1998), Park J (2007), Verma UN (2004), Verma UN (2004), Verma UN (2004), Johnson J (2007), Aksoy E (2007), Azran I (2005), Silverman ES (1998), Huang WC (2007), Huang WC (2007), Aarnisalo P (1998), Kim HJ (1999), Hsu DS (2014), Chen Y (2015), Huang SM (2002)	30
NXF1	0	DHX9	3	pull down, affinity chromatography technology, biochemical, affinity chromatography technology	Tang H (2000), Tang H (2000), Havugimana PC (2012), Castello A (2012)	4
POLR2C	0	POLR2H	0	pull down, pull down, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Ayguen O (2008), Wan C (2015)	4
ATF4	2	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
RPL10	3	NXF1	0	affinity chromatography technology	Hein MY (2015)	1
GTF2B	1	PKP2	4	affinity chromatography technology	Mertens C (2001)	1
EP300	36	ESR1	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, enzymatic study, affinity chromatography technology, enzymatic study, pull down, pull down	Fajas L (2002), Fan S (2002), Fan S (2002), Fan S (2002), Kang YK (2002), Kang YK (2002), Hao L (2010), Jin W (2008), Cui Y (2006), Dutertre M (2003), Dutertre M (2003), Shiozawa T (2003), Kim SH (2010), Ma Y (2010), Ma Y (2010), Fujita T (2003), Likhite VS (2004), Band AM (2011), Loven MA (2004), Nalvarte I (2010), Yi P (2015)	21
GTF2B	1	SERPINB1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DUSP6	2	GTF2B	1	affinity chromatography technology	Li X (2016)	1
THRA	2	EP300	36	affinity chromatography technology, affinity chromatography technology	De Luca A (2003), De Luca A (2003)	2
GTF2B	1	CST1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HNF4A	2	MED21	1	pull down	Malik S (2002)	1
THRA	2	NCOA1	6	affinity chromatography technology, pull down, two hybrid, pull down, pull down	Sharma D (2000), Lopez GN (1999), Tagami T (1998), Safer JD (1998), Kurtev V (2004)	5
CST1	0	CST4	0	affinity chromatography technology	Huttlin EL (2017)	1
JUN	0	DHX9	3	affinity chromatography technology	Westermarck J (2002)	1
CREBBP	29	GTF2B	1	pull down, pull down	Tini M (2002), Fan S (2002)	2
GTF2B	1	CTDP1	2	affinity chromatography technology	Jeronimo C (2007)	1
SAP25	1	GTF2B	1	affinity chromatography technology	Shiio Y (2006)	1
GTF2E2	2	GTF2E1	1	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, biochemical, x-ray crystallography, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Watanabe T (2003), Maxon ME (1994), Okamoto T (1998), Yamamoto S (2001), Jeronimo C (2007), Havugimana PC (2012), Jawhari A (2006), Jawhari A (2006), Jawhari A (2006), Wan C (2015), Huttlin EL (2017)	11
RPL10	3	FBL	1	affinity chromatography technology	Hein MY (2015)	1
REL	5	CREBBP	29	pull down, affinity chromatography technology	Garbati MR (2010), Garbati MR (2010)	2
FOXF2	1	GTF2B	1	pull down	Hellqvist M (1998)	1
POU3F2	2	TBP	0	two hybrid, pull down	Smit DJ (2000), Smit DJ (2000)	2
RELA	1	JUN	0	two hybrid, genetic interference	Yang X (1999), Yang X (1999)	2
GTF2F2	0	KLF5	4	pull down	Kojima S (1997)	1
PSMA3	1	GTF2B	1	affinity chromatography technology	Fedorova OA (2011)	1
MED4	2	TCEA1	0	affinity chromatography technology	Lambert JP (2015)	1
GTF2F2	0	GTF2F1	0	pull down, biochemical	Wang BQ (1994), Wan C (2015)	2
EP300	36	5430	0	affinity chromatography technology, affinity chromatography technology	Cho H (1998), Fousteri M (2006)	2
GTF2B	1	POLR2E	0	far western blotting, far western blotting, pull down, affinity chromatography technology	Lin Y (1997), Lin Y (1997), Lin Y (1997), Lin Y (1997)	4
GTF2B	1	NSUN2	0	biochemical	Wan C (2015)	1
POLR2G	0	MED21	1	affinity chromatography technology	Hein MY (2015)	1
REST	3	GTF2B	1	pull down	Murai K (2004)	1
RELA	1	PSMC2	2	affinity chromatography technology	Hochrainer K (2015)	1
GTF2E1	1	TAF11	0	pull down, biochemical	Scully R (1997), Scully R (1997)	2
ATF4	2	GTF2B	1	pull down	Liang G (1997)	1
GTF2B	1	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
POLR2G	0	POLR2F	1	pull down, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Huttlin EL (2015), Hein MY (2015)	3
GTF2B	1	NXF1	0	affinity chromatography technology	Yu L (1995)	1
5430	0	GTF2H4	2	biochemical, pull down	Scully R (1997), Scully R (1997)	2
GTF2F1	0	GTF2B	1	biochemical, pull down, pull down, pull down	Scully R (1997), Scully R (1997), Fang SM (1996), Elsby LM (2006)	4
JUN	0	NCOR1	9	imaging technique	Subbaramaiah K (2007)	1
ESR1	0	NCOA1	6	pull down, pull down, pull down, pull down, two hybrid, pull down, affinity chromatography technology, pull down, fluorescent resonance energy transfe, pull down, pull down, two hybrid, pull down, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, two hybrid, fluorescent resonance energy transfe, unspecified method, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, two hybrid, pull down, pull down, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	DiRenzo J (2000), Sheppard HM (2001), Kalkhoven E (1998), Kang YK (2002), Dutertre M (2003), Dutertre M (2003), Shiozawa T (2003), Tremblay A (2001), Llopis J (2000), Chien PY (1999), Webb P (1998), Webb P (1998), Lazennec G (1997), Heery DM (1997), Heery DM (1997), Torchia J (1997), Torchia J (1997), Fleming FJ (2004), Fujita T (2003), Fujita T (2003), Monroe DG (2003), Bai Y (2003), Bramlett KS (2001), Kraichely DM (2000), Kraichely DM (2000), Gong EY (2010), Eng FC (1998), Needham M (2000), Needham M (2000), Chan CM (2013), Kim HJ (1999), Flajollet S (2007), Albers M (2005), Kurtev V (2004), DiRenzo J (1997), Han SJ (2016), Han SJ (2016)	37
ESR1	0	CREBBP	29	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Sheppard HM (2001), Fan S (2002), Fan S (2002), Fan S (2002), Jin W (2008), Jaber BM (2004), Jaber BM (2004), Heery DM (1997), Ku TK (2007), Crowe DL (2006)	10
CTBP1	2	GTF2B	1	pull down	Koipally J (2002)	1
MED21	1	GTF2E1	1	affinity chromatography technology, biochemical	Scully R (1997), Scully R (1997)	2
POLR2E	0	POLR3A	4	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	3
CST2	0	PSMA3	1	two hybrid	Rolland T (2014)	1
CREBBP	29	NCOA1	6	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, pull down	Sheppard HM (2001), Sheppard HM (2001), Sheppard HM (2001), Wu RC (2002), Torchia J (1997), Torchia J (1997), Matsuda S (2004), DiRenzo J (2000), Nakuci E (2006), Ruas JL (2005), Huang SM (2002)	11
SMURF1	4	DHX9	3	affinity chromatography technology	Xie Y (2013)	1
GTF2B	1	POLR2H	0	affinity chromatography technology	Jeronimo C (2007)	1
HNF4A	2	TBP	0	pull down	Green VJ (1998)	1
GTF2B	1	PRB1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
REST	3	TBP	0	pull down, affinity chromatography technology	Murai K (2004), Murai K (2004)	2
JAK3	3	NAP1L1	2	affinity chromatography technology	So J (2015)	1
5430	0	RELA	1	imaging technique	Freaney JE (2013)	1
GTF2F1	0	TBP	0	biochemical, pull down, pull down, enzymatic study	Scully R (1997), Scully R (1997), Ruppert S (1995), Malik S (1998)	4
GTF2B	1	TNIP1	1	two hybrid	Rolland T (2014)	1
CTBP1	2	TBP	0	pull down	Koipally J (2002)	1
FBXO25	1	NAP1L1	2	affinity chromatography technology	Teixeira FR (2010)	1
TBP	0	EP300	36	affinity chromatography technology	Dallas PB (1997)	1
NCOR1	9	EP300	36	affinity chromatography technology	Cowger JJ (2006)	1
POLR2G	0	MED4	2	affinity chromatography technology	Hein MY (2015)	1
GTF2B	1	RFC5	2	biochemical	Wan C (2015)	1
PKP2	4	POLR3A	4	pull down, affinity chromatography technology	Mertens C (2001), Mertens C (2001)	2
KLF5	4	EP300	36	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Miyamoto S (2003), Matsumura T (2005), Guo P (2009), Guo P (2009), Nagai R (2005)	5
HSF1	1	TBP	0	pull down	Yuan CX (2000)	1
TBP	0	TAF9	2	biochemical, affinity chromatography technology, pull down, affinity chromatography technology, biochemical	Bellorini M (1997), Martinez E (2001), Knuesel MT (2009), Liu X (2008), Havugimana PC (2012)	5
GTF2B	1	PIGR	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
POLR2C	0	GTF2F2	0	affinity chromatography technology	Ayguen O (2008)	1
GTF2B	1	THRA	2	pull down	Desai-Yajnik V (1995)	1
THRA	2	MED21	1	affinity chromatography technology, two hybrid, pull down	Ito M (1999), Nevado J (2004), Nevado J (2004)	3
5430	0	POLR2C	0	pull down, pull down, pull down, biochemical, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Knuesel MT (2009), Havugimana PC (2012), Ayguen O (2008), Wan C (2015)	6
HNF4A	2	NCOA1	6	two hybrid	Wang JC (1998)	1
GTF2B	1	JCHAIN	0	affinity chromatography technology	Huttlin EL (2017)	1
GTF2F1	0	GTF2E2	2	pull down, pull down	Okamoto T (1998), Yamamoto S (2001)	2
5430	0	TCEA1	0	x-ray crystallography, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Kettenberger H (2003), Archambault J (1998), Pan G (1997), Jeronimo C (2007), Kim J (2010), Fousteri M (2006), Havugimana PC (2012)	7
POLR2J	0	CTDP1	2	affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Jeronimo C (2004)	2
GTF2B	1	AMY1C	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
POLR2C	0	POLR2G	0	pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Acker J (1997), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	5
NCOR1	9	KLF5	4	affinity chromatography technology, two hybrid	Oishi Y (2008), Oishi Y (2008)	2
GTF2E1	1	GTF2F2	0	pull down	Maxon ME (1994)	1
ESR1	0	POLR2H	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
TBP	0	TAF11	0	biochemical, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, biochemical, biochemical, pull down, affinity chromatography technology	Bellorini M (1997), Mengus G (1995), May M (1996), Knuesel MT (2009), Liu X (2008), Demeny MA (2007), Wieczorek E (1998), Brand M (1999), Gupta K (2017), Gupta K (2017)	10
POLR2J	0	GTF2F1	0	affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Jeronimo C (2004)	2
ATF4	2	TBP	0	pull down	Liang G (1997)	1
MED21	1	GTF2F1	0	affinity chromatography technology, biochemical, affinity chromatography technology	Scully R (1997), Scully R (1997), Sune C (1997)	3
NXF1	0	ATF4	2	affinity chromatography technology	Castello A (2012)	1
POU3F2	2	GTF2B	1	pull down	Smit DJ (2000)	1
NCOR1	9	ESR1	0	pull down, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, imaging technique	Huang HJ (2002), Ku TK (2007), Fujita T (2003), Fujita T (2003), Zhu P (2006), Yoshimaru T (2013)	6
FBL	1	GTF2B	1	biochemical	Wan C (2015)	1
NCOR1	9	TAF9	2	two hybrid, pull down, pull down	Muscat GE (1998), Muscat GE (1998), Muscat GE (1998)	3
IKZF1	2	TBP	0	pull down	Koipally J (2002)	1
POLR2F	1	CTDP1	2	affinity chromatography technology	Hein MY (2015)	1
TBPL1	0	GTF2B	1	pull down	Rabenstein MD (1999)	1
RPL10	3	TBPL1	0	two hybrid	Stelzl U (2005)	1
CTBP1	2	IKZF1	2	pull down, affinity chromatography technology, two hybrid, two hybrid, two hybrid	Koipally J (2000), Koipally J (2000), Vinayagam A (2011), Corominas R (2014), Rolland T (2014)	5
GTF2B	1	SLC22A2	0	two hybrid	Wang J (2011)	1
NCOA1	6	TBP	0	pull down	Takeshita A (1996)	1
5430	0	POLR2H	0	pull down, pull down, pull down, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Knuesel MT (2009), Wu W (2007), Wan C (2015)	5
NXF1	0	GTF2E2	2	affinity chromatography technology	Castello A (2012)	1
RELA	1	GTF2B	1	pull down, pull down	Schmitz ML (1995), Xia C (2004)	2
DHX9	3	GTF2B	1	affinity chromatography technology	Pellizzoni L (2001)	1
5430	0	POLR2E	0	pull down, pull down, pull down, biochemical, biochemical, affinity chromatography technology	Acker J (1997), Acker J (1997), Knuesel MT (2009), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	6
5430	0	POLR2F	1	pull down, pull down, biochemical, affinity chromatography technology	Acker J (1997), Knuesel MT (2009), Wan C (2015), Hein MY (2015)	4
SMURF1	4	ESR1	0	affinity chromatography technology, affinity chromatography technology, pull down	Ito I (2010), Ito I (2010), Ito I (2010)	3
MECP2	36	NCOR1	9	pull down, pull down	Kokura K (2001), Kokura K (2001)	2
ESR1	0	POLR2E	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
POLR2F	1	POLR3A	4	affinity chromatography technology	Hein MY (2015)	1
GTF2B	1	REL	5	pull down	Xu X (1993)	1
POLR2G	0	CTDP1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
DHX9	3	TBP	0	affinity chromatography technology	Pellizzoni L (2001)	1
JUN	0	GTF2B	1	pull down, pull down	Franklin CC (1995), Franklin CC (1995)	2
POLR2C	0	POLR2E	0	pull down, pull down, biochemical, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Havugimana PC (2012), Ayguen O (2008), Wan C (2015)	5
MED4	2	5430	0	bioid	Lambert JP (2015)	1
TBP	0	REL	5	pull down	Xu X (1993)	1
HSF1	1	CREBBP	29	pull down	Hong S (2004)	1
ESR1	0	GTF2B	1	pull down	Lazennec G (1997)	1
LSM4	1	PRPF18	6	biochemical	Havugimana PC (2012)	1
GTF2F1	0	TAF11	0	biochemical, pull down	Scully R (1997), Scully R (1997)	2
HSF1	1	GTF2B	1	pull down	Yuan CX (2000)	1
JUN	0	GTF2F2	0	pull down	Martin ML (1996)	1
TCEA1	0	GTF2F2	0	pull down	Pan G (1997)	1
GTF2B	1	CST4	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BCL3	2	TBP	0	pull down	Na SY (1998)	1
GTF2B	1	NR5A1	1	pull down	Li LA (1999)	1
PSMC2	2	PSMA3	1	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
GTF2B	1	HMGCL	2	two hybrid	Wang J (2011)	1
GTF2B	1	POLR3A	4	affinity chromatography technology	Mertens C (2001)	1
POLR2C	0	POLR2F	1	pull down, pull down, biochemical, affinity chromatography technology	Acker J (1997), Acker J (1997), Wan C (2015), Hein MY (2015)	4
HSF1	1	TAF9	2	pull down	Choi Y (2000)	1
REST	3	NCOR1	9	affinity chromatography technology	Tahiliani M (2007)	1
ATF4	2	POLR2C	0	two hybrid, affinity chromatography technology, pull down	De Angelis R (2003), De Angelis R (2003), De Angelis R (2003)	3
ESR1	0	POLR2F	1	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
BCL3	2	NCOA1	6	two hybrid, pull down	Na SY (1999), Na SY (1999)	2
GTF2B	1	TBP	0	biochemical, pull down, x-ray crystallography, pull down, x-ray crystallography, x-ray crystallography, pull down	Scully R (1997), Scully R (1997), Bushnell DA (2004), Friedman MJ (2007), Tsai FT (2000), Bagby S (1995), Lin Y (1997)	7
GTF2B	1	DRAP1	2	two hybrid	Rolland T (2014)	1
GTF2E2	2	5430	0	affinity chromatography technology, biochemical	Watanabe T (2003), Wan C (2015)	2
POLR2J	0	POLR2G	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Jeronimo C (2004), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	5
MKX	2	TBP	0	affinity chromatography technology	Anderson DM (2009)	1
MED21	1	GTF2B	1	affinity chromatography technology	Sune C (1997)	1
SMURF1	4	5430	0	enzymatic study	Anindya R (2007)	1
MKX	2	GTF2B	1	affinity chromatography technology	Anderson DM (2009)	1
MED21	1	CREBBP	29	affinity chromatography technology	Cho H (1998)	1
GTF2B	1	OXSM	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
5430	0	POLR2G	0	pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Knuesel MT (2009), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
ESR1	0	MED21	1	pull down	Kang YK (2002)	1
NXF1	0	DEPDC7	1	affinity chromatography technology	Castello A (2012)	1
TAF9	2	GTF2B	1	two hybrid, pull down, pull down	Muscat GE (1998), Muscat GE (1998), Muscat GE (1998)	3
POLR2G	0	POLR2H	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Acker J (1997), Hein MY (2015), Huttlin EL (2017)	4
REL	5	RELA	1	affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Hansen SK (1994), Hansen SK (1994), Liss AS (2002), Liss AS (2002), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	8
RPL10	3	DHX9	3	affinity chromatography technology	Hein MY (2015)	1
HNF4A	2	TAF9	2	pull down	Green VJ (1998)	1
EP300	36	GTF2B	1	pull down	Felzien LK (1999)	1
JUN	0	ESR1	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Teyssier C (2001), Baron S (2007), Ruiz ML (2013), Ruiz ML (2013)	4
GTF2B	1	MUC7	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TBP	0	GTF2E2	2	pull down, pull down	Okamoto T (1998), Yamamoto S (2001)	2
POLR2J	0	GTF2B	1	affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Jeronimo C (2004)	2
POU3F2	2	EP300	36	two hybrid, pull down	Smit DJ (2000), Smit DJ (2000)	2
ESR1	0	BCL3	2	affinity chromatography technology	Rubio MF (2006)	1
TAF9	2	RELA	1	pull down	Buss H (2004)	1
NXF1	0	PSMC2	2	affinity chromatography technology	Castello A (2012)	1
NCOA1	6	GTF2B	1	pull down	Takeshita A (1996)	1
GTF2F2	0	POLR2H	0	affinity chromatography technology	Jeronimo C (2007)	1
HNF4A	2	GTF2B	1	pull down	Green VJ (1998)	1
POLR2C	0	GTF2F1	0	affinity chromatography technology	Ayguen O (2008)	1
NR5A1	1	NCOA1	6	two hybrid	Crawford PA (1997)	1
THRA	2	TAF11	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Mengus G (2000), Mengus G (2000), Mengus G (2000)	3
GTF2B	1	ZG16B	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ESR1	0	POLR2C	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
POLR2C	0	CTDP1	2	affinity chromatography technology	Ayguen O (2008)	1
NXF1	0	MED4	2	affinity chromatography technology	Castello A (2012)	1
CIITA	4	EP300	36	affinity chromatography technology	Beaulieu YB (2016)	1
RPL10	3	RFC5	2	affinity chromatography technology	Hein MY (2015)	1
ATF4	2	EP300	36	affinity chromatography technology, pull down, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology	Lassot I (2005), Lassot I (2005), Lassot I (2005), Deng WG (2004), Deng WG (2004), Ohoka N (2007), Deng WG (2003)	7
CREBBP	29	5430	0	biochemical, affinity chromatography technology	Cho H (1998), Cho H (1998)	2
SMURF1	4	GTF2B	1	affinity chromatography technology	Xie Y (2013)	1
GTF2F2	0	POLR2G	0	affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Hein MY (2015)	2
TCEA1	0	GTF2E1	1	pull down, biochemical	Pan G (1997), Yankulov K (1999)	2
TBP	0	KLF5	4	pull down	Kojima S (1997)	1
PSMC2	2	TBP	0	affinity chromatography technology	Yanagi S (2000)	1
ESR1	0	KLF5	4	affinity chromatography technology, affinity chromatography technology, pull down	Guo P (2010), Guo P (2010), Guo P (2010)	3
GTF2B	1	NAP1L1	2	biochemical	Wan C (2015)	1
LSM4	1	LSM5	1	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	3
NR2F1	9	ESR1	0	affinity chromatography technology, pull down, two hybrid, pull down	Metivier R (2002), Metivier R (2002), Metivier R (2002), Klinge CM (1997)	4
POLR2C	0	POLR2J	0	pull down, pull down, two hybrid, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Corbi N (2002), Ayguen O (2008), Wan C (2015)	5
CREBBP	29	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Crusselle-Davis VJ (2007), Dohda T (2004), Dohda T (2004)	3
BCL3	2	GTF2B	1	pull down	Na SY (1998)	1
RELA	1	TBP	0	pull down, pull down, genetic interference, affinity chromatography technology	Guermah M (1998), Schmitz ML (1995), Schmitz ML (1995), Rojo-Niersbach E (2000)	4
GTF2H4	2	TBP	0	biochemical, pull down	Scully R (1997), Scully R (1997)	2
TAF9	2	DRAP1	2	two hybrid, two hybrid, two hybrid, two hybrid	Rual JF (2005), Lim J (2006), Rolland T (2014), Yu H (2011)	4
GTF2F1	0	GTF2E1	1	biochemical, pull down, pull down, affinity chromatography technology	Scully R (1997), Scully R (1997), Maxon ME (1994), Cujec TP (1997)	4
TBP	0	ESR1	0	pull down, pull down	Waernmark A (2001), Lazennec G (1997)	2
GTF2B	1	KLF5	4	pull down	Kojima S (1997)	1
CREBBP	29	HNF4A	2	two hybrid, affinity chromatography technology, pull down, genetic interference, pull down, pull down, enzymatic study, pull down, affinity chromatography technology	Yoshida E (1997), Yoshida E (1997), Yoshida E (1997), Yoshida E (1997), Dell H (1999), Surapureddi S (2008), Soutoglou E (2000), Soutoglou E (2000), Green VJ (1998)	9
NCOR1	9	NCOA1	6	pull down	Stevens A (2003)	1
GTF2B	1	ALKBH2	0	biochemical	Wan C (2015)	1
GTF2B	1	3493	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
5430	0	POLR2J	0	pull down, affinity chromatography technology, biochemical	Knuesel MT (2009), Jeronimo C (2004), Wan C (2015)	3
ESR1	0	POLR2G	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
TBPL1	0	TBP	0	affinity chromatography technology	Jeronimo C (2007)	1
TCEA1	0	TBP	0	pull down, biochemical	Pan G (1997), Yankulov K (1999)	2
GTF2F2	0	GTF2E2	2	pull down	Yamamoto S (2001)	1
RPL10	3	GTF2B	1	affinity chromatography technology	Hein MY (2015)	1
PSMC2	2	CIITA	4	affinity chromatography technology	Bhat KP (2010)	1
POLR2J	0	POLR2H	0	affinity chromatography technology	Jeronimo C (2007)	1
5430	0	TBP	0	biochemical, pull down, affinity chromatography technology, pull down	Scully R (1997), Scully R (1997), McCracken S (1997), Dantonel JC (1997)	4
NCOR1	9	CREBBP	29	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Cowger JJ (2006), Cowger JJ (2006), Cowger JJ (2006), Cowger JJ (2006)	4
TAF9	2	FBL	1	pull down, biochemical	McKeegan KS (2007), Havugimana PC (2012)	2
GTF2B	1	NCOR1	9	pull down, pull down	Muscat GE (1998), Muscat GE (1998)	2
RPL10	3	NSUN2	0	affinity chromatography technology	Hein MY (2015)	1
MED4	2	GTF2B	1	affinity chromatography technology	Lambert JP (2015)	1
ESR1	0	RELA	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Olivier S (2006), Nettles KW (2008), Nettles KW (2008), Rubio MF (2006), Rubio MF (2006)	5
ESR1	0	RPL10	3	affinity chromatography technology	Tarallo R (2011)	1
NR2F1	9	GTF2B	1	pull down	Ing NH (1992)	1
NR1D2	1	TAF9	2	pull down	Muscat GE (1998)	1
ESR1	0	POLR2J	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
GTF2E2	2	KLF5	4	pull down	Kojima S (1997)	1
5430	0	GTF2E1	1	biochemical, pull down, pull down	Scully R (1997), Scully R (1997), Maxon ME (1994)	3
PSMC2	2	GTF2B	1	affinity chromatography technology	Yanagi S (2000)	1
LSM4	1	SLC22A2	0	two hybrid	Wang J (2011)	1
NXF1	0	FBL	1	affinity chromatography technology	Castello A (2012)	1
EP300	36	RELA	1	enzymatic study, two hybrid, affinity chromatography technology, genetic interference, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Gerritsen ME (1997), Gerritsen ME (1997), Gerritsen ME (1997), Gerritsen ME (1997), Hiroi M (2003), Nicot C (2001), Kim RH (2001), Hassa PO (2008), Hassa PO (2008), Hu J (2004), Naeaer AM (1999), Lee IT (2010), Nehra R (2010), Hsu HC (2007), Hsu HC (2007), Saha RN (2007), Saha RN (2007), Hassa PO (2003), Hassa PO (2003), Mendonca DB (2011), Chen W (2008), Chen LF (2002), OHara A (2014), Lu Y (2013), Lu Y (2013), Ren YB (2015), Chen LF (2005), Chen LF (2005), Chen LF (2005), Deng WG (2003)	31
MED21	1	MED4	2	biochemical, bioid, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Lambert JP (2015), Lambert JP (2015), Huttlin EL (2017)	4
NXF1	0	THRA	2	affinity chromatography technology	Castello A (2012)	1
POLR2G	0	GTF2F1	0	affinity chromatography technology	Hein MY (2015)	1
JUN	0	GTF2F1	0	pull down	Martin ML (1996)	1
5430	0	GTF2F2	0	biochemical, affinity chromatography technology, biochemical	Sopta M (1985), Jeronimo C (2007), Wan C (2015)	3
MED4	2	GTF2F1	0	affinity chromatography technology	Lambert JP (2015)	1
NCOA4	4	ESR1	0	pull down	Alen P (1999)	1
TAF11	0	TAF9	2	affinity chromatography technology	Gupta K (2017)	1
ATF4	2	CREBBP	29	pull down, affinity chromatography technology, imaging technique	Liang G (1997), Venza I (2001), Chen TC (2014)	3
FBXO25	1	GTF2B	1	enzymatic study	Teixeira FR (2013)	1
EP300	36	NAP1L1	2	two hybrid	Shikama N (2000)	1
ESR1	0	5430	0	affinity chromatography technology, imaging technique, imaging technique, pull down	Ambrosino C (2010), Zhang H (2006), Zhang H (2006), Nalvarte I (2010)	4
GTF2B	1	GTF2H4	2	biochemical, pull down	Scully R (1997), Scully R (1997)	2
POLR2G	0	TCEA1	0	affinity chromatography technology	Hein MY (2015)	1
IKZF1	2	LSM4	1	two hybrid	Rolland T (2014)	1
POLR2E	0	POLR2H	0	pull down, pull down, biochemical, biochemical	Acker J (1997), Acker J (1997), Kristensen AR (2012), Wan C (2015)	4
CIITA	4	TAF9	2	pull down	Mahanta SK (1997)	1
TBP	0	GTF2F2	0	pull down	Tang H (1996)	1
TCEA1	0	GTF2F1	0	pull down, biochemical	Pan G (1997), Yankulov K (1999)	2
FOXF2	1	TBP	0	pull down, pull down	Hellqvist M (1998), Hellqvist M (1998)	2
MED21	1	GTF2H4	2	affinity chromatography technology, biochemical	Scully R (1997), Scully R (1997)	2
GTF2B	1	3514	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
IKZF1	2	GTF2B	1	pull down	Koipally J (2002)	1
GTF2B	1	CST2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
POLR2F	1	GTF2B	1	affinity chromatography technology	Hein MY (2015)	1
5430	0	MED21	1	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scully R (1997), Scully R (1997), Cho H (1998), Cho H (1998), Sune C (1997), Huttlin EL (2017)	6
CTBP1	2	EP300	36	affinity chromatography technology, pull down, affinity chromatography technology, pull down	Senyuk V (2005), Kim JH (2005), Kim JH (2005), Kim JH (2005)	4
POLR2G	0	GTF2B	1	affinity chromatography technology	Hein MY (2015)	1
THRA	2	NCOR1	9	affinity chromatography technology, pull down, pull down, two hybrid, pull down, affinity chromatography technology, pull down, two hybrid, pull down	Rietveld LE (2002), Ishii S (2004), Tagami T (1998), Tagami T (1998), Safer JD (1998), Jeyakumar M (2007), Jeyakumar M (2007), Albers M (2005), Hoerlein AJ (1995)	9
POLR2F	1	GTF2F1	0	affinity chromatography technology	Hein MY (2015)	1
GTF2E1	1	GTF2H4	2	pull down, biochemical	Scully R (1997), Scully R (1997)	2
DHX9	3	5430	0	affinity chromatography technology, affinity chromatography technology	Tang W (2009), Fujita H (2003)	2
KLF5	4	CREBBP	29	pull down, two hybrid	Zhang Z (2003), Oishi Y (2008)	2
POLR3A	4	5430	0	biochemical	Wan C (2015)	1
GTF2F2	0	POLR2E	0	pull down, affinity chromatography technology, biochemical	Wei W (2001), Wei W (2001), Wan C (2015)	3
GTF2B	1	JAK3	3	two hybrid	Wang J (2011)	1
POLR2F	1	POLR2J	0	affinity chromatography technology	Hein MY (2015)	1
POLR2J	0	GTF2F2	0	affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Jeronimo C (2004)	2
MECP2	36	GTF2B	1	pull down	Kaludov NK (2000)	1
POLR2H	0	POLR3A	4	affinity chromatography technology, biochemical, biochemical	Wu W (2007), Havugimana PC (2012), Wan C (2015)	3
POLR2C	0	GTF2B	1	affinity chromatography technology	Ayguen O (2008)	1
GTF2E1	1	GTF2B	1	pull down, biochemical	Scully R (1997), Scully R (1997)	2
GTF2B	1	283458	0	affinity chromatography technology	Huttlin EL (2015)	1
POLR2E	0	POLR2G	0	pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Acker J (1997), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	5
5430	0	GTF2B	1	biochemical, pull down, affinity chromatography technology	Scully R (1997), Scully R (1997), Jeronimo C (2007)	3
MED21	1	POLR2J	0	affinity chromatography technology	Huttlin EL (2017)	1
CIITA	4	NCOA1	6	affinity chromatography technology, pull down	Tzortzakaki E (2003), Tzortzakaki E (2003)	2
DHX9	3	RELA	1	affinity chromatography technology, pull down, two hybrid	Tetsuka T (2004), Tetsuka T (2004), Tetsuka T (2004)	3
EP300	36	JUN	0	pull down, biochemical, x-ray crystallography, affinity chromatography technology, pull down, enzymatic study, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Campbell KM (2002), Campbell KM (2002), Campbell KM (2002), Subbaramaiah K (2002), Duyndam MC (1999), Wang WM (2011), Deng WG (2004), Deng WG (2004), Cheng SE (2011), Cheng SE (2011), Kim BK (2014), Vries RG (2001), Deng WG (2003), Liu L (2017), Liu L (2017)	15
JUN	0	GTF2E2	2	pull down	Martin ML (1996)	1
DRAP1	2	TBP	0	x-ray crystallography, affinity chromatography technology, pull down	Kamada K (2001), Gilfillan S (2005), Wang YL (2008)	3
ATF4	2	GTF2F2	0	pull down	Liang G (1997)	1
POLR2F	1	GTF2F2	0	affinity chromatography technology	Hein MY (2015)	1
GTF2E1	1	NSUN2	0	biochemical	Kristensen AR (2012)	1
EP300	36	HSF1	1	affinity chromatography technology	Huang C (2017)	1
BCL3	2	EP300	36	two hybrid, pull down	Na SY (1999), Na SY (1999)	2
NCOA1	6	EP300	36	affinity chromatography technology, imaging technique, pull down, pull down	Matsuda S (2004), Wang F (2010), Kino T (2002), Nasrin N (2000)	4
CREBBP	29	JUN	0	pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, far western blotting	Sano Y (1998), Sano Y (1998), Merika M (1998), Duyndam MC (1999), Johnson J (2007), Yamaguchi K (2005), Tsai LN (2008), Arias J (1994)	8
LSM5	1	GTF2B	1	biochemical	Havugimana PC (2012)	1
NXF1	0	5430	0	affinity chromatography technology	Castello A (2012)	1
JUN	0	NR5A1	1	pull down	Li LA (1999)	1
RELA	1	TAF11	0	pull down	Guermah M (1998)	1
TCEA1	0	CTDP1	2	pull down	Archambault J (1998)	1
GTF2B	1	TAF11	0	biochemical, pull down	Scully R (1997), Scully R (1997)	2
PSMC2	2	GTF2F1	0	affinity chromatography technology	Yanagi S (2000)	1
NCOA4	4	GTF2B	1	pull down	Alen P (1999)	1
GTF2E2	2	GTF2B	1	affinity chromatography technology, pull down	Watanabe T (2003), Yamamoto S (2001)	2
GTF2F1	0	GTF2H4	2	biochemical, pull down	Scully R (1997), Scully R (1997)	2
ESR1	0	DHX9	3	affinity chromatography technology, pull down	Tarallo R (2011), Nalvarte I (2010)	2
GTF2B	1	GTF2F2	0	pull down, pull down, biochemical	Fang SM (1996), Elsby LM (2006), Wan C (2015)	3
REL	5	EP300	36	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Garbati MR (2010), Garbati MR (2010), Haery L (2014), Haery L (2014), Haery L (2014)	5
NCOA1	6	JUN	0	pull down, pull down, two hybrid, pull down	Lee SK (1999), Lee SK (2000), Lee SK (1998), Lee SK (1998)	4