PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
BRCA1	7	MED21	1	biochemical, affinity chromatography technology	Scully R (1997), Scully R (1997)	2
EXOSC4	1	XRN2	1	genetic interference	Horlbeck MA (2018)	1
CCNH	3	GTF2H4	2	biochemical	Havugimana PC (2012)	1
EMC1	5	GTF2H4	2	genetic interference	Horlbeck MA (2018)	1
LEO1	3	NFYC	0	genetic interference	Horlbeck MA (2018)	1
GEMIN2	1	GTF2H4	2	genetic interference	Horlbeck MA (2018)	1
MED14	0	MED17	0	affinity chromatography technology, biochemical, biochemical	Ryu S (1999), Havugimana PC (2012), Wan C (2015)	3
GTF2E1	1	TBP	0	pull down, biochemical, pull down	Scully R (1997), Scully R (1997), Maxon ME (1994)	3
CDK7	0	GTF2H1	0	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Rossignol M (1997), Shiekhattar R (1995), Yee A (1995), Kershnar E (1998), Reardon JT (1996), Varjosalo M (2013)	6
BRCA1	7	5430	0	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Krum SA (2003), Scully R (1997), Scully R (1997), Chiba N (2001), Chiba N (2001), Krum SA (2003), Starita LM (2005), Woods NT (2012), Bennett CB (2008), Hill SJ (2014), Winton CE (2016)	11
GTF2H4	2	XRN2	1	genetic interference	Horlbeck MA (2018)	1
GTF2H2	0	GTF2H4	2	affinity chromatography technology, biochemical, biochemical, pull down	Vermeulen W (2000), Havugimana PC (2012), Wan C (2015), Luo J (2015)	4
BRCA1	7	GTF2F1	0	biochemical	Scully R (1997)	1
GTF2H1	0	GTF2H4	2	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
EXOSC4	1	MED17	0	affinity chromatography technology	Hein MY (2015)	1
GTF2H5	0	MNAT1	0	affinity chromatography technology	Hein MY (2015)	1
GEMIN4	2	MED14	0	genetic interference	Horlbeck MA (2018)	1
TP53	0	RPLP2	0	affinity chromatography technology	Fogeron ML (2013)	1
GTF2H4	2	RBM17	1	genetic interference	Horlbeck MA (2018)	1
BRCA1	7	MYC	2	affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Li H (2002), Xiong J (2003), Xiong J (2003), Wang Q (1998), Wang Q (1998), Wang Q (1998), Harte MT (2010), Harte MT (2010), Xiong J (2003), Xiong J (2003), Zhou C (2003)	11
GTF2H3	2	GTF2H1	0	pull down, biochemical, affinity chromatography technology, pull down, biochemical, biochemical, affinity chromatography technology, pull down	Chymkowitch P (2011), Humbert S (1994), Humbert S (1994), Jawhari A (2002), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017), Luo J (2015)	8
730394	0	CDK7	0	affinity chromatography technology	Huttlin EL (2017)	1
GFI1B	1	MED14	0	genetic interference	Horlbeck MA (2018)	1
TP53	0	GTF2H4	2	far western blotting	Leveillard T (1996)	1
5430	0	GTF2F1	0	biochemical, pull down, biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, biochemical	Scully R (1997), Scully R (1997), Cho H (1998), Jeronimo C (2007), Friedl EM (2003), Kukalev A (2005), Cujec TP (1997), Havugimana PC (2012)	8
GTF2H1	0	GTF2E1	1	pull down, x-ray crystallography, pull down, pull down	Di Lello P (2008), Okuda M (2008), Okuda M (2008), Okuda M (2008)	4
GEMIN4	2	GFI1B	1	genetic interference	Horlbeck MA (2018)	1
ERCC3	3	CDK7	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Giglia-Mari G (2004), Rossignol M (1997), Yee A (1995), Jeronimo C (2007), Jeronimo C (2007), Reardon JT (1996), Chen D (1999), Varjosalo M (2013), Huttlin EL (2017), Luo J (2015)	10
GTF2H4	2	KDM1A	2	genetic interference	Horlbeck MA (2018)	1
RNF11	0	GTF2H4	2	affinity chromatography technology	Poulsen SL (2013)	1
LEO1	3	RBM17	1	genetic interference	Horlbeck MA (2018)	1
ADPRM	1	GTF2H4	2	genetic interference	Horlbeck MA (2018)	1
CDK7	0	CCNH	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down	Maekelae TP (1994), Maekelae TP (1994), Maekelae TP (1994), Maekelae TP (1994), Yee A (1995), Garber ME (2000), Garber ME (2000), Jeronimo C (2007), Reardon JT (1996), Liu J (1997), Cujec TP (1997), Epie N (2005), Bockstaele L (2006), Tassan JP (1995), Chen D (1999), Havugimana PC (2012), Poterszman A (1997), Nguyen VT (2001), Garrett S (2001), Pinhero R (2004), Varjosalo M (2013), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Luo J (2015)	25
7495	0	MNAT1	0	affinity chromatography technology	Busso D (2000)	1
BRCA1	7	KDM1A	2	two hybrid, affinity chromatography technology, affinity chromatography technology	Woods NT (2012), Woods NT (2012), Ertych N (2016)	3
MNAT1	0	GTF2H3	2	biochemical	Havugimana PC (2012)	1
MYC	2	TBP	0	pull down	McEwan IJ (1996)	1
TBP	0	NFYC	0	pull down	Bellorini M (1997)	1
RPLP2	0	MRPS21	1	biochemical	Wan C (2015)	1
ERCC3	3	CCNH	3	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Giglia-Mari G (2004), Jeronimo C (2007), Drapkin R (1996), Drapkin R (1996), Huttlin EL (2015), Huttlin EL (2017), Luo J (2015)	7
EXOSC4	1	GTF2E1	1	genetic interference	Horlbeck MA (2018)	1
GTF2H4	2	MED17	0	genetic interference	Horlbeck MA (2018)	1
GTF2H1	0	GTF2H2C	0	biochemical	Wan C (2015)	1
GTF2H4	2	RPL24	0	genetic interference	Horlbeck MA (2018)	1
GTF2H5	0	CDK7	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Giglia-Mari G (2004), Varjosalo M (2013), Hein MY (2015)	3
ERCC3	3	GTF2H3	2	biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Giglia-Mari G (2004), Marinoni JC (1997), Jeronimo C (2007), Humbert S (1994), Humbert S (1994), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017), Luo J (2015)	9
GTF2H4	2	WDR70	1	genetic interference	Horlbeck MA (2018)	1
BTAF1	6	TBP	0	pull down, affinity chromatography technology, pull down, biochemical	Scully R (1997), Chicca JJ (1998), Chicca JJ (1998), Havugimana PC (2012)	4
BRCA1	7	GTF2E1	1	biochemical	Scully R (1997)	1
GTF2H1	0	MNAT1	0	biochemical, biochemical, pull down	Kershnar E (1998), Havugimana PC (2012), Luo J (2015)	3
GEMIN4	2	LEO1	3	genetic interference	Horlbeck MA (2018)	1
MNAT1	0	BRCA1	7	affinity chromatography technology, two hybrid	Moisan A (2004), Woodsmith J (2012)	2
EMC7	1	EMC4	1	affinity chromatography technology, affinity chromatography technology, genetic interference	Christianson JC (2012), Huttlin EL (2017), Horlbeck MA (2018)	3
BRCA1	7	RPL24	0	affinity chromatography technology	Ertych N (2016)	1
5430	0	GTF2H4	2	biochemical, pull down	Scully R (1997), Scully R (1997)	2
GTF2F1	0	GTF2B	1	biochemical, pull down, pull down, pull down	Scully R (1997), Scully R (1997), Fang SM (1996), Elsby LM (2006)	4
EMC1	5	EMC4	1	affinity chromatography technology	Christianson JC (2012)	1
5430	0	LEO1	3	pull down, pull down	Kim J (2010), Kim J (2010)	2
MYC	2	RNGTT	0	affinity chromatography technology	Koch HB (2007)	1
MED21	1	GTF2E1	1	affinity chromatography technology, biochemical	Scully R (1997), Scully R (1997)	2
GTF2H4	2	KIF14	8	genetic interference	Horlbeck MA (2018)	1
CDK7	0	BRCA1	7	affinity chromatography technology	Moisan A (2004)	1
KDM1A	2	LEO1	3	genetic interference	Horlbeck MA (2018)	1
KDM1A	2	RPL24	0	genetic interference	Horlbeck MA (2018)	1
GTF2H4	2	SNAPC1	0	genetic interference	Horlbeck MA (2018)	1
TP53	0	GTF2H1	0	pull down, pull down, pull down, pull down, far western blotting, pull down, x-ray crystallography	Xiao H (1994), Di Lello P (2008), Okuda M (2008), Leveillard T (1996), Leveillard T (1996), Di Lello P (2006), Di Lello P (2006)	7
CCNH	3	MNAT1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, biochemical, affinity chromatography technology	Ewing RM (2007), Talukder AH (2003), Bockstaele L (2006), Havugimana PC (2012), Pinhero R (2004), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	8
GTF2F1	0	TBP	0	biochemical, pull down, pull down, enzymatic study	Scully R (1997), Scully R (1997), Ruppert S (1995), Malik S (1998)	4
EXOSC4	1	SNAPC1	0	genetic interference	Horlbeck MA (2018)	1
XRN2	1	MRPS10	1	two hybrid	Lehner B (2004)	1
GTF2H4	2	LEO1	3	genetic interference	Horlbeck MA (2018)	1
GTF2H5	0	GTF2H1	0	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
BRCA1	7	RPLP2	0	affinity chromatography technology	Ertych N (2016)	1
MED14	0	MINOS1-NBL1	0	genetic interference	Horlbeck MA (2018)	1
730394	0	GTF2H4	2	affinity chromatography technology, biochemical, affinity chromatography technology	Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	3
HUS1	1	XRN2	1	genetic interference	Horlbeck MA (2018)	1
GTF2H4	2	RNGTT	0	genetic interference	Horlbeck MA (2018)	1
EMC7	1	EMC1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Christianson JC (2012), Christianson JC (2012), Huttlin EL (2017)	3
KIF14	8	MINOS1-NBL1	0	genetic interference	Horlbeck MA (2018)	1
MED17	0	TP53	0	pull down	Ito M (1999)	1
BTAF1	6	GTF2H4	2	biochemical	Scully R (1997)	1
GTF2H1	0	CCNH	3	biochemical, biochemical, affinity chromatography technology	Shiekhattar R (1995), Kershnar E (1998), Araujo SJ (2001)	3
GTF2H3	2	730394	0	two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Rolland T (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	4
MYC	2	GEMIN4	2	affinity chromatography technology	Ewing RM (2007)	1
LEO1	3	MRPS10	1	genetic interference	Horlbeck MA (2018)	1
MYC	2	ERCC3	3	affinity chromatography technology	Koch HB (2007)	1
MNAT1	0	GTF2H2	0	affinity chromatography technology, pull down	Drapkin R (1996), Luo J (2015)	2
MED21	1	GTF2F1	0	affinity chromatography technology, biochemical, affinity chromatography technology	Scully R (1997), Scully R (1997), Sune C (1997)	3
GTF2H4	2	SFXN1	0	genetic interference	Horlbeck MA (2018)	1
MNAT1	0	5430	0	enzymatic study, enzymatic study	Larochelle S (2006), Lolli G (2004)	2
CDK7	0	MNAT1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down	Talukder AH (2003), Yee A (1995), Jeronimo C (2007), Busso D (2000), Cujec TP (1997), Tassan JP (1995), Chen D (1999), Havugimana PC (2012), Varjosalo M (2013), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Luo J (2015)	13
GFI1B	1	KDM1A	2	affinity chromatography technology	Saleque S (2007)	1
CDK7	0	GTF2H3	2	affinity chromatography technology, pull down, affinity chromatography technology	Jeronimo C (2007), Chymkowitch P (2011), Varjosalo M (2013)	3
RPL24	0	SNAPC1	0	genetic interference	Horlbeck MA (2018)	1
GTF2E1	1	MED17	0	genetic interference	Horlbeck MA (2018)	1
TP53	0	ERCC3	3	pull down, affinity chromatography technology, pull down, pull down, pull down	Wang XW (1995), Wang XW (1995), Qadri I (2002), Qadri I (2002), Leveillard T (1996)	5
BRCA1	7	TCOF1	1	affinity chromatography technology	Ertych N (2016)	1
730394	0	ERCC3	3	affinity chromatography technology, biochemical, affinity chromatography technology	Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	3
ERCC3	3	GTF2H1	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Giglia-Mari G (2004), Marinoni JC (1997), Rossignol M (1997), Jeronimo C (2007), Drapkin R (1996), Araujo SJ (2001), Havugimana PC (2012), Maru Y (1999), Wan C (2015), Huttlin EL (2017), Luo J (2015), Luo J (2015)	12
GTF2H4	2	MRPL27	1	genetic interference	Horlbeck MA (2018)	1
GTF2H3	2	GTF2H2	0	pull down, affinity chromatography technology, pull down, biochemical, biochemical, affinity chromatography technology, pull down	Chymkowitch P (2011), Kellenberger E (2005), Jawhari A (2002), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017), Luo J (2015)	7
GTF2H1	0	5430	0	enzymatic study, biochemical, enzymatic study	Moisan A (2004), Yankulov K (1999), Parada CA (1996)	3
MNAT1	0	GTF2H4	2	biochemical	Havugimana PC (2012)	1
KIF14	8	TCOF1	1	genetic interference	Horlbeck MA (2018)	1
KDM1A	2	SNAPC1	0	genetic interference	Horlbeck MA (2018)	1
GEMIN2	1	SNAPC1	0	genetic interference	Horlbeck MA (2018)	1
GTF2H4	2	SCO1	0	genetic interference	Horlbeck MA (2018)	1
LEO1	3	SNAPC1	0	genetic interference	Horlbeck MA (2018)	1
EXOSC4	1	GTF2H4	2	genetic interference	Horlbeck MA (2018)	1
GTF2H2	0	GTF2H5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Giglia-Mari G (2004), Vermeulen W (2000), Giglia-Mari G (2006), Hein MY (2015), Huttlin EL (2017)	5
730394	0	GTF2H2C	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GTF2H4	2	MZT1	1	genetic interference	Horlbeck MA (2018)	1
LEO1	3	RPLP2	0	genetic interference	Horlbeck MA (2018)	1
RNGTT	0	TCOF1	1	genetic interference	Horlbeck MA (2018)	1
GTF2H4	2	MINOS1-NBL1	0	genetic interference	Horlbeck MA (2018)	1
MYC	2	CCNH	3	pull down	Eberhardy SR (2001)	1
KDM1A	2	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study	Tsai WW (2008), Tsai WW (2008), Huang J (2007), Huang J (2007), Huang J (2007), Huang J (2007), Huang J (2007)	7
MYC	2	GTF2F1	0	pull down	McEwan IJ (1996)	1
GEMIN2	1	GEMIN4	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Piazzon N (2012), Piazzon N (2012), Huttlin EL (2017), Horlbeck MA (2018)	4
GTF2B	1	TBP	0	biochemical, pull down, x-ray crystallography, pull down, x-ray crystallography, x-ray crystallography, pull down	Scully R (1997), Scully R (1997), Bushnell DA (2004), Friedman MJ (2007), Tsai FT (2000), Bagby S (1995), Lin Y (1997)	7
GTF2E1	1	ERCC3	3	pull down, pull down	Maxon ME (1994), Maxon ME (1994)	2
CCNH	3	BRCA1	7	affinity chromatography technology	Moisan A (2004)	1
MED21	1	GTF2B	1	affinity chromatography technology	Sune C (1997)	1
MED21	1	CDK7	0	affinity chromatography technology	Sune C (1997)	1
NFYC	0	MYC	2	pull down, two hybrid, affinity chromatography technology	Taira T (1999), Taira T (1999), Taira T (1999)	3
ERCC3	3	GTF2H2	0	biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down	Giglia-Mari G (2004), Marinoni JC (1997), Jeronimo C (2007), Humbert S (1994), Humbert S (1994), Wan C (2015), Huttlin EL (2017), Luo J (2015), Luo J (2015)	9
ERCC3	3	GTF2H4	2	biochemical, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, pull down	Giglia-Mari G (2004), Marinoni JC (1997), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017), Luo J (2015), Luo J (2015)	7
GTF2H4	2	MED14	0	genetic interference	Horlbeck MA (2018)	1
GTF2H5	0	ERCC3	3	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Giglia-Mari G (2004), Giglia-Mari G (2004), Giglia-Mari G (2006), Hein MY (2015), Huttlin EL (2017), Luo J (2015)	6
BRCA1	7	GTF2H4	2	biochemical	Scully R (1997)	1
CDK7	0	GTF2H4	2	affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Varjosalo M (2013)	2
HUS1	1	NFYC	0	genetic interference	Horlbeck MA (2018)	1
BRCA1	7	MED17	0	biochemical, biochemical	Chiba N (2001), Chiba N (2002)	2
MYC	2	5430	0	affinity chromatography technology	Koch HB (2007)	1
TP53	0	CCNH	3	far western blotting, affinity chromatography technology	Schneider E (1998), Schneider E (1998)	2
RPL24	0	RPLP2	0	biochemical	Wan C (2015)	1
5430	0	ERCC3	3	affinity chromatography technology	Fousteri M (2006)	1
GTF2H5	0	CCNH	3	affinity chromatography technology	Hein MY (2015)	1
GTF2H4	2	TBP	0	biochemical, pull down	Scully R (1997), Scully R (1997)	2
CDK7	0	TP53	0	enzymatic study, affinity chromatography technology, enzymatic study, pull down	Ko LJ (1997), Schneider E (1998), Lu H (1997), Lu H (1997)	4
TP53	0	EXOSC4	1	genetic interference	Xie L (2013)	1
GTF2F1	0	GTF2E1	1	biochemical, pull down, pull down, affinity chromatography technology	Scully R (1997), Scully R (1997), Maxon ME (1994), Cujec TP (1997)	4
GTF2H4	2	NIP7	2	genetic interference	Horlbeck MA (2018)	1
GFI1B	1	GTF2H4	2	genetic interference	Horlbeck MA (2018)	1
GTF2H2C	0	GTF2H4	2	biochemical	Wan C (2015)	1
EMC7	1	GTF2H4	2	genetic interference	Horlbeck MA (2018)	1
MED21	1	MED14	0	biochemical, biochemical, affinity chromatography technology	Sun X (1998), Havugimana PC (2012), Huttlin EL (2017)	3
BRCA1	7	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, biochemical, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2004), Ouchi T (1998), Dong Y (2003), Dong Y (2003), Chai YL (1999), Chai YL (1999), Zhang H (1998), Dong Y (2003), Chen Y (2006), Quaresima B (2006), Zhang H (1998), Zhang H (1998), Mark WY (2005), Jin S (2009), Jiang J (2011), Rasti M (2015), Rasti M (2015)	17
GFI1B	1	LEO1	3	genetic interference	Horlbeck MA (2018)	1
GTF2H4	2	RPLP2	0	genetic interference	Horlbeck MA (2018)	1
TP53	0	MNAT1	0	pull down, affinity chromatography technology	Ko LJ (1997), Ko LJ (1997)	2
5430	0	TBP	0	biochemical, pull down, affinity chromatography technology, pull down	Scully R (1997), Scully R (1997), McCracken S (1997), Dantonel JC (1997)	4
GTF2H2	0	CDK7	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vermeulen W (2000), Jeronimo C (2007), Varjosalo M (2013)	3
MYC	2	TP53	0	affinity chromatography technology, fluorescent resonance energy transfe	Agrawal P (2010), Ivanov AA (2017)	2
GTF2H4	2	MRPS10	1	genetic interference	Horlbeck MA (2018)	1
5430	0	GTF2E1	1	biochemical, pull down, pull down	Scully R (1997), Scully R (1997), Maxon ME (1994)	3
GTF2H4	2	NFYC	0	genetic interference	Horlbeck MA (2018)	1
GTF2H3	2	7495	0	pull down	Jawhari A (2002)	1
GTF2H4	2	HUS1	1	genetic interference	Horlbeck MA (2018)	1
CCNH	3	5430	0	enzymatic study, biochemical, enzymatic study	Chen R (2004), Nekhai S (1997), Lolli G (2004)	3
XRN2	1	5430	0	affinity chromatography technology, affinity chromatography technology	Li S (2014), Zhao DY (2016)	2
LEO1	3	MRPL27	1	genetic interference	Horlbeck MA (2018)	1
GTF2H5	0	GTF2H4	2	affinity chromatography technology, affinity chromatography technology, pull down	Hein MY (2015), Huttlin EL (2017), Luo J (2015)	3
RBM17	1	SNAPC1	0	genetic interference	Horlbeck MA (2018)	1
HUS1	1	LEO1	3	genetic interference	Horlbeck MA (2018)	1
GTF2H4	2	TCOF1	1	genetic interference	Horlbeck MA (2018)	1
GEMIN4	2	GTF2E1	1	genetic interference	Horlbeck MA (2018)	1
TBP	0	TP53	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Seto E (1992), Cvekl A (1999), Wu Y (2001), Qadri I (2002), Qadri I (2002), Sommer MH (1994)	6
GTF2B	1	GTF2H4	2	biochemical, pull down	Scully R (1997), Scully R (1997)	2
LEO1	3	MRPS21	1	genetic interference	Horlbeck MA (2018)	1
TBP	0	SNAPC1	0	pull down	Yoon JB (1996)	1
RNF11	0	GTF2H1	0	affinity chromatography technology	Poulsen SL (2013)	1
GTF2H4	2	MRPS21	1	genetic interference	Horlbeck MA (2018)	1
BRCA1	7	RNGTT	0	affinity chromatography technology	Woods NT (2012)	1
LEO1	3	RPL24	0	genetic interference	Horlbeck MA (2018)	1
TP53	0	RPL24	0	affinity chromatography technology	Fogeron ML (2013)	1
GTF2H3	2	GTF2H2C	0	biochemical	Wan C (2015)	1
ERCC3	3	MNAT1	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Giglia-Mari G (2004), Jeronimo C (2007), Drapkin R (1996), Drapkin R (1996), Huttlin EL (2017), Luo J (2015), Luo J (2015)	7
GTF2H5	0	GTF2H3	2	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
MED21	1	GTF2H4	2	affinity chromatography technology, biochemical	Scully R (1997), Scully R (1997)	2
GFI1B	1	BRCA1	7	two hybrid	Lim J (2006)	1
5430	0	MED21	1	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scully R (1997), Scully R (1997), Cho H (1998), Cho H (1998), Sune C (1997), Huttlin EL (2017)	6
RBM17	1	XRN2	1	genetic interference	Horlbeck MA (2018)	1
GTF2E1	1	GTF2H4	2	pull down, biochemical	Scully R (1997), Scully R (1997)	2
EXOSC4	1	HUS1	1	genetic interference	Horlbeck MA (2018)	1
LEO1	3	WDR70	1	genetic interference	Horlbeck MA (2018)	1
GEMIN4	2	GTF2H1	0	genetic interference	Horlbeck MA (2018)	1
MYC	2	KDM1A	2	two hybrid	Weimann M (2013)	1
GTF2E1	1	GTF2B	1	pull down, biochemical	Scully R (1997), Scully R (1997)	2
MYC	2	GTF2H4	2	genetic interference	Toyoshima M (2012)	1
CDK7	0	5430	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, biochemical, enzymatic study, enzymatic study, enzymatic study	Drapkin R (1996), Gegonne A (2008), Moisan A (2004), Pinhero R (2004), Ramanathan Y (2001), Larochelle S (2012), Larochelle S (2006), Nekhai S (1997), Pinhero R (2004), Rovnak J (2012), Lolli G (2004)	11
5430	0	GTF2B	1	biochemical, pull down, affinity chromatography technology	Scully R (1997), Scully R (1997), Jeronimo C (2007)	3
EMC4	1	GTF2H4	2	genetic interference	Horlbeck MA (2018)	1
GEMIN4	2	RPL24	0	genetic interference	Horlbeck MA (2018)	1
RNGTT	0	5430	0	affinity chromatography technology	St-Denis N (2016)	1
TP53	0	MED21	1	pull down	Gu W (1999)	1
GEMIN4	2	GTF2H4	2	genetic interference	Horlbeck MA (2018)	1
GTF2H4	2	GTF2H4	2	genetic interference	Horlbeck MA (2018)	1
ERCC3	3	GTF2H2C	0	biochemical	Wan C (2015)	1
GTF2F1	0	GTF2H1	0	affinity chromatography technology	Cujec TP (1997)	1
CDK7	0	GTF2E1	1	enzymatic study, enzymatic study	Moisan A (2004), Larochelle S (2012)	2
GTF2H3	2	GTF2H4	2	pull down, biochemical, biochemical, affinity chromatography technology, pull down	Jawhari A (2002), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017), Luo J (2015)	5
GTF2E1	1	MZT1	1	genetic interference	Horlbeck MA (2018)	1
NFYC	0	SNAPC1	0	genetic interference	Horlbeck MA (2018)	1
GTF2H2	0	GTF2H1	0	affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid, biochemical, pull down	Vermeulen W (2000), Humbert S (1994), Humbert S (1994), Wang J (2011), Wan C (2015), Luo J (2015)	6
730394	0	GTF2H5	0	affinity chromatography technology	Huttlin EL (2017)	1
7495	0	GTF2H4	2	pull down, pull down	Jawhari A (2002), Jawhari A (2002)	2
730394	0	GTF2H1	0	affinity chromatography technology, biochemical, affinity chromatography technology	Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	3
GTF2F1	0	GTF2H4	2	biochemical, pull down	Scully R (1997), Scully R (1997)	2
BRCA1	7	XRN2	1	affinity chromatography technology	Ertych N (2016)	1
MED17	0	MED21	1	biochemical, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2017)	2
GTF2H2	0	CCNH	3	affinity chromatography technology	Vermeulen W (2000)	1