PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
SUZ12	0	HIST1H2BB	3	affinity chromatography technology	Cao Q (2014)	1
CHD3	19	HIST1H2BB	3	affinity chromatography technology	Klement K (2014)	1
H2AFY	1	APP	1	pull down	Olah J (2011)	1
HIST1H3A	3	H2AFY	1	imaging technique, affinity chromatography technology, affinity chromatography technology	Soldi M (2013), Sarma K (2014), Huttlin EL (2017)	3
FANCD2	3	HIST1H2BB	3	enzymatic study, pull down	Sato K (2012), Sato K (2012)	2
RPS6KA5	2	APP	1	pull down	Olah J (2011)	1
KAT2B	2	HIST1H4A	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study	Brackertz M (2006), Seo SB (2002), Ito K (2000), Kim JH (2002), Wong K (2005), Hoffmann A (2008), Shen M (2013), Zheng X (2013), Zheng X (2013), Yamaguchi Y (2004)	10
MCM2	3	HIST1H2AD	1	affinity chromatography technology	Drissi R (2015)	1
EP300	36	CDK1	0	affinity chromatography technology, enzymatic study	Wang SA (2014), Wang SA (2014)	2
CYLD	2	HIST1H4A	0	affinity chromatography technology	Elliott PR (2016)	1
TRIM25	5	H2AFY	1	affinity chromatography technology	Choudhury NR (2017)	1
HIST1H2BB	3	ERCC6	6	affinity chromatography technology, affinity chromatography technology, far western blotting	Citterio E (2000), Citterio E (2000), Citterio E (2000)	3
MCM2	3	HIST1H3A	3	affinity chromatography technology, affinity chromatography technology	Drissi R (2015), Huttlin EL (2017)	2
HIST1H3A	3	HIST1H2BB	3	affinity chromatography technology	Klement K (2014)	1
LUZP4	2	H2AFY	1	affinity chromatography technology	Viphakone N (2015)	1
HIST1H2BB	3	APP	1	pull down	Olah J (2011)	1
SFN	1	DYRK1A	36	affinity chromatography technology	Benzinger A (2005)	1
AKT1	1	IGSF8	1	affinity chromatography technology	Perez-Hernandez D (2013)	1
EP300	36	HIST1H2AB	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study	Kalkhoven E (2002), Seo SB (2002), Ogryzko VV (1996), Yamaguchi Y (2004), An W (2002), Delvecchio M (2013), Ji A (2003), Fu M (2005)	8
HIST1H3A	3	HIST1H2AB	0	affinity chromatography technology	Tropberger P (2013)	1
EID1	1	HIST1H4A	0	pull down, pull down	Bavner A (2002), Bavner A (2002)	2
CREBBP	29	DAXX	5	two hybrid, affinity chromatography technology	Kuo HY (2005), Kuo HY (2005)	2
IGSF8	1	HIST1H3E	0	affinity chromatography technology	Perez-Hernandez D (2013)	1
CYLD	2	HDAC6	0	affinity chromatography technology, pull down, affinity chromatography technology	Wickstroem SA (2010), Wickstroem SA (2010), Sun L (2010)	3
WDR4	4	HIST1H2BB	3	affinity chromatography technology	Cheng IC (2016)	1
AKT1	1	CREBBP	29	pull down, enzymatic study	Drendall CI (2010), Drendall CI (2010)	2
CBX2	0	CBX4	1	affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Vandamme J (2011)	2
AKT1	1	SFN	1	affinity chromatography technology, affinity chromatography technology	Calvo N (2010), Calvo N (2010)	2
TRIM25	5	SFN	1	affinity chromatography technology	Urano T (2002)	1
CYLD	2	LMNA	2	affinity chromatography technology	Elliott PR (2016)	1
CHD1L	5	HIST1H2BB	3	affinity chromatography technology	Gottschalk AJ (2009)	1
TRIM25	5	APP	1	affinity chromatography technology	Choudhury NR (2017)	1
FANCD2	3	MCM5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lossaint G (2013), Lossaint G (2013), Lossaint G (2013)	3
KAT2B	2	AKT1	1	enzymatic study, affinity chromatography technology	Sundaresan NR (2011), Sundaresan NR (2011)	2
DYRK1A	36	HIST1H4A	0	enzymatic study	Himpel S (2000)	1
CDK2	0	HIST1H2AB	0	enzymatic study	Chen M (2012)	1
HIST1H4A	0	PPM1G	1	biochemical	Kristensen AR (2012)	1
IGSF8	1	HIST1H2BB	3	affinity chromatography technology	Perez-Hernandez D (2013)	1
AKT1	1	HIST1H2BB	3	enzymatic study	Rane MJ (2005)	1
LMNA	2	KAT5	1	two hybrid	Stelzl U (2005)	1
LMNA	2	CD81	0	two hybrid	Dittmer TA (2014)	1
HIST1H4A	0	HIST1H2BB	3	affinity chromatography technology	Klement K (2014)	1
TRIM25	5	EP300	36	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
HIST1H4A	0	ERCC6	6	affinity chromatography technology, affinity chromatography technology, far western blotting	Citterio E (2000), Citterio E (2000), Citterio E (2000)	3
HIST1H3A	3	DAXX	5	affinity chromatography technology	Huttlin EL (2017)	1
ZNF746	0	CDK1	0	affinity chromatography technology	Kang H (2015)	1
WDR4	4	HIST1H4A	0	affinity chromatography technology	Cheng IC (2016)	1
EID1	1	HIST1H2BB	3	pull down	Bavner A (2002)	1
BMI1	0	LMNA	2	affinity chromatography technology	Abdouh M (2016)	1
KAT2B	2	HIST1H2AB	0	enzymatic study, enzymatic study	Seo SB (2002), Avvakumov N (2003)	2
CHD1L	5	SSRP1	1	affinity chromatography technology	Huttlin EL (2017)	1
LUZP4	2	HIST1H2AD	1	affinity chromatography technology	Viphakone N (2015)	1
MCM2	3	CHD3	19	affinity chromatography technology	Drissi R (2015)	1
HIST1H3E	0	MCM2	3	affinity chromatography technology, affinity chromatography technology	Campos EI (2015), Drissi R (2015)	2
CENPA	0	HIST1H4A	0	biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Obuse C (2004), Shuaib M (2010), Bassett EA (2012), Lacoste N (2014)	4
CDK2	0	HIST1H4A	0	enzymatic study	Yuan WC (2011)	1
DYRK1A	36	APP	1	pull down	Olah J (2011)	1
MCM2	3	TRIM25	5	affinity chromatography technology	Drissi R (2015)	1
KAT5	1	APP	1	two hybrid, fluorescent resonance energy transfe, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down	Sumioka A (2005), Kinoshita A (2002), von Rotz RC (2004), von Rotz RC (2004), von Rotz RC (2004), Cao X (2004), Li Q (2004), Olah J (2011)	8
HIST1H3A	3	FANCD2	3	pull down, enzymatic study, pull down	Sato K (2012), Sato K (2012), Sato K (2012)	3
CYLD	2	AKT1	1	enzymatic study, affinity chromatography technology	Yang WL (2013), Yang WL (2013)	2
HIST1H3E	0	HIST1H4A	0	affinity chromatography technology	Shuaib M (2010)	1
ICAM1	6	HIST1H3E	0	affinity chromatography technology	Perez-Hernandez D (2013)	1
HIST1H3A	3	ERCC6	6	affinity chromatography technology, affinity chromatography technology, far western blotting	Citterio E (2000), Citterio E (2000), Citterio E (2000)	3
EP300	36	KAT2B	2	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Kim JH (2011), Lee M (2010), Santos-Rosa H (2003), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996), Mizuguchi Y (2012)	8
HIST1H4A	0	DAXX	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Saade E (2009), Saade E (2009), Hollenbach AD (2002), Huttlin EL (2017)	4
CENPA	0	HIST1H2BB	3	affinity chromatography technology, affinity chromatography technology	Shuaib M (2010), Lacoste N (2014)	2
CDK2	0	LMNA	2	affinity chromatography technology	Neganova I (2011)	1
CBX4	1	HIST1H2AB	0	affinity chromatography technology	Vandamme J (2011)	1
HIST1H2AA	1	HIST1H2BB	3	biochemical	Havugimana PC (2012)	1
CREBBP	29	HIST1H3A	3	enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Senyuk V (2005), Perissi V (1999), Pasheva E (2004), Shen WF (2001), Kouskouti A (2005), Kouskouti A (2005), Yasuda J (2004), Tropberger P (2013), Das C (2009)	9
EP300	36	MCM2	3	pull down	Karmakar S (2010)	1
TRIM25	5	CD81	0	affinity chromatography technology	Choudhury NR (2017)	1
RPS6KA5	2	HIST1H2BB	3	enzymatic study	New L (1999)	1
SFN	1	CDK1	0	affinity chromatography technology	Chan TA (1999)	1
MCM2	3	SFN	1	affinity chromatography technology	Drissi R (2015)	1
MCM2	3	HDAC6	0	affinity chromatography technology	Drissi R (2015)	1
CDK2	0	CREBBP	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
BMI1	0	HIST1H2BB	3	affinity chromatography technology	Cao Q (2014)	1
AKT1	1	CD81	0	affinity chromatography technology, affinity chromatography technology	Perez-Hernandez D (2013), Perez-Hernandez D (2013)	2
TRIM25	5	DHX9	3	affinity chromatography technology	Choudhury NR (2017)	1
EP300	36	HDAC6	0	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Han Y (2009), Han Y (2009), Liu Y (2012), Kirilyuk A (2012), Girdwood D (2003)	5
PHF6	1	CHD3	19	affinity chromatography technology	Todd MA (2012)	1
HIST1H3E	0	HIST1H2AB	0	affinity chromatography technology	Shuaib M (2010)	1
BMI1	0	HIST1H2AB	0	affinity chromatography technology	Abdouh M (2016)	1
EID1	1	HIST1H3A	3	pull down	Bavner A (2002)	1
USP3	1	HIST1H2BB	3	affinity chromatography technology	Nicassio F (2007)	1
ZNF746	0	DHX9	3	affinity chromatography technology	Kang H (2015)	1
DAXX	5	HIST1H2BB	3	affinity chromatography technology	Hein MY (2015)	1
BAZ1A	5	HIST1H3A	3	affinity chromatography technology	Klement K (2014)	1
KAT2B	2	HIST1H3A	3	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, imaging technique, enzymatic study, enzymatic study	Brackertz M (2006), Seo SB (2002), Pasheva E (2004), Kouskouti A (2005), Kiernan RE (1999), Wong K (2005), Hoffmann A (2008), Shen M (2013), Yamaguchi Y (2004), Tropberger P (2013)	10
KAT5	1	HIST1H3A	3	enzymatic study	Park JH (2010)	1
CDK1	0	HIST1H2AB	0	enzymatic study	Chen M (2012)	1
BMI1	0	TRIM25	5	affinity chromatography technology	Cao Q (2014)	1
ZNF746	0	TRIM25	5	affinity chromatography technology	Kang H (2015)	1
MCM2	3	HIST1H2AB	0	affinity chromatography technology	Drissi R (2015)	1
HIST1H2AB	0	ERCC6	6	affinity chromatography technology, affinity chromatography technology, far western blotting	Citterio E (2000), Citterio E (2000), Citterio E (2000)	3
USP16	0	HIST1H2BB	3	enzymatic study	Xu Y (2013)	1
CDK2	0	DHX9	3	affinity chromatography technology	Neganova I (2011)	1
MCM5	1	HIST1H2AD	1	affinity chromatography technology	Drissi R (2015)	1
EP300	36	HIST1H2BB	3	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study	Kalkhoven E (2002), Seo SB (2002), Ogryzko VV (1996), Yamaguchi Y (2004), An W (2002), Delvecchio M (2013), Ji A (2003), Fu M (2005)	8
CDK2	0	CDK1	0	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Huttlin EL (2017)	2
ICAM1	6	HIST1H2BB	3	affinity chromatography technology	Perez-Hernandez D (2013)	1
IGSF8	1	MCM5	1	affinity chromatography technology	Perez-Hernandez D (2013)	1
EP300	36	MCM5	1	pull down	Karmakar S (2010)	1
CREBBP	29	KAT5	1	affinity chromatography technology	Col E (2005)	1
RPS6KA5	2	EP300	36	affinity chromatography technology	Janknecht R (2003)	1
BMI1	0	CREBBP	29	affinity chromatography technology	Cao Q (2014)	1
MCM5	1	HIST1H2AA	1	affinity chromatography technology	Drissi R (2015)	1
HIST1H3E	0	LMNA	2	biochemical	Campos EI (2015)	1
CBX2	0	HIST1H2AB	0	affinity chromatography technology	Vandamme J (2011)	1
CDK2	0	HIST1H2BB	3	enzymatic study	Chen M (2012)	1
KAT2B	2	HIST1H2BB	3	enzymatic study	Seo SB (2002)	1
HIST1H3A	3	SSRP1	1	pull down, affinity chromatography technology	Kouskouti A (2005), Huttlin EL (2017)	2
CREBBP	29	HIST1H2BB	3	enzymatic study	Yasuda J (2004)	1
LUZP4	2	HIST1H2BB	3	affinity chromatography technology	Viphakone N (2015)	1
HIST1H3E	0	HIST1H2BB	3	affinity chromatography technology	Shuaib M (2010)	1
MCM2	3	DHX9	3	affinity chromatography technology	Drissi R (2015)	1
BMI1	0	CBX2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Maertens GN (2009), Gao Z (2012), Gao Z (2012), Gao Z (2012), Vandamme J (2011), Cao Q (2014), Hauri S (2016)	7
HDAC6	0	KAT5	1	affinity chromatography technology	Chen PB (2013)	1
FANCD2	3	KAT5	1	two hybrid, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Hejna J (2008), Hejna J (2008), Hejna J (2008), Hejna J (2008), Hejna J (2008)	5
FANCD2	3	HIST1H2AB	0	enzymatic study, pull down	Sato K (2012), Sato K (2012)	2
TRIM25	5	DYRK1A	36	affinity chromatography technology	Choudhury NR (2017)	1
AKT1	1	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Lin WN (2008), Lee IT (2010), Sundaresan NR (2011), Howie HL (2011), Chen J (2004), Chen J (2004)	6
DYRK1A	36	CREBBP	29	affinity chromatography technology	Varjosalo M (2013)	1
CDK2	0	MCM2	3	enzymatic study, affinity chromatography technology	Montagnoli A (2006), Neganova I (2011)	2
CBX2	0	HIST1H2BB	3	affinity chromatography technology	Vandamme J (2011)	1
SUZ12	0	TRIM25	5	affinity chromatography technology, affinity chromatography technology	Cao Q (2014), Choudhury NR (2017)	2
WDR4	4	HIST1H2AB	0	affinity chromatography technology	Cheng IC (2016)	1
MCM5	1	APP	1	pull down	Olah J (2011)	1
CBX4	1	HIST1H2BB	3	affinity chromatography technology	Vandamme J (2011)	1
CENPA	0	HIST1H2AB	0	affinity chromatography technology, affinity chromatography technology	Shuaib M (2010), Lacoste N (2014)	2
HDAC6	0	HIST1H2BB	3	affinity chromatography technology	Watson GW (2016)	1
CDK1	0	HDAC6	0	affinity chromatography technology	Galindo-Moreno M (2017)	1
BAZ1A	5	HIST1H2BB	3	affinity chromatography technology	Klement K (2014)	1
HIST1H3A	3	HIST1H4A	0	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down	Tagami H (2004), Shiio Y (2003), Zippo A (2009), Soldi M (2013), Klement K (2014), Sato K (2012)	6
HIST1H3A	3	HDAC6	0	pull down	Li X (2014)	1
SFN	1	HIST1H2BB	3	affinity chromatography technology	Wilker EW (2007)	1
CDK1	0	HIST1H4A	0	enzymatic study	Yuan WC (2011)	1
EP300	36	HIST1H3A	3	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Liu B (2009), Brackertz M (2006), Faiola F (2005), Daujat S (2002), Kalkhoven E (2002), Seo SB (2002), Kim JH (2005), Bordoli L (2001), Kim MY (2001), Kutney SN (2004), Wang F (2010), Loven MA (2004), Kiernan RE (1999), Wong K (2005), Ogryzko VV (1996), Yamaguchi Y (2004), Furumatsu T (2005), An W (2002), Delvecchio M (2013), Delvecchio M (2013), Tropberger P (2013), Das C (2009), Shimura M (2011), Ji A (2003), Fu M (2005), Suganuma T (2002), Tang Z (2013), Kim JH (2006), Lopes da Rosa J (2013), Li X (2014), Wang YL (2008), Du C (2017), Yi P (2017), Wan W (2017)	34
LMNA	2	SSRP1	1	affinity chromatography technology	Depreux FF (2015)	1
HIST1H3A	3	CHD3	19	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wysocka J (2006), Nishioka K (2002), Klement K (2014)	3
CDK1	0	USP16	0	enzymatic study, enzymatic study	Xu Y (2013), Zhuo X (2015)	2
CD81	0	HIST1H3E	0	affinity chromatography technology	Perez-Hernandez D (2013)	1
CD81	0	IGSF8	1	affinity chromatography technology	Clark KL (2001)	1
HIST1H4A	0	FANCD2	3	pull down, enzymatic study, pull down	Sato K (2012), Sato K (2012), Sato K (2012)	3
CENPA	0	HIST1H3E	0	affinity chromatography technology	Foltz DR (2006)	1
CDK1	0	HIST1H2BB	3	enzymatic study	Chen M (2012)	1
MCM2	3	HIST1H2AA	1	affinity chromatography technology	Drissi R (2015)	1
DYRK1A	36	EP300	36	affinity chromatography technology	Varjosalo M (2013)	1
HIST1H2BB	3	SSRP1	1	biochemical	Havugimana PC (2012)	1
CDK1	0	KAT5	1	enzymatic study	Lemercier C (2003)	1
CYLD	2	MCM5	1	affinity chromatography technology	Elliott PR (2016)	1
TRIM25	5	CDK1	0	affinity chromatography technology	Choudhury NR (2017)	1
EID1	1	CREBBP	29	affinity chromatography technology, biochemical, affinity chromatography technology, pull down	Ye B (2013), Ye B (2013), Bavner A (2005), Bavner A (2005)	4
MCM2	3	HIST1H2BB	3	affinity chromatography technology	Drissi R (2015)	1
BMI1	0	HIST1H3A	3	affinity chromatography technology	Abdouh M (2016)	1
DYRK1A	36	HIST1H2BB	3	enzymatic study	Himpel S (2000)	1
SSRP1	1	HIST1H4A	0	pull down, affinity chromatography technology	Winkler DD (2011), Huttlin EL (2017)	2
BAZ1A	5	HIST1H4A	0	affinity chromatography technology	Klement K (2014)	1
MCM2	3	APP	1	pull down	Olah J (2011)	1
BMI1	0	H2AFY	1	affinity chromatography technology	Cao Q (2014)	1
DOT1L	7	HIST1H2BB	3	affinity chromatography technology	Park G (2010)	1
USP3	1	HIST1H2AB	0	affinity chromatography technology	Nicassio F (2007)	1
CREBBP	29	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Crusselle-Davis VJ (2007), Dohda T (2004), Dohda T (2004)	3
HIST1H3E	0	SSRP1	1	affinity chromatography technology	Campos EI (2015)	1
TRIM25	5	WDR4	4	affinity chromatography technology	Choudhury NR (2017)	1
AKT1	1	FANCD2	3	affinity chromatography technology	Zhang X (2016)	1
MCM5	1	DHX9	3	affinity chromatography technology	Drissi R (2015)	1
PPM1G	1	HIST1H2BB	3	affinity chromatography technology	St-Denis N (2016)	1
BMI1	0	KAT5	1	two hybrid	Stelzl U (2005)	1
H2AFY	1	HIST1H2AB	0	affinity chromatography technology	Sarma K (2014)	1
SSRP1	1	MCM5	1	affinity chromatography technology, affinity chromatography technology	Tan BC (2006), OConnell BC (2010)	2
HIST1H3A	3	CBX2	0	bioid	Lambert JP (2015)	1
EP300	36	EID1	1	pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, biochemical	Miyake S (2000), MacLellan WR (2000), MacLellan WR (2000), Bavner A (2002), Ye B (2013), Ye B (2013)	6
DHX9	3	HIST1H2BB	3	biochemical	Havugimana PC (2012)	1
KAT5	1	HIST1H4A	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Sun Y (2006), Faiola F (2005), Pasheva E (2004), Park JH (2010), Sun Y (2009), Ghizzoni M (2012), Koiwai K (2011)	7
AKT1	1	APP	1	pull down	Olah J (2011)	1
HIST1H3E	0	HIST1H2AA	1	affinity chromatography technology	Campos EI (2015)	1
TRIM25	5	CREBBP	29	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
HIST1H3E	0	MCM5	1	affinity chromatography technology	Campos EI (2015)	1
KAT5	1	HIST1H2BB	3	affinity chromatography technology	Jacquet K (2016)	1
BMI1	0	CHD3	19	affinity chromatography technology	Cao Q (2014)	1
BMI1	0	BAZ1A	5	affinity chromatography technology	Abdouh M (2016)	1
HIST1H3A	3	USP3	1	bioid	Lambert JP (2015)	1
MCM5	1	HIST1H3A	3	affinity chromatography technology	Drissi R (2015)	1
TRIM25	5	CHD3	19	affinity chromatography technology	Choudhury NR (2017)	1
PPM1G	1	HIST1H2AB	0	affinity chromatography technology, bioid	Yadav L (2017), Yadav L (2017)	2
CD81	0	HIST1H2BB	3	affinity chromatography technology	Perez-Hernandez D (2013)	1
SUZ12	0	H2AFY	1	affinity chromatography technology	Cao Q (2014)	1
SSRP1	1	MCM2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tan BC (2006), OConnell BC (2010), Huttlin EL (2017)	3
RPS6KA5	2	CREBBP	29	affinity chromatography technology	Janknecht R (2003)	1
EP300	36	KAT5	1	affinity chromatography technology, affinity chromatography technology	Col E (2005), Col E (2005)	2
DOT1L	7	HIST1H2AA	1	affinity chromatography technology	Park G (2010)	1
DHX9	3	SSRP1	1	biochemical	Havugimana PC (2012)	1
CYLD	2	HIST1H2BB	3	affinity chromatography technology	Elliott PR (2016)	1
KAT5	1	HIST1H2AB	0	enzymatic study	Jacquet K (2016)	1
MBTD1	1	HIST1H2BB	3	affinity chromatography technology	Jacquet K (2016)	1
BMI1	0	PHF6	1	affinity chromatography technology	Cao Q (2014)	1
CD81	0	MCM5	1	affinity chromatography technology	Perez-Hernandez D (2013)	1
CREBBP	29	KAT2B	2	pull down, biochemical, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Tini M (2002), Cho H (1998), Cho H (1998), Cho H (1998), Korzus E (1998), Korzus E (1998), Korzus E (1998), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996)	10
CYLD	2	DHX9	3	affinity chromatography technology	Elliott PR (2016)	1
CENPA	0	SSRP1	1	affinity chromatography technology, affinity chromatography technology	Foltz DR (2006), Huttlin EL (2017)	2
PHF6	1	HIST1H2BB	3	affinity chromatography technology	Todd MA (2012)	1
HIST1H2AB	0	HIST1H2BB	3	pull down	Sato K (2012)	1
HIST1H4A	0	MCM5	1	affinity chromatography technology, affinity chromatography technology	Saade E (2009), Drissi R (2015)	2
MBTD1	1	HIST1H4A	0	pull down	Jacquet K (2016)	1
CENPA	0	H2AFY	1	biochemical, affinity chromatography technology, affinity chromatography technology	Obuse C (2004), Foltz DR (2006), Huttlin EL (2017)	3
FANCD2	3	MCM2	3	imaging technique, affinity chromatography technology, affinity chromatography technology	Panneerselvam J (2014), Lossaint G (2013), Lossaint G (2013)	3
CENPA	0	HIST1H2AD	1	biochemical	Obuse C (2004)	1
TRIM25	5	LMNA	2	affinity chromatography technology	Choudhury NR (2017)	1
H2AFY	1	HIST1H4A	0	affinity chromatography technology	Sarma K (2014)	1
LMNA	2	PPM1G	1	bioid	Roux KJ (2012)	1
LMNA	2	HIST1H3A	3	affinity chromatography technology	Depreux FF (2015)	1
SUZ12	0	DHX9	3	affinity chromatography technology	Cao Q (2014)	1
EP300	36	HIST1H4A	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Brackertz M (2006), Faiola F (2005), Kalkhoven E (2002), Seo SB (2002), Kim JH (2005), Bordoli L (2001), Kim MY (2001), Kutney SN (2004), Deng L (2001), Wang F (2010), Ghizzoni M (2012), Loven MA (2004), Wong K (2005), Murakami M (2005), Ogryzko VV (1996), Yamaguchi Y (2004), Saha RN (2007), Furumatsu T (2005), An W (2002), Delvecchio M (2013), Dornan D (2003), Ji A (2003), Fu M (2005), Suganuma T (2002), Kim JH (2006), Lopes da Rosa J (2013), Wright DG (2016), Du C (2017), Yi P (2017)	29
USP16	0	HIST1H2AB	0	enzymatic study	Xu Y (2013)	1
MCM5	1	MCM2	3	two hybrid, two hybrid, affinity chromatography technology, biochemical, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), DaFonseca CJ (2001), Havugimana PC (2012), Ramachandran N (2004), Wan C (2015), Drissi R (2015), Drissi R (2015), Huang J (2013), Lossaint G (2013)	10
RNF20	9	HIST1H2BB	3	enzymatic study	Kim J (2009)	1
KAT5	1	MBTD1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Jacquet K (2016), Jacquet K (2016), Jacquet K (2016), Huttlin EL (2017)	5
CREBBP	29	HIST1H4A	0	enzymatic study, enzymatic study, enzymatic study	Perissi V (1999), Pasheva E (2004), Yasuda J (2004)	3
DYRK1A	36	HIST1H3A	3	enzymatic study	Himpel S (2000)	1
EP300	36	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Felzien LK (1999), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
LMNA	2	H2AFY	1	bioid, affinity chromatography technology	Roux KJ (2012), Depreux FF (2015)	2
RPS6KA5	2	HIST1H3E	0	enzymatic study	Zhang Y (2004)	1
BMI1	0	EP300	36	affinity chromatography technology	Cao Q (2014)	1
ZNF746	0	HIST1H2BB	3	affinity chromatography technology	Kang H (2015)	1
LMNA	2	HIST1H2BB	3	affinity chromatography technology	Depreux FF (2015)	1
LUZP4	2	HIST1H4A	0	affinity chromatography technology	Viphakone N (2015)	1
CENPA	0	BMI1	0	biochemical	Obuse C (2004)	1
MCM2	3	HIST1H4A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Saade E (2009), Saade E (2009), Saade E (2009), Drissi R (2015), Huttlin EL (2017)	5
CBX4	1	BMI1	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xia ZB (2003), Satijn DP (1997), Satijn DP (1997), Aoto T (2008), Maertens GN (2009), Gao Z (2012), Gao Z (2012), Vandamme J (2011), Cao Q (2014), Hein MY (2015), Sanchez A (2016), Hauri S (2016), Hauri S (2016)	13
MCM5	1	HIST1H2BB	3	affinity chromatography technology	Drissi R (2015)	1
H2AFY	1	HIST1H2BB	3	affinity chromatography technology	Sarma K (2014)	1
KAT2B	2	ERCC6	6	affinity chromatography technology, affinity chromatography technology, imaging technique	Shen M (2013), Shen M (2013), Shen M (2013)	3
MCM2	3	LMNA	2	affinity chromatography technology	Drissi R (2015)	1
TRIM25	5	HIST1H2BB	3	affinity chromatography technology	Choudhury NR (2017)	1
HIST1H2AD	1	HIST1H2BB	3	biochemical	Havugimana PC (2012)	1
KAT2B	2	CDK2	0	pull down, affinity chromatography technology, enzymatic study	Mateo F (2009), Mateo F (2009), Mateo F (2009)	3
MCM5	1	HIST1H2AB	0	affinity chromatography technology	Drissi R (2015)	1
MCM5	1	LMNA	2	affinity chromatography technology, two hybrid	Drissi R (2015), Dittmer TA (2014)	2