PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
PPP5C	2	HSP90AA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Zeke T (2005), Silverstein AM (1997), Schuelke JP (2010), Gano JJ (2010), Cliff MJ (2006), Skarra DV (2011), Skarra DV (2011), Horibe T (2011), Taipale M (2014), Taipale M (2014), Hein MY (2015), Woo SH (2009), Woo SH (2009), Woodford MR (2016), St-Denis N (2016), Yadav L (2017), Yadav L (2017)	17
HSP90AB1	2	PTGES3	0	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down	Wang J (2011), Taipale M (2014), Taipale M (2014), Weikl T (1999), Picard D (2006), Chadli A (2008), Karagoez GE (2011)	7
ESRRB	1	CDC37	0	affinity chromatography technology	Li J (2013)	1
AURKB	2	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Huttlin EL (2015), Huttlin EL (2017)	3
PTGES3	0	CDC37	0	pull down	Sun L (2012)	1
CDK4	2	CDC37	0	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, biochemical, protein complementation assay, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Dai K (1996), Dai K (1996), Lamphere L (1997), Stepanova L (1996), Stepanova L (1996), Srivastav RK (2011), Wang H (2002), Taipale M (2014), Taipale M (2014), Huttlin EL (2015), Li J (2013), Huttlin EL (2017)	13
MCM5	1	FLNA	10	affinity chromatography technology	Drissi R (2015)	1
HSP90AB1	2	MCM5	1	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Drissi R (2015)	3
HSP90AB1	2	MYH9	19	biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Falsone SF (2005), Hein MY (2015)	3
AHSA1	0	FKBP5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014)	4
CDC37	0	CHORDC1	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
EGLN1	3	FKBP4	0	affinity chromatography technology	Song D (2013)	1
EGFR	5	STIP1	1	protein complementation assay	Deribe YL (2009)	1
FLNA	10	MYH9	19	biochemical, affinity chromatography technology	Havugimana PC (2012), Hein MY (2015)	2
MCM5	1	MYH9	19	affinity chromatography technology	Drissi R (2015)	1
HSP90AA1	7	CHORDC1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gano JJ (2010), Gano JJ (2010), Gano JJ (2010), Taipale M (2014), Taipale M (2014), Hein MY (2015)	6
HSP90AA1	7	CDK4	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsutsumi S (2012), Wang H (2002), Taipale M (2012), Varjosalo M (2013), Huttlin EL (2015), Woodford MR (2016), Huttlin EL (2017)	7
FKBP5	0	CDK4	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Huttlin EL (2015), Huttlin EL (2017)	4
EGFR	5	FKBP4	0	protein complementation assay	Deribe YL (2009)	1
STIP1	1	CCDC117	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Huttlin EL (2015), Huttlin EL (2017)	4
FKBP4	0	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014), Huttlin EL (2017)	5
HSP90AA1	7	HIF1A	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hogenesch JB (1997), Qian DZ (2006), Kong X (2006), Kubo T (2004), Zhou J (2004), Fu B (2007), Choi YK (2010), Choi YK (2010), Lee JM (2011), Liu YV (2007), Liu YV (2007), Katschinski DM (2004), Katschinski DM (2004), Katschinski DM (2004), Trisciuoglio D (2010), Trisciuoglio D (2010), Ueda K (2008), Sun H (2013), Kawanami D (2009), Prince TL (2015), Prince TL (2015), Isaacs JS (2004), Lee SH (2015)	23
TTC4	1	AHSA1	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
FGFR3	7	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Laederich MB (2011), Laederich MB (2011), Laederich MB (2011)	3
HSP90AA1	7	CDK7	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Huttlin EL (2015), Huttlin EL (2017)	3
CDC37L1	0	TTC4	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
MCM5	1	FKBP5	0	biochemical	Kristensen AR (2012)	1
CDK7	0	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Huttlin EL (2015), Huttlin EL (2017)	3
HSP90AA1	7	TTC4	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gano JJ (2010), Skarra DV (2011), Taipale M (2014), Taipale M (2014)	4
HSP90AB1	2	TTC4	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014)	4
HSP90AB1	2	ESRRB	1	affinity chromatography technology, two hybrid, affinity chromatography technology	Prince TL (2015), Prince TL (2015), Li J (2013)	3
MCM5	1	FANCA	5	affinity chromatography technology	Karras GI (2017)	1
CDK9	3	FKBP5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Varjosalo M (2013), Varjosalo M (2013), Taipale M (2014), Taipale M (2014), Huttlin EL (2015), Huttlin EL (2017), Luo K (2017)	8
CDK7	0	FKBP5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGFR	5	AIP	1	protein complementation assay	Deribe YL (2009)	1
AHSA1	0	STIP1	1	biochemical	Wan C (2015)	1
EGFR	5	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Citri A (2002), Yang S (2006), Shimamura T (2005), Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014)	8
PTGES3	0	PPP5C	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schuelke JP (2010), Taipale M (2014), Taipale M (2014), Yadav L (2017)	4
HSP90AB1	2	AHSA1	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zurawska A (2010), Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014), Wan C (2015), Wolfgeher D (2015), Synoradzki K (2015)	8
CDK7	0	CDK9	3	enzymatic study, biochemical, enzymatic study	Kim JB (2001), Garcia-Martinez LF (1997), Larochelle S (2012)	3
TTC4	1	CHORDC1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Huttlin EL (2017)	3
HSP90AB1	2	FLNA	10	affinity chromatography technology, affinity chromatography technology, imaging technique	Falsone SF (2005), Hein MY (2015), Chen TC (2014)	3
FKBP5	0	AURKB	2	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
MCM5	1	HSP90AA1	7	biochemical, affinity chromatography technology	Kristensen AR (2012), Drissi R (2015)	2
CDK9	3	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
HSP90AA1	7	MAPK7	1	affinity chromatography technology	Taipale M (2012)	1
CDK4	2	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CDC37L1	0	FKBP5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014)	4
PPP5C	2	STIP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Skarra DV (2011), Skarra DV (2011), Yadav L (2017), Yadav L (2017)	4
FKBP4	0	HSP90AA1	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology	Li J (2011), Esposito V (2012), Schuelke JP (2010), Gano JJ (2010), Skarra DV (2011), Shimamoto S (2010), Shimamoto S (2010), Kristensen AR (2012), Taipale M (2014), Taipale M (2014), Graumann K (2000), Graumann K (2000), Sun L (2012), Huttlin EL (2017)	14
EGFR	5	AHSA1	0	protein complementation assay	Deribe YL (2009)	1
FKBP5	0	CHORDC1	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
FKBP5	0	STIP1	1	pull down	Li J (2011)	1
CDC37	0	FKBP4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014)	4
HSP90AA1	7	AHSA1	0	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, genetic interference, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Panaretou B (2002), Panaretou B (2002), Panaretou B (2002), Mollapour M (2010), Tsutsumi S (2012), Tsutsumi S (2012), Gano JJ (2010), Zurawska A (2010), Taipale M (2014), Taipale M (2014), Mollapour M (2014), Wan C (2015), Wolfgeher D (2015), Sun L (2012), Sun L (2012), Woodford MR (2016), Woodford MR (2016), Woodford MR (2016), Synoradzki K (2015)	19
PPP5C	2	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Skarra DV (2011), Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014), Hein MY (2015), St-Denis N (2016), Yadav L (2017), Yadav L (2017)	9
CDC37	0	FKBP5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014)	4
CHORDC1	1	FKBP4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014)	4
HSP90AA1	7	CDC37L1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gano JJ (2010), Taipale M (2014), Taipale M (2014), Hein MY (2015), Scholz GM (2001), Scholz GM (2001)	6
FKBP5	0	TTC4	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
PPP5C	2	CDC37	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Skarra DV (2011), Skarra DV (2011), Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014), Yadav L (2017)	7
HSP90AA1	7	PTGES3	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down	McLaughlin SH (2002), Mollapour M (2010), Kovacs JJ (2005), Giommarelli C (2010), Tsutsumi S (2012), Lee YT (2004), Schuelke JP (2010), Sarkar S (2012), Gano JJ (2010), Zelin E (2012), Obermann WM (1998), Wang J (2011), Weaver AJ (2000), Donze O (2001), Shimamura T (2012), Chan CT (2008), Chan CT (2008), Graumann K (2000), Martinez-Yamout MA (2006), Chadli A (2010), Woo SH (2009), Woo SH (2009), Woo SH (2009), Ni L (2010), Chadli A (2008), Picard D (2006), Wochnik GM (2004), Woodford MR (2016), Scholz GM (2001), McLaughlin SH (2006), Sun L (2012), Woodford MR (2016), Lepvrier E (2015)	33
PTGES3	0	AIP	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Schuelke JP (2010), Taipale M (2014), Taipale M (2014), Kazlauskas A (2000)	4
HSP90AA1	7	MYH9	19	affinity chromatography technology	Falsone SF (2005)	1
PTGES3	0	AHSA1	0	pull down, affinity chromatography technology	Sun L (2012), Sun L (2012)	2
FANCA	5	HSP90AA1	7	two hybrid	Reuter TY (2003)	1
FKBP4	0	PTGES3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Scholz GM (2001)	3
AIP	1	HSP90AA1	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Li J (2011), Schuelke JP (2010), Taipale M (2014), Taipale M (2014), Kazlauskas A (2000)	5
CDK9	3	CDC37	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mak AB (2010), Varjosalo M (2013), Huttlin EL (2015), Li J (2013), Huttlin EL (2017)	5
CDC37	0	AHSA1	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CHORDC1	1	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Hein MY (2015)	3
FKBP5	0	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014)	4
CDK9	3	STIP1	1	affinity chromatography technology	Varjosalo M (2013)	1
HSP90AA1	7	CCDC117	1	affinity chromatography technology, affinity chromatography technology	Gano JJ (2010), Huttlin EL (2017)	2
AIP	1	CDC37	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014)	4
HIF1A	1	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	van de Sluis B (2009), Trisciuoglio D (2010), Ueda K (2008), Prince TL (2015), Prince TL (2015)	5
CDC37L1	0	CHORDC1	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
EGFR	5	PTGES3	0	affinity chromatography technology	Tong J (2014)	1
HIF1A	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EGFR	5	MYH9	19	affinity chromatography technology	Chiu HC (2012)	1
AIP	1	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014)	4
HSP90AA1	7	FLNA	10	affinity chromatography technology	Falsone SF (2005)	1
AHSA1	0	PPP5C	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014)	4
PPP5C	2	CDK9	3	affinity chromatography technology, bioid, affinity chromatography technology	Yadav L (2017), Yadav L (2017), Yadav L (2017)	3
EGLN1	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Song D (2013), Song D (2013), Song D (2013), Song D (2014), Song D (2014)	5
CDC37	0	AURKB	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Huttlin EL (2015)	3
FANCA	5	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, genetic interference	Karras GI (2017), Karras GI (2017), Karras GI (2017)	3
MAPK7	1	CDC37	0	affinity chromatography technology, affinity chromatography technology	Erazo T (2013), Erazo T (2013)	2
EGLN1	3	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Song D (2013), Song D (2013), Song D (2013), Song D (2014), Song D (2014)	5
CDC37L1	0	PPP5C	2	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CDC37	0	TTC4	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014)	4
PTGES3	0	FKBP5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schuelke JP (2010), Taipale M (2014), Taipale M (2014)	3
CDC37L1	0	STIP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Scholz GM (2001)	3
CDC37	0	CDK7	0	pull down, affinity chromatography technology	Stepanova L (1996), Huttlin EL (2015)	2
ESRRB	1	EGFR	5	affinity chromatography technology	Li J (2013)	1
HSP90AB1	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Cheng MB (2010), Gano JJ (2010), Skarra DV (2011), Kristensen AR (2012), Taipale M (2014), Taipale M (2014), Wan C (2015), Hein MY (2015)	8
FKBP4	0	STIP1	1	pull down	Li J (2011)	1
PTGES3	0	STIP1	1	biochemical	Wan C (2015)	1
CDK9	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mak AB (2010), Taipale M (2012), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	5
CDC37L1	0	FKBP4	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CDC37L1	0	CDC37	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
HSP90AB1	2	CCDC117	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Huttlin EL (2015)	3
HSP90AB1	2	CDC37	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Erazo T (2013), Erazo T (2013), Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014), Hein MY (2015), Li J (2013), Karras GI (2017), Synoradzki K (2015)	10
HSP90AA1	7	ESRRB	1	affinity chromatography technology, two hybrid, affinity chromatography technology	Prince TL (2015), Prince TL (2015), Li J (2013)	3
EGFR	5	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	6
EGLN1	3	PTGES3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Song D (2013), Song D (2013), Song D (2013), Song D (2014), Song D (2014)	5
HIF1A	1	EGLN1	3	pull down, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Percy MJ (2006), Baek JH (2005), Yoo YG (2008), Chowdhury R (2009), Choi YK (2010), Park MH (2014), Park MH (2015), Park MH (2015), Barth S (2007), Song D (2013), Guo J (2016), Kumar P (2015)	12
CDC37L1	0	HSP90AB1	2	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid	Wang J (2011), Taipale M (2014), Taipale M (2014), Rolland T (2014)	4
HSP90AB1	2	STIP1	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology	Havugimana PC (2012), Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014), Wan C (2015), Chadli A (2008), Huttlin EL (2017)	8
EGFR	5	CDC37	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lavictoire SJ (2003), Foerster S (2013), Li J (2013), Li J (2013)	4
HIF1A	1	PTGES3	0	affinity chromatography technology	Katschinski DM (2004)	1
STIP1	1	HSP90AA1	7	pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Scheufler C (2000), Johnson BD (1998), Mollapour M (2010), Li J (2011), Kundrat L (2010), Tsutsumi S (2012), Sarkar S (2012), Gano JJ (2010), Skarra DV (2011), Horibe T (2011), Brinker A (2002), Taipale M (2014), Taipale M (2014), Mollapour M (2014), Graumann K (2000), Hein MY (2015), Chadli A (2010), Chadli A (2008), Woodford MR (2016), Scholz GM (2001), Sun L (2012), Woodford MR (2016), Huttlin EL (2017)	23
MAPK7	1	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Erazo T (2013), Erazo T (2013), Erazo T (2013)	3
EGFR	5	PPP5C	2	protein complementation assay	Deribe YL (2009)	1
HSP90AA1	7	AURKB	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Taipale M (2012), Fogeron ML (2013), Huttlin EL (2015), Huttlin EL (2017)	5
FKBP5	0	HSP90AA1	7	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Nair SC (1997), Nair SC (1997), Li J (2011), Schuelke JP (2010), Gano JJ (2010), Skarra DV (2011), Horibe T (2011), Kristensen AR (2012), Taipale M (2014), Taipale M (2014), Graumann K (2000), Ni L (2010), Luo K (2017)	13
HSP90AA1	7	CDC37	0	x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Roe SM (2004), Silverstein AM (1998), Mollapour M (2010), Basso AD (2002), Tsutsumi S (2012), De Nardo D (2005), Sarkar S (2012), Gano JJ (2010), Taipale M (2012), Skarra DV (2011), Zhang H (2004), Taipale M (2014), Taipale M (2014), Mollapour M (2014), Hein MY (2015), Hein MY (2015), Li J (2013), Woodford MR (2016), Shao J (2003), Scholz GM (2001), Sun L (2012), Sun L (2012), Woodford MR (2016), Synoradzki K (2015)	24
FGFR3	7	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Laederich MB (2011), Taipale M (2012)	2
FKBP5	0	EGLN1	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
FGFR3	7	CDC37	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Laederich MB (2011), Laederich MB (2011), Laederich MB (2011)	3
PPP5C	2	CHORDC1	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
AIP	1	STIP1	1	pull down	Li J (2011)	1
AHSA1	0	FKBP4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014), Sun L (2012)	5
AHSA1	0	CHORDC1	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CDK9	3	AIP	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3