PPI network (data source: BioGrid)

Symbol A GeneA coding DNM count Symbol B GeneB coding DNM count Interaction detection method Publication Evidence
MSH2 4 SUPT16H 4 biochemical Havugimana PC (2012) 1
RPA3 2 RPA2 0 biochemical, x-ray crystallography, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology Bochkareva E (1998), Bochkareva E (2002), Havugimana PC (2012), Du Y (2009), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017) 7
RPA2 0 PARP2 0 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
XPA 1 RPA1 0 two hybrid, pull down, affinity chromatography technology Li L (1995), Li L (1995), Lange SS (2009) 3
RPA1 0 RPA2 0 affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Shao RG (1999), Bochkareva E (2002), Gong Z (2011), Havugimana PC (2012), Kristensen AR (2012), Ghospurkar PL (2014), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Elia AE (2015), Elia AE (2015), Huttlin EL (2017), Feeney L (2017) 13
RPA4 0 RPA1 0 two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology Keshav KF (1995), Keshav KF (1995), Ghospurkar PL (2014), Huttlin EL (2015), Huttlin EL (2017) 5
XPA 1 RPA4 0 two hybrid, pull down Li L (1995), Li L (1995) 2
MSH2 4 RPA4 0 pull down Zhao J (2009) 1
XPC 1 XPA 1 affinity chromatography technology Bunick CG (2006) 1
RPA4 0 XPC 1 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
RPA1 0 MSH2 4 affinity chromatography technology, biochemical Marechal A (2014), Wan C (2015) 2
MSH2 4 MSH3 4 affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, biochemical, pull down Wang Y (2003), Guerrette S (1998), Bocker T (1999), Bocker T (1999), Acharya S (1996), Palombo F (1996), Havugimana PC (2012), Owen BA (2009) 8
PARP1 3 SUPT16H 4 enzymatic study Huang JY (2006) 1
RPA2 0 SSRP1 1 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
RPA4 0 RPA2 0 two hybrid, affinity chromatography technology Keshav KF (1995), Keshav KF (1995) 2
RPA3 2 MSH3 4 affinity chromatography technology Marechal A (2014) 1
RPA4 0 RPA3 2 two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Keshav KF (1995), Keshav KF (1995), Huttlin EL (2015), Huttlin EL (2017) 4
XPC 1 PARP1 3 affinity chromatography technology Huttlin EL (2017) 1
MSH3 4 XPA 1 pull down Zhao J (2009) 1
SSRP1 1 SUPT16H 4 affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology Birch JL (2009), Tan BC (2006), Tan BC (2006), Pavri R (2006), Huang JY (2006), Huang JY (2006), OConnell BC (2010), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017), Boldt K (2016) 12
RPA2 0 SUPT16H 4 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
RPA3 2 PARP1 3 affinity chromatography technology Marechal A (2014) 1
MSH3 4 RPA1 0 biochemical, affinity chromatography technology Havugimana PC (2012), Marechal A (2014) 2
RPA4 0 HMCES 1 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
RPA2 0 MSH3 4 affinity chromatography technology Marechal A (2014) 1
RPA4 0 SSRP1 1 affinity chromatography technology Huttlin EL (2015) 1
RPA1 0 PARP1 3 affinity chromatography technology Marechal A (2014) 1
RPA2 0 PARP1 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Marechal A (2014), Huttlin EL (2015), Huttlin EL (2017) 3
RPA2 0 MSH2 4 affinity chromatography technology Marechal A (2014) 1
XPA 1 RPA2 0 pull down, affinity chromatography technology Mer G (2000), Fan W (2010) 2
XPC 1 PARP2 0 affinity chromatography technology Huttlin EL (2017) 1
XPC 1 SUPT16H 4 affinity chromatography technology Huttlin EL (2017) 1
SSRP1 1 PARP1 3 affinity chromatography technology Huttlin EL (2017) 1
RPA3 2 RPA1 0 biochemical, x-ray crystallography, affinity chromatography technology, biochemical, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology Bochkareva E (1998), Bochkareva E (2002), Gong Z (2011), Havugimana PC (2012), Du Y (2009), Wan C (2015), Hein MY (2015), Elia AE (2015) 8
RPA2 0 XPC 1 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
SSRP1 1 XPC 1 affinity chromatography technology Huttlin EL (2017) 1
HMCES 1 APP 1 pull down, pull down Olah J (2011), Virok DP (2011) 2
PARP1 3 PARP2 0 affinity chromatography technology Schreiber V (2002) 1
RPA3 2 MSH2 4 affinity chromatography technology Marechal A (2014) 1
RPA4 0 PARP2 0 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
MSH3 4 RPA4 0 pull down Zhao J (2009) 1
RPA4 0 APP 1 pull down Olah J (2011) 1
RPA4 0 PARP1 3 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
RPA4 0 SUPT16H 4 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
RPA2 0 APP 1 pull down Olah J (2011) 1
RPA1 0 XPC 1 pull down Thoma BS (2005) 1
RPA2 0 HMCES 1 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
MSH2 4 XPA 1 pull down Zhao J (2009) 1
SUPT16H 4 RPA3 2 affinity chromatography technology Boldt K (2016) 1