PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
CD2AP	0	INPP5D	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bao M (2012), Bao M (2012), Bao M (2012)	3
GRB2	2	ARAP1	7	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Huttlin EL (2017)	2
CAPZA2	1	DAB2	1	affinity chromatography technology	Hein MY (2015)	1
SRC	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Burnham MR (1999), Song JJ (2010), Liu W (2010), Chen TC (2014)	4
SH3BP2	4	CBL	7	pull down, affinity chromatography technology	Deckert M (1998), GuezGuez A (2010)	2
GRB2	2	KHDRBS1	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, unspecified method, affinity chromatography technology, two hybrid	Liu SK (1998), Oneyama C (2002), Shen Z (1999), Shen Z (1999), Bandyopadhyay S (2010), Asbach B (2012), Bisson N (2011), Wang J (2011)	8
TGFBR1	2	PIK3R1	6	affinity chromatography technology	Krymskaya VP (1997)	1
CD2AP	0	CBLB	3	x-ray crystallography, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down	Moncalian G (2006), Moncalian G (2006), Moncalian G (2006), Ceregido MA (2013), Ceregido MA (2013)	5
SRC	2	BCAR1	6	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Burnham MR (1999), Burnham MR (1999), Wei L (2002), Hsia DA (2003), Kovacic-Milivojevic B (2001), Donaldson JC (2000), Angers-Loustau A (1999), Cabodi S (2004), Modzelewska K (2006), Sawada Y (2006), Riggins RB (2006), Riggins RB (2006)	12
CAPZA2	1	ARAP1	7	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SEPT2	4	SEPT6	0	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Rual JF (2005), Surka MC (2002), Kremer BE (2007), Rolland T (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	7
MVB12A	0	CD2AP	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsunematsu T (2010), Konishi H (2006), Konishi H (2006), Konishi H (2006), Morita E (2007)	5
CD2AP	0	SH3GL2	1	affinity chromatography technology, far western blotting	Lynch DK (2003), Lynch DK (2003)	2
ASAP1	1	CBLB	3	affinity chromatography technology	Nam JM (2007)	1
GRB2	2	SYNJ1	3	affinity chromatography technology, affinity chromatography technology	Bisson N (2011), Huttlin EL (2017)	2
SH3KBP1	1	MICALL1	1	affinity chromatography technology, affinity chromatography technology	Havrylov S (2009), Huttlin EL (2017)	2
SH3KBP1	1	CRK	0	affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000)	2
SH3KBP1	1	ARHGAP17	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havrylov S (2009), Wells CD (2006), Huttlin EL (2017)	3
SRC	2	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Olayioye MA (1999), Keely SJ (2000), Sato K (2000), Lee CW (2007), Jaganathan S (2011), Jaganathan S (2011), Lee IT (2010), Hitosugi T (2007), Chang CC (2012), Chang CC (2012), Tung WH (2011), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Yao Z (2017)	15
CAPZA2	1	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
SH3KBP1	1	INPP5D	2	affinity chromatography technology, two hybrid	Kowanetz K (2004), Conde C (2012)	2
STAP1	0	CAPZA2	1	affinity chromatography technology	Huttlin EL (2015)	1
STAP1	0	SH3KBP1	1	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Rolland T (2014), Huttlin EL (2015), Yu H (2011), Huttlin EL (2017)	4
RPGRIP1L	2	CAPZA2	1	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
SH3KBP1	1	GAS2L1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havrylov S (2009), Huttlin EL (2015), Huttlin EL (2017)	3
SPRY2	4	CBL	7	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wong ES (2001), Wong ES (2001), Wong ES (2001), Wong ES (2002), Wong ES (2002), Ng C (2008), Ng C (2008), Chandramouli S (2008), Visser GD (2005), Hall AB (2003), Hall AB (2003), Rubin C (2003), Rubin C (2003), Rubin C (2003), Egan JE (2002), Miraoui H (2010), Mayer CE (2010), Sun Q (2010), Severe N (2011), Haglund K (2005), Lao DH (2007), Lao DH (2007), Fong CW (2003), Fong CW (2003), Mason JM (2004), DaSilva J (2006), Lao DH (2006)	27
GRB2	2	PIK3R1	6	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Saleem A (1995), Saleem A (1995), Wang J (1995), Wang J (1995), Wang J (1995), Bandyopadhyay S (2010), Takahashi Y (1999), Gelkop S (2001), Jain SK (1997), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Cerboni C (1998), Bisson N (2011), Bisson N (2011), Weinger JG (2008), Weinger JG (2008), Weinger JG (2008)	18
CRK	0	ASAP1	1	pull down, affinity chromatography technology	Brown MT (1998), Brehme M (2009)	2
SH3KBP1	1	BCAR1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000), Tibaldi EV (2003)	3
CRK	0	SOS1	5	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Okada S (1996), Okada S (1996), Okada S (1996), Ingham RJ (1996), Brehme M (2009), Chen TC (2014)	6
ARAP1	7	INPP5D	2	two hybrid	Yoon HY (2011)	1
SH3KBP1	1	CAPZB	2	affinity chromatography technology, affinity chromatography technology	Bior BK (2013), Huttlin EL (2017)	2
SH3KBP1	1	ASAP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havrylov S (2009), Nam JM (2007), Nam JM (2007), Huttlin EL (2017)	4
GRB2	2	DAB2	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Bandyopadhyay S (2010), Tseng CP (1999), Mulkearns EE (2012)	3
KHDRBS1	1	CRK	0	pull down	Koch CA (1992)	1
PIK3R1	6	INPP5D	2	affinity chromatography technology	Zhang S (1999)	1
SH3GL2	1	CBL	7	affinity chromatography technology	Soubeyran P (2002)	1
SPRY2	4	SH3KBP1	1	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid	Haglund K (2005), Haglund K (2005), Haglund K (2005), Rolland T (2014)	4
CBL	7	SH3GL3	1	affinity chromatography technology	Petrelli A (2002)	1
EGFR	5	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ettenberg SA (1999), Tvorogov D (2002), Pennock S (2008), Umebayashi K (2008), Ng C (2008), Ng C (2008), Povlsen GK (2008), Khan EM (2008), Su X (2007), Shtiegman K (2007), Han W (2006), Visser GD (2005), Tsacoumangos A (2005), Prasad NK (2005), Gur G (2004), Kowanetz K (2004), Feshchenko EA (2004), Wu WJ (2003), Schmidt MH (2003), Bao J (2003), Rubin C (2003), Waterman H (1999), Bonaccorsi L (2007), Dey N (2011), Miraoui H (2010), Guo HB (2009), Tong J (2009), Tong J (2009), Sun Q (2010), Sanada F (2009), Rafiq K (2011), Ravid T (2004), Ravid T (2004), Duan L (2011), Duan L (2011), Haglund K (2005), Oksvold MP (2003), Oksvold MP (2003), Gui A (2012), Yang S (2006), de Melker AA (2004), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Raguz J (2007), de Melker AA (2004), Thien CB (2001), Kassenbrock CK (2004), Tarcic G (2009), Schroeder B (2012), Adachi S (2009), Shen F (2007), Mitsushima M (2006), Choi JH (2003), Burke P (2001), Tanaka S (1995), Meisner H (1995), Meisner H (1995), Kumar EA (2012), Tong J (2008), Dou H (2012), Levkowitz G (1999), Levkowitz G (1999), Bode AM (2009), Thomas C (2012), Meijer IM (2013), Chang CC (2012), Chang CC (2012), Smith CJ (2013), Gan Y (2010), Scott RP (2005), Fukazawa T (1996), Fukazawa T (1996), Fukazawa T (1996), Wang L (2013), Hong SY (2013), Sigismund S (2013), Sigismund S (2013), Sigismund S (2013), Meisner H (1997), Odintsova E (2013), Kondratov KA (2010), He Z (2014), Tong J (2014), Balaji K (2012), Kiuchi T (2014), Zhang B (2005), Waterman H (1999), Ha Thi HT (2015), Yao S (2015), Kortuem F (2015), Igloi Z (2015), Song F (2016), Song F (2016), Lin TY (2017), Conte A (2017)	96
CBL	7	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jain SK (1997), Liu SK (1998), Ettenberg SA (1999), Wong A (2002), Wong A (2002), Robertson H (1997), Donovan JA (1994), Park RK (1999), Erdreich-Epstein A (1999), Gesbert F (1998), Gesbert F (1998), Gesbert F (1998), Husson H (1997), Saci A (2002), Odai H (1997), Ng C (2008), Khan EM (2008), Bandyopadhyay S (2010), Jiang X (2003), Waterman H (2002), Miraoui H (2010), Ravid T (2004), Ingham RJ (1996), Erdreich-Epstein A (1997), Rellahan BL (2003), Izadi KD (1998), Wang Y (1999), Chu J (1998), Bonita DP (1997), Boussiotis VA (1997), Meisner H (1995), Meisner H (1995), Barber DL (1997), Shishido T (2000), Bartkiewicz M (1999), Buday L (1996), Tarcic G (2009), Belleudi F (2007), Brizzi MF (1996), Brenner B (2001), Donovan JA (1996), Donovan JA (1996), Donovan JA (1996), Gaston I (2004), Gaston I (2004), Tsygankov AY (1996), Tsygankov AY (1996), Hunter S (1997), Jain SK (1997), Levkowitz G (1996), Liu YC (1997), Odai H (1995), Odai H (1995), Meisner H (1995), Huang JY (2000), Panchamoorthy G (1996), Panchamoorthy G (1996), Yokouchi M (1997), Oda A (1996), Fukazawa T (1995), Fukazawa T (1995), Selbach M (2006), Brehme M (2009), Brehme M (2009), Fukazawa T (1995), Cerboni C (1998), Cerboni C (1998), Fixman ED (1997), Anderson SM (1997), Houtman JC (2006), Brizzi MF (1996), Scott RP (2005), Scott RP (2005), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Umehara H (2002), Taipale M (2014), Taipale M (2014), Grossmann A (2015), Grossmann A (2015), Igloi Z (2015), Huttlin EL (2017)	83
CD2AP	0	EGFR	5	affinity chromatography technology	Lynch DK (2003)	1
SRC	2	PDCD6IP	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Schmidt MH (2005), Schmidt MH (2005), Zhou X (2010), Zhou X (2010)	4
EGFR	5	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, imaging technique	Tong J (2009), Wen G (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Chen TC (2014)	6
KHDRBS1	1	SH3KBP1	1	unspecified method, affinity chromatography technology	Asbach B (2012), Havrylov S (2009)	2
GRB2	2	BCAR1	6	affinity chromatography technology, pull down, affinity chromatography technology	Wang X (2000), Angers-Loustau A (1999), Ambrogio C (2005)	3
ZFP36	2	SH3KBP1	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Kedar VP (2010), Kedar VP (2010), Kedar VP (2010)	3
SRC	2	KHDRBS1	1	two hybrid, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, fluorescent resonance energy transfe, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study	Stelzl U (2005), Oneyama C (2002), Koch CA (1992), Shen Z (1999), Shen Z (1999), Finan PM (1996), Asbach B (2012), Asbach B (2012), Asbach B (2012), Kaabeche K (2004), Pincheira R (2008), Wong G (1992), Williger BT (1997), Wong BR (1999)	14
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
RPGRIP1L	2	CTSB	5	bioid	Gupta GD (2015)	1
DAB2	1	TGFBR1	2	affinity chromatography technology	Hocevar BA (2001)	1
BLNK	2	CAPZB	2	affinity chromatography technology	Oellerich T (2011)	1
KHDRBS1	1	CD2AP	0	unspecified method	Asbach B (2012)	1
ARHGAP17	1	CRK	0	pull down	Richnau N (2001)	1
SOS1	5	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000)	2
INPP5D	2	DAB1	1	two hybrid	Conde C (2012)	1
SEPT9	1	SEPT6	0	affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Surka MC (2002), Rolland T (2014), Huttlin EL (2015), Yu H (2011), Huttlin EL (2017)	5
GRB2	2	SH3KBP1	1	pull down, pull down	Gout I (2000), Borinstein SC (2000)	2
EGFR	5	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Soubeyran P (2002), Szymkiewicz I (2002), Schmidt MH (2004), Schmidt MH (2003), Ronning SB (2011), Ronning SB (2011), Yang S (2006), Schmidt MH (2003)	8
SPRY2	4	GRB2	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method	Glienke J (2000), Chandramouli S (2008), Lao DH (2007), Mason JM (2004), Lao DH (2006), Lao DH (2006)	6
BLNK	2	CD2AP	0	affinity chromatography technology, affinity chromatography technology	Oellerich T (2011), Oellerich T (2011)	2
SH3KBP1	1	VPS37B	2	affinity chromatography technology, biochemical	Havrylov S (2009), Wan C (2015)	2
NPHS2	1	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Tossidou I (2010), Tossidou I (2010)	2
SH3GLB2	1	SH3KBP1	1	pull down, two hybrid	Petrelli A (2002), Soubeyran P (2002)	2
SH3KBP1	1	SEPT9	1	affinity chromatography technology, pull down, x-ray crystallography	Havrylov S (2009), Diesenberg K (2015), Diesenberg K (2015)	3
SH3KBP1	1	CBLB	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, pull down	Szymkiewicz I (2002), Szymkiewicz I (2002), Szymkiewicz I (2002), Havrylov S (2009), Moncalian G (2006), Jozic D (2005), Jozic D (2005), Kowanetz K (2003), Ceregido MA (2013), Ceregido MA (2013), Ceregido MA (2013)	11
SH3KBP1	1	HIP1R	5	affinity chromatography technology, affinity chromatography technology	Kowanetz K (2004), Kowanetz K (2004)	2
CD2	2	CD2AP	0	pull down, x-ray crystallography, affinity chromatography technology, x-ray crystallography, pull down, pull down	Hutchings NJ (2003), Moncalian G (2006), Tibaldi EV (2003), Ceregido MA (2013), Ceregido MA (2013), Ceregido MA (2013)	6
SH3KBP1	1	MAP3K4	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Aissouni Y (2005), Aissouni Y (2005), Aissouni Y (2005), Kedar VP (2010), Kedar VP (2010), Kim J (2013)	6
GRB2	2	PDCD6IP	3	two hybrid, two hybrid	Bandyopadhyay S (2010), Wang J (2011)	2
NPHS1	2	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology, imaging technique	Tossidou I (2010), Tossidou I (2010), Tossidou I (2010)	3
ARAP1	7	SH3KBP1	1	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Yoon HY (2011), Yoon HY (2011), Yoon HY (2011), Yoon HY (2011), Havrylov S (2009), Huttlin EL (2017)	6
EGFR	5	DNM2	2	affinity chromatography technology	Tong J (2014)	1
RPGRIP1L	2	CAPZB	2	affinity chromatography technology	Gupta GD (2015)	1
SH3KBP1	1	BLNK	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000), Watanabe S (2000), Niiro H (2012), Niiro H (2012), Oellerich T (2011)	6
SRC	2	ASAP1	1	two hybrid, pull down, affinity chromatography technology	Brown MT (1998), Brown MT (1998), Brown MT (1998)	3
SH3GL3	1	SH3KBP1	1	two hybrid, pull down, affinity chromatography technology, two hybrid	Petrelli A (2002), Petrelli A (2002), Petrelli A (2002), Vinayagam A (2011)	4
BLNK	2	CAPZA2	1	affinity chromatography technology	Oellerich T (2011)	1
SH3KBP1	1	SEPT6	0	affinity chromatography technology, pull down	Havrylov S (2009), Diesenberg K (2015)	2
PAK2	0	SRC	2	pull down	Kaerkkaeinen S (2006)	1
SH3KBP1	1	SEPT2	4	affinity chromatography technology, pull down	Havrylov S (2009), Diesenberg K (2015)	2
DAB1	1	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato Y (2007), Sato Y (2007), Bior BK (2013)	3
SH3KBP1	1	SH3KBP1	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Watanabe S (2000), Soubeyran P (2002), Verdier F (2002), Borthwick EB (2004), Kowanetz K (2004), Rolland T (2014)	6
GRB2	2	UBC	7	two hybrid	Bandyopadhyay S (2010)	1
BLNK	2	CBL	7	affinity chromatography technology, far western blotting	Yasuda T (2000), Yasuda T (2000)	2
SH3BP2	4	SRC	2	affinity chromatography technology	GuezGuez A (2010)	1
SH3KBP1	1	DAB2	1	affinity chromatography technology, two hybrid, affinity chromatography technology	Havrylov S (2009), Kowanetz K (2003), Kowanetz K (2003)	3
SH3KBP1	1	CTSB	5	two hybrid, affinity chromatography technology, affinity chromatography technology	Liu JP (2006), Liu JP (2006), Liu JP (2006)	3
PIK3R1	6	SH3KBP1	1	pull down, affinity chromatography technology, affinity chromatography technology, two hybrid	Gout I (2000), Tossidou I (2010), Borthwick EB (2004), Borthwick EB (2004)	4
PDCD6IP	3	CD2AP	0	affinity chromatography technology, affinity chromatography technology	Usami Y (2007), Morita E (2007)	2
CBL	7	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kassenbrock CK (2002), Rafiq K (2011), Rellahan BL (2003), Vantler M (2006), Shishido T (2000), Shishido T (2000), Song JJ (2010), Sanjay A (2006), Sanjay A (2006), Tanaka S (1995), Tanaka S (1995), Tanaka S (1995), Szymkiewicz I (2004), Hashimoto S (2006)	14
MVB12A	0	VPS37B	2	affinity chromatography technology, biochemical	Wunderley L (2014), Wan C (2015)	2
DAB2	1	SRC	2	pull down, affinity chromatography technology	Zhou J (2003), Zhou J (2003)	2
SOS1	5	EGFR	5	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Qian X (2000), Qian X (1998), Buday L (1994), Tong J (2009), Kurada BR (2009), Tong J (2008), Foerster S (2013), Tong J (2014), Kapoor GS (2010)	9
TGFBR1	2	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Yakymovych I (2015), Yakymovych I (2015)	2
CRK	0	GRB2	2	pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Riordan SM (2000), Matsuda M (1996), Okada S (1996), Okada S (1996), Garcia-Guzman M (2000), Brehme M (2009)	6
STAP1	0	CAPZB	2	affinity chromatography technology	Huttlin EL (2015)	1
CBL	7	CBLB	3	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Rorsman C (2016)	2
BCAR1	6	CD2AP	0	pull down, affinity chromatography technology	Kirsch KH (1999), Tibaldi EV (2003)	2
NPHS2	1	NPHS1	2	affinity chromatography technology, pull down	Schwarz K (2001), Schwarz K (2001)	2
RPGRIP1L	2	SH3KBP1	1	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
ASAP2	5	SH3KBP1	1	two hybrid, affinity chromatography technology	Rolland T (2014), Huttlin EL (2017)	2
ARHGAP27	2	SH3KBP1	1	pull down, affinity chromatography technology, two hybrid	Sakakibara T (2004), Sakakibara T (2004), Sakakibara T (2004)	3
DNM2	2	SH3GL2	1	pull down	Solomaha E (2005)	1
CBLB	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Ettenberg SA (1999), Lavagna-Sevenier C (1998), Lavagna-Sevenier C (1998), Elly C (1999), Bandyopadhyay S (2010), Vinayagam A (2011), Bisson N (2011), Blagoev B (2003), Rolland T (2014), Huttlin EL (2017)	10
CBLB	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lavagna-Sevenier C (1998), Elly C (1999), Elly C (1999), Alcazar I (2009), Fang D (2001)	5
EGFR	5	SH3GL3	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
ARHGAP17	1	GRB2	2	pull down	Richnau N (2001)	1
SH3GL2	1	SH3GL3	1	two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vinayagam A (2011), Ralser M (2005), Ralser M (2005), Ralser M (2005), Huttlin EL (2015), Huttlin EL (2017)	6
CRK	0	UBC	7	affinity chromatography technology	Brehme M (2009)	1
EGFR	5	CRK	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Schulze WX (2006), Hashimoto Y (1998), Hashimoto Y (1998), Katayama H (1999), Ota S (1998), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	9
EGFR	5	SH3GL2	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schmidt MH (2004), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Liu W (2014), Liu W (2014)	6
ZFP36	2	MAP3K4	1	affinity chromatography technology	Kedar VP (2010)	1
DDN	0	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Kawata A (2006), Kawata A (2006)	2
CRK	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique	Gelkop S (2001), Gelkop S (2001), Garcia-Guzman M (2000), Brehme M (2009), Grossmann A (2015), Chen TC (2014)	6
GRB2	2	MVB12A	0	affinity chromatography technology	Huttlin EL (2017)	1
SH3KBP1	1	SH3GL2	1	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid	Soubeyran P (2002), Soubeyran P (2002), Soubeyran P (2002), Schmidt MH (2004), Schmidt MH (2004), Vinayagam A (2011)	6
UBC	7	SH3KBP1	1	pull down, x-ray crystallography, pull down, x-ray crystallography, pull down, x-ray crystallography	Bezsonova I (2008), Korzhnev DM (2009), Ortega Roldan JL (2013), Ortega Roldan JL (2013), Stamenova SD (2007), Bezsonova I (2008)	6
SH3KBP1	1	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000), Petrelli A (2002), Soubeyran P (2002), Soubeyran P (2002), Szymkiewicz I (2002), Borinstein SC (2000), Schmidt MH (2006), Schmidt MH (2004), Schmidt MH (2004), Verdier F (2002), Verdier F (2002), Feshchenko EA (2004), Chandra V (2010), Niiro H (2012), Feng L (2011), Havrylov S (2009), Zhang J (2009), Zhang J (2009), Ababou A (2009), Le Bras S (2007), Jozic D (2005), Kowanetz K (2004), Kowanetz K (2003), Kowanetz K (2003), Tibaldi EV (2003), Tibaldi EV (2003), Take H (2000), Take H (2000), Schroeder B (2012), Schroeder B (2012), Peruzzi G (2007), Selbach M (2006), Sato S (2013), Taipale M (2014), Taipale M (2014), Diesenberg K (2015), Petrelli A (2002), Huttlin EL (2017)	39
SEPT9	1	SEPT2	4	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Surka MC (2002), Surka MC (2002), Wan C (2015), Huttlin EL (2017)	4
ARHGAP17	1	CD2AP	0	affinity chromatography technology	Wells CD (2006)	1
CBL	7	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Gesbert F (1998), Gesbert F (1998), Zhang S (1999), Dufour C (2008), Feshchenko EA (2004), Kassenbrock CK (2002), Fang D (2001), Valiya Veettil M (2011), Miao H (2002), Miao H (2002), Ueno H (1998), Gelkop S (2001), Wang Y (1999), Saci A (2000), Matsuo T (1996), Matsuo T (1996), Jackson JG (2000), Meisner H (1995), Saci A (1999), Saci A (1999), Beckwith M (1996), Beckwith M (1996), Song JJ (2010), Hartley D (1996), Finkelstein LD (2000), Ren SY (2005), Hunter S (1997), Hunter S (1997), Jain SK (1997), Jain SK (1997), Swaminathan G (2007), van Leeuwen JE (1999), Ren SY (2005), Ren SY (2005), Alcazar I (2009), Liu YC (1997), Matsuo T (1996), Matsuo T (1996), Lottin-Divoux S (2006), Kitanaka A (1996), Liu YC (1997), Grossmann AH (2004), Panchamoorthy G (1996), Panchamoorthy G (1996), Chernock RD (2001), Chernock RD (2001), Fukazawa T (1995), Fukazawa T (1995), Brehme M (2009), Hakak Y (2000), Hakak Y (2000), Fukazawa T (1995), Liu Y (1999), Cerboni C (1998), Cerboni C (1998), Momose H (2003), Fukazawa T (1996), Fukazawa T (1996), Bulut GB (2013), Bulut GB (2013), Grossmann A (2015)	61
SH3KBP1	1	SYNJ1	3	affinity chromatography technology, far western blotting, affinity chromatography technology	Kurakin AV (2003), Kurakin AV (2003), Havrylov S (2009)	3
GRB2	2	ASAP2	5	two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Huttlin EL (2017)	2
DAB2	1	INPP5D	2	pull down	Morris SM (2001)	1
SH3KBP1	1	SH3D19	3	affinity chromatography technology, affinity chromatography technology	Havrylov S (2009), Huttlin EL (2017)	2
SRC	2	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Narita T (2005), Schroeder B (2012)	2
GRB2	2	INPP5D	2	unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kavanaugh WM (1996), Kavanaugh WM (1996), de Castro RO (2012), Ho JM (2002)	4
CAPZA2	1	HIP1R	5	affinity chromatography technology	Hein MY (2015)	1
LOX	0	CBL	7	affinity chromatography technology	Sato S (2013)	1
GRB2	2	CD2AP	0	affinity chromatography technology, affinity chromatography technology, two hybrid	Brehme M (2009), Bisson N (2011), Wang J (2011)	3
CBL	7	SOS1	5	affinity chromatography technology	Wang Y (1999)	1
PDCD6IP	3	SH3GL2	1	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Schmidt MH (2004), Schmidt MH (2004), Ichioka F (2007), Ichioka F (2007)	4
ARAP3	2	ASAP1	1	affinity chromatography technology	Kowanetz K (2004)	1
UBC	7	KHDRBS1	1	pull down	Zhang X (2017)	1
STAP1	0	CD2AP	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PIK3R1	6	SOS1	5	imaging technique	Chen TC (2014)	1
CD2AP	0	CAPZA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Titz B (2010), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	4
SRC	2	GRB2	2	affinity chromatography technology, affinity chromatography technology	Wan KF (2003), Saci A (2002)	2
BCAR1	6	CRK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology	Zhou B (2004), Di Stefano P (2004), Hsia DA (2003), Hsia DA (2003), Gu J (2001), Garton AJ (1999), Angers-Loustau A (1999), Qiu W (1998), Blaukat A (1999), Wang JF (2000), Holcomb M (2006), Wu Y (2005), Cho SY (2000), Modzelewska K (2006), Modzelewska K (2006), Brehme M (2009), Cho SY (2002), Cho SY (2002), Mielenz D (2001), Peterson ME (2008), Liu BA (2012), Larsson H (1999)	22
SPRY2	4	DNM2	2	two hybrid	Vinayagam A (2011)	1
DNM2	2	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Schroeder B (2010), Schroeder B (2010), Havrylov S (2009), Wan C (2015)	4
PIK3R1	6	KHDRBS1	1	affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Sanchez-Margalet V (2001), Shen Z (1999), Shen Z (1999), Asbach B (2012), Asbach B (2012), Asbach B (2012), Sung CK (1994), Sung CK (1994)	8
MVB12A	0	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsunematsu T (2010), Havrylov S (2009), Konishi H (2006), Konishi H (2006)	4
SH3KBP1	1	CD2AP	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tossidou I (2010), Gaidos G (2007), Huttlin EL (2017)	3
EGFR	5	CBLB	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Schulze WX (2006), Ettenberg SA (1999), Davies GC (2006), Davies GC (2006), Tong J (2009), Ettenberg SA (2001), Tong J (2008), Levkowitz G (1999), Tong J (2014)	9
GRB2	2	ASAP1	1	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Brehme M (2009), Bisson N (2011), Wang J (2011), Huttlin EL (2017)	5
GRB2	2	SYNJ2	2	two hybrid	Bandyopadhyay S (2010)	1
CBL	7	UBC	7	x-ray crystallography, pull down, affinity chromatography technology, pull down, enzymatic study, pull down, enzymatic study, x-ray crystallography, pull down, pull down, enzymatic study	Peschard P (2007), Peschard P (2007), Davies GC (2004), Davies GC (2004), Kassenbrock CK (2004), Zhou ZR (2008), Kim M (2004), Dou H (2013), Liu N (2015), Buetow L (2016), Kliza K (2017)	11
GRB2	2	SHKBP1	4	pull down	Borinstein SC (2000)	1
SH3KBP1	1	CDC27	2	affinity chromatography technology, affinity chromatography technology	Havrylov S (2009), Huttlin EL (2017)	2
SH3KBP1	1	ARAP3	2	affinity chromatography technology, affinity chromatography technology	Kowanetz K (2004), Kowanetz K (2004)	2
CRK	0	SEPT6	0	two hybrid	Grossmann A (2015)	1
DNM2	2	PIK3R1	6	affinity chromatography technology	Feng H (2012)	1
NPHS1	2	CD2AP	0	affinity chromatography technology	Tossidou I (2010)	1
EGFR	5	UBC	7	affinity chromatography technology, affinity chromatography technology	Tong J (2009), Bishop N (2002)	2
SPRY2	4	CTSB	5	two hybrid	Vinayagam A (2011)	1
ASAP2	5	SRC	2	affinity chromatography technology	Andreev J (1999)	1
NPHS2	1	CD2AP	0	affinity chromatography technology, pull down, affinity chromatography technology	Schwarz K (2001), Schwarz K (2001), Tossidou I (2010)	3
ASAP1	1	CBL	7	affinity chromatography technology	Nam JM (2007)	1
BCAR1	6	PIK3R1	6	affinity chromatography technology, pull down	Li E (2000), Li E (2000)	2
RPGRIP1L	2	CD2AP	0	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
SH3KBP1	1	PAK2	0	affinity chromatography technology, far western blotting	Kurakin AV (2003), Kurakin AV (2003)	2
INPP5D	2	CBL	7	affinity chromatography technology	Bao M (2012)	1
DNM2	2	SRC	2	pull down	Solomaha E (2005)	1
UBC	7	CD2AP	0	pull down, x-ray crystallography	Ortega Roldan JL (2013), Ortega Roldan JL (2013)	2
DNM2	2	GRB2	2	pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	Solomaha E (2005), Brehme M (2009), Bisson N (2011), Elhamdani A (2006), Wang J (2011), Huttlin EL (2017)	6
GRB2	2	SH3D19	3	two hybrid	Bandyopadhyay S (2010)	1
BCAR1	6	CBL	7	affinity chromatography technology	Sawasdikosol S (1996)	1
ARHGAP17	1	SRC	2	pull down	Richnau N (2001)	1
EGFR	5	PDCD6IP	3	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Schmidt MH (2004), Schmidt MH (2003), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
ARHGAP17	1	CAPZB	2	affinity chromatography technology	Wells CD (2006)	1
CRK	0	CBLB	3	affinity chromatography technology, two hybrid, two hybrid	Brehme M (2009), Grossmann A (2015), Grossmann A (2015)	3
UBC	7	CBLB	3	pull down, pull down, pull down, pull down, enzymatic study	De Schutter J (2009), Fenner BJ (2009), Zhou ZR (2008), Raasi S (2005), Kim M (2004)	5
CD2	2	SH3KBP1	1	pull down, two hybrid, affinity chromatography technology, x-ray crystallography, pull down, pull down	Hutchings NJ (2003), Tibaldi EV (2003), Tibaldi EV (2003), Ceregido MA (2013), Ceregido MA (2013), Ceregido MA (2013)	6
CD2AP	0	DNM2	2	affinity chromatography technology	Lynch DK (2003)	1
SH3KBP1	1	SH3BP2	4	affinity chromatography technology, two hybrid, affinity chromatography technology	Havrylov S (2009), Le Bras S (2007), Le Bras S (2007)	3
CAPZA2	1	GAS2L1	2	affinity chromatography technology	Hein MY (2015)	1
CRK	0	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, two hybrid	Gesbert F (1998), Husson H (1997), Ingham RJ (1996), Ingham RJ (1996), Delehanty LL (2003), Garcia-Guzman M (2000), Garcia-Guzman M (2000), Barber DL (1997), Buday L (1996), Sawasdikosol S (1996), Sawasdikosol S (1996), Thien CB (1997), van Leeuwen JE (1999), Ribon V (1996), Lottin-Divoux S (2006), Reedquist KA (1996), Brehme M (2009), Brehme M (2009), Ota S (1998), Peterson ME (2008), Liu BA (2012), Fukazawa T (1996), Umehara H (2002), Grossmann A (2015)	24
LOX	0	CD2AP	0	affinity chromatography technology, affinity chromatography technology	Sato S (2013), Sato S (2013)	2
GRB2	2	SOS1	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Liu SK (1998), Oneyama C (2002), Puil L (1994), Robinson A (1996), Li N (1993), Wong A (2002), Wong A (2002), Reif K (1994), DAngelo G (1999), Nel AE (1995), Pandey P (1995), Buday L (1994), Tong XK (2000), Park RK (1999), Okada S (1996), Okada S (1996), Okada S (1996), Germani A (1999), Park RK (1999), Chin H (1997), Saci A (2002), Sastry L (1997), Spivak-Kroizman T (1994), Ingham RJ (1996), Wang Y (1999), Chu J (1998), Brehme M (2009), Houtman JC (2006), Lao DH (2006), Bisson N (2011), Wang J (2011), Ng MY (2017), Huttlin EL (2017), Kapoor GS (2010), Saito T (2004), Klint P (1995)	37
UBC	7	CD2	2	pull down	Nathan JA (2013)	1
SH3KBP1	1	PDCD6IP	3	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down	Schmidt MH (2004), Rauch S (2011), Havrylov S (2009), Usami Y (2007), Ichioka F (2007), Ichioka F (2007), Schmidt MH (2005), Carlton JG (2008), Chen B (2000)	9
ZFP36	2	SPRY2	4	affinity chromatography technology	Kang JG (2011)	1
UBC	7	PDCD6IP	3	pull down	Zhang X (2017)	1
ARHGAP17	1	PIK3R1	6	pull down	Richnau N (2001)	1
CD2AP	0	CAPZB	2	affinity chromatography technology, affinity chromatography technology	Bao M (2012), Titz B (2010)	2
BLNK	2	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Fu C (1998), Engels N (2001), Fusaki N (2000), Wienands J (1998), Oellerich T (2011), Oellerich T (2011)	6
CAPZA2	1	CAPZB	2	biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	5
CRK	0	SRC	2	affinity chromatography technology, affinity chromatography technology	Hsia DA (2003), Garcia-Guzman M (2000)	2
SH3KBP1	1	SHKBP1	4	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Borinstein SC (2000), Feng L (2011), Feng L (2011), Havrylov S (2009)	4
SH3KBP1	1	SYNJ2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havrylov S (2009), Kowanetz K (2004), Kowanetz K (2004), Huttlin EL (2017)	4
SH3BP2	4	GRB2	2	pull down	Deckert M (1998)	1
CD2AP	0	CBL	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Haglund K (2004), Haglund K (2004), Kirsch KH (2001), Kirsch KH (2001), Cormont M (2003), Lynch DK (2003), Tibaldi EV (2003), Bao M (2012), Yao B (2007), Selbach M (2006), Taipale M (2014), Taipale M (2014), Igloi Z (2015)	13
SYNJ1	3	SH3GL2	1	pull down, pull down, affinity chromatography technology	Micheva KD (1997), Micheva KD (1997), Micheva KD (1997)	3
GRB2	2	VPS37B	2	affinity chromatography technology	Huttlin EL (2017)	1
LOX	0	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Sato S (2013), Sato S (2013)	2