PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
ELAVL1	0	TP53	0	affinity chromatography technology	Galban S (2003)	1
TP53	0	SENP1	0	affinity chromatography technology	Wu SY (2009)	1
HNRNPL	3	APP	1	affinity chromatography technology	Fei T (2017)	1
HNRNPL	3	SCARA3	2	affinity chromatography technology	Fei T (2017)	1
NUP153	1	RANGAP1	4	affinity chromatography technology	Hein MY (2015)	1
LMNA	2	SENP1	0	bioid, bioid	Roux KJ (2012), Kim DI (2014)	2
KPNB1	3	NUP153	1	pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nakielny S (1999), Nakielny S (1999), Kehlenbach RH (2000), Ben-Efraim I (2001), Walther TC (2003), Ciciarello M (2010), Hein MY (2015), Hein MY (2015)	8
GCM1	2	HDAC1	4	affinity chromatography technology, affinity chromatography technology	Chuang HC (2006), Chuang HC (2006)	2
HDAC1	4	PRDM1	5	affinity chromatography technology, affinity chromatography technology	Su ST (2009), Morgan MA (2012)	2
SUMO1	0	HIPK2	0	two hybrid, imaging technique, pull down	Lee BH (2003), de la Vega L (2011), de la Vega L (2011)	3
RANGAP1	4	RANBP2	9	pull down, pull down, x-ray crystallography, affinity chromatography technology, pull down, biochemical	Gilbreth RN (2011), Werner A (2012), Gareau JR (2012), Saitoh H (2002), Zhang H (2002), Wan C (2015)	6
BAG3	4	UBE2K	0	affinity chromatography technology	Chen Y (2013)	1
SP100	4	SUMO2	0	two hybrid, two hybrid, pull down	Wang J (2011), Hecker CM (2006), Hecker CM (2006)	3
NUP153	1	SENP1	0	affinity chromatography technology	Hein MY (2015)	1
RUVBL2	4	APP	1	pull down	Olah J (2011)	1
SUMO1	0	USP25	0	pull down, pull down, pull down	Meulmeester E (2008), Meulmeester E (2008), Yang Y (2017)	3
SENP1	0	BLK	4	affinity chromatography technology	Huttlin EL (2017)	1
KPNB1	3	RANGAP1	4	affinity chromatography technology	Hein MY (2015)	1
HDAC1	4	SENP1	0	affinity chromatography technology	Cheng J (2004)	1
NUP107	1	APC	5	bioid	Kim DI (2014)	1
RANBP2	9	SP100	4	enzymatic study, enzymatic study	Tatham MH (2005), Pichler A (2002)	2
HIPK2	0	SP100	4	affinity chromatography technology	Moeller A (2003)	1
LMNA	2	RANGAP1	4	bioid	Roux KJ (2012)	1
TP53	0	HNRNPL	3	affinity chromatography technology	Horikawa I (2014)	1
PHF12	6	HDAC2	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Varier RA (2016)	2
NUP107	1	SENP1	0	bioid	Kim DI (2014)	1
NUP43	0	SENP1	0	bioid	Kim DI (2014)	1
SUMO1	0	RANBP2	9	two hybrid, pull down, pull down, affinity chromatography technology	Hecker CM (2006), Martin SF (2008), Ullmann R (2012), Ullmann R (2012)	4
KPNB1	3	SUMO1	0	affinity chromatography technology	Hein MY (2015)	1
RANBP2	9	HDAC4	10	enzymatic study	Kirsh O (2002)	1
HDAC1	4	HDAC2	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology	Hakimi MA (2002), Yao YL (2003), Yao YL (2003), Hakimi MA (2003), Fischle W (2002), Johnson CA (2002), Fischle W (2001), Fischer DD (2002), Fischer DD (2002), Ashburner BP (2001), Zhang Y (1999), Tong JK (1998), Tong JK (1998), Hassig CA (1998), Hassig CA (1998), Zhang Y (1997), van der Vlag J (1999), van der Vlag J (1999), Noh EJ (2009), Noh EJ (2009), Galasinski SC (2002), Galasinski SC (2002), Galasinski SC (2002), He S (2005), Humphrey GW (2001), Park JH (2004), Park JH (2004), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Martinez FP (2012), Martinez FP (2012), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Joshi P (2013), Schnur N (2007), Schnur N (2007), Oh YM (2009), Wan C (2015), Hein MY (2015), Chen TC (2014), Huttlin EL (2017)	48
BAG3	4	RUVBL2	4	affinity chromatography technology, affinity chromatography technology	Chen Y (2013), Chen Y (2013)	2
ELAVL1	0	KPNB1	3	affinity chromatography technology	Abdelmohsen K (2009)	1
SP100	4	SUMO1	0	two hybrid, two hybrid, pull down, two hybrid	Rual JF (2005), Hecker CM (2006), Hecker CM (2006), Rolland T (2014)	4
LMNA	2	SCARA3	2	two hybrid	Dittmer TA (2014)	1
NUP107	1	SUMO1	0	affinity chromatography technology	Hein MY (2015)	1
SUMO1	0	RANGAP1	4	pull down	Tatham MH (2003)	1
SCARA3	2	SENP1	0	affinity chromatography technology	Huttlin EL (2015)	1
HDAC1	4	PML	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology	Khan MM (2001), Khan MM (2001), Wu WS (2001), Wu WS (2001), Wu WS (2001), Wu WS (2001), Wu WS (2001), Morey L (2008), Kuo HY (2013), Kim YE (2015)	10
HDAC4	10	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
SENP1	0	NACC1	9	enzymatic study	Tatemichi Y (2015)	1
SENP1	0	RABGAP1	2	enzymatic study	Gong L (2006)	1
EGLN3	0	RANGAP1	4	affinity chromatography technology	Rodriguez J (2016)	1
ELAVL1	0	PARP1	3	affinity chromatography technology	Abdelmohsen K (2009)	1
KPNB1	3	SENP1	0	affinity chromatography technology	Hein MY (2015)	1
SENP1	0	SENP1	0	affinity chromatography technology, pull down	Xu Z (2008), Xu Z (2008)	2
EGLN3	0	NUP43	0	affinity chromatography technology	Rodriguez J (2016)	1
SKP2	2	SENP1	0	affinity chromatography technology	Huttlin EL (2017)	1
SENP1	0	USP25	0	enzymatic study	Meulmeester E (2008)	1
SUMO1	0	TP53	0	two hybrid	Minty A (2000)	1
SKP2	2	SIRT6	2	pull down	Inuzuka H (2012)	1
APC	5	NUP153	1	two hybrid	Bandyopadhyay S (2010)	1
RANBP2	9	KPNB1	3	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Yaseen NR (1999), Delphin C (1997), Ben-Efraim I (2001), Walther TC (2003), Chi NC (1996), Chi NC (1996), Hein MY (2015)	7
SENP1	0	PRDM1	5	affinity chromatography technology	Shimshon L (2011)	1
SUMO2	0	HDAC2	1	pull down	Ouyang J (2009)	1
ELAVL1	0	PRDM1	5	affinity chromatography technology	Abdelmohsen K (2009)	1
NUP153	1	SUMO1	0	affinity chromatography technology	Hein MY (2015)	1
LRP1	25	APP	1	affinity chromatography technology	Lakshmana MK (2009)	1
SUMO3	0	USP25	0	pull down, pull down	Meulmeester E (2008), Meulmeester E (2008)	2
BAG3	4	RANBP2	9	affinity chromatography technology	Chen Y (2013)	1
PML	7	SUMO1	0	two hybrid, imaging technique, fluorescent resonance energy transfe, two hybrid, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down, x-ray crystallography, fluorescent resonance energy transfe, unspecified method, two hybrid, pull down	Lin DY (2002), Cuchet-Lourenco D (2011), Percherancier Y (2009), Cuchet-Lourenco D (2012), Stehmeier P (2009), Duprez E (1999), Shen TH (2006), Shen TH (2006), Saether T (2007), Cappadocia L (2015), Cappadocia L (2015), Cappadocia L (2015), Li C (2017), Li C (2017)	14
PML	7	SP100	4	imaging technique, imaging technique, imaging technique, imaging technique, two hybrid, imaging technique	Cuchet-Lourenco D (2011), Cuchet-Lourenco D (2011), Cuchet D (2011), Negorev D (2001), Sternsdorf T (1997), Sahin U (2014)	6
ISG15	0	HNRNPL	3	affinity chromatography technology	Zhao C (2005)	1
USP25	0	SUMO2	0	pull down, two hybrid, pull down	Meulmeester E (2008), Rolland T (2014), Yang Y (2017)	3
PROZ	0	SENP1	0	affinity chromatography technology	Huttlin EL (2017)	1
HNRNPL	3	HIPK2	0	affinity chromatography technology	Fei T (2017)	1
RUVBL2	4	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim JH (2006), Rashid S (2009), Lee JS (2010), Lee JS (2010), Lee JS (2010)	5
ARRB2	5	RANGAP1	4	affinity chromatography technology	Xiao K (2007)	1
TP53	0	LMNA	2	affinity chromatography technology	Horikawa I (2014)	1
BAG3	4	PARP1	3	affinity chromatography technology	Chen Y (2013)	1
HERC2	9	SENP1	0	affinity chromatography technology	Galligan JT (2015)	1
SUMO2	0	HDAC1	4	pull down	Ouyang J (2009)	1
EGLN3	0	NUP107	1	affinity chromatography technology	Rodriguez J (2016)	1
USP25	0	APP	1	affinity chromatography technology	Jung ES (2015)	1
RIPK4	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
PARP1	3	HDAC1	4	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Hassa PO (2005), Hassa PO (2005), Hang CT (2010), Rajamohan SB (2009)	4
SENP1	0	CAV3	0	enzymatic study	Fuhs SR (2011)	1
SUMO3	0	SP100	4	pull down	Hecker CM (2006)	1
TP53	0	HIPK2	0	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Hofmann TG (2002), Hofmann TG (2002), Hofmann TG (2002), Hofmann TG (2002), Kim EJ (2002), Sung KS (2005), Li Q (2011), Di Stefano V (2005), Rinaldo C (2007), Rinaldo C (2007), Lee MG (2014), Mancini F (2016)	12
SENP1	0	PML	7	enzymatic study	Galisson F (2011)	1
EGLN3	0	PML	7	affinity chromatography technology	Rodriguez J (2016)	1
PARP1	3	TP53	0	affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, pull down, pull down	Gueven N (2004), Malanga M (1998), Vaziri H (1997), Vaziri H (1997), Wesierska-Gadek J (2003), Simbulan-Rosenthal CM (2003)	6
HNRNPL	3	LRP1	25	affinity chromatography technology	Fei T (2017)	1
ELAVL1	0	HDAC2	1	affinity chromatography technology	Abdelmohsen K (2009)	1
HDAC2	1	PML	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wu WS (2001), Morey L (2008), Kraemer OH (2008), Kim YE (2015)	4
SUMO3	0	HIPK2	0	pull down	de la Vega L (2011)	1
SENP1	0	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
PML	7	NACC1	9	pull down	Tatemichi Y (2015)	1
ISG15	0	ELAVL1	0	affinity chromatography technology	Zhao C (2005)	1
TP53	0	PML	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Kurki S (2003), Kurki S (2003), Fogal V (2000), Fogal V (2000), Guo A (2000), Guo A (2000), Insinga A (2004), Chu Y (2011), Li Q (2011), Li Q (2011), Bernassola F (2005), Yang Q (2013), Yang Q (2013), Catalano A (2004), Chen TC (2014)	15
UBE2K	0	TP53	0	affinity chromatography technology, affinity chromatography technology, protein complementation assay	Bae Y (2013), Bae Y (2013), Bae Y (2013)	3
ELAVL1	0	RABGAP1	2	affinity chromatography technology	Abdelmohsen K (2009)	1
ARRB2	5	KPNB1	3	affinity chromatography technology	Xiao K (2007)	1
SENP1	0	PARP1	3	enzymatic study	Messner S (2009)	1
SENP1	0	ARRB2	5	affinity chromatography technology	Xiao N (2015)	1
LMNA	2	RANBP2	9	bioid	Roux KJ (2012)	1
ELAVL1	0	SENP1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
HNRNPL	3	UBE2K	0	affinity chromatography technology	Fei T (2017)	1
LMNA	2	PML	7	bioid	Roux KJ (2012)	1
HERC2	9	LMNA	2	affinity chromatography technology	Galligan JT (2015)	1
RUVBL2	4	HDAC2	1	affinity chromatography technology	Rashid S (2009)	1
ELAVL1	0	SKP2	2	affinity chromatography technology	Abdelmohsen K (2009)	1
SUMO2	0	RANBP2	9	two hybrid	Hecker CM (2006)	1
LMNA	2	ELAVL1	0	affinity chromatography technology	Depreux FF (2015)	1
EGLN3	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
HIPK2	0	PML	7	affinity chromatography technology, enzymatic study, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study	de la Vega L (2011), Renner F (2010), Sung KS (2011), Sung KS (2011), Gresko E (2009), Gresko E (2009), Gresko E (2009)	7
EGLN3	0	APC	5	affinity chromatography technology	Rodriguez J (2016)	1
KPNB1	3	NUP43	0	affinity chromatography technology	Hein MY (2015)	1
HIPK2	0	PARP1	3	affinity chromatography technology, pull down, affinity chromatography technology	Choi JR (2016), Choi JR (2016), Choi JR (2016)	3
NUP107	1	RANGAP1	4	bioid, affinity chromatography technology	Kim DI (2014), Hein MY (2015)	2
SENP1	0	HIPK2	0	enzymatic study	Kim YH (2005)	1
HERC2	9	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Cubillos-Rojas M (2014), Cubillos-Rojas M (2014), Cubillos-Rojas M (2014), Bai B (2016)	4
TRMT1	3	SENP1	0	affinity chromatography technology	Huttlin EL (2017)	1
SENP1	0	RUVBL2	4	affinity chromatography technology, affinity chromatography technology	Kim JH (2006), Lee JS (2010)	2
GCM1	2	SENP1	0	affinity chromatography technology, affinity chromatography technology, pull down	Chang CW (2011), Chang CW (2011), Chang CW (2011)	3
PHF12	6	SENP1	0	affinity chromatography technology	Varier RA (2016)	1
ARL11	0	SENP1	0	affinity chromatography technology	Huttlin EL (2017)	1
PRDM1	5	HDAC2	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu J (2000), Yu J (2000), Gyoery I (2003), Su ST (2009), Ying HY (2012), Morgan MA (2012)	6
RANBP2	9	TP53	0	enzymatic study	Gareau JR (2012)	1
ELAVL1	0	SUMO2	0	affinity chromatography technology	Abdelmohsen K (2009)	1
ELAVL1	0	HNRNPL	3	affinity chromatography technology	Abdelmohsen K (2009)	1
TP53	0	KPNB1	3	affinity chromatography technology, pull down	Akakura S (2001), Akakura S (2001)	2
IL13RA2	0	SENP1	0	affinity chromatography technology	Huttlin EL (2017)	1
SUMO3	0	PML	7	imaging technique	Cuchet-Lourenco D (2011)	1
NUP107	1	KPNB1	3	affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Walther TC (2003), Kim DI (2014), Hein MY (2015), Hein MY (2015)	4
SENP1	0	RANGAP1	4	x-ray crystallography, fluorescent resonance energy transfe, pull down, enzymatic study, enzymatic study	Shen L (2006), Shen L (2006), Shen L (2006), Wen D (2014), Shen LN (2006)	5
HERC2	9	NUP153	1	affinity chromatography technology	Galligan JT (2015)	1
GCM1	2	HDAC4	10	affinity chromatography technology, affinity chromatography technology	Chuang HC (2006), Chuang HC (2006)	2
SIRT6	2	SENP1	0	affinity chromatography technology	Huttlin EL (2017)	1
EGLN3	0	KPNB1	3	affinity chromatography technology	Rodriguez J (2016)	1
SENP1	0	UBE2K	0	enzymatic study	Galisson F (2011)	1
NUP43	0	NUP153	1	bioid, affinity chromatography technology	Kim DI (2014), Hein MY (2015)	2
ARRB2	5	HDAC2	1	affinity chromatography technology	Xiao K (2007)	1
ELAVL1	0	HDAC4	10	affinity chromatography technology	Abdelmohsen K (2009)	1
TP53	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique	Ito A (2002), Wang C (2005), Dohi Y (2008), Jin W (2008), Lei Q (2006), Wu Y (2001), Wu Y (2001), Luo J (2000), Juan LJ (2000), Juan LJ (2000), Juan LJ (2000), Murphy M (1999), Insinga A (2004), Sun JM (2007), Yu XY (2010), Sinha S (2010), Sinha S (2010), Li Y (2012), Di Agostino S (2006), Pavithra L (2009), Pavithra L (2009), Luo J (2000), Chen TC (2014), Park EK (2015), Park EK (2015), Park EK (2015)	26
EGLN3	0	NUP153	1	affinity chromatography technology	Rodriguez J (2016)	1
PML	7	RANBP2	9	affinity chromatography technology	Satow R (2012)	1
ISG15	0	SENP1	0	affinity chromatography technology	Zhao C (2005)	1
SIRT6	2	LMNA	2	affinity chromatography technology	Simeoni F (2013)	1
RUVBL2	4	KPNB1	3	affinity chromatography technology	Jeronimo C (2007)	1
HNRNPL	3	RABGAP1	2	affinity chromatography technology	Fei T (2017)	1
SIRT6	2	HDAC2	1	affinity chromatography technology	Simeoni F (2013)	1
HDAC4	10	SENP1	0	imaging technique	Maciejewska-Rodrigues H (2010)	1
LMNA	2	PARP1	3	bioid, affinity chromatography technology	Roux KJ (2012), Depreux FF (2015)	2
TP53	0	HDAC2	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li P (2010), Insinga A (2004), Sun JM (2007), Tian B (2011), Adenuga D (2010), Brandl A (2012)	6
NUP43	0	RANBP2	9	bioid	Kim DI (2014)	1
ISG15	0	NUP43	0	affinity chromatography technology	Zhao C (2005)	1
EGLN3	0	RANBP2	9	affinity chromatography technology	Rodriguez J (2016)	1
SIRT6	2	HDAC1	4	affinity chromatography technology	Simeoni F (2013)	1
EGLN3	0	SENP1	0	affinity chromatography technology	Rodriguez J (2016)	1
SUMO2	0	HIPK2	0	pull down	de la Vega L (2011)	1
PARP1	3	HDAC2	1	affinity chromatography technology, pull down, affinity chromatography technology	Hassa PO (2005), Hassa PO (2005), Hang CT (2010)	3
BAG3	4	SENP1	0	affinity chromatography technology	Chen Y (2013)	1
LMNA	2	HNRNPL	3	affinity chromatography technology	Depreux FF (2015)	1
HNRNPL	3	HDAC4	10	affinity chromatography technology	Fei T (2017)	1
SENP1	0	SUMO2	0	fluorescent resonance energy transfe, pull down, x-ray crystallography, enzymatic study, pull down, enzymatic study, enzymatic study	Shen L (2006), Shen L (2006), Shen LN (2006), Shen LN (2006), Shen LN (2006), Mukhopadhyay D (2006), Schulz S (2012)	7
APC	5	SENP1	0	affinity chromatography technology	Hein MY (2015)	1
NUP107	1	RANBP2	9	bioid, affinity chromatography technology	Kim DI (2014), Hein MY (2015)	2
SENP1	0	SUMO3	0	enzymatic study, enzymatic study, pull down, enzymatic study	Shen LN (2006), Gong L (2006), Schulz S (2012), Schulz S (2012)	4
F9	0	LRP1	25	pull down	Rohlena J (2003)	1
APC	5	RANBP2	9	two hybrid, affinity chromatography technology, affinity chromatography technology	Bandyopadhyay S (2010), Murawala P (2009), Novellasdemunt L (2017)	3
ISG15	0	LMNA	2	affinity chromatography technology	Zhao C (2005)	1
LMNA	2	NUP153	1	bioid, bioid	Roux KJ (2012), Kim DI (2014)	2
SIRT6	2	RUVBL2	4	affinity chromatography technology	Simeoni F (2013)	1
ZNF420	4	TP53	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tian C (2009), Tian C (2009), Tian C (2009), Tian C (2009), Wang S (2010), Wang S (2010)	6
HNRNPL	3	SENP1	0	affinity chromatography technology	Fei T (2017)	1
NUP153	1	SUMO2	0	affinity chromatography technology	Hein MY (2015)	1
BAG3	4	ISG15	0	affinity chromatography technology, affinity chromatography technology	Chen Y (2013), Chen Y (2013)	2
NUP107	1	NUP153	1	biochemical, biochemical, bioid, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Kim DI (2014), Hein MY (2015), Hein MY (2015)	5
SENP1	0	RANBP2	9	enzymatic study	Gareau JR (2012)	1
F9	0	SENP1	0	affinity chromatography technology	Huttlin EL (2017)	1
RIPK4	0	SENP1	0	affinity chromatography technology	Rodriguez J (2016)	1
HDAC2	1	SENP1	0	affinity chromatography technology	Brandl A (2012)	1
NUP43	0	NUP107	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Loiodice I (2004), Kaur S (2010), Glavy JS (2007), Huttlin EL (2015), Kim DI (2014), Hein MY (2015), Huttlin EL (2017)	7
SENP1	0	SP100	4	enzymatic study	Schulz S (2012)	1
SENP1	0	SUMO1	0	x-ray crystallography, fluorescent resonance energy transfe, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study	Shen L (2006), Shen L (2006), Shen L (2006), Shen LN (2006), Mukhopadhyay D (2006), Gong L (2006), Schulz S (2012), Schulz S (2012)	8
RANBP2	9	NUP153	1	affinity chromatography technology, affinity chromatography technology	Yokoyama N (1995), Hein MY (2015)	2
SUMO2	0	PML	7	imaging technique, two hybrid, pull down	Cuchet-Lourenco D (2011), Li C (2017), Li C (2017)	3
SENP1	0	ZNF420	4	affinity chromatography technology, pull down, affinity chromatography technology	Wang S (2015), Wang S (2015), Wang S (2015)	3
PHF12	6	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yochum GS (2001), Joshi P (2013), Hein MY (2015), Hein MY (2015), Varier RA (2016), Huttlin EL (2017)	6
HNRNPL	3	ARRB2	5	affinity chromatography technology	Fei T (2017)	1
NACC1	9	HDAC4	10	two hybrid, pull down, affinity chromatography technology, pull down	Korutla L (2005), Korutla L (2005), Korutla L (2005), Korutla L (2005)	4
LRP1	25	SENP1	0	affinity chromatography technology	Huttlin EL (2017)	1