PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
HSPA5	0	STIP1	1	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
PON2	0	SIL1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CBL	7	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Valiya Veettil M (2011), Brehme M (2009)	2
EGFR	5	OS9	4	affinity chromatography technology	Foerster S (2013)	1
SQSTM1	0	ID2	0	affinity chromatography technology	Li X (2017)	1
PRSS50	0	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HSPA8	4	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Du C (2017), Du C (2017)	3
AIRE	3	RUVBL2	4	affinity chromatography technology	Abramson J (2010)	1
EGFR	5	HSPA5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lavictoire SJ (2003), Foerster S (2013), Li J (2013), Yao Z (2017)	4
PON2	0	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GPX7	0	DNAJB11	3	affinity chromatography technology	Wei PC (2012)	1
SQSTM1	0	PAWR	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Chang S (2002), Chang S (2002), Chang S (2002), Chang S (2002)	4
HSPA1A	0	HSPA8	4	biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012)	2
SNW1	0	HNRNPU	12	affinity chromatography technology, affinity chromatography technology	Zhang C (2003), Lleres D (2010)	2
EGFR	5	STIP1	1	protein complementation assay	Deribe YL (2009)	1
RAF1	3	HSPA8	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Giommarelli C (2010), Zhu J (2005), Zhu J (2005), Zhu J (2005)	4
HSPA5	0	SIL1	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Chung KT (2002), Chung KT (2002), Williams JM (2015), Huttlin EL (2017)	4
HSPA5	0	HNRNPU	12	affinity chromatography technology, biochemical	Li J (2013), Wan C (2015)	2
EIF2AK3	3	HSPA5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ma K (2002), Rao R (2010), Zhu X (2016)	3
AMFR	2	ERLIN2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jo Y (2011), Jo Y (2011), Jo Y (2011), Pearce MM (2007), Huber MD (2013), Christianson JC (2012)	6
UBL4A	0	HNRNPU	12	affinity chromatography technology	Xu Y (2012)	1
GRB2	2	CLU	1	two hybrid	Wang J (2008)	1
EGFR	5	DNAJB11	3	affinity chromatography technology	Tong J (2014)	1
HSPA5	0	FUS	0	affinity chromatography technology, affinity chromatography technology	Li J (2013), Wang T (2014)	2
RUVBL2	4	HNRNPU	12	affinity chromatography technology	Jeronimo C (2007)	1
BRAF	12	EGFR	5	genetic interference	Shen JP (2017)	1
EGFR	5	YWHAB	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
EGFR	5	HSP90B1	3	protein complementation assay, affinity chromatography technology, affinity chromatography technology	Deribe YL (2009), Lavictoire SJ (2003), Yao Z (2017)	3
AIRE	3	HSPA8	4	affinity chromatography technology	Fogeron ML (2013)	1
GRB2	2	EP300	36	two hybrid	Bandyopadhyay S (2010)	1
UBQLN4	2	RPN1	2	two hybrid	Lim J (2006)	1
CBL	7	HSPA1L	2	affinity chromatography technology	Brehme M (2009)	1
ERLEC1	1	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Christianson JC (2008), Yanagisawa K (2010)	2
HNRNPU	12	HNRNPA1	1	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Roy R (2014), Hein MY (2015), Hein MY (2015)	5
METTL21A	0	HSPA1L	2	affinity chromatography technology	Cloutier P (2013)	1
GRB2	2	PON2	0	two hybrid	Wang J (2011)	1
LDLR	4	HSP90B1	3	affinity chromatography technology	Sorensen S (2006)	1
PAWR	2	HSPA5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Burikhanov R (2009), Burikhanov R (2009), Burikhanov R (2009)	3
SNW1	0	RUVBL2	4	affinity chromatography technology	Lleres D (2010)	1
SQSTM1	0	HDAC6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tanji K (2012), Yan J (2013), Yan J (2013), Chen Q (2015)	4
YWHAB	1	HSPA5	0	affinity chromatography technology, biochemical	Jin J (2004), Havugimana PC (2012)	2
AIRE	3	HSPA1A	0	affinity chromatography technology	Fogeron ML (2013)	1
EGFR	5	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ettenberg SA (1999), Tvorogov D (2002), Pennock S (2008), Umebayashi K (2008), Ng C (2008), Ng C (2008), Povlsen GK (2008), Khan EM (2008), Su X (2007), Shtiegman K (2007), Han W (2006), Visser GD (2005), Tsacoumangos A (2005), Prasad NK (2005), Gur G (2004), Kowanetz K (2004), Feshchenko EA (2004), Wu WJ (2003), Schmidt MH (2003), Bao J (2003), Rubin C (2003), Waterman H (1999), Bonaccorsi L (2007), Dey N (2011), Miraoui H (2010), Guo HB (2009), Tong J (2009), Tong J (2009), Sun Q (2010), Sanada F (2009), Rafiq K (2011), Ravid T (2004), Ravid T (2004), Duan L (2011), Duan L (2011), Haglund K (2005), Oksvold MP (2003), Oksvold MP (2003), Gui A (2012), Yang S (2006), de Melker AA (2004), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Raguz J (2007), de Melker AA (2004), Thien CB (2001), Kassenbrock CK (2004), Tarcic G (2009), Schroeder B (2012), Adachi S (2009), Shen F (2007), Mitsushima M (2006), Choi JH (2003), Burke P (2001), Tanaka S (1995), Meisner H (1995), Meisner H (1995), Kumar EA (2012), Tong J (2008), Dou H (2012), Levkowitz G (1999), Levkowitz G (1999), Bode AM (2009), Thomas C (2012), Meijer IM (2013), Chang CC (2012), Chang CC (2012), Smith CJ (2013), Gan Y (2010), Scott RP (2005), Fukazawa T (1996), Fukazawa T (1996), Fukazawa T (1996), Wang L (2013), Hong SY (2013), Sigismund S (2013), Sigismund S (2013), Sigismund S (2013), Meisner H (1997), Odintsova E (2013), Kondratov KA (2010), He Z (2014), Tong J (2014), Balaji K (2012), Kiuchi T (2014), Zhang B (2005), Waterman H (1999), Ha Thi HT (2015), Yao S (2015), Kortuem F (2015), Igloi Z (2015), Song F (2016), Song F (2016), Lin TY (2017), Conte A (2017)	96
CBL	7	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jain SK (1997), Liu SK (1998), Ettenberg SA (1999), Wong A (2002), Wong A (2002), Robertson H (1997), Donovan JA (1994), Park RK (1999), Erdreich-Epstein A (1999), Gesbert F (1998), Gesbert F (1998), Gesbert F (1998), Husson H (1997), Saci A (2002), Odai H (1997), Ng C (2008), Khan EM (2008), Bandyopadhyay S (2010), Jiang X (2003), Waterman H (2002), Miraoui H (2010), Ravid T (2004), Ingham RJ (1996), Erdreich-Epstein A (1997), Rellahan BL (2003), Izadi KD (1998), Wang Y (1999), Chu J (1998), Bonita DP (1997), Boussiotis VA (1997), Meisner H (1995), Meisner H (1995), Barber DL (1997), Shishido T (2000), Bartkiewicz M (1999), Buday L (1996), Tarcic G (2009), Belleudi F (2007), Brizzi MF (1996), Brenner B (2001), Donovan JA (1996), Donovan JA (1996), Donovan JA (1996), Gaston I (2004), Gaston I (2004), Tsygankov AY (1996), Tsygankov AY (1996), Hunter S (1997), Jain SK (1997), Levkowitz G (1996), Liu YC (1997), Odai H (1995), Odai H (1995), Meisner H (1995), Huang JY (2000), Panchamoorthy G (1996), Panchamoorthy G (1996), Yokouchi M (1997), Oda A (1996), Fukazawa T (1995), Fukazawa T (1995), Selbach M (2006), Brehme M (2009), Brehme M (2009), Fukazawa T (1995), Cerboni C (1998), Cerboni C (1998), Fixman ED (1997), Anderson SM (1997), Houtman JC (2006), Brizzi MF (1996), Scott RP (2005), Scott RP (2005), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Umehara H (2002), Taipale M (2014), Taipale M (2014), Grossmann A (2015), Grossmann A (2015), Igloi Z (2015), Huttlin EL (2017)	83
CBL	7	HSPA8	4	affinity chromatography technology	Brehme M (2009)	1
UBQLN4	2	GPX7	0	two hybrid	Lim J (2006)	1
EGFR	5	CLU	1	affinity chromatography technology	Tong J (2014)	1
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
SPACA4	0	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FUS	0	HNRNPA3	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
HNRNPA1	1	FUS	0	affinity chromatography technology	Roy R (2014)	1
BRAF	12	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Gloeckner CJ (2007), Eisenhardt AE (2016)	2
CDH1	4	EP300	36	affinity chromatography technology, affinity chromatography technology	Turnell AS (2005), Turnell AS (2005)	2
EGFR	5	HSPA1A	0	protein complementation assay, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Deribe YL (2009), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013)	5
AMFR	2	HSPA5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jo Y (2011), Chang YW (2014), Chang YW (2014), Chang YW (2015), Chang YW (2015)	5
CDH1	4	YWHAB	1	bioid	Guo Z (2014)	1
AMFR	2	UBL4A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Wang Q (2011), Wang Q (2011), Liu Y (2014), Liu Y (2014)	4
HSPA5	0	HSPA1L	2	biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012)	2
GRB2	2	FUS	0	affinity chromatography technology	Brehme M (2009)	1
EP300	36	HDAC6	0	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Han Y (2009), Han Y (2009), Liu Y (2012), Kirilyuk A (2012), Girdwood D (2003)	5
HDAC6	0	FUS	0	affinity chromatography technology	Watson GW (2016)	1
EGFR	5	RAF1	3	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
RUVBL2	4	UCHL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Cai Y (2007), Yao T (2008), Huttlin EL (2017)	4
HSPA5	0	RAF1	3	pull down, affinity chromatography technology, affinity chromatography technology	Shu CW (2008), Shu CW (2008), Shu CW (2008)	3
WNT4	0	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FBLN7	4	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ERLEC1	1	HSP90B1	3	affinity chromatography technology, affinity chromatography technology	Christianson JC (2008), Christianson JC (2008)	2
GPX7	0	HSPA5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wei PC (2012), Wei PC (2012), Wei PC (2012)	3
TOR3A	0	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ID2	0	HSPA1L	2	affinity chromatography technology	Lee SB (2016)	1
METTL21A	0	HSPA5	0	affinity chromatography technology, enzymatic study	Cloutier P (2013), Cloutier P (2013)	2
ID2	0	HSPA8	4	affinity chromatography technology	Lee SB (2016)	1
CDH1	4	HSPA8	4	affinity chromatography technology, bioid	Catimel B (2005), Guo Z (2014)	2
EGFR	5	HDAC6	0	affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Gao YS (2010), Deribe YL (2009), Deribe YL (2009), Deribe YL (2009), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	7
SNW1	0	HSPA8	4	affinity chromatography technology	Lleres D (2010)	1
BRAF	12	HSPA8	4	affinity chromatography technology	Gloeckner CJ (2007)	1
DNAJB11	3	UBQLN4	2	two hybrid	Vinayagam A (2011)	1
UBL4A	0	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Xu Y (2012), Hein MY (2015)	2
EGFR	5	RUVBL2	4	affinity chromatography technology	Yao Z (2017)	1
EGFR	5	FUS	0	affinity chromatography technology	Liccardi G (2014)	1
EGFR	5	FBLN7	4	affinity chromatography technology	Yao Z (2017)	1
UBL4A	0	HSPA1L	2	affinity chromatography technology	Xu Y (2012)	1
CLU	1	HSPA5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang C (2013), Li N (2013), Li N (2013)	3
HSPA5	0	DNAJB11	3	affinity chromatography technology, pull down, affinity chromatography technology, biochemical, pull down, affinity chromatography technology	Li J (2013), Marcinowski M (2011), Huttlin EL (2015), Wan C (2015), Schorr S (2015), Huttlin EL (2017)	6
GRB2	2	YWHAB	1	affinity chromatography technology	Bisson N (2011)	1
AMFR	2	OS9	4	affinity chromatography technology	Zhang T (2015)	1
CCNJL	3	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DNAJB11	3	HSPA8	4	biochemical, affinity chromatography technology	Wan C (2015), Lau PP (2001)	2
GRB2	2	HNRNPU	12	affinity chromatography technology	Brehme M (2009)	1
DNAJB11	3	HSPA1A	0	affinity chromatography technology	Lau PP (2001)	1
HSP90B1	3	RPN1	2	biochemical	Wan C (2015)	1
HSPA5	0	DNAJC10	3	pull down, affinity chromatography technology, affinity chromatography technology	Cunnea PM (2003), Dong M (2008), Li J (2013)	3
TP53	0	EP300	36	pull down, genetic interference, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, x-ray crystallography, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, unspecified method, affinity chromatography technology, enzymatic study, unspecified method, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, unspecified method	An W (2004), Pastorcic M (2000), Livengood JA (2002), Livengood JA (2002), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Tang Y (2008), Wang H (2008), Valbuena A (2008), Shi D (2009), Vega FM (2004), Finlan L (2004), Groenroos E (2004), Zhao Y (2006), Roe JS (2006), Pedeux R (2005), Sekaric P (2007), Pan X (2009), Tang Y (2006), Sen GS (2011), Li Y (2012), Li Y (2012), Gillotin S (2010), Grossman SR (2003), Issaeva N (2004), Kitagawa M (2008), Sabbatini P (2002), Burge S (2009), Zilfou JT (2001), Issaeva N (2004), Issaeva N (2004), Feng H (2009), Feng H (2009), Lill NL (1997), Dornan D (2004), Dornan D (2004), Di Agostino S (2006), Wells M (2008), Fath DM (2006), Kobet E (2000), Costanzo A (2002), Kumazawa T (2011), Borger DR (2006), Cui D (2013), Borger DR (2006), Lee SJ (2013), Tang HY (2006), Lin C (2011), Choi WI (2014), Ding G (2013), Kim MK (2013), Ali A (2013), Wu G (2014), Mizuguchi Y (2012), Sinha S (2012), Sinha S (2012), Her YR (2013), Her YR (2013), Wu SY (2009), Wu SY (2009), Liu L (1999), Sakaguchi K (1998), Harrod R (2003), Gu W (1997), Teufel DP (2007), Mantovani F (2007), Mantovani F (2007), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), MacPartlin M (2005), Mujtaba S (2004), Wang YH (2003), Chen H (1999), Tang Z (2013), Graczyk A (2013), Graczyk A (2013), Chan HM (2001), Thomas MC (2005), Miller Jenkins LM (2015), Miller Jenkins LM (2015), Koh DI (2014), Koh DI (2014), Koh DI (2014), Li H (2015), Chen LF (2005), Shi D (2016), Wright DG (2016), Zhang X (2016), Procopio MG (2015), Tong Q (2015)	95
HSPA5	0	ERN1	1	pull down, affinity chromatography technology	Liu CY (2003), Yanagisawa K (2010)	2
HDAC6	0	HNRNPU	12	affinity chromatography technology	Watson GW (2016)	1
SPART	0	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Milewska M (2009), Milewska M (2009)	2
YWHAB	1	BRAF	12	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Qiu W (2000), Jin J (2004), Couzens AL (2013), Huttlin EL (2017), Eisenhardt AE (2016)	6
HDAC6	0	PAWR	2	affinity chromatography technology	Watson GW (2016)	1
AIRE	3	HSPA1L	2	affinity chromatography technology	Fogeron ML (2013)	1
HNRNPA1	1	HSPA8	4	affinity chromatography technology	Roy R (2014)	1
HDAC6	0	HSPA1L	2	affinity chromatography technology	New M (2013)	1
TP53	0	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Sun Y (2007), Fogeron ML (2013)	2
HDAC6	0	HSP90B1	3	affinity chromatography technology	New M (2013)	1
AIRE	3	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Akiyoshi H (2004), Fogeron ML (2013)	2
OS9	4	DNAJB11	3	affinity chromatography technology	Tyler RE (2012)	1
EGFR	5	SEC61A1	1	affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Wang YN (2010)	2
HSP90B1	3	HSPA5	0	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Hein MY (2015)	3
CLU	1	HSPA1L	2	biochemical	Kristensen AR (2012)	1
TP53	0	HSPA8	4	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Akakura S (2001), Kaur J (1996), Fogeron ML (2013), Horikawa I (2014), Matsumoto H (1994), Matsumoto H (1994), Karras GI (2017)	7
GRB2	2	DNAJB11	3	two hybrid	Wang J (2008)	1
SNW1	0	HNRNPA1	1	affinity chromatography technology	Lleres D (2010)	1
HSPA5	0	PDIA6	1	biochemical, affinity chromatography technology	Havugimana PC (2012), Li J (2013)	2
RAF1	3	YWHAB	1	two hybrid, pull down, affinity chromatography technology, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yuryev A (2003), Truong AB (2002), Van Der Hoeven PC (2000), Yuryev A (2000), Vincenz C (1996), Conklin DS (1995), Subramanian RR (2001), Rajalingam K (2005), Zhu J (2005), Couzens AL (2013), So J (2015)	11
HNRNPU	12	EP300	36	affinity chromatography technology, pull down, affinity chromatography technology, biochemical	Martens JH (2002), Martens JH (2002), Martens JH (2002), Martens JH (2002)	4
BRAF	12	RAF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Weber CK (2001), Weber CK (2001), Kilili GK (2010), Chen C (2008), Chen C (2008), Lito P (2012), Huttlin EL (2017)	7
METTL21A	0	HSPA8	4	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Cloutier P (2013), Cloutier P (2013), Huttlin EL (2015), Huttlin EL (2017), Jakobsson ME (2015)	5
CDH1	4	HSPA5	0	affinity chromatography technology, bioid	Catimel B (2005), Guo Z (2014)	2
EP300	36	SNW1	0	pull down	Leong GM (2004)	1
OS9	4	HSP90B1	3	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Christianson JC (2008), Christianson JC (2008), Brockmeier U (2011), Tyler RE (2012), Christianson JC (2012), Dersh D (2014), Dersh D (2014), Dersh D (2014), Hein MY (2015)	9
HSPA5	0	HDAC6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rao R (2010), Rao R (2010), New M (2013)	3
SNW1	0	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Zhang C (2003), Lleres D (2010)	2
GRB2	2	HSPA5	0	two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Brehme M (2009)	2
PON2	0	RUVBL2	4	affinity chromatography technology	Ewing RM (2007)	1
CDH1	4	HSPA1A	0	bioid	Guo Z (2014)	1
HSP90B1	3	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Wu B (2015), Wu B (2015), Wu B (2015), Wu B (2015)	4
CDH1	4	EGFR	5	affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, bioid	Pece S (2000), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Li J (2013), Guo Z (2014)	6
SNW1	0	HNRNPA3	0	affinity chromatography technology	Lleres D (2010)	1
FUS	0	HSPA8	4	affinity chromatography technology	Wang T (2014)	1
EGFR	5	MAP4	8	affinity chromatography technology	Yao Z (2017)	1
RPN1	2	OS9	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mueller B (2008), Christianson JC (2008), Christianson JC (2012)	3
BRAF	12	HSP90B1	3	affinity chromatography technology	Eisenhardt AE (2016)	1
UBL4A	0	HSPA1A	0	affinity chromatography technology	Xu Y (2012)	1
BRAF	12	DNAJB11	3	affinity chromatography technology	Eisenhardt AE (2016)	1
TP53	0	ERN1	1	affinity chromatography technology	Namba T (2015)	1
HSPA5	0	TG	4	pull down, pull down	Delom F (2001), Delom F (1999)	2
FUS	0	HNRNPU	12	biochemical, affinity chromatography technology	Kristensen AR (2012), Wang T (2014)	2
NAPSA	1	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGFR	5	PON2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tong J (2014), Huttlin EL (2015), Huttlin EL (2017)	3
LDLR	4	MAP4	8	two hybrid	Wang J (2011)	1
FAM187B	0	HSPA8	4	affinity chromatography technology	Huttlin EL (2017)	1
RUVBL2	4	HSPA1L	2	affinity chromatography technology	Jeronimo C (2007)	1
HNRNPA1	1	HSPA1A	0	affinity chromatography technology	Roy R (2014)	1
HSPA5	0	MAP4	8	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
TP53	0	SQSTM1	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Di Lello P (2006), Horikawa I (2014), Kang JH (2016), Kang JH (2016)	4
EP300	36	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Chang YW (2014), Chang YW (2014)	2
UCHL5	1	HSPA5	0	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology	Fang Y (2011), Fang Y (2011), Fang Y (2011), Fang Y (2011), Fang Y (2011)	5
FUS	0	DNAJC10	3	affinity chromatography technology	Wang T (2014)	1
INHA	2	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TP53	0	HNRNPU	12	affinity chromatography technology	Fogeron ML (2013)	1
EGFR	5	HSPA8	4	protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Deribe YL (2009), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), Yao Z (2017)	8
HSPA1L	2	HSPA1A	0	biochemical	Havugimana PC (2012)	1
SQSTM1	0	FUS	0	affinity chromatography technology	Tanji K (2012)	1
RUVBL2	4	HSPA5	0	affinity chromatography technology, biochemical	Jeronimo C (2007), Wan C (2015)	2
HSPA1A	0	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kaur J (1996), Fogeron ML (2013), Horikawa I (2014), Matsumoto H (1994), Matsumoto H (1994)	5
HNRNPU	12	RPN1	2	biochemical	Wan C (2015)	1
SNW1	0	UCHL5	1	affinity chromatography technology	Lleres D (2010)	1
RPN1	2	HSPA5	0	affinity chromatography technology, pull down	de Virgilio M (1999), de Virgilio M (1999)	2
EIF2AK3	3	HSP90B1	3	affinity chromatography technology	Ma K (2002)	1
HSPA8	4	HNRNPA3	0	biochemical	Havugimana PC (2012)	1
HSPA5	0	HSPA1A	0	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Hein MY (2015)	3
HSPA5	0	SQSTM1	0	unspecified method, pull down	Cha-Molstad H (2015), Cha-Molstad H (2015)	2
HSPA5	0	HNRNPA3	0	biochemical, affinity chromatography technology	Havugimana PC (2012), Li J (2013)	2
TP53	0	HSPA1L	2	affinity chromatography technology, imaging technique	Fogeron ML (2013), Chen TC (2014)	2
UBL4A	0	FUS	0	affinity chromatography technology	Xu Y (2012)	1
ANTXR1	3	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CLU	1	HSP90B1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li N (2013), Li N (2013), Hein MY (2015)	3
CBL	7	YWHAB	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Robertson H (1997), Robertson H (1997), Robertson H (1997), Subramanian RR (2001), Chernock RD (2001), Brehme M (2009), Couzens AL (2013)	7
GRB2	2	HSPA8	4	affinity chromatography technology	Brehme M (2009)	1
HNRNPU	12	HNRNPA3	0	biochemical	Havugimana PC (2012)	1
ERLIN2	2	HSP90B1	3	affinity chromatography technology	Jo Y (2011)	1
OS9	4	HSPA5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hosokawa N (2008), Christianson JC (2008), Tyler RE (2012)	3
HSPA1A	0	STIP1	1	biochemical, affinity chromatography technology	Wan C (2015), Scholz GM (2001)	2
UBL4A	0	ERLIN2	2	affinity chromatography technology	Xu Y (2012)	1
HNRNPU	12	HSP90B1	3	biochemical	Wan C (2015)	1
UBL4A	0	HSPA8	4	affinity chromatography technology	Xu Y (2012)	1
CCNJL	3	OS9	4	affinity chromatography technology	Huttlin EL (2017)	1
ERLIN2	2	HSPA5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jo Y (2011), Huttlin EL (2015), Huttlin EL (2017)	3
CDH1	4	CBL	7	bioid	Guo Z (2014)	1
HSPA5	0	ID2	0	two hybrid, affinity chromatography technology	Wang J (2011), Lee SB (2016)	2
UBQLN4	2	HSPA5	0	two hybrid, affinity chromatography technology	Matsuda M (2001), Hein MY (2015)	2
HSPA5	0	HSPA8	4	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Hein MY (2015)	3
HSPA1L	2	AMFR	2	affinity chromatography technology	Lee JH (2017)	1
YWHAB	1	TP53	0	affinity chromatography technology	Lee MK (2007)	1
EGFR	5	RPN1	2	affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Tong J (2014)	2
FAM187B	0	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ERLEC1	1	OS9	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yanagisawa K (2010), Yanagisawa K (2010), Christianson JC (2012)	3
IL12RB1	2	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HSPA5	0	LDLR	4	affinity chromatography technology, affinity chromatography technology	Jorgensen MM (2000), Sorensen S (2006)	2
SNW1	0	HSP90B1	3	affinity chromatography technology	Lleres D (2010)	1
HSPA8	4	STIP1	1	biochemical, far western blotting, pull down, pull down, pull down, biochemical	Havugimana PC (2012), Gebauer M (1998), Gebauer M (1998), Liu FH (1999), Tsukahara F (2000), Wan C (2015)	6
ID2	0	HSPA1A	0	affinity chromatography technology	Lee SB (2016)	1
HNRNPA1	1	DNAJC10	3	affinity chromatography technology	Roy R (2014)	1
HSPA5	0	HNRNPA1	1	affinity chromatography technology, affinity chromatography technology	Li J (2013), Roy R (2014)	2
TP53	0	HNRNPA1	1	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
METTL21A	0	HSPA1A	0	enzymatic study	Cloutier P (2013)	1
TP53	0	SNW1	0	affinity chromatography technology	Fogeron ML (2013)	1
GRB2	2	HSPA1L	2	affinity chromatography technology	Brehme M (2009)	1
HNRNPA1	1	HNRNPA3	0	affinity chromatography technology, affinity chromatography technology	Roy R (2014), Hein MY (2015)	2
UBL4A	0	RPN1	2	affinity chromatography technology	Xu Y (2012)	1
PRSS50	0	TOR3A	0	affinity chromatography technology	Huttlin EL (2015)	1
ITLN1	0	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PDIA6	1	RPN1	2	biochemical	Wan C (2015)	1
BRAF	12	HSPA1A	0	affinity chromatography technology	Gloeckner CJ (2007)	1
TP53	0	EGFR	5	genetic interference, genetic interference	Xie L (2013), Ye H (2016)	2
SNW1	0	FUS	0	affinity chromatography technology	Lleres D (2010)	1
EP300	36	RUVBL2	4	pull down	Karmakar S (2010)	1
CLEC18A	0	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDH1	4	MAP4	8	bioid	Guo Z (2014)	1
HDAC6	0	HSPA8	4	affinity chromatography technology, affinity chromatography technology	New M (2013), Watson GW (2016)	2
AMFR	2	HSP90B1	3	affinity chromatography technology	Jo Y (2011)	1
FUS	0	HSP90B1	3	affinity chromatography technology	Wang T (2014)	1
HSPA5	0	SEC61A1	1	unspecified method, affinity chromatography technology	Schaeuble N (2012), Schorr S (2015)	2
SNW1	0	UBL4A	0	affinity chromatography technology	Lleres D (2010)	1