PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
H2AFX	1	HIST2H2BE	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Du YC (2006), Du YC (2006), Lee HS (2010)	3
H2AFX	1	DHX9	3	affinity chromatography technology, pull down, affinity chromatography technology	Mischo HE (2005), Mischo HE (2005), Mischo HE (2005)	3
H2AFX	1	PPM1G	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Heo K (2008), Heo K (2008), Huttlin EL (2017)	3
DHX9	3	XRCC5	5	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Q (2005), Zhang S (2004), Zhang S (2004), Zhang S (2004), Sand-Dejmek J (2011)	5
TOPORS	6	H2AFX	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Seong KM (2012), Seong KM (2012), Seong KM (2012), Seong KM (2012)	4
H2AFX	1	HIST1H4A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Du YC (2006), Lee HS (2010), Yang X (2010)	3
PRKDC	12	ATM	9	unspecified method, affinity chromatography technology, affinity chromatography technology	Kim ST (1999), Suzuki K (1999), Suzuki K (1999)	3
TP53BP1	3	H2AFX	1	affinity chromatography technology, imaging technique, imaging technique, unspecified method, imaging technique, affinity chromatography technology, imaging technique, imaging technique	Sengupta S (2004), Sengupta S (2004), Fernandez-Capetillo O (2002), Ward IM (2003), Walters DK (2011), Stewart GS (2003), Fraser M (2011), Rassoolzadeh H (2015)	8
CSNK2A1	15	PRKDC	12	affinity chromatography technology, imaging technique, affinity chromatography technology	Olsen BB (2012), Olsen BB (2012), Olsen BB (2012)	3
WRAP53	1	RNF8	2	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Henriksson S (2014), Henriksson S (2014), Rassoolzadeh H (2015), Rassoolzadeh H (2015)	4
RNF2	1	CSNK2A1	15	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Cao Q (2014), Gao Z (2014), Hauri S (2016), Hauri S (2016)	5
PARP1	3	XRCC5	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Ju BG (2006), Galande S (1999), Galande S (1999), Galande S (1999), Idogawa M (2007), Li B (2004), Li B (2004), Yin H (2006), Yin H (2006), Sand-Dejmek J (2011), Wu T (2013)	11
SMARCA4	19	NPM1	0	affinity chromatography technology	Tando T (2010)	1
RNF2	1	XRCC5	5	affinity chromatography technology	Cao Q (2014)	1
HIST1H4A	0	PPM1G	1	biochemical	Kristensen AR (2012)	1
HIST1H4A	0	SUPT16H	4	affinity chromatography technology	Huttlin EL (2017)	1
RNF8	2	MDC1	8	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Huen MS (2007), Mailand N (2007), Mailand N (2007), Kolas NK (2007), Kolas NK (2007), Watanabe S (2013), Henriksson S (2014), Henriksson S (2014), Rassoolzadeh H (2015)	9
ATM	9	BRCA2	6	pull down	Wang X (2004)	1
NPM1	0	PARP1	3	affinity chromatography technology	Haindl M (2008)	1
NPM1	0	SUPT16H	4	affinity chromatography technology	Hein MY (2015)	1
ATM	9	MRE11	3	unspecified method, biochemical, affinity chromatography technology	Kim ST (1999), Wang Y (2000), Falck J (2005)	3
H2AFX	1	ILF2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang X (2010), Huttlin EL (2015), Huttlin EL (2017)	3
PRKDC	12	MRE11	3	unspecified method	Kim ST (1999)	1
BRCA1	7	H2AFX	1	pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, enzymatic study, affinity chromatography technology, imaging technique	Mallery DL (2002), Paull TT (2000), Ray A (2009), Tsai WB (2008), Mok MT (2010), Nelson AC (2010), Chen A (2002), Dutta D (2015), Dutta D (2015)	9
ILF2	3	XRCC5	5	affinity chromatography technology	Shi L (2007)	1
MDC1	8	PRKDC	12	pull down, affinity chromatography technology, imaging technique, affinity chromatography technology	Lou Z (2004), Lou Z (2004), Lou Z (2004), Lou Z (2004)	4
NPM1	0	PPM1G	1	affinity chromatography technology	Chen R (2013)	1
MRE11	3	XRCC6	3	two hybrid, pull down, affinity chromatography technology, biochemical	Goedecke W (1999), Goedecke W (1999), Goedecke W (1999), Wan C (2015)	4
TOPORS	6	PARP1	3	affinity chromatography technology	Pungaliya P (2007)	1
PRKDC	12	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, enzymatic study, affinity chromatography technology	Shao RG (1999), Drouet J (2005), Gottlieb TM (1993), Shamanna RA (2011), Shamanna RA (2011), Havugimana PC (2012), Sartorius CA (2000), Sartorius CA (2000), Hein MY (2015)	9
NPM1	0	HIST1H4A	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Swaminathan V (2005), Shuaib M (2010), Shuaib M (2010), Kleiner RE (2018)	4
PARP1	3	SUPT16H	4	enzymatic study	Huang JY (2006)	1
USP11	3	H2AFX	1	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Yu M (2016), Yu M (2016), Yu M (2016), Yu M (2016)	4
MDC1	8	NBN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, unspecified method, pull down, affinity chromatography technology, imaging technique	Xu X (2003), Goldberg M (2003), Goldberg M (2003), Lukas C (2004), Cha H (2010), Stewart GS (2003), Stewart GS (2003), Stewart GS (2003), Lou Z (2004), Hari FJ (2010), Lu CS (2012), Wu L (2008), Wu L (2008), Wu L (2008), Chapman JR (2008), Chapman JR (2008), Chapman JR (2008), Chapman JR (2008)	18
NPM1	0	BRCA1	7	affinity chromatography technology, affinity chromatography technology	Sato K (2004), Ertych N (2016)	2
DHX9	3	ILF2	3	biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012)	2
SMARCA4	19	HIST2H2BE	1	unspecified method	Shen W (2007)	1
MDC1	8	ATM	9	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique	Xu X (2003), Kolas NK (2007), Stewart GS (2003), Stewart GS (2003), Rassoolzadeh H (2015)	5
H2AFX	1	TRAF6	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Rezaeian AH (2017), Rezaeian AH (2017), Rezaeian AH (2017)	3
ILF2	3	XRCC6	3	affinity chromatography technology	Shi L (2007)	1
NBN	1	RNF8	2	affinity chromatography technology, enzymatic study, affinity chromatography technology	Lu CS (2012), Lu CS (2012), Monsalve DM (2016)	3
XRCC5	5	NBN	1	affinity chromatography technology	Falck J (2005)	1
MRE11	3	RNF8	2	affinity chromatography technology	Lu CS (2012)	1
PRKDC	12	ILF2	3	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ting NS (1998), Ting NS (1998), Shi L (2007), Karmakar S (2010)	4
H2AFX	1	CALR	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Du YC (2006), Du YC (2006), Yang X (2010), Yang X (2010)	4
SSRP1	1	SUPT16H	4	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Birch JL (2009), Tan BC (2006), Tan BC (2006), Pavri R (2006), Huang JY (2006), Huang JY (2006), OConnell BC (2010), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	12
H2AFX	1	NPM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Du YC (2006), Du YC (2006), Huttlin EL (2015), Huttlin EL (2017)	4
RNF2	1	DHX9	3	affinity chromatography technology	Cao Q (2014)	1
TP53BP1	3	BRCA1	7	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Matsuoka S (2007), Wang B (2002), Bohgaki T (2011), Ertych N (2016)	4
NPM1	0	HIST2H2BE	1	pull down, affinity chromatography technology	Swaminathan V (2005), Hein MY (2015)	2
SMARCA4	19	MDC1	8	biochemical	Wan C (2015)	1
PRKDC	12	BRCA1	7	unspecified method	Kim ST (1999)	1
BRCA1	7	MRE11	3	biochemical, pull down, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Paull TT (2001), Chiba N (2001), Chiba N (2001), Zhong Q (1999), Greenberg RA (2006), Zhao GY (2007), Hill SJ (2014), Suhasini AN (2013)	9
BMI1	0	RNF2	1	biochemical, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, biochemical, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Cao R (2005), Cao R (2005), Ben-Saadon R (2006), Li Z (2006), Maertens GN (2009), Wei J (2006), Gao Z (2012), Gao Z (2012), Gao Z (2012), Gao Z (2012), Pan MR (2011), Pan MR (2011), Voncken JW (2005), Woodsmith J (2012), Voncken JW (2003), Woodsmith J (2012), Li Z (2006), Li Z (2006), McGinty RK (2014), Cao Q (2014), Cao Q (2014), Hein MY (2015), Balasubramanian S (2015), Taherbhoy AM (2015), Taherbhoy AM (2015), Abdouh M (2016), Sanchez A (2016), Wheaton K (2017), Hauri S (2016), Hauri S (2016)	30
PARP1	3	BRCA2	6	genetic interference, genetic interference	Srivas R (2016), Ward TA (2017)	2
MDC1	8	XRCC5	5	pull down, affinity chromatography technology	Lou Z (2004), Lou Z (2004)	2
MDC1	8	H2AFX	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, unspecified method, imaging technique	Stewart GS (2003), Stewart GS (2003), Xu X (2003), Lukas C (2004), Strauss C (2011), Strauss C (2011), Stewart GS (2003), Stewart GS (2003), Stewart GS (2003), Pan MR (2011), Pei H (2011), Campbell SJ (2010), Rassoolzadeh H (2015)	13
H2AFX	1	SSRP1	1	affinity chromatography technology, pull down, affinity chromatography technology	Du YC (2006), Heo K (2008), Huttlin EL (2017)	3
SSRP1	1	HIST2H2BE	1	pull down	Winkler DD (2011)	1
CSNK2A1	15	SSRP1	1	biochemical, enzymatic study, affinity chromatography technology, biochemical, affinity chromatography technology	Havugimana PC (2012), Zhang M (2011), So J (2015), Wan C (2015), Huttlin EL (2017)	5
XRCC5	5	PRKDC	12	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, biochemical, affinity chromatography technology	Jin S (1997), Matheos D (2002), Gell D (1999), Drouet J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Olsen BB (2012), Olsen BB (2012), Sand-Dejmek J (2011), Sartorius CA (2000), Sartorius CA (2000), Drouet J (2006), Drouet J (2006), Sibanda BL (2010), Wan C (2015), Hein MY (2015)	17
RNF8	2	XRCC5	5	affinity chromatography technology	Feng L (2012)	1
BRCA1	7	ILF2	3	affinity chromatography technology	Ertych N (2016)	1
H2AFX	1	BMI1	0	imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ginjala V (2011), Pan MR (2011), Pan MR (2011), Pan MR (2011)	4
BMI1	0	PRKDC	12	affinity chromatography technology	Facchino S (2010)	1
BMI1	0	ILF2	3	affinity chromatography technology	Cao Q (2014)	1
XRCC6	3	SSRP1	1	affinity chromatography technology	Huttlin EL (2017)	1
CSNK2A1	15	BRCA1	7	pull down	OBrien KA (1999)	1
USP11	3	MRE11	3	affinity chromatography technology	Sowa ME (2009)	1
BMI1	0	USP11	3	affinity chromatography technology, affinity chromatography technology, pull down	Maertens GN (2010), Maertens GN (2010), Maertens GN (2010)	3
MDC1	8	TP53BP1	3	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, imaging technique, affinity chromatography technology	Eliezer Y (2009), Eliezer Y (2009), Eliezer Y (2009), Wood JL (2007), Stewart GS (2003), Stewart GS (2003)	6
TP53I3	1	H2AFX	1	imaging technique, affinity chromatography technology, affinity chromatography technology	Lee JH (2010), Lee JH (2010), Lee JH (2010)	3
XRCC5	5	XRCC6	3	two hybrid, biochemical, two hybrid, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, enzymatic study, x-ray crystallography, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology	Gell D (1999), Barlev NA (1998), Yang CR (1999), Singleton BK (1999), Song K (2000), Gell D (1999), Gell D (1999), Willis DM (2002), Willis DM (2002), Drouet J (2005), Drouet J (2005), Cohen HY (2004), Lan L (2010), Cooper MP (2000), Cooper MP (2000), Velma V (2010), Zheng Y (2011), Sucharov CC (2004), Sucharov CC (2004), Sibani S (2005), Sibani S (2005), Walker JR (2001), Nick McElhinny SA (2000), Nick McElhinny SA (2000), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Pucci S (2009), Trougakos IP (2009), Havugimana PC (2012), Sartorius CA (2000), Sartorius CA (2000), Rivera-Calzada A (2007), Kelavkar UP (2001), Kelavkar UP (2001), Kristensen AR (2012), Kim E (2008), Wan C (2015), Hein MY (2015), Hein MY (2015), Nolens G (2009), Nolens G (2009), Nolens G (2009), Nolens G (2009), Huttlin EL (2017), Fantini D (2017)	46
NBN	1	PRKDC	12	pull down, affinity chromatography technology	Falck J (2005), Falck J (2005)	2
ATM	9	BRCA1	7	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Gatei M (2000), Gatei M (2000), Kim ST (1999), Cortez D (1999), Cortez D (1999), Tibbetts RS (2000), Wang Y (2000), Mu JJ (2007), Tsai WB (2008), Gatei M (2000), Gatei M (2000), Gatei M (2000)	12
BMI1	0	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Facchino S (2010), Cao Q (2014)	2
XRCC6	3	SUPT16H	4	affinity chromatography technology	Huttlin EL (2017)	1
BMI1	0	PARP1	3	affinity chromatography technology	Facchino S (2010)	1
BRCA2	6	BRCA1	7	affinity chromatography technology, two hybrid, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sarkisian CJ (2001), Reuter TY (2003), Dong Y (2003), Chen J (1998), Chen J (1998), Villarroel MC (2011), Kumaraswamy E (2007), Sy SM (2009), Sy SM (2009), Sy SM (2009), Johnson N (2013), Hill SJ (2014), Loke J (2015)	13
RNF8	2	HIST2H2BE	1	enzymatic study	Mattiroli F (2012)	1
CSNK2A1	15	H2AFX	1	imaging technique, affinity chromatography technology, enzymatic study	Olsen BB (2012), Basnet H (2014), Basnet H (2014)	3
USP11	3	WRAP53	1	biochemical	Havugimana PC (2012)	1
H2AFX	1	RNF2	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Pan MR (2011), Pan MR (2011), Pan MR (2011), Pan MR (2011), Yang XX (2016)	5
BRCA1	7	SSRP1	1	genetic interference, imaging technique	Hill SJ (2014), Hill SJ (2014)	2
STK4	1	H2AFX	1	enzymatic study, pull down, affinity chromatography technology	Wen W (2010), Wen W (2010), Wen W (2010)	3
USP11	3	RNF2	1	affinity chromatography technology, pull down	Maertens GN (2010), Maertens GN (2010)	2
PPM1G	1	PARP1	3	affinity chromatography technology	St-Denis N (2016)	1
CSNK2A1	15	XRCC5	5	enzymatic study	Olsen BB (2010)	1
XRCC5	5	SSRP1	1	affinity chromatography technology, imaging technique	Sand-Dejmek J (2011), Sand-Dejmek J (2011)	2
RNF8	2	H2AFX	1	enzymatic study, enzymatic study, imaging technique	Mattiroli F (2012), Yu M (2016), Liang L (2017)	3
NBN	1	H2AFX	1	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Kobayashi J (2002), Kobayashi J (2002), Park JH (2006), Cheng WH (2005), Lukas C (2004), Kobayashi J (2002), Kobayashi J (2002), Pan MR (2011), Kobayashi J (2012)	9
TP53BP1	3	RNF8	2	imaging technique	Galanty Y (2009)	1
PARP1	3	BRCA1	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, genetic interference, genetic interference, affinity chromatography technology	Hu Y (2014), Hu Y (2014), Hu Y (2014), Shen JP (2017), Srivas R (2016), Ertych N (2016)	6
H2AFX	1	KAT5	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Heo K (2008), Heo K (2008), Heo K (2008), Lee HS (2010)	4
ATM	9	KAT5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sun Y (2009), Sun Y (2005), Sun Y (2005), Dittmann K (2011)	4
BRCA2	6	USP11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Schoenfeld AR (2004), Schoenfeld AR (2004), Schoenfeld AR (2004), Schoenfeld AR (2004)	4
KAT5	1	NBN	1	affinity chromatography technology	Chailleux C (2010)	1
PPM1G	1	XRCC6	3	affinity chromatography technology, bioid, affinity chromatography technology	Yadav L (2017), Yadav L (2017), Yadav L (2017)	3
XRCC5	5	SUPT16H	4	affinity chromatography technology, affinity chromatography technology	Sand-Dejmek J (2011), Sand-Dejmek J (2011)	2
XRCC5	5	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Wei L (2008), Wei L (2008), Jiang G (2013), Jiang G (2013), Jiang G (2013), Ertych N (2016)	6
H2AFX	1	SUPT16H	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Du YC (2006), Heo K (2008), Heo K (2008), Heo K (2008), Huttlin EL (2017)	5
H2AFX	1	PARP1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Du YC (2006), Du YC (2006), Heo K (2008), Heo K (2008), Heo K (2008), Yang X (2010), Yang X (2010), Huttlin EL (2017)	8
XRCC5	5	ATM	9	pull down	Falck J (2005)	1
PARP1	3	HIST1H4A	0	enzymatic study	Rajamohan SB (2009)	1
BMI1	0	SMARCA4	19	affinity chromatography technology	Cao Q (2014)	1
BMI1	0	NBN	1	affinity chromatography technology	Wei F (2015)	1
DHX9	3	XRCC6	3	affinity chromatography technology	Wang Q (2005)	1
ATM	9	TP53BP1	3	pull down, enzymatic study, enzymatic study	Fernandez-Capetillo O (2002), Ward IM (2003), Lee H (2009)	3
KAT5	1	MRE11	3	affinity chromatography technology	Chailleux C (2010)	1
BRCA1	7	NBN	1	biochemical, biochemical, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Zhong Q (1999), Shimada M (2009), Chen L (2008), Hill SJ (2014), Goldstein M (2015), Goldstein M (2015), Parameswaran B (2015)	9
DHX9	3	PRKDC	12	affinity chromatography technology, enzymatic study, biochemical	Mischo HE (2005), Mischo HE (2005), Mischo HE (2005)	3
CSNK2A1	15	XRCC6	3	enzymatic study	Olsen BB (2010)	1
USP11	3	XRCC5	5	affinity chromatography technology	Zhou Z (2017)	1
SSRP1	1	PARP1	3	affinity chromatography technology	Huttlin EL (2017)	1
SSRP1	1	HIST1H4A	0	pull down, affinity chromatography technology	Winkler DD (2011), Huttlin EL (2017)	2
PARP1	3	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Ju BG (2006), Galande S (1999), Galande S (1999), Galande S (1999), Idogawa M (2007), Li B (2004), Li B (2004), Yin H (2006), Yin H (2006), Wu T (2013), Huttlin EL (2017)	11
ATM	9	TRAF6	0	pull down	Hinz M (2010)	1
BRCA1	7	SUPT16H	4	genetic interference, imaging technique, affinity chromatography technology	Hill SJ (2014), Hill SJ (2014), Ertych N (2016)	3
TP53BP1	3	XRCC5	5	affinity chromatography technology	Woods NT (2012)	1
BMI1	0	KAT5	1	two hybrid	Stelzl U (2005)	1
NBN	1	MRE11	3	biochemical, affinity chromatography technology, biochemical, two hybrid, two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Cerosaletti KM (2003), Trujillo KM (1998), Matsuzaki K (2008), Desai-Mehta A (2001), Desai-Mehta A (2001), Desai-Mehta A (2001), Zheng L (2009), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Nakanishi K (2002), Shimada M (2009), Shimada M (2009), Yanagihara H (2011), Falck J (2005), Falck J (2005), Falck J (2005), Wu J (2012), Alt JR (2005), Havugimana PC (2012), Wijnhoven P (2015), Suhasini AN (2013), Suhasini AN (2013), Nicholson J (2017)	26
PARP1	3	PRKDC	12	affinity chromatography technology	Ju BG (2006)	1
WRAP53	1	MDC1	8	affinity chromatography technology, imaging technique, affinity chromatography technology	Henriksson S (2014), Rassoolzadeh H (2015), Rassoolzadeh H (2015)	3
H2AFX	1	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Mischo HE (2005), Mischo HE (2005), Heo K (2008), Heo K (2008), Heo K (2008), Lee HS (2010), Kobayashi J (2012), Huttlin EL (2017)	8
CSNK2A1	15	SUPT16H	4	biochemical, affinity chromatography technology, biochemical	Havugimana PC (2012), So J (2015), Wan C (2015)	3
H2AFX	1	XRCC5	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Heo K (2008), Heo K (2008), Sand-Dejmek J (2011)	3
KAT5	1	HIST1H4A	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Sun Y (2006), Faiola F (2005), Pasheva E (2004), Park JH (2010), Sun Y (2009), Ghizzoni M (2012), Koiwai K (2011)	7
H2AFX	1	SMARCA4	19	affinity chromatography technology, affinity chromatography technology, pull down	Park JH (2006), Lee HS (2010), Lee HS (2010)	3
KAT5	1	PRKDC	12	affinity chromatography technology, affinity chromatography technology	Jiang X (2006), Jiang X (2006)	2
RNF2	1	SMARCA4	19	affinity chromatography technology	Cao Q (2014)	1
H2AFX	1	BRCA2	6	affinity chromatography technology, affinity chromatography technology, pull down	Heo K (2008), Heo K (2008), Krum SA (2010)	3
BMI1	0	SUPT16H	4	affinity chromatography technology	Cao Q (2014)	1
STK4	1	HIST2H2BE	1	enzymatic study, enzymatic study, enzymatic study	Cheung WL (2003), Yuan Z (2010), Yun HJ (2011)	3
PRKDC	12	H2AFX	1	enzymatic study, enzymatic study, affinity chromatography technology, pull down, enzymatic study, enzymatic study	Park EJ (2003), Mischo HE (2005), Heo K (2008), Heo K (2008), Li A (2010), Kim K (2012)	6
PPM1D	11	H2AFX	1	enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Macurek L (2010), Cha H (2010), Moon SH (2010), Moon SH (2010), Moon SH (2010)	5
TP53BP1	3	XRCC6	3	affinity chromatography technology	Woods NT (2012)	1
DHX9	3	SSRP1	1	biochemical	Havugimana PC (2012)	1
ATM	9	H2AFX	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Tsai WB (2008), Tsai WB (2008), Dittmann K (2011), Pan MR (2011), Kim K (2012), Rezaeian AH (2017)	6
ATM	9	BMI1	0	affinity chromatography technology, affinity chromatography technology	Facchino S (2010), Pan MR (2011)	2
ATM	9	NBN	1	unspecified method, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim ST (1999), Wang Y (2000), Cariveau MJ (2007), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Wu J (2012), Wu J (2012), Wei F (2015)	12
DHX9	3	MRE11	3	biochemical	Kristensen AR (2012)	1
ILF2	3	MRE11	3	biochemical, affinity chromatography technology	Kristensen AR (2012), Karmakar S (2010)	2
RNF2	1	CALR	1	affinity chromatography technology	Cao Q (2014)	1
DHX9	3	BRCA1	7	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	Schlegel BP (2003), Anderson SF (1998), Anderson SF (1998), Ertych N (2016)	4
CSNK2A1	15	NPM1	0	enzymatic study	Zhang M (2011)	1
MDC1	8	MRE11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology	Xu X (2003), Xu X (2003), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Stewart GS (2003), Chapman JR (2008), Chapman JR (2008), Chapman JR (2008)	10
RNF2	1	SSRP1	1	affinity chromatography technology	Cao Q (2014)	1
WRAP53	1	H2AFX	1	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Henriksson S (2014), Rassoolzadeh H (2015), Rassoolzadeh H (2015), Rassoolzadeh H (2015)	4
BRCA1	7	XRCC6	3	affinity chromatography technology, affinity chromatography technology	Woods NT (2012), Ertych N (2016)	2
RNF2	1	SUPT16H	4	affinity chromatography technology	Cao Q (2014)	1
HIST1H4A	0	HIST2H2BE	1	pull down	Shiio Y (2003)	1
ATM	9	PARP1	3	pull down	Haince JF (2007)	1
TP53I3	1	TP53BP1	3	imaging technique	Lee JH (2010)	1
KAT5	1	BRCA1	7	two hybrid	Hill SJ (2014)	1
CSNK2A1	15	MDC1	8	enzymatic study	Chapman JR (2008)	1
PPM1G	1	XRCC5	5	affinity chromatography technology, bioid, affinity chromatography technology	Yadav L (2017), Yadav L (2017), Yadav L (2017)	3
TP53BP1	3	HIST1H4A	0	unspecified method, x-ray crystallography, pull down	Botuyan MV (2006), Botuyan MV (2006), Jacquet K (2016)	3
MDC1	8	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, imaging technique, imaging technique	Matsuoka S (2007), Strauss C (2011), Strauss C (2011), Stewart GS (2003), Lou Z (2003), Mok MT (2010), Au WW (2005)	7
H2AFX	1	MRE11	3	affinity chromatography technology, imaging technique, affinity chromatography technology	Lukas C (2004), Kobayashi J (2002), Kobayashi J (2002)	3
BRCA1	7	SMARCA4	19	affinity chromatography technology, pull down, biochemical, pull down, affinity chromatography technology, affinity chromatography technology	Hill DA (2004), Bochar DA (2000), Bochar DA (2000), Bochar DA (2000), Tu Z (2013), Ertych N (2016)	6