PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
ANAPC7	2	EP300	36	affinity chromatography technology, affinity chromatography technology	Turnell AS (2005), Turnell AS (2005)	2
CDC5L	2	PRKDC	12	affinity chromatography technology, biochemical, affinity chromatography technology	Ajuh P (2000), Ajuh P (2000), Lleres D (2010)	3
ANAPC11	0	UBE2S	2	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Huang NJ (2012), Wang W (2013), Frye JJ (2013), Chang L (2014), Brown NG (2014), Wu T (2010), Sedgwick GG (2013), Fukushima H (2013), Yamaguchi M (2015), Brown NG (2015), Brown NG (2014), Kelly A (2014), Kelly A (2014), Craney A (2016), Zhang S (2016), Williamson A (2011), Qiao R (2016), Brown NG (2016), Li Q (2016)	19
NINL	1	CDC20	1	affinity chromatography technology, affinity chromatography technology	Wang Y (2007), Wang Y (2007)	2
SMAD2	5	CDC16	2	affinity chromatography technology	Stroschein SL (2001)	1
CDC27	2	CDC26	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Gmachl M (2000), Kraft C (2003), Dube P (2005), Holzmann J (2011), Gmachl M (2000), Vodermaier HC (2003), Vodermaier HC (2003), Masuda K (2015)	8
ANAPC13	0	CDC16	2	biochemical, biochemical, affinity chromatography technology, genetic interference	Havugimana PC (2012), Wan C (2015), Huttlin EL (2017), Horlbeck MA (2018)	4
ANAPC13	0	CDC26	0	biochemical, affinity chromatography technology, genetic interference	Havugimana PC (2012), Huttlin EL (2017), Horlbeck MA (2018)	3
ANAPC4	0	ANAPC5	2	biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015)	8
ANAPC2	0	ANAPC10	0	biochemical, affinity chromatography technology, biochemical	Havugimana PC (2012), Vodermaier HC (2003), Wan C (2015)	3
LATS2	1	CDC23	3	affinity chromatography technology, affinity chromatography technology	Zhu C (2018), Zhu C (2018)	2
EP300	36	MDC1	8	affinity chromatography technology	Jung SY (2005)	1
ANAPC5	2	CDC16	2	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	4
ANAPC1	1	ANAPC5	2	biochemical, biochemical, affinity chromatography technology, biochemical	Sumara I (2000), Havugimana PC (2012), Vodermaier HC (2003), Wan C (2015)	4
MAGIX	0	ANAPC4	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MAD2L1	0	ANAPC2	0	affinity chromatography technology	Zhang Y (2001)	1
FZR1	1	CDC26	0	pull down, unspecified method, biochemical, affinity chromatography technology	Vodermaier HC (2003), Vodermaier HC (2003), Masuda K (2015), Huttlin EL (2017)	4
MDC1	8	ANAPC7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Townsend K (2009), Townsend K (2009), Woods NT (2012)	3
CDC20	1	ANAPC1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nilsson J (2008), Hein JB (2014), Lischetti T (2014), Kelly A (2014), Craney A (2016), Qiao R (2016), Qiao R (2016), Hein JB (2016)	8
ANAPC10	0	ANAPC1	1	biochemical	Havugimana PC (2012)	1
UBE2S	2	CDC16	2	pull down	Brown NG (2014)	1
ANAPC2	0	CREBBP	29	affinity chromatography technology	Turnell AS (2005)	1
UBE2S	2	CDC20	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Williamson A (2009), Williamson A (2009), Brown NG (2014), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016)	7
MDC1	8	ANAPC1	1	affinity chromatography technology, pull down, affinity chromatography technology	Coster G (2007), Townsend K (2009), Woods NT (2012)	3
CDC5L	2	CDC16	2	affinity chromatography technology	Lleres D (2010)	1
ANAPC15	0	FBXO5	2	affinity chromatography technology	Hein MY (2015)	1
TP53BP1	3	CDC23	3	affinity chromatography technology	Woods NT (2012)	1
RNF34	1	ANAPC2	0	affinity chromatography technology, affinity chromatography technology	Puliyappadamba VT (2011), Puliyappadamba VT (2011)	2
FBXO5	2	ANAPC4	0	pull down, biochemical, affinity chromatography technology	Miller JJ (2006), Chang L (2015), Voets E (2015)	3
CDC27	2	CDC23	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Lara-Gonzalez P (2011), Tran K (2008), Dube P (2005), Fehr AR (2012), Holzmann J (2011), Lee SJ (2012), Hayes MJ (2006), Havugimana PC (2012), Vodermaier HC (2003), Tran K (2010), Wan C (2015), Hein MY (2015), Qiao R (2016), Qiao R (2016), Boldt K (2016)	18
MDM2	2	ANAPC2	0	affinity chromatography technology, affinity chromatography technology	He Y (2014), He Y (2014)	2
BUB1B	0	CDC16	2	affinity chromatography technology, affinity chromatography technology	Chan GK (1999), Tipton AR (2013)	2
TTLL1	4	ANAPC1	1	affinity chromatography technology	Huttlin EL (2015)	1
MDC1	8	CDC16	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Coster G (2007), Coster G (2007), Townsend K (2009), Townsend K (2009), Woods NT (2012)	5
ANAPC11	0	UBE2D2	0	affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Chang TS (2004), Townsend K (2009), Van Voorhis VA (2014), ODonovan KJ (2010), Tang Z (2001), Tang Z (2001), Vodermaier HC (2003), Shoji S (2014), Brown NG (2014), Brown NG (2015)	10
CDC27	2	ANAPC5	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Koloteva-Levine N (2004), Gmachl M (2000), Kraft C (2003), Lara-Gonzalez P (2011), Dube P (2005), Fehr AR (2012), Holzmann J (2011), Havugimana PC (2012), Song MS (2011), Vodermaier HC (2003), Tran K (2010), Kelly A (2014), Craney A (2016), Qiao R (2016)	15
CDC20	1	CREBBP	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Turnell AS (2005), Turnell AS (2005), Townsend K (2009)	3
CDC20	1	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	DAngiolella V (2003), Kallio MJ (2002), Wassmann K (1998), Kramer ER (1998), Kallio M (1998), Kallio M (1998), Nilsson J (2008), Jeganathan KB (2006), Nath S (2011), Lee YJ (2008), Lara-Gonzalez P (2011), Mansfeld J (2011), Braunstein I (2007), Visconti R (2010), Ma HT (2011), Lee YJ (2008), DAngiolella V (2003), Lee SJ (2012), Fang G (1998), Fang G (1998), Wolthuis R (2008), Ban KH (2007), Ge S (2009), Tipton AR (2011), Westhorpe FG (2011), Uzunova K (2012), Kwan PS (2013), Sedgwick GG (2012), Eytan E (2013), Hyun SY (2013), Lim HJ (2013), Choi BH (2014), Fogeron ML (2013), Sackton KL (2014), Shoji S (2014), Han JS (2014), Lara-Gonzalez P (2011), Hein JB (2014), Vodermaier HC (2003), Yen AH (2010), Voets E (2015), Boekhout M (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Craney A (2016), Listovsky T (2013), Qiao R (2016), Qiao R (2016), Qiao R (2016), Qiao R (2016), Qiao R (2016), Hein JB (2016)	54
MDC1	8	ANAPC2	0	affinity chromatography technology	Woods NT (2012)	1
ANAPC2	0	ANAPC7	2	biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Gmachl M (2000), Vodermaier HC (2003)	3
HSP90AA1	7	PRKDC	12	affinity chromatography technology	Falsone SF (2005)	1
UBE2S	2	CREBBP	29	biochemical	Wan C (2015)	1
TP53BP1	3	COPS5	0	two hybrid, affinity chromatography technology	Kwak HJ (2005), Kwak HJ (2005)	2
ANAPC13	0	ANAPC1	1	affinity chromatography technology	Huttlin EL (2017)	1
CDC5L	2	BUB1B	0	affinity chromatography technology	Lleres D (2010)	1
GRAP2	0	ANAPC1	1	affinity chromatography technology	Huttlin EL (2015)	1
NINL	1	CDC27	2	affinity chromatography technology	Wang Y (2007)	1
CDC26	0	CDC16	2	pull down, x-ray crystallography, two hybrid, two hybrid, biochemical, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology	Wang J (2009), Wang J (2009), Wang J (2011), Rolland T (2014), Wan C (2015), Yu H (2011), Hein MY (2015), Masuda K (2015), Masuda K (2015), Masuda K (2015), Huttlin EL (2017)	11
CDC27	2	ANAPC15	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Uzunova K (2012), Hein MY (2015)	3
TTLL1	4	CDC23	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ANAPC4	0	CDC26	0	biochemical, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang Z (2012), Chang L (2014), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Masuda K (2015)	6
CDC27	2	ANAPC2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kraft C (2003), Lara-Gonzalez P (2011), Dube P (2005), Dube P (2005), Holzmann J (2011), Lee SJ (2012), Hayes MJ (2006), Havugimana PC (2012), Gmachl M (2000), Cotto-Rios XM (2011), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Gmachl M (2000), Kelly A (2014), Craney A (2016), Qiao R (2016)	17
TP53BP1	3	ANAPC1	1	affinity chromatography technology	Woods NT (2012)	1
CDC16	2	ANAPC7	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hutchins JR (2010), Havugimana PC (2012), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	5
ANAPC15	0	FZR1	1	affinity chromatography technology	Hein MY (2015)	1
PHF8	6	CDC26	0	affinity chromatography technology	Lim HJ (2013)	1
MDC1	8	CDC27	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Coster G (2007), Coster G (2007), Townsend K (2009), Townsend K (2009), Townsend K (2009), Coster G (2012)	6
SOX2	4	ANAPC4	0	affinity chromatography technology	Cox JL (2013)	1
CREBBP	29	MDC1	8	affinity chromatography technology, affinity chromatography technology, pull down	Townsend K (2009), Townsend K (2009), Townsend K (2009)	3
ANAPC2	0	UBE2D2	0	pull down	Vodermaier HC (2003)	1
HSP90AA1	7	FZR1	1	genetic interference	Srivas R (2016)	1
FBXO5	2	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Moshe Y (2011), Miller JJ (2006), Miller JJ (2006), Miller JJ (2006), Miller JJ (2006), Huttlin EL (2017)	6
CDC27	2	ANAPC1	1	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Sumara I (2000), Lara-Gonzalez P (2011), Tran K (2008), Dube P (2005), Holzmann J (2011), Havugimana PC (2012), Vodermaier HC (2003), Tran K (2010), Wan C (2015), Qiao R (2016), Qiao R (2016)	12
ANAPC10	0	ANAPC7	2	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
MAGIX	0	CDC23	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FZR1	1	GRIA1	5	affinity chromatography technology	Fu AK (2011)	1
CDC20	1	ANAPC5	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sedgwick GG (2012), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Qiao R (2016)	6
LATS2	1	ANAPC2	0	affinity chromatography technology	Zhu C (2018)	1
ANAPC13	0	FZR1	1	affinity chromatography technology	Huttlin EL (2017)	1
MDC1	8	MDM2	2	unspecified method, affinity chromatography technology	Rodriguez M (2003), Inoue K (2008)	2
CDC20	1	ANAPC2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Stewart S (2005), Jia L (2011), Zhang Y (2001), Fogeron ML (2013), Lee SB (2015), Kelly A (2014), Craney A (2016), Qiao R (2016), Qiao R (2016)	9
CDC16	2	EP300	36	affinity chromatography technology	Turnell AS (2005)	1
FZR1	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
LATS2	1	CDC16	2	affinity chromatography technology	Zhu C (2018)	1
C16orf87	0	ANAPC7	2	affinity chromatography technology	Huttlin EL (2017)	1
CREBBP	29	ANAPC5	2	affinity chromatography technology, pull down	Turnell AS (2005), Turnell AS (2005)	2
HSP90AA1	7	EPHA4	3	affinity chromatography technology	Taipale M (2012)	1
EPHA4	3	ANAPC2	0	affinity chromatography technology, affinity chromatography technology	Fu AK (2011), Fu AK (2011)	2
CDC20	1	ANAPC10	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nilsson J (2008), Voets E (2015), Kelly A (2014), Craney A (2016)	4
SMAD2	5	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MDC1	8	PRKDC	12	pull down, affinity chromatography technology, imaging technique, affinity chromatography technology	Lou Z (2004), Lou Z (2004), Lou Z (2004), Lou Z (2004)	4
CDC20	1	BUB1B	0	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Fang G (2002), Fang G (2002), Wu H (2000), Wu H (2000), Wu H (2000), Kallio MJ (2002), Sudakin V (2001), Sudakin V (2001), Skoufias DA (2001), Nilsson J (2008), Ho CY (2010), Ho CY (2010), Garnett MJ (2009), Hutchins JR (2010), Di Fiore B (2010), Di Fiore B (2010), Mansfeld J (2011), Jia L (2011), Braunstein I (2007), Eytan E (2008), Eytan E (2008), Ma HT (2011), Miniowitz-Shemtov S (2012), Tang Z (2001), Tang Z (2001), Tang Z (2001), Tang Z (2001), Bolanos-Garcia VM (2011), Ge S (2009), Liu L (2007), Westhorpe FG (2011), Westhorpe FG (2011), Kwan PS (2013), Tian W (2012), Tian W (2012), Tian W (2012), Santaguida S (2011), Hyun SY (2013), Han JS (2013), Rodriguez-Bravo V (2014), Fogeron ML (2013), Wang K (2014), Han JS (2014), Izawa D (2014), Hein JB (2014), So J (2015), Scialpi F (2015), Scialpi F (2015), Diaz-Martinez LA (2015), Diaz-Martinez LA (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Voets E (2015), Chen TC (2014), Lischetti T (2014), Lischetti T (2014), Lischetti T (2014), Tipton AR (2013), Boekhout M (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Sedgwick GG (2016), Qiao R (2016), Huttlin EL (2017), Izawa D (2012), Jia L (2016), Jia L (2016), Hein JB (2016), Kaisari S (2017)	73
ANAPC1	1	CDC26	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
CDC20	1	CDC16	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kallio MJ (2002), Kallio M (1998), Nilsson J (2008), Hutchins JR (2010), Fogeron ML (2013), Hein JB (2014), Hein MY (2015), Kelly A (2014), Craney A (2016), Listovsky T (2013), Qiao R (2016), Izawa D (2012)	12
ANAPC10	0	ANAPC4	0	biochemical, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Voets E (2015)	8
UBE2S	2	ANAPC7	2	pull down	Brown NG (2014)	1
CDC20	1	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Turnell AS (2005), Turnell AS (2005), Huttlin EL (2017)	3
RB1	2	CDC27	2	affinity chromatography technology, biochemical, two hybrid, pull down	Binne UK (2007), Binne UK (2007), Chen PL (1995), Chen PL (1995)	4
TTLL1	4	ANAPC5	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FBXO5	2	CDC16	2	affinity chromatography technology, pull down, affinity chromatography technology	Miller JJ (2006), Miller JJ (2006), Hein MY (2015)	3
CREBBP	29	MDM2	2	affinity chromatography technology, enzymatic study, affinity chromatography technology	Inoue Y (2011), Wang X (2004), Sanchez M (2012)	3
MAGIX	0	CDC27	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FZR1	1	PTTG1	0	affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Pfleger CM (2001), Jin L (2008), Tian W (2012), He J (2013), Wang W (2013), Van Voorhis VA (2014), Gmachl M (2000), Wu T (2010), Vodermaier HC (2003), Jeganathan KB (2006), Yamaguchi M (2015), Brown NG (2015), Williamson A (2011), Qiao R (2016), Brown NG (2016)	15
MDC1	8	CDC20	1	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Townsend K (2009), Townsend K (2009), Townsend K (2009), Townsend K (2009), Woods NT (2012)	5
ANAPC1	1	CDC23	3	biochemical, biochemical, affinity chromatography technology	Sumara I (2000), Havugimana PC (2012), Hein MY (2015)	3
CDC23	3	CDC26	0	affinity chromatography technology	Hein MY (2015)	1
MAGIX	0	ANAPC2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ANAPC13	0	ANAPC5	2	biochemical, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2017)	2
COPS5	0	MDM2	2	affinity chromatography technology, pull down	Zhang XC (2008), Zhang XC (2008)	2
FBXO2	0	ANAPC2	0	affinity chromatography technology	Wen H (2010)	1
IST1	0	ANAPC2	0	affinity chromatography technology	Zhang X (2011)	1
CDC5L	2	ANAPC7	2	affinity chromatography technology	Lleres D (2010)	1
ANAPC2	0	ANAPC4	0	biochemical, biochemical, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Gmachl M (2000), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Boekhout M (2015)	11
CREBBP	29	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nath S (2011), Nath S (2011), Townsend K (2009)	3
CDC20	1	ANAPC4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Mansfeld J (2011), Mansfeld J (2011), Izawa D (2011), Ma HT (2011), Wolthuis R (2008), Sedgwick GG (2012), Zhang Z (2012), Chang L (2014), Fogeron ML (2013), Hein JB (2014), Hein JB (2014), Voets E (2015), Voets E (2015), Tipton AR (2013), Boekhout M (2015), Kelly A (2014), Craney A (2016), Craney A (2016), Sedgwick GG (2016), Qiao R (2016), Izawa D (2012), Izawa D (2012), Izawa D (2012), Izawa D (2012), Salsi V (2016)	25
UBE2S	2	ANAPC5	2	pull down	Brown NG (2014)	1
FZR1	1	ANAPC10	0	unspecified method	Vodermaier HC (2003)	1
CDC16	2	CDC23	3	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	6
COPS5	0	CDC20	1	affinity chromatography technology	Bennett EJ (2010)	1
MDC1	8	COPS5	0	two hybrid	Woods NT (2012)	1
SMARCAD1	1	ANAPC2	0	affinity chromatography technology	Rowbotham SP (2011)	1
ZNF408	0	CDC16	2	affinity chromatography technology	Huttlin EL (2017)	1
GRAP2	0	ANAPC7	2	affinity chromatography technology	Huttlin EL (2015)	1
PHF8	6	ANAPC1	1	affinity chromatography technology	Lim HJ (2013)	1
ANAPC15	0	ANAPC13	0	affinity chromatography technology	Hein MY (2015)	1
FBXO5	2	CDC23	3	pull down, affinity chromatography technology	Miller JJ (2006), Hein MY (2015)	2
EP300	36	PRKDC	12	pull down	Karmakar S (2010)	1
CDC27	2	ANAPC10	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Lara-Gonzalez P (2011), Dube P (2005), Fehr AR (2012), Holzmann J (2011), Kurasawa Y (1999), Kurasawa Y (1999), Havugimana PC (2012), Vodermaier HC (2003), Wan C (2015), Hein MY (2015)	13
C16orf87	0	ANAPC2	0	affinity chromatography technology	Huttlin EL (2017)	1
FBXO5	2	ANAPC11	0	pull down	Miller JJ (2006)	1
PHF8	6	CDC23	3	affinity chromatography technology	Lim HJ (2013)	1
MAGIX	0	ANAPC7	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PHF8	6	CDC16	2	affinity chromatography technology	Lim HJ (2013)	1
TTLL1	4	ANAPC2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ANAPC15	0	CDC26	0	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
SMARCAD1	1	CDC27	2	affinity chromatography technology	Rowbotham SP (2011)	1
TP53BP1	3	ANAPC4	0	affinity chromatography technology	Woods NT (2012)	1
BUB1B	0	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chan GK (1999), Hutchins JR (2010), Lara-Gonzalez P (2011), Mansfeld J (2011), Tipton AR (2011), Westhorpe FG (2011), Uzunova K (2012), Eytan E (2013), Wang K (2014), Han JS (2014), Han JS (2014), Lara-Gonzalez P (2011), So J (2015), Boekhout M (2015), Kelly A (2014), Craney A (2016), Qiao R (2016)	17
ANAPC13	0	BUB1B	0	genetic interference	Horlbeck MA (2018)	1
C16orf87	0	FZR1	1	affinity chromatography technology	Huttlin EL (2017)	1
ANAPC1	1	ANAPC2	0	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Sumara I (2000), Havugimana PC (2012), Gmachl M (2000), Vodermaier HC (2003)	4
C16orf87	0	ANAPC5	2	affinity chromatography technology	Huttlin EL (2017)	1
LATS2	1	NINL	1	bioid	Couzens AL (2013)	1
MAGIX	0	ANAPC5	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ANAPC13	0	FBXO5	2	affinity chromatography technology	Huttlin EL (2017)	1
UBE2C	1	MAD2L1	0	biochemical	Reddy SK (2007)	1
BUB1B	0	MDM2	2	affinity chromatography technology	Miniowitz-Shemtov S (2012)	1
PHF8	6	ANAPC7	2	affinity chromatography technology	Lim HJ (2013)	1
CDC23	3	BUB1B	0	affinity chromatography technology	Hein MY (2015)	1
ANAPC13	0	ANAPC4	0	biochemical, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Chang L (2015), Yamaguchi M (2015), Huttlin EL (2017)	6
CDC5L	2	UBE2S	2	affinity chromatography technology	Lleres D (2010)	1
RB1	2	FZR1	1	affinity chromatography technology, biochemical	Binne UK (2007), Binne UK (2007)	2
ANAPC4	0	MAD2L1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mansfeld J (2011), Ma HT (2011), Sedgwick GG (2012), Voets E (2015), Tipton AR (2013), Boekhout M (2015), Sedgwick GG (2016), Izawa D (2012), Salsi V (2016)	9
ANAPC2	0	CDC26	0	affinity chromatography technology, affinity chromatography technology	Gmachl M (2000), Vodermaier HC (2003)	2
SOX2	4	ANAPC1	1	affinity chromatography technology	Cox JL (2013)	1
C16orf87	0	CDC23	3	affinity chromatography technology	Huttlin EL (2017)	1
FZR1	1	ANAPC1	1	pull down, unspecified method, affinity chromatography technology	Vodermaier HC (2003), Vodermaier HC (2003), Huttlin EL (2017)	3
ANAPC15	0	ANAPC5	2	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
BUB1B	0	MAD2L1	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sudakin V (2001), Sudakin V (2001), Ho CY (2010), Bolanos-Garcia VM (2011), Tipton AR (2011), Tipton AR (2011), Tipton AR (2011), Westhorpe FG (2011), Eytan E (2013), Han JS (2013), Wang K (2014), Wang K (2014), So J (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Lischetti T (2014), Tipton AR (2013), Tipton AR (2013), Boekhout M (2015), Sedgwick GG (2016), Sedgwick GG (2016), Sedgwick GG (2016)	23
ANAPC1	1	ANAPC7	2	biochemical, biochemical, biochemical	Sumara I (2000), Havugimana PC (2012), Wan C (2015)	3
SMAD2	5	ANAPC2	0	two hybrid	Colland F (2004)	1
PTTG1	0	CDC27	2	affinity chromatography technology, pull down, pull down	Jeganathan KB (2006), Miller JJ (2006), Qiao R (2016)	3
ANAPC15	0	CDC20	1	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
ANAPC15	0	CDC16	2	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
SOX2	4	CDC23	3	affinity chromatography technology	Cox JL (2013)	1
BUB1B	0	ANAPC1	1	affinity chromatography technology, affinity chromatography technology	So J (2015), Lischetti T (2014)	2
ANAPC4	0	CDC16	2	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mansfeld J (2011), Ma HT (2011), Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Hein MY (2015), Masuda K (2015), Boekhout M (2015), Huttlin EL (2017)	14
ANAPC13	0	ANAPC2	0	affinity chromatography technology	Huttlin EL (2017)	1
ANAPC2	0	CDC23	3	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Gmachl M (2000), Vodermaier HC (2003), Hein MY (2015)	4
ZNF408	0	CDC27	2	affinity chromatography technology	Huttlin EL (2017)	1
ANAPC11	0	ANAPC2	0	pull down, pull down, two hybrid, biochemical, affinity chromatography technology	Tang Z (2001), Tang Z (2001), Ohta T (1999), Lu L (2013), Vodermaier HC (2003)	5
HSP90AA1	7	ANAPC2	0	affinity chromatography technology	Taipale M (2012)	1
C16orf87	0	ANAPC1	1	affinity chromatography technology	Huttlin EL (2017)	1
ZNF408	0	CDC23	3	affinity chromatography technology	Huttlin EL (2017)	1
ANAPC15	0	CDC23	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015), Hein MY (2015)	3
ANAPC2	0	GRIA1	5	affinity chromatography technology	Fu AK (2011)	1
PTTG1	0	BUB1B	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology, genetic interference	Kim HS (2009), Kim HS (2009), Kim HS (2009), Kim HS (2009), Horlbeck MA (2018)	5
SMAD2	5	COPS5	0	two hybrid	Colland F (2004)	1
LATS2	1	ANAPC1	1	affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Couzens AL (2013), Couzens AL (2013), Zhu C (2018), Zhu C (2018), Zhu C (2018), Zhu C (2018)	6
CDC5L	2	COPS5	0	affinity chromatography technology	Lleres D (2010)	1
EP300	36	ANAPC5	2	affinity chromatography technology	Turnell AS (2005)	1
SMARCAD1	1	ANAPC1	1	affinity chromatography technology	Rowbotham SP (2011)	1
TP53BP1	3	ANAPC5	2	affinity chromatography technology	Woods NT (2012)	1
MDC1	8	CDC23	3	affinity chromatography technology	Woods NT (2012)	1
GRAP2	0	CDC27	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NINL	1	FZR1	1	affinity chromatography technology, affinity chromatography technology	Wang Y (2007), Wang Y (2007)	2
SOX2	4	ANAPC5	2	affinity chromatography technology	Cox JL (2013)	1
CDC20	1	CDC23	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nilsson J (2008), Fogeron ML (2013), Hein JB (2014), Hein MY (2015), Kelly A (2014), Craney A (2016), Qiao R (2016), Qiao R (2016)	8
MDC1	8	TP53BP1	3	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, imaging technique, affinity chromatography technology	Eliezer Y (2009), Eliezer Y (2009), Eliezer Y (2009), Wood JL (2007), Stewart GS (2003), Stewart GS (2003)	6
MDC1	8	CDC5L	2	affinity chromatography technology	Woods NT (2012)	1
FZR1	1	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhou Y (2003), Kramer ER (1998), Farhana L (2002), Cen B (2010), Sorensen CS (2001), Binne UK (2007), Wang X (2008), Tran K (2008), Wang LY (2012), Wang LY (2012), Ban KH (2007), Lv XB (2010), Huang KT (2012), Song MS (2011), Fukushima H (2013), Lau AW (2013), Cotto-Rios XM (2011), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Choi BH (2014), Jeganathan KB (2006), Fang G (1998), Sedgwick GG (2012), Kelly A (2014), Listovsky T (2013), Pavlides SC (2016), Huttlin EL (2017)	28
BUB1B	0	ANAPC10	0	affinity chromatography technology	Boekhout M (2015)	1
SMAD2	5	ANAPC10	0	affinity chromatography technology, pull down	Nourry C (2004), Nourry C (2004)	2
ANAPC15	0	ANAPC2	0	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
UBE2S	2	FZR1	1	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, pull down, affinity chromatography technology, pull down, pull down	Williamson A (2009), Williamson A (2009), Williamson A (2009), Williamson A (2009), Williamson A (2009), Wang W (2013), Brown NG (2014), Kelly A (2014)	8
CDC5L	2	HSP90AA1	7	affinity chromatography technology	Lleres D (2010)	1
RNF34	1	CDC20	1	affinity chromatography technology	Puliyappadamba VT (2011)	1
CDC5L	2	SMARCAD1	1	affinity chromatography technology	Lleres D (2010)	1
TTLL1	4	CDC16	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDC26	0	MAD2L1	0	biochemical	Masuda K (2015)	1
ANAPC11	0	PTTG1	0	enzymatic study, enzymatic study, enzymatic study	Gmachl M (2000), Tang Z (2001), Vodermaier HC (2003)	3
ANAPC4	0	FZR1	1	biochemical, biochemical, unspecified method, biochemical, affinity chromatography technology, affinity chromatography technology	Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Chang L (2015), Boekhout M (2015), Huttlin EL (2017)	6
LATS2	1	CDC26	0	affinity chromatography technology	Zhu C (2018)	1
FBXO5	2	ANAPC2	0	pull down	Miller JJ (2006)	1
FZR1	1	ANAPC11	0	affinity chromatography technology, pull down, unspecified method	Bassermann F (2008), Vodermaier HC (2003), Vodermaier HC (2003)	3
ANAPC2	0	CDC16	2	biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Gmachl M (2000), Vodermaier HC (2003), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
MDM2	2	LATS2	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Aylon Y (2006), Aylon Y (2006), Aylon Y (2006)	3
LATS2	1	ANAPC5	2	affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Couzens AL (2013), Couzens AL (2013), Zhu C (2018), Zhu C (2018)	4
MAGIX	0	ANAPC1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PRKDC	12	FZR1	1	affinity chromatography technology, affinity chromatography technology	Shang ZF (2015), Shang ZF (2015)	2
SOX2	4	ANAPC2	0	affinity chromatography technology	Cox JL (2013)	1
FZR1	1	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Stewart S (2005), Stewart S (2005), Wang Y (2007), Wang Y (2007), Tian W (2012), Hyun SY (2013), Hyun SY (2013)	7
CDC20	1	CDC26	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Masuda K (2015), Kelly A (2014), Craney A (2016)	4
RB1	2	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study	Iyer NG (2007), Iyer NG (2007), Chan HM (2001)	3
ANAPC11	0	CDC16	2	biochemical	Lu L (2013)	1
IST1	0	FZR1	1	affinity chromatography technology	Zhang X (2011)	1
CDC5L	2	ANAPC1	1	affinity chromatography technology	Lleres D (2010)	1
FZR1	1	ANAPC2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology	Stewart S (2005), Wen H (2010), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Huttlin EL (2017)	6
MAD2L1	0	CDC16	2	affinity chromatography technology	Li Y (1997)	1
SOX2	4	CDC26	0	affinity chromatography technology	Cox JL (2013)	1
UBE2S	2	CDC23	3	affinity chromatography technology, pull down, pull down	Wang W (2013), Brown NG (2014), Kelly A (2014)	3
CDC27	2	CDC16	2	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Ollendorff V (1997), Kallio M (1998), Gmachl M (2000), Kraft C (2003), Li Y (1997), Lara-Gonzalez P (2011), Binne UK (2007), van Zon W (2010), Dube P (2005), Holzmann J (2011), Hayes MJ (2006), Tugendreich S (1995), Havugimana PC (2012), Vodermaier HC (2003), Wan C (2015), Hein MY (2015), Kelly A (2014), Listovsky T (2013), Qiao R (2016), Huttlin EL (2017), Boldt K (2016)	22
TP53BP1	3	ANAPC10	0	affinity chromatography technology	Woods NT (2012)	1
TP53BP1	3	ANAPC7	2	affinity chromatography technology	Woods NT (2012)	1
PHF8	6	FZR1	1	affinity chromatography technology	Lim HJ (2013)	1
ANAPC15	0	ANAPC7	2	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
ANAPC4	0	CDC23	3	biochemical, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Hein MY (2015)	8
ANAPC13	0	COPS5	0	genetic interference	Horlbeck MA (2018)	1
RB1	2	ANAPC2	0	affinity chromatography technology, biochemical	Binne UK (2007), Binne UK (2007)	2
CDC27	2	ANAPC4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Mansfeld J (2011), Lara-Gonzalez P (2011), Mansfeld J (2011), Izawa D (2011), Ma HT (2011), Ma HT (2011), Ma HT (2011), Dube P (2005), Holzmann J (2011), Wolthuis R (2008), Havugimana PC (2012), Uzunova K (2012), Song MS (2011), Zhang Z (2012), Chang L (2014), Hein JB (2014), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Tran K (2010), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Hein MY (2015), Voets E (2015), Masuda K (2015), Boekhout M (2015), Craney A (2016), Qiao R (2016), Izawa D (2012), Hein JB (2016)	34
COPS5	0	PRKDC	12	affinity chromatography technology	Bennett EJ (2010)	1
ANAPC13	0	CDC23	3	biochemical, two hybrid, affinity chromatography technology, affinity chromatography technology, genetic interference	Havugimana PC (2012), Rolland T (2014), Hein MY (2015), Huttlin EL (2017), Horlbeck MA (2018)	5
CDC27	2	ANAPC7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Lara-Gonzalez P (2011), Tran K (2008), Dube P (2005), Holzmann J (2011), Havugimana PC (2012), Sedgwick GG (2012), Song MS (2011), Vodermaier HC (2003), Tran K (2010), Yamaguchi M (2015), Yamaguchi M (2015), Wan C (2015), Kelly A (2014), Craney A (2016), Qiao R (2016), Boldt K (2016)	19
ANAPC10	0	CDC16	2	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Kurasawa Y (1999), Havugimana PC (2012), Wan C (2015), Hein MY (2015)	4
MDC1	8	ANAPC10	0	affinity chromatography technology	Woods NT (2012)	1
SMAD2	5	CDC27	2	affinity chromatography technology	Stroschein SL (2001)	1
SMAD2	5	CREBBP	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	Xi Q (2008), Chan EC (2010), He W (2006), Chen W (2007), Colland F (2004), Cui Q (2005)	6
FZR1	1	ANAPC5	2	unspecified method, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Sedgwick GG (2012), Huttlin EL (2017)	3
EP300	36	SMAD2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Wotton D (1999), Pessah M (2001), Furumatsu T (2005), Wang J (2011), Suganuma T (2002)	5
UFD1	1	ANAPC2	0	two hybrid	Vinayagam A (2011)	1
ANAPC1	1	ANAPC4	0	biochemical, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Sumara I (2000), Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Hein JB (2014), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015)	9
EP300	36	TP53BP1	3	affinity chromatography technology	Jung SY (2005)	1
CDC27	2	ANAPC11	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Dube P (2005), Lu L (2013), Gmachl M (2000), Vodermaier HC (2003), Craney A (2016)	8
TTLL1	4	CDC27	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MAD2L1	0	ANAPC7	2	affinity chromatography technology, affinity chromatography technology	Sedgwick GG (2016), Sedgwick GG (2016)	2
CDC16	2	CREBBP	29	affinity chromatography technology	Turnell AS (2005)	1
CDC20	1	PTTG1	0	enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Braunstein I (2007), Eytan E (2006), Pfleger CM (2001), Kim HS (2009), Kwan PS (2013), Tian W (2012), Van Voorhis VA (2014), Lara-Gonzalez P (2011), Wu T (2010), Izawa D (2014), Hellmuth S (2014), Wu T (2010), Shoji S (2014), Lara-Gonzalez P (2011), Di Fiore B (2015), Lee SB (2015), Qiao R (2016), Alfieri C (2016), Izawa D (2012), Jia L (2016)	20
BUB1B	0	ANAPC7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chan GK (1999), Hutchins JR (2010), Sedgwick GG (2012), Sedgwick GG (2016)	4
ANAPC5	2	ANAPC7	2	biochemical, affinity chromatography technology	Havugimana PC (2012), Sedgwick GG (2012)	2
RB1	2	MDM2	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Hsieh JK (1999), Nguyen DX (2004), Zheng Z (2012), Sdek P (2005), Delston RB (2011), Delston RB (2011), Sdek P (2004), Sdek P (2004), Xiao ZX (1995), Xiao ZX (1995), Xiao ZX (1995), Uchida C (2006), Markham D (2006), Chan HM (2001), Chan HM (2001), Zhang H (2015), Zhang H (2015), Jaenicke RU (1996)	18
UBE2C	1	BUB1B	0	biochemical	Reddy SK (2007)	1
CREBBP	29	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Crusselle-Davis VJ (2007), Dohda T (2004), Dohda T (2004)	3
MDC1	8	FZR1	1	affinity chromatography technology	Woods NT (2012)	1
C16orf87	0	CDC16	2	affinity chromatography technology	Huttlin EL (2017)	1
SMARCAD1	1	CDC16	2	affinity chromatography technology	Rowbotham SP (2011)	1
FZR1	1	ANAPC7	2	unspecified method, affinity chromatography technology	Vodermaier HC (2003), Sedgwick GG (2012)	2
MDM2	2	HSP90AA1	7	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, biochemical, unspecified method, affinity chromatography technology	Lu TL (2010), Burch L (2004), Burch L (2004), Burch L (2004), Burch L (2004), Burch LR (2004), Okoro DR (2013)	7
ANAPC4	0	ANAPC15	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Mansfeld J (2011), Uzunova K (2012), Sedgwick GG (2012), Zhang Z (2012), Chang L (2014), Chang L (2015), Yamaguchi M (2015), Hein MY (2015)	8
CDC20	1	MAD2L1	0	affinity chromatography technology, two hybrid, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, unspecified method, pull down, affinity chromatography technology	Zhang Y (2001), Sihn CR (2003), Luo X (2000), Sironi L (2001), DAngiolella V (2003), Kallio MJ (2002), Wassmann K (1998), Kallio M (1998), Fang G (1998), Fang G (1998), Skoufias DA (2001), Nilsson J (2008), Privette LM (2008), Stegmeier F (2007), Ho CY (2010), Ho CY (2010), Mansfeld J (2011), Gao YF (2011), Braunstein I (2007), Visconti R (2010), Ma HT (2011), Townsend K (2009), Lee YJ (2008), DAngiolella V (2003), Tang Z (2001), Tang Z (2001), Sironi L (2001), Sironi L (2001), Ge S (2009), Mapelli M (2007), Tipton AR (2011), Mondal G (2006), Mondal G (2006), Westhorpe FG (2011), De Antoni A (2005), De Antoni A (2005), Kwan PS (2013), Katayama H (2012), Fava LL (2011), Santaguida S (2011), Mapelli M (2006), Eytan E (2013), Eytan E (2013), Hyun SY (2013), Han JS (2013), Rodriguez-Bravo V (2014), Fogeron ML (2013), Wang K (2014), Eytan E (2014), Hein JB (2014), Yen AH (2010), Yen AH (2010), Di Fiore B (2015), Hein MY (2015), Voets E (2015), Lischetti T (2014), Tipton AR (2013), Boekhout M (2015), Kelly A (2014), Craney A (2016), Sedgwick GG (2016), Sedgwick GG (2016), Izawa D (2012), Izawa D (2012), Jia L (2016), Jia L (2016), Kaisari S (2017), Yang M (2008), Kim S (2010), Kim S (2010)	70
FBXO5	2	FZR1	1	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Hsu JY (2002), Hsu JY (2002), Reimann JD (2001), Miller JJ (2006), Huttlin EL (2017)	5
SOX2	4	ANAPC7	2	affinity chromatography technology	Cox JL (2013)	1
FBXO5	2	ANAPC1	1	affinity chromatography technology, pull down	Miller JJ (2006), Miller JJ (2006)	2
COPS5	0	HSP90AA1	7	affinity chromatography technology	Bennett EJ (2010)	1
MDC1	8	ANAPC4	0	affinity chromatography technology	Woods NT (2012)	1
FZR1	1	UBE2C	1	pull down, pull down, enzymatic study	Jin L (2008), Williamson A (2009), Williamson A (2011)	3
ANAPC11	0	UBE2C	1	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Wu T (2010), Ke PY (2007), Jia L (2011), Braunstein I (2007), van Zon W (2010), Eytan E (2006), Ping Z (2012), Townsend K (2009), Huang NJ (2012), Chow C (2011), Zhang Z (2012), Bassermann F (2008), Wang W (2013), Frye JJ (2013), Han JS (2013), Chang L (2014), Lara-Gonzalez P (2011), He J (2013), Lau AW (2013), Han JS (2014), Sedgwick GG (2013), von Klitzing C (2011), Tang Z (2001), Shoji S (2014), Fukushima H (2013), Yamaguchi M (2015), Sajman J (2015), Brown NG (2015), Brown NG (2014), Cao J (2015), Zhang S (2016), Williamson A (2011), Qiao R (2016), Alfieri C (2016), Brown NG (2016), Li Q (2016), Izawa D (2012)	37
CDC20	1	ANAPC11	0	affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study	Nilsson J (2008), Chen TC (2014), Lee SB (2015), Alfieri C (2016)	4
MAD2L1	0	ANAPC1	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Sedgwick GG (2016)	2
PHF8	6	ANAPC5	2	affinity chromatography technology	Lim HJ (2013)	1
CDC5L	2	CDC20	1	affinity chromatography technology	Lleres D (2010)	1
FBXO5	2	ANAPC7	2	affinity chromatography technology, pull down	Miller JJ (2006), Miller JJ (2006)	2
SMARCAD1	1	ANAPC7	2	affinity chromatography technology	Rowbotham SP (2011)	1
UBE2S	2	ANAPC2	0	affinity chromatography technology, pull down, pull down, pull down	Wang W (2013), Brown NG (2014), Brown NG (2014), Kelly A (2014)	4
RNF34	1	FZR1	1	affinity chromatography technology, affinity chromatography technology	Puliyappadamba VT (2011), Puliyappadamba VT (2011)	2
PHF8	6	CDC27	2	affinity chromatography technology	Lim HJ (2013)	1
CDC5L	2	CDC23	3	affinity chromatography technology	Lleres D (2010)	1
ANAPC10	0	CDC26	0	biochemical	Wan C (2015)	1
ANAPC4	0	ANAPC11	0	affinity chromatography technology, biochemical, biochemical, pull down, biochemical, affinity chromatography technology	Mansfeld J (2011), Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015)	6
RNF34	1	UBE2D2	0	pull down	McDonald ER (2004)	1
CDC20	1	ANAPC7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nilsson J (2008), Townsend K (2009), Townsend K (2009), Townsend K (2009), Sedgwick GG (2012), Fogeron ML (2013), Hein JB (2014), Vodermaier HC (2003), Kelly A (2014), Craney A (2016), Craney A (2016), Qiao R (2016), Hein JB (2016)	13
ANAPC13	0	ANAPC7	2	biochemical, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2017)	2
GRAP2	0	CDC23	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ANAPC2	0	UBE2C	1	pull down, biochemical, pull down, x-ray crystallography, pull down	Tang Z (2001), Reddy SK (2007), Tang Z (2001), Brown NG (2015), Brown NG (2015)	5
SMARCAD1	1	ANAPC5	2	affinity chromatography technology	Rowbotham SP (2011)	1
ANAPC4	0	ANAPC7	2	affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Mansfeld J (2011), Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Sedgwick GG (2013), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Sedgwick GG (2016)	10
CDC5L	2	CDC27	2	affinity chromatography technology	Lleres D (2010)	1
BUB1B	0	ANAPC4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hutchins JR (2010), Mansfeld J (2011), Izawa D (2011), Sedgwick GG (2012), Hein JB (2014), Di Fiore B (2015), Voets E (2015), Tipton AR (2013), Boekhout M (2015), Boekhout M (2015), Sedgwick GG (2016), Izawa D (2012), Salsi V (2016)	13
GRAP2	0	ANAPC2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
C16orf87	0	CDC27	2	affinity chromatography technology	Huttlin EL (2017)	1
PHF8	6	ANAPC2	0	affinity chromatography technology	Lim HJ (2013)	1
UBE2S	2	FBXO5	2	affinity chromatography technology	Wang W (2013)	1
ANAPC10	0	CDC23	3	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Hein MY (2015)	3
NINL	1	ANAPC2	0	affinity chromatography technology	Wang Y (2007)	1
FZR1	1	CDC23	3	unspecified method, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Hein MY (2015), Huttlin EL (2017)	3
CDC26	0	ANAPC7	2	biochemical	Wan C (2015)	1
TP53BP1	3	ANAPC2	0	affinity chromatography technology	Woods NT (2012)	1
FZR1	1	CDC16	2	unspecified method, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Hein MY (2015), Huttlin EL (2017)	3
ANAPC11	0	CDC23	3	biochemical	Lu L (2013)	1
ANAPC1	1	CDC16	2	biochemical, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Sumara I (2000), Hutchins JR (2010), Havugimana PC (2012), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
EPHA4	3	FZR1	1	affinity chromatography technology	Fu AK (2011)	1
CDC27	2	ANAPC13	0	biochemical, biochemical, affinity chromatography technology, genetic interference	Holzmann J (2011), Havugimana PC (2012), Huttlin EL (2017), Horlbeck MA (2018)	4
SOX2	4	FZR1	1	affinity chromatography technology, enzymatic study	Fukushima H (2013), Fukushima H (2013)	2
SMARCAD1	1	CDC23	3	affinity chromatography technology	Rowbotham SP (2011)	1
ANAPC15	0	ANAPC1	1	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
GRAP2	0	ANAPC5	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDC5L	2	ANAPC2	0	affinity chromatography technology	Lleres D (2010)	1
HSP90AA1	7	RB1	2	genetic interference	Srivas R (2016)	1
RB1	2	CDC16	2	affinity chromatography technology, biochemical	Binne UK (2007), Binne UK (2007)	2
ZNF408	0	ANAPC2	0	affinity chromatography technology	Huttlin EL (2017)	1
COPS5	0	ANAPC2	0	affinity chromatography technology	Bennett EJ (2010)	1
UBE2S	2	UBE2C	1	affinity chromatography technology, affinity chromatography technology	Kuang P (2016), Kuang P (2016)	2
PRKDC	12	ANAPC2	0	affinity chromatography technology, affinity chromatography technology	Shang ZF (2015), Shang ZF (2015)	2
SMARCAD1	1	PRKDC	12	affinity chromatography technology	Rowbotham SP (2011)	1
MAGIX	0	CDC26	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ANAPC13	0	ANAPC10	0	affinity chromatography technology	Huttlin EL (2017)	1
ANAPC2	0	ANAPC5	2	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Gmachl M (2000), Vodermaier HC (2003), Vodermaier HC (2003)	4
FBXO5	2	ANAPC5	2	affinity chromatography technology, pull down	Miller JJ (2006), Miller JJ (2006)	2
PHF8	6	CDC20	1	affinity chromatography technology, affinity chromatography technology	Lim HJ (2013), Lim HJ (2013)	2
ANAPC5	2	CDC23	3	biochemical, affinity chromatography technology	Havugimana PC (2012), Hein MY (2015)	2
PTTG1	0	CREBBP	29	genetic interference	Vizeacoumar FJ (2013)	1
UBE2S	2	ANAPC1	1	pull down	Brown NG (2014)	1
CDC23	3	ANAPC7	2	biochemical, affinity chromatography technology, affinity chromatography technology	Wan C (2015), Hein MY (2015), Boldt K (2016)	3
FBXO2	0	UBE2D2	0	pull down, pull down	Yoshida Y (2002), Nelson RF (2006)	2
TP53BP1	3	CDC16	2	affinity chromatography technology	Woods NT (2012)	1
MDC1	8	ANAPC5	2	affinity chromatography technology, affinity chromatography technology	Coster G (2007), Woods NT (2012)	2
TTLL1	4	ANAPC4	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ANAPC15	0	ANAPC10	0	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
ANAPC7	2	CREBBP	29	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Turnell AS (2005), Turnell AS (2005), Turnell AS (2005), Townsend K (2009)	4
ZNF408	0	NINL	1	affinity chromatography technology	Huttlin EL (2017)	1
MDM2	2	UBE2D2	0	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Iyappan S (2010), Dou H (2012), Brenkman AB (2008), Fang S (2000), Szypowska AA (2011), Okamoto K (2009), Busso CS (2009), Maguire M (2008), Sehat B (2008), Uldrijan S (2007), Yang Y (2005), Jin Y (2004), Roxburgh P (2012), Shloush J (2011), Rinaldo C (2007), Cheng Q (2009), Amson R (2011), Li X (2009), David Y (2011), Sosin AM (2012), Schumacher FR (2013), Bista M (2013), Mikawa T (2014), Lohrum MA (2001), Fang S (2001), Saville MK (2004), Rodriguez MS (1999), Auger KR (2005), Wu PY (2003), Wu H (2015), Yamauchi T (2014), Nomura K (2017), Kurokawa M (2013)	33
ANAPC2	0	PTTG1	0	enzymatic study, pull down	Vodermaier HC (2003), Qiao R (2016)	2
COPS5	0	ANAPC7	2	affinity chromatography technology	Bennett EJ (2010)	1
UBE2C	1	CDC20	1	biochemical, pull down	Reddy SK (2007), Garnett MJ (2009)	2
FZR1	1	BUB1B	0	enzymatic study, pull down	Tian W (2012), Diaz-Martinez LA (2015)	2
C16orf87	0	ANAPC4	0	affinity chromatography technology	Huttlin EL (2017)	1
FBXO5	2	CDC20	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hsu JY (2002), Hsu JY (2002), Reimann JD (2001), Reimann JD (2001), Voets E (2015)	5
CDC27	2	MAD2L1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wassmann K (1998), Kallio M (1998), Li Y (1997), Li Y (1997), Lara-Gonzalez P (2011), Mansfeld J (2011), Visconti R (2010), Ma HT (2011), Sironi L (2001), Tipton AR (2011), Tipton AR (2011), Westhorpe FG (2011), Eytan E (2013), Lara-Gonzalez P (2011), Yen AH (2010), Hein MY (2015), Craney A (2016), Sedgwick GG (2016)	18
UBE2S	2	CDC27	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Williamson A (2009), Brown NG (2014), Kelly A (2014), Craney A (2016)	4
EP300	36	MDM2	2	pull down, affinity chromatography technology, biochemical, pull down, pull down, enzymatic study, affinity chromatography technology, biochemical, enzymatic study	Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Matt T (2004), Wang X (2004), Gillotin S (2010), Kobet E (2000), Nihira NT (2017)	9
UBE2S	2	ANAPC4	0	pull down, pull down	Brown NG (2014), Brown NG (2014)	2
ANAPC2	0	EP300	36	affinity chromatography technology	Turnell AS (2005)	1
IST1	0	CDC20	1	affinity chromatography technology	Zhang X (2011)	1
MAGIX	0	CDC16	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PHF8	6	ANAPC4	0	affinity chromatography technology	Lim HJ (2013)	1
ANAPC11	0	ANAPC10	0	pull down	Tang Z (2001)	1
LATS2	1	ANAPC7	2	affinity chromatography technology	Zhu C (2018)	1
TP53BP1	3	CDC27	2	affinity chromatography technology	Woods NT (2012)	1
BUB1B	0	ANAPC2	0	affinity chromatography technology	So J (2015)	1